miRTarBase - #MIRT461013


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pre-miRNA Information
pre-miRNA hsa-mir-4436b-1   
Genomic Coordinates chr2: 110086433 - 110086523
Description Homo sapiens miR-4436b-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-4436b-2   
Genomic Coordinates chr2: 110284853 - 110284943
Description Homo sapiens miR-4436b-2 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4436b-3p
Sequence 60| CAGGGCAGGAAGAAGUGGACAA |81
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs760150076 9 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SYT7   
Synonyms IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII
Description synaptotagmin 7
Transcript NM_004200   
Expression
Putative miRNA Targets on SYT7
3'UTR of SYT7
(miRNA target sites are highlighted)		 
>SYT7|NM_004200|3'UTR
   1 GTGGGGCCAAGGGAGGCCCAGGGGGCCGAGGGCCCAGGTCCCCATCATGCCCTCACCACTTTATGCACAACGCCCGGCCT
  81 GAGCCCCCTGCCATAGGGAGGGGAGGACCCTGAGGGCTCAGCCAGGGAGGGGTCCCAGGACTCAACTGGGCCCCGTTTCT
 161 AGGAAGTACCAGCCCCATCCCCCACAGTCCAGCTCCGGGGAAGGGGCTCTGGGAGGCATTTTCCTGCTTTGCCCCTTTTC
 241 TTCCTGACTTACTAATACTAAAGAAGTTGGGGGAGCTCGAGAGCCAGACGGCCAGACAGGCAGACCCCTCCAGAGGCCCG
 321 CCAGGTGGGCATGGTCCCCCATTTTCTTTAAGGCAGCACCTGGAGTGGAGAGAGGCCACTCCCTCTCCAGCCCCCGATGT
 401 GGACCCGGGGAGGGGAGGCTGAGGCGTTTGGCCCCGGCCTGGCCAGGAGAGGCCCATCCCCAGGGCAGTTTCAGGTGCCG
 481 GCTGGGCCCTGAATGTCGAGGATAGTATATAGCCCGCTCCTGGGTCCTGGAGCTGTGGCCCTTTGTACTCGTGTTGTGTC
 561 CATTGTGTGTGTGCGTGGGGACAGAGGCCTGGAAATGCGGAGGACTATACAGAGAAGGCAGGTTTTGTGAAGGCCAGGCA
 641 GGGTTGGAGGCCGGGGGTGTGAGAGGAGAGGCCCATAGGGCTGAGTGGGGTCGGGTGAGGCAGAGGTCAGAAACAGAAGA
 721 GCTGCAGTTGCTGGAGCTGGGCTGAGAACTGGGCTGCCTCCTGCCATCCCCCCGTCTCCTCCCCTTCTCCCCTTGGTGCC
 801 CCCCTCTGCTCAGAATCTGAAGTAGTTCCCTCCTCAGCAATTTCATCTCTTGAACACTGACTCACACCTTTTAGGCACCT
 881 ACTGTGTGCATAGCATTCCACCAGGACTCATCTCCCTTCCTTCTCAGGGGGTCCCGAGCCCCGACTAGCTTTGCCCTAAC
 961 TCCTTCATCAAAAGACCCCCCGCCAGCTTCCCACACCTCATACGCAGCCACATCTGCCCTATTCTCCATGCTTTCCAGCT
1041 TGCCTGCCCTTCCTCATCTCTCCCTGCCTGTGCAGACCTCCACCCTTCTTTCCTCCACCCCTCCATCCCCCAATGCTTGT
1121 AGACCTTCCATTCATTCCGTCTCATCGTGCGTGGTCTCTGATCGTCCATCACCTGACCTTCTCCAGGACTGTCTTCTCAC
1201 CCTTCCCCACTCCCTGGTCCCCGGGAGCAGCTCCTTCTGCCCGACTCACTCACAGTGCAGGGAAAGGAGGCAGGGAAAAG
1281 ACCAGGATTCTGTGAGTTCTGAGGTTGCCACACACAAAGAAGCTGTGGTTTCTCTGCCTCGGCCACTGATGAGACTAAAA
1361 CTGGCTTCCCCTTGGAGACGGCAGATTTCAGGCTGATCCCTGCTTAAGCCCTCTCATCCCCACGCTGGTCCTGGTATTGA
1441 TACAAGACCCAGCTGGTGACAAAGCCTCCAATCCTGGGGGTCCACGAGCCTGGGCCTGACATTCCCAGAACTACCGCCAG
1521 GTGGCGCCAGGCCCCCACAGTCTGTGGCCGTGGTCTTAGCCCCCAGTTCCACTCTGGATGGGCCTGTGACACCCCAAAGA
1601 GAAGAAGGGGACTCTGGATAGGGTCCCCACATCCAGGGCGTGGGGAGACCATTGGCATTTGGGAACCATTTTCCTTCGAA
1681 CGGCTTCCCCTTGAGCTGAGCATTCTGCTTGCTGCAGTAGACGGGTCGCCTTTTGCCCATACCGAAATTTTCTGAAATTA
1761 AATCGCACACCCCCACCATTTCCTCTCCCTGGGATCTGGAGGAACATCATACATAGTAGGTGAATCGTTTTGTAGAGTGA
1841 AGAATGCTAATGTAAAGCAAATAGTCACCCACGTTCCTTGTAAATCCAAATGTTTCTATATTGTAGCTTTGCTTAAAATG
1921 GGGTCGGCCCCAACTGCATCCTCCTCTTTGGCGGGCTGGGGAGCGGCCCCCAGCCGGGACGGGAGGGCAGCGACCCCGAG
2001 GCCTCGTGGACGTGGGAGAGAGTGTGGTGGGAAGTCTTGAGCGGAGGAGGGGATCTGCCCTTCTCCACTCCTCTCTTGGA
2081 TCCGCCTCGGTTTCCTGTCCCCCCACCACCCGCCTGCCCCGCGGAAGACCGCCCAGTGAGCCAGCCCCCACCTTCCAGGC
2161 GCCTTCGCCCTGGGGATCCAACCAACTTGTATCGAGTGGGCGGGGCAACGGCTCCCCATTTTTCCCGAGCCCCGCCCACA
2241 GAGCTCTTAGCCAATCCTATGCAGAGAGCATCTCCTGGCAGGGGTCTCTTCCCAACCAGACCCCACCCAGGCACATTAGC
2321 GACCAGGCTTGGGCTTCCCCAGCGCCCCACCACCACCACGTGCAGGTGGAGCTCTGGGATGCTATGTTGGGGCGGCAAGC
2401 GGTGGGCCGAGGGCCGGGTAGGCTAGCACGGGAGGTAAGGGTGGTATGGGATGGGGCGGGGGCGGTCTAGGGCAATAGGA
2481 GAGCAGAGAATGGGGGAACTTGAGGGTGGGGGGAGGGCACCGGAGCCTTGCCACCATCCCAGGACTTTGGGCAAGTCACC
2561 CGCACTCCCTGGGCCTCGGTTTCCCCATCTGTAAAATGATGGTAATAATACTTCACCTACCTCATAGGGGAGGTTGTGAG
2641 GCCACCATCACCTGACCTGGGGGTCAAGGCAGGAGGACTCCGAAGGTGCTACCCGTGAGCAAAGTGTAATTACCGAATCC
2721 TGACTGCAAGGCCCACCTGCCCCTCCCCCACAGAGCCTCCAGAGCTAGCTGAGGCCAACGCAGGCCCATCCGTCTCTTCA
2801 CTCTGTCGCAGGCCCTTTCATGGGCTTCGTCTGCCATCTTTGTGGGTGCCCTAGACTTAGTCCTTATCTTGTCCTGGTTT
2881 CCTTTCTTGTGACCATCTCCCCATGAAAGTGCTGTACAAATTCCACCCGCCCCAGGACCCCCGCACCTGCCCTCTGGCAC
2961 CAGATGCCAGGGAAGGGACAGAGGAAAACAGCCACAAACAAGCCAGGGGGGCTCCCCGGAGCCCCAGGGGTGGGGATTGG
3041 TGGCCACTGTTTGTATGTTCTTGAGTGCAAGTGTTTTATAAAAAATAAAACAAAAACCCACCATCACAAAAAAAAAAATT
3121 TTGCAGCGAAGAGAAATGAAGAAAAACTGAAGAAAAAAAAAAAACAGGAAAAAAAGAACCATACAAAATTTTTCCACCAC
3201 ACATACCCTCTAAGCCAGCAAGATTTCCTCTTTGCAAAATCATATTTTTGTGGGAATGGGCCCTGCTTTTTGTGGCAAGG
3281 CCTGTTCTGATTAATAAAGGATCGTGAAAAAGTAGGGCCTTGGCTGTTTCCTCCGTGGGTCCCAGCCCTCCCTCACCTCC
3361 CTGGGGGCAGAGGCAGTGGGGTGAAGGGGATGGGGGCCCCGGGGCTGAGCCTCCCCTCAGTGTGTCACCTTTGGGATTTG
3441 ACTTCACTGGTGACCAGGCCCTTCCCGAGTGTCCAGCCATCCTCAGATCTCTATAGAATATGATCCCACTGGCTTCCCAG
3521 AAAGCAGAGAGGCAGCTACATCTCCCAGATCAGGCCTGACACAAGGCTTTTTGGGAGTAGAGTCCTCTCTAGGCCTCAGG
3601 GGTGCCCTCCAGGGTCACCCAGCCTGACGTCCCCTCCCTCAGTTCCCAGAGGACACTTGCCACCCTCCAAGGCAGCTCAG
3681 ACAAACCAAAGGGGGACGCTCCAGCTTTCCCACCACCATCCATGGGGCCACTGTAGTTTCAGGCCAGCGCCTCCTTCCTG
3761 GTCCCTGAGGTGGGAAAAGGAAAGACAATGAGCTCTGTGTCTGTTGGCTGGACCTGCGGCTTCTCTCAGCCCTCTTCTAG
3841 TTTCATTCTTTAGGATTAGAAAAGTCTCTTCCACTCAATAGAACAGGTTCCAGCCTGAGGTGTGGGAAGCTGGGTTGTAA
3921 TCCCTTCTGCAGCCTCTGTGGCCCTGGGCAAGCTCTTTCCTTCCACCTGTTTCTTCTGGCCACAACAAAGCAATAACCAT
4001 CCCCATCCCCTGCCCTTTCTTCCCCACCCAGCCCAGGGGAAGCTGAGCCCCCGCAGCTCTCAGGGTACTTCAGAAGGAAG
4081 GTGCTACATCTGGTTCAGACACAGGCACAAAAGGAACGAGCACATCCCCATTGTCATGTGTCCACCTGCTGGCCCCTGCC
4161 CCCACCAGGAGTGAAGCGGGCCATCCCATCCGCCCTCTGCTCCCAGCACTTGGGGCCAGCAGCTGCCTCCCGGAGCTGCA
4241 CTAAGTACCCCATCCAAAGCTGTCTGTCCCTCATTTCCCACAACCTGGTTTAGATATCACTTCTGATCTCTGTTCCAGAG
4321 ATCAGAGGAAGCCCCGGGGTCAGGTAAGTAGCCTCAGGGGCTCCCTTGGCCAGAGCTTCTGTTCAGGCGCTCTCCATGAA
4401 AGCAGCCCTGGAAAACTGAGCCTGAAGTCAGAGACAGCTCAGGCCCAGCACAGGGGGCAGTCCCTTGCCACTGGCTCGGG
4481 CCCTTCCCTGGACTTTTTGCCTTCCTCCATTTTTGCTTCTCTGGGTCTGTCTTCGTCCATGCCTGCTCTGAGATGCTCCC
4561 CCACCCCTCCCTGTACCTGGGACCACCGCCCTCTGGTGTTTTCTTTCTCCTGTGAGTCCCCCCCTGGATACTGCTGCTTT
4641 CTGGAAGGCTGTCCTGGGTTACGTCCTGCGCTCCTCTCCCTCCCACGCAAAGACAACCAGAAGGACAAGCCTTGAGCACG
4721 CCGATGCCCCAGCTCGTGGCTCCCCAGACCATCTGTTTCCCGTGAAGACGCCCCGCTCCCCGTGTCTGTGTCCTGCGTGT
4801 ATGTGTCGTGTCTTGTGTAGATTGTGAGCCCCCTGGGCAGGGATCCCTGTCTGCATACATGTTCCATGTGGCACGCCCAG
4881 GTGTGCTAATAAACGTTCATCTTCAGAACAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aacAGGU--GAA-----GAA-GGACGGGAc 5'
             ||||  |||     ||| |||||||| 
Target 5' ttcTCCATGCTTTCCAGCTTGCCTGCCCTt 3'
 1022 - 1051 161.00 -19.90
2 
miRNA  3' aacAGGUGAAGAAGGACGGGAc 5'
             ||| | ||  |||||||| 
Target 5' ccaTCCCCATC-CCCTGCCCTt 3'
 3997 - 4017 158.00 -17.20
3 
miRNA  3' aacaGGUGAAGAAGGACGGGAc 5'
              |||| |    ||||||| 
Target 5' gcagCCACAT----CTGCCCTa 3'
 1004 - 1021 148.00 -16.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31490739 11 COSMIC
COSN30542836 116 COSMIC
COSN1540017 257 COSMIC
COSN31578531 289 COSMIC
COSN31533004 300 COSMIC
COSN31535017 346 COSMIC
COSN26525297 798 COSMIC
COSN29439522 891 COSMIC
COSN23588186 1004 COSMIC
COSN10090203 1187 COSMIC
COSN15793650 1534 COSMIC
COSN26489370 2371 COSMIC
COSN19605077 2464 COSMIC
COSN30164447 2623 COSMIC
COSN2508374 2640 COSMIC
COSN8584386 2714 COSMIC
COSN26569205 2715 COSMIC
COSN28825035 2728 COSMIC
COSN1135586 2751 COSMIC
COSN31521720 2758 COSMIC
COSN31555438 2838 COSMIC
COSN31483841 2842 COSMIC
COSN31606222 2909 COSMIC
COSN31555443 2917 COSMIC
COSN28731386 2949 COSMIC
COSN5915958 3014 COSMIC
COSN25415731 3091 COSMIC
COSN23671010 3118 COSMIC
COSN30544871 3123 COSMIC
COSN15920893 3138 COSMIC
COSN28731475 3141 COSMIC
COSN20108341 3153 COSMIC
COSN31585760 3157 COSMIC
COSN31618028 3188 COSMIC
COSN16389581 3198 COSMIC
COSN29350591 3259 COSMIC
COSN21804185 3303 COSMIC
rs3741259 3749 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs749555398 1 dbSNP
rs1332389452 2 dbSNP
rs1046632411 4 dbSNP
rs558621458 8 dbSNP
rs189778032 11 dbSNP
rs1471691249 13 dbSNP
rs1163767505 16 dbSNP
rs1364444671 17 dbSNP
rs753134254 21 dbSNP
rs569580920 22 dbSNP
rs1038793726 23 dbSNP
rs755559433 25 dbSNP
rs1484214899 26 dbSNP
rs202186007 27 dbSNP
rs1209911476 28 dbSNP
rs1441467165 30 dbSNP
rs1248484090 33 dbSNP
rs561002493 34 dbSNP
rs769689841 39 dbSNP
rs1220385249 41 dbSNP
rs1326472037 49 dbSNP
rs1287592602 51 dbSNP
rs1053400416 63 dbSNP
rs1197378814 64 dbSNP
rs1263089725 70 dbSNP
rs752205455 71 dbSNP
rs928566605 72 dbSNP
rs529833746 75 dbSNP
rs186202749 76 dbSNP
rs1159926012 81 dbSNP
rs548801217 84 dbSNP
rs948718547 86 dbSNP
rs915869347 90 dbSNP
rs1469570813 93 dbSNP
rs1337711924 94 dbSNP
rs1315875291 102 dbSNP
rs1245796923 114 dbSNP
rs1204102406 117 dbSNP
rs1309206904 119 dbSNP
rs1350764829 120 dbSNP
rs759152240 125 dbSNP
rs111352609 126 dbSNP
rs963080627 134 dbSNP
rs908623804 142 dbSNP
rs983381814 145 dbSNP
rs3802949 146 dbSNP
rs1204695127 149 dbSNP
rs1459684272 151 dbSNP
rs546212000 154 dbSNP
rs1029885405 155 dbSNP
rs1417934337 155 dbSNP
rs1363348509 164 dbSNP
rs1317891365 179 dbSNP
rs998574050 182 dbSNP
rs975605382 185 dbSNP
rs902716284 188 dbSNP
rs1387251757 196 dbSNP
rs964354439 197 dbSNP
rs1017649240 199 dbSNP
rs1396179844 202 dbSNP
rs1390834876 207 dbSNP
rs1011237442 224 dbSNP
rs1347932556 246 dbSNP
rs1448033407 262 dbSNP
rs1224550708 268 dbSNP
rs1418420125 272 dbSNP
rs1321809086 276 dbSNP
rs375852156 278 dbSNP
rs1031407865 283 dbSNP
rs770874000 289 dbSNP
rs907011230 290 dbSNP
rs1198535368 297 dbSNP
rs1198188270 298 dbSNP
rs1045692300 299 dbSNP
rs1430008612 300 dbSNP
rs898458018 300 dbSNP
rs1172824126 304 dbSNP
rs760634457 314 dbSNP
rs948586503 316 dbSNP
rs1461602931 317 dbSNP
rs1037563478 319 dbSNP
rs1367476707 320 dbSNP
rs1406129419 323 dbSNP
rs1283129356 330 dbSNP
rs894481154 336 dbSNP
rs1038818134 339 dbSNP
rs1216680308 352 dbSNP
rs941364717 357 dbSNP
rs908642528 364 dbSNP
rs368480180 370 dbSNP
rs934172287 377 dbSNP
rs1490358439 379 dbSNP
rs866122911 381 dbSNP
rs921193491 382 dbSNP
rs1228458009 383 dbSNP
rs990046820 384 dbSNP
rs1420540024 388 dbSNP
rs773289636 391 dbSNP
rs1428117075 392 dbSNP
rs563362843 394 dbSNP
rs543376941 395 dbSNP
rs574596767 396 dbSNP
rs148702966 397 dbSNP
rs971103971 398 dbSNP
rs1289796988 405 dbSNP
rs964684752 406 dbSNP
rs1013723166 407 dbSNP
rs1359546640 411 dbSNP
rs1315353089 412 dbSNP
rs541507129 415 dbSNP
rs1033897044 417 dbSNP
rs1389958628 418 dbSNP
rs373148138 419 dbSNP
rs572182874 425 dbSNP
rs1216295434 426 dbSNP
rs780034323 432 dbSNP
rs957043404 435 dbSNP
rs1031857687 436 dbSNP
rs1184841077 437 dbSNP
rs545031192 443 dbSNP
rs78847698 444 dbSNP
rs958533519 445 dbSNP
rs1412330219 451 dbSNP
rs117566820 458 dbSNP
rs1344975237 459 dbSNP
rs1051152182 474 dbSNP
rs781475681 479 dbSNP
rs921057803 480 dbSNP
rs1272064123 488 dbSNP
rs1312252244 493 dbSNP
rs1352153427 494 dbSNP
rs538580466 497 dbSNP
rs757621115 498 dbSNP
rs1282632941 500 dbSNP
rs548384711 503 dbSNP
rs924296817 508 dbSNP
rs1038279683 512 dbSNP
rs1232824534 514 dbSNP
rs569933820 515 dbSNP
rs887083952 516 dbSNP
rs971011651 518 dbSNP
rs553326640 524 dbSNP
rs1047140904 525 dbSNP
rs1471160345 525 dbSNP
rs1178292860 526 dbSNP
rs934038064 529 dbSNP
rs1408556972 534 dbSNP
rs536401466 539 dbSNP
rs73496241 541 dbSNP
rs536205384 550 dbSNP
rs975585602 551 dbSNP
rs1330012769 553 dbSNP
rs1442286574 559 dbSNP
rs942868939 562 dbSNP
rs868074429 563 dbSNP
rs915502965 564 dbSNP
rs1162341573 569 dbSNP
rs182501346 571 dbSNP
rs957274848 572 dbSNP
rs924240230 573 dbSNP
rs751985312 574 dbSNP
rs1004229800 575 dbSNP
rs564033014 575 dbSNP
rs201235198 576 dbSNP
rs1439341960 577 dbSNP
rs1480281792 587 dbSNP
rs79712007 598 dbSNP
rs1024055481 599 dbSNP
rs1327579623 603 dbSNP
rs1368110018 606 dbSNP
rs1406734429 607 dbSNP
rs1283769032 608 dbSNP
rs1012786756 610 dbSNP
rs958540000 618 dbSNP
rs1017274700 623 dbSNP
rs1275155256 639 dbSNP
rs1273361140 641 dbSNP
rs1341696324 649 dbSNP
rs369763990 650 dbSNP
rs758877065 652 dbSNP
rs569057549 653 dbSNP
rs935810621 655 dbSNP
rs752221992 669 dbSNP
rs1280633364 671 dbSNP
rs78906365 672 dbSNP
rs1490308404 675 dbSNP
rs1197162589 677 dbSNP
rs1374488773 683 dbSNP
rs1444895867 688 dbSNP
rs1475551521 690 dbSNP
rs1387792161 691 dbSNP
rs903116077 691 dbSNP
rs368229816 692 dbSNP
rs566168274 695 dbSNP
rs901293882 704 dbSNP
rs552709640 714 dbSNP
rs1320017927 731 dbSNP
rs1326754543 733 dbSNP
rs916911847 743 dbSNP
rs942881366 751 dbSNP
rs915383132 767 dbSNP
rs1394727778 769 dbSNP
rs1340203908 771 dbSNP
rs1054455111 773 dbSNP
rs1208529495 774 dbSNP
rs72914250 774 dbSNP
rs1264340170 780 dbSNP
rs924188096 783 dbSNP
rs974285900 789 dbSNP
rs1192037373 798 dbSNP
rs1245798661 800 dbSNP
rs3019201 801 dbSNP
rs1407255631 803 dbSNP
rs1015855241 804 dbSNP
rs200117942 805 dbSNP
rs749365936 808 dbSNP
rs543704331 828 dbSNP
rs917028360 829 dbSNP
rs1363253078 831 dbSNP
rs991223045 832 dbSNP
rs1454695221 837 dbSNP
rs1315852977 848 dbSNP
rs191576157 854 dbSNP
rs958793002 858 dbSNP
rs1243265478 862 dbSNP
rs955395836 865 dbSNP
rs1016726975 872 dbSNP
rs1208486602 877 dbSNP
rs1265895684 881 dbSNP
rs1005794789 883 dbSNP
rs1183767776 885 dbSNP
rs1254908430 887 dbSNP
rs1421474722 888 dbSNP
rs996958905 901 dbSNP
rs951332845 903 dbSNP
rs1452841730 906 dbSNP
rs1156659657 907 dbSNP
rs1033484586 911 dbSNP
rs1000044125 912 dbSNP
rs1025503557 931 dbSNP
rs756028366 932 dbSNP
rs902976371 932 dbSNP
rs1309865748 935 dbSNP
rs560933104 936 dbSNP
rs1228214377 940 dbSNP
rs569765263 942 dbSNP
rs572475975 943 dbSNP
rs1039776982 946 dbSNP
rs1006943648 948 dbSNP
rs893969814 958 dbSNP
rs879214427 970 dbSNP
rs893837276 975 dbSNP
rs367922422 976 dbSNP
rs1482027950 977 dbSNP
rs936983522 980 dbSNP
rs760544501 981 dbSNP
rs558489981 982 dbSNP
rs559929641 982 dbSNP
rs941538749 982 dbSNP
rs34043604 997 dbSNP
rs1177500439 1001 dbSNP
rs1299941656 1003 dbSNP
rs1358792877 1003 dbSNP
rs983063854 1024 dbSNP
rs955593145 1026 dbSNP
rs1046666720 1030 dbSNP
rs949710487 1032 dbSNP
rs1224493523 1035 dbSNP
rs1300213825 1036 dbSNP
rs1310051999 1042 dbSNP
rs1229098792 1046 dbSNP
rs1327500094 1051 dbSNP
rs1482405546 1052 dbSNP
rs916883130 1055 dbSNP
rs1029897980 1070 dbSNP
rs1490472511 1075 dbSNP
rs1190377124 1076 dbSNP
rs1424781721 1077 dbSNP
rs975426429 1080 dbSNP
rs991648724 1081 dbSNP
rs1390869012 1085 dbSNP
rs1429120452 1087 dbSNP
rs1428138753 1088 dbSNP
rs1306783354 1098 dbSNP
rs1367969310 1100 dbSNP
rs1405988083 1105 dbSNP
rs964358447 1106 dbSNP
rs1365881629 1107 dbSNP
rs1033103627 1110 dbSNP
rs545150195 1113 dbSNP
rs576409707 1114 dbSNP
rs187149170 1118 dbSNP
rs1020062743 1122 dbSNP
rs374984899 1124 dbSNP
rs536539106 1130 dbSNP
rs895755324 1133 dbSNP
rs115999571 1137 dbSNP
rs537198768 1139 dbSNP
rs761684761 1141 dbSNP
rs898787643 1147 dbSNP
rs1242798802 1148 dbSNP
rs147371444 1150 dbSNP
rs940425954 1151 dbSNP
rs1387115538 1153 dbSNP
rs1280229537 1163 dbSNP
rs908737849 1164 dbSNP
rs1164613487 1167 dbSNP
rs1350512529 1182 dbSNP
rs1295789145 1186 dbSNP
rs1018237042 1187 dbSNP
rs1007300884 1190 dbSNP
rs1047242735 1192 dbSNP
rs893926506 1195 dbSNP
rs1316558365 1196 dbSNP
rs181761229 1206 dbSNP
rs999720790 1207 dbSNP
rs1288980133 1212 dbSNP
rs902662229 1223 dbSNP
rs975623966 1225 dbSNP
rs1318561972 1228 dbSNP
rs763223853 1231 dbSNP
rs1216232324 1236 dbSNP
rs964119007 1238 dbSNP
rs1312192212 1239 dbSNP
rs1046688608 1242 dbSNP
rs925940573 1243 dbSNP
rs552505153 1251 dbSNP
rs949574810 1269 dbSNP
rs895395940 1271 dbSNP
rs1055498587 1272 dbSNP
rs1160330817 1279 dbSNP
rs1388306535 1283 dbSNP
rs1455347575 1285 dbSNP
rs557686181 1290 dbSNP
rs1359251973 1294 dbSNP
rs1446637205 1296 dbSNP
rs1282425623 1299 dbSNP
rs1375402961 1315 dbSNP
rs1224222799 1319 dbSNP
rs1326728736 1323 dbSNP
rs1207070516 1338 dbSNP
rs1265216253 1339 dbSNP
rs909655795 1340 dbSNP
rs1020301123 1341 dbSNP
rs1428175756 1343 dbSNP
rs1236280009 1347 dbSNP
rs1420467100 1361 dbSNP
rs1183486468 1379 dbSNP
rs1014053572 1380 dbSNP
rs1471783057 1394 dbSNP
rs1178218355 1397 dbSNP
rs569906129 1400 dbSNP
rs1413451610 1413 dbSNP
rs1474265817 1423 dbSNP
rs959829857 1434 dbSNP
rs1410362134 1438 dbSNP
rs746033599 1441 dbSNP
rs1486914271 1443 dbSNP
rs1001855711 1446 dbSNP
rs929825114 1453 dbSNP
rs898865028 1456 dbSNP
rs1345946490 1457 dbSNP
rs550096567 1458 dbSNP
rs1276632803 1463 dbSNP
rs1004658312 1467 dbSNP
rs886204028 1471 dbSNP
rs530309912 1473 dbSNP
rs1295827144 1476 dbSNP
rs1215880891 1480 dbSNP
rs1202003820 1493 dbSNP
rs1353024355 1496 dbSNP
rs976641089 1500 dbSNP
rs373861178 1504 dbSNP
rs1018602282 1509 dbSNP
rs1421040787 1510 dbSNP
rs1429809489 1511 dbSNP
rs547736984 1516 dbSNP
rs1167954193 1517 dbSNP
rs527794189 1525 dbSNP
rs922763339 1527 dbSNP
rs1330262220 1530 dbSNP
rs1436037935 1532 dbSNP
rs1320074446 1534 dbSNP
rs958262626 1535 dbSNP
rs1296288387 1537 dbSNP
rs1032448162 1538 dbSNP
rs999575019 1539 dbSNP
rs1040015203 1546 dbSNP
rs902683217 1547 dbSNP
rs565336296 1548 dbSNP
rs1172816595 1558 dbSNP
rs1449581065 1560 dbSNP
rs112630956 1563 dbSNP
rs979190955 1565 dbSNP
rs1426511307 1566 dbSNP
rs1417279894 1568 dbSNP
rs1389768388 1569 dbSNP
rs1403380748 1570 dbSNP
rs946039008 1572 dbSNP
rs1367583006 1573 dbSNP
rs1435971842 1576 dbSNP
rs1188703193 1581 dbSNP
rs1296994335 1584 dbSNP
rs1363040323 1585 dbSNP
rs913325248 1586 dbSNP
rs1266531592 1590 dbSNP
rs1476498715 1597 dbSNP
rs1356169012 1607 dbSNP
rs1208397039 1608 dbSNP
rs1269680527 1608 dbSNP
rs576342702 1630 dbSNP
rs1249000830 1632 dbSNP
rs1207664307 1638 dbSNP
rs1055765940 1640 dbSNP
rs562655012 1641 dbSNP
rs542970111 1648 dbSNP
rs1367818132 1652 dbSNP
rs1471712300 1654 dbSNP
rs1253376799 1656 dbSNP
rs1048151387 1658 dbSNP
rs1389041961 1663 dbSNP
rs992831526 1665 dbSNP
rs1320071877 1669 dbSNP
rs1386617823 1673 dbSNP
rs11230730 1678 dbSNP
rs1314112253 1684 dbSNP
rs573954540 1687 dbSNP
rs1243187659 1688 dbSNP
rs1290627913 1691 dbSNP
rs566002129 1700 dbSNP
rs929689278 1706 dbSNP
rs1207732819 1710 dbSNP
rs1332152201 1722 dbSNP
rs918334006 1723 dbSNP
rs1200501668 1727 dbSNP
rs138264335 1732 dbSNP
rs1440653115 1734 dbSNP
rs1184207255 1742 dbSNP
rs1412452650 1752 dbSNP
rs1472134643 1764 dbSNP
rs1233330702 1774 dbSNP
rs1357353181 1776 dbSNP
rs533740176 1777 dbSNP
rs1467688759 1789 dbSNP
rs1303518816 1797 dbSNP
rs1390684123 1809 dbSNP
rs980071292 1818 dbSNP
rs911166229 1821 dbSNP
rs577667144 1824 dbSNP
rs985760599 1830 dbSNP
rs1351553983 1838 dbSNP
rs1228163219 1842 dbSNP
rs1286116902 1851 dbSNP
rs150889472 1856 dbSNP
rs1016157027 1862 dbSNP
rs758899369 1863 dbSNP
rs1004964305 1872 dbSNP
rs1165807166 1873 dbSNP
rs1342186908 1874 dbSNP
rs1207278869 1891 dbSNP
rs1252442824 1898 dbSNP
rs925233502 1922 dbSNP
rs1179718692 1926 dbSNP
rs886066841 1927 dbSNP
rs1030126471 1928 dbSNP
rs997261828 1933 dbSNP
rs978082552 1936 dbSNP
rs1464602418 1952 dbSNP
rs1053851301 1957 dbSNP
rs966817143 1959 dbSNP
rs935430907 1966 dbSNP
rs1025049122 1973 dbSNP
rs1013783545 1975 dbSNP
rs1040260013 1976 dbSNP
rs537531781 1980 dbSNP
rs536029271 1981 dbSNP
rs1306589805 1991 dbSNP
rs569944781 1997 dbSNP
rs1006850825 1998 dbSNP
rs550789669 2005 dbSNP
rs1370130998 2016 dbSNP
rs888122515 2023 dbSNP
rs570181485 2027 dbSNP
rs1309998545 2033 dbSNP
rs1043279103 2034 dbSNP
rs1275321708 2066 dbSNP
rs1048089817 2073 dbSNP
rs1341391828 2075 dbSNP
rs1192099095 2088 dbSNP
rs1202886061 2089 dbSNP
rs1466890152 2098 dbSNP
rs532575843 2099 dbSNP
rs866883610 2102 dbSNP
rs1488649814 2103 dbSNP
rs913230360 2104 dbSNP
rs1192057487 2107 dbSNP
rs1266942021 2114 dbSNP
rs1452705431 2123 dbSNP
rs896940175 2133 dbSNP
rs1190574017 2134 dbSNP
rs1390814273 2141 dbSNP
rs1040754398 2143 dbSNP
rs1429709497 2145 dbSNP
rs1168871885 2146 dbSNP
rs781378976 2146 dbSNP
rs1352039415 2150 dbSNP
rs2241001 2161 dbSNP
rs1292624150 2167 dbSNP
rs911020138 2172 dbSNP
rs1258372032 2174 dbSNP
rs1436762365 2177 dbSNP
rs1297730308 2180 dbSNP
rs1049666699 2184 dbSNP
rs980360263 2185 dbSNP
rs567910157 2189 dbSNP
rs1322179654 2192 dbSNP
rs1016598846 2197 dbSNP
rs547480193 2205 dbSNP
rs978115235 2210 dbSNP
rs1276847862 2211 dbSNP
rs1029992366 2215 dbSNP
rs778430882 2216 dbSNP
rs1448881071 2218 dbSNP
rs1185354013 2223 dbSNP
rs1231770443 2227 dbSNP
rs1416549889 2231 dbSNP
rs1424806606 2238 dbSNP
rs138992328 2240 dbSNP
rs527735504 2242 dbSNP
rs1392683562 2243 dbSNP
rs1458490084 2246 dbSNP
rs1326826299 2253 dbSNP
rs992214535 2266 dbSNP
rs1432263797 2267 dbSNP
rs1443298031 2269 dbSNP
rs1379781346 2282 dbSNP
rs530561334 2284 dbSNP
rs1288316181 2287 dbSNP
rs1034224129 2288 dbSNP
rs1330868963 2289 dbSNP
rs1454792583 2297 dbSNP
rs1006388119 2306 dbSNP
rs1007476012 2317 dbSNP
rs777824119 2318 dbSNP
rs952433072 2321 dbSNP
rs1454104364 2324 dbSNP
rs551883405 2334 dbSNP
rs1181718072 2342 dbSNP
rs562693516 2345 dbSNP
rs758709057 2351 dbSNP
rs1452922251 2359 dbSNP
rs891826255 2360 dbSNP
rs1057041415 2368 dbSNP
rs993819004 2374 dbSNP
rs1259091096 2375 dbSNP
rs145169218 2397 dbSNP
rs1040787250 2400 dbSNP
rs188500806 2401 dbSNP
rs1310936356 2405 dbSNP
rs1352166952 2407 dbSNP
rs889538460 2408 dbSNP
rs560348640 2415 dbSNP
rs909038897 2416 dbSNP
rs1346892544 2418 dbSNP
rs1312786287 2420 dbSNP
rs936502572 2421 dbSNP
rs565114907 2429 dbSNP
rs1256016050 2430 dbSNP
rs755883736 2432 dbSNP
rs1484265747 2436 dbSNP
rs983804697 2453 dbSNP
rs950597785 2455 dbSNP
rs540147323 2458 dbSNP
rs1425277438 2463 dbSNP
rs201841247 2463 dbSNP
rs1042304351 2464 dbSNP
rs1171762795 2467 dbSNP
rs1372304089 2470 dbSNP
rs1430273745 2479 dbSNP
rs1294998129 2489 dbSNP
rs977226242 2491 dbSNP
rs1382826169 2492 dbSNP
rs1333696395 2496 dbSNP
rs1440303164 2501 dbSNP
rs1363080825 2503 dbSNP
rs1311595536 2507 dbSNP
rs975761369 2508 dbSNP
rs1278876621 2509 dbSNP
rs1344970694 2513 dbSNP
rs945372451 2521 dbSNP
rs1434581499 2522 dbSNP
rs1274377770 2525 dbSNP
rs577602477 2543 dbSNP
rs964338659 2547 dbSNP
rs1200629528 2548 dbSNP
rs1246924531 2554 dbSNP
rs1477436666 2561 dbSNP
rs1191228706 2562 dbSNP
rs1391439380 2565 dbSNP
rs1430335873 2567 dbSNP
rs1167817268 2577 dbSNP
rs750199175 2578 dbSNP
rs1175874547 2585 dbSNP
rs1478827182 2591 dbSNP
rs1325819919 2598 dbSNP
rs551369214 2601 dbSNP
rs1000615413 2611 dbSNP
rs1367367179 2627 dbSNP
rs1191915138 2629 dbSNP
rs1270114356 2632 dbSNP
rs938134268 2647 dbSNP
rs1337936514 2652 dbSNP
rs1211972533 2661 dbSNP
rs1290974561 2663 dbSNP
rs184224343 2671 dbSNP
rs1211362579 2681 dbSNP
rs985394202 2688 dbSNP
rs952229452 2694 dbSNP
rs1485277530 2695 dbSNP
rs1010467969 2696 dbSNP
rs1473685514 2704 dbSNP
rs892064340 2714 dbSNP
rs1461127975 2715 dbSNP
rs1324066547 2735 dbSNP
rs1201933731 2736 dbSNP
rs1057286564 2737 dbSNP
rs1318294067 2748 dbSNP
rs1250956868 2749 dbSNP
rs1002832541 2750 dbSNP
rs141187033 2755 dbSNP
rs1228343055 2756 dbSNP
rs1044909564 2762 dbSNP
rs1026544252 2780 dbSNP
rs909064807 2781 dbSNP
rs972262207 2786 dbSNP
rs1464986714 2788 dbSNP
rs1204010035 2791 dbSNP
rs536076377 2792 dbSNP
rs961039886 2796 dbSNP
rs1047615671 2808 dbSNP
rs376084539 2811 dbSNP
rs1019276928 2822 dbSNP
rs1367696242 2822 dbSNP
rs1414743708 2829 dbSNP
rs868423956 2834 dbSNP
rs1356622759 2840 dbSNP
rs1007883784 2841 dbSNP
rs574960974 2843 dbSNP
rs556350593 2847 dbSNP
rs923193243 2848 dbSNP
rs975956276 2852 dbSNP
rs56374633 2854 dbSNP
rs1028052381 2855 dbSNP
rs372626255 2856 dbSNP
rs910209801 2859 dbSNP
rs536403468 2863 dbSNP
rs180798151 2873 dbSNP
rs945236303 2881 dbSNP
rs896401543 2882 dbSNP
rs1258111234 2890 dbSNP
rs764156712 2900 dbSNP
rs1329463397 2910 dbSNP
rs1237834010 2914 dbSNP
rs1258441053 2926 dbSNP
rs1056902364 2928 dbSNP
rs938014837 2929 dbSNP
rs747869235 2935 dbSNP
rs1484592281 2940 dbSNP
rs376630417 2941 dbSNP
rs775970602 2942 dbSNP
rs1010373188 2943 dbSNP
rs1196624493 2943 dbSNP
rs930828079 2952 dbSNP
rs1362192516 2956 dbSNP
rs919394474 2957 dbSNP
rs138241672 2964 dbSNP
rs1271389764 2966 dbSNP
rs966298532 2969 dbSNP
rs1375346875 2971 dbSNP
rs1019139830 2974 dbSNP
rs1046535 2983 dbSNP
rs1351419131 2989 dbSNP
rs1336180926 2994 dbSNP
rs1390480342 3001 dbSNP
rs750384793 3002 dbSNP
rs986893797 3011 dbSNP
rs1332387381 3012 dbSNP
rs1440567772 3012 dbSNP
rs1233302252 3014 dbSNP
rs776740336 3017 dbSNP
rs80128436 3018 dbSNP
rs1207126864 3020 dbSNP
rs1275105312 3026 dbSNP
rs1480179210 3030 dbSNP
rs887882345 3035 dbSNP
rs573778475 3036 dbSNP
rs1401987350 3045 dbSNP
rs1248646634 3050 dbSNP
rs1435026339 3052 dbSNP
rs1162233826 3060 dbSNP
rs1000585952 3063 dbSNP
rs1414531581 3079 dbSNP
rs903691524 3081 dbSNP
rs1164945806 3086 dbSNP
rs1468492692 3091 dbSNP
rs929125598 3096 dbSNP
rs143700921 3097 dbSNP
rs1046551 3100 dbSNP
rs1298237915 3105 dbSNP
rs911777504 3107 dbSNP
rs1040347090 3109 dbSNP
rs1266935216 3114 dbSNP
rs1204442440 3116 dbSNP
rs1489605291 3117 dbSNP
rs551769680 3118 dbSNP
rs1252468948 3119 dbSNP
rs34577470 3119 dbSNP
rs374692557 3119 dbSNP
rs531856149 3119 dbSNP
rs563379231 3119 dbSNP
rs66512613 3119 dbSNP
rs72516017 3119 dbSNP
rs1168804981 3120 dbSNP
rs910233909 3120 dbSNP
rs1370525353 3121 dbSNP
rs979139062 3123 dbSNP
rs1324786915 3125 dbSNP
rs1292050056 3127 dbSNP
rs1222587235 3128 dbSNP
rs1321190524 3136 dbSNP
rs946345446 3141 dbSNP
rs986485269 3141 dbSNP
rs188382827 3147 dbSNP
rs1242741951 3149 dbSNP
rs878962143 3152 dbSNP
rs1272782726 3153 dbSNP
rs1323475300 3153 dbSNP
rs1467228951 3156 dbSNP
rs1210647152 3158 dbSNP
rs987848971 3164 dbSNP
rs1185228269 3165 dbSNP
rs144928084 3165 dbSNP
rs1459427774 3165 dbSNP
rs1475736669 3165 dbSNP
rs796993547 3165 dbSNP
rs1163811393 3166 dbSNP
rs1415176054 3167 dbSNP
rs1458439849 3171 dbSNP
rs1159231153 3175 dbSNP
rs956243192 3176 dbSNP
rs569331705 3179 dbSNP
rs185532680 3181 dbSNP
rs1428570386 3182 dbSNP
rs982124848 3186 dbSNP
rs577665645 3207 dbSNP
rs1009396375 3208 dbSNP
rs1413913536 3209 dbSNP
rs1292960219 3217 dbSNP
rs1398920476 3220 dbSNP
rs773517956 3235 dbSNP
rs1023611861 3242 dbSNP
rs1006231205 3243 dbSNP
rs1056367130 3253 dbSNP
rs1026438368 3264 dbSNP
rs115815714 3279 dbSNP
rs905165035 3284 dbSNP
rs1255798881 3290 dbSNP
rs1193262087 3300 dbSNP
rs868389051 3301 dbSNP
rs560073559 3303 dbSNP
rs1248562961 3304 dbSNP
rs1213697445 3315 dbSNP
rs1398449054 3316 dbSNP
rs1178191646 3319 dbSNP
rs1446983590 3320 dbSNP
rs540549213 3324 dbSNP
rs533050778 3326 dbSNP
rs1040210706 3329 dbSNP
rs564126083 3334 dbSNP
rs748623738 3335 dbSNP
rs1444706719 3339 dbSNP
rs543767180 3341 dbSNP
rs889051580 3343 dbSNP
rs1222117409 3346 dbSNP
rs1233150860 3350 dbSNP
rs1044001510 3364 dbSNP
rs1210710765 3365 dbSNP
rs1278648711 3366 dbSNP
rs946405243 3367 dbSNP
rs919331884 3372 dbSNP
rs1367828433 3380 dbSNP
rs1036515314 3383 dbSNP
rs1468199746 3396 dbSNP
rs913562936 3397 dbSNP
rs12290716 3400 dbSNP
rs1171621490 3401 dbSNP
rs1453732271 3401 dbSNP
rs939086437 3403 dbSNP
rs912147607 3404 dbSNP
rs1329846747 3413 dbSNP
rs1354183165 3415 dbSNP
rs1440241734 3421 dbSNP
rs1305723690 3425 dbSNP
rs1371743856 3428 dbSNP
rs986369725 3428 dbSNP
rs953851074 3433 dbSNP
rs555092210 3443 dbSNP
rs979089354 3447 dbSNP
rs1421381774 3455 dbSNP
rs967823860 3457 dbSNP
rs981649739 3462 dbSNP
rs1172742806 3466 dbSNP
rs113393571 3467 dbSNP
rs1435753113 3476 dbSNP
rs779285519 3479 dbSNP
rs960505953 3482 dbSNP
rs1253100789 3485 dbSNP
rs1184917842 3487 dbSNP
rs1467634856 3493 dbSNP
rs574208646 3500 dbSNP
rs952057741 3507 dbSNP
rs1475670109 3508 dbSNP
rs1263914563 3512 dbSNP
rs1002095405 3513 dbSNP
rs1026303065 3515 dbSNP
rs1417044019 3516 dbSNP
rs1408441852 3531 dbSNP
rs1328152826 3537 dbSNP
rs1196494742 3541 dbSNP
rs993603011 3546 dbSNP
rs905196818 3552 dbSNP
rs1484954047 3553 dbSNP
rs901946733 3558 dbSNP
rs554048254 3568 dbSNP
rs994781439 3577 dbSNP
rs1328732335 3579 dbSNP
rs1432065930 3582 dbSNP
rs1269987462 3589 dbSNP
rs3741260 3595 dbSNP
rs1234815446 3600 dbSNP
rs35226310 3603 dbSNP
rs571812095 3605 dbSNP
rs748788761 3613 dbSNP
rs888906510 3624 dbSNP
rs558191028 3628 dbSNP
rs779755300 3629 dbSNP
rs1043683195 3652 dbSNP
rs538195267 3656 dbSNP
rs1212363608 3664 dbSNP
rs1192307661 3672 dbSNP
rs569270986 3682 dbSNP
rs1473652173 3693 dbSNP
rs1167425233 3694 dbSNP
rs1278227253 3697 dbSNP
rs762708686 3698 dbSNP
rs1162922518 3699 dbSNP
rs1387148926 3702 dbSNP
rs1353453902 3709 dbSNP
rs1312107278 3711 dbSNP
rs1318234047 3727 dbSNP
rs1325086784 3728 dbSNP
rs1466349902 3732 dbSNP
rs878888025 3732 dbSNP
rs1416983485 3735 dbSNP
rs1361189269 3738 dbSNP
rs892155460 3744 dbSNP
rs193293017 3745 dbSNP
rs1231004431 3746 dbSNP
rs3741259 3749 dbSNP
rs1350748530 3767 dbSNP
rs1204553293 3769 dbSNP
rs566682000 3771 dbSNP
rs1282031537 3773 dbSNP
rs926189334 3775 dbSNP
rs372123269 3788 dbSNP
rs1172867837 3789 dbSNP
rs767272902 3793 dbSNP
rs1475008552 3807 dbSNP
rs938993382 3814 dbSNP
rs533267535 3817 dbSNP
rs563994356 3818 dbSNP
rs1383462871 3820 dbSNP
rs1182871110 3831 dbSNP
rs913665623 3832 dbSNP
rs1313871464 3839 dbSNP
rs1375159192 3840 dbSNP
rs948956031 3843 dbSNP
rs987863935 3846 dbSNP
rs960823965 3851 dbSNP
rs1335874338 3856 dbSNP
rs952253256 3858 dbSNP
rs1277216707 3864 dbSNP
rs919483649 3870 dbSNP
rs544100094 3877 dbSNP
rs1302495319 3878 dbSNP
rs1211430110 3879 dbSNP
rs1279364185 3883 dbSNP
rs1484561654 3884 dbSNP
rs1002436531 3886 dbSNP
rs966000524 3893 dbSNP
rs555617081 3902 dbSNP
rs1019030235 3908 dbSNP
rs1181215108 3911 dbSNP
rs535818420 3912 dbSNP
rs1362064777 3913 dbSNP
rs1455977942 3921 dbSNP
rs1219915002 3922 dbSNP
rs1174799719 3924 dbSNP
rs1375292585 3928 dbSNP
rs1433212742 3946 dbSNP
rs530467406 3948 dbSNP
rs751427164 3953 dbSNP
rs1396797193 3958 dbSNP
rs1390422387 3966 dbSNP
rs1326286869 3969 dbSNP
rs1372471882 3977 dbSNP
rs1034645609 3978 dbSNP
rs1235008463 3980 dbSNP
rs1302583451 3981 dbSNP
rs1292597087 3982 dbSNP
rs953267511 3984 dbSNP
rs1229364704 3985 dbSNP
rs1381092026 3986 dbSNP
rs1027974138 3995 dbSNP
rs1481082391 4010 dbSNP
rs1195383229 4020 dbSNP
rs1236492962 4023 dbSNP
rs1296198437 4035 dbSNP
rs1441804962 4042 dbSNP
rs1431895855 4044 dbSNP
rs1173032699 4046 dbSNP
rs765727180 4052 dbSNP
rs994813180 4053 dbSNP
rs1165783033 4059 dbSNP
rs544040251 4060 dbSNP
rs1172982128 4063 dbSNP
rs1459934130 4075 dbSNP
rs1010671140 4077 dbSNP
rs561335368 4083 dbSNP
rs541939397 4086 dbSNP
rs1296038714 4093 dbSNP
rs892397055 4101 dbSNP
rs1227053332 4105 dbSNP
rs760069956 4117 dbSNP
rs1014966558 4118 dbSNP
rs1003167234 4120 dbSNP
rs1214422326 4123 dbSNP
rs1252412512 4126 dbSNP
rs906207510 4127 dbSNP
rs1188746384 4130 dbSNP
rs572825349 4136 dbSNP
rs1008903416 4137 dbSNP
rs1044853350 4142 dbSNP
rs947781084 4148 dbSNP
rs916102655 4151 dbSNP
rs1163586378 4154 dbSNP
rs1347549290 4160 dbSNP
rs1455332581 4176 dbSNP
rs1049711843 4177 dbSNP
rs930768884 4178 dbSNP
rs560755018 4184 dbSNP
rs1294844398 4190 dbSNP
rs540433019 4191 dbSNP
rs12276221 4192 dbSNP
rs1272643723 4197 dbSNP
rs1319991624 4200 dbSNP
rs1218649430 4208 dbSNP
rs904801722 4209 dbSNP
rs1261797398 4224 dbSNP
rs1485775939 4227 dbSNP
rs1191987024 4228 dbSNP
rs1043300475 4231 dbSNP
rs966073474 4232 dbSNP
rs1186761897 4234 dbSNP
rs911868858 4237 dbSNP
rs1420321661 4238 dbSNP
rs1159803546 4245 dbSNP
rs1240470547 4247 dbSNP
rs576756115 4247 dbSNP
rs1245459985 4252 dbSNP
rs1375773611 4264 dbSNP
rs1323398045 4277 dbSNP
rs1415688076 4278 dbSNP
rs986256918 4283 dbSNP
rs771505394 4284 dbSNP
rs1304662813 4285 dbSNP
rs913529728 4287 dbSNP
rs1222981782 4293 dbSNP
rs953605957 4297 dbSNP
rs1486199227 4299 dbSNP
rs1022350738 4313 dbSNP
rs1010703864 4314 dbSNP
rs956502434 4315 dbSNP
rs1406523423 4328 dbSNP
rs1437763731 4335 dbSNP
rs12808337 4336 dbSNP
rs1433836434 4336 dbSNP
rs538529270 4339 dbSNP
rs1294144637 4350 dbSNP
rs1444546065 4355 dbSNP
rs1003409811 4357 dbSNP
rs1343928913 4361 dbSNP
rs1158914812 4363 dbSNP
rs1238692074 4364 dbSNP
rs1306227062 4374 dbSNP
rs1349109175 4378 dbSNP
rs1234049283 4381 dbSNP
rs1276898103 4388 dbSNP
rs1439199098 4389 dbSNP
rs753876074 4392 dbSNP
rs766470061 4394 dbSNP
rs927698628 4395 dbSNP
rs1195470199 4396 dbSNP
rs1023701867 4408 dbSNP
rs188811304 4409 dbSNP
rs1266101101 4410 dbSNP
rs1209887691 4419 dbSNP
rs980661028 4431 dbSNP
rs555769372 4434 dbSNP
rs969601432 4443 dbSNP
rs1258888172 4453 dbSNP
rs1411918539 4454 dbSNP
rs1048108870 4457 dbSNP
rs1171389606 4459 dbSNP
rs535959357 4477 dbSNP
rs375360893 4478 dbSNP
rs961748457 4478 dbSNP
rs1232405720 4480 dbSNP
rs1014630089 4484 dbSNP
rs897992605 4486 dbSNP
rs1302133486 4488 dbSNP
rs1436302833 4494 dbSNP
rs1388583414 4496 dbSNP
rs1003681436 4499 dbSNP
rs973256095 4500 dbSNP
rs1298701402 4503 dbSNP
rs962027127 4507 dbSNP
rs1383524858 4509 dbSNP
rs1288801174 4519 dbSNP
rs185090253 4524 dbSNP
rs1271814794 4533 dbSNP
rs1362871822 4534 dbSNP
rs1009311028 4535 dbSNP
rs147632471 4537 dbSNP
rs890568164 4539 dbSNP
rs1432532308 4541 dbSNP
rs1029478736 4542 dbSNP
rs74438395 4548 dbSNP
rs904665040 4559 dbSNP
rs1475599547 4561 dbSNP
rs1434400096 4563 dbSNP
rs1258981974 4565 dbSNP
rs114587053 4566 dbSNP
rs931968282 4568 dbSNP
rs1395237862 4570 dbSNP
rs1405355336 4576 dbSNP
rs71490328 4580 dbSNP
rs762073340 4586 dbSNP
rs1328602291 4587 dbSNP
rs989522593 4587 dbSNP
rs892042835 4588 dbSNP
rs1338012788 4591 dbSNP
rs1234678650 4601 dbSNP
rs11545616 4603 dbSNP
rs200482664 4615 dbSNP
rs866962247 4615 dbSNP
rs1355025654 4617 dbSNP
rs139433433 4618 dbSNP
rs1214842941 4619 dbSNP
rs939004046 4622 dbSNP
rs1256809160 4623 dbSNP
rs971069188 4624 dbSNP
rs1012333749 4625 dbSNP
rs1023522098 4625 dbSNP
rs769017106 4625 dbSNP
rs1235607472 4626 dbSNP
rs927750465 4630 dbSNP
rs1026775286 4631 dbSNP
rs993909341 4633 dbSNP
rs1242009206 4643 dbSNP
rs1401179210 4648 dbSNP
rs980908311 4651 dbSNP
rs1351315723 4653 dbSNP
rs898020403 4662 dbSNP
rs530696037 4663 dbSNP
rs944864983 4668 dbSNP
rs2924439 4669 dbSNP
rs1257099707 4677 dbSNP
rs973203985 4678 dbSNP
rs1365545362 4679 dbSNP
rs1394105274 4684 dbSNP
rs932016216 4685 dbSNP
rs547844920 4686 dbSNP
rs779649167 4687 dbSNP
rs1401090672 4688 dbSNP
rs757898493 4688 dbSNP
rs769430595 4692 dbSNP
rs987518349 4694 dbSNP
rs954844077 4695 dbSNP
rs1335819051 4702 dbSNP
rs1467214120 4708 dbSNP
rs551536634 4710 dbSNP
rs1239421948 4715 dbSNP
rs528072499 4719 dbSNP
rs1169302251 4720 dbSNP
rs996624593 4722 dbSNP
rs1478137117 4723 dbSNP
rs1057544 4726 dbSNP
rs981922301 4728 dbSNP
rs755883929 4732 dbSNP
rs545881695 4733 dbSNP
rs745704116 4735 dbSNP
rs777655094 4736 dbSNP
rs1441641410 4739 dbSNP
rs1396644552 4742 dbSNP
rs1445376822 4751 dbSNP
rs1057498144 4752 dbSNP
rs1202421397 4755 dbSNP
rs1003230571 4759 dbSNP
rs578235219 4761 dbSNP
rs1044830523 4762 dbSNP
rs947830754 4766 dbSNP
rs1300352259 4769 dbSNP
rs1329128056 4770 dbSNP
rs1023975002 4774 dbSNP
rs920343303 4775 dbSNP
rs990748526 4775 dbSNP
rs1198121302 4778 dbSNP
rs758283267 4781 dbSNP
rs1291984009 4782 dbSNP
rs940514965 4796 dbSNP
rs549253689 4797 dbSNP
rs1431773584 4798 dbSNP
rs1026637870 4801 dbSNP
rs111604971 4807 dbSNP
rs961129662 4808 dbSNP
rs1397644444 4809 dbSNP
rs1057547 4812 dbSNP
rs1009483917 4813 dbSNP
rs954735509 4815 dbSNP
rs760741608 4817 dbSNP
rs1383724979 4832 dbSNP
rs1051152926 4840 dbSNP
rs575974218 4845 dbSNP
rs996431392 4850 dbSNP
rs1162720800 4853 dbSNP
rs186885580 4859 dbSNP
rs1337034865 4868 dbSNP
rs968827640 4871 dbSNP
rs1021697820 4874 dbSNP
rs1368867290 4875 dbSNP
rs1487764134 4876 dbSNP
rs1207294417 4878 dbSNP
rs1189323762 4881 dbSNP
rs1010424997 4884 dbSNP
rs956170644 4894 dbSNP
rs935303988 4895 dbSNP
rs1035951047 4909 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aacaggugaagaagGACGGGAc 5'
                        ||||||| 
Target 5' --------------CUGCCCUu 3'
 		1 - 8
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177621. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_3_11 PAR-CLIP data was present in ERX177609. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_2_11 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000263846.4 | 3UTR | CUGCCCUUCCUCAUCUCUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
87 hsa-miR-4436b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066957 ATXN7L3B ataxin 7 like 3B 2 8
MIRT119284 NABP1 nucleic acid binding protein 1 2 6
MIRT128915 KMT2A lysine methyltransferase 2A 2 2
MIRT150116 MIDN midnolin 2 2
MIRT173040 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT253117 BCL2L12 BCL2 like 12 2 2
MIRT256997 RGMB repulsive guidance molecule family member b 2 2
MIRT259746 SNX12 sorting nexin 12 2 2
MIRT267278 TMEM109 transmembrane protein 109 2 2
MIRT441934 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT443625 CPSF2 cleavage and polyadenylation specific factor 2 2 2
MIRT445757 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT447835 CTIF cap binding complex dependent translation initiation factor 2 2
MIRT451230 ZNF444 zinc finger protein 444 2 2
MIRT451966 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT453127 HOXC4 homeobox C4 2 2
MIRT454604 RPL13A ribosomal protein L13a 2 2
MIRT455176 SUV39H1 suppressor of variegation 3-9 homolog 1 2 2
MIRT455547 GJB1 gap junction protein beta 1 2 2
MIRT458197 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT458356 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458923 DNM2 dynamin 2 2 2
MIRT461013 SYT7 synaptotagmin 7 2 2
MIRT461643 ZSWIM4 zinc finger SWIM-type containing 4 2 2
MIRT461997 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT462367 BCL7B BCL tumor suppressor 7B 2 2
MIRT464915 TXNIP thioredoxin interacting protein 2 2
MIRT466311 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466591 TBC1D2B TBC1 domain family member 2B 2 2
MIRT467045 SRSF1 serine and arginine rich splicing factor 1 2 2
MIRT468750 SDC2 syndecan 2 2 2
MIRT468943 RPS24 ribosomal protein S24 2 2
MIRT469474 REEP5 receptor accessory protein 5 2 2
MIRT469913 PTRF caveolae associated protein 1 2 2
MIRT473325 MEX3A mex-3 RNA binding family member A 2 2
MIRT473643 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474064 LMNB2 lamin B2 2 2
MIRT474357 KMT2D lysine methyltransferase 2D 2 2
MIRT475394 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT476335 GLTSCR1L BRD4 interacting chromatin remodeling complex associated protein like 2 2
MIRT478651 CTDNEP1 CTD nuclear envelope phosphatase 1 2 2
MIRT479585 CDC42SE1 CDC42 small effector 1 2 2
MIRT479943 CBX5 chromobox 5 2 2
MIRT482001 AMOTL2 angiomotin like 2 2 2
MIRT482043 AMER1 APC membrane recruitment protein 1 2 2
MIRT483070 EXT2 exostosin glycosyltransferase 2 2 6
MIRT484323 KCNH1 potassium voltage-gated channel subfamily H member 1 2 4
MIRT487528 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT489636 ALS2CL ALS2 C-terminal like 2 2
MIRT490693 SSTR1 somatostatin receptor 1 2 2
MIRT490871 UPK2 uroplakin 2 2 2
MIRT492582 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT492945 NEUROD2 neuronal differentiation 2 2 2
MIRT498675 SOD2 superoxide dismutase 2 2 4
MIRT499349 RAB25 RAB25, member RAS oncogene family 2 2
MIRT502338 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT502976 CCNL1 cyclin L1 2 8
MIRT503706 NUP62 nucleoporin 62 2 2
MIRT505567 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2 2
MIRT507808 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT513242 FBXO41 F-box protein 41 2 6
MIRT513586 EVX1 even-skipped homeobox 1 2 2
MIRT525036 FRK fyn related Src family tyrosine kinase 2 2
MIRT531035 TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 2 2
MIRT531939 RBMS2 RNA binding motif single stranded interacting protein 2 2 2
MIRT534912 PUM2 pumilio RNA binding family member 2 2 2
MIRT535717 N4BP1 NEDD4 binding protein 1 2 2
MIRT540498 ZMAT4 zinc finger matrin-type 4 2 4
MIRT541465 AURKA aurora kinase A 2 2
MIRT554328 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT561572 SLC6A9 solute carrier family 6 member 9 2 2
MIRT564715 ZNF322P1 zinc finger protein 322 pseudogene 1 2 2
MIRT576176 Hmox1 heme oxygenase 1 2 2
MIRT629712 XKR4 XK related 4 2 2
MIRT636182 THBD thrombomodulin 2 2
MIRT646315 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT649174 IQSEC1 IQ motif and Sec7 domain 1 2 2
MIRT666945 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT684057 FOLR1 folate receptor 1 2 2
MIRT687585 MAU2 MAU2 sister chromatid cohesion factor 2 2
MIRT689953 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT704071 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT704327 DCUN1D5 defective in cullin neddylation 1 domain containing 5 2 2
MIRT705406 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 2 2
MIRT710488 CDH5 cadherin 5 2 2
MIRT718241 LCE1A late cornified envelope 1A 2 2
MIRT723182 CDCA4 cell division cycle associated 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4436b-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4436b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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