miRTarBase - #MIRT461464


—
pre-miRNA Information
pre-miRNA hsa-mir-4745   
Genomic Coordinates chr19: 804940 - 805001
Description Homo sapiens miR-4745 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4745-5p
Sequence 2| UGAGUGGGGCUCCCGGGACGGCG |24
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM6231418 6 COSMIC
COSN9853232 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1383282684 5 dbSNP
rs1397680926 5 dbSNP
rs569478349 7 dbSNP
rs1370492118 8 dbSNP
rs773676198 9 dbSNP
rs1163342742 10 dbSNP
rs1364058972 13 dbSNP
rs374562787 14 dbSNP
rs771228280 15 dbSNP
rs10422347 19 dbSNP
rs759808148 20 dbSNP
rs765171167 21 dbSNP
rs147466582 22 dbSNP
rs139864698 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC19A3   
Synonyms BBGD, THMD2, THTR2
Description solute carrier family 19 member 3
Transcript NM_025243   
Expression
Putative miRNA Targets on SLC19A3
3'UTR of SLC19A3
(miRNA target sites are highlighted)		 
>SLC19A3|NM_025243|3'UTR
   1 CCTCATCGCAACAAACGCAACAGTGGCTTTCAAAGTTATGCAATAATAAGGAAAGATTTTGAGATGGGTGGCATATGTTT
  81 TGCCATAACTTGACATGCTTTGCAAATCTGGATTCCAATGGACCTTTCAAAACCACAACAAAACCTCAGTTTTAGATGAG
 161 TTCTCTATGTGACCAATTTTACTGGATGCAATTGACAGGACCCGTCATCATAATTAAACAACCCATATTGGGGACCCCCT
 241 GTGACTAGTAGCAGCTGGAAAATTCTGGTTTTTATCACTTGTAAAGACATGCAGATGGCGTGGAACCAAACCATGAGAAA
 321 ACTCCAGCCATCCTGGAGTTGATATTCACCATTTGTGAGGAGAAATACTAACTGGACTGACCCTATTGCTAGGCTTAAAT
 401 ACTTATTTGATCTTACCAAAGAAGTCAACACATGGGACCTTTGTGTCACATGAACCATTTTCTTTCCTCTTCTATTAAGT
 481 GTATTTCTGTTTAAGTTACAGTTCTCTAAGAGAATTACAATGTTTGTCCCATTTCTAAGGGCTTCTCTTCAACTCTAATA
 561 ACAGCATTATTCACGTTATGATTTGATAGTATTATTATTTAATTTTTTTATGATTATTTTCCATTTTGTGCTCTGAGTTT
 641 TGCTGTTGAAAGTCTCCCTCAAGAATAGCTTCAGATCCTCTTGTGTATTTGCAGAATACACAAGGTCATTTCCCAGTGGC
 721 CTGGGAGAGGCAGTGAGCCTTCTCTCCACCACCATAGACAGGTGTTAATGCATCTATGGGCCAGGTGCAGTGGCTCACTC
 801 CTGTAATCCGAGCAATTTGGGAGGCCAAGGTGGGAGTTTTGCTTGAGGCCAGAGGTTCAAGACCAGCCTGGGCAACACAG
 881 TGACACCTGACTCTACTAAAAAATTAAAAAATTAGCTGGGCAGCGTGGTGTGTGCCTGTAGTCTCAGCTACTTGGGAGGC
 961 CATGGTGGGAGGATGGGTTGAGCACAGGAGTCAGAGGCTACAGTGAGCTATGATTGCACCATTGCACTCCAGCCTGGGCA
1041 ACAGAGTAAGACTCTCATCCCCCTCCTCCCAAAAAAGAGCACCTGTGTGGTGTCTGTCTAAAATAGGAAAACTTAAAGGA
1121 GGTTTCTAGAAGTATTAGAAATAAGAAAACACTGATGGGGGGAGTGGAATAAAACACCTGATTTTGTTTTGTTTTGGTTT
1201 TTGAGACAGTCTCGCTCTCTCACCCAGGCTGGAATGCAATGGCGTGATCTTGGCTCACTGCAAACTTCACCTCCTGAGTT
1281 CAAGCCATTCTCCTACCTCAGCCTCCCAAGTAGCTGGGACTATGGGTGCACACCACCACGCCTGGCTAATTTTTGTATTT
1361 TTAGTGGAGATGGGGTTTCACAATGTTGGCCAGGCTGGTCTCAAACTCCTGACTTCAGGTGATCTGTCTGCCTCGGCCTC
1441 CCAAAGAGCTGAGATTACAGGCGTGAGCCACCATGCCTGGCCAAAACACCTGATTTTTAAATGGTAGCAATTGTGCTAAA
1521 TAAAATGTGTAAAAATTTTAAAGAGTTGTTAACATTTTTTGATGAATTCTGCTGAAAATTATCTGAACATACCTGTTTTT
1601 CGAAACTTCAAGAAACTTCAATAAGGGATGCATTGAGCAGTCTGACAGTGAGAATAAAGAATGCTGAGTCAAGATTTATA
1681 TTAAGGCTGGAAGCTGTGGCTCACACCTGTAATCCCAGCATTTTGGGAGGCTGAAGTGAGAGGTTAATTTGAGGGTAGGG
1761 GTATGAGACCATCTTGGCCAATATAGCAAGACCCTGTGTCTAAAACAAACAAAAAAATTTTTAATTGGATTTTGATATGG
1841 TTTGGATCTGTGTCCCCACCAAATCTCACGTTGAAGTGTAATCCCCAATGTTAGAGGTGGGGCCGGCTGGGAGGCGACTG
1921 GATCATGGGTGTGAAGCCTTCATGAATGGTTTGGCACCGTCCCCTCAGTGCTGGTCTCATGACAGTGAGTTATCGTGAGA
2001 TCTGGTAGTTTAAAAGTGTGTAGCACCTCCCCACTCTCTCTTTCTCCTGCTTTGGCCACGTGAAGATGCCTGCTCCCACT
2081 TTGCCTTCTGCCATGAGTAAAAATTCCCCGAGGACTCCCTAGAAGCAGATGTTGCCACGCTTCCTATATAGCCTGTGAGC
2161 TAATTAAACCCCTTTTCTTACAAACTAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gcggcagggcccucGGGGUGAGu 5'
                        |||||||| 
Target 5' agtgtgtagcacctCCCCACTCt 3'
 2015 - 2037 145.00 -18.60
2 
miRNA  3' gcggCAGGGCC----CUCGGGGUGAGu 5'
              | || ||    | | |:||||| 
Target 5' tatgGGCCAGGTGCAGTGGCTCACTCc 3'
 775 - 801 133.00 -15.00
3 
miRNA  3' gcGGCAGG-GCCCU--------CG-GGGUGAGu 5'
            ::| || || ||        || ||||||: 
Target 5' ctTTGGCCACGTGAAGATGCCTGCTCCCACTTt 3'
 2050 - 2082 127.00 -17.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
198267 8 ClinVar
805463 8 ClinVar
334876 33 ClinVar
897118 59 ClinVar
897117 103 ClinVar
334875 106 ClinVar
896656 115 ClinVar
334874 176 ClinVar
334873 203 ClinVar
334872 204 ClinVar
334871 231 ClinVar
896655 289 ClinVar
334870 300 ClinVar
334869 348 ClinVar
334868 499 ClinVar
334867 506 ClinVar
895228 570 ClinVar
334866 575 ClinVar
334865 600 ClinVar
334864 685 ClinVar
895227 713 ClinVar
334863 778 ClinVar
334862 803 ClinVar
899318 924 ClinVar
899317 975 ClinVar
334861 978 ClinVar
334860 1000 ClinVar
334859 1003 ClinVar
899316 1044 ClinVar
334858 1059 ClinVar
334857 1072 ClinVar
334856 1090 ClinVar
898213 1094 ClinVar
334855 1104 ClinVar
334854 1121 ClinVar
898212 1207 ClinVar
898211 1256 ClinVar
898210 1264 ClinVar
334853 1320 ClinVar
334852 1339 ClinVar
896584 1355 ClinVar
334851 1427 ClinVar
896583 1463 ClinVar
334850 1517 ClinVar
896582 1630 ClinVar
334849 1684 ClinVar
334848 1696 ClinVar
334847 1740 ClinVar
334846 1792 ClinVar
895165 1800 ClinVar
334845 1813 ClinVar
334844 1815 ClinVar
334843 1818 ClinVar
334842 1839 ClinVar
895164 1842 ClinVar
895163 1859 ClinVar
899260 1889 ClinVar
899259 1905 ClinVar
334841 1925 ClinVar
334840 1953 ClinVar
334839 1963 ClinVar
334838 1974 ClinVar
899258 1995 ClinVar
334837 1996 ClinVar
334836 2033 ClinVar
898158 2050 ClinVar
334835 2104 ClinVar
334834 2109 ClinVar
334833 2129 ClinVar
334832 2130 ClinVar
334830 2132 ClinVar
334831 2132 ClinVar
334829 2139 ClinVar
896536 2159 ClinVar
COSN26994942 7 COSMIC
COSN31536627 10 COSMIC
COSN31560359 16 COSMIC
COSN31571523 17 COSMIC
COSN30162082 22 COSMIC
COSN31551033 27 COSMIC
COSN30156805 45 COSMIC
COSN30153836 61 COSMIC
COSN30458542 69 COSMIC
COSN30535234 106 COSMIC
COSN31498781 120 COSMIC
COSN30170167 165 COSMIC
COSN31571056 198 COSMIC
COSN8608725 230 COSMIC
COSN20601663 834 COSMIC
COSN9995564 1043 COSMIC
COSN24953058 1128 COSMIC
COSN20090743 1132 COSMIC
COSN30661943 1190 COSMIC
COSN30548003 1198 COSMIC
COSN19702710 1223 COSMIC
COSN17037878 1243 COSMIC
COSN8558623 1497 COSMIC
COSN5865356 1767 COSMIC
COSN23418689 1818 COSMIC
COSN20159543 2072 COSMIC
COSN23063277 2224 COSMIC
COSN16745697 2288 COSMIC
COSN7237846 2715 COSMIC
COSN16610896 3047 COSMIC
COSN20621455 3213 COSMIC
COSN24371729 3278 COSMIC
COSN9995561 3527 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs763595744 2 dbSNP
rs377323228 5 dbSNP
rs975129916 7 dbSNP
rs188532608 8 dbSNP
rs1207458881 12 dbSNP
rs776907842 13 dbSNP
rs199499719 16 dbSNP
rs761295032 17 dbSNP
rs1359744569 18 dbSNP
rs371251177 25 dbSNP
rs749248666 32 dbSNP
rs886055763 33 dbSNP
rs1318392317 36 dbSNP
rs745399850 39 dbSNP
rs915952341 40 dbSNP
rs779771123 42 dbSNP
rs1297367593 44 dbSNP
rs755910828 45 dbSNP
rs1367717922 47 dbSNP
rs745730487 50 dbSNP
rs148873152 52 dbSNP
rs1245052994 57 dbSNP
rs991975369 59 dbSNP
rs1194630295 60 dbSNP
rs1003494762 61 dbSNP
rs562213489 62 dbSNP
rs1044966154 64 dbSNP
rs183992017 66 dbSNP
rs1405865561 67 dbSNP
rs1413903664 70 dbSNP
rs1328812644 76 dbSNP
rs898798043 78 dbSNP
rs1404000766 89 dbSNP
rs116590386 103 dbSNP
rs886055762 106 dbSNP
rs940444405 108 dbSNP
rs549546166 115 dbSNP
rs1217112564 121 dbSNP
rs1251254677 124 dbSNP
rs1051868414 132 dbSNP
rs138554855 139 dbSNP
rs1410795243 148 dbSNP
rs1287877180 154 dbSNP
rs570743421 171 dbSNP
rs1217666866 173 dbSNP
rs886055761 176 dbSNP
rs922195196 177 dbSNP
rs1210876339 178 dbSNP
rs1179632054 184 dbSNP
rs776336362 187 dbSNP
rs1478689922 196 dbSNP
rs890786407 202 dbSNP
rs80307329 203 dbSNP
rs560082192 204 dbSNP
rs914538926 207 dbSNP
rs1164901108 211 dbSNP
rs988934111 218 dbSNP
rs956100048 220 dbSNP
rs1030864059 223 dbSNP
rs1441203901 224 dbSNP
rs892892723 226 dbSNP
rs1298436030 227 dbSNP
rs1003396224 228 dbSNP
rs192321676 231 dbSNP
rs934479506 232 dbSNP
rs1295364351 233 dbSNP
rs1341425861 234 dbSNP
rs1204470065 235 dbSNP
rs567092282 236 dbSNP
rs1023981577 237 dbSNP
rs1247655466 240 dbSNP
rs1282907671 241 dbSNP
rs1358829120 243 dbSNP
rs1217362558 244 dbSNP
rs1288241389 246 dbSNP
rs924470002 252 dbSNP
rs1046056350 257 dbSNP
rs1442735429 262 dbSNP
rs114116140 266 dbSNP
rs769503014 269 dbSNP
rs1366576779 274 dbSNP
rs1443494319 280 dbSNP
rs898867925 290 dbSNP
rs1381595531 298 dbSNP
rs1417535840 299 dbSNP
rs886055760 300 dbSNP
rs1403400089 301 dbSNP
rs756936405 303 dbSNP
rs1398087509 308 dbSNP
rs1279984000 318 dbSNP
rs1332788574 326 dbSNP
rs150113016 327 dbSNP
rs1357388214 334 dbSNP
rs886169023 346 dbSNP
rs112957132 348 dbSNP
rs550609221 350 dbSNP
rs1351567199 351 dbSNP
rs1238627190 353 dbSNP
rs991508598 357 dbSNP
rs1256768681 372 dbSNP
rs1470233751 373 dbSNP
rs1387328281 377 dbSNP
rs1156306138 379 dbSNP
rs930690284 379 dbSNP
rs920691214 381 dbSNP
rs1241021780 382 dbSNP
rs1473400160 382 dbSNP
rs1460847402 383 dbSNP
rs1408184580 388 dbSNP
rs532167253 390 dbSNP
rs1239490155 391 dbSNP
rs1437235082 402 dbSNP
rs933496714 410 dbSNP
rs1181641793 415 dbSNP
rs1471993364 417 dbSNP
rs1239749079 418 dbSNP
rs1188915720 421 dbSNP
rs972171736 423 dbSNP
rs564704093 432 dbSNP
rs962186958 438 dbSNP
rs540561445 456 dbSNP
rs1333891782 467 dbSNP
rs1019151049 469 dbSNP
rs1266387930 472 dbSNP
rs1210657605 474 dbSNP
rs186786917 478 dbSNP
rs1231329572 490 dbSNP
rs1261077771 495 dbSNP
rs182183617 499 dbSNP
rs914609965 502 dbSNP
rs1199228776 503 dbSNP
rs115182620 506 dbSNP
rs1479382257 520 dbSNP
rs376998255 521 dbSNP
rs1176185016 524 dbSNP
rs1285699579 529 dbSNP
rs996537408 532 dbSNP
rs1434582613 550 dbSNP
rs1196806590 560 dbSNP
rs1429048089 563 dbSNP
rs1466428649 564 dbSNP
rs928718259 565 dbSNP
rs1364347505 569 dbSNP
rs1461906570 570 dbSNP
rs981491046 574 dbSNP
rs528139519 575 dbSNP
rs1458295320 576 dbSNP
rs575063804 586 dbSNP
rs1279848319 589 dbSNP
rs1345448819 597 dbSNP
rs539344508 600 dbSNP
rs1265564597 604 dbSNP
rs1489145559 606 dbSNP
rs903016067 609 dbSNP
rs1403225299 610 dbSNP
rs559432461 613 dbSNP
rs867900915 630 dbSNP
rs1184592630 631 dbSNP
rs755993321 634 dbSNP
rs1449452865 636 dbSNP
rs1246666765 640 dbSNP
rs949968676 652 dbSNP
rs991179711 663 dbSNP
rs1351721027 668 dbSNP
rs1456398841 668 dbSNP
rs1190601389 676 dbSNP
rs1361481302 681 dbSNP
rs1056171571 684 dbSNP
rs886055759 685 dbSNP
rs1279907180 687 dbSNP
rs1359573050 696 dbSNP
rs1465363021 699 dbSNP
rs147551063 704 dbSNP
rs1322999646 708 dbSNP
rs768535976 719 dbSNP
rs544280958 720 dbSNP
rs190208501 737 dbSNP
rs1488450045 738 dbSNP
rs1030044435 742 dbSNP
rs1240742435 744 dbSNP
rs997233344 757 dbSNP
rs558668615 762 dbSNP
rs940791207 768 dbSNP
rs900706386 775 dbSNP
rs752747494 776 dbSNP
rs746927619 777 dbSNP
rs886055758 778 dbSNP
rs1416517275 788 dbSNP
rs780080112 790 dbSNP
rs186279191 803 dbSNP
rs1421807785 804 dbSNP
rs987661954 805 dbSNP
rs953736749 809 dbSNP
rs767369250 810 dbSNP
rs1303367689 814 dbSNP
rs1053336464 817 dbSNP
rs1381321897 828 dbSNP
rs1436675928 830 dbSNP
rs1029231683 839 dbSNP
rs1362107015 840 dbSNP
rs1313787663 841 dbSNP
rs1353771894 847 dbSNP
rs1241912968 852 dbSNP
rs1281621380 863 dbSNP
rs1292408781 865 dbSNP
rs573410224 866 dbSNP
rs868464046 869 dbSNP
rs1239578042 876 dbSNP
rs989712084 879 dbSNP
rs1183497115 904 dbSNP
rs1238887406 913 dbSNP
rs1441574913 915 dbSNP
rs758502895 919 dbSNP
rs957030750 924 dbSNP
rs750560944 925 dbSNP
rs1468210851 928 dbSNP
rs878869298 932 dbSNP
rs1377003408 936 dbSNP
rs1032672143 938 dbSNP
rs998526152 941 dbSNP
rs1372251796 951 dbSNP
rs555222181 955 dbSNP
rs758124836 961 dbSNP
rs1321800047 963 dbSNP
rs374380155 968 dbSNP
rs1203617757 969 dbSNP
rs371001817 975 dbSNP
rs1179815268 978 dbSNP
rs569329913 978 dbSNP
rs1024535567 979 dbSNP
rs1388897631 987 dbSNP
rs1431189656 988 dbSNP
rs1467978396 991 dbSNP
rs1171090100 997 dbSNP
rs1401016826 998 dbSNP
rs796258373 999 dbSNP
rs111467219 1000 dbSNP
rs886055757 1003 dbSNP
rs1424631096 1004 dbSNP
rs550723545 1010 dbSNP
rs1284758319 1017 dbSNP
rs1344027264 1020 dbSNP
rs1055697328 1021 dbSNP
rs1279217192 1025 dbSNP
rs948825311 1038 dbSNP
rs865842645 1039 dbSNP
rs1189534699 1043 dbSNP
rs538351766 1052 dbSNP
rs930587284 1056 dbSNP
rs886055756 1059 dbSNP
rs1194552611 1064 dbSNP
rs1272440336 1069 dbSNP
rs916430976 1071 dbSNP
rs886055755 1072 dbSNP
rs778943257 1076 dbSNP
rs1269783146 1079 dbSNP
rs78560894 1090 dbSNP
rs111724178 1094 dbSNP
rs1198508519 1096 dbSNP
rs950388151 1097 dbSNP
rs183127958 1100 dbSNP
rs886055754 1104 dbSNP
rs1424038888 1111 dbSNP
rs1476381162 1119 dbSNP
rs539114374 1121 dbSNP
rs764583554 1124 dbSNP
rs997707593 1128 dbSNP
rs900236423 1130 dbSNP
rs1052308673 1131 dbSNP
rs1363391875 1134 dbSNP
rs1403943656 1136 dbSNP
rs764291121 1142 dbSNP
rs1011760451 1153 dbSNP
rs932149039 1157 dbSNP
rs1230574241 1158 dbSNP
rs1328539578 1160 dbSNP
rs1225907350 1161 dbSNP
rs1308005461 1163 dbSNP
rs1357159711 1167 dbSNP
rs1248338856 1178 dbSNP
rs922131599 1190 dbSNP
rs1444207589 1192 dbSNP
rs1373774791 1194 dbSNP
rs1195406225 1198 dbSNP
rs893274853 1200 dbSNP
rs1217599776 1205 dbSNP
rs1263662666 1206 dbSNP
rs1427276202 1207 dbSNP
rs1488610736 1213 dbSNP
rs142609990 1214 dbSNP
rs530648356 1216 dbSNP
rs1490955536 1219 dbSNP
rs1290016878 1220 dbSNP
rs1219870568 1222 dbSNP
rs1473076536 1225 dbSNP
rs1165002058 1226 dbSNP
rs1382817382 1227 dbSNP
rs1393558894 1236 dbSNP
rs756911054 1243 dbSNP
rs1045721246 1244 dbSNP
rs1228897463 1246 dbSNP
rs191669498 1256 dbSNP
rs1277440566 1257 dbSNP
rs1353654296 1259 dbSNP
rs1405449382 1262 dbSNP
rs553308770 1264 dbSNP
rs1301046013 1265 dbSNP
rs1405056039 1271 dbSNP
rs763533626 1272 dbSNP
rs967502720 1275 dbSNP
rs1024046010 1277 dbSNP
rs1400683380 1279 dbSNP
rs1460496267 1283 dbSNP
rs1422976403 1284 dbSNP
rs544734387 1287 dbSNP
rs577224617 1294 dbSNP
rs1038830607 1303 dbSNP
rs941873868 1317 dbSNP
rs1014444714 1319 dbSNP
rs536282437 1320 dbSNP
rs1461741768 1321 dbSNP
rs1185322158 1322 dbSNP
rs1240748024 1331 dbSNP
rs565281146 1335 dbSNP
rs540235103 1339 dbSNP
rs1178870202 1340 dbSNP
rs1365244139 1342 dbSNP
rs950628098 1345 dbSNP
rs994724494 1348 dbSNP
rs1247435862 1355 dbSNP
rs1447957006 1355 dbSNP
rs866083330 1364 dbSNP
rs868760872 1379 dbSNP
rs1197326006 1383 dbSNP
rs899086209 1389 dbSNP
rs1335272858 1394 dbSNP
rs776011729 1396 dbSNP
rs3208767 1417 dbSNP
rs1382138362 1418 dbSNP
rs12105610 1427 dbSNP
rs1309215445 1434 dbSNP
rs975756089 1435 dbSNP
rs1334269898 1443 dbSNP
rs1255271228 1449 dbSNP
rs1238559082 1462 dbSNP
rs555334820 1463 dbSNP
rs759804318 1466 dbSNP
rs1325010608 1472 dbSNP
rs1011703738 1475 dbSNP
rs1177348169 1480 dbSNP
rs1227472282 1482 dbSNP
rs1348225814 1486 dbSNP
rs1290611378 1494 dbSNP
rs957566199 1498 dbSNP
rs1031837451 1501 dbSNP
rs932091469 1504 dbSNP
rs536923932 1507 dbSNP
rs1406064477 1509 dbSNP
rs999138731 1511 dbSNP
rs575955380 1517 dbSNP
rs1394392726 1521 dbSNP
rs1391059151 1522 dbSNP
rs1046383854 1526 dbSNP
rs1053883161 1527 dbSNP
rs1281137010 1536 dbSNP
rs936900039 1544 dbSNP
rs142940929 1545 dbSNP
rs1479350337 1546 dbSNP
rs1406978538 1550 dbSNP
rs978341688 1551 dbSNP
rs1269086306 1553 dbSNP
rs967052099 1562 dbSNP
rs1455899521 1563 dbSNP
rs916941704 1569 dbSNP
rs894430669 1570 dbSNP
rs1183734584 1583 dbSNP
rs1038455758 1584 dbSNP
rs1173101625 1593 dbSNP
rs941445176 1601 dbSNP
rs538730749 1602 dbSNP
rs1367762305 1603 dbSNP
rs1403302938 1607 dbSNP
rs1180083900 1609 dbSNP
rs1462590721 1616 dbSNP
rs1263281206 1621 dbSNP
rs994693296 1624 dbSNP
rs1305275996 1626 dbSNP
rs186778173 1630 dbSNP
rs1047540233 1631 dbSNP
rs1014828906 1639 dbSNP
rs758393712 1655 dbSNP
rs753801566 1659 dbSNP
rs1268649976 1662 dbSNP
rs929249103 1668 dbSNP
rs12105737 1684 dbSNP
rs1188803155 1686 dbSNP
rs1260184530 1687 dbSNP
rs976371659 1689 dbSNP
rs148557151 1696 dbSNP
rs1387142466 1706 dbSNP
rs910208934 1720 dbSNP
rs989934456 1721 dbSNP
rs1398376900 1730 dbSNP
rs12105323 1740 dbSNP
rs1431125828 1742 dbSNP
rs1290402694 1754 dbSNP
rs568717125 1755 dbSNP
rs1381542710 1758 dbSNP
rs1275171052 1760 dbSNP
rs1319986891 1761 dbSNP
rs548915707 1765 dbSNP
rs900611998 1775 dbSNP
rs977607056 1776 dbSNP
rs1218452599 1778 dbSNP
rs181948693 1792 dbSNP
rs749000097 1796 dbSNP
rs1184701527 1798 dbSNP
rs144735324 1800 dbSNP
rs1159318457 1802 dbSNP
rs1457577101 1809 dbSNP
rs76100632 1813 dbSNP
rs34020562 1815 dbSNP
rs1446381194 1817 dbSNP
rs189430957 1818 dbSNP
rs949703106 1819 dbSNP
rs540705427 1821 dbSNP
rs1384368738 1823 dbSNP
rs916889301 1826 dbSNP
rs1313717316 1836 dbSNP
rs546543317 1838 dbSNP
rs74372767 1839 dbSNP
rs561263131 1842 dbSNP
rs1305339424 1844 dbSNP
rs745579805 1846 dbSNP
rs755872582 1851 dbSNP
rs1204871956 1857 dbSNP
rs78796362 1859 dbSNP
rs575962823 1869 dbSNP
rs901635098 1870 dbSNP
rs1355205588 1871 dbSNP
rs778796727 1888 dbSNP
rs1040331392 1889 dbSNP
rs1472102697 1895 dbSNP
rs943273588 1900 dbSNP
rs910249186 1901 dbSNP
rs1030307461 1902 dbSNP
rs140032700 1905 dbSNP
rs1443965408 1910 dbSNP
rs1277342908 1911 dbSNP
rs1350267815 1914 dbSNP
rs1297466767 1915 dbSNP
rs76014609 1925 dbSNP
rs924372594 1926 dbSNP
rs1223414788 1929 dbSNP
rs578113215 1937 dbSNP
rs1273834820 1949 dbSNP
rs113979210 1953 dbSNP
rs1202703510 1957 dbSNP
rs531274278 1958 dbSNP
rs114313427 1959 dbSNP
rs949624314 1962 dbSNP
rs1134281 1963 dbSNP
rs1171887205 1969 dbSNP
rs1134282 1974 dbSNP
rs1411096078 1980 dbSNP
rs959199002 1984 dbSNP
rs1167935840 1994 dbSNP
rs185496445 1995 dbSNP
rs111409314 1996 dbSNP
rs1436436668 1998 dbSNP
rs180788506 2007 dbSNP
rs1025686919 2009 dbSNP
rs1341582305 2017 dbSNP
rs10191309 2023 dbSNP
rs1212944012 2026 dbSNP
rs941765278 2026 dbSNP
rs1360489549 2027 dbSNP
rs886055753 2033 dbSNP
rs1193260033 2042 dbSNP
rs1270817868 2044 dbSNP
rs1489762656 2049 dbSNP
rs112640330 2050 dbSNP
rs901711587 2055 dbSNP
rs1476347666 2059 dbSNP
rs983707854 2060 dbSNP
rs1040599322 2065 dbSNP
rs1225231320 2067 dbSNP
rs533012333 2078 dbSNP
rs1274342336 2084 dbSNP
rs1030650439 2091 dbSNP
rs565843761 2093 dbSNP
rs1386510504 2097 dbSNP
rs1055957 2104 dbSNP
rs866602889 2106 dbSNP
rs7593437 2109 dbSNP
rs561270970 2129 dbSNP
rs114055204 2130 dbSNP
rs115320284 2132 dbSNP
rs386655913 2133 dbSNP
rs146051563 2134 dbSNP
rs376304622 2138 dbSNP
rs554398899 2139 dbSNP
rs896683367 2148 dbSNP
rs1427807830 2154 dbSNP
rs1055769273 2157 dbSNP
rs537737062 2159 dbSNP
rs910147437 2170 dbSNP
rs905491508 2171 dbSNP
rs1167998988 2181 dbSNP
rs1383063795 2185 dbSNP
rs868812922 2187 dbSNP
rs984303182 2188 dbSNP
rs1159549813 2192 dbSNP
rs1490182603 2193 dbSNP
rs1477385785 2198 dbSNP
rs941736254 2200 dbSNP
rs1399498191 2205 dbSNP
rs1320390462 2212 dbSNP
rs142744393 2214 dbSNP
rs951422852 2217 dbSNP
rs1454700541 2222 dbSNP
rs1201199516 2227 dbSNP
rs1340135593 2234 dbSNP
rs1025592210 2244 dbSNP
rs112366807 2249 dbSNP
rs1352529948 2256 dbSNP
rs933130345 2260 dbSNP
rs372826467 2264 dbSNP
rs74714426 2265 dbSNP
rs11895663 2271 dbSNP
rs1240693575 2272 dbSNP
rs563225873 2293 dbSNP
rs964607329 2294 dbSNP
rs1365918516 2303 dbSNP
rs1007820624 2305 dbSNP
rs111236896 2310 dbSNP
rs554962698 2329 dbSNP
rs760087328 2330 dbSNP
rs1000108682 2333 dbSNP
rs1471223698 2336 dbSNP
rs902882836 2341 dbSNP
rs1285236412 2342 dbSNP
rs1401520756 2346 dbSNP
rs536613273 2347 dbSNP
rs1392211150 2353 dbSNP
rs1224422341 2357 dbSNP
rs1041390393 2361 dbSNP
rs1337329393 2365 dbSNP
rs1226413497 2367 dbSNP
rs78632389 2369 dbSNP
rs1287506723 2370 dbSNP
rs1439668378 2373 dbSNP
rs369132848 2376 dbSNP
rs1253763442 2377 dbSNP
rs1482606068 2380 dbSNP
rs1329404893 2381 dbSNP
rs374647775 2382 dbSNP
rs1481865588 2383 dbSNP
rs371656534 2385 dbSNP
rs1181956510 2386 dbSNP
rs367939304 2388 dbSNP
rs376697878 2391 dbSNP
rs1174848359 2392 dbSNP
rs1481716014 2392 dbSNP
rs72239408 2394 dbSNP
rs917003468 2394 dbSNP
rs1410679543 2399 dbSNP
rs1180506703 2403 dbSNP
rs1406731154 2403 dbSNP
rs1471331596 2409 dbSNP
rs1233791349 2410 dbSNP
rs1227601131 2411 dbSNP
rs1252522963 2412 dbSNP
rs1187510128 2413 dbSNP
rs1441188126 2414 dbSNP
rs1164407716 2417 dbSNP
rs1189999623 2417 dbSNP
rs1203934227 2417 dbSNP
rs1223375041 2417 dbSNP
rs1267341965 2417 dbSNP
rs1270084482 2417 dbSNP
rs1291565057 2417 dbSNP
rs1339691556 2417 dbSNP
rs1365975865 2417 dbSNP
rs1388378324 2417 dbSNP
rs1426378920 2417 dbSNP
rs1429375024 2417 dbSNP
rs1429627838 2417 dbSNP
rs1490922772 2417 dbSNP
rs557793458 2417 dbSNP
rs60946199 2417 dbSNP
rs750456527 2417 dbSNP
rs1486508585 2418 dbSNP
rs539716492 2418 dbSNP
rs1204323176 2430 dbSNP
rs1055519954 2437 dbSNP
rs1184271130 2438 dbSNP
rs1266429128 2438 dbSNP
rs1221882338 2439 dbSNP
rs1387387554 2441 dbSNP
rs937513289 2450 dbSNP
rs910051878 2451 dbSNP
rs1162488736 2453 dbSNP
rs984371932 2457 dbSNP
rs951619248 2458 dbSNP
rs1447292437 2463 dbSNP
rs189985829 2468 dbSNP
rs977177909 2482 dbSNP
rs1338134103 2483 dbSNP
rs1384598337 2485 dbSNP
rs1452673163 2489 dbSNP
rs1387476920 2490 dbSNP
rs1317857374 2495 dbSNP
rs965380012 2496 dbSNP
rs184846680 2498 dbSNP
rs1266719604 2499 dbSNP
rs1464837246 2504 dbSNP
rs1006938955 2506 dbSNP
rs55672227 2507 dbSNP
rs1245020918 2511 dbSNP
rs1471944345 2512 dbSNP
rs1181454607 2513 dbSNP
rs953229799 2514 dbSNP
rs1419388127 2515 dbSNP
rs1161091619 2519 dbSNP
rs112697749 2521 dbSNP
rs771860664 2522 dbSNP
rs903082641 2532 dbSNP
rs567728333 2540 dbSNP
rs1041611605 2541 dbSNP
rs35555555 2542 dbSNP
rs113499955 2546 dbSNP
rs1224608009 2550 dbSNP
rs1265109700 2553 dbSNP
rs1440702371 2556 dbSNP
rs1055954302 2557 dbSNP
rs567261627 2558 dbSNP
rs1481740762 2562 dbSNP
rs886129847 2564 dbSNP
rs910083008 2579 dbSNP
rs1472238715 2585 dbSNP
rs1047932574 2586 dbSNP
rs933119182 2589 dbSNP
rs1048527114 2595 dbSNP
rs930122952 2597 dbSNP
rs1411252770 2599 dbSNP
rs1306586951 2600 dbSNP
rs923063638 2602 dbSNP
rs1317741785 2608 dbSNP
rs1038846555 2609 dbSNP
rs192860944 2625 dbSNP
rs375316628 2638 dbSNP
rs1273769821 2639 dbSNP
rs112334929 2640 dbSNP
rs1317010074 2641 dbSNP
rs1482567749 2641 dbSNP
rs747942930 2643 dbSNP
rs190011414 2644 dbSNP
rs376041742 2648 dbSNP
rs201549891 2649 dbSNP
rs958093742 2650 dbSNP
rs541195552 2653 dbSNP
rs1166251267 2654 dbSNP
rs560721519 2655 dbSNP
rs1425748724 2657 dbSNP
rs1323318794 2658 dbSNP
rs967173532 2665 dbSNP
rs1325934007 2666 dbSNP
rs561478241 2672 dbSNP
rs1387656728 2678 dbSNP
rs1002384714 2681 dbSNP
rs1164829846 2686 dbSNP
rs1449364925 2689 dbSNP
rs1020627753 2696 dbSNP
rs113452011 2706 dbSNP
rs1274119562 2712 dbSNP
rs756416052 2715 dbSNP
rs1188348062 2726 dbSNP
rs1017179295 2730 dbSNP
rs575999376 2733 dbSNP
rs1001263596 2734 dbSNP
rs1449813593 2735 dbSNP
rs1489811652 2739 dbSNP
rs888215981 2748 dbSNP
rs1293633185 2753 dbSNP
rs1223220487 2756 dbSNP
rs78803281 2757 dbSNP
rs997637222 2761 dbSNP
rs143083178 2774 dbSNP
rs897284405 2777 dbSNP
rs781356665 2781 dbSNP
rs572277348 2787 dbSNP
rs1444836784 2797 dbSNP
rs1215748054 2800 dbSNP
rs1362265555 2801 dbSNP
rs1390942764 2802 dbSNP
rs1038815832 2805 dbSNP
rs1041735666 2805 dbSNP
rs944292682 2810 dbSNP
rs1247198394 2823 dbSNP
rs554026019 2843 dbSNP
rs985457797 2844 dbSNP
rs936631302 2856 dbSNP
rs903722294 2860 dbSNP
rs1043624077 2863 dbSNP
rs535682330 2868 dbSNP
rs1246860195 2879 dbSNP
rs1304130601 2896 dbSNP
rs1461509981 2898 dbSNP
rs1429737238 2900 dbSNP
rs925370437 2901 dbSNP
rs978136600 2904 dbSNP
rs1189149428 2905 dbSNP
rs1367094760 2911 dbSNP
rs967206153 2916 dbSNP
rs1472641442 2918 dbSNP
rs777886729 2920 dbSNP
rs1353211893 2925 dbSNP
rs1456084148 2928 dbSNP
rs1020114194 2929 dbSNP
rs755062756 2932 dbSNP
rs959966437 2944 dbSNP
rs752079204 2947 dbSNP
rs1398010491 2952 dbSNP
rs115337911 2957 dbSNP
rs1243874844 2962 dbSNP
rs528700525 2963 dbSNP
rs1331205367 2967 dbSNP
rs888081304 2975 dbSNP
rs926680267 2977 dbSNP
rs13035924 2995 dbSNP
rs1201837437 2998 dbSNP
rs1197580702 3013 dbSNP
rs549547738 3021 dbSNP
rs1441483998 3027 dbSNP
rs549391328 3030 dbSNP
rs1222875502 3033 dbSNP
rs993872952 3043 dbSNP
rs897351786 3044 dbSNP
rs962868526 3047 dbSNP
rs60188280 3048 dbSNP
rs944314729 3052 dbSNP
rs1170886374 3054 dbSNP
rs951665583 3057 dbSNP
rs890064189 3058 dbSNP
rs184208281 3060 dbSNP
rs551709580 3061 dbSNP
rs533475445 3062 dbSNP
rs901528725 3066 dbSNP
rs1017293811 3071 dbSNP
rs1331598330 3073 dbSNP
rs1007296517 3079 dbSNP
rs1221383137 3079 dbSNP
rs78448004 3081 dbSNP
rs903691214 3091 dbSNP
rs1343919011 3097 dbSNP
rs142025701 3098 dbSNP
rs1042535409 3101 dbSNP
rs945468122 3104 dbSNP
rs369809202 3108 dbSNP
rs540639528 3109 dbSNP
rs867125872 3117 dbSNP
rs137927700 3121 dbSNP
rs79459734 3139 dbSNP
rs1371835414 3145 dbSNP
rs543152200 3148 dbSNP
rs1196908733 3155 dbSNP
rs1462913505 3173 dbSNP
rs760403027 3174 dbSNP
rs960113927 3181 dbSNP
rs1170649936 3183 dbSNP
rs1174349819 3185 dbSNP
rs554090196 3191 dbSNP
rs926644544 3204 dbSNP
rs1199923958 3206 dbSNP
rs1307175098 3209 dbSNP
rs979947808 3209 dbSNP
rs1368268702 3210 dbSNP
rs563929661 3213 dbSNP
rs941429234 3214 dbSNP
rs12105620 3216 dbSNP
rs571932067 3217 dbSNP
rs554137984 3224 dbSNP
rs1339624826 3226 dbSNP
rs1204938844 3229 dbSNP
rs1266377369 3231 dbSNP
rs951691705 3235 dbSNP
rs767027446 3238 dbSNP
rs993909026 3239 dbSNP
rs1266771278 3240 dbSNP
rs578045082 3240 dbSNP
rs146938239 3243 dbSNP
rs977434967 3245 dbSNP
rs1388623504 3247 dbSNP
rs1449057834 3248 dbSNP
rs965673338 3250 dbSNP
rs1017261274 3256 dbSNP
rs1201172470 3271 dbSNP
rs28395237 3272 dbSNP
rs889919327 3282 dbSNP
rs1321929430 3290 dbSNP
rs1050008142 3296 dbSNP
rs1001115453 3300 dbSNP
rs1227146056 3302 dbSNP
rs903889686 3307 dbSNP
rs1237849327 3308 dbSNP
rs556931722 3309 dbSNP
rs543448326 3318 dbSNP
rs564625765 3325 dbSNP
rs1465741322 3335 dbSNP
rs1210715519 3341 dbSNP
rs1246243213 3349 dbSNP
rs1056377792 3350 dbSNP
rs113664962 3351 dbSNP
rs551496841 3362 dbSNP
rs1334790576 3367 dbSNP
rs145428429 3372 dbSNP
rs1162427474 3378 dbSNP
rs1417124125 3380 dbSNP
rs1457679110 3389 dbSNP
rs938529886 3391 dbSNP
rs1407142424 3394 dbSNP
rs192677933 3395 dbSNP
rs1433914475 3396 dbSNP
rs980019405 3401 dbSNP
rs1047612724 3412 dbSNP
rs1394727588 3424 dbSNP
rs187651830 3424 dbSNP
rs376400858 3424 dbSNP
rs374884797 3425 dbSNP
rs113896991 3426 dbSNP
rs919620034 3428 dbSNP
rs1328499619 3432 dbSNP
rs1210891459 3435 dbSNP
rs977027690 3442 dbSNP
rs529532932 3448 dbSNP
rs972446543 3452 dbSNP
rs964263453 3457 dbSNP
rs1242386217 3461 dbSNP
rs770093557 3463 dbSNP
rs1161202088 3470 dbSNP
rs1462303127 3482 dbSNP
rs561953841 3484 dbSNP
rs1399676324 3488 dbSNP
rs781309030 3495 dbSNP
rs1008354997 3496 dbSNP
rs1464211632 3502 dbSNP
rs1262877797 3503 dbSNP
rs1312679100 3506 dbSNP
rs549915131 3510 dbSNP
rs1351445284 3515 dbSNP
rs1240122263 3528 dbSNP
rs1022033387 3533 dbSNP
rs1359392787 3535 dbSNP
rs1313496676 3536 dbSNP
rs956564417 3545 dbSNP
rs954277504 3546 dbSNP
rs1219928509 3547 dbSNP
rs1280793193 3549 dbSNP
rs1310685671 3552 dbSNP
rs1028488207 3554 dbSNP
rs112322717 3558 dbSNP
rs1483228779 3566 dbSNP
rs904123163 3570 dbSNP
rs1319970288 3572 dbSNP
rs62191371 3580 dbSNP
rs1003427089 3589 dbSNP
rs1191318223 3591 dbSNP
rs62191370 3599 dbSNP
rs538781613 3616 dbSNP
rs1431129684 3618 dbSNP
rs1387343547 3619 dbSNP
rs1370770316 3629 dbSNP
rs1290421067 3632 dbSNP
rs1306523234 3633 dbSNP
rs1045064036 3634 dbSNP
rs1437747627 3635 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gcggcagggcccucGGGGUGAGu 5'
                        |||||||| 
Target 5' ---------caccuCCCCACUCu 3'
 		1 - 14
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000258403.3 | 3UTR | CACCUCCCCACUCUCUCUUUCUCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
85 hsa-miR-4745-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100716 TJAP1 tight junction associated protein 1 2 2
MIRT183592 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT338035 DAZAP2 DAZ associated protein 2 2 4
MIRT395801 SPCS3 signal peptidase complex subunit 3 2 2
MIRT443946 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 2 2
MIRT450579 HIST1H2BG histone cluster 1 H2B family member g 2 6
MIRT451616 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT452330 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453278 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT455213 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT455469 LYPLA2 lysophospholipase II 2 2
MIRT456502 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT456686 LDB1 LIM domain binding 1 2 2
MIRT456914 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457602 IDS iduronate 2-sulfatase 2 2
MIRT457849 RNASEH2B ribonuclease H2 subunit B 2 4
MIRT458454 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT460178 UNK unkempt family zinc finger 2 6
MIRT461464 SLC19A3 solute carrier family 19 member 3 2 2
MIRT464738 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465278 TRIM28 tripartite motif containing 28 2 2
MIRT468449 SETD1B SET domain containing 1B 2 2
MIRT468619 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT469151 RNF121 ring finger protein 121 2 2
MIRT470072 PTGES2 prostaglandin E synthase 2 2 2
MIRT470171 PSMD11 proteasome 26S subunit, non-ATPase 11 2 4
MIRT473155 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT474307 LAMC1 laminin subunit gamma 1 2 2
MIRT474781 KIAA0895L KIAA0895 like 2 2
MIRT476482 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477612 EFNA3 ephrin A3 2 2
MIRT479523 CDCA4 cell division cycle associated 4 2 2
MIRT479972 CARD10 caspase recruitment domain family member 10 2 2
MIRT480409 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480425 C17orf85 nuclear cap binding subunit 3 2 2
MIRT483571 SYT2 synaptotagmin 2 2 2
MIRT483663 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT484531 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484614 SIX3 SIX homeobox 3 2 6
MIRT485896 ZFP36 ZFP36 ring finger protein 2 2
MIRT486504 MYH11 myosin heavy chain 11 2 2
MIRT487506 GRK5 G protein-coupled receptor kinase 5 2 2
MIRT488851 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489463 MSC musculin 2 2
MIRT491168 LRP3 LDL receptor related protein 3 2 2
MIRT496626 TMEM67 transmembrane protein 67 2 2
MIRT497615 ANG angiogenin 2 2
MIRT497765 KIAA0895 KIAA0895 2 2
MIRT499679 MRE11A MRE11 homolog, double strand break repair nuclease 2 6
MIRT499772 SLC29A2 solute carrier family 29 member 2 2 2
MIRT501744 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT504993 ZNF652 zinc finger protein 652 2 2
MIRT511663 HIST1H3C histone cluster 1 H3 family member c 2 2
MIRT511689 HIST1H2BO histone cluster 1 H2B family member o 2 4
MIRT511702 HIST1H2BL histone cluster 1 H2B family member l 2 4
MIRT511733 HIST1H2BE histone cluster 1 H2B family member e 2 8
MIRT512857 TBC1D13 TBC1 domain family member 13 2 2
MIRT513443 EMP1 epithelial membrane protein 1 2 6
MIRT515680 TFPI tissue factor pathway inhibitor 2 2
MIRT523528 GLUL glutamate-ammonia ligase 2 2
MIRT525545 PHB2 prohibitin 2 2 4
MIRT526208 SNX24 sorting nexin 24 2 2
MIRT531555 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT533763 TMEM135 transmembrane protein 135 2 2
MIRT545581 SNRPA1 small nuclear ribonucleoprotein polypeptide A' 2 2
MIRT552433 ZNF460 zinc finger protein 460 2 2
MIRT561158 BCL2L12 BCL2 like 12 2 2
MIRT562344 EXOSC2 exosome component 2 2 2
MIRT570658 KDM6B lysine demethylase 6B 2 2
MIRT571075 TCHHL1 trichohyalin like 1 2 2
MIRT571331 TPCN2 two pore segment channel 2 2 2
MIRT571601 TOB2 transducer of ERBB2, 2 2 2
MIRT573012 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT609042 EP300 E1A binding protein p300 2 2
MIRT613397 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT635588 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT644753 TXNRD3NB thioredoxin reductase 3 neighbor 2 2
MIRT661117 FPR1 formyl peptide receptor 1 2 2
MIRT690102 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT694971 PLAC8 placenta specific 8 2 2
MIRT695514 ALPI alkaline phosphatase, intestinal 2 2
MIRT695576 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT699569 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT701990 MIER3 MIER family member 3 2 2
MIRT725462 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4745-5p Cisplatin approved 84093 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4745 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4745 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4745 Plx-4720 24180719 NSC757438 sensitive High Thyroid Cancer cell line (8505c, BCPAP)
hsa-mir-4745 Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-4745 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4745 Androstenedione+Anastrozole sensitive cell line (MCF-7)
hsa-mir-4745 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-4745-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4745-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4745-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4745-5p Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4745-5p Curcumin 969516 NSC32982 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4745-5p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4745-5p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-4745-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (H460)
hsa-miR-4745-5p Docetaxel 148124 NSC628503 approved sensitive High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-4745-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-4745-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4745-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-4745-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4745-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (total RNA)
hsa-miR-4745-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4745-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4745-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4745-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4745-5p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4745-5p Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-4745-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4745-5p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-4745-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4745-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4745-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)

Error report submission