miRTarBase - #MIRT463104


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pre-miRNA Information
pre-miRNA hsa-mir-378c   
Genomic Coordinates chr10: 130962588 - 130962668
Description Homo sapiens miR-378c stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-378c
Sequence 11| ACUGGACUUGGAGUCAGAAGAGUGG |35
Evidence Experimental
Experiments SOLiD
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 12 10 - 130962647 29233923 MiREDiBase
A-to-I 21 10 - 130962638 22327324, 27229138, 29165639 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1255712575 1 dbSNP
rs954998865 5 dbSNP
rs1476405711 7 dbSNP
rs1187159745 11 dbSNP
rs936928990 13 dbSNP
rs924224817 14 dbSNP
rs1031754294 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF609   
Synonyms -
Description zinc finger protein 609
Transcript NM_015042   
Expression
Putative miRNA Targets on ZNF609
3'UTR of ZNF609
(miRNA target sites are highlighted)		 
>ZNF609|NM_015042|3'UTR
   1 GAATGACACCAAGTGCCCGGATAAAGTCAGCTTCACGGGCCCGGACTGGCTTACCCAAGGAGGTGCTGAAGGTGCCGTTT
  81 AGACATCAGTTAAATGGTGTTGATCATCCTGTTTGCCGTTTCCACCATGACTGAAGGCAGACCCTTGGCTATCTCACCTC
 161 CACCAGACCTCCGGACTACCTGACCCTACCTCTTCCTCAGGAGCTGGAGAGCTGGTACTTAGCAAAAATATTTATTCTCT
 241 CAGCCACAGTTATGACTATTGTGGCCTCTGTGGAGATGAAGGCACGGGAAGCAACCAGGGGAACATGGCCTCAGCCCAGA
 321 GAAGCCACTGCTCTGTTCCCCAAGCCCTTGGTCTGCTGCTGGAGCAGTACCAGCCCCCCCGCCCACCAGGGAGGGACCCC
 401 CACCCCCAAGCACTGGGTAAGGTCTGAAGACAGCACAGCAGCCATACCCCTCACCATCATTACCACCATCACCAGATTCT
 481 GCATCTCCCTAGTGCTTTGCACCCTGGGAATTGGCAGCATGTGGAGGAACTAGAATCTCAGGAAAGAAATTGGGGGTTGT
 561 TTTCTACATAATTGTGAAAACAAGGTCTTCAAATGTGGAGACTTCTCCCCATTTACATGAGCACATATAAACGCTCACAA
 641 CCTAGCCTGGAAAGGAAGACCAAGGCATCTGCCCCAACATGGCCTTGAGCTGCCTGTGAGGCAGGGGGCAGGGGTTCCAA
 721 CACCAGCACAGGGCTCCCCAGGGACACTGGGAGCAAGCTGGTGCTGGAGCATGAATGACGTCTGTGAAGTAGAACCTGCG
 801 TCCCCACTAAGTCCTGCTGCTTCTTATTCCCCAACTCCTTGCCCTTTTCCCTTCCCTCCTAACCCCTTGGTGCCTTTCCC
 881 AGGGGGATCCCCACACTGGTCTTGCCTCTTCTTTTCCACTGCTTGGCTCTTAAGCCTCAGGCAGATAAACTAGTATTCCC
 961 CCCAGCTTGGGGAACCTTGGAGTCTGCCAGGTCACCTTAGGGCAAGGCCCAGAAGGCAGCCCCTGGGAGCACCCAGCAGT
1041 TCTTGGAGATGTCCTGTCATCTAGCCATCTGATATCTTCCTCATTTGAGGCCACAGATATATACAGCCCAATTCCTCTGT
1121 CTACAAGTACATGATTTTATATAGCTCAGTCTATAACCTCCATGTGGGCCAATATAAGCTGTGTTTCTTGGTAACACATA
1201 TTTTGTTTGAGGGGCCACTGGCCATGGGAGGTTATTTGTTCCTTAGACCCTGGAATAACACATCCAAGCCATTACTTATT
1281 AGAGTCTCAGAATGTACTCAGTGGAGCTGTGCTTTGAGGCAGCCAACATTTCTCTGCTCTCCTTAGAAATGCAGTCTCCC
1361 AATGGAAGCTTTATACTCTTTGTACTGGGAAAGTGAGGATGATTTGGTAGCTTTATTGGGGTCATGTCTTCCCCAAGGTG
1441 TGGGGAGCTTAGCTTACTTGGCTTTTGAGGTATCATCCCTCTGTTCTCCCCTCCTATCTTTCCATGACCCTCTGGATTGA
1521 GAGAGAGAGATAAAGACTGACAGACACCAGTGTAGGCTGGAAAAGGGAGTGTGTGACCAGAGTGCCAAAAGTGACTAGGA
1601 GCAGGAACTTGGCTCCGACTCAGTTTGGAAAATGGGAAATAGGGGACAGTAAGCACAATGCCCAGTAGTAGTTGATTTCC
1681 AAGGACCCTGGAACCCTACACTTGAGAGGCTTAGGGTCACCATCTGCTCAAGAGGATCCCCTCTGATCTACAGGCCTTTT
1761 CCCTAGGTTTCTGCCTCCTCGTTTTTGTTCAAGTTGGGTTCTGAGTCCTCCCCAAAAACCATTGTTTTAGACCTCTTGGC
1841 AGGGCCCCAAAACAGCCTCCCTCATACCCATCATTCCCTCTGCCTTCTGCTGCCCTCATGGGCAGTGCTCTGAGCAGTGA
1921 CCTCCCTTTCCTCCGTGGAAGTAGCTAGTGCAGACACCGTCATCCCACCCCACCTGAGTCACCCCAACCAAGAGGGTGAC
2001 TGAATTTCAGCCTGATTATGCCCTCCTGGGGCTCCTGTGAGGTGGAGCCAAGGTTCCCTCTCTGTTCCTGTTTGTTTTTA
2081 AATATTGTTGTGTGTTTTGTATCTGTGGCACTGGCCTGCAGCATACTCTGTATATATTGTAAAGAAACCGTTAGGAGTAA
2161 TTTTCTTTTGCATTGGGCAGGCATGGCCCTGCATTCCTGCCCTTTCCACTCATTCTGTAACACAGAGGACGAACTTCTGT
2241 ATTAGCTGGGCAGCCTTGGGTTCTCCAGAAGAGAACAGGTTTTTCTTTTCCTTTTTAATTTTTCTTCTTAAACATTTGGC
2321 TCTTTGATCCTCATATCCAAGTCTCCCCTGAAGAGTAGGAGCTGCTCAGAAGAGCAGGTGAAAGCCACCATGGCAGATCC
2401 TGATGCCTGCCGGGCCTAGTCTTCCCTCTGAAATAACATGAAGCAGCAGCTGTGGAGATTCTTGACAAGTGCTGAGTGAA
2481 AGATTTGCTGCCCACCTCTACATGGGGAGGAGAAACACAGGTGGGAGCTACCTGTGGCATCCATGACCTAGTCAGAGGGA
2561 TGAGATGCTCAGCAGGGGTCCCCATCCTATCCCACCCCACAAACAAAGGCTGGAAAAATTTGCTACCAAGGGCCAAGACC
2641 ACCAGACCAAGCCTGTTTATGAGCCACCCCTGCCCAGGCCCTCACAGACATTGCTCACGGGGCTTCCCATAGAGGAGAAG
2721 CTAAAGAGGGAGGGGGCCTCATCCCCAGATAGATCAGGCAAGGCTTGGAGAGCTGCTCTTTAGGATCCACATCAACTACT
2801 TCCTCATTTTAAGGTATGGCAGTTCCCTTCATCCCCTTTTCCTGCCTTGTACATGTACATGTATGAAATTTCCTTCTCTT
2881 ACCGAACTCTCTCCACACATCACAAGGTCAAAGAACCACACGCTTAGAAGGGTAAGAGGGCACCCTATGAAATGAAATGG
2961 TGATTTCTTGAGTCTCTTTTTTCCACGTTTAAGGGGCCATGGCAGGACTTAGAGTTGCGAGTTAAGACTGCAGAGGGCTA
3041 GAGAATTATTTCATACAGGCTTTGAGGCCACCCATGTCACTTATCCCGTATACCCTCTCACCATCCCCTTGTCTACTCTG
3121 ATGCCCCCAAGATGCAACTGGGCAGCTAGTTGGCCCCATAATTCTGGGCCTTTGTTGTTTGTTTTAATTACTTGGGCATC
3201 CCAGGAAGCTTTCCAGTGATCTCCTACCATGGGCCCCCCTCCTGGGATCAAGCCCCTCCCAGGCCCTGTCCCCAGCCCCT
3281 CCTGCCCCAGCCCACCCGCTTGCCTTGGTGCTCAGCCCTCCCATTGGGAGCAGGTTGGGGCGAGCTGGAGGCCCGGGCTG
3361 GAGGGGCAGTGTTGCTGTTCATAGATTTTGTTCCATTGGCGTTGCTCTGTTGAATTTAATTTCAGTCTTCCTGATTCTTC
3441 CCTTCTGTAAAGTGTACATTACCAAGTTCCTTGTTTTTTTATATATATATATAAATATATATATATACAAACTGTACTCT
3521 TTTTGCCTTTGTACATTCAGGCAAGAAGAGAAAATAAATCTTTTTAAGAGACAATCACAAATCTGTGAGGGCTGCTGGTT
3601 ATTTCTCCTGGAGTTTGCTGCTGAGCTGCCTCTTCCTTCCTCCCAATTTTCCTGTTCTCCCTCAGCTCTCCTGATCTTCC
3681 TGGCCCTGCTCCATATGCATCCTCAGCTTCACTTTCCCTGGCTGATGGCAAGCTGTTGAATCCAGTGTCCAGACTACCTG
3761 CCTTGTAACCCTTTTCTGCCCAGCATTGTTTTCTGGCTTGGCCACTGGCTTAGCCCAGGAGCTTTACTCTGTGCCCTGGC
3841 CTCCCCTCTCTTCACCTTTAGATTTCCATTCACCGAAGTGGCTTTGGACCCCTGGGTACTCTGGGACCTGTTTCCTGGAG
3921 GCCCTGGCTTGGGACACTCACCTGTGAAACTATGCAGCTGGGAGCTCTCTGCCTAAGAGTTTGCACTATTTAAACCTGCC
4001 TGGGAGTTAGGACGGATGGTTTTAGGAATGACCGGAAAACTACCCCTAAAACTCCCCCGACATTCCAGCCTCTAGAATGC
4081 TCTGATCCAGAGCTCAGTGGATGATTCCCAGCTGGTGGACTCCTGTGGCTACCCCATCAGAACAAGGGCTAAGGGTTTAT
4161 GGGTCAAGAGTATTTGATCAGAATTTTAAAGGGTGGTATACTCTGAAACACAGCCCAACCAAACCATTGTTTGGCCGCTT
4241 TCTCTTTTCCTCTACCTTCCTCATCCCCACTTTTTTCCCTTTCTCTCTACTTCCTCTTCTTAATTGGCTTTGGAATTGAA
4321 ATATATTTTTAAATTATTTGTTGTATTTATTGAATAAAGTTTTTAATGTCCCTGTTCTTAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggugaGAAGACUGAGGU-UCAGGUCa 5'
               || :||| ||||  |||||| 
Target 5' gcaagCTGTTGAATCCAGTGTCCAGa 3'
 3728 - 3753 140.00 -22.30
2 
miRNA  3' ggUGAGAAGACUGAGGUUCAGGUca 5'
            |:|| |||| || ||||| ||  
Target 5' caATTCCTCTGTCTACAAGTACAtg 3'
 1109 - 1133 135.00 -14.50
3 
miRNA  3' ggUGAGAAGACUGAGGUUCAGGUCa 5'
            :|||| :||| |::|| |:||| 
Target 5' ttGCTCTGTTGAATTTAATTTCAGt 3'
 3402 - 3426 135.00 -16.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30050136 172 COSMIC
COSN6544746 206 COSMIC
COSN26595893 324 COSMIC
COSN31563465 349 COSMIC
COSN31563134 423 COSMIC
COSN23822071 593 COSMIC
COSN31578803 604 COSMIC
COSN31542854 634 COSMIC
COSN30174306 667 COSMIC
COSN31524218 685 COSMIC
COSN29775506 686 COSMIC
COSN31555837 693 COSMIC
COSN31588461 980 COSMIC
COSN21230052 1046 COSMIC
COSN22299331 1086 COSMIC
COSN15668684 1192 COSMIC
COSN23306446 1213 COSMIC
COSN1178949 1446 COSMIC
COSN31521619 1647 COSMIC
COSN29523538 1822 COSMIC
COSN22823797 1824 COSMIC
COSN30544466 2034 COSMIC
COSN17556946 2293 COSMIC
COSN26696384 2533 COSMIC
COSN32055660 2759 COSMIC
COSN8749358 2972 COSMIC
COSN1178951 3014 COSMIC
COSN29982416 3110 COSMIC
COSN1682267 3146 COSMIC
COSN31572637 3228 COSMIC
COSN22500326 3251 COSMIC
COSN31521919 3336 COSMIC
COSN26259072 3456 COSMIC
COSN28673126 3475 COSMIC
COSN30286156 3540 COSMIC
COSN30175550 3685 COSMIC
COSN9627757 3730 COSMIC
COSN26641104 3778 COSMIC
COSN20239997 3798 COSMIC
COSN30541850 3799 COSMIC
COSN31528071 3802 COSMIC
COSN19662538 3803 COSMIC
COSN30173133 3873 COSMIC
COSN29468766 3890 COSMIC
COSN30173172 3902 COSMIC
COSN31593025 4339 COSMIC
COSN31486097 4351 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1414271447 2 dbSNP
rs970276724 5 dbSNP
rs1373276966 6 dbSNP
rs753134385 13 dbSNP
rs775687999 14 dbSNP
rs1327987951 20 dbSNP
rs756230236 21 dbSNP
rs760849243 24 dbSNP
rs1002643362 26 dbSNP
rs777699529 29 dbSNP
rs11631564 31 dbSNP
rs539334650 34 dbSNP
rs771929155 35 dbSNP
rs1485039090 40 dbSNP
rs1217642739 43 dbSNP
rs376487587 45 dbSNP
rs768144370 46 dbSNP
rs775975321 48 dbSNP
rs1009260559 49 dbSNP
rs776516811 54 dbSNP
rs906170292 61 dbSNP
rs1341327620 62 dbSNP
rs1338666581 63 dbSNP
rs1002878506 79 dbSNP
rs908879544 83 dbSNP
rs373857394 87 dbSNP
rs1356174355 88 dbSNP
rs953033816 93 dbSNP
rs1408173111 97 dbSNP
rs1258776396 98 dbSNP
rs1005669340 102 dbSNP
rs1329902444 117 dbSNP
rs1411975787 118 dbSNP
rs1015661968 132 dbSNP
rs961425727 137 dbSNP
rs1417877938 143 dbSNP
rs191176762 144 dbSNP
rs921467488 146 dbSNP
rs932790327 155 dbSNP
rs1291966995 156 dbSNP
rs550223931 158 dbSNP
rs575731595 163 dbSNP
rs536779479 164 dbSNP
rs1200791803 167 dbSNP
rs1192166615 170 dbSNP
rs73454993 174 dbSNP
rs1478592710 186 dbSNP
rs1295137243 188 dbSNP
rs910460404 194 dbSNP
rs1053151751 198 dbSNP
rs893127435 200 dbSNP
rs1444716314 206 dbSNP
rs1329694572 213 dbSNP
rs1325664347 221 dbSNP
rs1011520624 229 dbSNP
rs1397360345 238 dbSNP
rs1166405788 239 dbSNP
rs1398431969 246 dbSNP
rs913713105 247 dbSNP
rs1177422878 254 dbSNP
rs1470992464 255 dbSNP
rs1044680428 256 dbSNP
rs1046114494 257 dbSNP
rs34414202 257 dbSNP
rs568046958 257 dbSNP
rs905708072 269 dbSNP
rs888693228 273 dbSNP
rs1455965266 278 dbSNP
rs1161921426 288 dbSNP
rs1005701824 292 dbSNP
rs1225622268 295 dbSNP
rs1343141398 296 dbSNP
rs1393481644 297 dbSNP
rs1303079595 312 dbSNP
rs1003084464 314 dbSNP
rs539141375 318 dbSNP
rs1035447348 322 dbSNP
rs886227387 323 dbSNP
rs769552726 324 dbSNP
rs1319094025 336 dbSNP
rs371834981 341 dbSNP
rs962998181 342 dbSNP
rs1344080742 344 dbSNP
rs974316098 347 dbSNP
rs773188577 348 dbSNP
rs1172735775 354 dbSNP
rs1454523077 361 dbSNP
rs1254728787 362 dbSNP
rs1184691686 365 dbSNP
rs1028965990 368 dbSNP
rs954246620 376 dbSNP
rs114094474 379 dbSNP
rs989367517 381 dbSNP
rs766825663 382 dbSNP
rs762877319 384 dbSNP
rs1215881283 388 dbSNP
rs752061745 399 dbSNP
rs1295940992 413 dbSNP
rs1283549705 417 dbSNP
rs1214437784 422 dbSNP
rs913745605 424 dbSNP
rs1489153302 426 dbSNP
rs934759231 427 dbSNP
rs988873862 432 dbSNP
rs945152595 433 dbSNP
rs1432318444 446 dbSNP
rs1373148955 468 dbSNP
rs1421734382 477 dbSNP
rs1311886956 478 dbSNP
rs137885321 490 dbSNP
rs1396597779 497 dbSNP
rs376536752 498 dbSNP
rs1473403820 520 dbSNP
rs1158588173 522 dbSNP
rs1378781755 535 dbSNP
rs576775782 544 dbSNP
rs766487692 551 dbSNP
rs1188251207 558 dbSNP
rs8034064 563 dbSNP
rs1299246074 566 dbSNP
rs769861178 582 dbSNP
rs1256972234 586 dbSNP
rs1211861488 587 dbSNP
rs562739308 590 dbSNP
rs1057390957 591 dbSNP
rs886260463 593 dbSNP
rs529830435 602 dbSNP
rs759829420 609 dbSNP
rs1015943831 610 dbSNP
rs1204291004 611 dbSNP
rs898850555 613 dbSNP
rs1308554970 624 dbSNP
rs1298328097 625 dbSNP
rs1227167527 626 dbSNP
rs1353021831 638 dbSNP
rs995766433 640 dbSNP
rs1028578904 647 dbSNP
rs773138187 659 dbSNP
rs1296199967 662 dbSNP
rs548290339 671 dbSNP
rs1355530240 675 dbSNP
rs1354944575 677 dbSNP
rs1030187767 678 dbSNP
rs998300208 678 dbSNP
rs559948317 680 dbSNP
rs1476280389 683 dbSNP
rs527283091 685 dbSNP
rs1482067058 686 dbSNP
rs552246560 690 dbSNP
rs1334784564 698 dbSNP
rs1271935234 707 dbSNP
rs1233402202 709 dbSNP
rs1356858800 710 dbSNP
rs1304385599 713 dbSNP
rs1033026927 722 dbSNP
rs1456932968 723 dbSNP
rs1373781327 726 dbSNP
rs988906324 731 dbSNP
rs989400059 736 dbSNP
rs183637600 745 dbSNP
rs1020880969 752 dbSNP
rs966570016 755 dbSNP
rs1463048533 756 dbSNP
rs1362182001 757 dbSNP
rs914624653 759 dbSNP
rs1419905195 762 dbSNP
rs767595978 763 dbSNP
rs1159627300 766 dbSNP
rs1377481468 767 dbSNP
rs1468399465 768 dbSNP
rs1254143975 771 dbSNP
rs1216152187 772 dbSNP
rs1357835638 781 dbSNP
rs539373427 783 dbSNP
rs947371342 784 dbSNP
rs1237797514 786 dbSNP
rs927728283 801 dbSNP
rs937795900 805 dbSNP
rs1233017568 807 dbSNP
rs1438477903 808 dbSNP
rs990939045 812 dbSNP
rs980548642 815 dbSNP
rs909552322 820 dbSNP
rs1443081669 821 dbSNP
rs1382801500 822 dbSNP
rs1158086505 851 dbSNP
rs781458647 855 dbSNP
rs1454460182 856 dbSNP
rs941026763 856 dbSNP
rs1037278050 857 dbSNP
rs1454090943 860 dbSNP
rs897397706 861 dbSNP
rs934175440 862 dbSNP
rs752936551 868 dbSNP
rs756597812 873 dbSNP
rs140864227 877 dbSNP
rs1485966466 879 dbSNP
rs938626845 880 dbSNP
rs370619429 887 dbSNP
rs1231681021 889 dbSNP
rs569455389 892 dbSNP
rs189172080 897 dbSNP
rs1235253439 906 dbSNP
rs1191326555 922 dbSNP
rs1324645228 923 dbSNP
rs1054505449 931 dbSNP
rs1310231246 937 dbSNP
rs1234878504 955 dbSNP
rs907733025 960 dbSNP
rs893181732 962 dbSNP
rs940500196 963 dbSNP
rs748232574 964 dbSNP
rs1316693364 970 dbSNP
rs1175931359 978 dbSNP
rs1020913667 983 dbSNP
rs1373039276 992 dbSNP
rs1194567044 995 dbSNP
rs1428569496 998 dbSNP
rs1264773422 999 dbSNP
rs552852289 1001 dbSNP
rs1208269196 1010 dbSNP
rs1280724388 1026 dbSNP
rs1037423060 1029 dbSNP
rs898881861 1032 dbSNP
rs1239535094 1035 dbSNP
rs1228138795 1041 dbSNP
rs1003849190 1046 dbSNP
rs1414336072 1063 dbSNP
rs1376314378 1064 dbSNP
rs1336512746 1066 dbSNP
rs1459473074 1073 dbSNP
rs555054479 1075 dbSNP
rs995938915 1084 dbSNP
rs868743379 1085 dbSNP
rs1267033376 1089 dbSNP
rs1476710197 1097 dbSNP
rs1431836424 1104 dbSNP
rs990622475 1105 dbSNP
rs573210910 1112 dbSNP
rs890106856 1118 dbSNP
rs1257746804 1120 dbSNP
rs1008911901 1127 dbSNP
rs1435855121 1131 dbSNP
rs962377981 1134 dbSNP
rs1196238278 1138 dbSNP
rs756345301 1140 dbSNP
rs1465333554 1147 dbSNP
rs375863286 1155 dbSNP
rs1319929500 1158 dbSNP
rs1168613198 1161 dbSNP
rs777989620 1164 dbSNP
rs1402617519 1165 dbSNP
rs534026949 1166 dbSNP
rs1271296896 1180 dbSNP
rs182308443 1190 dbSNP
rs1356218335 1192 dbSNP
rs1286150847 1193 dbSNP
rs778270072 1197 dbSNP
rs1335537470 1203 dbSNP
rs1329969357 1206 dbSNP
rs570629131 1211 dbSNP
rs1388321201 1212 dbSNP
rs956199741 1233 dbSNP
rs934279206 1236 dbSNP
rs1164884008 1245 dbSNP
rs1460448691 1250 dbSNP
rs1413965835 1260 dbSNP
rs1051745338 1264 dbSNP
rs186956641 1272 dbSNP
rs1232034292 1275 dbSNP
rs1182284514 1283 dbSNP
rs1318010900 1284 dbSNP
rs942853616 1286 dbSNP
rs368375839 1287 dbSNP
rs757778864 1289 dbSNP
rs893206167 1294 dbSNP
rs968824328 1294 dbSNP
rs1010269217 1298 dbSNP
rs980197356 1309 dbSNP
rs1222208775 1314 dbSNP
rs1350263307 1323 dbSNP
rs1487822317 1324 dbSNP
rs927309867 1330 dbSNP
rs544131414 1334 dbSNP
rs1369308688 1341 dbSNP
rs1193250225 1346 dbSNP
rs1442373387 1348 dbSNP
rs746461954 1363 dbSNP
rs907764237 1365 dbSNP
rs940532716 1378 dbSNP
rs562615474 1379 dbSNP
rs1406832018 1381 dbSNP
rs144690840 1383 dbSNP
rs768176877 1384 dbSNP
rs1441289864 1390 dbSNP
rs1393101170 1391 dbSNP
rs1192926397 1393 dbSNP
rs1468860011 1399 dbSNP
rs1477608825 1405 dbSNP
rs544345310 1412 dbSNP
rs907172299 1424 dbSNP
rs1242663668 1428 dbSNP
rs931755927 1429 dbSNP
rs1346165623 1436 dbSNP
rs1003462643 1444 dbSNP
rs1035343731 1454 dbSNP
rs1050157266 1456 dbSNP
rs1294733991 1457 dbSNP
rs780751991 1458 dbSNP
rs1012476804 1462 dbSNP
rs1008528029 1468 dbSNP
rs1163929096 1472 dbSNP
rs1298414035 1475 dbSNP
rs1348025604 1484 dbSNP
rs562922166 1496 dbSNP
rs962449688 1500 dbSNP
rs972434249 1501 dbSNP
rs892090922 1506 dbSNP
rs918255401 1531 dbSNP
rs769640689 1542 dbSNP
rs1010484119 1551 dbSNP
rs1021830564 1557 dbSNP
rs968895397 1561 dbSNP
rs1002043999 1566 dbSNP
rs200703088 1570 dbSNP
rs1397679395 1581 dbSNP
rs1212084524 1584 dbSNP
rs1314349134 1586 dbSNP
rs34469169 1595 dbSNP
rs1034411223 1597 dbSNP
rs960322903 1602 dbSNP
rs534040156 1603 dbSNP
rs372651332 1606 dbSNP
rs1294029257 1614 dbSNP
rs1214558388 1617 dbSNP
rs560289855 1623 dbSNP
rs1278281014 1625 dbSNP
rs1401394820 1633 dbSNP
rs1279736168 1635 dbSNP
rs1311937857 1650 dbSNP
rs911459974 1655 dbSNP
rs772927063 1667 dbSNP
rs1168233050 1668 dbSNP
rs1227227556 1681 dbSNP
rs752278785 1683 dbSNP
rs775246237 1699 dbSNP
rs762895906 1700 dbSNP
rs1474325632 1702 dbSNP
rs1257037212 1705 dbSNP
rs1182712193 1707 dbSNP
rs1484434307 1712 dbSNP
rs907880554 1716 dbSNP
rs961971338 1720 dbSNP
rs1041782626 1721 dbSNP
rs1488169426 1723 dbSNP
rs1258085444 1741 dbSNP
rs1219905538 1747 dbSNP
rs1214674988 1748 dbSNP
rs527421864 1757 dbSNP
rs1292284630 1766 dbSNP
rs1265640439 1767 dbSNP
rs138940773 1775 dbSNP
rs1296255359 1782 dbSNP
rs1441333406 1784 dbSNP
rs770688210 1788 dbSNP
rs1181322703 1794 dbSNP
rs1411791955 1798 dbSNP
rs1172780343 1799 dbSNP
rs564097068 1801 dbSNP
rs986290147 1804 dbSNP
rs1012092048 1805 dbSNP
rs1016742938 1809 dbSNP
rs898295070 1816 dbSNP
rs993885954 1817 dbSNP
rs1458572415 1820 dbSNP
rs1240551152 1823 dbSNP
rs1299862605 1824 dbSNP
rs1212434053 1830 dbSNP
rs911612576 1835 dbSNP
rs531304417 1836 dbSNP
rs1244993846 1849 dbSNP
rs551272203 1853 dbSNP
rs1300549182 1854 dbSNP
rs770728190 1855 dbSNP
rs1052140044 1858 dbSNP
rs1377424964 1859 dbSNP
rs1333270069 1873 dbSNP
rs1438707944 1877 dbSNP
rs1230458724 1878 dbSNP
rs569409783 1888 dbSNP
rs1294204885 1889 dbSNP
rs34049466 1891 dbSNP
rs149398546 1893 dbSNP
rs548547552 1897 dbSNP
rs1459592927 1901 dbSNP
rs1362310450 1902 dbSNP
rs1158720563 1903 dbSNP
rs1440688055 1907 dbSNP
rs1382627282 1912 dbSNP
rs1192235895 1913 dbSNP
rs1468439547 1914 dbSNP
rs1316388695 1916 dbSNP
rs1018556717 1918 dbSNP
rs774521376 1921 dbSNP
rs892118679 1922 dbSNP
rs1239051088 1932 dbSNP
rs1354143220 1940 dbSNP
rs1311190169 1947 dbSNP
rs144806008 1953 dbSNP
rs914744180 1959 dbSNP
rs534062619 1969 dbSNP
rs1302019828 1971 dbSNP
rs558606452 1974 dbSNP
rs570536862 1976 dbSNP
rs1173507336 1980 dbSNP
rs1382961007 1985 dbSNP
rs1043300646 1986 dbSNP
rs1420547413 1987 dbSNP
rs1362786881 1988 dbSNP
rs1172190032 1991 dbSNP
rs1454188394 1999 dbSNP
rs1378689252 2006 dbSNP
rs1484294255 2009 dbSNP
rs1201711223 2015 dbSNP
rs767614222 2021 dbSNP
rs1184072849 2024 dbSNP
rs1237468074 2026 dbSNP
rs1001670280 2027 dbSNP
rs76580542 2034 dbSNP
rs1344081066 2036 dbSNP
rs1256506297 2042 dbSNP
rs977544759 2046 dbSNP
rs556423230 2060 dbSNP
rs928694703 2072 dbSNP
rs571049163 2074 dbSNP
rs1408520850 2078 dbSNP
rs1414241210 2080 dbSNP
rs760912225 2081 dbSNP
rs1014287529 2083 dbSNP
rs1014899684 2085 dbSNP
rs190102331 2086 dbSNP
rs370997749 2097 dbSNP
rs1038217438 2098 dbSNP
rs1185409649 2102 dbSNP
rs879650135 2104 dbSNP
rs1376771954 2108 dbSNP
rs1027535946 2113 dbSNP
rs1279077279 2114 dbSNP
rs1202056437 2115 dbSNP
rs1337398383 2120 dbSNP
rs1445301382 2127 dbSNP
rs953344522 2141 dbSNP
rs1351853918 2149 dbSNP
rs542095013 2152 dbSNP
rs1447657287 2155 dbSNP
rs1341375746 2162 dbSNP
rs911713232 2163 dbSNP
rs1390116036 2166 dbSNP
rs1400249354 2171 dbSNP
rs1172061413 2172 dbSNP
rs1465667982 2175 dbSNP
rs1425234600 2178 dbSNP
rs944496497 2181 dbSNP
rs181237464 2182 dbSNP
rs11071804 2183 dbSNP
rs556208200 2186 dbSNP
rs1435907899 2190 dbSNP
rs946341667 2197 dbSNP
rs1199259037 2199 dbSNP
rs1018374350 2210 dbSNP
rs1271353146 2211 dbSNP
rs1043330801 2212 dbSNP
rs1257576239 2216 dbSNP
rs904738017 2220 dbSNP
rs1401282434 2222 dbSNP
rs1456380237 2225 dbSNP
rs937580315 2229 dbSNP
rs545935875 2239 dbSNP
rs763246737 2240 dbSNP
rs1449660748 2249 dbSNP
rs564135688 2251 dbSNP
rs1014940614 2252 dbSNP
rs1189053909 2260 dbSNP
rs1021713097 2263 dbSNP
rs897835527 2263 dbSNP
rs994764231 2264 dbSNP
rs977982315 2267 dbSNP
rs186214112 2273 dbSNP
rs543004386 2276 dbSNP
rs1169336211 2286 dbSNP
rs561722212 2291 dbSNP
rs1251165844 2299 dbSNP
rs1220961346 2301 dbSNP
rs915906687 2321 dbSNP
rs1464461281 2322 dbSNP
rs1203670004 2323 dbSNP
rs148165180 2342 dbSNP
rs1310469106 2349 dbSNP
rs1038289249 2352 dbSNP
rs1369474798 2354 dbSNP
rs1274817466 2359 dbSNP
rs919824353 2362 dbSNP
rs1350023169 2363 dbSNP
rs965840367 2364 dbSNP
rs576028540 2366 dbSNP
rs1325110982 2371 dbSNP
rs1417485684 2387 dbSNP
rs1359595511 2388 dbSNP
rs1159048984 2390 dbSNP
rs548848938 2391 dbSNP
rs1336674354 2403 dbSNP
rs929839823 2404 dbSNP
rs1047350705 2405 dbSNP
rs750915566 2406 dbSNP
rs1008394422 2417 dbSNP
rs913614668 2424 dbSNP
rs1191232974 2426 dbSNP
rs1347612337 2429 dbSNP
rs1224410602 2431 dbSNP
rs1488100950 2432 dbSNP
rs967712577 2435 dbSNP
rs1219214031 2437 dbSNP
rs979153831 2439 dbSNP
rs754501784 2454 dbSNP
rs566754071 2455 dbSNP
rs1056435120 2459 dbSNP
rs780673086 2460 dbSNP
rs1397695008 2461 dbSNP
rs1339477640 2464 dbSNP
rs527853737 2470 dbSNP
rs917434906 2476 dbSNP
rs1227140169 2478 dbSNP
rs1421260649 2485 dbSNP
rs1273659202 2487 dbSNP
rs545090279 2492 dbSNP
rs1021916619 2494 dbSNP
rs1036415724 2505 dbSNP
rs1427300630 2515 dbSNP
rs1168666044 2520 dbSNP
rs1477562094 2524 dbSNP
rs1219072588 2531 dbSNP
rs74019280 2533 dbSNP
rs999094308 2535 dbSNP
rs1482479528 2536 dbSNP
rs755707803 2539 dbSNP
rs538331612 2540 dbSNP
rs960201855 2547 dbSNP
rs527973046 2551 dbSNP
rs1280077528 2554 dbSNP
rs556321464 2558 dbSNP
rs1316805635 2566 dbSNP
rs915992898 2576 dbSNP
rs1019254299 2581 dbSNP
rs1376611192 2584 dbSNP
rs965870084 2591 dbSNP
rs1302071833 2595 dbSNP
rs963370872 2595 dbSNP
rs1360795702 2617 dbSNP
rs1397794474 2621 dbSNP
rs777572171 2625 dbSNP
rs973362650 2627 dbSNP
rs919229254 2639 dbSNP
rs1321969506 2640 dbSNP
rs1424512212 2642 dbSNP
rs568425064 2643 dbSNP
rs1422300978 2650 dbSNP
rs1413461180 2652 dbSNP
rs71396429 2653 dbSNP
rs929911860 2658 dbSNP
rs1046934501 2661 dbSNP
rs749047116 2683 dbSNP
rs1198634072 2693 dbSNP
rs1456926421 2698 dbSNP
rs1020790955 2705 dbSNP
rs190326198 2707 dbSNP
rs967827167 2712 dbSNP
rs538760964 2716 dbSNP
rs926335689 2717 dbSNP
rs1355551867 2721 dbSNP
rs899573676 2726 dbSNP
rs1011303663 2729 dbSNP
rs959266992 2731 dbSNP
rs1293586480 2766 dbSNP
rs1456544346 2769 dbSNP
rs1349481564 2770 dbSNP
rs1165806792 2771 dbSNP
rs1425910802 2771 dbSNP
rs991761091 2774 dbSNP
rs917467825 2778 dbSNP
rs1378925313 2780 dbSNP
rs1178493560 2785 dbSNP
rs1490460816 2800 dbSNP
rs1215375883 2801 dbSNP
rs770730362 2804 dbSNP
rs1036529961 2805 dbSNP
rs1489088535 2808 dbSNP
rs999522051 2809 dbSNP
rs1221939256 2810 dbSNP
rs919409069 2811 dbSNP
rs930757838 2835 dbSNP
rs113216323 2846 dbSNP
rs745807045 2852 dbSNP
rs1007933599 2864 dbSNP
rs772111852 2866 dbSNP
rs1040299111 2874 dbSNP
rs1161986892 2879 dbSNP
rs901794667 2881 dbSNP
rs1023033581 2883 dbSNP
rs1294335295 2884 dbSNP
rs1009483343 2896 dbSNP
rs760626625 2903 dbSNP
rs1358958091 2905 dbSNP
rs1020821965 2909 dbSNP
rs138923939 2910 dbSNP
rs1382678891 2915 dbSNP
rs973434815 2918 dbSNP
rs967858213 2921 dbSNP
rs1384203780 2931 dbSNP
rs1319052690 2932 dbSNP
rs1339960584 2934 dbSNP
rs1283566076 2938 dbSNP
rs1000631683 2951 dbSNP
rs1033821438 2956 dbSNP
rs564499417 2960 dbSNP
rs983136914 2966 dbSNP
rs1262402278 2980 dbSNP
rs1231064152 2988 dbSNP
rs1360133737 2992 dbSNP
rs1330526343 2996 dbSNP
rs1302086627 2997 dbSNP
rs778783514 3002 dbSNP
rs992271248 3003 dbSNP
rs760998653 3004 dbSNP
rs971646906 3005 dbSNP
rs571747609 3012 dbSNP
rs1400979040 3016 dbSNP
rs1362922727 3017 dbSNP
rs972276925 3018 dbSNP
rs1283700021 3022 dbSNP
rs112306400 3034 dbSNP
rs182098817 3040 dbSNP
rs930784165 3048 dbSNP
rs1254788073 3053 dbSNP
rs1440230608 3054 dbSNP
rs984896431 3055 dbSNP
rs910591638 3057 dbSNP
rs1245488466 3063 dbSNP
rs1488489481 3081 dbSNP
rs1042794704 3086 dbSNP
rs377588372 3090 dbSNP
rs1344245486 3091 dbSNP
rs1256559898 3096 dbSNP
rs1445810730 3101 dbSNP
rs943458053 3107 dbSNP
rs1057510498 3108 dbSNP
rs1328510568 3115 dbSNP
rs1455488650 3122 dbSNP
rs374239087 3126 dbSNP
rs1332638431 3127 dbSNP
rs1395920413 3130 dbSNP
rs1403492909 3132 dbSNP
rs1159397330 3139 dbSNP
rs1305157914 3140 dbSNP
rs545974723 3145 dbSNP
rs1470660820 3151 dbSNP
rs1420920250 3152 dbSNP
rs1401526173 3153 dbSNP
rs1040436665 3163 dbSNP
rs1169432670 3164 dbSNP
rs1477950803 3167 dbSNP
rs553565624 3168 dbSNP
rs1374532302 3178 dbSNP
rs1185180751 3182 dbSNP
rs896056115 3189 dbSNP
rs1013555361 3198 dbSNP
rs945302223 3199 dbSNP
rs576245353 3201 dbSNP
rs1219431398 3203 dbSNP
rs899298367 3204 dbSNP
rs1282686099 3208 dbSNP
rs946376035 3210 dbSNP
rs1341502957 3212 dbSNP
rs1042297743 3226 dbSNP
rs903704684 3227 dbSNP
rs1445214926 3241 dbSNP
rs1026346050 3244 dbSNP
rs1330120081 3245 dbSNP
rs1410141658 3246 dbSNP
rs1239268819 3248 dbSNP
rs555294052 3262 dbSNP
rs1001076487 3272 dbSNP
rs1472341130 3279 dbSNP
rs1342504656 3281 dbSNP
rs1204986599 3288 dbSNP
rs1033512081 3291 dbSNP
rs543500195 3292 dbSNP
rs561557090 3298 dbSNP
rs1237601773 3299 dbSNP
rs185341746 3300 dbSNP
rs975290739 3305 dbSNP
rs1209535796 3306 dbSNP
rs1287972700 3306 dbSNP
rs961000834 3307 dbSNP
rs1357410836 3309 dbSNP
rs561272532 3315 dbSNP
rs1238548299 3317 dbSNP
rs542172130 3323 dbSNP
rs947196651 3326 dbSNP
rs1442286333 3328 dbSNP
rs1337085867 3341 dbSNP
rs1421272294 3342 dbSNP
rs560383937 3346 dbSNP
rs1026485469 3348 dbSNP
rs1165278490 3360 dbSNP
rs73454996 3363 dbSNP
rs147232159 3374 dbSNP
rs1056812362 3378 dbSNP
rs775066878 3383 dbSNP
rs1043406436 3392 dbSNP
rs895446649 3393 dbSNP
rs530296409 3396 dbSNP
rs868482020 3398 dbSNP
rs1178658386 3428 dbSNP
rs140720939 3429 dbSNP
rs1464973408 3435 dbSNP
rs1352145687 3448 dbSNP
rs1329269993 3455 dbSNP
rs762218535 3463 dbSNP
rs1345718981 3466 dbSNP
rs1304638337 3474 dbSNP
rs72742982 3475 dbSNP
rs1391740248 3476 dbSNP
rs994961160 3476 dbSNP
rs1159654085 3478 dbSNP
rs1300384185 3479 dbSNP
rs1328994316 3481 dbSNP
rs1402384942 3482 dbSNP
rs945333197 3484 dbSNP
rs1423090387 3486 dbSNP
rs1172098103 3490 dbSNP
rs750761827 3503 dbSNP
rs1480826655 3520 dbSNP
rs1271289236 3523 dbSNP
rs758870332 3526 dbSNP
rs111427628 3535 dbSNP
rs752294220 3535 dbSNP
rs1009376086 3538 dbSNP
rs1218501153 3543 dbSNP
rs1198515623 3544 dbSNP
rs1042328522 3550 dbSNP
rs903805298 3552 dbSNP
rs1250103236 3555 dbSNP
rs4402501 3565 dbSNP
rs1284797691 3574 dbSNP
rs1216415055 3580 dbSNP
rs1055393135 3591 dbSNP
rs894967091 3593 dbSNP
rs1196740694 3600 dbSNP
rs1339532431 3601 dbSNP
rs1013303093 3602 dbSNP
rs752157115 3603 dbSNP
rs896829372 3618 dbSNP
rs1201861240 3627 dbSNP
rs1028241284 3629 dbSNP
rs1470336636 3638 dbSNP
rs373366704 3639 dbSNP
rs1431548756 3646 dbSNP
rs568380433 3647 dbSNP
rs1477631531 3649 dbSNP
rs1420622863 3654 dbSNP
rs1188626187 3660 dbSNP
rs978578251 3662 dbSNP
rs924411839 3665 dbSNP
rs1204930397 3669 dbSNP
rs535814558 3674 dbSNP
rs1461323385 3675 dbSNP
rs1462496077 3676 dbSNP
rs993761463 3681 dbSNP
rs1196310786 3682 dbSNP
rs768595098 3690 dbSNP
rs1295897834 3692 dbSNP
rs992947331 3693 dbSNP
rs547717465 3695 dbSNP
rs952436404 3700 dbSNP
rs1453304985 3701 dbSNP
rs532456735 3705 dbSNP
rs948380651 3706 dbSNP
rs190990473 3709 dbSNP
rs1339496522 3717 dbSNP
rs1422433486 3721 dbSNP
rs1018216321 3729 dbSNP
rs1184682330 3737 dbSNP
rs1297181406 3738 dbSNP
rs1446998548 3743 dbSNP
rs1244398414 3746 dbSNP
rs964877285 3759 dbSNP
rs930870563 3761 dbSNP
rs867305259 3763 dbSNP
rs1251514604 3767 dbSNP
rs976180809 3768 dbSNP
rs1047912928 3770 dbSNP
rs1309765261 3771 dbSNP
rs1290787551 3772 dbSNP
rs1228805705 3778 dbSNP
rs1246573995 3778 dbSNP
rs1384870739 3778 dbSNP
rs886569282 3778 dbSNP
rs923309315 3779 dbSNP
rs1349609642 3784 dbSNP
rs1456592338 3784 dbSNP
rs966779394 3784 dbSNP
rs1164641897 3785 dbSNP
rs978129903 3786 dbSNP
rs1224951902 3788 dbSNP
rs1269846692 3789 dbSNP
rs1250632660 3790 dbSNP
rs1178526533 3795 dbSNP
rs996160911 3797 dbSNP
rs1222928500 3799 dbSNP
rs1267785910 3799 dbSNP
rs1028273834 3803 dbSNP
rs1421813328 3811 dbSNP
rs1238254052 3813 dbSNP
rs1317529677 3818 dbSNP
rs968636194 3821 dbSNP
rs1000090437 3827 dbSNP
rs1031504745 3833 dbSNP
rs956031589 3839 dbSNP
rs925291690 3850 dbSNP
rs1407131500 3852 dbSNP
rs992624458 3853 dbSNP
rs1383111025 3855 dbSNP
rs1158499376 3856 dbSNP
rs1454784644 3856 dbSNP
rs1363831954 3871 dbSNP
rs916982040 3875 dbSNP
rs1431004874 3876 dbSNP
rs1428152728 3878 dbSNP
rs1199786232 3879 dbSNP
rs1426291484 3883 dbSNP
rs1164020500 3890 dbSNP
rs1490761197 3900 dbSNP
rs969717297 3903 dbSNP
rs979723543 3906 dbSNP
rs936615374 3910 dbSNP
rs527534854 3911 dbSNP
rs552652366 3915 dbSNP
rs1231127487 3930 dbSNP
rs1322991842 3950 dbSNP
rs116529688 3951 dbSNP
rs1225586326 3956 dbSNP
rs1362042982 3957 dbSNP
rs766760590 3958 dbSNP
rs1338839047 3964 dbSNP
rs1383223524 3966 dbSNP
rs1318110390 3969 dbSNP
rs1312658083 3970 dbSNP
rs1383169575 3972 dbSNP
rs1387752105 3973 dbSNP
rs1357993024 3979 dbSNP
rs1464103824 3983 dbSNP
rs916419408 3984 dbSNP
rs1427999891 3994 dbSNP
rs1176636676 3998 dbSNP
rs1048413081 4000 dbSNP
rs565685061 4001 dbSNP
rs1421151409 4003 dbSNP
rs1192160866 4005 dbSNP
rs1428947423 4007 dbSNP
rs1263745603 4008 dbSNP
rs1198725152 4010 dbSNP
rs1460875558 4017 dbSNP
rs1263846024 4032 dbSNP
rs1205765116 4038 dbSNP
rs1248589085 4048 dbSNP
rs949182436 4049 dbSNP
rs1316261954 4051 dbSNP
rs140006707 4052 dbSNP
rs1228601023 4054 dbSNP
rs896943506 4055 dbSNP
rs993874695 4057 dbSNP
rs1311127592 4060 dbSNP
rs1048557847 4062 dbSNP
rs1336850786 4065 dbSNP
rs149715072 4066 dbSNP
rs536779757 4069 dbSNP
rs1213930815 4075 dbSNP
rs1167020601 4076 dbSNP
rs1243852650 4108 dbSNP
rs1462300108 4112 dbSNP
rs1374588628 4120 dbSNP
rs1185255099 4121 dbSNP
rs1486253095 4121 dbSNP
rs1443967866 4126 dbSNP
rs1243717889 4127 dbSNP
rs1006895171 4128 dbSNP
rs184075106 4131 dbSNP
rs1241162815 4139 dbSNP
rs1272559643 4141 dbSNP
rs996234298 4141 dbSNP
rs1196610378 4142 dbSNP
rs965246492 4148 dbSNP
rs1264079399 4150 dbSNP
rs1446443861 4161 dbSNP
rs997648135 4166 dbSNP
rs748948665 4170 dbSNP
rs573575874 4179 dbSNP
rs778766069 4180 dbSNP
rs540972180 4192 dbSNP
rs560420574 4197 dbSNP
rs1398300932 4203 dbSNP
rs1031996386 4205 dbSNP
rs1385772536 4228 dbSNP
rs1165468873 4237 dbSNP
rs1437836503 4241 dbSNP
rs1345211231 4242 dbSNP
rs958041681 4243 dbSNP
rs991148457 4255 dbSNP
rs1182746742 4257 dbSNP
rs1014483513 4260 dbSNP
rs916467627 4264 dbSNP
rs949296868 4265 dbSNP
rs745804713 4267 dbSNP
rs1381224028 4269 dbSNP
rs1222183119 4277 dbSNP
rs1455111375 4290 dbSNP
rs188562956 4298 dbSNP
rs1316098874 4301 dbSNP
rs918400781 4305 dbSNP
rs1294580856 4307 dbSNP
rs111677338 4308 dbSNP
rs1238615691 4310 dbSNP
rs879354812 4318 dbSNP
rs1376635827 4322 dbSNP
rs1278468252 4325 dbSNP
rs1442351925 4331 dbSNP
rs771994037 4338 dbSNP
rs546069633 4339 dbSNP
rs55729175 4345 dbSNP
rs775742950 4347 dbSNP
rs1027287477 4353 dbSNP
rs951709746 4354 dbSNP
rs1006515672 4356 dbSNP
rs56016689 4357 dbSNP
rs1039699744 4360 dbSNP
rs879540487 4363 dbSNP
rs747124944 4364 dbSNP
rs1427442975 4370 dbSNP
rs908101956 4373 dbSNP
rs1490595992 4375 dbSNP
rs944923232 4380 dbSNP
rs1215023891 4384 dbSNP
rs900795744 4410 dbSNP
rs1446963250 4420 dbSNP
rs1285635189 4428 dbSNP
rs976670069 4436 dbSNP
rs1267566212 4437 dbSNP
rs1352301953 4448 dbSNP
rs1280900860 4458 dbSNP
rs1222542945 4459 dbSNP
rs1345859909 4461 dbSNP
rs997752211 4465 dbSNP
rs932056096 4470 dbSNP
rs1030535487 4474 dbSNP
rs1237293608 4480 dbSNP
rs1344507283 4487 dbSNP
rs902657150 4490 dbSNP
rs1402515851 4492 dbSNP
rs1404004802 4497 dbSNP
rs1178775847 4498 dbSNP
rs1408229645 4509 dbSNP
rs1432307729 4512 dbSNP
rs1000037287 4516 dbSNP
rs192839578 4521 dbSNP
rs768831495 4524 dbSNP
rs1218565636 4525 dbSNP
rs1475325793 4525 dbSNP
rs183767808 4525 dbSNP
rs1407680311 4527 dbSNP
rs1471204936 4529 dbSNP
rs1053064112 4534 dbSNP
rs1337995923 4534 dbSNP
rs1284854845 4536 dbSNP
rs145586362 4541 dbSNP
rs376629900 4542 dbSNP
rs1270627526 4543 dbSNP
rs186843530 4550 dbSNP
rs1336197426 4552 dbSNP
rs1380611499 4552 dbSNP
rs1024097451 4553 dbSNP
rs970642168 4555 dbSNP
rs191732231 4559 dbSNP
rs918432057 4568 dbSNP
rs929785924 4572 dbSNP
rs984278987 4573 dbSNP
rs909596828 4574 dbSNP
rs942434172 4576 dbSNP
rs56251795 4590 dbSNP
rs1420688473 4592 dbSNP
rs529280623 4594 dbSNP
rs1039396774 4595 dbSNP
rs773429295 4599 dbSNP
rs900828299 4602 dbSNP
rs1182424264 4628 dbSNP
rs1243108475 4628 dbSNP
rs1027359074 4630 dbSNP
rs951737916 4635 dbSNP
rs1202012852 4637 dbSNP
rs933574793 4645 dbSNP
rs762088426 4648 dbSNP
rs902686515 4650 dbSNP
rs999666463 4672 dbSNP
rs1314367170 4673 dbSNP
rs1453466443 4676 dbSNP
rs770055481 4686 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggugagaagacugagguuCAGGUCa 5'
                            |||||| 
Target 5' ------------uccaguGUCCAGa 3'
 		1 - 13
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000326648.3 | 3UTR | UCCAGUGUCCAGACUACCUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000326648.3 | 3UTR | UCCAGUGUCCAGACUACCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA -0.367 0 -0.366 0 83 Click to see details
LIHC -0.304 0.02 -0.162 0.13 49 Click to see details
HNSC -0.213 0.09 -0.220 0.08 42 Click to see details
PCPG 0.959 0.09 1.000 0.5 3 Click to see details
CHOL 0.473 0.1 0.667 0.02 9 Click to see details
LUSC -0.21 0.1 -0.340 0.02 38 Click to see details
CESC -0.941 0.11 -1.000 0.5 3 Click to see details
STAD -0.155 0.2 -0.047 0.4 32 Click to see details
PAAD -0.568 0.22 -0.800 0.1 4 Click to see details
KIRC -0.096 0.22 -0.146 0.12 67 Click to see details
PRAD 0.104 0.24 0.035 0.4 50 Click to see details
KICH -0.119 0.29 -0.038 0.43 25 Click to see details
UCEC -0.11 0.33 -0.135 0.29 19 Click to see details
ESCA 0.144 0.34 0.164 0.31 11 Click to see details
THCA 0.05 0.35 0.064 0.32 59 Click to see details
LUAD -0.117 0.36 -0.441 0.08 12 Click to see details
BLCA 0.088 0.36 0.212 0.2 18 Click to see details
KIRP 0.016 0.47 -0.177 0.18 29 Click to see details
KIRP 0.016 0.47 -0.177 0.18 29 Click to see details
32 hsa-miR-378c Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT052829 DDX17 DEAD-box helicase 17 1 1
MIRT052830 RPS7 ribosomal protein S7 1 1
MIRT052831 SEC31A SEC31 homolog A, COPII coat complex component 1 1
MIRT052832 KDM8 lysine demethylase 8 1 1
MIRT052833 ANO4 anoctamin 4 1 1
MIRT463104 ZNF609 zinc finger protein 609 2 2
MIRT469375 REST RE1 silencing transcription factor 2 6
MIRT495444 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT513609 VPS37B VPS37B, ESCRT-I subunit 2 2
MIRT520417 TXNL1 thioredoxin like 1 2 4
MIRT525114 PRKD2 protein kinase D2 2 2
MIRT525982 SPA17 sperm autoantigenic protein 17 2 2
MIRT527005 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT529218 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT529838 ARGFX arginine-fifty homeobox 2 2
MIRT532302 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT537579 ESYT2 extended synaptotagmin 2 2 2
MIRT543143 AKT1 AKT serine/threonine kinase 1 2 2
MIRT554927 RAP1B RAP1B, member of RAS oncogene family 2 2
MIRT564973 WTAP WT1 associated protein 2 2
MIRT570119 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT652737 TGFB2 transforming growth factor beta 2 2 2
MIRT655951 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT656000 MYRF myelin regulatory factor 2 2
MIRT684878 P4HB prolyl 4-hydroxylase subunit beta 2 2
MIRT692972 LGSN lengsin, lens protein with glutamine synthetase domain 2 2
MIRT693740 ACACA acetyl-CoA carboxylase alpha 2 2
MIRT710994 PPARGC1B PPARG coactivator 1 beta 2 2
MIRT712242 RCC2 regulator of chromosome condensation 2 2 2
MIRT718605 DCTPP1 dCTP pyrophosphatase 1 2 2
MIRT723502 WDR33 WD repeat domain 33 2 2
MIRT725450 HIPK3 homeodomain interacting protein kinase 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-378c Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7, T47D)
hsa-mir-378c Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (BGC823)
hsa-miR-378c Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (SW1990)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (SW1990)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-378c Aromatase Inhibitor sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-378c Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia tissue
hsa-miR-378c Palbociclib 5330286 NSC758247 approved sensitive High Breast Cancer cell line (T47D)
hsa-miR-378c Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer tissue
hsa-miR-378c Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer tissue
hsa-mir-378c Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-378c Androstenedione+Anastrozole sensitive cell line (MCF-7)
hsa-mir-378c Tamoxifen 2733525 NSC180973 approved resistant cell line (MCF7)
hsa-mir-378c Cisplatin 5460033 NSC119875 approved resistant cell line (BGC-823)
hsa-miR-378c Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-378c Palbociclib 5330286 NSC758247 approved sensitive tissue (breast cancer)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-378c Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-378c Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-378c Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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