miRTarBase - #MIRT463686


—
pre-miRNA Information
pre-miRNA hsa-mir-2681   
Genomic Coordinates chr13: 101967642 - 101967746
Description Homo sapiens miR-2681 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2681-3p
Sequence 61| UAUCAUGGAGUUGGUAAAGCAC |82
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs893763121 2 dbSNP
rs1239476423 8 dbSNP
rs1304343828 10 dbSNP
rs1347238327 15 dbSNP
rs1217911872 19 dbSNP
Putative Targets

Gene Information
Gene Symbol YWHAZ   
Synonyms 14-3-3-zeta, HEL-S-3, HEL-S-93, HEL4, KCIP-1, YWHAD
Description tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
Transcript NM_001135699   
Other Transcripts NM_001135700 , NM_001135701 , NM_001135702 , NM_003406 , NM_145690   
Expression
Putative miRNA Targets on YWHAZ
3'UTR of YWHAZ
(miRNA target sites are highlighted)		 
>YWHAZ|NM_001135699|3'UTR
   1 CCGGCCTTCCAACTTTTGTCTGCCTCATTCTAAAATTTACACAGTAGACCATTTGTCATCCATGCTGTCCCACAAATAGT
  81 TTTTTGTTTACGATTTATGACAGGTTTATGTTACTTCTATTTGAATTTCTATATTTCCCATGTGGTTTTTATGTTTAATA
 161 TTAGGGGAGTAGAGCCAGTTAACATTTAGGGAGTTATCTGTTTTCATCTTGAGGTGGCCAATATGGGGATGTGGAATTTT
 241 TATACAAGTTATAAGTGTTTGGCATAGTACTTTTGGTACATTGTGGCTTCAAAAGGGCCAGTGTAAAACTGCTTCCATGT
 321 CTAAGCAAAGAAAACTGCCTACATACTGGTTTGTCCTGGCGGGGAATAAAAGGGATCATTGGTTCCAGTCACAGGTGTAG
 401 TAATTGTGGGTACTTTAAGGTTTGGAGCACTTACAAGGCTGTGGTAGAATCATACCCCATGGATACCACATATTAAACCA
 481 TGTATATCTGTGGAATACTCAATGTGTACACCTTTGACTACAGCTGCAGAAGTGTTCCTTTAGACAAAGTTGTGACCCAT
 561 TTTACTCTGGATAAGGGCAGAAACGGTTCACATTCCATTATTTGTAAAGTTACCTGCTGTTAGCTTTCATTATTTTTGCT
 641 ACACTCATTTTATTTGTATTTAAATGTTTTAGGCAACCTAAGAACAAATGTAAAAGTAAAGATGCAGGAAAAATGAATTG
 721 CTTGGTATTCATTACTTCATGTATATCAAGCACAGCAGTAAAACAAAAACCCATGTATTTAACTTTTTTTTAGGATTTTT
 801 GCTTTTGTGATTTTTTTTTTTTTGATACTTGCCTAACATGCATGTGCTGTAAAAATAGTTAACAGGGAAATAACTTGAGA
 881 TGATGGCTAGCTTTGTTTAATGTCTTATGAAATTTTCATGAACAATCCAAGCATAATTGTTAAGAACACGTGTATTAAAT
 961 TCATGTAAGTGGAATAAAAGTTTTATGAATGGACTTTTCAACTACTTTCTCTACAGCTTTTCATGTAAATTAGTCTTGGT
1041 TCTGAAACTTCTCTAAAGGAAATTGTACATTTTTTGAAATTTATTCCTTATTCCCTCTTGGCAGCTAATGGGCTCTTACC
1121 AAGTTTAAACACAAAATTTATCATAACAAAAATACTACTAATATAACTACTGTTTCCATGTCCCATGATCCCCTCTCTTC
1201 CTCCCCACCCTGAAAAAAATGAGTTCCTATTTTTTCTGGGAGAGGGGGGGATTGATTAGAAAAAAATGTAGTGTGTTCCA
1281 TTTAAAATTTTGGCATATGGCATTTTCTAACTTAGGAAGCCACAATGTTCTTGGCCCATCATGACATTGGGTAGCATTAA
1361 CTGTAAGTTTTGTGCTTCCAAATCACTTTTTGGTTTTTAAGAATTTCTTGATACTCTTATAGCCTGCCTTCAATTTTGAT
1441 CCTTTATTCTTTCTATTTGTCAGGTGCACAAGATTACCTTCCTGTTTTAGCCTTCTGTCTTGTCACCAACCATTCTTACT
1521 TGGTGGCCATGTACTTGGAAAAAGGCCGCATGATCTTTCTGGCTCCACTCAGTGTCTAAGGCACCCTGCTTCCTTTGCTT
1601 GCATCCCACAGACTATTTCCCTCATCCTATTTACTGCAGCAAATCTCTCCTTAGTTGATGAGACTGTGTTTATCTCCCTT
1681 TAAAACCCTACCTATCCTGAATGGTCTGTCATTGTCTGCCTTTAAAATCCTTCCTCTTTCTTCCTCCTCTATTCTCTAAA
1761 TAATGATGGGGCTAAGTTATACCCAAAGCTCACTTTACAAAATATTTCCTCAGTACTTTGCAGAAAACACCAAACAAAAA
1841 TGCCATTTTAAAAAAGGTGTATTTTTTCTTTTAGAATGTAAGCTCCTCAAGAGCAGGGACAATGTTTTCTGTATGTTCTA
1921 TTGTGCCTAGTACACTGTAAATGCTCAATAAATATTGATGATGGGAGGCAGTGAGTCTTGATGATAAGGGTGAGAAACTG
2001 AAATCCCAAACACTGTTTTGTTGCTTGTTTTATTATGACCTCAGATTAAATTGGGAAATATTGGCCCTTTTGAATAATTG
2081 TCCCAAATATTACATTCAAATAAAAGTGCAATGGAGAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cacGA-AAUGGU-UGAGGUACUAu 5'
             || || ||| :: ||||||| 
Target 5' ctaCTGTTTCCATGTCCCATGATc 3'
 1167 - 1190 155.00 -12.10
2 
miRNA  3' cacgAAAUGGUUGAGGUACUAu 5'
              |||::||  |||||| | 
Target 5' accaTTTGTCA--TCCATGCTg 3'
 48 - 67 130.00 -9.80
3 
miRNA  3' caCGAAAUGGUUGAGGUACUAu 5'
            | || ||  |:||||| || 
Target 5' acGGTTCAC--ATTCCATTATt 3'
 583 - 602 128.00 -7.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30468458 10 COSMIC
COSN31601405 10 COSMIC
COSN26670221 12 COSMIC
COSN30525436 49 COSMIC
COSN30146438 60 COSMIC
COSN30450811 71 COSMIC
COSN26582077 92 COSMIC
COSN31540443 98 COSMIC
COSN26581834 105 COSMIC
COSN31547898 129 COSMIC
COSN30510760 136 COSMIC
COSN30040545 197 COSMIC
COSN21457005 208 COSMIC
COSN26561824 245 COSMIC
COSN26667553 255 COSMIC
COSN28775092 329 COSMIC
COSN30541067 342 COSMIC
COSN6901563 400 COSMIC
COSN31522381 410 COSMIC
COSN26666389 584 COSMIC
COSN28690079 641 COSMIC
COSN31568762 652 COSMIC
COSN31523986 769 COSMIC
COSN25948069 783 COSMIC
COSN30161468 908 COSMIC
COSN31490973 909 COSMIC
COSN31585474 914 COSMIC
COSN26585839 917 COSMIC
COSN31545926 919 COSMIC
COSN26581097 923 COSMIC
COSN21409619 1122 COSMIC
COSN30543585 1282 COSMIC
COSN8050938 1319 COSMIC
COSN28740909 1455 COSMIC
COSN30175544 1740 COSMIC
COSN30175543 1756 COSMIC
COSN30170722 1946 COSMIC
COSN4936315 1989 COSMIC
COSN8050937 2154 COSMIC
COSN27575925 2248 COSMIC
COSN31855054 2249 COSMIC
COSN27616205 2334 COSMIC
COSN9519532 2523 COSMIC
COSN19282438 2575 COSMIC
COSN6901562 2613 COSMIC
COSN24174021 2615 COSMIC
COSN22293856 2827 COSMIC
COSN27349458 2936 COSMIC
COSN22820052 3268 COSMIC
COSN5230151 3532 COSMIC
COSN27914160 3821 COSMIC
COSN25346742 3856 COSMIC
COSN20234160 4083 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs202185783 2 dbSNP
rs201849882 3 dbSNP
rs780150324 5 dbSNP
rs1272264854 6 dbSNP
rs758535439 9 dbSNP
rs1361414520 13 dbSNP
rs201110733 14 dbSNP
rs1272160449 16 dbSNP
rs560476770 21 dbSNP
rs1380063726 26 dbSNP
rs757472369 27 dbSNP
rs541647261 29 dbSNP
rs764328564 30 dbSNP
rs1327508868 38 dbSNP
rs1427029118 44 dbSNP
rs1371732940 51 dbSNP
rs775599297 51 dbSNP
rs1479100856 55 dbSNP
rs1173389880 79 dbSNP
rs752047964 79 dbSNP
rs11551354 86 dbSNP
rs1433014754 89 dbSNP
rs1171670101 91 dbSNP
rs1362433313 92 dbSNP
rs184148359 103 dbSNP
rs1317329463 104 dbSNP
rs752066360 109 dbSNP
rs1438098180 113 dbSNP
rs1303702127 114 dbSNP
rs1231499396 117 dbSNP
rs1406964795 117 dbSNP
rs925564740 119 dbSNP
rs562545470 131 dbSNP
rs1479586278 139 dbSNP
rs1428257897 140 dbSNP
rs975570220 141 dbSNP
rs1453689194 144 dbSNP
rs1430223290 151 dbSNP
rs1252673354 172 dbSNP
rs1452635674 174 dbSNP
rs1160576516 181 dbSNP
rs1381036469 188 dbSNP
rs942873639 188 dbSNP
rs1157945928 193 dbSNP
rs1406932544 197 dbSNP
rs376209416 197 dbSNP
rs1326137020 199 dbSNP
rs1204001238 200 dbSNP
rs1369835868 200 dbSNP
rs1461342063 205 dbSNP
rs766850750 208 dbSNP
rs1310750216 216 dbSNP
rs1335845638 218 dbSNP
rs1259551650 219 dbSNP
rs763268892 219 dbSNP
rs1201318026 221 dbSNP
rs1358895042 225 dbSNP
rs1214764138 229 dbSNP
rs1272750017 233 dbSNP
rs1322478031 239 dbSNP
rs145502947 242 dbSNP
rs1255760297 245 dbSNP
rs191185043 251 dbSNP
rs1180998214 260 dbSNP
rs1213647829 268 dbSNP
rs1362039048 270 dbSNP
rs1476045522 273 dbSNP
rs987264316 274 dbSNP
rs1393479401 280 dbSNP
rs1459494166 281 dbSNP
rs951506256 292 dbSNP
rs1396583978 296 dbSNP
rs1390373533 300 dbSNP
rs1305466220 310 dbSNP
rs558113602 312 dbSNP
rs1342825942 323 dbSNP
rs1050754251 326 dbSNP
rs1026030039 340 dbSNP
rs1293012714 341 dbSNP
rs1333169058 346 dbSNP
rs1200689439 348 dbSNP
rs1480343525 356 dbSNP
rs11551357 358 dbSNP
rs974142115 360 dbSNP
rs1382179782 361 dbSNP
rs1188585014 362 dbSNP
rs533571943 382 dbSNP
rs963260293 385 dbSNP
rs1383542515 394 dbSNP
rs186767787 395 dbSNP
rs1001976453 396 dbSNP
rs1461018048 409 dbSNP
rs1468425772 412 dbSNP
rs905011609 416 dbSNP
rs770025913 417 dbSNP
rs556367600 433 dbSNP
rs1480546471 434 dbSNP
rs1353953326 436 dbSNP
rs1220914999 439 dbSNP
rs1296522420 441 dbSNP
rs1307093517 458 dbSNP
rs1225543243 459 dbSNP
rs1486042134 462 dbSNP
rs11545396 467 dbSNP
rs1211502371 472 dbSNP
rs1024822898 480 dbSNP
rs1013718767 484 dbSNP
rs1256789460 484 dbSNP
rs1262210492 491 dbSNP
rs892218155 492 dbSNP
rs1052528357 493 dbSNP
rs1396294251 502 dbSNP
rs1434876386 503 dbSNP
rs1173550525 514 dbSNP
rs1192314893 517 dbSNP
rs1270830759 519 dbSNP
rs554084123 524 dbSNP
rs904090601 526 dbSNP
rs1040002020 529 dbSNP
rs942948451 541 dbSNP
rs1303763095 545 dbSNP
rs912692387 550 dbSNP
rs986992388 557 dbSNP
rs1250849092 558 dbSNP
rs879002446 561 dbSNP
rs140806054 564 dbSNP
rs1341850498 565 dbSNP
rs565389081 566 dbSNP
rs1249988678 568 dbSNP
rs918715841 575 dbSNP
rs1485426128 583 dbSNP
rs1184404634 584 dbSNP
rs974469560 584 dbSNP
rs962709599 585 dbSNP
rs551539483 587 dbSNP
rs1360876469 592 dbSNP
rs1317234676 594 dbSNP
rs1160470879 614 dbSNP
rs980628006 616 dbSNP
rs1452157222 618 dbSNP
rs1372051110 625 dbSNP
rs969286537 631 dbSNP
rs1025190009 632 dbSNP
rs1375637116 642 dbSNP
rs1013459575 645 dbSNP
rs1284957983 652 dbSNP
rs1316109861 653 dbSNP
rs570522311 656 dbSNP
rs758882848 663 dbSNP
rs1000514429 666 dbSNP
rs1212693606 674 dbSNP
rs1425211235 680 dbSNP
rs1387068397 681 dbSNP
rs903495322 700 dbSNP
rs1161100256 701 dbSNP
rs1443438359 708 dbSNP
rs1417670269 710 dbSNP
rs1039398730 713 dbSNP
rs531619161 725 dbSNP
rs891378705 726 dbSNP
rs1183464514 727 dbSNP
rs4003432 734 dbSNP
rs1324140929 735 dbSNP
rs1356354116 738 dbSNP
rs535786363 739 dbSNP
rs1051695009 740 dbSNP
rs930190713 741 dbSNP
rs568595016 744 dbSNP
rs1490649428 774 dbSNP
rs1226517895 783 dbSNP
rs1294834137 786 dbSNP
rs918650233 789 dbSNP
rs1038396886 792 dbSNP
rs1212672293 792 dbSNP
rs941462794 792 dbSNP
rs3921614 795 dbSNP
rs1244457744 800 dbSNP
rs1355665512 801 dbSNP
rs1280220449 803 dbSNP
rs1241451428 807 dbSNP
rs1479917794 808 dbSNP
rs868532393 809 dbSNP
rs770981479 810 dbSNP
rs866800209 810 dbSNP
rs58344290 811 dbSNP
rs1307160002 812 dbSNP
rs1190716650 813 dbSNP
rs1405377695 813 dbSNP
rs927263604 823 dbSNP
rs1417171338 824 dbSNP
rs142007434 824 dbSNP
rs369444018 824 dbSNP
rs866388383 824 dbSNP
rs869207861 824 dbSNP
rs1438097926 825 dbSNP
rs1367249394 827 dbSNP
rs1301166178 828 dbSNP
rs1423949563 831 dbSNP
rs1407992132 832 dbSNP
rs1159862346 835 dbSNP
rs1258903048 841 dbSNP
rs1485538366 844 dbSNP
rs1186308114 846 dbSNP
rs1244229241 857 dbSNP
rs1475829808 861 dbSNP
rs4085567 865 dbSNP
rs1167557496 866 dbSNP
rs1417453905 867 dbSNP
rs183659599 874 dbSNP
rs969709394 877 dbSNP
rs1298694232 882 dbSNP
rs1414124941 889 dbSNP
rs1362909318 890 dbSNP
rs1327994910 904 dbSNP
rs1269301049 908 dbSNP
rs917874228 908 dbSNP
rs1362386502 909 dbSNP
rs1827729 914 dbSNP
rs193223230 919 dbSNP
rs1281633967 923 dbSNP
rs956590334 924 dbSNP
rs1199269049 925 dbSNP
rs866960160 928 dbSNP
rs1271517435 933 dbSNP
rs1192725630 947 dbSNP
rs570983777 949 dbSNP
rs1000586295 950 dbSNP
rs1194295532 959 dbSNP
rs1285033938 962 dbSNP
rs1207025675 980 dbSNP
rs1433963781 984 dbSNP
rs1170747242 989 dbSNP
rs1017912493 997 dbSNP
rs1317171550 1000 dbSNP
rs1006598851 1001 dbSNP
rs1442694328 1009 dbSNP
rs552599903 1011 dbSNP
rs891361020 1013 dbSNP
rs1287922832 1015 dbSNP
rs1224379809 1017 dbSNP
rs1051375483 1030 dbSNP
rs1347098225 1038 dbSNP
rs749554133 1038 dbSNP
rs1281146206 1045 dbSNP
rs1435668683 1060 dbSNP
rs188798657 1060 dbSNP
rs1345774466 1061 dbSNP
rs1319690178 1070 dbSNP
rs1266658947 1080 dbSNP
rs1398489242 1080 dbSNP
rs1469951469 1091 dbSNP
rs1214568268 1093 dbSNP
rs1431580474 1109 dbSNP
rs1196653968 1124 dbSNP
rs1365516201 1131 dbSNP
rs183506990 1132 dbSNP
rs1157742733 1135 dbSNP
rs897295590 1140 dbSNP
rs1038511510 1148 dbSNP
rs1326244266 1150 dbSNP
rs941409449 1158 dbSNP
rs1384618714 1161 dbSNP
rs140382471 1163 dbSNP
rs1197790943 1174 dbSNP
rs1477978177 1177 dbSNP
rs1243242624 1185 dbSNP
rs1044368704 1191 dbSNP
rs548418297 1198 dbSNP
rs1445306432 1199 dbSNP
rs950107878 1206 dbSNP
rs917807812 1207 dbSNP
rs992064921 1219 dbSNP
rs1272852180 1220 dbSNP
rs1487534682 1220 dbSNP
rs1261007346 1224 dbSNP
rs1197673711 1226 dbSNP
rs754929245 1229 dbSNP
rs770949836 1236 dbSNP
rs1181387423 1237 dbSNP
rs1476096142 1244 dbSNP
rs923733216 1244 dbSNP
rs191755037 1245 dbSNP
rs552290985 1245 dbSNP
rs562576549 1246 dbSNP
rs1363748290 1248 dbSNP
rs1336820579 1251 dbSNP
rs1396610237 1257 dbSNP
rs1018067657 1258 dbSNP
rs1470746265 1262 dbSNP
rs1391254274 1265 dbSNP
rs1306793228 1267 dbSNP
rs985513748 1267 dbSNP
rs1174362589 1268 dbSNP
rs1415836556 1269 dbSNP
rs1320102636 1270 dbSNP
rs749382387 1272 dbSNP
rs1420699521 1282 dbSNP
rs1338835044 1283 dbSNP
rs1204328586 1286 dbSNP
rs542590378 1300 dbSNP
rs1255241347 1315 dbSNP
rs1474716258 1315 dbSNP
rs779319598 1319 dbSNP
rs56284211 1320 dbSNP
rs1184351514 1325 dbSNP
rs1172096479 1333 dbSNP
rs1373149923 1334 dbSNP
rs1428613940 1336 dbSNP
rs1167240688 1337 dbSNP
rs1377842024 1338 dbSNP
rs1462807245 1341 dbSNP
rs1241574857 1347 dbSNP
rs115295165 1361 dbSNP
rs1377455161 1365 dbSNP
rs1384075261 1369 dbSNP
rs1307808061 1371 dbSNP
rs1325904749 1379 dbSNP
rs1226322322 1383 dbSNP
rs187173723 1384 dbSNP
rs1211522296 1388 dbSNP
rs1212663101 1391 dbSNP
rs1393083530 1402 dbSNP
rs1482191772 1403 dbSNP
rs1187891831 1415 dbSNP
rs1262053417 1416 dbSNP
rs1341448521 1417 dbSNP
rs752347610 1418 dbSNP
rs1315114110 1419 dbSNP
rs1454159312 1420 dbSNP
rs1396388634 1422 dbSNP
rs1379984302 1432 dbSNP
rs756248525 1433 dbSNP
rs1017056646 1441 dbSNP
rs1355414637 1453 dbSNP
rs1005710212 1455 dbSNP
rs577607650 1455 dbSNP
rs1433193858 1463 dbSNP
rs1305643323 1464 dbSNP
rs1371821875 1466 dbSNP
rs1428368572 1470 dbSNP
rs1234924671 1475 dbSNP
rs1300577583 1478 dbSNP
rs1310196822 1481 dbSNP
rs1217728463 1486 dbSNP
rs11551356 1487 dbSNP
rs1164259044 1488 dbSNP
rs950197339 1489 dbSNP
rs564686645 1490 dbSNP
rs116414929 1494 dbSNP
rs1423728472 1502 dbSNP
rs751076085 1503 dbSNP
rs765881259 1504 dbSNP
rs1411745299 1509 dbSNP
rs1181440063 1513 dbSNP
rs1481082379 1519 dbSNP
rs762866086 1520 dbSNP
rs540828852 1526 dbSNP
rs572466390 1527 dbSNP
rs1202247653 1528 dbSNP
rs923891846 1531 dbSNP
rs1288689604 1537 dbSNP
rs1328234239 1544 dbSNP
rs1281729066 1547 dbSNP
rs979249623 1548 dbSNP
rs554273550 1550 dbSNP
rs946557747 1556 dbSNP
rs1220130976 1559 dbSNP
rs1244496559 1576 dbSNP
rs911077888 1583 dbSNP
rs1356571602 1584 dbSNP
rs1178283915 1586 dbSNP
rs1311397122 1599 dbSNP
rs1471848181 1619 dbSNP
rs1167344047 1621 dbSNP
rs1418900824 1626 dbSNP
rs146766382 1629 dbSNP
rs1162713495 1630 dbSNP
rs1356370282 1644 dbSNP
rs1375149158 1647 dbSNP
rs1234708345 1649 dbSNP
rs955310373 1653 dbSNP
rs1308636712 1662 dbSNP
rs4003437 1664 dbSNP
rs1300240514 1668 dbSNP
rs1408428758 1669 dbSNP
rs1370366192 1670 dbSNP
rs575049075 1672 dbSNP
rs1294934058 1674 dbSNP
rs1356545875 1676 dbSNP
rs765135393 1688 dbSNP
rs113114570 1689 dbSNP
rs1227395935 1696 dbSNP
rs1287044488 1696 dbSNP
rs556703474 1698 dbSNP
rs1029292355 1703 dbSNP
rs1427123493 1708 dbSNP
rs761634525 1710 dbSNP
rs1482265647 1712 dbSNP
rs1190452157 1714 dbSNP
rs1258691964 1715 dbSNP
rs1472551957 1718 dbSNP
rs1180347757 1729 dbSNP
rs972850772 1734 dbSNP
rs1410666942 1739 dbSNP
rs1164247156 1740 dbSNP
rs961600671 1740 dbSNP
rs538485217 1741 dbSNP
rs3956010 1744 dbSNP
rs1419878413 1750 dbSNP
rs1314414826 1751 dbSNP
rs182781718 1761 dbSNP
rs1017170650 1762 dbSNP
rs1446820781 1764 dbSNP
rs189790503 1764 dbSNP
rs906015816 1765 dbSNP
rs1023102210 1766 dbSNP
rs1273314135 1768 dbSNP
rs1062376 1772 dbSNP
rs1340607412 1773 dbSNP
rs1014304521 1779 dbSNP
rs1279708888 1780 dbSNP
rs1442262217 1780 dbSNP
rs895888747 1782 dbSNP
rs1472115754 1785 dbSNP
rs1475879835 1786 dbSNP
rs751321717 1790 dbSNP
rs1187964106 1791 dbSNP
rs1062382 1792 dbSNP
rs1388408225 1793 dbSNP
rs534287930 1796 dbSNP
rs4106220 1802 dbSNP
rs1269354523 1805 dbSNP
rs566842756 1805 dbSNP
rs548307222 1806 dbSNP
rs529984551 1807 dbSNP
rs562666808 1808 dbSNP
rs527327647 1810 dbSNP
rs1224545431 1811 dbSNP
rs1384923888 1816 dbSNP
rs1402639000 1819 dbSNP
rs1413740918 1822 dbSNP
rs1331766013 1825 dbSNP
rs1053121731 1830 dbSNP
rs999294449 1831 dbSNP
rs1264336812 1840 dbSNP
rs1296142370 1845 dbSNP
rs1362416023 1849 dbSNP
rs1237121473 1850 dbSNP
rs1276027837 1851 dbSNP
rs1178310468 1854 dbSNP
rs1215948470 1859 dbSNP
rs1344710907 1861 dbSNP
rs902414476 1862 dbSNP
rs1043643191 1868 dbSNP
rs1286823225 1868 dbSNP
rs1318315423 1869 dbSNP
rs1304363582 1889 dbSNP
rs1246252508 1890 dbSNP
rs1200876372 1891 dbSNP
rs946631402 1891 dbSNP
rs1292076117 1896 dbSNP
rs911025654 1901 dbSNP
rs578074629 1902 dbSNP
rs933753905 1903 dbSNP
rs1457388878 1907 dbSNP
rs1319541262 1909 dbSNP
rs922380114 1911 dbSNP
rs1139382 1918 dbSNP
rs1442511616 1918 dbSNP
rs1324752980 1919 dbSNP
rs550749527 1920 dbSNP
rs961051479 1923 dbSNP
rs1281581054 1927 dbSNP
rs1062393 1934 dbSNP
rs1292986390 1948 dbSNP
rs1228013134 1951 dbSNP
rs1266518107 1954 dbSNP
rs909568698 1955 dbSNP
rs1347065395 1959 dbSNP
rs1157146831 1967 dbSNP
rs1456920516 1986 dbSNP
rs1450894767 1989 dbSNP
rs1231442362 1998 dbSNP
rs150080587 2007 dbSNP
rs1201392131 2009 dbSNP
rs3203463 2012 dbSNP
rs1157914267 2015 dbSNP
rs970291867 2017 dbSNP
rs557854107 2031 dbSNP
rs1163269566 2038 dbSNP
rs1389410111 2039 dbSNP
rs1385584495 2042 dbSNP
rs539896641 2043 dbSNP
rs1486533150 2046 dbSNP
rs1265710516 2050 dbSNP
rs1409654832 2051 dbSNP
rs1207634505 2057 dbSNP
rs1286872936 2072 dbSNP
rs960141570 2074 dbSNP
rs1264126029 2078 dbSNP
rs1225784748 2082 dbSNP
rs1354404885 2090 dbSNP
rs528197675 2093 dbSNP
rs1207982530 2100 dbSNP
rs1032200295 2106 dbSNP
rs560906332 2111 dbSNP
rs1383285904 2119 dbSNP
rs998960418 2119 dbSNP
rs1425130814 2144 dbSNP
rs542294618 2149 dbSNP
rs904497044 2157 dbSNP
rs768712475 2160 dbSNP
rs1455970526 2169 dbSNP
rs1051885762 2171 dbSNP
rs1043090241 2172 dbSNP
rs1429708361 2179 dbSNP
rs35693484 2179 dbSNP
rs1306487159 2180 dbSNP
rs1434631512 2183 dbSNP
rs933373743 2184 dbSNP
rs1312361722 2186 dbSNP
rs1338741671 2188 dbSNP
rs1229764242 2194 dbSNP
rs1010791537 2198 dbSNP
rs1342731798 2198 dbSNP
rs1204369661 2200 dbSNP
rs889746977 2200 dbSNP
rs1484152354 2203 dbSNP
rs1200647122 2204 dbSNP
rs1178287146 2207 dbSNP
rs1421712552 2211 dbSNP
rs1464320198 2215 dbSNP
rs1189892711 2232 dbSNP
rs1390260346 2240 dbSNP
rs1449331332 2241 dbSNP
rs1376877107 2242 dbSNP
rs1170990487 2243 dbSNP
rs1167324927 2247 dbSNP
rs1343171009 2247 dbSNP
rs1466909760 2248 dbSNP
rs185176477 2249 dbSNP
rs57486163 2249 dbSNP
rs1417316114 2250 dbSNP
rs180868204 2250 dbSNP
rs1295386375 2251 dbSNP
rs773402351 2251 dbSNP
rs1387283651 2252 dbSNP
rs868306484 2252 dbSNP
rs1229849413 2253 dbSNP
rs1268413935 2253 dbSNP
rs1245657544 2254 dbSNP
rs1489052876 2254 dbSNP
rs1187445180 2255 dbSNP
rs1191187695 2255 dbSNP
rs1265707524 2255 dbSNP
rs1473800659 2255 dbSNP
rs1461469770 2256 dbSNP
rs1160156708 2257 dbSNP
rs1350554698 2257 dbSNP
rs1455873057 2257 dbSNP
rs1437090908 2259 dbSNP
rs1292936186 2260 dbSNP
rs1343376709 2261 dbSNP
rs898996661 2261 dbSNP
rs1244560591 2263 dbSNP
rs1198396188 2265 dbSNP
rs1210964159 2265 dbSNP
rs1349448855 2265 dbSNP
rs1221717056 2266 dbSNP
rs1343248344 2267 dbSNP
rs1321871187 2268 dbSNP
rs1255779478 2269 dbSNP
rs1264254732 2269 dbSNP
rs1484337347 2270 dbSNP
rs1183299219 2271 dbSNP
rs1414622048 2271 dbSNP
rs1471700446 2271 dbSNP
rs200761366 2272 dbSNP
rs1163959785 2273 dbSNP
rs1345011576 2273 dbSNP
rs1295470018 2274 dbSNP
rs1369730079 2274 dbSNP
rs1227818443 2275 dbSNP
rs1439570080 2275 dbSNP
rs111245032 2276 dbSNP
rs1379239073 2276 dbSNP
rs1383659068 2277 dbSNP
rs1037537573 2278 dbSNP
rs1206520513 2279 dbSNP
rs1394523358 2279 dbSNP
rs1482316684 2279 dbSNP
rs1212470238 2281 dbSNP
rs1238318416 2282 dbSNP
rs1401150050 2282 dbSNP
rs1472604455 2282 dbSNP
rs1298598699 2283 dbSNP
rs1169203569 2284 dbSNP
rs1392102772 2284 dbSNP
rs1463447292 2284 dbSNP
rs1221244964 2285 dbSNP
rs1229783511 2285 dbSNP
rs1279819014 2285 dbSNP
rs1297562841 2285 dbSNP
rs1334051611 2285 dbSNP
rs1335964079 2285 dbSNP
rs1337827039 2285 dbSNP
rs1359343929 2285 dbSNP
rs1366813510 2285 dbSNP
rs1369686454 2285 dbSNP
rs144054574 2285 dbSNP
rs1441989346 2285 dbSNP
rs1446842751 2285 dbSNP
rs71572094 2285 dbSNP
rs868158998 2285 dbSNP
rs1157685148 2286 dbSNP
rs1196806848 2286 dbSNP
rs1413649513 2286 dbSNP
rs1420820838 2286 dbSNP
rs1480011808 2286 dbSNP
rs1228030652 2287 dbSNP
rs1290636899 2287 dbSNP
rs1324856226 2287 dbSNP
rs1330851781 2287 dbSNP
rs1351272464 2287 dbSNP
rs1358648189 2287 dbSNP
rs1382153522 2287 dbSNP
rs1403442797 2287 dbSNP
rs1407558400 2287 dbSNP
rs1211535074 2290 dbSNP
rs1388299476 2290 dbSNP
rs1167378305 2291 dbSNP
rs1444666650 2294 dbSNP
rs1386575958 2295 dbSNP
rs1490171889 2298 dbSNP
rs1196968446 2303 dbSNP
rs1253710948 2311 dbSNP
rs1472679324 2314 dbSNP
rs940408365 2317 dbSNP
rs1184880875 2318 dbSNP
rs907639914 2321 dbSNP
rs1163360569 2323 dbSNP
rs556622699 2328 dbSNP
rs1056773352 2331 dbSNP
rs1423302588 2331 dbSNP
rs1255890320 2332 dbSNP
rs1371623947 2333 dbSNP
rs111246005 2334 dbSNP
rs1305183694 2334 dbSNP
rs1409434858 2334 dbSNP
rs1245549684 2335 dbSNP
rs762519118 2335 dbSNP
rs201910247 2336 dbSNP
rs71276924 2336 dbSNP
rs1220178549 2337 dbSNP
rs1276492709 2337 dbSNP
rs1483296634 2337 dbSNP
rs1194841913 2338 dbSNP
rs1248035316 2338 dbSNP
rs113779671 2339 dbSNP
rs1187561639 2340 dbSNP
rs1443821081 2340 dbSNP
rs1484305666 2340 dbSNP
rs1273061707 2341 dbSNP
rs1443312760 2343 dbSNP
rs192123254 2346 dbSNP
rs1049574253 2347 dbSNP
rs1391140123 2347 dbSNP
rs1360180643 2348 dbSNP
rs1404566050 2349 dbSNP
rs1491200112 2349 dbSNP
rs557779840 2349 dbSNP
rs927000977 2349 dbSNP
rs1491358657 2350 dbSNP
rs1286033836 2351 dbSNP
rs1483997902 2351 dbSNP
rs1200739432 2354 dbSNP
rs537908669 2355 dbSNP
rs1242875103 2357 dbSNP
rs1459621939 2363 dbSNP
rs1340154125 2364 dbSNP
rs1249139611 2369 dbSNP
rs1428471800 2370 dbSNP
rs1168695181 2371 dbSNP
rs1307407982 2373 dbSNP
rs552149617 2374 dbSNP
rs1368500141 2375 dbSNP
rs1437427682 2380 dbSNP
rs933848166 2386 dbSNP
rs1365758663 2393 dbSNP
rs1293166413 2395 dbSNP
rs1313807202 2396 dbSNP
rs1307278521 2401 dbSNP
rs1233480927 2403 dbSNP
rs1262174040 2404 dbSNP
rs922359254 2405 dbSNP
rs1425232148 2407 dbSNP
rs1210011972 2412 dbSNP
rs1268212730 2418 dbSNP
rs187379292 2419 dbSNP
rs6983989 2425 dbSNP
rs1269903506 2430 dbSNP
rs1434154853 2431 dbSNP
rs1472248060 2435 dbSNP
rs1364059504 2436 dbSNP
rs866112077 2440 dbSNP
rs1473748123 2447 dbSNP
rs1250080088 2452 dbSNP
rs921989616 2454 dbSNP
rs150947186 2458 dbSNP
rs909517865 2459 dbSNP
rs974923423 2463 dbSNP
rs1343179212 2467 dbSNP
rs1208182380 2468 dbSNP
rs1355866793 2472 dbSNP
rs534251542 2474 dbSNP
rs1268192317 2478 dbSNP
rs1230480956 2479 dbSNP
rs879398854 2481 dbSNP
rs566885165 2482 dbSNP
rs1287567354 2486 dbSNP
rs1213852192 2492 dbSNP
rs374117220 2492 dbSNP
rs548897668 2492 dbSNP
rs992997116 2494 dbSNP
rs1183253739 2499 dbSNP
rs960462507 2503 dbSNP
rs1157694773 2505 dbSNP
rs1167030993 2509 dbSNP
rs956424975 2512 dbSNP
rs998908117 2514 dbSNP
rs1332810642 2518 dbSNP
rs1302238457 2519 dbSNP
rs1031063865 2521 dbSNP
rs1411273151 2522 dbSNP
rs968795071 2523 dbSNP
rs981719396 2523 dbSNP
rs1221523583 2524 dbSNP
rs970463894 2525 dbSNP
rs1314285192 2531 dbSNP
rs142558461 2532 dbSNP
rs372155631 2536 dbSNP
rs1385082302 2540 dbSNP
rs1012036676 2541 dbSNP
rs1159879468 2548 dbSNP
rs898992228 2550 dbSNP
rs1484266475 2553 dbSNP
rs536298299 2558 dbSNP
rs1455319308 2560 dbSNP
rs1016217333 2561 dbSNP
rs1445153849 2567 dbSNP
rs1005194529 2568 dbSNP
rs775476615 2575 dbSNP
rs1051787289 2576 dbSNP
rs933281951 2591 dbSNP
rs569125670 2596 dbSNP
rs1329316632 2599 dbSNP
rs900597561 2603 dbSNP
rs889697532 2608 dbSNP
rs1197408743 2610 dbSNP
rs1439574304 2614 dbSNP
rs1304068254 2617 dbSNP
rs1382970939 2617 dbSNP
rs1245844095 2618 dbSNP
rs1039099889 2622 dbSNP
rs113890535 2623 dbSNP
rs41408945 2624 dbSNP
rs758157804 2625 dbSNP
rs1036832410 2626 dbSNP
rs145594484 2629 dbSNP
rs888233775 2631 dbSNP
rs928874473 2633 dbSNP
rs1182889511 2636 dbSNP
rs1241145121 2637 dbSNP
rs140157061 2640 dbSNP
rs528159830 2643 dbSNP
rs560849969 2644 dbSNP
rs1023379146 2647 dbSNP
rs1407854714 2649 dbSNP
rs1177843582 2651 dbSNP
rs990522802 2652 dbSNP
rs1451221092 2658 dbSNP
rs1326434151 2669 dbSNP
rs1367891701 2673 dbSNP
rs993461323 2682 dbSNP
rs542596881 2683 dbSNP
rs1360395440 2688 dbSNP
rs530383322 2690 dbSNP
rs1432428601 2692 dbSNP
rs924736449 2694 dbSNP
rs1016492723 2705 dbSNP
rs1448601949 2722 dbSNP
rs968782053 2726 dbSNP
rs1193898240 2730 dbSNP
rs1241273959 2731 dbSNP
rs1474332628 2731 dbSNP
rs1021747200 2737 dbSNP
rs760196602 2741 dbSNP
rs1158844137 2743 dbSNP
rs1415359127 2745 dbSNP
rs986112336 2749 dbSNP
rs1427719858 2755 dbSNP
rs953481215 2756 dbSNP
rs1171272701 2757 dbSNP
rs1325021020 2764 dbSNP
rs1030343619 2770 dbSNP
rs886371283 2772 dbSNP
rs901091855 2773 dbSNP
rs1478027976 2777 dbSNP
rs1290290812 2780 dbSNP
rs181853150 2781 dbSNP
rs997522027 2782 dbSNP
rs113334945 2785 dbSNP
rs1225417022 2786 dbSNP
rs1190658882 2787 dbSNP
rs1269354596 2788 dbSNP
rs1479900277 2790 dbSNP
rs1196920557 2800 dbSNP
rs1413487674 2802 dbSNP
rs988981615 2805 dbSNP
rs544890402 2809 dbSNP
rs144849948 2812 dbSNP
rs1407579257 2814 dbSNP
rs1365405877 2815 dbSNP
rs779745759 2815 dbSNP
rs1048154373 2816 dbSNP
rs1310143142 2819 dbSNP
rs948512695 2820 dbSNP
rs1204574630 2821 dbSNP
rs894101723 2829 dbSNP
rs879591622 2834 dbSNP
rs1348387794 2837 dbSNP
rs539625117 2838 dbSNP
rs190092135 2839 dbSNP
rs185398227 2842 dbSNP
rs938932372 2842 dbSNP
rs41494944 2844 dbSNP
rs1299150278 2846 dbSNP
rs947560974 2849 dbSNP
rs1363863644 2850 dbSNP
rs1180378813 2861 dbSNP
rs1361573084 2863 dbSNP
rs914763705 2866 dbSNP
rs928892223 2870 dbSNP
rs1045958792 2876 dbSNP
rs1449790727 2877 dbSNP
rs181064620 2891 dbSNP
rs1170910829 2892 dbSNP
rs1030707821 2895 dbSNP
rs976148759 2900 dbSNP
rs1454480326 2901 dbSNP
rs1315700436 2909 dbSNP
rs1414384816 2915 dbSNP
rs1243442276 2916 dbSNP
rs1252859226 2926 dbSNP
rs916236416 2927 dbSNP
rs41361446 2935 dbSNP
rs1015491878 2937 dbSNP
rs1462306638 2937 dbSNP
rs1389648041 2938 dbSNP
rs149758683 2943 dbSNP
rs1184367683 2949 dbSNP
rs908935726 2950 dbSNP
rs1374055892 2951 dbSNP
rs952522708 2953 dbSNP
rs983699764 2955 dbSNP
rs1209222694 2956 dbSNP
rs950544101 2961 dbSNP
rs1324617612 2964 dbSNP
rs1026784794 2965 dbSNP
rs1276636320 2974 dbSNP
rs1030295098 2980 dbSNP
rs749919482 2983 dbSNP
rs866820752 2984 dbSNP
rs41368551 2986 dbSNP
rs964727691 2990 dbSNP
rs1017634316 2993 dbSNP
rs1011546298 2994 dbSNP
rs115681473 2995 dbSNP
rs1282759818 2996 dbSNP
rs372830311 2996 dbSNP
rs1053169632 3002 dbSNP
rs1447710047 3012 dbSNP
rs999468179 3015 dbSNP
rs562639481 3017 dbSNP
rs1428388658 3020 dbSNP
rs1262834315 3023 dbSNP
rs1370022518 3025 dbSNP
rs1165643603 3026 dbSNP
rs1425758707 3033 dbSNP
rs1191512065 3034 dbSNP
rs546369861 3041 dbSNP
rs1480887145 3042 dbSNP
rs947631979 3049 dbSNP
rs1404072535 3050 dbSNP
rs1472766017 3053 dbSNP
rs1323297471 3054 dbSNP
rs914709541 3057 dbSNP
rs141472595 3059 dbSNP
rs948955255 3059 dbSNP
rs1381404630 3064 dbSNP
rs1293182669 3065 dbSNP
rs528313658 3066 dbSNP
rs188621799 3079 dbSNP
rs548753329 3080 dbSNP
rs369205124 3082 dbSNP
rs962091133 3087 dbSNP
rs1223187762 3088 dbSNP
rs773277626 3090 dbSNP
rs1261774515 3094 dbSNP
rs61299886 3103 dbSNP
rs1271509234 3105 dbSNP
rs1288642819 3106 dbSNP
rs750391462 3125 dbSNP
rs1480878459 3129 dbSNP
rs983220926 3130 dbSNP
rs1199053628 3132 dbSNP
rs563102608 3139 dbSNP
rs1224007287 3142 dbSNP
rs950566626 3146 dbSNP
rs923080152 3147 dbSNP
rs1296106845 3149 dbSNP
rs1364243256 3149 dbSNP
rs753074916 3149 dbSNP
rs1290668962 3150 dbSNP
rs551430656 3154 dbSNP
rs549005675 3157 dbSNP
rs1017498128 3158 dbSNP
rs183473113 3160 dbSNP
rs765228938 3163 dbSNP
rs1316782212 3165 dbSNP
rs1032206764 3168 dbSNP
rs781294366 3170 dbSNP
rs1164271714 3173 dbSNP
rs998937219 3175 dbSNP
rs35893445 3178 dbSNP
rs76828517 3178 dbSNP
rs71512466 3179 dbSNP
rs75555989 3179 dbSNP
rs1156747989 3181 dbSNP
rs35075569 3181 dbSNP
rs1013010193 3184 dbSNP
rs1481745805 3186 dbSNP
rs894740658 3191 dbSNP
rs1472208240 3197 dbSNP
rs1267929538 3198 dbSNP
rs34061524 3199 dbSNP
rs1487186368 3200 dbSNP
rs1407571195 3202 dbSNP
rs142848129 3203 dbSNP
rs1216063630 3204 dbSNP
rs561535748 3207 dbSNP
rs780342041 3208 dbSNP
rs758752797 3210 dbSNP
rs1047957048 3213 dbSNP
rs1443934805 3220 dbSNP
rs932195984 3222 dbSNP
rs542728211 3225 dbSNP
rs1328940856 3226 dbSNP
rs202068735 3230 dbSNP
rs929056873 3233 dbSNP
rs1389049195 3235 dbSNP
rs1309470232 3236 dbSNP
rs1040434683 3237 dbSNP
rs922985520 3238 dbSNP
rs975920076 3240 dbSNP
rs1185526840 3241 dbSNP
rs943143093 3243 dbSNP
rs575711434 3245 dbSNP
rs556923709 3247 dbSNP
rs952625282 3248 dbSNP
rs1170758600 3251 dbSNP
rs957628980 3252 dbSNP
rs1031653641 3253 dbSNP
rs1338139829 3255 dbSNP
rs977369061 3260 dbSNP
rs1456468055 3261 dbSNP
rs78835109 3262 dbSNP
rs34238026 3263 dbSNP
rs749219061 3263 dbSNP
rs1491049057 3264 dbSNP
rs1215363934 3269 dbSNP
rs1272503746 3270 dbSNP
rs971468687 3270 dbSNP
rs1035948187 3271 dbSNP
rs201964838 3271 dbSNP
rs991714061 3271 dbSNP
rs1024310413 3275 dbSNP
rs1235489570 3277 dbSNP
rs1013043217 3280 dbSNP
rs190605760 3281 dbSNP
rs981181601 3294 dbSNP
rs1465947992 3296 dbSNP
rs1476643838 3300 dbSNP
rs1177953788 3305 dbSNP
rs967120965 3306 dbSNP
rs1469713080 3307 dbSNP
rs1019957028 3313 dbSNP
rs1245771866 3321 dbSNP
rs759568551 3322 dbSNP
rs1207738124 3323 dbSNP
rs1485712946 3324 dbSNP
rs1005791028 3325 dbSNP
rs1011279080 3330 dbSNP
rs1283993202 3330 dbSNP
rs893377745 3333 dbSNP
rs1199782815 3336 dbSNP
rs1311008570 3343 dbSNP
rs1029269580 3348 dbSNP
rs1448692644 3354 dbSNP
rs138347576 3357 dbSNP
rs578133569 3358 dbSNP
rs996849324 3359 dbSNP
rs1300641694 3361 dbSNP
rs1229182876 3362 dbSNP
rs901980106 3375 dbSNP
rs1429358116 3389 dbSNP
rs774858147 3390 dbSNP
rs1170335215 3394 dbSNP
rs928921075 3402 dbSNP
rs1434658301 3404 dbSNP
rs1318054229 3406 dbSNP
rs113418427 3408 dbSNP
rs1304434607 3409 dbSNP
rs1304030891 3410 dbSNP
rs1251324411 3416 dbSNP
rs1231109470 3417 dbSNP
rs72667359 3419 dbSNP
rs112802896 3420 dbSNP
rs1491377449 3420 dbSNP
rs112010967 3421 dbSNP
rs886559994 3421 dbSNP
rs1351300966 3425 dbSNP
rs549174192 3425 dbSNP
rs930671143 3425 dbSNP
rs1269108675 3429 dbSNP
rs776894338 3429 dbSNP
rs991394854 3429 dbSNP
rs1450734916 3430 dbSNP
rs1387796383 3431 dbSNP
rs564560971 3431 dbSNP
rs187635878 3436 dbSNP
rs935951612 3439 dbSNP
rs1378829406 3441 dbSNP
rs183088875 3444 dbSNP
rs191683446 3446 dbSNP
rs114713114 3457 dbSNP
rs1365118759 3459 dbSNP
rs112910272 3460 dbSNP
rs1330974075 3467 dbSNP
rs1336473625 3470 dbSNP
rs372190124 3471 dbSNP
rs967109633 3472 dbSNP
rs981310457 3472 dbSNP
rs547269374 3473 dbSNP
rs1024385339 3484 dbSNP
rs1280184317 3491 dbSNP
rs989797100 3493 dbSNP
rs1355188331 3495 dbSNP
rs1207764750 3498 dbSNP
rs1274456269 3505 dbSNP
rs1437954294 3510 dbSNP
rs1344330605 3511 dbSNP
rs1236842504 3514 dbSNP
rs991528442 3515 dbSNP
rs1446979261 3519 dbSNP
rs759180521 3530 dbSNP
rs1368321397 3543 dbSNP
rs112806978 3546 dbSNP
rs141763252 3554 dbSNP
rs543242260 3566 dbSNP
rs575629217 3568 dbSNP
rs1282249918 3575 dbSNP
rs1314567302 3582 dbSNP
rs1409413585 3593 dbSNP
rs1329406027 3595 dbSNP
rs951668907 3599 dbSNP
rs563489079 3601 dbSNP
rs996408318 3604 dbSNP
rs1315460633 3605 dbSNP
rs1339695813 3606 dbSNP
rs3077263 3608 dbSNP
rs5893538 3608 dbSNP
rs1431555974 3610 dbSNP
rs1025860784 3611 dbSNP
rs1167476606 3612 dbSNP
rs187202979 3613 dbSNP
rs901500208 3621 dbSNP
rs1463045816 3623 dbSNP
rs3735704 3625 dbSNP
rs1255880546 3630 dbSNP
rs1422386343 3630 dbSNP
rs1007297769 3632 dbSNP
rs1422373493 3640 dbSNP
rs1477627733 3643 dbSNP
rs1168611638 3645 dbSNP
rs1408469084 3646 dbSNP
rs1470895631 3647 dbSNP
rs1303405002 3653 dbSNP
rs1257270126 3654 dbSNP
rs1394024866 3658 dbSNP
rs374918131 3658 dbSNP
rs1320048938 3664 dbSNP
rs888839430 3676 dbSNP
rs1217711301 3677 dbSNP
rs1272549336 3681 dbSNP
rs1195338069 3686 dbSNP
rs1275723794 3686 dbSNP
rs1005037678 3689 dbSNP
rs552967978 3690 dbSNP
rs886507477 3692 dbSNP
rs1049113348 3693 dbSNP
rs930744444 3697 dbSNP
rs895115731 3699 dbSNP
rs1262946882 3702 dbSNP
rs1242896123 3703 dbSNP
rs534577766 3704 dbSNP
rs1054309162 3711 dbSNP
rs1354512533 3713 dbSNP
rs1480775398 3713 dbSNP
rs1175489443 3715 dbSNP
rs1288821919 3716 dbSNP
rs1376931827 3719 dbSNP
rs555494473 3726 dbSNP
rs746652424 3727 dbSNP
rs1360974949 3730 dbSNP
rs1398985698 3733 dbSNP
rs1295910752 3755 dbSNP
rs937270489 3771 dbSNP
rs1307377182 3793 dbSNP
rs1404961077 3793 dbSNP
rs1241898080 3795 dbSNP
rs3077262 3795 dbSNP
rs3832540 3795 dbSNP
rs770953756 3795 dbSNP
rs981256680 3795 dbSNP
rs1261644216 3803 dbSNP
rs1353496082 3806 dbSNP
rs1386799436 3810 dbSNP
rs1392278054 3813 dbSNP
rs1161028560 3814 dbSNP
rs1190627248 3815 dbSNP
rs945884128 3816 dbSNP
rs924555822 3819 dbSNP
rs1380868519 3820 dbSNP
rs1418823827 3821 dbSNP
rs1156621155 3832 dbSNP
rs1366993688 3842 dbSNP
rs989869214 3843 dbSNP
rs1292434369 3866 dbSNP
rs1364923532 3867 dbSNP
rs573911830 3874 dbSNP
rs1310564784 3879 dbSNP
rs1473838819 3881 dbSNP
rs1376849923 3884 dbSNP
rs779688670 3886 dbSNP
rs1181743678 3888 dbSNP
rs555248103 3907 dbSNP
rs1360420236 3918 dbSNP
rs867322034 3932 dbSNP
rs991559564 3934 dbSNP
rs1481631096 3939 dbSNP
rs966307526 3941 dbSNP
rs537297797 3945 dbSNP
rs1238645379 3960 dbSNP
rs1208282281 3965 dbSNP
rs1176535039 3972 dbSNP
rs1386937428 3973 dbSNP
rs1405565518 3976 dbSNP
rs113535044 3983 dbSNP
rs909921173 3990 dbSNP
rs551455513 3992 dbSNP
rs1463033414 3996 dbSNP
rs1229959575 4000 dbSNP
rs1317605820 4007 dbSNP
rs1400133497 4007 dbSNP
rs757879431 4007 dbSNP
rs1228132322 4008 dbSNP
rs1310798851 4012 dbSNP
rs950859871 4015 dbSNP
rs1027788824 4016 dbSNP
rs1257573564 4028 dbSNP
rs749906654 4029 dbSNP
rs572703551 4032 dbSNP
rs1244719345 4041 dbSNP
rs1472973709 4044 dbSNP
rs895259212 4057 dbSNP
rs1025934459 4059 dbSNP
rs1278824420 4060 dbSNP
rs1055123210 4068 dbSNP
rs998425396 4074 dbSNP
rs1170760564 4075 dbSNP
rs1437114716 4076 dbSNP
rs1422377392 4082 dbSNP
rs1003980113 4088 dbSNP
rs539542394 4094 dbSNP
rs1018640989 4095 dbSNP
rs1447670292 4102 dbSNP
rs565652914 4110 dbSNP
rs945958919 4115 dbSNP
rs1301473373 4121 dbSNP
rs1364329977 4134 dbSNP
rs778544019 4139 dbSNP
rs888879835 4141 dbSNP
rs1054575827 4142 dbSNP
rs1316191124 4151 dbSNP
rs1225458642 4157 dbSNP
rs547385847 4160 dbSNP
rs528767794 4162 dbSNP
rs1442941407 4166 dbSNP
rs1209095149 4170 dbSNP
rs1459107888 4171 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177618. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_3_8 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000395957.2 | 3UTR | AUCCCCUCUCUUCCUCCCCACCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
43 hsa-miR-2681-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT095679 RBM27 RNA binding motif protein 27 2 4
MIRT217751 TBPL1 TATA-box binding protein like 1 2 2
MIRT344142 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT353812 PCBP1 poly(rC) binding protein 1 2 2
MIRT457093 IGF2R insulin like growth factor 2 receptor 2 2
MIRT463686 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT466768 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 8
MIRT481861 AP1G1 adaptor related protein complex 1 gamma 1 subunit 2 8
MIRT496692 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT515384 RPL7 ribosomal protein L7 2 2
MIRT519785 ZNF354B zinc finger protein 354B 2 10
MIRT530117 SLC25A42 solute carrier family 25 member 42 2 2
MIRT530428 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT545655 SPARC secreted protein acidic and cysteine rich 2 2
MIRT545698 NUTF2 nuclear transport factor 2 2 2
MIRT550287 APOL6 apolipoprotein L6 2 2
MIRT556356 MAFK MAF bZIP transcription factor K 2 2
MIRT563763 ZNF678 zinc finger protein 678 2 2
MIRT566660 NAMPT nicotinamide phosphoribosyltransferase 2 2
MIRT571896 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT575540 Map4 microtubule-associated protein 4 2 2
MIRT610626 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT635327 BMS1 BMS1, ribosome biogenesis factor 2 2
MIRT637795 OLA1 Obg like ATPase 1 2 4
MIRT638243 SLC1A5 solute carrier family 1 member 5 2 2
MIRT642976 TESPA1 thymocyte expressed, positive selection associated 1 2 2
MIRT646609 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT658895 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT686070 KCNA7 potassium voltage-gated channel subfamily A member 7 2 2
MIRT693410 NUDT16 nudix hydrolase 16 2 2
MIRT699020 SOAT1 sterol O-acyltransferase 1 2 2
MIRT702180 LYRM4 LYR motif containing 4 2 2
MIRT704727 CEP135 centrosomal protein 135 2 2
MIRT709001 ZNF28 zinc finger protein 28 2 2
MIRT709445 TGFBRAP1 transforming growth factor beta receptor associated protein 1 2 2
MIRT709456 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT711983 DCTN6 dynactin subunit 6 2 2
MIRT713090 ZG16 zymogen granule protein 16 2 2
MIRT714871 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT717025 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT721910 BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2 2
MIRT722085 SMC2 structural maintenance of chromosomes 2 2 2
MIRT725027 CX3CL1 C-X3-C motif chemokine ligand 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-2681-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-2681-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-2681-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-2681-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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