miRTarBase - #MIRT464945


—
pre-miRNA Information
pre-miRNA hsa-mir-4697   
Genomic Coordinates chr11: 133898504 - 133898581
Description Homo sapiens miR-4697 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4697-5p
Sequence 10| AGGGGGCGCAGUCACUGACGUG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs549326907 2 dbSNP
rs897782230 7 dbSNP
rs748950280 8 dbSNP
rs978998780 15 dbSNP
rs968922289 19 dbSNP
rs3802919 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TXLNA   
Synonyms IL14, TXLN
Description taxilin alpha
Transcript NM_175852   
Expression
Putative miRNA Targets on TXLNA
3'UTR of TXLNA
(miRNA target sites are highlighted)		 
>TXLNA|NM_175852|3'UTR
   1 AGAGCCTGGTGTTGGGTCATGCTGGGAAGGGAGCGGCAGCCCAGCCAGGCCTGGCCCATAAAAGGCTCCCATGCTGAGCA
  81 GCCCATTGCTGAAGCCAGGATGTTCTGACCTGGCTGGCATCTGGCACTTGCAATTTTGGATTTTGTGGGTCAGTTTTACG
 161 TACATAGGGCATTTTGCAAGGCCTTGCAAATGCATTTATACCTGTAAGTGTACAGTGGGCTTGCATTGGGGATGGGGGTG
 241 TGTACAGATGAAGTCAGTGGCTTGTCTGTGAGCTGAAGAGTCTTGAGAGGGGCTGTCATCTGTAGCTGCCATCACAGTGA
 321 GTTGGCAGAAGTGACTTGAGCATTTCTCTGTCTGATTTGAGGCTCAGACCCCTCCCTGCCCTTCAGAGCTCAAGACAAGT
 401 AATACACCCAGGTCTTGACTGCATTTGTCTTGTGAGCAGGGCTTGCTTGGTCAGCTCAGGCCCTCCTAGCTGCTCTGGAG
 481 GCTCCTTTGATTCTCTAGACCTGGAAAAGGTGTCCCTAGGCAGAGCCCTGGCAGGGCGCTCAGAGCTGGGGATTTCCTGC
 561 CTGGAACAAGGGACCTGGAGAATGTTTTTGCGTGGGATGATGTGCTGGTCAGGAGCCCCTTGGGCATCGCTTCCCCTGCC
 641 CTTTGGTAGTGCCAGGACCAGGCCAATGATGCTTCTCAGTAGCCTTATCATTCACAGGTGCCTCTCTAGCCTGCACAAAT
 721 GATTGACAAGAGATCACCCAAAGGATTATTTCTGAAGGTGTTTTTTTCTTTATTTCTTTTTCTTTTTTTTTTTTTTTCTT
 801 TTTCTTTTTTTTTTGCACATGACAGTGTTTGTATTGAGGACCTTCCAAGGAAGAGGGATGCTGTAGCAGTGGTGCCTGGG
 881 TGCCTGGCCTCCAGTGTCCCACCTCCTTCACCACCCCACTTGGCTCCTTTGCCATCTTGATGCTGAGGTTTCCTGTTTGG
 961 TGAGATCAGGTTGTTTGTGGTAAAAGAAAGGAAAGGGCTTCTGATGGCTTTGCCACAAGCTTACCTGTGGGTTTCAGTCC
1041 TGAGAGGCCACCACCAGTTCCCATCAGCACTGTCTCCATGCAGCAGTTGCTGGGTCCCATGTCCAGCTGCCTCTTTGGCT
1121 TCATGGGTTTTTCTGCTTCCTGCCCCCACCCCCACATGTGCAATCCTCAAGATTTGTCCTGATTCTATTTCCTGGCACCT
1201 CCCTGCCTGTCCTTGGGGATTCTACTTCTTCCTGTGTGGGAGCCCATAGCTGTTGTCTAACAGGTAAGAAATGAAATTGA
1281 ACTATTGACTGGGCCCCAGAAATCCATAAAATGGCTGCAGACAGTTGTTTCTGTGTCCTGTTCTACCCCCACTCCAGTAC
1361 ATAACTACTATGTACTGTGTAGAGCCATTCTATATGCTGAATGTTCTGCTGTTGCAAACTTGCCAGGGTATTAGCCAGTG
1441 TTTGTGCCAAGCAGTTTTCTGGGACAACAGAATGACTCAGACCAAGATGGATAGGATGGTTAGGGCTTTGCTTCTTGCTG
1521 TTTTTCTTTGAAGCTAGTTCATTGTCCTGCAGGTCCCTTCATCTTCCATACCTAGCCCACTCTTTTAGCCCTTACCTTAA
1601 ATCTCTCAGATAAGTTGGTTCACAAAGAATGTTAAGTACTGAATCATGTGTGACTGAGACCAGAGATGGCAAATGAATGG
1681 CACACCATTTCTCCTTCTCCTGCCCCAGGGCAGGTACCACTGATCTGCATCAGAGTTGCCTGCTATTCTCTGGTGTATCC
1761 TTCACATCTAGGTGCCCTCAAGCAGCTGTGTGAGTGTTGAGATCTCTGCCATCTCTGGCTGAGATACTGCTGTCCTGTGA
1841 AGTGTTTCCCATGACCTTTTTCTTCCCCTTTGAATCCCTCTGTCTGGAGTAGTCCTTGCCTCTTCCTGCTCCAGTAGGGC
1921 CTTTTCCCTACCCCAGCCCCTGTGCCAGGCTAAGCTGGTACAAGAGCTGCCAACCTCACAGAGTGTTTGCTAGGCGAGAG
2001 AGGTGCAGGGAAGAGGCAGAGGTATGCACCTTCCCCCTTGAAGAGAGGGGAAAGGCCTACAGTGGCCCACATAATTGCCT
2081 GACTCACACTTCAGCTACCTCTTAATGCCTGTGGAGGGACTGGAGCTGCTGGATCCCAGTGTGGTGGTGTAGGAGGCCAC
2161 AGTGAGCAGGTGGCCCCAGCTGGGTTTCCCAGGTCAGGAATGTGGGCCCCAGGCAAGGTGCAGCCTTTGCTCACAGCTCC
2241 ATCCATGTCTAGACCTTCAGGCCAGTCTGCAGATGAGGTTCCCTACCTTTTTCTTCTCTTCATTGACCAAATCAACCAAT
2321 CACTACAGCTGCTCTGCTTCTGCTTTCCAAAGTAGCCCAGGTCCTGGGCCAGATGCAGGGGAGGTGCCTATCCATGAGTG
2401 AAGGCCAGTGTCTTCCTCACCTGGGTGGGTCCCACACTTGTGACCTCAGTTTTAGGACCAAGATCTGTGTTGGTTTCTTA
2481 GATTGCTAGCTTTTCCTCCAGGGGACCACAGCAGGTGAAGCTCAAGAGCGCATGGCTCTGCTAATAGTAAATTGTTTTCA
2561 GGGCCTTGTCCAGCTGAGAGCTTCATGTCCACCAGATTCTGAGAGGTGTCAGCAGCACTTTTTTTTTTTATTTGTTGTTT
2641 GTTTTCCATGAGGTTATCGGACCATGGGCTGAGCTCAGGCACTTTCTGTAGGAGACTGTTATTTCTGTAAAGATGGTTAT
2721 TTAACCCTCCTCCACCCCATCACGGTGGCCCTGAGGGCTGACCCGGAGGCCAGTGGAGCTGCCTGGTGTCCACGGGGGAG
2801 GGCCAAGGCCTGCTGAGCTGATTCTCCAGCTGCTGCCCCAGCCTTTCCGCCTTGCACAGCACAGAGGTGGTCACCCCAGG
2881 GACAGCCAGGCACCTGCTCCTCTTGCCCTTCCTGGGGGAAGGGAGCTGCCTTCTGTCCCTGTAACTGCTTTCCTTATGGC
2961 CCAGCCCGGCCACTCAGACTTGTTTGAAGCTGCACTGGCAGCTTTTTTGTCTCCTTTGGGTATTCACAACAGCCAGGGAC
3041 TTGATTTTGATGTATTTTAAACCACATTAAATAAAGAGTCTGTTGCCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
3121 AAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gugcagucACUGA-CGCGGGGGa 5'
                  || :|  :|||||| 
Target 5' ggtttttcTGCTTCCTGCCCCCa 3'
 1126 - 1148 126.00 -14.90
2 
miRNA  3' gugcaGUCACUGACGCGGGGga 5'
               :| |||||| |||||  
Target 5' tgaacTATTGACTGGGCCCCag 3'
 1278 - 1299 121.00 -20.70
3 
miRNA  3' gugCAGUCACUG-ACGCGGGGga 5'
             |||||  |: || |||||  
Target 5' cagGTCAGGAATGTGGGCCCCag 3'
 2190 - 2212 115.00 -22.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30533795 36 COSMIC
COSN30150144 77 COSMIC
COSN1103020 84 COSMIC
COSN31960211 115 COSMIC
COSN22151784 203 COSMIC
COSN8457000 320 COSMIC
COSN5740662 629 COSMIC
COSN32008108 687 COSMIC
COSN16232289 799 COSMIC
COSN24048544 837 COSMIC
COSN15737231 1064 COSMIC
COSN1443421 1104 COSMIC
COSN15898551 1332 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs778298506 3 dbSNP
rs368222281 7 dbSNP
rs1358000585 9 dbSNP
rs1346928012 10 dbSNP
rs1208246219 12 dbSNP
rs1282104471 13 dbSNP
rs1398847632 15 dbSNP
rs371805652 16 dbSNP
rs779328322 17 dbSNP
rs376120838 18 dbSNP
rs559390941 20 dbSNP
rs1022107796 21 dbSNP
rs1235572338 23 dbSNP
rs1283080994 25 dbSNP
rs968314533 30 dbSNP
rs779679168 35 dbSNP
rs367823275 36 dbSNP
rs1175793744 39 dbSNP
rs1362374894 40 dbSNP
rs1242956639 44 dbSNP
rs768390096 50 dbSNP
rs1172001586 63 dbSNP
rs1377506047 80 dbSNP
rs1466562511 86 dbSNP
rs923889153 89 dbSNP
rs955326348 90 dbSNP
rs1297701341 96 dbSNP
rs570844333 102 dbSNP
rs574306396 111 dbSNP
rs1309943047 115 dbSNP
rs942426715 116 dbSNP
rs1038115318 122 dbSNP
rs1231819746 128 dbSNP
rs779305238 128 dbSNP
rs1305104230 131 dbSNP
rs541820814 132 dbSNP
rs1054843151 134 dbSNP
rs894897188 149 dbSNP
rs1201059722 151 dbSNP
rs920747316 160 dbSNP
rs1010547664 161 dbSNP
rs930848163 166 dbSNP
rs1397064700 185 dbSNP
rs1434011222 201 dbSNP
rs1170055660 203 dbSNP
rs1371380208 205 dbSNP
rs1229564635 213 dbSNP
rs1047965372 215 dbSNP
rs1331879846 216 dbSNP
rs563203774 227 dbSNP
rs1438384742 237 dbSNP
rs1021988422 239 dbSNP
rs1282017959 245 dbSNP
rs966931774 248 dbSNP
rs1484518452 258 dbSNP
rs16834918 259 dbSNP
rs1259200693 261 dbSNP
rs16834922 264 dbSNP
rs995167499 265 dbSNP
rs1212165986 270 dbSNP
rs955605062 273 dbSNP
rs986031718 283 dbSNP
rs1259991096 285 dbSNP
rs1430326148 286 dbSNP
rs1171508260 293 dbSNP
rs1465131106 299 dbSNP
rs778621264 302 dbSNP
rs563974010 304 dbSNP
rs1167078037 312 dbSNP
rs974028495 314 dbSNP
rs759871288 316 dbSNP
rs918618363 335 dbSNP
rs1286690359 339 dbSNP
rs1175986637 345 dbSNP
rs895160428 347 dbSNP
rs929218174 347 dbSNP
rs1047681989 349 dbSNP
rs1292168364 349 dbSNP
rs1393482738 351 dbSNP
rs745507110 355 dbSNP
rs1292710766 357 dbSNP
rs1289486013 358 dbSNP
rs1012323705 361 dbSNP
rs1215541053 364 dbSNP
rs1387264518 366 dbSNP
rs1383794432 368 dbSNP
rs1318467456 372 dbSNP
rs1489414214 373 dbSNP
rs184794143 375 dbSNP
rs927873782 381 dbSNP
rs903682337 386 dbSNP
rs1364454283 395 dbSNP
rs1055380686 397 dbSNP
rs999733095 397 dbSNP
rs1030837502 402 dbSNP
rs1156693288 407 dbSNP
rs1346556085 409 dbSNP
rs894871825 412 dbSNP
rs1234731374 415 dbSNP
rs1353001490 419 dbSNP
rs546537271 421 dbSNP
rs370378603 424 dbSNP
rs1380561766 430 dbSNP
rs1223540134 433 dbSNP
rs568345526 443 dbSNP
rs1305275000 445 dbSNP
rs1189274167 446 dbSNP
rs1394192567 447 dbSNP
rs1454662376 448 dbSNP
rs986694789 455 dbSNP
rs1175515966 456 dbSNP
rs529230502 457 dbSNP
rs878921149 461 dbSNP
rs1399653612 462 dbSNP
rs1159141065 466 dbSNP
rs571570279 468 dbSNP
rs187650639 477 dbSNP
rs1324306619 479 dbSNP
rs999775632 491 dbSNP
rs1237934139 502 dbSNP
rs1439356115 505 dbSNP
rs1370810669 507 dbSNP
rs1442079159 508 dbSNP
rs1469590940 510 dbSNP
rs1175451417 512 dbSNP
rs1306332487 514 dbSNP
rs1029872744 515 dbSNP
rs1223322940 516 dbSNP
rs1172617784 521 dbSNP
rs1284989294 526 dbSNP
rs1373241773 526 dbSNP
rs1435991729 527 dbSNP
rs1371128131 530 dbSNP
rs973793045 531 dbSNP
rs1219567301 532 dbSNP
rs1353460591 534 dbSNP
rs780441564 536 dbSNP
rs539965273 538 dbSNP
rs929747206 539 dbSNP
rs1236314517 542 dbSNP
rs1316005793 548 dbSNP
rs974163959 550 dbSNP
rs1158652242 554 dbSNP
rs918585735 557 dbSNP
rs1279384389 560 dbSNP
rs951345777 561 dbSNP
rs1403090075 563 dbSNP
rs1437365089 565 dbSNP
rs747300006 567 dbSNP
rs983984462 568 dbSNP
rs1213000982 573 dbSNP
rs1240016787 574 dbSNP
rs1394735971 580 dbSNP
rs908051735 584 dbSNP
rs1192785342 591 dbSNP
rs74064058 592 dbSNP
rs773077233 593 dbSNP
rs759653359 596 dbSNP
rs767707465 598 dbSNP
rs1280217933 603 dbSNP
rs1375707491 607 dbSNP
rs1418153547 610 dbSNP
rs1226670700 616 dbSNP
rs369432100 619 dbSNP
rs1335667165 621 dbSNP
rs1215354201 624 dbSNP
rs1403105808 625 dbSNP
rs775800304 629 dbSNP
rs1437164266 630 dbSNP
rs1329691983 633 dbSNP
rs1369291751 635 dbSNP
rs1182520110 636 dbSNP
rs1234517254 637 dbSNP
rs567119513 641 dbSNP
rs148728541 646 dbSNP
rs895129209 659 dbSNP
rs948074477 660 dbSNP
rs1212882254 667 dbSNP
rs1043754572 669 dbSNP
rs1385816487 670 dbSNP
rs1259845546 686 dbSNP
rs1318560252 687 dbSNP
rs1213037218 688 dbSNP
rs1250889008 699 dbSNP
rs1453175204 703 dbSNP
rs1199127680 710 dbSNP
rs1241162402 712 dbSNP
rs1307262091 717 dbSNP
rs1172223778 723 dbSNP
rs1318420487 724 dbSNP
rs1426359117 728 dbSNP
rs555745635 730 dbSNP
rs1226020545 736 dbSNP
rs1266988755 738 dbSNP
rs1389009741 753 dbSNP
rs903896624 759 dbSNP
rs1388951754 761 dbSNP
rs999633629 762 dbSNP
rs1216125876 765 dbSNP
rs1031222334 766 dbSNP
rs1280141137 768 dbSNP
rs1047360934 769 dbSNP
rs1232593995 769 dbSNP
rs1002326428 773 dbSNP
rs1210227869 773 dbSNP
rs1283061229 773 dbSNP
rs1358121194 773 dbSNP
rs886120886 773 dbSNP
rs1178206362 774 dbSNP
rs1195447894 776 dbSNP
rs1013938803 777 dbSNP
rs1252912662 777 dbSNP
rs1474627466 777 dbSNP
rs1417608830 781 dbSNP
rs112648110 783 dbSNP
rs1310418749 783 dbSNP
rs1361246982 783 dbSNP
rs1414252696 783 dbSNP
rs1459714054 783 dbSNP
rs1491137277 783 dbSNP
rs201999529 783 dbSNP
rs770542789 783 dbSNP
rs1043533484 785 dbSNP
rs1181510014 785 dbSNP
rs902265419 787 dbSNP
rs574292651 789 dbSNP
rs1461850277 790 dbSNP
rs541434196 793 dbSNP
rs1348334774 796 dbSNP
rs934976504 796 dbSNP
rs1286371008 797 dbSNP
rs1485018466 798 dbSNP
rs371068821 798 dbSNP
rs1426104440 799 dbSNP
rs200614518 799 dbSNP
rs1188913787 805 dbSNP
rs201829254 805 dbSNP
rs371779212 805 dbSNP
rs1361426945 808 dbSNP
rs1375033439 809 dbSNP
rs1407650473 813 dbSNP
rs1287110079 816 dbSNP
rs1301202057 824 dbSNP
rs1404494592 825 dbSNP
rs1355559686 826 dbSNP
rs1235610686 828 dbSNP
rs1288348073 832 dbSNP
rs1051213067 835 dbSNP
rs890987920 846 dbSNP
rs12026443 854 dbSNP
rs1242056574 864 dbSNP
rs1309453868 871 dbSNP
rs891362311 873 dbSNP
rs1007583808 874 dbSNP
rs556946479 883 dbSNP
rs575234157 887 dbSNP
rs545535354 895 dbSNP
rs1018183989 904 dbSNP
rs1250445604 912 dbSNP
rs1456676928 913 dbSNP
rs142252375 918 dbSNP
rs1453969267 924 dbSNP
rs868257126 927 dbSNP
rs147957255 943 dbSNP
rs1167187832 949 dbSNP
rs1398037872 959 dbSNP
rs1411512818 959 dbSNP
rs1423218391 965 dbSNP
rs1036124191 971 dbSNP
rs1170836936 974 dbSNP
rs145966557 986 dbSNP
rs1427360986 988 dbSNP
rs991177860 1006 dbSNP
rs1384703928 1008 dbSNP
rs916413847 1012 dbSNP
rs192785560 1013 dbSNP
rs1375755850 1015 dbSNP
rs1257923783 1019 dbSNP
rs1416076549 1019 dbSNP
rs951182882 1020 dbSNP
rs372993464 1034 dbSNP
rs1281972614 1037 dbSNP
rs1201119123 1042 dbSNP
rs1239150691 1057 dbSNP
rs982567269 1077 dbSNP
rs1379040802 1084 dbSNP
rs1433787497 1104 dbSNP
rs923654521 1106 dbSNP
rs1298117717 1107 dbSNP
rs935101228 1109 dbSNP
rs561797520 1117 dbSNP
rs890822020 1119 dbSNP
rs375850203 1123 dbSNP
rs1456205355 1124 dbSNP
rs1294864067 1125 dbSNP
rs35455709 1133 dbSNP
rs942965119 1137 dbSNP
rs1486808609 1144 dbSNP
rs1208081187 1146 dbSNP
rs1275726086 1149 dbSNP
rs939524564 1154 dbSNP
rs1482860086 1156 dbSNP
rs992408946 1157 dbSNP
rs916868520 1158 dbSNP
rs948287082 1166 dbSNP
rs140159035 1169 dbSNP
rs887180410 1175 dbSNP
rs1193264122 1177 dbSNP
rs1261092434 1180 dbSNP
rs1003398158 1185 dbSNP
rs1194215022 1188 dbSNP
rs550675886 1205 dbSNP
rs1417096311 1207 dbSNP
rs1035686919 1219 dbSNP
rs903865826 1221 dbSNP
rs1350298099 1225 dbSNP
rs1395289055 1225 dbSNP
rs1296025772 1226 dbSNP
rs1361888327 1227 dbSNP
rs748716158 1229 dbSNP
rs1052553005 1244 dbSNP
rs1279323471 1247 dbSNP
rs991506999 1248 dbSNP
rs1226923998 1250 dbSNP
rs1331575530 1258 dbSNP
rs1358092089 1279 dbSNP
rs1322749506 1283 dbSNP
rs1216144271 1288 dbSNP
rs1284157669 1296 dbSNP
rs1489279942 1313 dbSNP
rs1217467523 1321 dbSNP
rs1432034880 1331 dbSNP
rs1291146830 1343 dbSNP
rs184233552 1346 dbSNP
rs1183581182 1347 dbSNP
rs1228103405 1349 dbSNP
rs1008047588 1350 dbSNP
rs189644852 1351 dbSNP
rs769860974 1361 dbSNP
rs1217715798 1362 dbSNP
rs773321698 1369 dbSNP
rs995404124 1371 dbSNP
rs1356970257 1374 dbSNP
rs1446429765 1376 dbSNP
rs1305168905 1389 dbSNP
rs530441725 1391 dbSNP
rs181895603 1393 dbSNP
rs1447664303 1400 dbSNP
rs566980730 1402 dbSNP
rs763141688 1409 dbSNP
rs956477317 1412 dbSNP
rs951109557 1418 dbSNP
rs1463528638 1420 dbSNP
rs1187665458 1425 dbSNP
rs1004352661 1426 dbSNP
rs912317730 1436 dbSNP
rs1478777382 1439 dbSNP
rs942327783 1452 dbSNP
rs1035485011 1460 dbSNP
rs1237989579 1462 dbSNP
rs960857966 1471 dbSNP
rs1239570957 1472 dbSNP
rs931589369 1474 dbSNP
rs534358383 1475 dbSNP
rs555950051 1489 dbSNP
rs1422428003 1491 dbSNP
rs1423775132 1493 dbSNP
rs1400775357 1495 dbSNP
rs1415747470 1496 dbSNP
rs1178799679 1497 dbSNP
rs1360272935 1507 dbSNP
rs34056062 1507 dbSNP
rs397863503 1507 dbSNP
rs1387060644 1513 dbSNP
rs1379644514 1514 dbSNP
rs992288128 1515 dbSNP
rs145569596 1524 dbSNP
rs1274555536 1547 dbSNP
rs1342875990 1550 dbSNP
rs1051110 1556 dbSNP
rs1223115314 1561 dbSNP
rs1326942367 1562 dbSNP
rs1002956364 1572 dbSNP
rs1279175617 1577 dbSNP
rs866454319 1586 dbSNP
rs1196715791 1587 dbSNP
rs1259726025 1590 dbSNP
rs969599020 1596 dbSNP
rs1458091505 1612 dbSNP
rs894565917 1614 dbSNP
rs1244637418 1619 dbSNP
rs1274485273 1621 dbSNP
rs1351746091 1634 dbSNP
rs1225519734 1636 dbSNP
rs979735840 1640 dbSNP
rs1169241441 1643 dbSNP
rs375811077 1646 dbSNP
rs967946272 1650 dbSNP
rs1268152983 1655 dbSNP
rs1323073114 1656 dbSNP
rs1329584247 1663 dbSNP
rs1208053652 1671 dbSNP
rs1273516007 1674 dbSNP
rs538566266 1684 dbSNP
rs766464212 1688 dbSNP
rs1275477811 1691 dbSNP
rs559320843 1694 dbSNP
rs1216708924 1695 dbSNP
rs1000820285 1697 dbSNP
rs1259989731 1697 dbSNP
rs367717045 1697 dbSNP
rs1209047225 1700 dbSNP
rs1287257078 1707 dbSNP
rs1452943825 1718 dbSNP
rs935383121 1737 dbSNP
rs1052937968 1740 dbSNP
rs1476594559 1740 dbSNP
rs912610260 1745 dbSNP
rs774664155 1746 dbSNP
rs115599295 1748 dbSNP
rs912269407 1751 dbSNP
rs1163069692 1752 dbSNP
rs963848845 1755 dbSNP
rs1389069832 1756 dbSNP
rs1407271681 1760 dbSNP
rs1304041778 1762 dbSNP
rs760318173 1766 dbSNP
rs574940280 1775 dbSNP
rs1409165452 1792 dbSNP
rs550279823 1794 dbSNP
rs1048331914 1797 dbSNP
rs1449826061 1811 dbSNP
rs763963395 1812 dbSNP
rs1326988939 1814 dbSNP
rs886772372 1825 dbSNP
rs1282190444 1826 dbSNP
rs919621746 1827 dbSNP
rs557389746 1835 dbSNP
rs1228534690 1845 dbSNP
rs752146717 1856 dbSNP
rs572618052 1864 dbSNP
rs1003917154 1870 dbSNP
rs1284875407 1875 dbSNP
rs1486990565 1882 dbSNP
rs1035772405 1886 dbSNP
rs753812583 1893 dbSNP
rs1012684080 1895 dbSNP
rs1448046431 1906 dbSNP
rs1023794310 1912 dbSNP
rs1187517420 1914 dbSNP
rs1047340924 1917 dbSNP
rs1474016707 1928 dbSNP
rs555936940 1929 dbSNP
rs1379929607 1933 dbSNP
rs1444678595 1934 dbSNP
rs1286479108 1949 dbSNP
rs114079217 1951 dbSNP
rs925590159 1958 dbSNP
rs1385823716 1959 dbSNP
rs147727577 1961 dbSNP
rs1332194734 1970 dbSNP
rs1273734227 1974 dbSNP
rs1358453611 1976 dbSNP
rs140671375 1977 dbSNP
rs1013028251 1980 dbSNP
rs764805836 1985 dbSNP
rs988122995 1996 dbSNP
rs1206872214 1997 dbSNP
rs998862099 2000 dbSNP
rs141032079 2010 dbSNP
rs1471978430 2016 dbSNP
rs1188123075 2017 dbSNP
rs1184627683 2030 dbSNP
rs1237997475 2031 dbSNP
rs1031302473 2032 dbSNP
rs1370683022 2035 dbSNP
rs956663579 2036 dbSNP
rs1472119337 2041 dbSNP
rs544533711 2042 dbSNP
rs1465614906 2046 dbSNP
rs1170684829 2051 dbSNP
rs562646069 2060 dbSNP
rs1404299861 2062 dbSNP
rs912582721 2064 dbSNP
rs750000666 2065 dbSNP
rs1008455053 2072 dbSNP
rs944099219 2078 dbSNP
rs1039793523 2079 dbSNP
rs921080117 2087 dbSNP
rs963751161 2089 dbSNP
rs757945464 2090 dbSNP
rs1230453124 2117 dbSNP
rs7544985 2119 dbSNP
rs1026604952 2121 dbSNP
rs572569650 2121 dbSNP
rs886996034 2126 dbSNP
rs1204918249 2132 dbSNP
rs1257809013 2150 dbSNP
rs184566041 2157 dbSNP
rs1370260952 2175 dbSNP
rs908756993 2180 dbSNP
rs1251537371 2182 dbSNP
rs938964071 2193 dbSNP
rs1196881279 2196 dbSNP
rs993386001 2201 dbSNP
rs10914537 2203 dbSNP
rs1056788669 2207 dbSNP
rs895511647 2212 dbSNP
rs1169945887 2213 dbSNP
rs150335813 2238 dbSNP
rs567891446 2246 dbSNP
rs1298335576 2255 dbSNP
rs1366496961 2261 dbSNP
rs1384759741 2262 dbSNP
rs905351135 2263 dbSNP
rs1339840803 2272 dbSNP
rs1224658566 2273 dbSNP
rs934620509 2274 dbSNP
rs1001005750 2283 dbSNP
rs181350424 2284 dbSNP
rs1272030913 2285 dbSNP
rs892359697 2286 dbSNP
rs1488259223 2293 dbSNP
rs1008174971 2303 dbSNP
rs1019858143 2313 dbSNP
rs755289514 2324 dbSNP
rs956956492 2327 dbSNP
rs750746343 2335 dbSNP
rs1257699405 2340 dbSNP
rs1421403572 2364 dbSNP
rs1478652342 2370 dbSNP
rs1441142157 2373 dbSNP
rs550402469 2374 dbSNP
rs899713927 2382 dbSNP
rs1349138642 2391 dbSNP
rs996637440 2399 dbSNP
rs1373926329 2400 dbSNP
rs988814373 2411 dbSNP
rs1019562161 2423 dbSNP
rs1398864623 2425 dbSNP
rs952475574 2426 dbSNP
rs982829510 2436 dbSNP
rs1216867136 2437 dbSNP
rs965374671 2438 dbSNP
rs781606942 2441 dbSNP
rs921383495 2443 dbSNP
rs1167166738 2445 dbSNP
rs1015281368 2450 dbSNP
rs931397720 2462 dbSNP
rs1435611938 2463 dbSNP
rs1321553983 2472 dbSNP
rs571616085 2474 dbSNP
rs1400183022 2475 dbSNP
rs539011635 2486 dbSNP
rs960554209 2489 dbSNP
rs1394152237 2501 dbSNP
rs1490517135 2504 dbSNP
rs1333428582 2505 dbSNP
rs993136266 2508 dbSNP
rs1365917247 2515 dbSNP
rs1486794595 2517 dbSNP
rs908385231 2530 dbSNP
rs939939079 2531 dbSNP
rs1421840447 2533 dbSNP
rs186353303 2534 dbSNP
rs1166403626 2537 dbSNP
rs1057094076 2541 dbSNP
rs1156277236 2551 dbSNP
rs895479084 2552 dbSNP
rs948400585 2560 dbSNP
rs1433483409 2561 dbSNP
rs1044090379 2566 dbSNP
rs1290038067 2566 dbSNP
rs1295180176 2567 dbSNP
rs748624183 2569 dbSNP
rs1394665525 2573 dbSNP
rs1317361611 2580 dbSNP
rs770335077 2581 dbSNP
rs1000374182 2587 dbSNP
rs1032484316 2611 dbSNP
rs201554236 2619 dbSNP
rs541606124 2619 dbSNP
rs57537827 2619 dbSNP
rs1216330584 2627 dbSNP
rs1236850776 2629 dbSNP
rs926003161 2630 dbSNP
rs1234600977 2631 dbSNP
rs892658466 2632 dbSNP
rs1257186153 2635 dbSNP
rs558166045 2638 dbSNP
rs1199451651 2646 dbSNP
rs80034706 2647 dbSNP
rs1438675371 2648 dbSNP
rs1019864453 2649 dbSNP
rs890494596 2654 dbSNP
rs9425952 2659 dbSNP
rs191106083 2660 dbSNP
rs996604507 2666 dbSNP
rs1339069537 2670 dbSNP
rs1384068864 2672 dbSNP
rs1026791675 2677 dbSNP
rs1307355715 2687 dbSNP
rs1224430297 2690 dbSNP
rs1375552271 2690 dbSNP
rs888176335 2691 dbSNP
rs1003992523 2692 dbSNP
rs1205540959 2695 dbSNP
rs149178112 2697 dbSNP
rs573735444 2714 dbSNP
rs1028284011 2715 dbSNP
rs1457202564 2725 dbSNP
rs1176322049 2726 dbSNP
rs1178518767 2727 dbSNP
rs959694974 2728 dbSNP
rs144941429 2744 dbSNP
rs562740741 2745 dbSNP
rs984641035 2750 dbSNP
rs908351566 2760 dbSNP
rs1179294269 2763 dbSNP
rs1437230271 2764 dbSNP
rs1465447608 2765 dbSNP
rs1329503828 2766 dbSNP
rs1318241834 2767 dbSNP
rs113692559 2772 dbSNP
rs1274316106 2774 dbSNP
rs1365658236 2776 dbSNP
rs12120374 2785 dbSNP
rs1225261028 2787 dbSNP
rs992735283 2788 dbSNP
rs978907103 2794 dbSNP
rs917136160 2795 dbSNP
rs948618589 2799 dbSNP
rs80323180 2801 dbSNP
rs926139910 2803 dbSNP
rs1438016097 2804 dbSNP
rs1220436069 2810 dbSNP
rs1244471537 2818 dbSNP
rs1481134547 2821 dbSNP
rs956311758 2824 dbSNP
rs1231861636 2836 dbSNP
rs1268252492 2841 dbSNP
rs1358823 2842 dbSNP
rs1044059265 2843 dbSNP
rs149034357 2849 dbSNP
rs1422160406 2850 dbSNP
rs944689538 2853 dbSNP
rs1039459073 2864 dbSNP
rs1207412677 2870 dbSNP
rs1323214039 2871 dbSNP
rs1363716379 2884 dbSNP
rs1406856770 2885 dbSNP
rs935754315 2898 dbSNP
rs921154124 2910 dbSNP
rs1339793467 2911 dbSNP
rs1216763712 2920 dbSNP
rs1053304295 2926 dbSNP
rs13142 2928 dbSNP
rs1339898375 2931 dbSNP
rs1227317762 2945 dbSNP
rs1287320588 2946 dbSNP
rs1490683716 2948 dbSNP
rs560506138 2950 dbSNP
rs1009725744 2953 dbSNP
rs1193346536 2956 dbSNP
rs181001262 2960 dbSNP
rs754525966 2968 dbSNP
rs549503397 2969 dbSNP
rs1162825422 2971 dbSNP
rs1383639412 2983 dbSNP
rs562714662 2991 dbSNP
rs1004458548 2993 dbSNP
rs531891721 2995 dbSNP
rs865860491 2996 dbSNP
rs748946624 3003 dbSNP
rs1320211539 3015 dbSNP
rs1326746959 3022 dbSNP
rs952845787 3028 dbSNP
rs1005630906 3037 dbSNP
rs1282026074 3048 dbSNP
rs550122692 3050 dbSNP
rs1156866823 3053 dbSNP
rs1361116985 3068 dbSNP
rs1013900439 3073 dbSNP
rs1246326578 3073 dbSNP
rs1022662261 3075 dbSNP
rs1203830740 3076 dbSNP
rs1319321398 3087 dbSNP
rs1387900650 3090 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 200081.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugcagucacugacGCGGGGGa 5'
                        | ||||| 
Target 5' ----------ccccCACCCCCa 3'
 		1 - 12
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugcagucacugacGCGGGGGa 5'
                        :|||||| 
Target 5' ---------cuuccUGCCCCCa 3'
 		1 - 13
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_175852 | 3UTR | UUCAUGGGUUUUUCUGCUUCCUGCCCCCACCCCCACAUGUGCAAUCCUCAAGAUUUGUCCUGAUUCUAUUUCCUGGCACCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_175852 | 3UTR | CCCCCACCCCCACAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_175852 | 3UTR | CUGCCUCUUUGGCUUCAUGGGUUUUUCUGCUUCCUGCCCCCACCCCCACAUGUGCAAUCCUCAAGAUUUGUCCUGAUUCUAUUUCCUGGCACCUCCCUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000373610.3 | 3UTR | CCCCCACCCCCACAUGUGCAAUCCUCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000373610.3 | 3UTR | CUUCCUGCCCCCACCCCCACAUGUGCAAUCCUCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
67 hsa-miR-4697-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT441332 C19orf26 CACN beta subunit associated regulatory protein 2 4
MIRT451390 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT452310 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT455043 MEN1 menin 1 2 2
MIRT455256 DDX39B DExD-box helicase 39B 2 10
MIRT461279 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 2
MIRT464945 TXLNA taxilin alpha 2 4
MIRT468043 SIK1 salt inducible kinase 1 2 2
MIRT472523 NACC1 nucleus accumbens associated 1 2 2
MIRT472929 MSN moesin 2 2
MIRT473247 MIDN midnolin 2 2
MIRT475828 HDGF heparin binding growth factor 2 2
MIRT478744 CS citrate synthase 2 2
MIRT480081 CALR calreticulin 2 2
MIRT483482 STMN3 stathmin 3 2 4
MIRT483643 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT483721 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT484539 BARHL1 BarH like homeobox 1 2 6
MIRT486041 WSCD1 WSC domain containing 1 2 4
MIRT486142 SIX5 SIX homeobox 5 2 6
MIRT486498 MYH11 myosin heavy chain 11 2 2
MIRT486977 STEAP3 STEAP3 metalloreductase 2 4
MIRT487279 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 4
MIRT487742 MIB2 mindbomb E3 ubiquitin protein ligase 2 2 2
MIRT487987 RXRB retinoid X receptor beta 2 2
MIRT488338 PAX2 paired box 2 2 2
MIRT488668 WWP2 WW domain containing E3 ubiquitin protein ligase 2 2 4
MIRT488752 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488812 TBC1D28 TBC1 domain family member 28 2 2
MIRT489380 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT489744 TACC3 transforming acidic coiled-coil containing protein 3 2 2
MIRT489960 GNB2 G protein subunit beta 2 2 2
MIRT490418 VPS51 VPS51, GARP complex subunit 2 4
MIRT490639 FEM1A fem-1 homolog A 2 2
MIRT491086 MSI1 musashi RNA binding protein 1 2 4
MIRT491298 VGF VGF nerve growth factor inducible 2 4
MIRT491366 SLC12A5 solute carrier family 12 member 5 2 2
MIRT492464 RASD1 ras related dexamethasone induced 1 2 4
MIRT492872 NFIX nuclear factor I X 2 2
MIRT492951 NEUROD2 neuronal differentiation 2 2 2
MIRT493704 H2AFX H2A histone family member X 2 2
MIRT493977 EIF1 eukaryotic translation initiation factor 1 2 4
MIRT500360 ZNF385A zinc finger protein 385A 2 2
MIRT501154 SLC10A7 solute carrier family 10 member 7 2 6
MIRT509625 RRP7A ribosomal RNA processing 7 homolog A 2 4
MIRT512232 ATG2A autophagy related 2A 2 8
MIRT529822 ARGFX arginine-fifty homeobox 2 4
MIRT531179 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT538971 BCL7A BCL tumor suppressor 7A 2 2
MIRT548357 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 4
MIRT553634 TJAP1 tight junction associated protein 1 2 2
MIRT558050 EVI5L ecotropic viral integration site 5 like 2 2
MIRT562548 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT568941 RUNX3 runt related transcription factor 3 2 2
MIRT569114 ONECUT3 one cut homeobox 3 2 2
MIRT573591 CERS1 ceramide synthase 1 2 2
MIRT619317 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT621202 ARPC1B actin related protein 2/3 complex subunit 1B 2 2
MIRT628844 FAM151B family with sequence similarity 151 member B 2 2
MIRT670497 LYRM4 LYR motif containing 4 2 2
MIRT670545 SHISA2 shisa family member 2 2 2
MIRT671026 PCDHB2 protocadherin beta 2 2 2
MIRT688989 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT709275 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT715084 ELOF1 elongation factor 1 homolog 2 2
MIRT718348 NPBWR1 neuropeptides B and W receptor 1 2 2
MIRT737406 MMP7 matrix metallopeptidase 7 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4697 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-4697-5p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4697-5p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (Bads-200, Bats-72, BCap37)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-4697-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4697-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4697-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4697-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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