miRTarBase - #MIRT465135


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pre-miRNA Information
pre-miRNA hsa-mir-3136   
Genomic Coordinates chr3: 69048958 - 69049035
Description Homo sapiens miR-3136 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3136-5p
Sequence 10| CUGACUGAAUAGGUAGGGUCAUU |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1478587998 4 dbSNP
rs912074637 12 dbSNP
rs1465866748 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TSC22D2   
Synonyms TILZ4a, TILZ4b, TILZ4c
Description TSC22 domain family member 2
Transcript NM_014779   
Expression
Putative miRNA Targets on TSC22D2
3'UTR of TSC22D2
(miRNA target sites are highlighted)		 
>TSC22D2|NM_014779|3'UTR
   1 AGCTTTCTTAAGCCTCATTAAGAAAAAAACTGAAAGCAATCTATCCTTGTGTGCCACTGGTGTTCTTTCCACTTTATACG
  81 AAAGCAAGTAGCCATGCTTTGGTTGTGTGTTTGGCCTTTTCAGTATTAGACAATCATTCTACAAGAGCTTTTCCTCTCTC
 161 TGAGATGTCATGCAGCGCTGTTGATGTCCAGTTCTATGTCATCAGTACACAAGGAGAATAATAGATGGGGTTTATTAAAG
 241 CGAGCAAAGTCTGCATTTTACCTGGTGCGCATGAGTGGGGTCTTTAAGAGTTTTGGTGGCTCTCCCATGTTTCCTATTAC
 321 CCATGGATTTACCCTGAGCCTTCCTATCACATTATAAATAACAGTTCATCTAAAGAGCCACTTTTCTTTCTGATTCAGTA
 401 ACATTTGCCTACATAAGTTTTCATTTATTTGTGTTTTATTTATTACAGGGCTGCTATTTTCATAATGTACATGAACAATG
 481 TCACAGAACTTTTTTAATTTTTTTGAATAATTATAAGTATCAGTAAAGGAAGTGAAAGACAGGATTGCATTTAATAGATA
 561 AAACGTTTAGGCAATAATTGAACAAAAGAATCCTGGCATATTTCTAACACTAATGGCAATTTACTTATGGTATTTATTTT
 641 CAGTAGTAAAGACCCAGCTTGAATGTAAATTTTGTATAGTGTAAGTATGAAGAACATAGTGCAACTGTACAGGTAGTCAC
 721 CAGTTATTGTGATATGATAAATAATTGGGCTATTTTGATGAAGAAAACTTTGTTCATTTGTTTCTACTTTCTAAGAGAAA
 801 TTGCCACGATTCCTCTGCTTTTCAACATTTCGTATGACTTTTTTTTCGGGTGGGAATAAAAAGCTGTGAAATTGTTCAAC
 881 CTACTTTGTAACCAAAGAAGCAAAGCTGTGTAATGGAGTTTGGTTTTTTTTTGTTGTTTTTTTTTTTTTGTCTTTTTTTT
 961 TTTTTATAATGCACATTCTTTATGTATTTTTATTTAGTGTTTTCTCAGTCACAATTTTCTTTACTGTCTAGCATGATCTG
1041 CATGACCTATAATCTTTGAACCACTTTCGTACCTCATGTTTTTATCCAGCACTCTTATTGTAATATGTACTAGTCTGTGA
1121 ACAATGTCAAATAAAAGAGAACGAACAGGTAGTTTGGTGGAGCTGAGCTAGTGTACAATACACTAGTTGTAAAAAAAAAA
1201 AAAAAAAAAAGTGAGCCATCTTTTGTTCATTTAAAATGGTGTTTTGAATTTCGTATGCAGAAAACGTTTTGTTACATTGC
1281 AGATTTTAATGTATTTAATAAATGCAACATGCAGATTAAGTGCAGTGTATACTGAGTATTTAAATTAAAATGTACATTTC
1361 ATAAATACAGTTTCAAAAGAAAGCATCATTTTGTGTATACTAACACATTAAGTGTATGTCAGAAATTGATGTATAAATAT
1441 ATATTTTAACATTTTCTGAAATTAAACTGCAGTTTTGTTGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuacugggAUGGAUAAGUCAGUc 5'
                  |:::|  ||||||| 
Target 5' ttatttagTGTTTTCTCAGTCAc 3'
 990 - 1012 147.00 -10.00
2 
miRNA  3' uuacuGGGAUGGAUAAGUCAGUc 5'
               :|:| |: ||||||| | 
Target 5' actttTCTTTCTGATTCAGTAAc 3'
 380 - 402 130.00 -10.22
3 
miRNA  3' uuacUGGGAUGGAUAAGUCA-GUc 5'
              :::|||: |  ||||| || 
Target 5' tccaGTTCTATGTCATCAGTACAc 3'
 187 - 210 123.00 -10.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30447907 5 COSMIC
COSN30450012 8 COSMIC
COSN30521163 8 COSMIC
COSN27000198 30 COSMIC
COSN30159998 33 COSMIC
COSN31553037 38 COSMIC
COSN30465406 47 COSMIC
COSN30494338 55 COSMIC
COSN14040133 81 COSMIC
COSN22914624 89 COSMIC
COSN30540579 115 COSMIC
COSN20792041 317 COSMIC
COSN28392820 406 COSMIC
COSN31551389 613 COSMIC
COSN31540633 809 COSMIC
COSN31545002 864 COSMIC
COSN22628809 866 COSMIC
COSN31569479 933 COSMIC
COSN20090910 934 COSMIC
COSN20099217 950 COSMIC
COSN20090912 951 COSMIC
COSN20090915 953 COSMIC
COSN30173201 965 COSMIC
COSN29962696 966 COSMIC
COSN6736092 1069 COSMIC
COSN30177148 1076 COSMIC
COSN31543948 1110 COSMIC
COSN31572206 1127 COSMIC
COSN31486646 1166 COSMIC
COSN20099218 1208 COSMIC
COSN9135949 1227 COSMIC
COSN16917278 2005 COSMIC
COSN25066957 2013 COSMIC
COSN25020204 2232 COSMIC
COSN1921243 3129 COSMIC
COSN27198800 3217 COSMIC
COSN28981485 3230 COSMIC
COSN29233208 3510 COSMIC
COSN4812432 3623 COSMIC
COSN21123548 3726 COSMIC
COSN25130282 3860 COSMIC
COSN20683645 3876 COSMIC
COSN25418590 4020 COSMIC
COSN17713724 4804 COSMIC
COSN30611302 4840 COSMIC
COSN30549303 4939 COSMIC
COSN5038647 4981 COSMIC
COSN30692315 5248 COSMIC
COSN30682088 5386 COSMIC
COSN27159009 5628 COSMIC
COSN6736093 6137 COSMIC
COSN14782899 6288 COSMIC
COSN22100403 6561 COSMIC
COSN30724582 6586 COSMIC
COSN30213171 6804 COSMIC
COSN1269755 6853 COSMIC
COSN1921244 7070 COSMIC
COSN30757055 7262 COSMIC
COSN21775646 7336 COSMIC
COSN30621660 7348 COSMIC
COSN30661670 7432 COSMIC
COSN30660438 7458 COSMIC
COSN17860091 7544 COSMIC
rs201481721 483 GWAS
rs199842413 1841 GWAS
rs16862676 2517 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1251166634 3 dbSNP
rs201338161 8 dbSNP
rs1295912763 13 dbSNP
rs771523745 17 dbSNP
rs768558955 24 dbSNP
rs1185318981 31 dbSNP
rs780947244 35 dbSNP
rs375386549 37 dbSNP
rs1169561766 38 dbSNP
rs769933959 40 dbSNP
rs773311462 42 dbSNP
rs1300195628 43 dbSNP
rs1397651549 49 dbSNP
rs1396019570 51 dbSNP
rs763039309 53 dbSNP
rs576007239 67 dbSNP
rs1480448495 76 dbSNP
rs907946584 78 dbSNP
rs1271160929 80 dbSNP
rs775008794 81 dbSNP
rs1403333683 95 dbSNP
rs973813357 97 dbSNP
rs1458254960 102 dbSNP
rs1481340855 103 dbSNP
rs1411805629 108 dbSNP
rs1175861710 110 dbSNP
rs1028500967 115 dbSNP
rs953865108 116 dbSNP
rs144546551 125 dbSNP
rs940817180 131 dbSNP
rs1187174085 134 dbSNP
rs1460132229 137 dbSNP
rs1250023961 148 dbSNP
rs972531006 153 dbSNP
rs919761501 154 dbSNP
rs1283392763 163 dbSNP
rs746309198 166 dbSNP
rs931207657 167 dbSNP
rs11537936 172 dbSNP
rs561829310 177 dbSNP
rs945283046 178 dbSNP
rs1321993422 180 dbSNP
rs1435114785 181 dbSNP
rs1345116553 184 dbSNP
rs527515952 191 dbSNP
rs550588073 192 dbSNP
rs775661370 196 dbSNP
rs949020544 197 dbSNP
rs902263751 199 dbSNP
rs1428717071 209 dbSNP
rs999311852 210 dbSNP
rs1189302547 211 dbSNP
rs547691162 215 dbSNP
rs925284567 218 dbSNP
rs893982958 225 dbSNP
rs1213619778 227 dbSNP
rs146353307 232 dbSNP
rs1453227148 242 dbSNP
rs1402620789 246 dbSNP
rs1244905950 247 dbSNP
rs936682698 254 dbSNP
rs996413126 260 dbSNP
rs1029643996 262 dbSNP
rs1055175671 266 dbSNP
rs1360731787 269 dbSNP
rs895239633 270 dbSNP
rs1439268856 272 dbSNP
rs955004597 274 dbSNP
rs1302938397 283 dbSNP
rs1423059284 286 dbSNP
rs987430990 287 dbSNP
rs1169530311 308 dbSNP
rs1435423602 309 dbSNP
rs1428122204 314 dbSNP
rs564417923 317 dbSNP
rs1293908494 319 dbSNP
rs1307081155 320 dbSNP
rs532525809 321 dbSNP
rs1247151651 322 dbSNP
rs886627844 324 dbSNP
rs1489817192 328 dbSNP
rs1005133519 334 dbSNP
rs1205486649 338 dbSNP
rs552245007 351 dbSNP
rs973460882 352 dbSNP
rs1292861252 358 dbSNP
rs1220397262 359 dbSNP
rs1246998371 367 dbSNP
rs919747464 384 dbSNP
rs1489877358 385 dbSNP
rs568129387 389 dbSNP
rs990697857 389 dbSNP
rs916465262 404 dbSNP
rs531685991 414 dbSNP
rs898131585 419 dbSNP
rs1246011088 447 dbSNP
rs1415042582 450 dbSNP
rs949323427 452 dbSNP
rs1198673038 465 dbSNP
rs1479402039 474 dbSNP
rs1253756185 476 dbSNP
rs1486164521 479 dbSNP
rs1187982656 480 dbSNP
rs200337684 481 dbSNP
rs201481721 482 dbSNP
rs1448713269 485 dbSNP
rs995586142 485 dbSNP
rs1028052073 486 dbSNP
rs953943675 487 dbSNP
rs1312325854 489 dbSNP
rs986597090 496 dbSNP
rs1019389498 515 dbSNP
rs966556480 521 dbSNP
rs548293341 531 dbSNP
rs1352828644 535 dbSNP
rs1422180418 537 dbSNP
rs977944293 541 dbSNP
rs1371457372 553 dbSNP
rs893582603 565 dbSNP
rs886545510 566 dbSNP
rs1449011005 569 dbSNP
rs1433520992 570 dbSNP
rs1287418533 586 dbSNP
rs996728057 586 dbSNP
rs773126739 593 dbSNP
rs1247249264 618 dbSNP
rs1159570211 620 dbSNP
rs1418354217 620 dbSNP
rs1248136805 625 dbSNP
rs1317404105 627 dbSNP
rs568301584 629 dbSNP
rs536783953 630 dbSNP
rs1242026031 642 dbSNP
rs890699081 654 dbSNP
rs534153227 657 dbSNP
rs1331863261 658 dbSNP
rs554042824 659 dbSNP
rs1238951145 660 dbSNP
rs1315562254 666 dbSNP
rs916613129 676 dbSNP
rs1285055995 681 dbSNP
rs1396867681 686 dbSNP
rs1382258954 692 dbSNP
rs949478114 693 dbSNP
rs747832344 703 dbSNP
rs1046513709 705 dbSNP
rs1437294326 711 dbSNP
rs1061239 722 dbSNP
rs962039096 728 dbSNP
rs778071090 735 dbSNP
rs1217854427 736 dbSNP
rs1361891804 742 dbSNP
rs994853991 751 dbSNP
rs570850350 753 dbSNP
rs958841410 757 dbSNP
rs1465913000 773 dbSNP
rs991060308 773 dbSNP
rs1433280723 787 dbSNP
rs766107378 798 dbSNP
rs940848679 802 dbSNP
rs1464255601 804 dbSNP
rs550349489 808 dbSNP
rs899436145 810 dbSNP
rs982029237 813 dbSNP
rs1230869412 816 dbSNP
rs1366088448 818 dbSNP
rs1244557664 819 dbSNP
rs1381613125 819 dbSNP
rs1382635314 826 dbSNP
rs1442421642 826 dbSNP
rs1295081122 828 dbSNP
rs995156739 832 dbSNP
rs148546053 833 dbSNP
rs1160629508 835 dbSNP
rs1161350759 838 dbSNP
rs1450923954 839 dbSNP
rs1191796952 841 dbSNP
rs1373192320 841 dbSNP
rs1346023744 842 dbSNP
rs183523428 848 dbSNP
rs1008391279 849 dbSNP
rs1157544085 851 dbSNP
rs1053477000 854 dbSNP
rs1019358342 864 dbSNP
rs1388617666 872 dbSNP
rs1207608186 875 dbSNP
rs529656451 880 dbSNP
rs1269692631 882 dbSNP
rs1225255862 909 dbSNP
rs999331908 910 dbSNP
rs1032191593 911 dbSNP
rs1405473173 922 dbSNP
rs1396711979 924 dbSNP
rs1431288004 924 dbSNP
rs1453061240 924 dbSNP
rs958181470 924 dbSNP
rs576002978 925 dbSNP
rs541544246 931 dbSNP
rs1378847616 933 dbSNP
rs1009369945 934 dbSNP
rs1480377675 934 dbSNP
rs145172355 936 dbSNP
rs11330414 937 dbSNP
rs1263812607 937 dbSNP
rs1347294967 937 dbSNP
rs1447802357 937 dbSNP
rs201497156 937 dbSNP
rs755957593 937 dbSNP
rs796502625 937 dbSNP
rs1380779782 938 dbSNP
rs1281170046 939 dbSNP
rs1444036662 939 dbSNP
rs1447574539 939 dbSNP
rs1050996504 940 dbSNP
rs1327851425 941 dbSNP
rs77535595 949 dbSNP
rs1403768148 950 dbSNP
rs369815824 950 dbSNP
rs375271796 950 dbSNP
rs796431684 951 dbSNP
rs1232647205 953 dbSNP
rs1427740821 953 dbSNP
rs75642934 953 dbSNP
rs878964591 953 dbSNP
rs1179995766 960 dbSNP
rs1444315809 965 dbSNP
rs1443277368 966 dbSNP
rs77364289 967 dbSNP
rs1222184098 969 dbSNP
rs1266131413 970 dbSNP
rs1261105455 971 dbSNP
rs1328429967 971 dbSNP
rs1204008424 978 dbSNP
rs1264786002 979 dbSNP
rs890624608 981 dbSNP
rs1351194245 982 dbSNP
rs1459651146 983 dbSNP
rs1186400436 985 dbSNP
rs1233162564 987 dbSNP
rs1470868493 993 dbSNP
rs1175018677 997 dbSNP
rs1411803836 998 dbSNP
rs1470594664 1000 dbSNP
rs1336832706 1005 dbSNP
rs1451189976 1011 dbSNP
rs1403257028 1013 dbSNP
rs1320915187 1015 dbSNP
rs1178942432 1017 dbSNP
rs1401776515 1020 dbSNP
rs187831497 1031 dbSNP
rs774070931 1034 dbSNP
rs190978725 1037 dbSNP
rs1183070632 1045 dbSNP
rs1036587166 1050 dbSNP
rs1249966011 1051 dbSNP
rs1337795178 1052 dbSNP
rs970786009 1062 dbSNP
rs141880383 1069 dbSNP
rs982569587 1070 dbSNP
rs1203097773 1097 dbSNP
rs898111849 1098 dbSNP
rs564280529 1099 dbSNP
rs570219193 1101 dbSNP
rs1244768729 1108 dbSNP
rs1379998545 1111 dbSNP
rs1271403526 1113 dbSNP
rs1432154645 1114 dbSNP
rs754873204 1116 dbSNP
rs543723997 1125 dbSNP
rs1316702652 1128 dbSNP
rs1426874745 1129 dbSNP
rs1366578593 1136 dbSNP
rs1163242950 1139 dbSNP
rs1037888727 1143 dbSNP
rs1392135186 1144 dbSNP
rs1242082542 1150 dbSNP
rs1187133223 1153 dbSNP
rs770208449 1155 dbSNP
rs183085494 1173 dbSNP
rs1213549511 1175 dbSNP
rs1490794938 1177 dbSNP
rs1349734724 1178 dbSNP
rs932207216 1181 dbSNP
rs1224054011 1183 dbSNP
rs1356779794 1184 dbSNP
rs1285188340 1186 dbSNP
rs1214590738 1189 dbSNP
rs74432476 1189 dbSNP
rs1361877329 1190 dbSNP
rs1191474424 1191 dbSNP
rs1269003050 1191 dbSNP
rs1302882436 1191 dbSNP
rs1409521897 1191 dbSNP
rs1417443052 1191 dbSNP
rs1481357235 1191 dbSNP
rs34952294 1191 dbSNP
rs376675183 1191 dbSNP
rs397874199 1191 dbSNP
rs397877472 1191 dbSNP
rs749744480 1191 dbSNP
rs752482363 1191 dbSNP
rs777546256 1191 dbSNP
rs869107465 1191 dbSNP
rs878894327 1191 dbSNP
rs879214590 1191 dbSNP
rs1342599103 1192 dbSNP
rs1199714041 1193 dbSNP
rs1273235384 1194 dbSNP
rs1439230136 1195 dbSNP
rs1202328186 1197 dbSNP
rs1250446896 1205 dbSNP
rs1480513311 1206 dbSNP
rs1198365921 1207 dbSNP
rs62767263 1207 dbSNP
rs1202224952 1209 dbSNP
rs1234190644 1210 dbSNP
rs1427866757 1210 dbSNP
rs959037768 1211 dbSNP
rs1050740008 1212 dbSNP
rs1022589102 1213 dbSNP
rs1270247481 1214 dbSNP
rs1398857724 1215 dbSNP
rs1408433121 1218 dbSNP
rs1225920629 1224 dbSNP
rs1307434461 1226 dbSNP
rs1324836751 1228 dbSNP
rs531768936 1229 dbSNP
rs1406912760 1230 dbSNP
rs146071445 1254 dbSNP
rs1023435698 1266 dbSNP
rs1232191986 1267 dbSNP
rs1007895181 1278 dbSNP
rs1178633102 1282 dbSNP
rs1270561619 1284 dbSNP
rs1340973680 1305 dbSNP
rs1040746183 1308 dbSNP
rs1429843203 1318 dbSNP
rs1175452511 1328 dbSNP
rs1431297475 1333 dbSNP
rs902284051 1337 dbSNP
rs923832992 1337 dbSNP
rs747253336 1338 dbSNP
rs956646417 1338 dbSNP
rs1273557230 1340 dbSNP
rs989543141 1351 dbSNP
rs999259747 1352 dbSNP
rs1263133126 1354 dbSNP
rs568262111 1355 dbSNP
rs1224138139 1361 dbSNP
rs527872024 1363 dbSNP
rs772824838 1367 dbSNP
rs1194260831 1375 dbSNP
rs1371400838 1376 dbSNP
rs1338801258 1377 dbSNP
rs1453384877 1380 dbSNP
rs1405439459 1381 dbSNP
rs1336068872 1383 dbSNP
rs1375154802 1384 dbSNP
rs1365364871 1390 dbSNP
rs1448110249 1396 dbSNP
rs1418161663 1399 dbSNP
rs957933438 1401 dbSNP
rs914920379 1403 dbSNP
rs1444774273 1404 dbSNP
rs1386133273 1407 dbSNP
rs1241961789 1410 dbSNP
rs1199280127 1413 dbSNP
rs1487111741 1417 dbSNP
rs931684155 1427 dbSNP
rs1426601093 1433 dbSNP
rs1050202678 1441 dbSNP
rs912033195 1442 dbSNP
rs1388433050 1453 dbSNP
rs1386157783 1467 dbSNP
rs1382192539 1471 dbSNP
rs1312973349 1494 dbSNP
rs1012568668 1502 dbSNP
rs1394252107 1506 dbSNP
rs188027625 1507 dbSNP
rs1327979846 1519 dbSNP
rs971098546 1521 dbSNP
rs1432687683 1524 dbSNP
rs1165133345 1533 dbSNP
rs1424864330 1543 dbSNP
rs1036512138 1544 dbSNP
rs1296390598 1547 dbSNP
rs1184713949 1560 dbSNP
rs1430827736 1562 dbSNP
rs1262966145 1567 dbSNP
rs749277869 1573 dbSNP
rs1294376585 1585 dbSNP
rs898080551 1593 dbSNP
rs191951009 1594 dbSNP
rs1049501275 1597 dbSNP
rs1263171557 1598 dbSNP
rs1327095205 1599 dbSNP
rs1296281661 1602 dbSNP
rs1381554039 1604 dbSNP
rs1356193022 1607 dbSNP
rs894480964 1610 dbSNP
rs1013396550 1611 dbSNP
rs907934077 1618 dbSNP
rs1264561534 1619 dbSNP
rs141404211 1622 dbSNP
rs1373143796 1632 dbSNP
rs962110671 1649 dbSNP
rs907308781 1650 dbSNP
rs1271538046 1653 dbSNP
rs1003373029 1657 dbSNP
rs534128948 1659 dbSNP
rs1030872133 1665 dbSNP
rs539709049 1667 dbSNP
rs920759106 1668 dbSNP
rs932204324 1688 dbSNP
rs1217965979 1698 dbSNP
rs989415539 1699 dbSNP
rs1284969277 1709 dbSNP
rs755858421 1710 dbSNP
rs1344635931 1715 dbSNP
rs1194761231 1717 dbSNP
rs1392754828 1719 dbSNP
rs1243919497 1723 dbSNP
rs953086105 1729 dbSNP
rs1297067695 1739 dbSNP
rs1446701617 1740 dbSNP
rs912164592 1742 dbSNP
rs1162704258 1743 dbSNP
rs1177778404 1743 dbSNP
rs943672587 1746 dbSNP
rs1376259995 1750 dbSNP
rs1040675462 1755 dbSNP
rs902211375 1757 dbSNP
rs1438565038 1766 dbSNP
rs911624386 1767 dbSNP
rs935077793 1769 dbSNP
rs944498875 1770 dbSNP
rs1456393978 1771 dbSNP
rs1454435083 1773 dbSNP
rs182801963 1780 dbSNP
rs1159046272 1783 dbSNP
rs1272827847 1783 dbSNP
rs187483485 1787 dbSNP
rs192447780 1788 dbSNP
rs893595120 1796 dbSNP
rs1012082708 1797 dbSNP
rs1319680909 1806 dbSNP
rs1382982173 1811 dbSNP
rs569527925 1812 dbSNP
rs1049337128 1829 dbSNP
rs894440386 1836 dbSNP
rs199842413 1840 dbSNP
rs1339359792 1844 dbSNP
rs1045797675 1845 dbSNP
rs1160603808 1854 dbSNP
rs1470641630 1856 dbSNP
rs906466595 1863 dbSNP
rs1177000912 1867 dbSNP
rs570825580 1870 dbSNP
rs998947432 1872 dbSNP
rs1327726039 1873 dbSNP
rs1014915634 1885 dbSNP
rs1264142980 1894 dbSNP
rs1462984305 1904 dbSNP
rs1180335935 1913 dbSNP
rs1441731780 1914 dbSNP
rs1276272133 1923 dbSNP
rs1255789906 1928 dbSNP
rs373810985 1928 dbSNP
rs111238275 1936 dbSNP
rs892316272 1945 dbSNP
rs973478453 1948 dbSNP
rs748909895 1962 dbSNP
rs1237477427 1968 dbSNP
rs1027747307 1974 dbSNP
rs1384414004 1976 dbSNP
rs1011210114 1982 dbSNP
rs1447966743 1991 dbSNP
rs1414043733 1998 dbSNP
rs953647661 2007 dbSNP
rs1320696237 2009 dbSNP
rs1401722941 2010 dbSNP
rs1022200222 2024 dbSNP
rs555490048 2026 dbSNP
rs140031561 2032 dbSNP
rs1385975458 2038 dbSNP
rs1426756720 2038 dbSNP
rs34765518 2038 dbSNP
rs953443261 2043 dbSNP
rs1472435323 2048 dbSNP
rs1235601474 2049 dbSNP
rs565551243 2055 dbSNP
rs541128956 2057 dbSNP
rs1285005631 2060 dbSNP
rs1214040136 2062 dbSNP
rs912075642 2069 dbSNP
rs944940603 2071 dbSNP
rs1227179026 2072 dbSNP
rs1401112998 2072 dbSNP
rs919397452 2075 dbSNP
rs977681274 2077 dbSNP
rs1340347557 2081 dbSNP
rs930842009 2083 dbSNP
rs201640455 2085 dbSNP
rs1031055342 2086 dbSNP
rs138186230 2086 dbSNP
rs71138445 2086 dbSNP
rs145249575 2092 dbSNP
rs916161574 2101 dbSNP
rs1403742888 2102 dbSNP
rs949019437 2105 dbSNP
rs1169619573 2112 dbSNP
rs1045726587 2113 dbSNP
rs1475677586 2113 dbSNP
rs1228308449 2115 dbSNP
rs557959105 2120 dbSNP
rs923597830 2125 dbSNP
rs1269237542 2129 dbSNP
rs935005334 2131 dbSNP
rs1274464564 2132 dbSNP
rs1215705889 2133 dbSNP
rs1317793979 2143 dbSNP
rs376984426 2143 dbSNP
rs1225663552 2146 dbSNP
rs1346538432 2151 dbSNP
rs137910993 2152 dbSNP
rs200881078 2154 dbSNP
rs77557880 2154 dbSNP
rs10690694 2155 dbSNP
rs63593560 2155 dbSNP
rs74860050 2155 dbSNP
rs760536089 2155 dbSNP
rs200115036 2156 dbSNP
rs1329567926 2159 dbSNP
rs1255580680 2169 dbSNP
rs1466084608 2175 dbSNP
rs1481100994 2177 dbSNP
rs114979767 2181 dbSNP
rs1481327071 2186 dbSNP
rs1425584040 2199 dbSNP
rs1043993404 2201 dbSNP
rs1487280239 2202 dbSNP
rs1457716400 2204 dbSNP
rs185730549 2204 dbSNP
rs202192401 2210 dbSNP
rs146737823 2212 dbSNP
rs377126332 2212 dbSNP
rs777625524 2212 dbSNP
rs965704765 2216 dbSNP
rs1300969831 2217 dbSNP
rs1429953942 2223 dbSNP
rs993179992 2225 dbSNP
rs947853295 2226 dbSNP
rs1026052637 2227 dbSNP
rs1446216052 2231 dbSNP
rs1398183335 2236 dbSNP
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rs34106738 5328 dbSNP
rs1242095946 5331 dbSNP
rs528829795 5333 dbSNP
rs963187769 5333 dbSNP
rs1193116050 5346 dbSNP
rs1423356317 5353 dbSNP
rs1363733216 5368 dbSNP
rs1476416592 5369 dbSNP
rs1033927170 5376 dbSNP
rs951485499 5386 dbSNP
rs1006076099 5399 dbSNP
rs1017102698 5404 dbSNP
rs992124216 5408 dbSNP
rs532236588 5412 dbSNP
rs766679249 5416 dbSNP
rs1373729649 5439 dbSNP
rs1169900805 5447 dbSNP
rs1447727386 5448 dbSNP
rs975595478 5466 dbSNP
rs1195397777 5468 dbSNP
rs1454565027 5472 dbSNP
rs1371028576 5473 dbSNP
rs1207718268 5474 dbSNP
rs1431537555 5474 dbSNP
rs1251529546 5477 dbSNP
rs148377812 5478 dbSNP
rs1339421960 5483 dbSNP
rs1306299544 5490 dbSNP
rs1235615903 5494 dbSNP
rs6803715 5496 dbSNP
rs1436991107 5498 dbSNP
rs1393487011 5505 dbSNP
rs954347511 5506 dbSNP
rs1297790934 5527 dbSNP
rs1276198789 5528 dbSNP
rs899756270 5528 dbSNP
rs1175471173 5543 dbSNP
rs569099791 5545 dbSNP
rs1232837309 5547 dbSNP
rs1376989840 5548 dbSNP
rs111634361 5549 dbSNP
rs190036776 5553 dbSNP
rs1250861498 5554 dbSNP
rs1180944458 5562 dbSNP
rs1043231012 5571 dbSNP
rs925776688 5573 dbSNP
rs112004510 5574 dbSNP
rs1344992346 5592 dbSNP
rs574617077 5593 dbSNP
rs9818469 5598 dbSNP
rs1336700353 5604 dbSNP
rs753140566 5608 dbSNP
rs959578632 5610 dbSNP
rs1408186530 5614 dbSNP
rs1189521950 5618 dbSNP
rs559749973 5621 dbSNP
rs1392099654 5630 dbSNP
rs992425272 5637 dbSNP
rs1447774764 5642 dbSNP
rs1170723019 5643 dbSNP
rs1024952075 5647 dbSNP
rs1047079162 5653 dbSNP
rs1364120053 5657 dbSNP
rs887147419 5679 dbSNP
rs1471373745 5689 dbSNP
rs1259161084 5690 dbSNP
rs187347874 5700 dbSNP
rs1395707765 5701 dbSNP
rs1254747215 5703 dbSNP
rs1207356708 5705 dbSNP
rs1405695152 5713 dbSNP
rs1226808406 5723 dbSNP
rs527271151 5723 dbSNP
rs925351005 5724 dbSNP
rs1391755985 5725 dbSNP
rs140391320 5726 dbSNP
rs1338730789 5732 dbSNP
rs1332151800 5735 dbSNP
rs989901451 5752 dbSNP
rs996981029 5758 dbSNP
rs1297961270 5772 dbSNP
rs1366716012 5773 dbSNP
rs1224641180 5776 dbSNP
rs1319707573 5776 dbSNP
rs932539908 5776 dbSNP
rs1029812780 5788 dbSNP
rs1051468857 5791 dbSNP
rs559114327 5792 dbSNP
rs868845994 5807 dbSNP
rs150357133 5809 dbSNP
rs1247948817 5812 dbSNP
rs1207273053 5828 dbSNP
rs1470092503 5837 dbSNP
rs777787160 5843 dbSNP
rs1468373080 5846 dbSNP
rs1209558745 5847 dbSNP
rs1250184105 5850 dbSNP
rs1445301853 5860 dbSNP
rs1410159222 5870 dbSNP
rs967455323 5878 dbSNP
rs1271947446 5882 dbSNP
rs1228230947 5883 dbSNP
rs1365922917 5884 dbSNP
rs1319769887 5885 dbSNP
rs1432697229 5904 dbSNP
rs1396342422 5911 dbSNP
rs995264392 5914 dbSNP
rs1372365735 5915 dbSNP
rs1473092757 5919 dbSNP
rs978495676 5920 dbSNP
rs1167085443 5933 dbSNP
rs1055271257 5938 dbSNP
rs1460774339 5939 dbSNP
rs925712800 5941 dbSNP
rs937129393 5943 dbSNP
rs1390425044 5945 dbSNP
rs79499371 5952 dbSNP
rs1317043106 5953 dbSNP
rs1340618501 5956 dbSNP
rs373276687 5959 dbSNP
rs1341518920 5966 dbSNP
rs1296812540 5974 dbSNP
rs1226026224 5975 dbSNP
rs949948300 5980 dbSNP
rs1047458311 5982 dbSNP
rs1032345162 5990 dbSNP
rs1334585741 5993 dbSNP
rs779752416 6000 dbSNP
rs1329037961 6001 dbSNP
rs941375738 6011 dbSNP
rs1229417065 6018 dbSNP
rs1038424874 6022 dbSNP
rs192106183 6044 dbSNP
rs1167269759 6070 dbSNP
rs1485016469 6081 dbSNP
rs72999319 6092 dbSNP
rs974809775 6094 dbSNP
rs1444263737 6099 dbSNP
rs768533039 6100 dbSNP
rs1477225594 6106 dbSNP
rs560039002 6117 dbSNP
rs1182739101 6118 dbSNP
rs764644871 6123 dbSNP
rs751616272 6124 dbSNP
rs114382366 6133 dbSNP
rs1021628243 6134 dbSNP
rs1279236271 6137 dbSNP
rs868756394 6139 dbSNP
rs978847608 6140 dbSNP
rs1280963101 6151 dbSNP
rs1409989457 6154 dbSNP
rs1376026 6170 dbSNP
rs1360292494 6177 dbSNP
rs1175947580 6198 dbSNP
rs1157707077 6203 dbSNP
rs1410569245 6206 dbSNP
rs931027587 6206 dbSNP
rs1472351615 6210 dbSNP
rs1249869938 6216 dbSNP
rs958428440 6221 dbSNP
rs991279015 6222 dbSNP
rs917081191 6230 dbSNP
rs949874304 6231 dbSNP
rs1311537337 6234 dbSNP
rs1209291481 6248 dbSNP
rs562708720 6251 dbSNP
rs1410744456 6252 dbSNP
rs772802151 6258 dbSNP
rs908467003 6259 dbSNP
rs1286013388 6262 dbSNP
rs1228765928 6264 dbSNP
rs1328136111 6268 dbSNP
rs531607808 6269 dbSNP
rs941313988 6275 dbSNP
rs1286037972 6277 dbSNP
rs1038756200 6283 dbSNP
rs1234644741 6284 dbSNP
rs899882390 6291 dbSNP
rs1379198383 6293 dbSNP
rs1302807289 6302 dbSNP
rs1446379155 6305 dbSNP
rs1347327170 6306 dbSNP
rs1290611312 6308 dbSNP
rs183894922 6312 dbSNP
rs1410082013 6314 dbSNP
rs1167310702 6323 dbSNP
rs1315563655 6332 dbSNP
rs894926276 6333 dbSNP
rs1181226348 6336 dbSNP
rs1482269366 6342 dbSNP
rs1051131456 6349 dbSNP
rs550056942 6350 dbSNP
rs1464257709 6375 dbSNP
rs1265877648 6376 dbSNP
rs1010169042 6377 dbSNP
rs1321797257 6380 dbSNP
rs1208861748 6381 dbSNP
rs1278018765 6382 dbSNP
rs1021179300 6387 dbSNP
rs904091106 6410 dbSNP
rs1364779180 6411 dbSNP
rs999788291 6428 dbSNP
rs1182887167 6432 dbSNP
rs1001149293 6461 dbSNP
rs1252404556 6461 dbSNP
rs1033091164 6464 dbSNP
rs1434858482 6490 dbSNP
rs958396974 6505 dbSNP
rs991205244 6506 dbSNP
rs1180622433 6514 dbSNP
rs1458555952 6525 dbSNP
rs1349503250 6527 dbSNP
rs115482306 6539 dbSNP
rs116365190 6540 dbSNP
rs765187708 6542 dbSNP
rs1171200613 6557 dbSNP
rs983006224 6563 dbSNP
rs1448675745 6567 dbSNP
rs1245894779 6569 dbSNP
rs1211278647 6576 dbSNP
rs766027337 6577 dbSNP
rs1264484884 6579 dbSNP
rs747951458 6581 dbSNP
rs1218789861 6586 dbSNP
rs1029028560 6597 dbSNP
rs1276016901 6599 dbSNP
rs1228230267 6600 dbSNP
rs1375308590 6605 dbSNP
rs1306161959 6610 dbSNP
rs78157302 6613 dbSNP
rs987001693 6615 dbSNP
rs941272580 6623 dbSNP
rs1371590635 6627 dbSNP
rs1391227574 6628 dbSNP
rs961562313 6630 dbSNP
rs972695188 6636 dbSNP
rs759954932 6645 dbSNP
rs921229152 6650 dbSNP
rs1200818473 6651 dbSNP
rs1433523204 6655 dbSNP
rs932656863 6668 dbSNP
rs1279687167 6669 dbSNP
rs1051106281 6682 dbSNP
rs1047412 6688 dbSNP
rs990519811 6695 dbSNP
rs1251837840 6714 dbSNP
rs916329531 6717 dbSNP
rs1340753879 6723 dbSNP
rs1258256354 6729 dbSNP
rs912660959 6734 dbSNP
rs1234485923 6746 dbSNP
rs1311929188 6750 dbSNP
rs949165118 6758 dbSNP
rs1393289816 6759 dbSNP
rs1351195144 6760 dbSNP
rs777724510 6761 dbSNP
rs1368673629 6764 dbSNP
rs1042932190 6770 dbSNP
rs904062284 6779 dbSNP
rs1174223455 6786 dbSNP
rs1205751432 6789 dbSNP
rs1046965109 6790 dbSNP
rs902691049 6791 dbSNP
rs1253061597 6792 dbSNP
rs935555837 6798 dbSNP
rs1180883881 6819 dbSNP
rs1479509677 6821 dbSNP
rs1481776035 6825 dbSNP
rs1001518904 6829 dbSNP
rs1053942063 6830 dbSNP
rs1201490096 6852 dbSNP
rs894097851 6853 dbSNP
rs1055393548 6857 dbSNP
rs188832259 6860 dbSNP
rs996133373 6863 dbSNP
rs207463881 6866 dbSNP
rs1230603983 6875 dbSNP
rs1455313959 6884 dbSNP
rs1028954890 6887 dbSNP
rs894108944 6888 dbSNP
rs1226702967 6889 dbSNP
rs1342291099 6901 dbSNP
rs1008997797 6910 dbSNP
rs1396478355 6921 dbSNP
rs1173134463 6926 dbSNP
rs867799367 6930 dbSNP
rs539126229 6932 dbSNP
rs1458593056 6934 dbSNP
rs973007300 6936 dbSNP
rs1461742378 6962 dbSNP
rs192613231 6964 dbSNP
rs1024005031 6965 dbSNP
rs1369620920 6969 dbSNP
rs971116050 6970 dbSNP
rs1423799477 6981 dbSNP
rs76324703 6984 dbSNP
rs753228433 6987 dbSNP
rs1267765845 6995 dbSNP
rs1207012062 7045 dbSNP
rs1365996209 7056 dbSNP
rs569597516 7077 dbSNP
rs184233488 7081 dbSNP
rs1284916995 7094 dbSNP
rs962582577 7104 dbSNP
rs1339846634 7105 dbSNP
rs1305696165 7106 dbSNP
rs1226339445 7107 dbSNP
rs756576764 7111 dbSNP
rs1469703374 7117 dbSNP
rs1319479453 7123 dbSNP
rs974356562 7130 dbSNP
rs1211402559 7141 dbSNP
rs554868876 7142 dbSNP
rs1398532495 7148 dbSNP
rs921198090 7150 dbSNP
rs954018748 7157 dbSNP
rs3177575 7161 dbSNP
rs981900451 7170 dbSNP
rs1252041637 7173 dbSNP
rs923707426 7179 dbSNP
rs1187769494 7187 dbSNP
rs574093962 7191 dbSNP
rs1191004377 7198 dbSNP
rs757274793 7199 dbSNP
rs1247735708 7203 dbSNP
rs1187053338 7208 dbSNP
rs1453609115 7208 dbSNP
rs986752043 7214 dbSNP
rs1053922203 7233 dbSNP
rs894024202 7236 dbSNP
rs932245673 7244 dbSNP
rs764200666 7253 dbSNP
rs1230438290 7255 dbSNP
rs1365674352 7261 dbSNP
rs1050359750 7263 dbSNP
rs1166196550 7263 dbSNP
rs1332497422 7264 dbSNP
rs746525024 7271 dbSNP
rs912587285 7275 dbSNP
rs1404266090 7276 dbSNP
rs1363120397 7278 dbSNP
rs1009337368 7284 dbSNP
rs73167547 7304 dbSNP
rs1390099131 7311 dbSNP
rs1325419001 7313 dbSNP
rs897939085 7314 dbSNP
rs1479196969 7321 dbSNP
rs1042513258 7332 dbSNP
rs1198382539 7337 dbSNP
rs1449946362 7339 dbSNP
rs925411630 7343 dbSNP
rs936858850 7345 dbSNP
rs1205938287 7352 dbSNP
rs1287202282 7356 dbSNP
rs1273782339 7370 dbSNP
rs1212633953 7371 dbSNP
rs1275104670 7372 dbSNP
rs1435223881 7374 dbSNP
rs1361426861 7376 dbSNP
rs1343242971 7378 dbSNP
rs1309391178 7379 dbSNP
rs1055363901 7380 dbSNP
rs1370535975 7384 dbSNP
rs554700240 7393 dbSNP
rs1213915463 7395 dbSNP
rs1293875328 7401 dbSNP
rs1416553600 7404 dbSNP
rs1426236727 7410 dbSNP
rs1172230510 7417 dbSNP
rs1336645760 7421 dbSNP
rs1026822245 7424 dbSNP
rs895385986 7425 dbSNP
rs1183032196 7431 dbSNP
rs1013866981 7441 dbSNP
rs1272074502 7443 dbSNP
rs762434698 7445 dbSNP
rs553741500 7451 dbSNP
rs1045420445 7452 dbSNP
rs1443930822 7457 dbSNP
rs757480245 7458 dbSNP
rs1004334906 7460 dbSNP
rs1321024900 7470 dbSNP
rs1015344951 7477 dbSNP
rs1289809942 7478 dbSNP
rs1228497203 7481 dbSNP
rs1349297686 7484 dbSNP
rs1296966678 7485 dbSNP
rs1023281861 7500 dbSNP
rs1239859174 7500 dbSNP
rs1333994771 7500 dbSNP
rs1391167416 7503 dbSNP
rs962837606 7503 dbSNP
rs1160115549 7506 dbSNP
rs1182932071 7514 dbSNP
rs1260259927 7519 dbSNP
rs1175423730 7520 dbSNP
rs188423371 7528 dbSNP
rs776107123 7528 dbSNP
rs1028143236 7529 dbSNP
rs1474409942 7539 dbSNP
rs1459775578 7545 dbSNP
rs1269667473 7549 dbSNP
rs1208896507 7553 dbSNP
rs1164662562 7555 dbSNP
rs1182872031 7556 dbSNP
rs1188956531 7556 dbSNP
rs1249608034 7556 dbSNP
rs1349111507 7556 dbSNP
rs1414475716 7556 dbSNP
rs1442552433 7556 dbSNP
rs1485380760 7556 dbSNP
rs200132826 7556 dbSNP
rs35328902 7556 dbSNP
rs374062794 7556 dbSNP
rs398052359 7556 dbSNP
rs66898777 7556 dbSNP
rs71672299 7556 dbSNP
rs780465256 7556 dbSNP
rs869229542 7556 dbSNP
rs1412897980 7557 dbSNP
rs1258546439 7558 dbSNP
rs1223190949 7560 dbSNP
rs1402647980 7561 dbSNP
rs1321742059 7562 dbSNP
rs1289827094 7567 dbSNP
rs1244331987 7575 dbSNP
rs953947531 7576 dbSNP
rs1157278034 7577 dbSNP
rs1344653269 7586 dbSNP
rs982211983 7586 dbSNP
rs1295457473 7589 dbSNP
rs1448911296 7589 dbSNP
rs1437321875 7591 dbSNP
rs1313359362 7598 dbSNP
rs923713154 7602 dbSNP
rs986719662 7612 dbSNP
rs1422733234 7622 dbSNP
rs545906161 7630 dbSNP
rs1412638759 7638 dbSNP
rs956665116 7642 dbSNP
rs989576161 7642 dbSNP
rs1019567191 7647 dbSNP
rs1259254804 7666 dbSNP
rs915425175 7681 dbSNP
rs966745119 7686 dbSNP
rs978544888 7689 dbSNP
rs925410602 7692 dbSNP
rs76415295 7703 dbSNP
rs1275949528 7707 dbSNP
rs1211021191 7709 dbSNP
rs1303685827 7729 dbSNP
rs149500744 7732 dbSNP
rs1301450443 7734 dbSNP
rs1484983329 7743 dbSNP
rs1187941047 7750 dbSNP
rs1308503432 7756 dbSNP
rs1461319528 7757 dbSNP
rs879813484 7758 dbSNP
rs1252980637 7767 dbSNP
rs912159314 7774 dbSNP
rs944717146 7782 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuacugggauGGAUAAGUCAGUc 5'
                    ::|  ||||||| 
Target 5' ----------UUUUCUCAGUCAc 3'
 		1 - 13
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_014779 | 3UTR | ACAAUUUUCUUUACUGUCUAGCAUGAUCUGCAUGACCUAUAAUCUUUGAACCACUUUCGUACCUCAUGUUUUUAUCCAGCACUCUUAUUGUAAUAUGUACUAGUCUGUGAACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_014779 | 3UTR | ACAAUUUUCUUUACUGUCUAGCAUGAUCUGCAUGACCUAUAAUCUUUGAACCACUUUCGUACCUCAUGUUUUUAUCCAGCACUCUUAUUGUAAUAUGUACUAGUCUGUGAACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_014779 | 3UTR | ACAAUUUUCUUUACUGUCUAGCAUGAUCUGCAUGACCUAUAAUCUUUGAACCACUUUCGUACCUCAUGUUUUUAUCCAGCACUCUUAUUGUAAUAUGUACUAGUCUGUGAACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000361875.3 | 3UTR | UUUUCUCAGUCACAAUUUUCUUUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
CHOL 0.999 0.01 1.000 0.5 3 Click to see details
UCEC 0.476 0.04 0.613 0.01 14 Click to see details
KIRP -0.441 0.04 -0.271 0.15 16 Click to see details
BRCA 0.293 0.06 0.157 0.2 30 Click to see details
LUSC -0.305 0.08 -0.327 0.07 22 Click to see details
HNSC -0.283 0.1 -0.277 0.11 22 Click to see details
KICH 0.354 0.11 0.284 0.16 14 Click to see details
PAAD 0.901 0.14 0.500 0.33 3 Click to see details
THCA -0.166 0.14 -0.116 0.23 43 Click to see details
ESCA 0.883 0.16 0.500 0.33 3 Click to see details
KIRC 0.15 0.33 0.191 0.29 11 Click to see details
BLCA 0.443 0.35 0.500 0.33 3 Click to see details
PRAD -0.076 0.4 0.029 0.46 14 Click to see details
LIHC 0.041 0.43 0.102 0.32 23 Click to see details
STAD -0.057 0.43 -0.308 0.17 12 Click to see details
STAD -0.057 0.43 -0.308 0.17 12 Click to see details
STAD -0.057 0.43 -0.308 0.17 12 Click to see details
STAD -0.057 0.43 -0.308 0.17 12 Click to see details
84 hsa-miR-3136-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081899 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT185493 SRP9 signal recognition particle 9 2 2
MIRT207226 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT246179 TXNIP thioredoxin interacting protein 2 4
MIRT347685 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT444157 ZNF701 zinc finger protein 701 2 2
MIRT444505 ZNF525 zinc finger protein 525 2 2
MIRT444683 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT445131 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT446184 FGF1 fibroblast growth factor 1 2 2
MIRT447946 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT449366 ANTXR2 anthrax toxin receptor 2 2 2
MIRT449774 SULF2 sulfatase 2 2 2
MIRT450096 ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2 2
MIRT450903 CADM2 cell adhesion molecule 2 2 4
MIRT455645 YARS tyrosyl-tRNA synthetase 2 2
MIRT465135 TSC22D2 TSC22 domain family member 2 2 2
MIRT476177 GOLGA8A golgin A8 family member A 2 8
MIRT483978 PANK1 pantothenate kinase 1 2 10
MIRT497016 INO80B INO80 complex subunit B 2 2
MIRT497450 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT497626 ZNF576 zinc finger protein 576 2 2
MIRT498187 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT504036 TOMM5 translocase of outer mitochondrial membrane 5 2 2
MIRT507106 GOLGA8B golgin A8 family member B 2 4
MIRT507900 CALM2 calmodulin 2 2 6
MIRT508802 MTPN myotrophin 2 6
MIRT510407 ZNF268 zinc finger protein 268 2 4
MIRT516297 F8A2 coagulation factor VIII associated 2 2 2
MIRT516323 F8A3 coagulation factor VIII associated 3 2 2
MIRT528028 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT529396 ICK intestinal cell kinase 2 2
MIRT534463 SCD stearoyl-CoA desaturase 2 4
MIRT535438 PDE4D phosphodiesterase 4D 2 2
MIRT538187 DBN1 drebrin 1 2 2
MIRT547386 MOB1A MOB kinase activator 1A 2 2
MIRT548180 FOXC1 forkhead box C1 2 2
MIRT561585 SKI SKI proto-oncogene 2 2
MIRT569449 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT573314 RFC5 replication factor C subunit 5 2 2
MIRT574762 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT575975 Fem1a feminization 1 homolog a (C. elegans) 2 5
MIRT575999 Zfp106 zinc finger protein 106 1 1
MIRT576277 Cd59a CD59a antigen 1 1
MIRT606772 KIAA0040 KIAA0040 2 5
MIRT606833 FEM1A fem-1 homolog A 2 7
MIRT608302 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT609269 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT609405 SLC25A45 solute carrier family 25 member 45 2 2
MIRT609603 TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein 2 2
MIRT610105 IL17REL interleukin 17 receptor E like 2 3
MIRT610327 SSX5 SSX family member 5 2 2
MIRT610610 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT611066 ZNF621 zinc finger protein 621 2 2
MIRT611492 ZNF440 zinc finger protein 440 2 2
MIRT611931 ZNF106 zinc finger protein 106 2 3
MIRT612239 MICALL1 MICAL like 1 2 2
MIRT612451 SMOC1 SPARC related modular calcium binding 1 2 4
MIRT612567 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 2 2
MIRT613111 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT614946 KAT6B lysine acetyltransferase 6B 2 2
MIRT615100 BNC2 basonuclin 2 2 2
MIRT616424 FAM126B family with sequence similarity 126 member B 2 2
MIRT617839 FMO4 flavin containing monooxygenase 4 2 2
MIRT618499 HSPD1 heat shock protein family D (Hsp60) member 1 2 2
MIRT619230 FBXL4 F-box and leucine rich repeat protein 4 2 2
MIRT624202 DCP2 decapping mRNA 2 2 4
MIRT630405 MTX3 metaxin 3 2 2
MIRT640327 DAAM2 dishevelled associated activator of morphogenesis 2 2 2
MIRT642779 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT654363 RBM23 RNA binding motif protein 23 2 2
MIRT654482 RANBP2 RAN binding protein 2 2 2
MIRT656336 MED28 mediator complex subunit 28 2 2
MIRT662856 UPF3A UPF3A, regulator of nonsense mediated mRNA decay 2 2
MIRT666894 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT669526 AP5M1 adaptor related protein complex 5 mu 1 subunit 2 2
MIRT671561 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT707042 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT717063 MTMR6 myotubularin related protein 6 2 2
MIRT717223 SH2D5 SH2 domain containing 5 2 2
MIRT719867 CYP4F11 cytochrome P450 family 4 subfamily F member 11 2 2
MIRT719967 RBX1 ring-box 1 2 2
MIRT723594 FKRP fukutin related protein 2 2
MIRT725081 VCPIP1 valosin containing protein interacting protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3136-5p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3136-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3136-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-3136-5p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-3136-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-3136-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3136-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)

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