miRTarBase - #MIRT466536


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pre-miRNA Information
pre-miRNA hsa-mir-4419b   
Genomic Coordinates chr12: 128244506 - 128244573
Description Homo sapiens miR-4419b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4419b
Sequence 42| GAGGCUGAAGGAAGAUGG |59
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TBXA2R   
Synonyms BDPLT13, TXA2-R
Description thromboxane A2 receptor
Transcript NM_001060   
Other Transcripts NM_201636   
Expression
Putative miRNA Targets on TBXA2R
3'UTR of TBXA2R
(miRNA target sites are highlighted)		 
>TBXA2R|NM_001060|3'UTR
   1 GAAGTGGACAGAGCGCCCCTCCCGCGCCTTTCCGCGGAGCCCTTGGCCCCTCGGACAGCCCATCTGCCTGTTCTGAGGAT
  81 TCAGGGGCTGGGGGTGCTGGATGGACAGTGGGCATCAGCAGCAGGGTTTTGGGTTGACCCCAATCCAACCCGGGGACCCC
 161 CAACTCCTCCCTGATCCTTTTACCAAGCACTCTCCCTTCCTCGGCCCCTTTTTCCCATCCAGAGCTCCCACCCCTTCTCT
 241 GCGTCCCTCCCAACCCCAGGAAGGGCATGCAGACATTGGAAGAGGGTCTTGCATTGCTATTTTTTTTTTTAGACGGAGTC
 321 TTGCTCTGTCCCCCAGGCTGGAGTGCAGTGGCGCAATCTCAGCTCACTGCAACCTCCACCTCCCGGGTTCAAGCGATTCT
 401 CCTGCCTCAGCCTCCTGAGTAGCTGGGACTATAGGCGCGCGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGAC
 481 GGGGTTTCACCGTGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATTCACCAGCCTCAGCCTCCCAAAGTGCTG
 561 GGATCACAGGCATGAACCACCACACCTGGCCATTTTTTTTTTTTTTTTTAGACGGAGTCTCACTCTGTGGCCCAGCCTGG
 641 AGTACAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGATTCTCGTGCCTCAGCCTCCCGAGCA
 721 GCTGGGATTACAGGCGTAAGCCACTGCGCCCGGCCTTGCATGCTCTTTGACCCTGAATTTGACCTACTTGCTGGGGTACA
 801 GTTGCTTCCTTTTGAACCTCCAACAGGGAAGGCTCTGTCCAGAAAGGATTGAATGTGAACGGGGGCACCCCCTTTTCTTG
 881 CCAAAATATATCTCTGCCTTTGGTTTTATTTTCCTTTGGGTCCAGAAGTTTTCAATCTCTGGAGTTTGTGCATTGGGCCT
 961 CACCCGGAGCAGACGAGGGCAGGGCTGGGAAGGATGGGGAGGGACATAGAGGATTCGGTTCCTCCCCCACCTTGTTTCTT
1041 GAGTGTTTCCTAATCACTTGATGGGTGGTACCACCTAGAATTCTTCCAGCAGCCTGTAATGGGAGGGCTACAGGTTAGCC
1121 CTGGAACCTGCAATCAAACCACCTTTGAATCTGTGTGTCATTAAAAGTAGATATAAATGGGCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggUAGAAGGA---AGUCGGAg 5'
            ||: ||||   ||||||| 
Target 5' cgATTCTCCTGCCTCAGCCTc 3'
 394 - 414 156.00 -17.50
2 
miRNA  3' gguAGAAGGAAGUCGGAg 5'
             || | | ||||||| 
Target 5' ttcTCGTGCCTCAGCCTc 3'
 696 - 713 151.00 -17.20
3 
miRNA  3' ggUAGAAGGAAGUCGGAg 5'
            | |  || ||||||| 
Target 5' tcACCAGCC-TCAGCCTc 3'
 533 - 549 143.00 -19.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1207313 610 ClinVar
263264 654 ClinVar
263265 680 ClinVar
COSN30187986 14 COSMIC
COSN7125398 15 COSMIC
COSN28224864 23 COSMIC
COSN31526930 27 COSMIC
COSN18742161 34 COSMIC
COSN4894577 35 COSMIC
COSN24314798 41 COSMIC
COSN30705920 42 COSMIC
COSN31975748 47 COSMIC
COSN26551840 56 COSMIC
COSN31964385 58 COSMIC
COSN31606822 87 COSMIC
COSN31965875 112 COSMIC
COSN30754025 131 COSMIC
COSN7125397 152 COSMIC
COSN28765058 164 COSMIC
COSN31522221 169 COSMIC
COSN5760111 217 COSMIC
COSN31592683 243 COSMIC
COSN9356048 251 COSMIC
COSN31529996 301 COSMIC
COSN1767140 360 COSMIC
COSN6143349 384 COSMIC
COSN22979805 441 COSMIC
COSN5760109 540 COSMIC
COSM6390972 642 COSMIC
COSM6360879 648 COSMIC
COSM4600491 653 COSMIC
COSM6434093 653 COSMIC
COSM5460174 654 COSMIC
COSM9594199 662 COSMIC
COSM3396338 677 COSMIC
COSM4131670 677 COSMIC
COSM1189771 683 COSMIC
COSM5897200 689 COSMIC
COSM3197835 693 COSMIC
COSM5899772 694 COSMIC
COSM7232025 701 COSMIC
COSM9303682 715 COSMIC
COSM6457357 719 COSMIC
COSM5940951 730 COSMIC
COSM3197832 751 COSMIC
COSM3197831 761 COSMIC
COSM5927875 775 COSMIC
COSM5788585 791 COSMIC
COSM9136972 794 COSMIC
COSM9148995 800 COSMIC
COSM8465359 809 COSMIC
COSM9381028 835 COSMIC
COSM3197828 846 COSMIC
COSN31611593 892 COSMIC
COSN15662175 1016 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs544022196 1 dbSNP
rs774470557 2 dbSNP
rs1281149007 4 dbSNP
rs771062632 5 dbSNP
rs929091830 6 dbSNP
rs1242604992 8 dbSNP
rs1186822491 9 dbSNP
rs201311763 11 dbSNP
rs1280523543 13 dbSNP
rs565561409 14 dbSNP
rs199890053 15 dbSNP
rs747968063 17 dbSNP
rs373366086 18 dbSNP
rs1356724540 19 dbSNP
rs201969840 21 dbSNP
rs1283071962 22 dbSNP
rs754919407 23 dbSNP
rs200736764 24 dbSNP
rs779612562 25 dbSNP
rs757989202 26 dbSNP
rs200113619 28 dbSNP
rs201894855 29 dbSNP
rs998281821 33 dbSNP
rs200498700 34 dbSNP
rs902163191 35 dbSNP
rs968310260 36 dbSNP
rs1473796743 39 dbSNP
rs199574664 40 dbSNP
rs1190869905 42 dbSNP
rs201515360 47 dbSNP
rs200990645 49 dbSNP
rs199547755 52 dbSNP
rs201128672 53 dbSNP
rs766386061 55 dbSNP
rs1438639682 57 dbSNP
rs564405003 58 dbSNP
rs763039134 59 dbSNP
rs1480068116 62 dbSNP
rs780313409 64 dbSNP
rs200258519 66 dbSNP
rs201808148 68 dbSNP
rs1228424988 72 dbSNP
rs75494144 75 dbSNP
rs957128437 80 dbSNP
rs1357790203 83 dbSNP
rs773381413 86 dbSNP
rs4987257 87 dbSNP
rs200203767 90 dbSNP
rs1378169886 93 dbSNP
rs1478953548 97 dbSNP
rs998246340 103 dbSNP
rs5753 105 dbSNP
rs937852807 113 dbSNP
rs202203460 116 dbSNP
rs1018242759 120 dbSNP
rs950124604 121 dbSNP
rs1348296561 122 dbSNP
rs1403381310 127 dbSNP
rs572317773 130 dbSNP
rs918606550 132 dbSNP
rs1349550332 133 dbSNP
rs1005484389 134 dbSNP
rs1324395135 138 dbSNP
rs776472527 140 dbSNP
rs1333355747 143 dbSNP
rs1417391424 146 dbSNP
rs1231658775 147 dbSNP
rs1168526014 149 dbSNP
rs201176852 151 dbSNP
rs887703239 152 dbSNP
rs1195533673 153 dbSNP
rs200202562 154 dbSNP
rs929236768 156 dbSNP
rs897676617 157 dbSNP
rs1245791407 160 dbSNP
rs13306046 164 dbSNP
rs1452838768 173 dbSNP
rs1270258546 174 dbSNP
rs939097479 176 dbSNP
rs1197827846 177 dbSNP
rs962793216 178 dbSNP
rs1198625496 183 dbSNP
rs746201652 184 dbSNP
rs35925773 186 dbSNP
rs980437631 190 dbSNP
rs11666103 196 dbSNP
rs954217840 202 dbSNP
rs998459585 203 dbSNP
rs1362145135 209 dbSNP
rs35551413 209 dbSNP
rs1393243524 210 dbSNP
rs1385606240 213 dbSNP
rs1323546666 215 dbSNP
rs1341674040 219 dbSNP
rs201759010 227 dbSNP
rs967340603 241 dbSNP
rs4987258 242 dbSNP
rs914907086 243 dbSNP
rs1438676031 250 dbSNP
rs1054800005 254 dbSNP
rs1358277330 259 dbSNP
rs1002471039 269 dbSNP
rs1266639196 271 dbSNP
rs1209951986 274 dbSNP
rs5754 275 dbSNP
rs956956539 276 dbSNP
rs8100569 282 dbSNP
rs1260355818 283 dbSNP
rs200784751 284 dbSNP
rs570239890 291 dbSNP
rs929259588 298 dbSNP
rs1369823260 303 dbSNP
rs1349259082 310 dbSNP
rs1037045629 311 dbSNP
rs919139445 311 dbSNP
rs528449012 312 dbSNP
rs8113664 314 dbSNP
rs183433108 315 dbSNP
rs1336037915 318 dbSNP
rs1293027084 322 dbSNP
rs1339863630 325 dbSNP
rs985547760 328 dbSNP
rs1377671248 330 dbSNP
rs964114717 331 dbSNP
rs1338897733 332 dbSNP
rs200453213 337 dbSNP
rs1018273851 343 dbSNP
rs5755 346 dbSNP
rs1160426518 352 dbSNP
rs1290699790 353 dbSNP
rs199616461 365 dbSNP
rs1470621473 366 dbSNP
rs1368076333 372 dbSNP
rs1186104172 374 dbSNP
rs1474070408 378 dbSNP
rs201218209 384 dbSNP
rs551836461 385 dbSNP
rs922811794 387 dbSNP
rs200628178 394 dbSNP
rs888478281 395 dbSNP
rs529655857 399 dbSNP
rs1187308860 402 dbSNP
rs966940795 403 dbSNP
rs1422079386 416 dbSNP
rs1157447688 418 dbSNP
rs1360446837 420 dbSNP
rs1466654872 429 dbSNP
rs570348088 430 dbSNP
rs868855083 432 dbSNP
rs1377287929 435 dbSNP
rs757724480 436 dbSNP
rs1206421734 437 dbSNP
rs1350799221 438 dbSNP
rs1272090181 439 dbSNP
rs148113390 440 dbSNP
rs1238397306 441 dbSNP
rs1442009927 444 dbSNP
rs5756 448 dbSNP
rs1294359895 449 dbSNP
rs1434213630 450 dbSNP
rs1178364446 452 dbSNP
rs375176055 453 dbSNP
rs1357434336 461 dbSNP
rs1465744306 464 dbSNP
rs957683500 469 dbSNP
rs1430625572 472 dbSNP
rs1402723051 474 dbSNP
rs1025625786 480 dbSNP
rs993851267 481 dbSNP
rs897713781 489 dbSNP
rs1401308861 491 dbSNP
rs1001974466 492 dbSNP
rs753206493 495 dbSNP
rs767821142 508 dbSNP
rs1393852267 523 dbSNP
rs959407018 535 dbSNP
rs1258351948 545 dbSNP
rs906252928 547 dbSNP
rs564621931 549 dbSNP
rs1463277989 550 dbSNP
rs1419751162 555 dbSNP
rs1232627694 557 dbSNP
rs1489096225 559 dbSNP
rs148977445 562 dbSNP
rs1280606414 565 dbSNP
rs1370255170 567 dbSNP
rs1003340519 572 dbSNP
rs1222093256 573 dbSNP
rs993705916 575 dbSNP
rs1367275540 577 dbSNP
rs1033773513 579 dbSNP
rs1000841564 582 dbSNP
rs968095830 584 dbSNP
rs1275671968 588 dbSNP
rs1044873335 592 dbSNP
rs777941632 593 dbSNP
rs1376405243 607 dbSNP
rs1330732721 608 dbSNP
rs200360639 609 dbSNP
rs1353633241 610 dbSNP
rs1491231536 610 dbSNP
rs202108063 610 dbSNP
rs34885751 610 dbSNP
rs537617338 610 dbSNP
rs543155102 610 dbSNP
rs758271809 610 dbSNP
rs1319596952 611 dbSNP
rs1400975956 613 dbSNP
rs897782202 614 dbSNP
rs1172668516 616 dbSNP
rs746898802 617 dbSNP
rs1424123462 618 dbSNP
rs1191478223 620 dbSNP
rs1471970882 621 dbSNP
rs1249226539 622 dbSNP
rs1478793761 623 dbSNP
rs1490322885 625 dbSNP
rs1235872416 629 dbSNP
rs1279278557 630 dbSNP
rs1037621723 633 dbSNP
rs1457783819 635 dbSNP
rs1260567480 636 dbSNP
rs1202260983 644 dbSNP
rs1312051243 646 dbSNP
rs1279763149 647 dbSNP
rs1221199183 650 dbSNP
rs5757 652 dbSNP
rs8113293 653 dbSNP
rs5758 654 dbSNP
rs946449591 659 dbSNP
rs1379132057 660 dbSNP
rs1333288393 664 dbSNP
rs1464478983 665 dbSNP
rs1358412914 670 dbSNP
rs1176481919 671 dbSNP
rs1415922046 672 dbSNP
rs1378123455 673 dbSNP
rs914913249 676 dbSNP
rs1439780244 677 dbSNP
rs1288108733 679 dbSNP
rs34486470 680 dbSNP
rs1217899871 681 dbSNP
rs376692879 681 dbSNP
rs13306048 683 dbSNP
rs1483194083 684 dbSNP
rs1238449552 687 dbSNP
rs932771833 693 dbSNP
rs756949674 694 dbSNP
rs1409071311 697 dbSNP
rs201136751 700 dbSNP
rs5759 701 dbSNP
rs964146372 704 dbSNP
rs1312995095 712 dbSNP
rs201880077 715 dbSNP
rs201078260 716 dbSNP
rs984193664 718 dbSNP
rs199908583 719 dbSNP
rs201500886 720 dbSNP
rs200731530 726 dbSNP
rs1449972102 727 dbSNP
rs1358320121 728 dbSNP
rs1282790411 731 dbSNP
rs1157749427 735 dbSNP
rs1382414043 735 dbSNP
rs191226440 736 dbSNP
rs1312179062 738 dbSNP
rs1026079356 740 dbSNP
rs976976584 743 dbSNP
rs994159542 745 dbSNP
rs201478687 747 dbSNP
rs1415183479 748 dbSNP
rs1184045633 749 dbSNP
rs200789014 751 dbSNP
rs989682634 752 dbSNP
rs553835608 754 dbSNP
rs1443851430 755 dbSNP
rs533698062 758 dbSNP
rs1263862131 759 dbSNP
rs199702743 760 dbSNP
rs201558078 777 dbSNP
rs200222934 782 dbSNP
rs199664662 786 dbSNP
rs574465378 787 dbSNP
rs201445336 790 dbSNP
rs1468493617 799 dbSNP
rs1235052627 801 dbSNP
rs776724393 804 dbSNP
rs1297328068 809 dbSNP
rs1033351803 814 dbSNP
rs1400274289 817 dbSNP
rs1362104877 818 dbSNP
rs980820130 820 dbSNP
rs200445019 823 dbSNP
rs201974658 824 dbSNP
rs760411830 827 dbSNP
rs1275528297 828 dbSNP
rs1335816484 829 dbSNP
rs1347289391 831 dbSNP
rs1217545425 832 dbSNP
rs1456982695 837 dbSNP
rs200663598 839 dbSNP
rs1011098919 841 dbSNP
rs10425128 842 dbSNP
rs1458364532 846 dbSNP
rs201087249 846 dbSNP
rs1423414518 848 dbSNP
rs1052547676 849 dbSNP
rs1478978514 853 dbSNP
rs200342215 854 dbSNP
rs4987261 860 dbSNP
rs922863748 860 dbSNP
rs202208040 861 dbSNP
rs201193721 863 dbSNP
rs537821952 865 dbSNP
rs1215534572 866 dbSNP
rs1173588681 869 dbSNP
rs199953331 870 dbSNP
rs1277445852 871 dbSNP
rs1219036849 873 dbSNP
rs1461501223 878 dbSNP
rs201792599 880 dbSNP
rs373550669 881 dbSNP
rs1385873418 883 dbSNP
rs1390902051 888 dbSNP
rs1391166047 890 dbSNP
rs748909775 892 dbSNP
rs1294751125 893 dbSNP
rs1006147235 898 dbSNP
rs532037213 898 dbSNP
rs116937991 902 dbSNP
rs1318912315 911 dbSNP
rs796297811 913 dbSNP
rs1306464321 914 dbSNP
rs932631564 922 dbSNP
rs200149996 935 dbSNP
rs35094768 942 dbSNP
rs1041523816 952 dbSNP
rs996979073 961 dbSNP
rs200698678 964 dbSNP
rs945582250 965 dbSNP
rs199916123 966 dbSNP
rs1374647806 968 dbSNP
rs1035692250 972 dbSNP
rs202037386 974 dbSNP
rs969278792 975 dbSNP
rs186315054 979 dbSNP
rs200899823 988 dbSNP
rs199552989 997 dbSNP
rs1023484752 1001 dbSNP
rs1010714321 1014 dbSNP
rs1359224661 1016 dbSNP
rs201349910 1017 dbSNP
rs547965346 1022 dbSNP
rs200606661 1024 dbSNP
rs970799585 1025 dbSNP
rs199700698 1028 dbSNP
rs1326040253 1030 dbSNP
rs1226481843 1031 dbSNP
rs999674089 1033 dbSNP
rs201542011 1044 dbSNP
rs1398563656 1046 dbSNP
rs1409658936 1048 dbSNP
rs1358389055 1058 dbSNP
rs200224190 1070 dbSNP
rs546720987 1077 dbSNP
rs202052056 1094 dbSNP
rs1182483697 1096 dbSNP
rs201694481 1097 dbSNP
rs1488370797 1100 dbSNP
rs1218128034 1110 dbSNP
rs200385343 1111 dbSNP
rs201686862 1113 dbSNP
rs200768620 1122 dbSNP
rs199982345 1136 dbSNP
rs1255848680 1142 dbSNP
rs1049042624 1143 dbSNP
rs202209416 1147 dbSNP
rs749474332 1151 dbSNP
rs1016124541 1159 dbSNP
rs548204900 1166 dbSNP
rs1443342690 1167 dbSNP
rs1163569569 1172 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903829
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / CTLTD_shCTL_a
Location of target site NM_001060 | 3UTR | GCCUCAGCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903831
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / 124TD_shELAVL3_a
Location of target site NM_001060 | 3UTR | CCUCAGCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903832
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / 124TD_shELAVL3_b
Location of target site NM_001060 | 3UTR | GCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001060 | 3UTR | GCCUCAGCCUCCCAAAGUGCUGGGAUCACAGGCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001060 | 3UTR | CCUCAGCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001060 | 3UTR | CCUCAGCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001060 | 3UTR | GCCUCAGCCUCCCAAAGUGCUGGGAUCACAGGCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001060 | 3UTR | CAGCCUCAGCCUCCCAAAGUGCUGGGAUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_001060 | 3UTR | CUCAGCCUCCCAAAGUGCUGGGAUCACAGGCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000375190.4 | 3UTR | CCUCCCAAAGUGCUGGGAUCACAGGCAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
390 hsa-miR-4419b Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061343 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT072743 GLCE glucuronic acid epimerase 2 2
MIRT180549 TXNIP thioredoxin interacting protein 2 2
MIRT186147 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT271044 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT334761 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 6
MIRT443279 TSPAN15 tetraspanin 15 2 2
MIRT447047 ZNF439 zinc finger protein 439 2 2
MIRT447351 KIF6 kinesin family member 6 2 2
MIRT448925 CKS1B CDC28 protein kinase regulatory subunit 1B 2 2
MIRT452899 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453087 SUMF2 sulfatase modifying factor 2 2 2
MIRT454071 SLC35E3 solute carrier family 35 member E3 2 2
MIRT456216 LIX1L limb and CNS expressed 1 like 2 6
MIRT456951 LRP10 LDL receptor related protein 10 2 2
MIRT458025 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT459999 RFT1 RFT1 homolog 2 2
MIRT460046 CDCP1 CUB domain containing protein 1 2 2
MIRT460982 STK17B serine/threonine kinase 17b 2 2
MIRT464405 URM1 ubiquitin related modifier 1 2 2
MIRT466256 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 2
MIRT466536 TBXA2R thromboxane A2 receptor 2 2
MIRT470922 PLD5 phospholipase D family member 5 2 8
MIRT472835 MTMR10 myotubularin related protein 10 2 6
MIRT473352 MEMO1 mediator of cell motility 1 2 2
MIRT475504 HSP90B1 heat shock protein 90 beta family member 1 2 2
MIRT478862 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT480898 BCL9L B-cell CLL/lymphoma 9 like 2 2
MIRT482686 NXN nucleoredoxin 2 4
MIRT484128 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT486172 TLE3 transducin like enhancer of split 3 2 4
MIRT486539 CLCN7 chloride voltage-gated channel 7 2 2
MIRT486588 ZNF619 zinc finger protein 619 2 2
MIRT495475 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT495536 TXNRD2 thioredoxin reductase 2 2 2
MIRT495566 UNC5C unc-5 netrin receptor C 2 2
MIRT495719 PADI1 peptidyl arginine deiminase 1 2 2
MIRT495890 CLOCK clock circadian regulator 2 2
MIRT495932 SLC7A5P2 solute carrier family 7 member 5 pseudogene 2 2 2
MIRT496026 ZBED3 zinc finger BED-type containing 3 2 2
MIRT496216 PAX6 paired box 6 2 2
MIRT496349 VAMP1 vesicle associated membrane protein 1 2 2
MIRT496354 PPY pancreatic polypeptide 2 2
MIRT496400 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT496416 PARVB parvin beta 2 2
MIRT496458 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 2 2
MIRT496519 GINS2 GINS complex subunit 2 2 2
MIRT496562 SLC39A9 solute carrier family 39 member 9 2 2
MIRT498605 KRT8 keratin 8 2 2
MIRT503434 SLC25A45 solute carrier family 25 member 45 2 6
MIRT503573 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT503847 ATP13A4 ATPase 13A4 2 4
MIRT504247 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2 4
MIRT505606 SLC35F1 solute carrier family 35 member F1 2 2
MIRT507749 CERS2 ceramide synthase 2 2 4
MIRT508411 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508508 RSRC1 arginine and serine rich coiled-coil 1 2 6
MIRT508944 AK4 adenylate kinase 4 2 4
MIRT509460 ZNF587 zinc finger protein 587 2 6
MIRT509862 ZNF641 zinc finger protein 641 2 4
MIRT511397 IKZF3 IKAROS family zinc finger 3 2 6
MIRT512517 BTBD19 BTB domain containing 19 2 2
MIRT513507 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 6
MIRT514155 TMEM145 transmembrane protein 145 2 4
MIRT514486 SLPI secretory leukocyte peptidase inhibitor 2 4
MIRT514521 SHISA9 shisa family member 9 2 2
MIRT514970 KLLN killin, p53-regulated DNA replication inhibitor 2 4
MIRT515030 IRAK4 interleukin 1 receptor associated kinase 4 2 6
MIRT515963 C9orf156 tRNA methyltransferase O 2 2
MIRT516092 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT517223 PRIM1 DNA primase subunit 1 2 4
MIRT517459 PEX26 peroxisomal biogenesis factor 26 2 4
MIRT517790 EFCAB11 EF-hand calcium binding domain 11 2 2
MIRT517979 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT519458 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT519599 ZNF805 zinc finger protein 805 2 2
MIRT520339 UBXN2A UBX domain protein 2A 2 2
MIRT521345 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT521571 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT523382 GSG2 histone H3 associated protein kinase 2 8
MIRT524106 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT524886 ARHGAP11A Rho GTPase activating protein 11A 2 4
MIRT528772 CD1D CD1d molecule 2 2
MIRT530665 TRIM56 tripartite motif containing 56 2 2
MIRT531107 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT531575 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT535173 PLEKHB2 pleckstrin homology domain containing B2 2 4
MIRT544168 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT550582 SLC2A5 solute carrier family 2 member 5 2 2
MIRT551039 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT551295 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551339 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT552092 SLFN12L schlafen family member 12 like 2 6
MIRT555403 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT557087 HOXB3 homeobox B3 2 2
MIRT559388 ATP11C ATPase phospholipid transporting 11C 2 2
MIRT560305 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT561028 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT562460 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT562982 PARK7 Parkinsonism associated deglycase 2 2
MIRT563548 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT564412 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT569437 PCGF3 polycomb group ring finger 3 2 2
MIRT572097 EXOC8 exocyst complex component 8 2 2
MIRT575571 Cd99 CD99 antigen 2 2
MIRT575789 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT576975 Lmtk2 lemur tyrosine kinase 2 2 2
MIRT610864 ARSA arylsulfatase A 2 2
MIRT614061 NTPCR nucleoside-triphosphatase, cancer-related 2 2
MIRT614141 THAP1 THAP domain containing 1 2 6
MIRT615235 BROX BRO1 domain and CAAX motif containing 2 2
MIRT617429 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT618882 MBL2 mannose binding lectin 2 2 2
MIRT618984 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619196 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620323 AQP6 aquaporin 6 2 2
MIRT621960 STX7 syntaxin 7 2 2
MIRT622057 SSBP2 single stranded DNA binding protein 2 2 2
MIRT624930 FBXW2 F-box and WD repeat domain containing 2 2 2
MIRT624986 ZNF665 zinc finger protein 665 2 4
MIRT625463 ZNF681 zinc finger protein 681 2 4
MIRT625497 SMAD9 SMAD family member 9 2 2
MIRT625599 KLHL23 kelch like family member 23 2 2
MIRT625668 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT625888 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT626161 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT626238 ZNF749 zinc finger protein 749 2 2
MIRT626631 SLC30A6 solute carrier family 30 member 6 2 2
MIRT626994 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627898 OLFML2A olfactomedin like 2A 2 2
MIRT627988 NDRG3 NDRG family member 3 2 2
MIRT628324 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT628549 ZNF701 zinc finger protein 701 2 2
MIRT629464 WIZ widely interspaced zinc finger motifs 2 2
MIRT630527 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT631487 KLHL21 kelch like family member 21 2 2
MIRT631957 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632178 CCL22 C-C motif chemokine ligand 22 2 2
MIRT632282 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT632321 TMEM185B transmembrane protein 185B 2 2
MIRT632853 IGF1 insulin like growth factor 1 2 2
MIRT632862 HSPA2 heat shock protein family A (Hsp70) member 2 2 2
MIRT633322 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT633398 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT633930 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT634785 CBFA2T2 CBFA2/RUNX1 translocation partner 2 2 2
MIRT634851 ABCF1 ATP binding cassette subfamily F member 1 2 2
MIRT636370 OGFRL1 opioid growth factor receptor like 1 2 2
MIRT637219 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT637690 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D 2 2
MIRT639196 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT639599 CD3EAP CD3e molecule associated protein 2 2
MIRT639681 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT640669 ARSK arylsulfatase family member K 2 2
MIRT642377 ZNF581 zinc finger protein 581 2 2
MIRT642403 ZNF556 zinc finger protein 556 2 2
MIRT645079 UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII 2 2
MIRT646475 ZNF669 zinc finger protein 669 2 2
MIRT647325 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT647490 ZNF639 zinc finger protein 639 2 2
MIRT647989 PDE12 phosphodiesterase 12 2 2
MIRT648196 CENPN centromere protein N 2 2
MIRT649006 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT650457 ZNF141 zinc finger protein 141 2 2
MIRT650533 CCDC77 coiled-coil domain containing 77 2 2
MIRT650999 ZNF770 zinc finger protein 770 2 2
MIRT653832 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 4
MIRT655734 NRXN3 neurexin 3 2 2
MIRT657577 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT658610 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT658633 ENAH ENAH, actin regulator 2 2
MIRT659820 CASP16 caspase 16, pseudogene 2 2
MIRT661142 ZNF43 zinc finger protein 43 2 2
MIRT661201 MPPE1 metallophosphoesterase 1 2 2
MIRT661436 MANSC1 MANSC domain containing 1 2 2
MIRT661498 CHMP1B charged multivesicular body protein 1B 2 2
MIRT661682 ZNF623 zinc finger protein 623 2 2
MIRT661796 NLRC3 NLR family CARD domain containing 3 2 2
MIRT661808 NUP85 nucleoporin 85 2 2
MIRT661861 ZNF766 zinc finger protein 766 2 2
MIRT661889 EXOSC6 exosome component 6 2 2
MIRT662291 SLC29A4 solute carrier family 29 member 4 2 2
MIRT662515 ANGPT4 angiopoietin 4 2 2
MIRT662682 LRRC47 leucine rich repeat containing 47 2 2
MIRT662716 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT662834 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT662890 PCDHA6 protocadherin alpha 6 2 2
MIRT663134 ULBP3 UL16 binding protein 3 2 2
MIRT663710 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663869 MUC20 mucin 20, cell surface associated 2 2
MIRT664267 NMUR1 neuromedin U receptor 1 2 2
MIRT664510 POLR3K RNA polymerase III subunit K 2 2
MIRT664659 TRIM65 tripartite motif containing 65 2 2
MIRT664849 HUS1 HUS1 checkpoint clamp component 2 2
MIRT664944 CARD6 caspase recruitment domain family member 6 2 4
MIRT665348 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT665514 UTP15 UTP15, small subunit processome component 2 2
MIRT665648 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT665668 TRAF1 TNF receptor associated factor 1 2 2
MIRT665692 TNPO3 transportin 3 2 2
MIRT665741 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT665850 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT665940 TBC1D19 TBC1 domain family member 19 2 4
MIRT666005 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT666172 SNX27 sorting nexin family member 27 2 4
MIRT666373 SHOX short stature homeobox 2 2
MIRT667004 PDPN podoplanin 2 4
MIRT667185 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667603 LIPC lipase C, hepatic type 2 2
MIRT667828 IRGQ immunity related GTPase Q 2 2
MIRT667862 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668296 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 4
MIRT668463 FAM208A family with sequence similarity 208 member A 2 2
MIRT668580 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT669012 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT669103 CDK19 cyclin dependent kinase 19 2 2
MIRT670073 ZNF783 zinc finger family member 783 2 2
MIRT670326 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT670756 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670964 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT670985 MED17 mediator complex subunit 17 2 2
MIRT671195 ZNF891 zinc finger protein 891 2 2
MIRT672423 SLC10A6 solute carrier family 10 member 6 2 2
MIRT672495 YIPF4 Yip1 domain family member 4 2 2
MIRT672537 MGAM maltase-glucoamylase 2 2
MIRT672749 ZNF585B zinc finger protein 585B 2 4
MIRT673390 ZNF124 zinc finger protein 124 2 2
MIRT673452 ZNF583 zinc finger protein 583 2 2
MIRT673917 DCTN6 dynactin subunit 6 2 2
MIRT673952 ZNF500 zinc finger protein 500 2 2
MIRT674102 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674167 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674206 FUT2 fucosyltransferase 2 2 2
MIRT674452 PURB purine rich element binding protein B 2 4
MIRT674687 PLCE1 phospholipase C epsilon 1 2 2
MIRT674701 TMEM59 transmembrane protein 59 2 2
MIRT674800 NPR1 natriuretic peptide receptor 1 2 4
MIRT675247 MAK male germ cell associated kinase 2 2
MIRT676012 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676374 APTX aprataxin 2 2
MIRT676834 TNFSF15 TNF superfamily member 15 2 2
MIRT678193 CRCP CGRP receptor component 2 2
MIRT678293 PTRH2 peptidyl-tRNA hydrolase 2 2 2
MIRT679532 RAB36 RAB36, member RAS oncogene family 2 2
MIRT679669 RABAC1 Rab acceptor 1 2 2
MIRT679850 GPR75 G protein-coupled receptor 75 2 2
MIRT680533 PRIM2 DNA primase subunit 2 2 2
MIRT680563 ZNF584 zinc finger protein 584 2 2
MIRT680577 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT680849 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT680888 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT680940 EVC EvC ciliary complex subunit 1 2 2
MIRT680964 SLC15A1 solute carrier family 15 member 1 2 4
MIRT681017 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681065 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT681209 ZNF638 zinc finger protein 638 2 2
MIRT681291 RFC2 replication factor C subunit 2 2 2
MIRT681366 BRI3BP BRI3 binding protein 2 2
MIRT681517 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681549 ZNF738 zinc finger protein 738 2 2
MIRT681574 ABHD15 abhydrolase domain containing 15 2 2
MIRT681597 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT681806 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681912 SLC11A2 solute carrier family 11 member 2 2 2
MIRT681953 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682037 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT682111 ITGA3 integrin subunit alpha 3 2 4
MIRT682190 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682247 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682394 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682554 EXOSC2 exosome component 2 2 2
MIRT682665 CASP8 caspase 8 2 2
MIRT683283 ZNF99 zinc finger protein 99 2 2
MIRT683359 SCARF1 scavenger receptor class F member 1 2 2
MIRT683453 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT683596 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT683661 ZNF695 zinc finger protein 695 2 2
MIRT683770 CPE carboxypeptidase E 2 2
MIRT683807 NOTO notochord homeobox 2 2
MIRT684462 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684525 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT684985 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685012 CXorf56 chromosome X open reading frame 56 2 2
MIRT685072 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685115 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685477 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT685831 SLC27A1 solute carrier family 27 member 1 2 2
MIRT686032 UMPS uridine monophosphate synthetase 2 2
MIRT686559 TPM3 tropomyosin 3 2 2
MIRT687287 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT687309 OTUD7B OTU deubiquitinase 7B 2 2
MIRT688085 GLUL glutamate-ammonia ligase 2 2
MIRT688168 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688584 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT688601 CYCS cytochrome c, somatic 2 2
MIRT688921 C11orf84 chromosome 11 open reading frame 84 2 2
MIRT689285 C5AR2 complement component 5a receptor 2 2 2
MIRT689622 AKAP6 A-kinase anchoring protein 6 2 2
MIRT690051 C6orf141 chromosome 6 open reading frame 141 2 2
MIRT690224 C5orf45 MRN complex interacting protein 2 2
MIRT690272 CAMLG calcium modulating ligand 2 2
MIRT690331 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT690480 ZNF33A zinc finger protein 33A 2 2
MIRT690526 ZNF566 zinc finger protein 566 2 2
MIRT690581 MICA MHC class I polypeptide-related sequence A 2 2
MIRT690675 RPF2 ribosome production factor 2 homolog 2 2
MIRT690790 ZNF589 zinc finger protein 589 2 2
MIRT690873 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691142 HJURP Holliday junction recognition protein 2 2
MIRT691158 APOL6 apolipoprotein L6 2 2
MIRT691288 CENPM centromere protein M 2 2
MIRT691435 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT691749 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT691833 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT691885 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT691947 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT692047 PAK1IP1 PAK1 interacting protein 1 2 2
MIRT692668 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT692767 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT692859 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT693122 SCNM1 sodium channel modifier 1 2 2
MIRT693514 MOB3A MOB kinase activator 3A 2 2
MIRT693648 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT693688 MXRA7 matrix remodeling associated 7 2 2
MIRT694078 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT694163 SLC36A2 solute carrier family 36 member 2 2 2
MIRT694262 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT694506 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT694556 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694639 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT694710 CD300LG CD300 molecule like family member g 2 2
MIRT694753 LLGL1 LLGL1, scribble cell polarity complex component 2 2
MIRT694896 ZNF417 zinc finger protein 417 2 2
MIRT695158 BTD biotinidase 2 2
MIRT695275 CD209 CD209 molecule 2 2
MIRT695434 TCF23 transcription factor 23 2 2
MIRT695817 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT696008 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT696345 SLC35D2 solute carrier family 35 member D2 2 2
MIRT696368 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT696533 C3 complement C3 2 2
MIRT696779 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT697075 PSMC4 proteasome 26S subunit, ATPase 4 2 2
MIRT697498 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT697630 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT697931 TXNDC16 thioredoxin domain containing 16 2 2
MIRT697966 TSPYL1 TSPY like 1 2 2
MIRT698237 TMEM216 transmembrane protein 216 2 2
MIRT698643 TES testin LIM domain protein 2 2
MIRT698661 TERF2 telomeric repeat binding factor 2 2 2
MIRT698974 SPAST spastin 2 2
MIRT699047 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699193 SLX4IP SLX4 interacting protein 2 2
MIRT699586 SIKE1 suppressor of IKBKE 1 2 2
MIRT699759 SEPHS1 selenophosphate synthetase 1 2 2
MIRT700350 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT700402 RAB13 RAB13, member RAS oncogene family 2 2
MIRT700418 QDPR quinoid dihydropteridine reductase 2 2
MIRT700546 PTBP2 polypyrimidine tract binding protein 2 2 2
MIRT700774 PLA2G4A phospholipase A2 group IVA 2 2
MIRT700875 PER2 period circadian clock 2 2 2
MIRT700952 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT701077 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT701172 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT701479 NEK9 NIMA related kinase 9 2 2
MIRT701661 MYH9 myosin heavy chain 9 2 2
MIRT701779 MSL2 MSL complex subunit 2 2 2
MIRT702137 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT702494 KIAA1328 KIAA1328 2 2
MIRT703058 GTPBP10 GTP binding protein 10 2 2
MIRT703224 GOLGA3 golgin A3 2 2
MIRT703620 FBXO45 F-box protein 45 2 2
MIRT703657 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT703765 FAM118A family with sequence similarity 118 member A 2 2
MIRT703832 EVI5 ecotropic viral integration site 5 2 2
MIRT703862 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT704664 CLCC1 chloride channel CLIC like 1 2 2
MIRT704812 CDC73 cell division cycle 73 2 2
MIRT705608 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT705625 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT705682 ANKRD40 ankyrin repeat domain 40 2 2
MIRT705813 AKNA AT-hook transcription factor 2 2
MIRT706238 SYT15 synaptotagmin 15 2 2
MIRT706567 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT709657 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710609 ZNF555 zinc finger protein 555 2 2
MIRT711717 IREB2 iron responsive element binding protein 2 2 2
MIRT714122 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT715204 FKTN fukutin 2 2
MIRT718260 ZDHHC8 zinc finger DHHC-type containing 8 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4419b Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Cisplatin + Decitabine resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-4419b Androstenedione+Anastrozole sensitive cell line (MCF-7)

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