miRTarBase - #MIRT468456


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pre-miRNA Information
pre-miRNA hsa-mir-3152   
Genomic Coordinates chr9: 18573306 - 18573379
Description Homo sapiens miR-3152 stem-loop
Comment Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3152-5p
Sequence 11| AUUGCCUCUGUUCUAACACAAG |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1019691326 2 dbSNP
rs1282676806 8 dbSNP
rs762305650 11 dbSNP
rs1364318615 12 dbSNP
rs556364307 18 dbSNP
rs1002755159 19 dbSNP
rs1238555909 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SET   
Synonyms 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Description SET nuclear proto-oncogene
Transcript NM_001122821   
Other Transcripts NM_003011   
Expression
Putative miRNA Targets on SET
3'UTR of SET
(miRNA target sites are highlighted)		 
>SET|NM_001122821|3'UTR
   1 ATAGAACACTGATGGATTCCAACCTTCCTTTTTTTAAATTTTCTCCAGTCCCTGGGAGCAAGTTGCAGTCTTTTTTTTTT
  81 TTTTTTTTTTTTTTCCCTCTTGTGCTCAGTCGCCCTGTTCTTGAGGTCTCTTTTCTCTACTCCATGGTTCTCAATTTATT
 161 TGGGGGGAAATACCTTGAGCAGAATACAATGGGAAAAGAGTCTCTACCCCTTTCTGTTCGAAGTTCATTTTTATCCCTTC
 241 CTGTCTGAACAAAAACTGTATGGAATCAACACCACCGAGCTCTGTGGGAAAAAAGAAAAACCTGCTCCCTTCGCTCTGCT
 321 GGAAGCTGGAGGGTGCTAGGCCCCTGTGTAGTAGTGCATAGAATTCTAGCTTTTTTCCTCCTTTCTCTGTATATTGGGCT
 401 CAGAGAGTACACTGTGTCTCTATGTGAATATGGACAGTTAGCATTTACCAACATGTATCTGTCTACTTTCTCTTGTTTAA
 481 AAAAAGAAAAAAAAACTTAAAAAAATGGGGTTATAGAAGGTCAGCAAAGGGTGGGTTTGAGATGTTTGGGTGGGTTAAGT
 561 GGGCATTTTGACAACATGGCTTCTCCTTTGGCATGTTTAATTGTGATATTTGACAGACATCCTTGCAGTTTAAGATGACA
 641 CTTTTAAAATAAATTCTCTCCTAATGATGACTTGAGCCCTGCCACTCAATGGGAGAATCAGCAGAACCTGTAGGATCTTA
 721 TTTGGAATTGACATTCTCTATTGTAATTTTGTTCCTGTTTATTTTTAAATTTTCTTTTTGTTTCACTGGAAAGGAAAGAT
 801 GATGCTCAGTTTTAAACGTTAAAAGTGTACAAGTTGCTTTGTTACAATAAAACTAAATGTGTACACAAAGGATTTGATGC
 881 TTTTCTCTCAGCATAGGTATGCTTACTATGACCTTCCAAGTTTGACTTGTATAACATCACTGTCAAACTTTGTCACCCTA
 961 ACTTCGTATTTTTTGATACGCACTTTGCAGGATGACCTCAGGGCTATGTGGATTGAGTAATGGGATTTGAATCAATGTAT
1041 TAATATCTCCATAGCTGGGAAACGTGGGTTCAATTTGCCATTGGTTTCTGAAAGTATTCACATCATTTGGGATACCAGAT
1121 AGCTCAATACTCTCTGAGTACATTGTGCCCTTGATTTTTATCTCCAAGTGGCAGTTTTTAAAATTGGCCTTTTACCTGGA
1201 TATAAATTAATTGTGCCTGCCACCACCATCCAACAGACCTGGTGCTCTAATGCCAAGTTATACACGGGACAGTTGCTGGC
1281 ATGTCTTCATTGGCTATATAAAATGTGGCCAAGAAGATAGGCTCTCAGTAAGAAGTCTGATGGTGAGCAGTAACTGTCCC
1361 TGCTTTCTGGTATAAAGCTCTCAAATGTGACCATGTGAATCTGGGTGGGATAATGGACTCAGCTCTGTCTGCTCAATGCC
1441 ATTGTGCAGAGAAGCACCCTAATGCATAAGCTTTTTAATGCTGTAAAATATAGTCGCTGAAATTAAATGCCACTTTTTCA
1521 GAGGTGAATTAATGGACAGTCTGGTGAACTTCAAAAGCTTTTTGATGTATAAAACTTGATAAATGGAACTATTCCATCAA
1601 TAGGCAAAAGTGTAACAACCTATCTAGATGGATAGTATGTAATTTCTGCACAGGTCTCTGTTTAGTAAATACATCACTGT
1681 ATACCGATCAGGAATCTTGCTCCAATAAAGGAACATAAAGATTTTTTTTGGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaacacaaucuugucUCCGUUa 5'
                         |||||| 
Target 5' aactattccatcaatAGGCAAa 3'
 1587 - 1608 120.00 -5.50
2 
miRNA  3' gaacacaaucuuGUCUCCGUUa 5'
                      ||||||::| 
Target 5' atgccactttttCAGAGGTGAa 3'
 1507 - 1528 118.00 -8.62
3 
miRNA  3' gaACACAAUCUU--GUCUCCguua 5'
            | || |:|||  ::||||    
Target 5' gcTCTGCTGGAAGCTGGAGGgtgc 3'
 313 - 336 102.00 -8.36
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31578305 33 COSMIC
COSN30498273 36 COSMIC
COSN8892649 44 COSMIC
COSN15661098 51 COSMIC
COSN30455582 53 COSMIC
COSN8520012 95 COSMIC
COSN31513137 96 COSMIC
COSN20121209 98 COSMIC
COSN30499218 102 COSMIC
COSN16131139 178 COSMIC
COSN26669927 211 COSMIC
COSN31521271 220 COSMIC
COSN26560736 224 COSMIC
COSN31516803 278 COSMIC
COSN26578376 305 COSMIC
COSN24302881 310 COSMIC
COSN26668234 310 COSMIC
COSN26578080 313 COSMIC
COSN17898237 330 COSMIC
COSN7557326 453 COSMIC
COSN26059481 464 COSMIC
COSN21483967 500 COSMIC
COSN31555527 509 COSMIC
COSN7557327 534 COSMIC
COSN28724429 599 COSMIC
COSN22210264 613 COSMIC
COSN16015314 735 COSMIC
COSN26644690 750 COSMIC
COSN26640872 756 COSMIC
COSN26641455 777 COSMIC
COSN16130788 785 COSMIC
COSN26581837 818 COSMIC
COSN26559503 819 COSMIC
COSN22300118 853 COSMIC
COSN26466373 871 COSMIC
COSN9700851 872 COSMIC
COSN28791364 877 COSMIC
COSN29467514 885 COSMIC
COSN26676293 894 COSMIC
COSN29467515 911 COSMIC
COSN9700852 931 COSMIC
COSN16553854 945 COSMIC
COSN17656509 950 COSMIC
COSN31485377 966 COSMIC
COSN31551260 967 COSMIC
COSN26586433 988 COSMIC
COSN20872253 1003 COSMIC
COSN30164488 1034 COSMIC
COSN31487229 1078 COSMIC
COSN31536271 1114 COSMIC
COSN31863753 1133 COSMIC
COSN20092022 1271 COSMIC
COSN28158667 1479 COSMIC
COSN31570738 1558 COSMIC
COSN30176291 1565 COSMIC
COSN28778171 1618 COSMIC
COSN22754611 1628 COSMIC
COSN30164596 1676 COSMIC
COSN31589569 1721 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs201084109 3 dbSNP
rs778935425 4 dbSNP
rs1205431007 9 dbSNP
rs748401461 13 dbSNP
rs770664474 17 dbSNP
rs1475645856 25 dbSNP
rs758424822 27 dbSNP
rs374784143 28 dbSNP
rs780995494 29 dbSNP
rs747129594 36 dbSNP
rs1430726635 37 dbSNP
rs1262975246 39 dbSNP
rs771336964 44 dbSNP
rs1209777945 46 dbSNP
rs777251642 47 dbSNP
rs371016083 48 dbSNP
rs749528164 50 dbSNP
rs1430599459 51 dbSNP
rs997161203 58 dbSNP
rs973219901 69 dbSNP
rs1316915131 70 dbSNP
rs1029855628 71 dbSNP
rs1168816855 71 dbSNP
rs1193695796 71 dbSNP
rs1198724285 71 dbSNP
rs1275970975 71 dbSNP
rs1327972565 71 dbSNP
rs1374028635 71 dbSNP
rs1399822721 71 dbSNP
rs1431909683 71 dbSNP
rs1456939899 71 dbSNP
rs1463793893 71 dbSNP
rs1491156473 71 dbSNP
rs35778650 71 dbSNP
rs397894105 71 dbSNP
rs919062743 71 dbSNP
rs1255688113 72 dbSNP
rs1491477121 72 dbSNP
rs950630885 73 dbSNP
rs1365658306 74 dbSNP
rs1339772056 76 dbSNP
rs1255173741 88 dbSNP
rs748534458 91 dbSNP
rs77610267 92 dbSNP
rs982011545 94 dbSNP
rs201363886 95 dbSNP
rs770267607 95 dbSNP
rs1372252997 96 dbSNP
rs1386986190 97 dbSNP
rs1217210497 98 dbSNP
rs1271802744 100 dbSNP
rs567892521 102 dbSNP
rs1307721223 103 dbSNP
rs10988092 104 dbSNP
rs1397526802 107 dbSNP
rs1172351102 109 dbSNP
rs1205933944 112 dbSNP
rs1263152447 113 dbSNP
rs1438497781 114 dbSNP
rs1235853308 118 dbSNP
rs1490062491 119 dbSNP
rs927963646 121 dbSNP
rs938018380 126 dbSNP
rs1055658783 127 dbSNP
rs1198509162 129 dbSNP
rs1349787202 131 dbSNP
rs1200016949 133 dbSNP
rs1239360402 134 dbSNP
rs1271016193 135 dbSNP
rs1353022147 138 dbSNP
rs1476688662 139 dbSNP
rs530638331 147 dbSNP
rs915308571 155 dbSNP
rs946917176 157 dbSNP
rs1333763088 159 dbSNP
rs1042548084 161 dbSNP
rs1377677779 162 dbSNP
rs1313978717 163 dbSNP
rs1419595802 164 dbSNP
rs1379054914 165 dbSNP
rs1419005821 167 dbSNP
rs1470257927 170 dbSNP
rs1367461161 174 dbSNP
rs1486500145 182 dbSNP
rs10988093 183 dbSNP
rs1487262829 186 dbSNP
rs570062884 187 dbSNP
rs1225474811 191 dbSNP
rs1351514856 194 dbSNP
rs867179125 196 dbSNP
rs1231723684 197 dbSNP
rs1357647288 200 dbSNP
rs902669014 208 dbSNP
rs998848110 210 dbSNP
rs1399845202 214 dbSNP
rs1051343142 215 dbSNP
rs1172898826 217 dbSNP
rs867662407 220 dbSNP
rs1320854210 224 dbSNP
rs890154601 228 dbSNP
rs1007207131 229 dbSNP
rs1161050654 230 dbSNP
rs1304231656 231 dbSNP
rs1347972972 237 dbSNP
rs1418179867 238 dbSNP
rs1192666372 239 dbSNP
rs1476722898 240 dbSNP
rs1428983355 246 dbSNP
rs1243722080 247 dbSNP
rs1269991917 254 dbSNP
rs1216441526 257 dbSNP
rs1447616993 261 dbSNP
rs1289204956 262 dbSNP
rs1211955821 270 dbSNP
rs573709807 277 dbSNP
rs1215957604 278 dbSNP
rs542731825 283 dbSNP
rs1358074932 286 dbSNP
rs1360327848 286 dbSNP
rs1017393152 295 dbSNP
rs1293800383 301 dbSNP
rs1323278667 302 dbSNP
rs1487277352 305 dbSNP
rs963136096 306 dbSNP
rs1215056452 309 dbSNP
rs994564225 311 dbSNP
rs1061240 313 dbSNP
rs796756794 317 dbSNP
rs1476295569 318 dbSNP
rs1477644946 320 dbSNP
rs950545924 327 dbSNP
rs78124756 330 dbSNP
rs1469881240 331 dbSNP
rs1273981965 337 dbSNP
rs1383641320 338 dbSNP
rs1444045975 339 dbSNP
rs1275513277 341 dbSNP
rs1215569539 342 dbSNP
rs1367496133 344 dbSNP
rs1164301268 345 dbSNP
rs1301893449 351 dbSNP
rs1367941106 354 dbSNP
rs1442398681 359 dbSNP
rs1371126476 360 dbSNP
rs10988094 362 dbSNP
rs1330224810 367 dbSNP
rs1439533927 371 dbSNP
rs1355967766 373 dbSNP
rs1399449819 378 dbSNP
rs1318322607 379 dbSNP
rs1346125662 381 dbSNP
rs1433386026 382 dbSNP
rs1334227643 386 dbSNP
rs1175453196 393 dbSNP
rs538977146 394 dbSNP
rs10988095 404 dbSNP
rs1253737526 405 dbSNP
rs10988096 406 dbSNP
rs982471822 408 dbSNP
rs927900859 412 dbSNP
rs1245985138 421 dbSNP
rs1311991628 421 dbSNP
rs1278756034 430 dbSNP
rs959661792 431 dbSNP
rs990769229 434 dbSNP
rs1307871998 435 dbSNP
rs1348010746 436 dbSNP
rs1223117649 444 dbSNP
rs1221634663 450 dbSNP
rs1284935456 453 dbSNP
rs1446943344 455 dbSNP
rs1448468430 456 dbSNP
rs1207794594 462 dbSNP
rs1314601198 462 dbSNP
rs1373416311 462 dbSNP
rs1241450180 463 dbSNP
rs1158454444 466 dbSNP
rs915215300 468 dbSNP
rs1410371041 474 dbSNP
rs946822358 476 dbSNP
rs1255814811 479 dbSNP
rs1483107326 479 dbSNP
rs1213529510 484 dbSNP
rs1042416605 487 dbSNP
rs10988097 487 dbSNP
rs1286012753 487 dbSNP
rs1318209903 487 dbSNP
rs139027346 494 dbSNP
rs1184498568 495 dbSNP
rs1353220371 496 dbSNP
rs1387156663 496 dbSNP
rs1294874510 499 dbSNP
rs762630044 499 dbSNP
rs1158473838 500 dbSNP
rs1409377152 502 dbSNP
rs1287065475 505 dbSNP
rs1402758932 506 dbSNP
rs924122091 507 dbSNP
rs1347073093 510 dbSNP
rs566109184 511 dbSNP
rs1452914801 512 dbSNP
rs1338346575 513 dbSNP
rs143324900 515 dbSNP
rs1416038260 517 dbSNP
rs1440868353 526 dbSNP
rs1280028549 528 dbSNP
rs1352756431 530 dbSNP
rs555332547 534 dbSNP
rs1221402478 535 dbSNP
rs934171127 544 dbSNP
rs60115664 548 dbSNP
rs1486537350 552 dbSNP
rs1204512593 561 dbSNP
rs1245253788 571 dbSNP
rs1332198527 572 dbSNP
rs1436100137 576 dbSNP
rs1193695962 581 dbSNP
rs1339623448 585 dbSNP
rs1051804828 586 dbSNP
rs890028392 587 dbSNP
rs1233894376 590 dbSNP
rs1461051872 596 dbSNP
rs1471448566 597 dbSNP
rs1167390923 600 dbSNP
rs942917197 604 dbSNP
rs1174992713 605 dbSNP
rs191018343 607 dbSNP
rs1470537467 613 dbSNP
rs1178089242 622 dbSNP
rs1466749946 623 dbSNP
rs1393920002 640 dbSNP
rs1408792723 643 dbSNP
rs1038737211 645 dbSNP
rs1249384668 650 dbSNP
rs1229413856 651 dbSNP
rs898793740 661 dbSNP
rs1300510094 664 dbSNP
rs369703905 664 dbSNP
rs1337077992 669 dbSNP
rs1368898365 674 dbSNP
rs994596688 678 dbSNP
rs1403021566 680 dbSNP
rs1282603570 683 dbSNP
rs1345887584 685 dbSNP
rs1225140858 690 dbSNP
rs1463908829 703 dbSNP
rs1374066376 714 dbSNP
rs1257935182 722 dbSNP
rs1451993229 729 dbSNP
rs373337066 730 dbSNP
rs1193775324 741 dbSNP
rs1026061648 742 dbSNP
rs1248065263 743 dbSNP
rs886310834 745 dbSNP
rs1195241440 751 dbSNP
rs1279460818 753 dbSNP
rs1232029664 754 dbSNP
rs1350013244 755 dbSNP
rs1003361180 756 dbSNP
rs1484102025 757 dbSNP
rs184069752 762 dbSNP
rs1393438778 767 dbSNP
rs1268831673 768 dbSNP
rs576859182 769 dbSNP
rs1433378328 770 dbSNP
rs959333358 770 dbSNP
rs1173713152 773 dbSNP
rs11542563 775 dbSNP
rs1469188008 776 dbSNP
rs1361649463 778 dbSNP
rs1183567323 780 dbSNP
rs11542562 781 dbSNP
rs1370928832 788 dbSNP
rs1256501746 794 dbSNP
rs1461162512 798 dbSNP
rs528177630 807 dbSNP
rs1281031131 808 dbSNP
rs990675968 813 dbSNP
rs1277949618 818 dbSNP
rs1422265876 818 dbSNP
rs1022258594 819 dbSNP
rs967990418 820 dbSNP
rs1377729259 821 dbSNP
rs1314035269 822 dbSNP
rs1366142529 823 dbSNP
rs978184749 826 dbSNP
rs1159836305 833 dbSNP
rs1470294669 838 dbSNP
rs1416790720 843 dbSNP
rs1185524410 845 dbSNP
rs1406467347 846 dbSNP
rs924028125 848 dbSNP
rs1293189894 854 dbSNP
rs550990376 862 dbSNP
rs1325697689 865 dbSNP
rs1226932333 866 dbSNP
rs934180292 874 dbSNP
rs1272789267 878 dbSNP
rs1271045441 881 dbSNP
rs1357785773 884 dbSNP
rs1285261877 888 dbSNP
rs1344351576 896 dbSNP
rs1430603773 899 dbSNP
rs1325248640 902 dbSNP
rs986998746 903 dbSNP
rs1220398602 905 dbSNP
rs911355179 909 dbSNP
rs942932315 918 dbSNP
rs1490660464 921 dbSNP
rs1212213729 930 dbSNP
rs1243846722 932 dbSNP
rs1195340693 936 dbSNP
rs1252556369 939 dbSNP
rs1260083499 941 dbSNP
rs1337277654 947 dbSNP
rs1428333043 949 dbSNP
rs1193424771 955 dbSNP
rs1374458926 958 dbSNP
rs1214406767 964 dbSNP
rs753186197 966 dbSNP
rs1442198553 967 dbSNP
rs1369635987 968 dbSNP
rs1323426945 971 dbSNP
rs545922536 980 dbSNP
rs1385720756 981 dbSNP
rs898865842 984 dbSNP
rs1426455833 989 dbSNP
rs930294187 996 dbSNP
rs1383948130 1000 dbSNP
rs1168447896 1007 dbSNP
rs1047535661 1008 dbSNP
rs1394527861 1010 dbSNP
rs1191881158 1012 dbSNP
rs759003839 1015 dbSNP
rs1469980917 1021 dbSNP
rs886177586 1026 dbSNP
rs1204182944 1027 dbSNP
rs1003675969 1030 dbSNP
rs1275658199 1039 dbSNP
rs1229824575 1040 dbSNP
rs1347837958 1043 dbSNP
rs1300613077 1044 dbSNP
rs1235946142 1047 dbSNP
rs1319189113 1050 dbSNP
rs559070575 1064 dbSNP
rs189098066 1065 dbSNP
rs764221269 1074 dbSNP
rs1356093756 1077 dbSNP
rs1308453800 1085 dbSNP
rs1434004368 1088 dbSNP
rs1314451435 1091 dbSNP
rs751569749 1103 dbSNP
rs1455644152 1108 dbSNP
rs1426062759 1111 dbSNP
rs1247584422 1114 dbSNP
rs377534760 1120 dbSNP
rs894934984 1121 dbSNP
rs1485717936 1128 dbSNP
rs1206373373 1129 dbSNP
rs1012129652 1130 dbSNP
rs796067594 1130 dbSNP
rs1278823448 1132 dbSNP
rs201161315 1134 dbSNP
rs1491026807 1135 dbSNP
rs541691638 1138 dbSNP
rs1305802707 1139 dbSNP
rs1221687145 1140 dbSNP
rs1182658522 1141 dbSNP
rs1243211772 1143 dbSNP
rs1375140199 1147 dbSNP
rs1425091756 1148 dbSNP
rs561662148 1150 dbSNP
rs1156781758 1155 dbSNP
rs1373479019 1163 dbSNP
rs1314662832 1164 dbSNP
rs1363189382 1166 dbSNP
rs1359845769 1168 dbSNP
rs1158522843 1169 dbSNP
rs530578631 1175 dbSNP
rs781267556 1175 dbSNP
rs968042142 1176 dbSNP
rs1414553950 1185 dbSNP
rs1183265916 1189 dbSNP
rs1475095075 1191 dbSNP
rs1255971692 1196 dbSNP
rs1190737674 1205 dbSNP
rs1483888112 1205 dbSNP
rs1259608587 1212 dbSNP
rs1213108355 1217 dbSNP
rs1318345602 1221 dbSNP
rs1268372881 1224 dbSNP
rs978047597 1228 dbSNP
rs1353353465 1234 dbSNP
rs1160103354 1237 dbSNP
rs1295004565 1238 dbSNP
rs1396499805 1240 dbSNP
rs1031389281 1241 dbSNP
rs1288347482 1251 dbSNP
rs375728256 1255 dbSNP
rs1450721315 1257 dbSNP
rs911401507 1261 dbSNP
rs1461218154 1262 dbSNP
rs1336369692 1266 dbSNP
rs34355767 1266 dbSNP
rs942837611 1267 dbSNP
rs974362271 1268 dbSNP
rs564536883 1271 dbSNP
rs1486569093 1282 dbSNP
rs1305434777 1284 dbSNP
rs930325500 1285 dbSNP
rs1323865722 1286 dbSNP
rs1332271152 1289 dbSNP
rs1274787393 1290 dbSNP
rs746889865 1291 dbSNP
rs907511207 1292 dbSNP
rs1141306 1297 dbSNP
rs1240134564 1298 dbSNP
rs939119956 1299 dbSNP
rs1321347546 1300 dbSNP
rs1440417716 1317 dbSNP
rs1392631258 1319 dbSNP
rs1295649432 1321 dbSNP
rs192423121 1324 dbSNP
rs1270399699 1325 dbSNP
rs1372949817 1327 dbSNP
rs1168980873 1331 dbSNP
rs1450749301 1337 dbSNP
rs1321937656 1342 dbSNP
rs1202603710 1344 dbSNP
rs1243400434 1345 dbSNP
rs1269102258 1350 dbSNP
rs1210157441 1352 dbSNP
rs1480202028 1355 dbSNP
rs1249507754 1359 dbSNP
rs1229483993 1360 dbSNP
rs1483924753 1361 dbSNP
rs1298405339 1366 dbSNP
rs1056584870 1368 dbSNP
rs1368964542 1371 dbSNP
rs895015940 1373 dbSNP
rs1387657430 1374 dbSNP
rs771139884 1375 dbSNP
rs532491147 1376 dbSNP
rs552676983 1377 dbSNP
rs1432141856 1379 dbSNP
rs1249668111 1383 dbSNP
rs1172467135 1387 dbSNP
rs1419591441 1394 dbSNP
rs1378957168 1398 dbSNP
rs1012013789 1400 dbSNP
rs1199172381 1402 dbSNP
rs1418193765 1406 dbSNP
rs565917062 1408 dbSNP
rs754699395 1410 dbSNP
rs1207106929 1414 dbSNP
rs535041774 1415 dbSNP
rs1426906969 1422 dbSNP
rs776846519 1426 dbSNP
rs903791199 1439 dbSNP
rs1210178219 1441 dbSNP
rs1342988140 1442 dbSNP
rs1257938970 1443 dbSNP
rs1234197582 1444 dbSNP
rs1175905980 1447 dbSNP
rs548868513 1452 dbSNP
rs1240585947 1455 dbSNP
rs1412136118 1460 dbSNP
rs999374198 1465 dbSNP
rs1359995246 1466 dbSNP
rs1403687260 1467 dbSNP
rs1172705226 1477 dbSNP
rs1031002114 1482 dbSNP
rs1361775428 1489 dbSNP
rs1183999638 1490 dbSNP
rs568770747 1492 dbSNP
rs778689633 1496 dbSNP
rs1185747416 1497 dbSNP
rs1280800884 1506 dbSNP
rs1201165602 1508 dbSNP
rs1018772664 1510 dbSNP
rs1266476060 1514 dbSNP
rs964230222 1531 dbSNP
rs974225123 1534 dbSNP
rs1293104785 1535 dbSNP
rs1372769001 1540 dbSNP
rs1342847318 1546 dbSNP
rs920063173 1548 dbSNP
rs1381169131 1553 dbSNP
rs1382254567 1555 dbSNP
rs1160952816 1565 dbSNP
rs537786942 1568 dbSNP
rs951628285 1571 dbSNP
rs1162581889 1578 dbSNP
rs1392474921 1584 dbSNP
rs1473728914 1584 dbSNP
rs1290793825 1586 dbSNP
rs983401281 1587 dbSNP
rs1223314844 1593 dbSNP
rs1465553784 1599 dbSNP
rs907545154 1601 dbSNP
rs939008911 1602 dbSNP
rs1056258487 1606 dbSNP
rs1202080107 1611 dbSNP
rs1250267388 1614 dbSNP
rs11542566 1615 dbSNP
rs1322014778 1615 dbSNP
rs1435330249 1616 dbSNP
rs772023623 1620 dbSNP
rs1207187535 1621 dbSNP
rs1266709087 1623 dbSNP
rs183084664 1625 dbSNP
rs1414363438 1627 dbSNP
rs1167297029 1630 dbSNP
rs1474409638 1637 dbSNP
rs1388378236 1638 dbSNP
rs550822843 1652 dbSNP
rs1465513956 1659 dbSNP
rs1426058923 1664 dbSNP
rs1043557079 1667 dbSNP
rs1435115029 1671 dbSNP
rs1291166468 1673 dbSNP
rs1195697723 1674 dbSNP
rs1168684618 1678 dbSNP
rs1299157099 1682 dbSNP
rs903655378 1686 dbSNP
rs1430537201 1687 dbSNP
rs1350222573 1696 dbSNP
rs775739861 1706 dbSNP
rs1327992520 1715 dbSNP
rs999456853 1717 dbSNP
rs1372404109 1718 dbSNP
rs1170497904 1721 dbSNP
rs577399588 1721 dbSNP
rs1052773457 1722 dbSNP
rs891166193 1722 dbSNP
rs1189728231 1727 dbSNP
rs1310350250 1730 dbSNP
rs916488474 1733 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaacacaaucuugucUCCGUUa 5'
                         |||||| 
Target 5' aacuauuccaucaauAGGCAAa 3'
 		9 - 30
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000372692.4 | 3UTR | AUAAAUGGAACUAUUCCAUCAAUAGGCAAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
75 hsa-miR-3152-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT092535 KBTBD8 kelch repeat and BTB domain containing 8 2 6
MIRT461731 NDUFA2 NADH:ubiquinone oxidoreductase subunit A2 2 2
MIRT468456 SET SET nuclear proto-oncogene 2 2
MIRT482192 AHR aryl hydrocarbon receptor 2 2
MIRT507923 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT512208 C18orf25 chromosome 18 open reading frame 25 2 6
MIRT526238 STARD4 StAR related lipid transfer domain containing 4 2 2
MIRT536131 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT536280 LIMA1 LIM domain and actin binding 1 2 2
MIRT544251 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT548054 GOLGA7 golgin A7 2 2
MIRT563443 ISCA1 iron-sulfur cluster assembly 1 2 2
MIRT565643 SIX4 SIX homeobox 4 2 2
MIRT614870 PDE12 phosphodiesterase 12 2 2
MIRT614923 MARCH6 membrane associated ring-CH-type finger 6 2 2
MIRT615793 FAM124A family with sequence similarity 124 member A 2 2
MIRT618557 VLDLR very low density lipoprotein receptor 2 2
MIRT622147 SORBS2 sorbin and SH3 domain containing 2 2 2
MIRT622390 RSBN1 round spermatid basic protein 1 2 2
MIRT624185 DDX19B DEAD-box helicase 19B 2 2
MIRT624448 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT625340 TAPBP TAP binding protein 2 2
MIRT625370 IRGQ immunity related GTPase Q 2 2
MIRT627276 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT627746 RAD54L2 RAD54 like 2 2 2
MIRT629578 RFC2 replication factor C subunit 2 2 4
MIRT630537 LGALS8 galectin 8 2 4
MIRT630559 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT630568 SOWAHA sosondowah ankyrin repeat domain family member A 2 4
MIRT630763 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT635424 LRP10 LDL receptor related protein 10 2 2
MIRT636011 GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 2 2
MIRT636337 PHAX phosphorylated adaptor for RNA export 2 2
MIRT638413 POU3F2 POU class 3 homeobox 2 2 2
MIRT639358 INIP INTS3 and NABP interacting protein 2 2
MIRT642124 DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A 2 4
MIRT642828 KIAA0319 KIAA0319 2 2
MIRT644017 NUCB1 nucleobindin 1 2 2
MIRT644038 WWC2 WW and C2 domain containing 2 2 2
MIRT644153 GIN1 gypsy retrotransposon integrase 1 2 2
MIRT644649 SNX9 sorting nexin 9 2 2
MIRT645798 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT647633 FAIM2 Fas apoptotic inhibitory molecule 2 2 2
MIRT648528 KIAA1143 KIAA1143 2 2
MIRT648851 PDLIM3 PDZ and LIM domain 3 2 2
MIRT648880 TUBGCP5 tubulin gamma complex associated protein 5 2 2
MIRT650777 TNFRSF10A TNF receptor superfamily member 10a 2 2
MIRT654200 RNF19B ring finger protein 19B 2 2
MIRT654508 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT655249 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT656089 MTA3 metastasis associated 1 family member 3 2 2
MIRT656599 LRRC55 leucine rich repeat containing 55 2 2
MIRT659194 CYBB cytochrome b-245 beta chain 2 2
MIRT660000 C1orf115 chromosome 1 open reading frame 115 2 4
MIRT661715 KLF8 Kruppel like factor 8 2 2
MIRT661813 PRPSAP1 phosphoribosyl pyrophosphate synthetase associated protein 1 2 2
MIRT668360 FGD4 FYVE, RhoGEF and PH domain containing 4 2 2
MIRT679734 CABP4 calcium binding protein 4 2 2
MIRT708616 NUDT18 nudix hydrolase 18 2 2
MIRT709034 TROVE2 TROVE domain family member 2 2 2
MIRT709573 DMGDH dimethylglycine dehydrogenase 2 2
MIRT709665 AJAP1 adherens junctions associated protein 1 2 2
MIRT709874 TRAF1 TNF receptor associated factor 1 2 2
MIRT710821 NLRP12 NLR family pyrin domain containing 12 2 2
MIRT710883 PARL presenilin associated rhomboid like 2 2
MIRT711547 LCAT lecithin-cholesterol acyltransferase 2 2
MIRT712017 STX1B syntaxin 1B 2 2
MIRT713058 BLVRA biliverdin reductase A 2 2
MIRT713129 THRB thyroid hormone receptor beta 2 2
MIRT713878 MOB3A MOB kinase activator 3A 2 2
MIRT714154 NXPH3 neurexophilin 3 2 2
MIRT719755 FLYWCH1 FLYWCH-type zinc finger 1 2 2
MIRT720213 KCNK1 potassium two pore domain channel subfamily K member 1 2 2
MIRT722728 BRMS1 breast cancer metastasis suppressor 1 2 2
MIRT725652 ABI2 abl interactor 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3152-5p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-3152-5p Palbociclib 5330286 NSC758247 approved resistant tissue (breast cancer)

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