pre-miRNA Information
pre-miRNA hsa-mir-758   
Genomic Coordinates chr14: 101026020 - 101026107
Synonyms MIRN758, hsa-mir-758, MIR758
Description Homo sapiens miR-758 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-758-3p
Sequence 52| UUUGUGACCUGGUCCACUAACC |73
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs992122694 10 dbSNP
rs1165305945 14 dbSNP
rs1432780238 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SEC24A   
Synonyms -
Description SEC24 homolog A, COPII coat complex component
Transcript NM_021982   
Expression
Putative miRNA Targets on SEC24A
3'UTR of SEC24A
(miRNA target sites are highlighted)
>SEC24A|NM_021982|3'UTR
   1 ATGAATGAAGAAATTTGACTTATTTTTAAGGAATGTCACGATAGTGCAGAATACCTGGAAATGTGTAATACCTTCTTTTT
  81 CTATTATGTTTGTGGACTAATGTGATGATTGAGATGTTCTCACTGTGATTTCAACAACCTATAGCAAATAAAAGACCACA
 161 GCAGAGAATCAAACATGCAACTCTGAAATACTGTATTTTTCAAATCAGAATATAGCTACGTATGATTGGATACTTTTTTC
 241 TTGCCAATTATGTTTGAGTTGTTATGGATTAAAATAAGAATATTGCAGAGGCAAAGTACATTTTGTAAAATAAAGATTTC
 321 TGTGTTCTACATGTATATTTCTCATTTTTAATTTTTCTGAATCTTTGGCTGCTACATTTAAAACCTCACAAACCTAAGTG
 401 TTGCAGGGAAGTTACAAATTGATTGGTAGTGATGTTTTTAAAATAAAAACAATGGAAAGTAAATATAATGTAGGAAAACT
 481 AGAATTCATTCCCCACACGTGTCTTTTTTTTTTCTTTGTTAAGGGAAAGGATCATGTTGACTAAAACTAAACTAATTCTA
 561 GTATAGCTTGAGAAAAATATGAAGAAACACATTCAAGCTTTAAAATCTGTCAGTATTCTTTATGCTTGAAGAACAAAGTC
 641 ACTTTGATTTGAAGTGAGAACTATCATTAGGTGGTTTTCTGATTTCCTGATGAAGAGTTGGACATACTGTCTTAATCTAT
 721 AGTGAAAAGAATTTGAGCTGTCTTCATAAACACTGGGACTAGCAATGATAATAGGGAGATAAGAAACTTTAATTATCTTG
 801 ATCCTTTAAGTGGATTTTATTTGGTGCATTTCTGCTCTGGGTATATAATAAAAGTGGGGGTTTTTGGTGAAATGAGTGAA
 881 GAAATGAAAGGTTTCTAAAGTGCTATCCAAATACATCAGTAACATTTTTCTAAGGAGTTTAATTGTTAAATTGGAAGTCA
 961 TTCATAAGAAATATTTATGCTTGAATATGAAAATCTATGAAAGCATAAATGCTGCTGTTTGATTTGGTGGATATTAAGAT
1041 TATACACATCCAACATATTAAAGTTATGAAAGAAACTTGACTTCTGAAAATCCTTAAGAGACTGCTTTCTTGATTCAGCT
1121 AGAGAAATATTATAGTCAAAACTATTGAGTGAATTTTGTTTACAAATAGGTAAATTATACATTTGTATATTTAAAGTGCT
1201 GTGACATAGTATCTTTAAGAGTTTGGCTCAGTTTTCACAGATTCATTTTGTCTTAAGAATTTCTTAAATATGTTCATGTA
1281 TAATACTTGATCAAAATATTTTTGGGTTTTTTGTTTTGTTTTAATGGGTTAGAAAATGTTTACAATCTTGGTCTTATATG
1361 ATCACCAATGGAATAGTAACTTCCAGGTTTATATCAATATGAGCTGACTTTAACTGAGTTGTTTGGGATAGGGAAGAAGC
1441 AGTCCCTCTACAGTATACAACTACTGCTTGCCAGCTGGATCAAAATAATCATGTTTTATGAAAATATCTCCCTTAAGCAG
1521 TGTTAAGGTTGGTTTGCAGTGTGTAAGTGGCACATTGAACTGGAAGTTTTCTTGAAAGCTGCTTCATCTATTAAGAAGCA
1601 ATTTTCAAATTGTAGCGAATTATATTATCCCCTCTTTTAAAGAAACAGTCGTTATATGCTGATGTTTCTTAAAATAACTA
1681 AAATGTTCCTCTTAATGTGATTTTAAATGGAGTTATTTGTAGGTCCTTTCTTAGTAGTAAAGAATCTTCTAGAGGGAAAC
1761 ATTTGTGCTTTTAGGGATAATCTTCCTTGTGCCTCACTACATCCCTAAGTGGGTATGACTCTTGTTATTACCACATGCTT
1841 TTTTAGTATATTTCACAAATTTACTTTTAAATATTATTTTAGATACGGTGTAACATGTGCAATTCAGAATAATTTTATAA
1921 CAGGTCATGAAAAACATAACTTTAGTTAGGATTCACAATATTTGTTCTCCACATAATGAGAGAATGAATGAGCCTTTGGA
2001 GATACTGATATAAGGCAATTATTTTTTGCAATGTTGAATGTGTTTTTTAGTTTGATTCTTTTTTTTTCCCCCAATAGGGC
2081 ACTACCTGCCATATCATCTTGTATTACTTTTTGATGTAAAGCGACTAATATTTACACTATGCCATATTTTTTTTAATTAT
2161 AGTTGTAAATTATGAAAGATCCTTGAATTTTCTACAGATCTACAACTACTAATGTAACAGACAAGGGCAATCTTGGTATT
2241 TAAATCTGAGCATGGCAGTTCTACCATAAAAAGTACTCTATTTTTCTAATTTCTAGGATTTTTAAAATAACATTTCTGTA
2321 AGTCTGACATACTAATAGTCACTCAAGCAGTACCATTTATTTTAGTTTGCATATATTTTCACTGTTTTTAATTTAATGTA
2401 TTGAGTCTAATAGACTGTTTTGCAATAATTAGAATAAAGATTTATTTCTTCTAATCAAAGATGCATAACAGCTATTATCT
2481 AGGGGACCACCAAATGTGATTTCAAAATTTTGTTAACTATTACAAATGTAATCCTTATATAGAAATTTTAATTTTGTAAA
2561 GTAGTGTATAATATTGTAATATTAAATTCTTGTTCTTAAATTCAAATATGTATTGATCTTCAATGTGCTGTGTTAAATCT
2641 TGCTTCTCTGAAAAGTTGGAGACAAGATTTGTCTTCCTTTTTACAGTTTGTAATTTTCACTGTTTTATTCCTGTTAAAAA
2721 AAAAAAAAAGTCATTTGTAACCCATGCAGACCATTGTTTGATCTATGCTAACTTATCAACTTGGCTATTCAATAAAGTTA
2801 ATTGAAAAGAGCTTATAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ccAAUCACCUGGUC----CAGUGUUu 5'
            | ||||   |||    ||:|||| 
Target 5' ccTAAGTGTTGCAGGGAAGTTACAAa 3'
393 - 418 138.00 -12.00
2
miRNA  3' ccAAUCACCUGGUCCAGUGUUu 5'
            |||  |||  | |||||:| 
Target 5' ttTTA-AGGA--ATGTCACGAt 3'
24 - 42 135.00 -10.40
3
miRNA  3' ccAAUCA--CCUGGUCCAGUGUUu 5'
            |||||  |||:    |||||| 
Target 5' ctTTAGTTAGGAT----TCACAAt 3'
1940 - 1959 131.00 -9.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31534113 19 COSMIC
COSN510586 20 COSMIC
COSN29241057 167 COSMIC
COSN31538712 220 COSMIC
COSN31480265 225 COSMIC
COSN31593993 454 COSMIC
COSN31528004 488 COSMIC
COSN21427438 537 COSMIC
COSN20101824 550 COSMIC
COSN32057726 652 COSMIC
COSN30250936 854 COSMIC
COSN2071213 1323 COSMIC
COSN31588290 1362 COSMIC
COSN31490953 1417 COSMIC
COSN20777324 1501 COSMIC
COSN2071214 1589 COSMIC
COSN20828921 1589 COSMIC
COSN31572061 1887 COSMIC
COSN18000788 2022 COSMIC
COSN24301076 2026 COSMIC
COSN18002087 2043 COSMIC
COSN18004658 2059 COSMIC
COSN31611251 2068 COSMIC
COSN31561664 2069 COSMIC
COSN31579429 2073 COSMIC
COSN20891712 2088 COSMIC
COSN14789083 2102 COSMIC
COSN24877223 2155 COSMIC
COSN32058715 2155 COSMIC
COSN23240877 2198 COSMIC
COSN31529766 2590 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs769184271 3 dbSNP
rs774670764 12 dbSNP
rs1423416972 24 dbSNP
rs748673398 29 dbSNP
rs1280647651 38 dbSNP
rs373289279 40 dbSNP
rs772495539 41 dbSNP
rs773723039 43 dbSNP
rs1026266799 47 dbSNP
rs760961523 52 dbSNP
rs1006629421 66 dbSNP
rs1193700241 73 dbSNP
rs1181611567 82 dbSNP
rs758890340 84 dbSNP
rs1206176866 91 dbSNP
rs1358792161 95 dbSNP
rs1289735879 100 dbSNP
rs1019817614 102 dbSNP
rs926657603 109 dbSNP
rs1357041285 110 dbSNP
rs938085608 119 dbSNP
rs534647193 120 dbSNP
rs1337347295 122 dbSNP
rs552704225 142 dbSNP
rs1404000940 146 dbSNP
rs567925242 149 dbSNP
rs1363127803 159 dbSNP
rs1165003060 167 dbSNP
rs1407560680 170 dbSNP
rs527577031 197 dbSNP
rs1158501084 213 dbSNP
rs1043004795 221 dbSNP
rs1162785158 229 dbSNP
rs1437491864 237 dbSNP
rs1490267545 240 dbSNP
rs1266850432 247 dbSNP
rs984504814 260 dbSNP
rs1034452087 262 dbSNP
rs1458957135 265 dbSNP
rs959069644 266 dbSNP
rs1288789684 273 dbSNP
rs1222514115 277 dbSNP
rs917786951 287 dbSNP
rs949190302 288 dbSNP
rs1286578262 289 dbSNP
rs535526566 291 dbSNP
rs1304594419 294 dbSNP
rs1436490033 297 dbSNP
rs901450707 299 dbSNP
rs557153229 304 dbSNP
rs977983527 306 dbSNP
rs934121527 312 dbSNP
rs1049892843 313 dbSNP
rs1399507515 316 dbSNP
rs1414647089 330 dbSNP
rs565349000 332 dbSNP
rs1480323002 335 dbSNP
rs1427383162 336 dbSNP
rs34628461 345 dbSNP
rs1193179324 366 dbSNP
rs936365236 376 dbSNP
rs1241642417 390 dbSNP
rs747709056 405 dbSNP
rs1053891670 406 dbSNP
rs150010229 411 dbSNP
rs1268508611 418 dbSNP
rs527786383 418 dbSNP
rs1037479984 430 dbSNP
rs1302902638 431 dbSNP
rs73297341 433 dbSNP
rs755797068 439 dbSNP
rs36047302 454 dbSNP
rs1267968424 475 dbSNP
rs1433513008 481 dbSNP
rs1245915184 483 dbSNP
rs1391399332 487 dbSNP
rs1316294597 499 dbSNP
rs1321816969 500 dbSNP
rs1026213471 502 dbSNP
rs1025919683 504 dbSNP
rs994297054 504 dbSNP
rs1323994114 511 dbSNP
rs1213789728 515 dbSNP
rs1418883711 519 dbSNP
rs1260201475 522 dbSNP
rs970637908 523 dbSNP
rs145165763 528 dbSNP
rs141234287 530 dbSNP
rs1033508421 531 dbSNP
rs959256458 534 dbSNP
rs201117126 546 dbSNP
rs112608734 548 dbSNP
rs200507067 548 dbSNP
rs10637666 550 dbSNP
rs200258447 551 dbSNP
rs1257592460 574 dbSNP
rs1210383244 581 dbSNP
rs958730261 583 dbSNP
rs915341979 584 dbSNP
rs967089286 585 dbSNP
rs978065370 586 dbSNP
rs1365337173 587 dbSNP
rs922822627 590 dbSNP
rs777525052 598 dbSNP
rs1050006241 602 dbSNP
rs1454006011 622 dbSNP
rs911372010 624 dbSNP
rs941568188 627 dbSNP
rs977868034 628 dbSNP
rs923786803 632 dbSNP
rs1337773385 635 dbSNP
rs936608701 646 dbSNP
rs115704486 652 dbSNP
rs749278201 657 dbSNP
rs1222564442 660 dbSNP
rs1162828434 664 dbSNP
rs898935472 668 dbSNP
rs993532984 670 dbSNP
rs1257994680 674 dbSNP
rs1182172170 681 dbSNP
rs1480188908 682 dbSNP
rs1306395701 686 dbSNP
rs1047419468 693 dbSNP
rs906236140 698 dbSNP
rs1342220000 699 dbSNP
rs748970497 700 dbSNP
rs1245883910 702 dbSNP
rs1261456952 705 dbSNP
rs1396909858 710 dbSNP
rs72800329 710 dbSNP
rs1373097538 713 dbSNP
rs1306357191 714 dbSNP
rs1202852288 720 dbSNP
rs188327885 727 dbSNP
rs959437648 738 dbSNP
rs1371210905 740 dbSNP
rs1010758363 743 dbSNP
rs1484197098 747 dbSNP
rs1165433473 752 dbSNP
rs1022761147 753 dbSNP
rs1047289850 756 dbSNP
rs371081504 758 dbSNP
rs1483219731 766 dbSNP
rs1347022334 773 dbSNP
rs978181724 780 dbSNP
rs1219552466 790 dbSNP
rs796831344 796 dbSNP
rs774083232 798 dbSNP
rs1160695711 799 dbSNP
rs1267715885 802 dbSNP
rs1246196976 804 dbSNP
rs1316674808 811 dbSNP
rs955398526 815 dbSNP
rs1426824784 820 dbSNP
rs1351277527 823 dbSNP
rs985664655 824 dbSNP
rs1034597489 825 dbSNP
rs894471528 829 dbSNP
rs778656759 841 dbSNP
rs1014187563 848 dbSNP
rs1386172765 852 dbSNP
rs911493017 854 dbSNP
rs745805111 858 dbSNP
rs1472806102 862 dbSNP
rs771952630 873 dbSNP
rs1200875312 881 dbSNP
rs1428086063 887 dbSNP
rs563224144 888 dbSNP
rs193297089 891 dbSNP
rs1434349904 892 dbSNP
rs1267501747 900 dbSNP
rs530347231 901 dbSNP
rs551882959 903 dbSNP
rs143625522 904 dbSNP
rs1374190095 920 dbSNP
rs1485865835 941 dbSNP
rs1411792099 954 dbSNP
rs745730260 959 dbSNP
rs998877922 964 dbSNP
rs1281431159 969 dbSNP
rs1282828000 999 dbSNP
rs1231397803 1006 dbSNP
rs1332871924 1010 dbSNP
rs929035776 1015 dbSNP
rs1031291279 1016 dbSNP
rs1224284279 1018 dbSNP
rs528330420 1019 dbSNP
rs1313687409 1025 dbSNP
rs1457539784 1028 dbSNP
rs1047534036 1029 dbSNP
rs1170424856 1040 dbSNP
rs906182213 1054 dbSNP
rs1202390891 1062 dbSNP
rs546506764 1068 dbSNP
rs939009443 1069 dbSNP
rs1377692814 1080 dbSNP
rs1232271825 1090 dbSNP
rs1447133869 1096 dbSNP
rs1483327585 1105 dbSNP
rs1191077520 1108 dbSNP
rs1055024153 1123 dbSNP
rs957889259 1128 dbSNP
rs989812448 1132 dbSNP
rs1198938779 1134 dbSNP
rs1183782739 1141 dbSNP
rs1256830374 1148 dbSNP
rs1226700848 1150 dbSNP
rs757076605 1190 dbSNP
rs775613033 1196 dbSNP
rs1299670715 1206 dbSNP
rs1266140610 1207 dbSNP
rs911101049 1224 dbSNP
rs1022120136 1225 dbSNP
rs1172745136 1227 dbSNP
rs1427725751 1236 dbSNP
rs568041149 1241 dbSNP
rs999547694 1251 dbSNP
rs1402389495 1254 dbSNP
rs1355680945 1263 dbSNP
rs929733070 1270 dbSNP
rs72800330 1272 dbSNP
rs1391532759 1273 dbSNP
rs879019899 1277 dbSNP
rs1301446934 1285 dbSNP
rs910073023 1298 dbSNP
rs941503036 1299 dbSNP
rs985446931 1311 dbSNP
rs1257078194 1313 dbSNP
rs1056469654 1318 dbSNP
rs1276789278 1320 dbSNP
rs1018905154 1324 dbSNP
rs1229048098 1340 dbSNP
rs1212636853 1355 dbSNP
rs1358716519 1358 dbSNP
rs1272003579 1361 dbSNP
rs963003840 1369 dbSNP
rs974766886 1377 dbSNP
rs1327737935 1416 dbSNP
rs550792336 1433 dbSNP
rs762024970 1438 dbSNP
rs983168603 1444 dbSNP
rs569248902 1447 dbSNP
rs958114455 1449 dbSNP
rs938958705 1451 dbSNP
rs1054806946 1459 dbSNP
rs1248139670 1464 dbSNP
rs1369459890 1475 dbSNP
rs1482236050 1482 dbSNP
rs894837009 1484 dbSNP
rs1474210766 1488 dbSNP
rs1451140545 1491 dbSNP
rs1186361787 1505 dbSNP
rs545454118 1515 dbSNP
rs1230005855 1517 dbSNP
rs1356747836 1518 dbSNP
rs374463438 1523 dbSNP
rs1044058857 1524 dbSNP
rs1451893833 1527 dbSNP
rs1162170025 1529 dbSNP
rs765625767 1548 dbSNP
rs1288589174 1554 dbSNP
rs1365068543 1554 dbSNP
rs963984763 1555 dbSNP
rs1347637343 1556 dbSNP
rs750807906 1570 dbSNP
rs999328660 1578 dbSNP
rs976646828 1592 dbSNP
rs1325580962 1604 dbSNP
rs1029680458 1609 dbSNP
rs891214743 1611 dbSNP
rs1391901766 1617 dbSNP
rs1471823172 1618 dbSNP
rs539922166 1621 dbSNP
rs758915730 1625 dbSNP
rs1477725866 1626 dbSNP
rs1018270162 1630 dbSNP
rs982945555 1638 dbSNP
rs558141629 1639 dbSNP
rs573287926 1651 dbSNP
rs941540804 1652 dbSNP
rs1312785536 1660 dbSNP
rs1206513318 1661 dbSNP
rs1055998344 1663 dbSNP
rs140741085 1666 dbSNP
rs570030710 1675 dbSNP
rs1364841540 1681 dbSNP
rs950343659 1686 dbSNP
rs951500870 1698 dbSNP
rs1209967572 1701 dbSNP
rs1291388339 1704 dbSNP
rs1320482514 1708 dbSNP
rs1455931131 1713 dbSNP
rs981608699 1717 dbSNP
rs1391348533 1718 dbSNP
rs1444992662 1720 dbSNP
rs1214549292 1724 dbSNP
rs1160137126 1727 dbSNP
rs1414184656 1732 dbSNP
rs1423133119 1734 dbSNP
rs1192931818 1738 dbSNP
rs927663271 1740 dbSNP
rs939074777 1742 dbSNP
rs1249059561 1752 dbSNP
rs1247293425 1753 dbSNP
rs1045954183 1756 dbSNP
rs1451673702 1760 dbSNP
rs538222253 1762 dbSNP
rs903200852 1766 dbSNP
rs1280313022 1778 dbSNP
rs1385210247 1789 dbSNP
rs565263037 1790 dbSNP
rs544472233 1801 dbSNP
rs766833720 1806 dbSNP
rs1054965597 1810 dbSNP
rs200385913 1819 dbSNP
rs1433575091 1826 dbSNP
rs1008043128 1827 dbSNP
rs1289874661 1832 dbSNP
rs946404245 1849 dbSNP
rs1357572029 1850 dbSNP
rs1178539599 1852 dbSNP
rs185370798 1860 dbSNP
rs1321413713 1871 dbSNP
rs747043874 1877 dbSNP
rs923878920 1877 dbSNP
rs1389153318 1879 dbSNP
rs755635772 1880 dbSNP
rs1018130663 1887 dbSNP
rs565398890 1888 dbSNP
rs998133649 1895 dbSNP
rs1238806602 1897 dbSNP
rs935128658 1898 dbSNP
rs1334425483 1903 dbSNP
rs1210444545 1913 dbSNP
rs1482424466 1917 dbSNP
rs1029549963 1921 dbSNP
rs1382019395 1924 dbSNP
rs1245425629 1937 dbSNP
rs1296920245 1940 dbSNP
rs188314873 1941 dbSNP
rs1304789658 1942 dbSNP
rs1377457733 1942 dbSNP
rs1347860862 1952 dbSNP
rs545894026 1955 dbSNP
rs1268413951 1958 dbSNP
rs1306323604 1969 dbSNP
rs1431720603 1971 dbSNP
rs1465956902 1974 dbSNP
rs1390644744 1978 dbSNP
rs1202232018 1987 dbSNP
rs777427363 1994 dbSNP
rs1006974892 2022 dbSNP
rs143742613 2033 dbSNP
rs1190148217 2034 dbSNP
rs1182082119 2043 dbSNP
rs748944320 2045 dbSNP
rs180731029 2049 dbSNP
rs1231279749 2052 dbSNP
rs1206589756 2059 dbSNP
rs948680797 2059 dbSNP
rs962518076 2059 dbSNP
rs1252351400 2065 dbSNP
rs979707227 2068 dbSNP
rs138908428 2073 dbSNP
rs991646820 2073 dbSNP
rs796459542 2077 dbSNP
rs1234120462 2081 dbSNP
rs909558593 2085 dbSNP
rs916113927 2092 dbSNP
rs995929398 2093 dbSNP
rs950186883 2100 dbSNP
rs148141277 2102 dbSNP
rs924843612 2103 dbSNP
rs1456388565 2108 dbSNP
rs561638210 2110 dbSNP
rs951616547 2123 dbSNP
rs112088844 2124 dbSNP
rs893107766 2132 dbSNP
rs1409257486 2136 dbSNP
rs745693977 2137 dbSNP
rs1336046749 2140 dbSNP
rs1333877172 2143 dbSNP
rs958884605 2144 dbSNP
rs1266106824 2145 dbSNP
rs1408738839 2146 dbSNP
rs1288412457 2147 dbSNP
rs577943705 2147 dbSNP
rs990571907 2155 dbSNP
rs1214634092 2156 dbSNP
rs1328945144 2160 dbSNP
rs1330850086 2163 dbSNP
rs1221232622 2169 dbSNP
rs771934786 2172 dbSNP
rs569040026 2181 dbSNP
rs1230505268 2190 dbSNP
rs1336420831 2191 dbSNP
rs1300746003 2195 dbSNP
rs967716613 2196 dbSNP
rs1369553581 2200 dbSNP
rs979512542 2206 dbSNP
rs923826898 2207 dbSNP
rs1386243166 2210 dbSNP
rs1262919796 2217 dbSNP
rs1160889200 2226 dbSNP
rs1454054677 2229 dbSNP
rs935244262 2232 dbSNP
rs997978117 2233 dbSNP
rs1051004123 2237 dbSNP
rs140167189 2245 dbSNP
rs760041762 2248 dbSNP
rs767977886 2250 dbSNP
rs1390440639 2251 dbSNP
rs1039766001 2252 dbSNP
rs1004520773 2253 dbSNP
rs6884245 2258 dbSNP
rs1246644945 2259 dbSNP
rs1210805810 2264 dbSNP
rs1351601817 2266 dbSNP
rs1255632270 2267 dbSNP
rs34981614 2268 dbSNP
rs1437738243 2274 dbSNP
rs1314041318 2279 dbSNP
rs1183065490 2286 dbSNP
rs1304036625 2294 dbSNP
rs768652458 2329 dbSNP
rs991262315 2333 dbSNP
rs184254140 2336 dbSNP
rs1382588462 2340 dbSNP
rs1022630910 2341 dbSNP
rs995485865 2343 dbSNP
rs1170480116 2347 dbSNP
rs1172387836 2354 dbSNP
rs1467088813 2354 dbSNP
rs1395212070 2358 dbSNP
rs1174809259 2363 dbSNP
rs1047085788 2372 dbSNP
rs776618145 2376 dbSNP
rs1404302732 2382 dbSNP
rs1388873433 2383 dbSNP
rs1195696035 2385 dbSNP
rs1447964724 2385 dbSNP
rs1255667138 2386 dbSNP
rs971558532 2391 dbSNP
rs776754776 2392 dbSNP
rs1198899478 2398 dbSNP
rs1376879966 2402 dbSNP
rs188783610 2414 dbSNP
rs1174085490 2416 dbSNP
rs924768144 2421 dbSNP
rs1299744009 2426 dbSNP
rs934950373 2427 dbSNP
rs1035975010 2442 dbSNP
rs555840826 2445 dbSNP
rs958873894 2465 dbSNP
rs150328223 2473 dbSNP
rs943330636 2475 dbSNP
rs1427263241 2482 dbSNP
rs538533846 2490 dbSNP
rs574522902 2492 dbSNP
rs1170167601 2497 dbSNP
rs1402737776 2499 dbSNP
rs1300121743 2504 dbSNP
rs979240534 2505 dbSNP
rs578136488 2510 dbSNP
rs1185682586 2511 dbSNP
rs1476344161 2512 dbSNP
rs923609461 2515 dbSNP
rs545466687 2517 dbSNP
rs933380150 2520 dbSNP
rs773593353 2524 dbSNP
rs1342159135 2534 dbSNP
rs1061131 2537 dbSNP
rs912495763 2539 dbSNP
rs1050939791 2540 dbSNP
rs763686620 2541 dbSNP
rs4320316 2543 dbSNP
rs116985068 2548 dbSNP
rs1004167340 2556 dbSNP
rs557257275 2562 dbSNP
rs975658992 2565 dbSNP
rs756764736 2566 dbSNP
rs1371918738 2567 dbSNP
rs1331421330 2569 dbSNP
rs575896168 2580 dbSNP
rs931386229 2583 dbSNP
rs898165280 2585 dbSNP
rs1161768613 2596 dbSNP
rs1012975267 2604 dbSNP
rs1022684749 2607 dbSNP
rs11538576 2608 dbSNP
rs577230221 2609 dbSNP
rs1448802405 2611 dbSNP
rs1234717156 2612 dbSNP
rs887094462 2629 dbSNP
rs766788328 2634 dbSNP
rs1002558667 2648 dbSNP
rs1450903174 2656 dbSNP
rs1287647835 2657 dbSNP
rs938676870 2668 dbSNP
rs1215289819 2678 dbSNP
rs1335261283 2686 dbSNP
rs1169084943 2687 dbSNP
rs1267071069 2688 dbSNP
rs1057375492 2693 dbSNP
rs1371898880 2697 dbSNP
rs1380662335 2716 dbSNP
rs1435150752 2716 dbSNP
rs747464196 2716 dbSNP
rs75553085 2716 dbSNP
rs1422261053 2717 dbSNP
rs1292417181 2721 dbSNP
rs1322185036 2728 dbSNP
rs374260672 2729 dbSNP
rs1443509331 2730 dbSNP
rs545374462 2733 dbSNP
rs1388152648 2752 dbSNP
rs1158667615 2755 dbSNP
rs1455909245 2766 dbSNP
rs894722434 2767 dbSNP
rs181224111 2777 dbSNP
rs1364851578 2802 dbSNP
rs1022204074 2803 dbSNP
rs904731349 2809 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 10802.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ccaaucaccugguccAGUGUUu 5'
                         |||||| 
Target 5' gcuacauuuaaaaccUCACAAa 3'
12 - 33
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ccaaucaccugguccAGUGUUu 5'
                         |||||| 
Target 5' gcuacauuuaaaaccUCACAAa 3'
12 - 33
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000398844.2 | 3UTR | AAUCUUUGGCUGCUACAUUUAAAACCUCACAAACCUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000398844.2 | 3UTR | AAUCUUUGGCUGCUACAUUUAAAACCUCACAAACCUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.889 2.4e-5 0.731 2.3e-3 13 Click to see details
GSE28544 Breast cancer 0.684 1.1e-4 0.582 1.4e-3 24 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.393 2.6e-2 0.468 9.2e-3 25 Click to see details
GSE21687 Ependynoma primary tumors 0.192 6.4e-2 0.138 1.4e-1 64 Click to see details
GSE17498 Multiple myeloma -0.169 1.5e-1 -0.131 2.1e-1 40 Click to see details
GSE17306 Multiple myeloma 0.131 1.8e-1 0.338 8.8e-3 49 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.203 2.0e-1 0.355 6.2e-2 20 Click to see details
GSE19783 ER+ ER+ breast cancer 0.18 2.2e-1 0.233 1.6e-1 20 Click to see details
GSE19536 Breast cancer 0.065 2.6e-1 0.093 1.8e-1 100 Click to see details
GSE19350 CNS germ cell tumors -0.104 3.7e-1 -0.077 4.1e-1 12 Click to see details
GSE21849 B cell lymphoma -0.054 3.9e-1 0.380 2.1e-2 29 Click to see details
GSE19783 ER- ER- breast cancer 0.02 4.3e-1 0.053 3.2e-1 79 Click to see details
GSE32688 Pancreatic cancer 0.011 4.8e-1 -0.020 4.6e-1 32 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.002 5.0e-1 -0.183 1.9e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.002 5.0e-1 -0.183 1.9e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LUAD -0.587 0.02 -0.552 0.03 12 Click to see details
KIRC 0.249 0.04 0.213 0.06 52 Click to see details
HNSC -0.156 0.16 -0.165 0.15 42 Click to see details
CESC -0.83 0.19 -0.500 0.33 3 Click to see details
BLCA 0.214 0.2 0.276 0.13 18 Click to see details
THCA 0.115 0.21 0.073 0.31 50 Click to see details
STAD 0.144 0.22 0.055 0.38 32 Click to see details
BRCA 0.081 0.23 0.068 0.27 84 Click to see details
KICH 0.143 0.26 0.260 0.12 23 Click to see details
KIRP -0.11 0.29 0.026 0.45 29 Click to see details
LIHC -0.08 0.29 -0.091 0.27 49 Click to see details
UCEC 0.119 0.31 0.189 0.22 19 Click to see details
PCPG -0.54 0.32 -0.500 0.33 3 Click to see details
CHOL -0.134 0.37 -0.133 0.37 9 Click to see details
PAAD -0.258 0.37 0.400 0.3 4 Click to see details
PRAD 0.045 0.38 0.067 0.32 50 Click to see details
LUSC 0.052 0.38 0.017 0.46 38 Click to see details
ESCA 0.011 0.49 -0.309 0.18 11 Click to see details
COAD -0.009 0.49 0.238 0.29 8 Click to see details
COAD -0.009 0.49 0.238 0.29 8 Click to see details
COAD -0.009 0.49 0.238 0.29 8 Click to see details
48 hsa-miR-758-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118609 NCOA3 nuclear receptor coactivator 3 2 2
MIRT122451 SMIM13 small integral membrane protein 13 2 2
MIRT438602 TLR7 toll like receptor 7 3 1
MIRT438603 TLR3 toll like receptor 3 3 1
MIRT446951 CD248 CD248 molecule 2 2
MIRT447942 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT450648 TMEM70 transmembrane protein 70 2 2
MIRT463976 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT465151 TSC22D2 TSC22 domain family member 2 2 2
MIRT468670 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469019 RNF41 ring finger protein 41 2 2
MIRT475623 HMGA1 high mobility group AT-hook 1 2 4
MIRT485794 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT492982 NAV1 neuron navigator 1 2 2
MIRT493720 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT498889 RBM12B RNA binding motif protein 12B 2 4
MIRT499194 TJAP1 tight junction associated protein 1 2 2
MIRT499331 RAB25 RAB25, member RAS oncogene family 2 2
MIRT510550 WTAP WT1 associated protein 2 4
MIRT524405 COL4A1 collagen type IV alpha 1 chain 2 4
MIRT530160 C11orf44 chromosome 11 open reading frame 44 2 2
MIRT534595 RORA RAR related orphan receptor A 2 2
MIRT538452 CNKSR2 connector enhancer of kinase suppressor of Ras 2 2 2
MIRT543494 MDM2 MDM2 proto-oncogene 2 4
MIRT547860 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT553785 TACC1 transforming acidic coiled-coil containing protein 1 2 2
MIRT553903 SUN2 Sad1 and UNC84 domain containing 2 2 4
MIRT559303 ATXN1 ataxin 1 2 2
MIRT563350 ZNF181 zinc finger protein 181 2 2
MIRT565404 TFDP1 transcription factor Dp-1 2 2
MIRT566891 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT613227 CCDC39 coiled-coil domain containing 39 2 2
MIRT613470 TG thyroglobulin 2 4
MIRT619930 WSCD2 WSC domain containing 2 2 2
MIRT627180 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT632962 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT634304 SNTN sentan, cilia apical structure protein 2 2
MIRT635292 IRX2 iroquois homeobox 2 2 2
MIRT639740 SLC1A1 solute carrier family 1 member 1 2 2
MIRT641892 SMNDC1 survival motor neuron domain containing 1 2 2
MIRT645871 PRRG3 proline rich and Gla domain 3 2 2
MIRT648691 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT650048 KRBA1 KRAB-A domain containing 1 2 2
MIRT667626 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT669725 A1CF APOBEC1 complementation factor 2 2
MIRT710429 BTNL3 butyrophilin like 3 2 2
MIRT710805 SLC4A1AP solute carrier family 4 member 1 adaptor protein 2 2
MIRT723980 SOX17 SRY-box 17 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-758 Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-758 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-758 5-Fluorouracil approved 3385 Quantitative real-time PCR human squamous cell carcinoma cell line KYSE410 21743970 2011 up-regulated
miR-758 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-758 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-758-3p (1-(((2-amino-6-chloro-4-pyrimidinyl)amino)methyl)-3-isopropylcyclobutyl)methanol 385230 NSC676343 sensitive
hsa-miR-758-3p (2e)-2-hydroxyimino-4-(3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-yl)-4-oxo-n-(2,4,5-trichlorophenyl)butanamide 6399319 NSC635544 resistant
hsa-miR-758-3p (2E,5Z)-2-[(5-acetyl-4-methyl-1,3-thiazol-2-yl)hydrazinylidene]-5-[(2-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one 135472679 NSC658292 sensitive
hsa-miR-758-3p (2S,6S,7S,12R)-16-bromo-9-tert-butyl-4-phenyl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 372657 NSC648154 sensitive
hsa-miR-758-3p (3-(trifluoromethyl)anilino)(2-(trifluoromethyl)phenyl)acetonitrile 375079 NSC654017 resistant
hsa-miR-758-3p (3e)-3-[(2-chloro-1-phenylindol-3-yl)methylidene]-5-methoxy-1h-indol-2-one 5471470 NSC711610 sensitive
hsa-miR-758-3p (4E)-2-(2-hydroxybenzoyl)-5-methyl-4-[(4-nitrophenyl)methylidene]pyrazol-3-one 5467414 NSC652175 sensitive
hsa-miR-758-3p (E)-1-[4-(quinazolin-4-ylamino)phenyl]-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one 155816064 NSC760015 sensitive
hsa-miR-758-3p (E)-3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-methylamino]-2-oxoethyl]prop-2-enamide 51003603 NSC761184 resistant
hsa-miR-758-3p (NE)-N-[(6E)-2-[(hydroxyamino)-(4-phenylmethoxyphenyl)methyl]-6-[(4-phenylmethoxyphenyl)methylidene]cyclohexylidene]hydroxylamine 5928828 NSC632824 resistant
hsa-miR-758-3p [(11bR)-9,10-dimethoxy-4-phenylimino-2,6,7,11b-tetrahydro-1H-[1,3]thiazino[4,3-a]isoquinolin-1-yl]methyl benzoate 371073 NSC645016 sensitive
hsa-miR-758-3p [(1s,2s,3r,4s,7r,9s,10s,12r,15s)-4,12-diacetyloxy-15-[(2r,3s)-3-benzamido-2-hydroxy-3-(2-methylphenyl)propanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]hepta 383478 NSC671870 sensitive
hsa-miR-758-3p [(4e)-4-[2-(3,3,6a,10b-tetramethyl-8-methylidene-1,4a,5,6,7,9,10,10a-octahydronaphtho[2,1-d][1,3]dioxin-7-yl)ethylidene]-5-oxooxolan-3-yl] acetate 25121273 NSC750035 resistant
hsa-miR-758-3p [1-[[[2-amino-6-chloro-5-[(4-chlorophenyl)diazenyl]pyrimidin-4-yl]amino]methyl]-3-phenylmethoxycyclobutyl]methanol 385284 NSC676395 resistant
hsa-miR-758-3p [5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [5-[5-fluoro-4-(octadecylamino)-2-oxopyrimidin-1-yl]-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate 390213 NSC687370 sensitive
hsa-miR-758-3p [acetyl-[5-(trityloxymethyl)spiro[3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole-2,1'-cyclopentane]-6-yl]amino] acetate 374290 NSC651809 sensitive
hsa-miR-758-3p {2-[(benzylamino)methyl]-1h-indole-1,3-diyl}bis(phenylmethanone) 374841 NSC653267 sensitive
hsa-miR-758-3p 1-(2-methoxyphenyl)-3-[(z)-1-(2-pyridyl)ethylideneamino]thiourea 5367237 NSC668297 resistant
hsa-miR-758-3p 1-(9-methoxy-11,12-dihydro-6h-indolo[1,2-b][2]benzazepin-13-yl)ethanone 365697 NSC633551 sensitive
hsa-miR-758-3p 1-[(4-bromophenyl)amino]cyclopentanecarbonitrile 238637 NSC43101 resistant
hsa-miR-758-3p 1-[5-[[[4-chlorobutyl(methyl)amino]-[(5-nitrofuran-2-yl)methoxy]phosphoryl]oxymethyl]-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione 404846 NSC721390 sensitive
hsa-miR-758-3p 1-benzyl-2-methyl-1-(2-phenylethyl)-4,5-dihydroimidazol-1-ium 413544 NSC49460 sensitive
hsa-miR-758-3p 16-methoxy-4-(4-methoxyphenyl)-9-propan-2-yl-4,20-diazapentacyclo[11.7.0.02,6.07,12.014,19]icosa-1(13),14(19),15,17-tetraene-3,5-dione 390916 NSC689137 sensitive
hsa-miR-758-3p 17-acetyl-9,14-dihydroxy-16-methyl-15-(4-methylphenyl)-15-azatetracyclo[8.7.0.01,14.03,8]heptadeca-3,5,7,9,12,16-hexaene-2,11-dione 405612 NSC722982 resistant
hsa-miR-758-3p 2'-(4-chlorobenzoyl)-1'-(4-chlorophenyl)-1'-hydroxyspiro[1,3-dihydro-1-benzazepine-4,4'-cyclohexane]-2,5-dione 388188 NSC682756 sensitive
hsa-miR-758-3p 2-(4-chlorophenyl)-1-methylene-3-phenyl-pyrazino[1,2-a]benzimidazole 390230 NSC687522 resistant
hsa-miR-758-3p 2-(hydroxymethyl)-5-[6-(2-propan-2-ylidenehydrazinyl)purin-9-yl]oxolane-3,4-diol 60147745 NSC752330 resistant
hsa-miR-758-3p 2-(trifluoromethyl)benzimidazo[2,1-b][1,3,5]benzothiadiazepin-12(13h)-imine 383194 NSC671313 sensitive
hsa-miR-758-3p 2-[2-[5-(ethoxycarbonylcarbamoyl)-3-methyl-2,4-dioxopyrimidin-1-yl]ethylsulfanyl]ethyl n-[6-[2-[2-[5-(ethoxycarbonylcarbamoyl)-3-methyl-2,4-dioxopyrimidin-1-yl]ethylsulfanyl]ethoxycarbonylamino]hexyl] 367630 NSC637505 sensitive
hsa-miR-758-3p 2-[2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]acetic acid 5934333 NSC643813 sensitive
hsa-miR-758-3p 2-[9-[(7-oxocyclohepta-1,3,5-trien-1-yl)amino]nonylamino]cyclohepta-2,4,6-trien-1-one 358331 NSC618296 sensitive
hsa-miR-758-3p 2-acetyl-1,2-dihydroellipticine 376328 NSC657149 resistant
hsa-miR-758-3p 2-azaadenine 5480214 NSC57048 resistant
hsa-miR-758-3p 2-methyl-1-[10-[(2-methylquinolin-4-yl)amino]decyl]quinolin-1-ium-4-amine;chloride;hydrochloride 387885 NSC682096 sensitive
hsa-miR-758-3p 2-methyl-4,4-diphenyl-1,4-benzoxaphosphinin-4-ium;bromide 24199840 NSC346098 sensitive
hsa-miR-758-3p 2-methylellpticinium 21123185 NSC351710 sensitive
hsa-miR-758-3p 2-methylolivacinium acetate 5458752 NSC336003 sensitive
hsa-miR-758-3p 2-n-methyl-6-thiaellipticinum iodide 367888 NSC638066 sensitive
hsa-miR-758-3p 2,2'-spirobi[indane]-5,5'-dicarbaldehyde 382743 NSC670421 sensitive
hsa-miR-758-3p 2,3-dibenzoyloxy-4-hydroxy-4-oxobutanoate;(2,5-dimethylphenyl)-(4-methylphenyl)-phenylsulfanium 5351228 NSC116693 sensitive
hsa-miR-758-3p 2,5-dibenzyl-2-undecyloctahydro-1h-pyrrolo[3,4-c]pyridin-2-ium bromide 378731 NSC661832 sensitive
hsa-miR-758-3p 2,5,11-trimethyl-9-phenoxy-6h-pyrido[4,3-b]carbazol-2-ium;acetate 10431819 NSC650269 sensitive
hsa-miR-758-3p 2,5,12-trimethyl-[1,4]benzodioxino[3,2-g]isoquinolin-2-ium acetate 388316 NSC683048 sensitive
hsa-miR-758-3p 3-(4-methoxyphenyl)-4-methyl-8-pyrrolidin-1-yl-8H-thieno[2,3-b]pyrrolizin-4-ium;iodide 388538 NSC683518 sensitive
hsa-miR-758-3p 3-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)-1,4-dioxane-2,6-diol 269951 NSC111702 resistant
hsa-miR-758-3p 3-bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5h)-furanone 11413833 NSC726328 resistant
hsa-miR-758-3p 3,3-bis(3-(trifluoromethyl)phenyl)naphtho[1,2-c]furan-1(3h)-one 362080 NSC625603 sensitive
hsa-miR-758-3p 4-(4-carbazol-9-ylbutanoylamino)-n-[5-[3-(dimethylamino)propylcarbamoyl]-1-methylpyrrol-3-yl]-1-methylpyrrole-2-carboxamide 406397 NSC724462 sensitive
hsa-miR-758-3p 4-(bromomethyl)-2,2,5,5-tetramethyl-1-imidazolidinol 3-oxide 378673 NSC661470 resistant
hsa-miR-758-3p 4-[(13R)-13-hydroxy-13-[(2S,5S)-5-[(2S,5S)-5-[1-hydroxy-13-[(2S)-2-methyl-5-oxo-2H-furan-4-yl]tridecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]-2-methyl-2H-furan-5-one 374064 NSC651320 sensitive
hsa-miR-758-3p 4-[[(Z)-N-benzamido-C-[4-[bis(2-cyanoethyl)amino]-2-methylphenyl]carbonimidoyl]diazenyl]benzoic acid 135493923 NSC681974 sensitive
hsa-miR-758-3p 4-[4-(diethylamino)phenyl]-2-(4-hydroxypiperidin-1-yl)-6-(3,4,5-trimethoxyphenyl)pyridine-3-carbonitrile 60148088 NSC753601 resistant
hsa-miR-758-3p 4-[4-[2,3-bis(hydroxymethyl)pyrrol-1-yl]butanoylamino]-n-[5-[[5-[3-(dimethylamino)propylcarbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-1-methylpyrrole-2-carboxamide 384021 NSC673131 sensitive
hsa-miR-758-3p 4-methoxy-1,5-benzothiazepine-1,1-dioxide 358940 NSC619102 resistant
hsa-miR-758-3p 4-methyl-1,1-diphenyl-1,2,3,4-tetrahydrobenzo(h)phosphinolinium hexafluorophosphate 498151 NSC245398 sensitive
hsa-miR-758-3p 4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1H-2-benzofuran-1-yl)-N-[3-(trifluoromethyl)phenyl]butanamide 369471 NSC641241 sensitive
hsa-miR-758-3p 4-pyridin-3-yl-2-(2,3,5-trichlorophenyl)-1,3-thiazole 24814783 NSC742842 resistant
hsa-miR-758-3p 4,10-bis(3-ethynylphenyl)-4,10-diazatetracyclo[5.5.2.02,6.08,12]tetradec-13-ene-3,5,9,11-tetrone 365547 NSC633253 sensitive
hsa-miR-758-3p 5-benzyl-5h-benzo[b]phosphindole 5-oxide 380786 NSC666496 sensitive
hsa-miR-758-3p 5-hydroxy-3,7-dimethoxy-3',4'-methylenedioxyflavone 5466137 NSC678102 sensitive
hsa-miR-758-3p 5-methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 NSC748147 sensitive
hsa-miR-758-3p 5,11-dimethyl-2-[(pentanoyloxy)methyl]-6h-pyrido[4,3-b]carbazol-2-ium iodide 367409 NSC637130 sensitive
hsa-miR-758-3p 6-aminotoyocamycin 300567 NSC175630 resistant
hsa-miR-758-3p 6-bromosangivamycin 270853 NSC113943 resistant
hsa-miR-758-3p 6,7-dimethyl-4-[(2z)-2-(5-oxooxolan-2-ylidene)ethoxy]chromen-2-one 24205380 NSC735332 resistant
hsa-miR-758-3p 7'-but-3-en-2-yl-7'-(3-phenylmethoxypropyl)spiro[1,3-dioxolane-2,2'-3,4,7a,8,9,10-hexahydro-1h-cyclopenta[i]indolizine]-6'-thione 361486 NSC624523 sensitive
hsa-miR-758-3p 7-[(3-fluorophenyl)methoxy]-9-[(3-fluorophenyl)methyl]-2-[(4-fluorophenyl)methyl]-1-methylpyrido[3,4-b]indol-2-ium 54766740 NSC760181 sensitive
hsa-miR-758-3p 7-hydroxy-2-nonyl-4h-chromen-4-one 5375154 NSC631965 sensitive
hsa-miR-758-3p 8-(6-fluorohexyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;hydrochloride 380336 NSC665863 resistant
hsa-miR-758-3p 8-[3-(1,3-dioxolan-2-yl)-2-(4-fluorophenyl)propyl]-3-ethyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;hydrochloride 380308 NSC665789 resistant
hsa-miR-758-3p 8-aminoadenosine 259812 NSC90394 resistant
hsa-miR-758-3p 8-chloro-7-methyl-5,5-dioxo-n-phenyl-[1,2,4]triazolo[4,3-b][1,4,2]benzodithiazin-3-amine 400657 NSC713019 sensitive
hsa-miR-758-3p 8-chloro-7-methyl-n-(4-methylphenyl)-5,5-dioxo-[1,2,4]triazolo[4,3-b][1,4,2]benzodithiazin-3-amine 400656 NSC713018 sensitive
hsa-miR-758-3p 8-trichloromethyldihydroberberine 320713 NSC269192 sensitive
hsa-miR-758-3p 9-((2-chloroethyl)thio)acridine 395387 NSC699923 resistant
hsa-miR-758-3p 9-(benzylsulfinyl)-2,7-dimethoxyacridine 395397 NSC699933 resistant
hsa-miR-758-3p 9-bromo-2,3-dimethoxy-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one 395805 NSC700693 resistant
hsa-miR-758-3p 9-hydroxy-2-(.beta.-diethylaminoethyl)ellipticinium acetate 72034 NSC311152 sensitive
hsa-miR-758-3p Berberine iodide 72350 NSC150446 sensitive
hsa-miR-758-3p Di-n-octyl-secalonsaure a 430141 NSC268925 sensitive
hsa-miR-758-3p Diaporthein b 54612739 NSC751295 resistant
hsa-miR-758-3p Diethyl (Z)-2-(2,4-dioxo-3-prop-2-ynylpyrimidin-1-yl)but-2-enedioate 5469884 NSC693983 resistant
hsa-miR-758-3p Diethyl 4-hydroxy-2-(4-methoxyphenyl)-6-oxo-4-phenyl-1,3-cyclohexanedicarboxylate 386764 NSC679443 sensitive
hsa-miR-758-3p Ellipticine 3213 NSC71795 sensitive
hsa-miR-758-3p Elliptinium acetate 42722 NSC264137 sensitive
hsa-miR-758-3p Ethyl (E)-3-(6-methoxy-1-thiophen-3-yl-3,4-dihydronaphthalen-2-yl)prop-2-enoate 24205739 NSC736553 sensitive
hsa-miR-758-3p Ethyl 16-(3,4-dimethoxyphenyl)-12,14-diphenyl-10-oxa-3,5,6,8,12,13-hexazatetracyclo[7.7.0.02,6.011,15]hexadeca-1(9),2,4,7,11(15),13-hexaene-4-carboxylate 391836 NSC691424 sensitive
hsa-miR-758-3p Fixierer p 70397 NSC63839 resistant
hsa-miR-758-3p Gtpl10345 378629 NSC661421 resistant
hsa-miR-758-3p Gw701427a 10276395 NSC756323 sensitive
hsa-miR-758-3p Haloprogin 3561 NSC100071 resistant
hsa-miR-758-3p Heteromine a 391982 NSC691767 sensitive
hsa-miR-758-3p Hexyl (e)-3-[(2s,4z)-2-(hydroxymethyl)-4-(4-methyl-3-propan-2-ylpentylidene)-5-oxooxolan-2-yl]prop-2-enoate 5471817 NSC714070 sensitive
hsa-miR-758-3p Hsdb 8106 16129719 NSC676825 resistant
hsa-miR-758-3p Inosine, 6-thio-, 2',3',5'-tripentanoate 4208664 NSC77495 resistant
hsa-miR-758-3p Isobaccharin 5358646 NSC269760 sensitive
hsa-miR-758-3p Isobrucein a 322357 NSC279503 sensitive
hsa-miR-758-3p J3.522.543i 6163542 NSC113053 resistant
hsa-miR-758-3p Kinetin riboside 3832 NSC120958 resistant
hsa-miR-758-3p Kuc100204 378309 NSC660313 sensitive
hsa-miR-758-3p Laurusin 135476719 NSC106486 resistant
hsa-miR-758-3p Maxima isoflavone d 343081 NSC382028 sensitive
hsa-miR-758-3p Mefloquine hydrochloride 456309 NSC157387 resistant
hsa-miR-758-3p Methyl (Z)-4,4-dicyano-4-[(3-methoxyphenyl)methylideneamino]but-2-enoate 5470182 NSC698278 resistant
hsa-miR-758-3p Methyl 4-[3-(2-thienyl)quinoxalin-2-yl]oxybenzoate 388002 NSC682365 sensitive
hsa-miR-758-3p Musennin 267361 NSC106554 sensitive
hsa-miR-758-3p N'-[(Z)-[(4Z)-2-(1,3-benzodioxol-5-yl)-4-[[4-oxo-4-[2-(trifluoromethyl)anilino]butanoyl]hydrazinylidene]chromen-3-ylidene]amino]-N-[2-(trifluoromethyl)phenyl]butanediamide 6399328 NSC641210 sensitive
hsa-miR-758-3p N'-chloro-4-[2-[2-[4-[(Z)-N'-chlorocarbamimidoyl]phenoxy]ethyl-(4-methylphenyl)sulfonylamino]ethoxy]benzenecarboximidamide 45028721 NSC743909 sensitive
hsa-miR-758-3p N-(6-methyl-1,3-benzothiazol-2-yl)-4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1h-2-benzofuran-1-yl)butanamide 369455 NSC641225 sensitive
hsa-miR-758-3p N-[(z)-[phenyl(pyridin-2-yl)methylidene]amino]quinoxalin-2-amine 5869744 NSC693626 resistant
hsa-miR-758-3p N-[2-(dimethylamino)ethyl]-4-(furo[3,2-c]quinolin-4-ylamino)benzamide 24204686 NSC732490 resistant
hsa-miR-758-3p N-[2-chloro-5-(trifluoromethyl)phenyl]-4-naphthalen-2-yl-2,4-dioxo-3-(3-oxo-1h-2-benzofuran-1-yl)butanamide 369469 NSC641239 sensitive
hsa-miR-758-3p N-benzyl-1-[10-[4-(benzylamino)-2-methylquinolin-1-ium-1-yl]decyl]-2-methylquinolin-1-ium-4-amine;perchlorate 387881 NSC682094 sensitive
hsa-miR-758-3p N,n-dimethyl-4-[(e)-2-(1-methyl-2,5-diphenylpyrazol-1-ium-3-yl)ethenyl]aniline;trifluoromethanesulfonate 5469868 NSC693576 sensitive
hsa-miR-758-3p None 12201866 NSC179207 resistant
hsa-miR-758-3p NSC644919 NSC644919 sensitive
hsa-miR-758-3p NSC699071 NSC699071 sensitive
hsa-miR-758-3p NSC751830 NSC751830 resistant
hsa-miR-758-3p Oxidanium;1,3-diphenylpropane-1,3-dione;neodymium(3+);hydroxide 24202397 NSC647042 sensitive
hsa-miR-758-3p Phenoxathiin-2-ylmethyl carbamimidothioate;hydrochloride 392088 NSC691900 resistant
hsa-miR-758-3p Phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) 10714966 NSC289922 sensitive
hsa-miR-758-3p Propan-2-ylsulfanyl-(2,3,5,6-tetrachloropyridin-4-yl)sulfanylmethanethione 399833 NSC710969 resistant
hsa-miR-758-3p Protein: pahiv4 NSC678525 sensitive
hsa-miR-758-3p Pyrazolanthrone 8515 NSC75890 resistant
hsa-miR-758-3p Pyrimido[5,4-g]pteridine-2,4,6,8(1h,3h,7h,9h)-tetrone, 1,9-bis(methoxymethyl)-3,7-dimethyl-, 5-oxide 385097 NSC676032 sensitive
hsa-miR-758-3p Sarcoviolin 24202820 NSC726045 sensitive
hsa-miR-758-3p Stl298328 387753 NSC681782 resistant
hsa-miR-758-3p Stl323035 383655 NSC672073 sensitive
hsa-miR-758-3p Stl361983 256661 NSC83715 resistant
hsa-miR-758-3p Tetramethyl (1r,5r,6s,9s)-7-[4-[(e)-2,3-bis(4-chlorophenyl)prop-2-enoyl]oxyphenyl]-3,5-dihydroxybicyclo[3.3.1]non-2-ene-2,4,6,9-tetracarboxylate 54681588 NSC717067 resistant
hsa-miR-758-3p Tris(1,10-phenanthroline)lanthanum(iii)-trithiocyanate 24202211 NSC632737 resistant
hsa-miR-758-3p Xestin a 5352066 NSC647638 resistant
hsa-miR-758-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Etoposide 36462 NSC141540 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-758-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive Low Esophageal Cancer cell line (ECA-109)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-758-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-3p Paclitaxel 36314 NSC125973 approved resistant cell line (HeyA8)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-758-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM47)
hsa-miR-758-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-758-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-758-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (K562)
hsa-miR-758-3p Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR70)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-758-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-758-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVCAR3)
hsa-miR-758-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)
hsa-miR-758-3p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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