pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-3p
Sequence 51| AGAAGGCACUAUGAGAUUUAGA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 10 + 51299626 27587585, 28550310, 26028588, 26449202, 26487287, 29165639 MiREDiBase
A-to-I 14 10 + 51299636 29233923 MiREDiBase
A-to-I 20 10 + 51299642 18684997, 26449202, 27587585, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs759219082 5 dbSNP
rs1491224174 9 dbSNP
rs746611214 10 dbSNP
rs367648737 11 dbSNP
rs1359467239 14 dbSNP
rs1442565019 16 dbSNP
Putative Targets

Gene Information
Gene Symbol OTUB1   
Synonyms HSPC263, OTB1, OTU1
Description OTU deubiquitinase, ubiquitin aldehyde binding 1
Transcript NM_017670   
Expression
Putative miRNA Targets on OTUB1
3'UTR of OTUB1
(miRNA target sites are highlighted)
>OTUB1|NM_017670|3'UTR
   1 GGCTGGCTCCAGCCCGCTGCTGCCCTGCTGCCCCCCTCTGCCAGGCGCTAGACATGTACAGAGGTTTTTCTGTGGTTGTA
  81 AATGGTCCTATTTCACCCCCTTCTTCCTGTCACATGACCCCCCCCCATGTTTTATTAAAGGGGGTGCTGGTGGTGAGCCG
 161 TGTGTGCGTGTCCCTGCTCTGCTGCCCGCCTGGCTGCTCTGTCTGCTGCCCCCTCCCCCCAGGTGGGTCCCCCTGCTTTT
 241 CACCTATCTACTCCTGAGCTTCCCCAACAGGAGCAGGTTTGAGGGGCCAGGCCTCTTGGAGGCCCCTCCTGCTTCGTTGG
 321 GTTCTGCTTCCTTCCCTTCTTAGCTGGCTCAGGGGCTTCTATGGGATCCTGGAAGTTCCTTAGGGACTTGCCCAGGGTCC
 401 CAGGGCCACCCACACTTCATCTGCTCCCTCATAGGCCCCACCTCCACGTCCCGGCTGGGCCCCAGACCCCAGCTTCCTGC
 481 CCTCCACCGGGAGTCTGCATGGTTGGGAGTCCTGGGTGGAGGGGCCTTTGTGAGGCTGGACCCGGCTCAGGGCAGGTGGA
 561 GGAGCTGGGCCTCCCACAGGGTGCCCGGGCAGTGCCATCCTGGTGGGGGAGGGCAGCCTTCAAACGTGTGGGGTCTACAG
 641 TCCTCAGGTCTAGGCAGGGCTGCCGGTTCTCCACCTCCCCATCCGCCCCAGGCCCCCTGCCTGTGCCTGCCTTGCACCCC
 721 CTCTGCTTGGGCCACGGTGTCTCTGCATTGCCTGCCTTTTTGCCTTCACCTCTTTTCTTCCCCGCCCCCTGCACATTCGG
 801 GGTCTCAGCCCCCAGGCTGTGAGCTCCTTGGGGGCAGGCCCTCAATAAATGTGAACTGCTGCTGCCGCCTCTGCAAAAAA
 881 AAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' agauuuaGAGUAUCACGGAAGa 5'
                 ||: |  ||||||| 
Target 5' tgcctgcCTTTT--TGCCTTCa 3'
749 - 768 143.00 -8.70
2
miRNA  3' agauuuagaguaucACGGAAga 5'
                        ||||||  
Target 5' cccctgcctgtgccTGCCTTgc 3'
694 - 715 120.00 -7.12
3
miRNA  3' agauuuagaguaucaCGGAAGa 5'
                         |||||| 
Target 5' tggtgggggagggcaGCCTTCa 3'
601 - 622 120.00 -8.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30478388 25 COSMIC
COSN26987682 46 COSMIC
COSN30144328 82 COSMIC
COSN30108676 89 COSMIC
COSN30161162 107 COSMIC
COSN30112455 112 COSMIC
COSN509855 127 COSMIC
COSN30552782 168 COSMIC
COSN22608092 216 COSMIC
COSN1080355 230 COSMIC
COSN27227860 473 COSMIC
COSN31481087 485 COSMIC
COSN28807151 672 COSMIC
COSN28755177 697 COSMIC
COSN31588803 840 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs776958806 3 dbSNP
rs773483542 6 dbSNP
rs1207596350 15 dbSNP
rs375063755 16 dbSNP
rs760868231 16 dbSNP
rs746137458 17 dbSNP
rs758973863 17 dbSNP
rs766486922 17 dbSNP
rs997364635 18 dbSNP
rs769977704 27 dbSNP
rs1488450230 28 dbSNP
rs370933976 31 dbSNP
rs753983822 31 dbSNP
rs763301304 32 dbSNP
rs764672942 35 dbSNP
rs1477342238 36 dbSNP
rs1053383 39 dbSNP
rs552928353 47 dbSNP
rs1471755430 48 dbSNP
rs753467887 51 dbSNP
rs781314211 56 dbSNP
rs1222914913 59 dbSNP
rs1053384 62 dbSNP
rs566483037 64 dbSNP
rs1318874417 74 dbSNP
rs1015523974 89 dbSNP
rs1216626612 91 dbSNP
rs1041965141 95 dbSNP
rs759485891 96 dbSNP
rs765234884 96 dbSNP
rs754683223 97 dbSNP
rs764727163 98 dbSNP
rs535517488 99 dbSNP
rs555298563 100 dbSNP
rs3209355 104 dbSNP
rs752571431 104 dbSNP
rs757051140 115 dbSNP
rs1465686019 117 dbSNP
rs781187157 117 dbSNP
rs1474653404 118 dbSNP
rs35556442 118 dbSNP
rs35611728 118 dbSNP
rs533490120 118 dbSNP
rs959222172 119 dbSNP
rs1283093679 120 dbSNP
rs746083572 122 dbSNP
rs770144495 123 dbSNP
rs575478020 124 dbSNP
rs1198299570 127 dbSNP
rs372981070 127 dbSNP
rs917639985 130 dbSNP
rs749406153 135 dbSNP
rs1257998174 136 dbSNP
rs1440699823 138 dbSNP
rs1491006858 139 dbSNP
rs769006797 140 dbSNP
rs780657767 140 dbSNP
rs1441569111 141 dbSNP
rs1006014792 142 dbSNP
rs1379961393 143 dbSNP
rs966350290 149 dbSNP
rs1338699569 151 dbSNP
rs112341603 159 dbSNP
rs544528368 160 dbSNP
rs770224696 161 dbSNP
rs558039727 163 dbSNP
rs1330084624 164 dbSNP
rs577996825 168 dbSNP
rs1448400886 169 dbSNP
rs1390928483 170 dbSNP
rs1306425244 171 dbSNP
rs1164200341 173 dbSNP
rs1352599994 174 dbSNP
rs1233519259 178 dbSNP
rs1257548634 179 dbSNP
rs897505875 180 dbSNP
rs1342546594 186 dbSNP
rs993136780 188 dbSNP
rs1238673430 189 dbSNP
rs1176480356 193 dbSNP
rs1459011455 193 dbSNP
rs1440808661 196 dbSNP
rs1176907489 197 dbSNP
rs1237633303 198 dbSNP
rs1377066519 200 dbSNP
rs1433986061 202 dbSNP
rs1179681858 203 dbSNP
rs1464470373 204 dbSNP
rs1178431952 207 dbSNP
rs1376306910 209 dbSNP
rs1465816833 210 dbSNP
rs759126650 214 dbSNP
rs1403143927 215 dbSNP
rs924940220 216 dbSNP
rs1328776219 218 dbSNP
rs1375434434 221 dbSNP
rs1387010295 222 dbSNP
rs1030683450 223 dbSNP
rs545918979 224 dbSNP
rs1329166879 227 dbSNP
rs1199168911 228 dbSNP
rs1232313157 229 dbSNP
rs55951521 230 dbSNP
rs1319994745 231 dbSNP
rs528607400 233 dbSNP
rs1017475595 234 dbSNP
rs757892062 242 dbSNP
rs763558263 244 dbSNP
rs921463819 244 dbSNP
rs1051199652 247 dbSNP
rs891176840 249 dbSNP
rs1265581232 253 dbSNP
rs1432794482 257 dbSNP
rs751498385 263 dbSNP
rs1382633467 266 dbSNP
rs1426225028 267 dbSNP
rs914629897 271 dbSNP
rs1464526081 272 dbSNP
rs1469679601 276 dbSNP
rs1247560975 282 dbSNP
rs967370411 288 dbSNP
rs542279886 289 dbSNP
rs1267942582 290 dbSNP
rs1216993309 293 dbSNP
rs1489231610 298 dbSNP
rs1341303598 303 dbSNP
rs1282055587 304 dbSNP
rs1222763109 316 dbSNP
rs1037070263 317 dbSNP
rs1276071110 318 dbSNP
rs1230639938 337 dbSNP
rs1344417479 343 dbSNP
rs898476250 345 dbSNP
rs995857337 354 dbSNP
rs928612850 356 dbSNP
rs938982062 362 dbSNP
rs1400234116 370 dbSNP
rs1425999387 372 dbSNP
rs1209227534 375 dbSNP
rs1242293841 383 dbSNP
rs1476209363 386 dbSNP
rs1056448391 392 dbSNP
rs1479586153 399 dbSNP
rs1013379614 403 dbSNP
rs1389023447 405 dbSNP
rs1024685094 411 dbSNP
rs1454377144 416 dbSNP
rs1174806466 419 dbSNP
rs1248049190 422 dbSNP
rs916084666 436 dbSNP
rs1442887778 440 dbSNP
rs942143040 440 dbSNP
rs1280146687 443 dbSNP
rs374487504 446 dbSNP
rs1201164003 447 dbSNP
rs3802940 448 dbSNP
rs977807252 449 dbSNP
rs3802939 453 dbSNP
rs1333945251 454 dbSNP
rs1268746252 456 dbSNP
rs1430671559 460 dbSNP
rs746797387 460 dbSNP
rs1166452220 461 dbSNP
rs1468292244 463 dbSNP
rs957716761 463 dbSNP
rs1405696194 466 dbSNP
rs1171619164 469 dbSNP
rs1437568194 471 dbSNP
rs993229608 484 dbSNP
rs1185659886 488 dbSNP
rs796718192 489 dbSNP
rs76826727 490 dbSNP
rs1235169107 497 dbSNP
rs373062787 499 dbSNP
rs1258350172 500 dbSNP
rs1342816723 507 dbSNP
rs534025853 508 dbSNP
rs940109534 510 dbSNP
rs1284701821 513 dbSNP
rs550865540 524 dbSNP
rs1037104638 525 dbSNP
rs1206421170 542 dbSNP
rs1450599392 543 dbSNP
rs1247098123 544 dbSNP
rs564485257 545 dbSNP
rs34901004 551 dbSNP
rs1169568096 562 dbSNP
rs1405726914 565 dbSNP
rs1415939010 569 dbSNP
rs1161564037 575 dbSNP
rs1017902759 583 dbSNP
rs1238275020 584 dbSNP
rs1179906595 587 dbSNP
rs112989429 588 dbSNP
rs1231949556 593 dbSNP
rs377502278 598 dbSNP
rs1204332879 600 dbSNP
rs895025990 601 dbSNP
rs1010671010 604 dbSNP
rs1244455819 605 dbSNP
rs1359281886 610 dbSNP
rs1310092279 625 dbSNP
rs1020724963 627 dbSNP
rs1393213934 638 dbSNP
rs533665662 639 dbSNP
rs1297800362 651 dbSNP
rs1409160373 659 dbSNP
rs1351437985 660 dbSNP
rs879229700 663 dbSNP
rs1024802586 665 dbSNP
rs977901578 666 dbSNP
rs147616481 672 dbSNP
rs1160002559 675 dbSNP
rs999261539 676 dbSNP
rs1191379428 680 dbSNP
rs1032024908 682 dbSNP
rs957962464 684 dbSNP
rs747102438 685 dbSNP
rs974395703 686 dbSNP
rs1287357729 687 dbSNP
rs577979511 693 dbSNP
rs1029001836 694 dbSNP
rs566438952 704 dbSNP
rs1232455311 707 dbSNP
rs954354822 714 dbSNP
rs987049564 715 dbSNP
rs912763343 717 dbSNP
rs991764396 718 dbSNP
rs1290531197 721 dbSNP
rs972830363 722 dbSNP
rs919983632 731 dbSNP
rs535214863 733 dbSNP
rs1055164318 735 dbSNP
rs942196599 737 dbSNP
rs1426769766 738 dbSNP
rs1197790950 740 dbSNP
rs895134440 742 dbSNP
rs1335101249 743 dbSNP
rs1053405 744 dbSNP
rs1207444380 748 dbSNP
rs760284878 754 dbSNP
rs549024430 758 dbSNP
rs919414369 769 dbSNP
rs528435392 771 dbSNP
rs1210823239 772 dbSNP
rs1046287510 773 dbSNP
rs1340859636 773 dbSNP
rs569080024 773 dbSNP
rs1051908978 782 dbSNP
rs890133095 784 dbSNP
rs1007606634 785 dbSNP
rs1038968506 788 dbSNP
rs1302993262 795 dbSNP
rs1470665176 796 dbSNP
rs35621932 796 dbSNP
rs1175226586 799 dbSNP
rs893748346 799 dbSNP
rs1010764297 800 dbSNP
rs1063848 805 dbSNP
rs1473764415 809 dbSNP
rs748444085 809 dbSNP
rs1157436115 810 dbSNP
rs73496075 817 dbSNP
rs966514488 823 dbSNP
rs996321313 830 dbSNP
rs998953546 831 dbSNP
rs1203306878 835 dbSNP
rs1318810191 836 dbSNP
rs1252862573 841 dbSNP
rs1224966025 842 dbSNP
rs1165021599 856 dbSNP
rs1325848503 856 dbSNP
rs557975589 857 dbSNP
rs960081755 860 dbSNP
rs954346455 862 dbSNP
rs1008496726 865 dbSNP
rs1447081391 866 dbSNP
rs1019853954 867 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000538426.1 | 3UTR | CCUUCACCUCUUUUCUUCCCCGCCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
100 hsa-miR-605-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061339 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT061584 BTG2 BTG anti-proliferation factor 2 2 6
MIRT076140 WDR81 WD repeat domain 81 2 2
MIRT079361 CCDC137 coiled-coil domain containing 137 2 2
MIRT079547 VAMP3 vesicle associated membrane protein 3 2 2
MIRT096242 CANX calnexin 2 2
MIRT243877 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT249186 AKIRIN1 akirin 1 2 8
MIRT273604 SP1 Sp1 transcription factor 2 2
MIRT316766 FOXC1 forkhead box C1 2 4
MIRT322410 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT370117 TRIB3 tribbles pseudokinase 3 2 2
MIRT392725 UBN2 ubinuclein 2 2 2
MIRT406910 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT407440 CTDSP1 CTD small phosphatase 1 2 2
MIRT441887 RD3 retinal degeneration 3 2 4
MIRT444979 C15orf52 chromosome 15 open reading frame 52 2 2
MIRT445241 FOXD4 forkhead box D4 2 2
MIRT445500 FOXD4L5 forkhead box D4 like 5 2 2
MIRT445503 FOXD4L4 forkhead box D4 like 4 2 2
MIRT447025 FOXD4L1 forkhead box D4 like 1 2 2
MIRT447743 TMCC3 transmembrane and coiled-coil domain family 3 2 2
MIRT448761 HDX highly divergent homeobox 2 2
MIRT450003 HAX1 HCLS1 associated protein X-1 2 2
MIRT452830 FAM131B family with sequence similarity 131 member B 2 2
MIRT452872 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT453506 ARRB1 arrestin beta 1 2 2
MIRT454169 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT458742 CES2 carboxylesterase 2 2 2
MIRT459166 HSPA6 heat shock protein family A (Hsp70) member 6 2 21
MIRT460246 IL17RB interleukin 17 receptor B 2 4
MIRT460514 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460698 RNF157 ring finger protein 157 2 2
MIRT461481 METTL1 methyltransferase like 1 2 2
MIRT462617 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT463233 ZNF131 zinc finger protein 131 2 2
MIRT465699 TNPO2 transportin 2 2 8
MIRT466304 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT468957 RPS14 ribosomal protein S14 2 6
MIRT469571 RARA retinoic acid receptor alpha 2 2
MIRT469685 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT470800 PMP22 peripheral myelin protein 22 2 2
MIRT471649 PANK2 pantothenate kinase 2 2 4
MIRT471722 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472281 NFIB nuclear factor I B 2 4
MIRT473680 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT475859 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT477326 EPHA2 EPH receptor A2 2 2
MIRT477831 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478572 CTNND1 catenin delta 1 2 4
MIRT479634 CD81 CD81 molecule 2 2
MIRT481950 ANKRD11 ankyrin repeat domain 11 2 2
MIRT483696 ZNF74 zinc finger protein 74 2 6
MIRT488798 MALT1 MALT1 paracaspase 2 2
MIRT489066 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT492533 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT492857 NRARP NOTCH regulated ankyrin repeat protein 2 2
MIRT496793 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT500122 ZNF106 zinc finger protein 106 2 4
MIRT505359 TMEM167A transmembrane protein 167A 2 2
MIRT506786 KLHL15 kelch like family member 15 2 6
MIRT510692 SRM spermidine synthase 2 6
MIRT515841 CEP104 centrosomal protein 104 2 4
MIRT516448 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT528855 PKP1 plakophilin 1 2 2
MIRT533848 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT539025 ATXN7L1 ataxin 7 like 1 2 4
MIRT542872 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT546543 SATB2 SATB homeobox 2 2 2
MIRT554114 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT560569 ZNF460 zinc finger protein 460 2 2
MIRT560796 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562836 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT563109 IFRD2 interferon related developmental regulator 2 2 2
MIRT564177 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT564283 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT564350 USP22 ubiquitin specific peptidase 22 2 2
MIRT565279 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT565338 TMEM104 transmembrane protein 104 2 2
MIRT565905 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT567108 ITGB1 integrin subunit beta 1 2 2
MIRT567601 FANCF Fanconi anemia complementation group F 2 2
MIRT567779 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568075 CENPQ centromere protein Q 2 2
MIRT624304 COL12A1 collagen type XII alpha 1 chain 2 2
MIRT644395 CDKL1 cyclin dependent kinase like 1 2 2
MIRT661547 ZNF674 zinc finger protein 674 2 4
MIRT670949 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT672951 AKAP5 A-kinase anchoring protein 5 2 2
MIRT697426 ZFP36 ZFP36 ring finger protein 2 2
MIRT700793 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT702657 ITGA3 integrin subunit alpha 3 2 2
MIRT708945 FZR1 fizzy and cell division cycle 20 related 1 2 2
MIRT713657 PLCE1 phospholipase C epsilon 1 2 2
MIRT719239 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719951 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT722048 HLA-E major histocompatibility complex, class I, E 2 2
MIRT722201 URM1 ubiquitin related modifier 1 2 2
MIRT724790 C1D C1D nuclear receptor corepressor 2 2
MIRT734347 CYP2B6 cytochrome P450 family 2 subfamily B member 6 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)

Error report submission