miRTarBase - #MIRT472929


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pre-miRNA Information
pre-miRNA hsa-mir-4697   
Genomic Coordinates chr11: 133898504 - 133898581
Description Homo sapiens miR-4697 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4697-5p
Sequence 10| AGGGGGCGCAGUCACUGACGUG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs549326907 2 dbSNP
rs897782230 7 dbSNP
rs748950280 8 dbSNP
rs978998780 15 dbSNP
rs968922289 19 dbSNP
rs3802919 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MSN   
Synonyms HEL70, IMD50
Description moesin
Transcript NM_002444   
Expression
Putative miRNA Targets on MSN
3'UTR of MSN
(miRNA target sites are highlighted)		 
>MSN|NM_002444|3'UTR
   1 TGGGCACCCAGCCTCTAGGGACCCCTCCTCCCTTTTTCCTTGTCCCCACACTCCTACACCTAACTCACCTAACTCATACT
  81 GTGCTGGAGCCACTAACTAGAGCAGCCCTGGAGTCATGCCAAGCATTTAATGTAGCCATGGGACCAAACCTAGCCCCTTA
 161 GCCCCCACCCACTTCCCTGGGCAAATGAATGGCTCACTATGGTGCCAATGGAACCTCCTTTCTCTTCTCTGTTCCATTGA
 241 ATCTGTATGGCTAGAATATCCTACTTCTCCAGCCTAGAGGTACTTTCCACTTGATTTTGCAAATGCCCTTACACTTACTG
 321 TTGTCCTATGGGAGTCAAGTGTGGAGTAGGTTGGAAGCTAGCTCCCCTCCTCTCCCCTACCACTGTCTTCTTCAGGGTCC
 401 TGAGATTTACACGGTTGGAGTGTTATGCGGTCTAGGGAATGAGACAGGACCTAGGATATCTTCTCCAGGATGTCAACTGA
 481 CCTAAAATTTGCCCTCCCATCCCGTTTAGAGTTATTTAGGCTTTGTAACGATTGGGGGATAAAAAGATGTTCAGTCATTT
 561 TTGTTTCTACCTCCCAGATCGGATCTGTTGCAAACTCAGCCTCAATAAGCCTTGTCGTTGACTTTAGGGACTCAATTTCT
 641 CCCCAGGGTGGATGGGGGAAATGGTGCCTTCAAGACCTTCACCAAACATACTAGAAGGGCATTGGCCATTCTATTGTGGC
 721 AAGGCTGAGTAGAAGATCCTACCCCAATTCCTTGTAGGAGTATAGGCCGGTCTAAAGTGAGCTCTATGGGCAGATCTACC
 801 CCTTACTTATTATTCCAGATCTGCAGTCACTTCGTGGGATCTGCCCCTCCCTGCTTCAATACCCAAATCCTCTCCAGCTA
 881 TAACAGTAGGGATGAGTACCCAAAAGCTCAGCCAGCCCCATCAGGACTCTTGTGAAAAGAGAGGATATGTTCACACCTAG
 961 CGTCAGTATTTTCCCTGCTAGGGGTTTTAGGTCTCTTCCCCTCTCAGAGCTACTTGGGCCATAGCTCCTGCTCCACAGCC
1041 ATCCCAGCCTTGGCATCTAGAGCTTGATGCCAGTAGGCTCAACTAGGGAGTGAGTGCAAAAAGCTGAGTATGGTGAGAGA
1121 AGCCTGTGCCCTGATCCAAGTTTACTCAACCCTCTCAGGTGACCAAAATCCCCTTCTCATCACTCCCCTCCAAAGAGGTG
1201 ACTGGGCCCTGCCTCTGTTTGACAAACCTCTAACCCAGGTCTTGACACCAGCTGTTCTGTCCCTTGGAGCTGTAAACCAG
1281 AGAGCTGCTGGGGATTCTGGCCTAGTCCCTTCCACACCCCCACCCCTTGCTCTCAACCCAGGAGCATCCACCTCCTTCTC
1361 TGTCTCATGTGTGCTCTTCTTCTTTCTACAGTATTATGTACTCTACTGATATCTAAATATTGATTTCTGCCTTCCTTGCT
1441 AATGCACCATTAGAAGATATTAGTCTTGGGGCAGGATGATTTTGGCCTCATTACTTTACCACCCCCACACCTGGAAAGCA
1521 TATACTATATTACAAAATGACATTTTGCCAAAATTATTAATATAAGAAGCTTTCAGTATTAGTGATGTCATCTGTCACTA
1601 TAGGTCATACAATCCATTCTTAAAGTACTTGTTATTTGTTTTTATTATTACTGTTTGTCTTCTCCCCAGGGTTCAGTCCT
1681 CAAGGGGCCATCCTGTCCCACCATGCAGTGCCCCTAGCTTAGAGCCTCCCTCAATTCCCCCTGGCCACCACCCCCCACTC
1761 TGTGCCTGACCTTGAGGAGTCTTGTGTGCATTGCTGTGAATTAGCTCACTTGGTGATATGTCCTATATTGGCTAAATTGA
1841 AACCTGGAATTGTGGGGCAATCTATTAATAGCTGCCTTAAAGTCAGTAACTTACCCTTAGGGAGGCTGGGGGAAAAGGTT
1921 AGATTTTGTATTCAGGGGTTTTTTGTGTACTTTTTGGGTTTTTTAAAAATTGTTTTTGGAGGGGTTTATGCTCAATCCAT
2001 GTTCTATTTCAGTGCCAATAAAATTTAGGAAGACTTCAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guGCAG-UCACUG------ACGCGGGGGa 5'
            :||| | ||||      | :||||:| 
Target 5' gaTGTCAACTGACCTAAAATTTGCCCTCc 3'
 469 - 497 122.00 -17.90
2 
miRNA  3' gugCAGU----CA-CUGACGCGGGGGa 5'
             ||||    || |: | :|||||: 
Target 5' gcaGTCACTTCGTGGGATCTGCCCCTc 3'
 823 - 849 121.00 -21.20
3 
miRNA  3' gugcagucacugacgCGGGGGa 5'
                         |||||| 
Target 5' aaacctagccccttaGCCCCCa 3'
 146 - 167 120.00 -13.00
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1173032160 4 dbSNP
rs761832582 7 dbSNP
rs1269975179 10 dbSNP
rs1480960211 13 dbSNP
rs1193300751 14 dbSNP
rs12848169 16 dbSNP
rs199555040 20 dbSNP
rs1477933173 21 dbSNP
rs750456923 23 dbSNP
rs1171253188 24 dbSNP
rs756228649 25 dbSNP
rs780086751 32 dbSNP
rs1295199712 34 dbSNP
rs1213861586 36 dbSNP
rs1445846320 38 dbSNP
rs1284195190 39 dbSNP
rs754120838 44 dbSNP
rs1258988874 53 dbSNP
rs1281736288 54 dbSNP
rs1223183336 57 dbSNP
rs1341385924 60 dbSNP
rs1280264350 69 dbSNP
rs1438455127 80 dbSNP
rs749706173 82 dbSNP
rs1221131873 106 dbSNP
rs1334831748 107 dbSNP
rs760700786 110 dbSNP
rs1489357143 114 dbSNP
rs1465913376 118 dbSNP
rs368747210 131 dbSNP
rs909161987 133 dbSNP
rs1190976357 150 dbSNP
rs1237543990 152 dbSNP
rs1188897540 162 dbSNP
rs943169183 163 dbSNP
rs187113694 165 dbSNP
rs757600387 170 dbSNP
rs1318967022 178 dbSNP
rs1260301595 197 dbSNP
rs1170408057 198 dbSNP
rs1361410949 200 dbSNP
rs1284835227 204 dbSNP
rs1419682531 204 dbSNP
rs779239241 209 dbSNP
rs1335923140 215 dbSNP
rs1162299369 227 dbSNP
rs1402177922 235 dbSNP
rs1168173909 240 dbSNP
rs138533310 244 dbSNP
rs762943489 246 dbSNP
rs1413950112 259 dbSNP
rs1164517295 262 dbSNP
rs746040931 267 dbSNP
rs1471500365 270 dbSNP
rs1052749431 274 dbSNP
rs763854299 277 dbSNP
rs1458547522 278 dbSNP
rs947090537 281 dbSNP
rs1436722535 284 dbSNP
rs1043276625 294 dbSNP
rs1290815399 298 dbSNP
rs751349326 299 dbSNP
rs772218546 314 dbSNP
rs1001634565 317 dbSNP
rs1314361622 329 dbSNP
rs1035833536 335 dbSNP
rs895865570 351 dbSNP
rs775376495 367 dbSNP
rs994661770 376 dbSNP
rs1441147832 384 dbSNP
rs1350141193 401 dbSNP
rs1325038686 407 dbSNP
rs568007621 413 dbSNP
rs1340156484 414 dbSNP
rs746949134 429 dbSNP
rs1163554581 430 dbSNP
rs952813020 435 dbSNP
rs1382652863 442 dbSNP
rs1175884960 452 dbSNP
rs1247521727 468 dbSNP
rs1005583054 477 dbSNP
rs757008703 479 dbSNP
rs767237421 480 dbSNP
rs1489898465 489 dbSNP
rs1291091237 492 dbSNP
rs1323777955 494 dbSNP
rs111345693 504 dbSNP
rs1247257672 505 dbSNP
rs776696631 530 dbSNP
rs192766716 533 dbSNP
rs1368024856 558 dbSNP
rs780611354 567 dbSNP
rs1276317206 568 dbSNP
rs1016168645 577 dbSNP
rs964640292 578 dbSNP
rs1190447235 581 dbSNP
rs974542284 582 dbSNP
rs923102843 592 dbSNP
rs1347472379 598 dbSNP
rs1157489522 606 dbSNP
rs1418916006 617 dbSNP
rs764900526 618 dbSNP
rs749824409 624 dbSNP
rs755494945 633 dbSNP
rs113578197 636 dbSNP
rs1217477402 644 dbSNP
rs184459095 646 dbSNP
rs1489273493 647 dbSNP
rs1258905771 652 dbSNP
rs1214978314 657 dbSNP
rs187743488 659 dbSNP
rs1312599664 665 dbSNP
rs913010414 675 dbSNP
rs6525006 677 dbSNP
rs947036713 683 dbSNP
rs1278365187 690 dbSNP
rs1401325596 691 dbSNP
rs1359234298 698 dbSNP
rs1455918014 708 dbSNP
rs571835485 728 dbSNP
rs1042722593 730 dbSNP
rs762453466 748 dbSNP
rs6525007 755 dbSNP
rs1179058361 764 dbSNP
rs1468527474 769 dbSNP
rs1428864993 770 dbSNP
rs1194585201 776 dbSNP
rs1478882310 779 dbSNP
rs927521659 782 dbSNP
rs1185911305 783 dbSNP
rs1282536197 784 dbSNP
rs1257652052 787 dbSNP
rs1201544294 795 dbSNP
rs11556590 798 dbSNP
rs1258366100 802 dbSNP
rs193214340 807 dbSNP
rs1381423782 827 dbSNP
rs771065057 834 dbSNP
rs1267677792 835 dbSNP
rs937601945 837 dbSNP
rs1057260666 845 dbSNP
rs16989707 867 dbSNP
rs895968862 873 dbSNP
rs751134159 875 dbSNP
rs1450931826 877 dbSNP
rs1405792890 879 dbSNP
rs1326819858 892 dbSNP
rs776760285 893 dbSNP
rs994380080 908 dbSNP
rs1463700944 916 dbSNP
rs762848177 920 dbSNP
rs1210309502 950 dbSNP
rs1169863962 951 dbSNP
rs1047575158 962 dbSNP
rs1441811895 963 dbSNP
rs759030637 967 dbSNP
rs1238766306 978 dbSNP
rs184726509 987 dbSNP
rs1460762270 991 dbSNP
rs1475217925 993 dbSNP
rs1200199375 1000 dbSNP
rs1479468786 1032 dbSNP
rs13731 1047 dbSNP
rs1244891105 1060 dbSNP
rs1005530461 1074 dbSNP
rs146220578 1077 dbSNP
rs757675577 1091 dbSNP
rs1382565034 1095 dbSNP
rs981389107 1130 dbSNP
rs767290538 1135 dbSNP
rs750029393 1136 dbSNP
rs996093375 1137 dbSNP
rs1030284558 1175 dbSNP
rs1332755611 1186 dbSNP
rs1190831817 1188 dbSNP
rs1161643124 1190 dbSNP
rs1377367472 1194 dbSNP
rs1380790468 1203 dbSNP
rs755819663 1231 dbSNP
rs1287990302 1252 dbSNP
rs1348919530 1307 dbSNP
rs1249401479 1315 dbSNP
rs1210049858 1322 dbSNP
rs954690998 1323 dbSNP
rs988685892 1341 dbSNP
rs1359391336 1345 dbSNP
rs1241415666 1347 dbSNP
rs912949691 1348 dbSNP
rs750674335 1355 dbSNP
rs1334333870 1361 dbSNP
rs1417295828 1361 dbSNP
rs1344020703 1373 dbSNP
rs1198679078 1375 dbSNP
rs1306638263 1388 dbSNP
rs1387530579 1391 dbSNP
rs1367586175 1400 dbSNP
rs11556592 1419 dbSNP
rs11556593 1424 dbSNP
rs1280567730 1428 dbSNP
rs1424056148 1444 dbSNP
rs188822868 1452 dbSNP
rs1160170099 1457 dbSNP
rs753362922 1479 dbSNP
rs926963456 1485 dbSNP
rs1058262 1494 dbSNP
rs937047399 1501 dbSNP
rs1057502611 1504 dbSNP
rs1266274984 1505 dbSNP
rs779430175 1525 dbSNP
rs1488297130 1528 dbSNP
rs780420406 1529 dbSNP
rs1483852608 1534 dbSNP
rs1182073242 1537 dbSNP
rs1285642516 1540 dbSNP
rs111982768 1542 dbSNP
rs113666438 1549 dbSNP
rs1207400545 1563 dbSNP
rs1349030070 1571 dbSNP
rs1260484913 1582 dbSNP
rs1234365389 1589 dbSNP
rs1347658415 1604 dbSNP
rs1281542815 1607 dbSNP
rs192153580 1629 dbSNP
rs1404428433 1639 dbSNP
rs1364794566 1645 dbSNP
rs1320286292 1652 dbSNP
rs113220868 1665 dbSNP
rs917534807 1672 dbSNP
rs1172975160 1675 dbSNP
rs1470794490 1680 dbSNP
rs184455328 1682 dbSNP
rs1047243373 1703 dbSNP
rs1477898741 1713 dbSNP
rs1243311517 1719 dbSNP
rs1196013690 1734 dbSNP
rs1435861782 1735 dbSNP
rs1445801152 1737 dbSNP
rs1261596394 1739 dbSNP
rs1204718630 1742 dbSNP
rs1326028299 1751 dbSNP
rs1261565644 1752 dbSNP
rs146012514 1756 dbSNP
rs1005643668 1757 dbSNP
rs1428673339 1772 dbSNP
rs1364234565 1773 dbSNP
rs1039852243 1777 dbSNP
rs1393420557 1788 dbSNP
rs189757153 1808 dbSNP
rs757747484 1816 dbSNP
rs1454426074 1819 dbSNP
rs998228639 1826 dbSNP
rs1175310207 1835 dbSNP
rs139621659 1848 dbSNP
rs762443871 1870 dbSNP
rs1421146137 1880 dbSNP
rs1165687473 1896 dbSNP
rs1305560054 1899 dbSNP
rs745919363 1903 dbSNP
rs746186508 1909 dbSNP
rs768498208 1912 dbSNP
rs1241652943 1913 dbSNP
rs1462989359 1913 dbSNP
rs1203330529 1917 dbSNP
rs1438638650 1924 dbSNP
rs13138 1930 dbSNP
rs1227529233 1939 dbSNP
rs181442924 1941 dbSNP
rs890397124 1946 dbSNP
rs1271939831 1950 dbSNP
rs1248036150 1959 dbSNP
rs1335862096 1971 dbSNP
rs1447201207 1974 dbSNP
rs561162122 1985 dbSNP
rs1010457172 2002 dbSNP
rs1196031076 2003 dbSNP
rs1408924199 2029 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugcagucacugacgcGGGGGa 5'
                          ||||| 
Target 5' ----------------CCCCCa 3'
 		1 - 6
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_002444 | 3UTR | AAUGUAGCCAUGGGACCAAACCUAGCCCCUUAGCCCCCACCCACUUCCCUGGGCAAAUGAAUGGCUCACUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_002444 | 3UTR | CCCCCACCCACUUCCCUGGGCAAAUGAAUGGCUCACUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_002444 | 3UTR | UUAGCCCCCACCCACUUCCCUGGGCAAAUGAAUGGCUCACUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_002444 | 3UTR | UAGCCCCCACCCACUUCCCUGGGCAAAUGAAUGGCUCACUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000360270.5 | 3UTR | CCCCCACCCACUUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
67 hsa-miR-4697-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT441332 C19orf26 CACN beta subunit associated regulatory protein 2 4
MIRT451390 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT452310 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT455043 MEN1 menin 1 2 2
MIRT455256 DDX39B DExD-box helicase 39B 2 10
MIRT461279 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 2
MIRT464945 TXLNA taxilin alpha 2 4
MIRT468043 SIK1 salt inducible kinase 1 2 2
MIRT472523 NACC1 nucleus accumbens associated 1 2 2
MIRT472929 MSN moesin 2 2
MIRT473247 MIDN midnolin 2 2
MIRT475828 HDGF heparin binding growth factor 2 2
MIRT478744 CS citrate synthase 2 2
MIRT480081 CALR calreticulin 2 2
MIRT483482 STMN3 stathmin 3 2 4
MIRT483643 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT483721 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT484539 BARHL1 BarH like homeobox 1 2 6
MIRT486041 WSCD1 WSC domain containing 1 2 4
MIRT486142 SIX5 SIX homeobox 5 2 6
MIRT486498 MYH11 myosin heavy chain 11 2 2
MIRT486977 STEAP3 STEAP3 metalloreductase 2 4
MIRT487279 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 4
MIRT487742 MIB2 mindbomb E3 ubiquitin protein ligase 2 2 2
MIRT487987 RXRB retinoid X receptor beta 2 2
MIRT488338 PAX2 paired box 2 2 2
MIRT488668 WWP2 WW domain containing E3 ubiquitin protein ligase 2 2 4
MIRT488752 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488812 TBC1D28 TBC1 domain family member 28 2 2
MIRT489380 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT489744 TACC3 transforming acidic coiled-coil containing protein 3 2 2
MIRT489960 GNB2 G protein subunit beta 2 2 2
MIRT490418 VPS51 VPS51, GARP complex subunit 2 4
MIRT490639 FEM1A fem-1 homolog A 2 2
MIRT491086 MSI1 musashi RNA binding protein 1 2 4
MIRT491298 VGF VGF nerve growth factor inducible 2 4
MIRT491366 SLC12A5 solute carrier family 12 member 5 2 2
MIRT492464 RASD1 ras related dexamethasone induced 1 2 4
MIRT492872 NFIX nuclear factor I X 2 2
MIRT492951 NEUROD2 neuronal differentiation 2 2 2
MIRT493704 H2AFX H2A histone family member X 2 2
MIRT493977 EIF1 eukaryotic translation initiation factor 1 2 4
MIRT500360 ZNF385A zinc finger protein 385A 2 2
MIRT501154 SLC10A7 solute carrier family 10 member 7 2 6
MIRT509625 RRP7A ribosomal RNA processing 7 homolog A 2 4
MIRT512232 ATG2A autophagy related 2A 2 8
MIRT529822 ARGFX arginine-fifty homeobox 2 4
MIRT531179 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT538971 BCL7A BCL tumor suppressor 7A 2 2
MIRT548357 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 4
MIRT553634 TJAP1 tight junction associated protein 1 2 2
MIRT558050 EVI5L ecotropic viral integration site 5 like 2 2
MIRT562548 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT568941 RUNX3 runt related transcription factor 3 2 2
MIRT569114 ONECUT3 one cut homeobox 3 2 2
MIRT573591 CERS1 ceramide synthase 1 2 2
MIRT619317 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT621202 ARPC1B actin related protein 2/3 complex subunit 1B 2 2
MIRT628844 FAM151B family with sequence similarity 151 member B 2 2
MIRT670497 LYRM4 LYR motif containing 4 2 2
MIRT670545 SHISA2 shisa family member 2 2 2
MIRT671026 PCDHB2 protocadherin beta 2 2 2
MIRT688989 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT709275 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT715084 ELOF1 elongation factor 1 homolog 2 2
MIRT718348 NPBWR1 neuropeptides B and W receptor 1 2 2
MIRT737406 MMP7 matrix metallopeptidase 7 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4697 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-4697-5p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4697-5p Paclitaxel 36314 NSC125973 approved resistant High Breast Cancer cell line (Bads-200, Bats-72, BCap37)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (total RNA)
hsa-miR-4697-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-4697-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4697-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4697-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4697-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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