pre-miRNA Information | |
---|---|
pre-miRNA | hsa-mir-4480 |
Genomic Coordinates | chr10: 12578753 - 12578823 |
Description | Homo sapiens miR-4480 stem-loop |
Comment | None |
RNA Secondary Structure | ![]() |
Mature miRNA Information | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mature miRNA | hsa-miR-4480 | |||||||||||||||||||||
Sequence | 44| AGCCAAGUGGAAGUUACUUUA |64 | |||||||||||||||||||||
Evidence | Experimental | |||||||||||||||||||||
Experiments | Illumina | |||||||||||||||||||||
Editing Events in miRNAs |
|
|||||||||||||||||||||
SNPs in miRNA |
|
|||||||||||||||||||||
Putative Targets |
Gene Information | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene Symbol | MAFK | ||||||||||||||||||||
Synonyms | NFE2U, P18 | ||||||||||||||||||||
Description | MAF bZIP transcription factor K | ||||||||||||||||||||
Transcript | NM_002360 | ||||||||||||||||||||
Expression | |||||||||||||||||||||
Putative miRNA Targets on MAFK | |||||||||||||||||||||
3'UTR of MAFK (miRNA target sites are highlighted) |
>MAFK|NM_002360|3'UTR 1 TGCCGGCCGGGGGCGGGGGGTGGCGGGCGGCGGGCGGCGGGCAGGCGGGTGGGGGCACACCCCTCGTACCTGTCACTGGG 81 ATGCAGACTCTCGACATCCGAGTCCAAGCGCAGGCCCCTCGGGCGCAGGCAGCTCACACCAGGAAGAGACTGTATTGCAG 161 GGTGAAGAGTGGGCTCCCGTGGGCCCAGAGCTGCACGCCGGTCCACAGACACACTCACGCCCGCCACCTGCTCCCCGCAG 241 GATGTGTCTGTGTGTGGGAATTGGTATCTTGCACCCGTGGGAGTCGGGACATATAATGGAAAGGCCCTCGGGAAGTTCCG 321 CGTCCTCTGTGGGGGCTGCCGGAAGACACGGCCCCAGGAGTCAGGCCCCTGTGGTCAGGTCTAGCATGGGGCTTGTTTTC 401 CACTCCTGCTGTAAGCAGCCTTCGACACCTGTCCTGCCACGGCCTCCCAGCCGGTGCGGGAGCCCCTCACTGCCCTGACC 481 GACTCCGCAGTCCCCGGGGAGGAGCATGGATGGTGTGTCGGCAGCTCCGTCCTTCCAGCTGTCCCGTTGCAGTGCCCGTG 561 ATCCGCGTCTGCCTTAGCAGGGGCCTGCGTGAGTGGGCACGGTGTGGGAGGTCGCCTGCGTGGGGTGGTGTCTGTGTGTG 641 TGCACGCACGCCTGCCATCAAAGCAGCAGGGCTGAGGGGGTGCAGCTTGCTGGTGTTCACTGGGGGAGGGCCTGTGGGCA 721 CACATGGCAGAGAGAGTGGCTCACACGTCGTGAGGTCTCCCCTGTGCTCTGGTGACCCGAGGAGGTCGTGCAGCACAGCG 801 CAGAAGCCCCTGCCCACGGGATCCGGCCCCCCAGACACCGACCCCACAGGCCGTCCCGGATCTCAGCGGACACAGGCAGG 881 AGCGCCCCATCATTTGACGGTGAGCAGGACTCAGGCTGTGTGTCCTGGAGCTACTTCTCACCAACTGTGGTCAGTGCAGG 961 GGGAACGAGGAGGTCTTTTGGGGGCCTGGCGAGGGGAAGGGCTGCTGCAGTCTAGGGAGAGGGGGTGCAGCCTGGGGGAT 1041 GTTGGTGGACATGGATGTGGAGGTGGAAGGAGGAGGACGTTGCGTGGAGTGGTGGGAGGAGGCGGGAGCCGTGTGCGAGA 1121 GCAGGTGGAAAGCCTTGAGGGGCAGGACCAGGATGCAGCTGGCTTGTAGAAGAGCTCAGGAGTGAGCCTGGCACTCCAGA 1201 GGGCGCGGCGGGTGGGGAGGCAGCAGGCACCAGTCCAGGAGAGCTTCGTGGACGTGGCTCCTGCGCGCACACCCCCAGGA 1281 GCACAGCCACGGGCTGCAGGTGTGGCTGGCCTCAGCACTCAGTCCTCACCCGGAGCCTTTGCCTGCTCCTCCTTCCAAGA 1361 GCACTGAGGCACCAGTGGGCTTGGCACTCCACCTTGGGCTTCCTTTTCCTGGAGAGCCGCCTTGAGGGTCCCTCCTGTGA 1441 CTGGGGTCTCTGCAGCGAGAGCCGCGGGGGTTGCGGAGCCCCTGCCTGGGGGAGCTGGCGGAATGTGAGCCGCCGGCCGG 1521 GGGCCGCCACATAAGACCTGCAAGGTGGTGCCTGGGGCCCTGGCTCCTTCTCGGCTGCCCCTGCCCACCCAGTAACAGCC 1601 CCCACCAGCTACAGAGCCCAGGCGGGTGCCAGCCACGCTGGGAGGGCAGAGGACAGACAGCCCCGGGGCTGCGACTTGGT 1681 TCTGTGTCTACTGTTAGAAGTTGAGTGGGAAGCTGCAGGCCCGCCAGGACCACTGGGTCCCTACAGAGCAAAGGCCTGCG 1761 TGTTCCCAAACAGCCGTTGCCCCCGTGGCCGTGGTAGGTAATCCATATTGGATGTCATAAGGACCAGGGGGATATTTAAA 1841 GAGAGAAACAGAAAATATATAGAGATATAAAATTATATTCACAGTTTATCTACAGATTTTTCGTAACAATCTTTCTTTTC 1921 CAGTTTGATACTGTAAATCTATCAGAGCAGAGCCGGGGGCACGGGCACAGGTGGGAGTTGGGAGCAAAGCGGAGGCCCGG 2001 GCTGCCCGCCGTCCCCCTTCATCTCCCCACGGACTGTACCAGGCAGCTGGGCCCCGCAGGACAGGCCGCAGCGGGTGGCC 2081 GGTTCTGTCCCGTCTTGGGGTTCTTGGTGTCCACGTCTTGTGGGCCGTGGGCTTCTACCTGCCCTTGGCCTGCAGTGCTT 2161 TGCTGGAGAAGGGACTCCCTGGTCCCCAGGGTGGACGGAGCCGCTGTCACCGCCCAGAGCTGGGCCGGGGAAGCACGGTG 2241 TGTTCTGCTTTTCTTTTCAGATTGTTGAAATTTCATTGTCATGATTTAATATATGGATTTTTTTATTTAAGAAAAAGACG 2321 AGGGACTCTTTGTCACGTGGGTTTGTTTTCTGTCTCCGTGCCTCCGGCTTCCCAAAGAGATCCAGGTCTTTGCGTTTCCA 2401 GGGCGTGGGGACCCCGGCCCCCTATGCCGCCACGCCGCCACACCGCCTCACCCTGGCTTCTGTGCTACTTGGCAGTTCCA 2481 TTTCATTATTTATTTTTTGTGCTGCTTTTTATCATGATATAAATTATTGAAAACAGATCACATGTGGGCCCGTGTCTGGC 2561 CGCCGCCGCCCTGCCCCGTCCCTGCGGCCACCACCTAATTTATTGCCGTGCGTCCTGCTGCTGTGACTGCTTTTGTACCT 2641 TTGCAATAAAGAATTTTCTGGTTTCAGA Target sites
Provided by authors
Predicted by miRanda
DRVs
SNPs
DRVs & SNPs
|
||||||||||||||||||||
miRNA-target interactions (Predicted by miRanda) |
|
||||||||||||||||||||
DRVs in gene 3'UTRs | |||||||||||||||||||||
SNPs in gene 3'UTRs |
Experimental Support 1 for Functional miRNA-Target Interaction | |||||||
---|---|---|---|---|---|---|---|
miRNA:Target | ---- | ||||||
Validation Method |
|
||||||
Conditions | HEK293 | ||||||
Location of target site | 3'UTR | ||||||
Tools used in this research | TargetScan , miRTarCLIP , Piranha | ||||||
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection
... - Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell. |
||||||
miRNA-target interactions (Provided by authors) |
|
||||||
Article |
- Hafner M; Landthaler M; Burger L; Khorshid et al. - Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
|
Experimental Support 2 for Functional miRNA-Target Interaction | |||||||
---|---|---|---|---|---|---|---|
miRNA:Target | ---- | ||||||
Validation Method |
|
||||||
Conditions | TZM-bl | ||||||
Location of target site | 3'UTR | ||||||
Tools used in this research | TargetScan , miRTarCLIP , Piranha | ||||||
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL
... - Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio. |
||||||
miRNA-target interactions (Provided by authors) |
|
||||||
Article |
- Whisnant AW; Bogerd HP; Flores O; Ho P; et al. - mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
|
Experimental Support 3 for Functional miRNA-Target Interaction | |
---|---|
miRNA:Target | ---- |
Validation Method |
|
Conditions | MCF7 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated
... - Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology. |
Article |
- Farazi TA; Ten Hoeve JJ; Brown M; et al. - Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
|
Experimental Support 4 for Functional miRNA-Target Interaction | |
---|---|
miRNA:Target | ---- |
Validation Method |
|
Conditions | HCT116 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in ERX177624. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_4_2
PAR-CLIP data was present in ERX177610. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_2_12
... - Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research. |
Article |
- Krell J; Stebbing J; Carissimi C; Dabrowska et al. - Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
|
CLIP-seq Support 1 for dataset GSM545217 | |
---|---|
Method / RBP | PAR-CLIP / AGO2 |
Cell line / Condition | HEK293 / miR-7 transfection |
Location of target site | ENST00000343242.4 | 3UTR | CACUCCACCUUGGGCUUCCUUUUCCU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 2 for dataset SRR1045082 | |
---|---|
Method / RBP | PAR-CLIP / AGO2 |
Cell line / Condition | MCF7 / Untreated |
Location of target site | ENST00000343242.4 | 3UTR | CACUCCACCUUGGGCUUCCUUUUCCUG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 24398324 / SRX388831 |
CLIP-seq Viewer | Link |
CLIP-seq Support 3 for dataset GSM1462574 | |
---|---|
Method / RBP | PAR-CLIP / AGO2 |
Cell line / Condition | TZM-bl / TZM-bl ami BaL |
Location of target site | ENST00000343242.4 | 3UTR | CACUCCACCUUGGGCUUCCUUUUCCUG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23592263 / GSE59944 |
CLIP-seq Viewer | Link |
MiRNA-Target Expression Profile | |||||||
---|---|---|---|---|---|---|---|
|
MiRNA-Target Expression Profile (TCGA) | |||||||
---|---|---|---|---|---|---|---|
|
117 hsa-miR-4480 Target Genes:
Functional analysis:
ID![]() |
Target | Description | Validation methods |
![]() |
![]() |
|||||||
Strong evidence | Less strong evidence | |||||||||||
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
|||||
MIRT056040 | MLLT10 | MLLT10, histone lysine methyltransferase DOT1L cofactor | ![]() |
![]() |
2 | 2 | ||||||
MIRT091259 | FXR1 | FMR1 autosomal homolog 1 | ![]() |
![]() |
2 | 4 | ||||||
MIRT117347 | MAPRE2 | microtubule associated protein RP/EB family member 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT234960 | ZNF439 | zinc finger protein 439 | ![]() |
![]() |
2 | 4 | ||||||
MIRT441356 | ZNF75A | zinc finger protein 75a | ![]() |
![]() |
2 | 2 | ||||||
MIRT441426 | STXBP2 | syntaxin binding protein 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441455 | ZNF488 | zinc finger protein 488 | ![]() |
![]() |
2 | 4 | ||||||
MIRT441524 | ZBTB10 | zinc finger and BTB domain containing 10 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441576 | EXOC5 | exocyst complex component 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441597 | ABCB5 | ATP binding cassette subfamily B member 5 | ![]() |
![]() |
2 | 6 | ||||||
MIRT441610 | ATP13A4 | ATPase 13A4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441698 | CIT | citron rho-interacting serine/threonine kinase | ![]() |
![]() |
2 | 2 | ||||||
MIRT441714 | FGF9 | fibroblast growth factor 9 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441784 | MAPK8 | mitogen-activated protein kinase 8 | ![]() |
![]() |
2 | 4 | ||||||
MIRT441795 | EXOSC2 | exosome component 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441868 | RNASEL | ribonuclease L | ![]() |
![]() |
2 | 2 | ||||||
MIRT441900 | SLC9A8 | solute carrier family 9 member A8 | ![]() |
![]() |
2 | 6 | ||||||
MIRT441919 | FAM217B | family with sequence similarity 217 member B | ![]() |
![]() |
2 | 2 | ||||||
MIRT441928 | C1orf109 | chromosome 1 open reading frame 109 | ![]() |
![]() |
2 | 2 | ||||||
MIRT441938 | RIMKLB | ribosomal modification protein rimK like family member B | ![]() |
![]() |
2 | 2 | ||||||
MIRT442157 | DPY19L1 | dpy-19 like C-mannosyltransferase 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442172 | AZF1 | azoospermia factor 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442208 | IRS1 | insulin receptor substrate 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442237 | DDX19A | DEAD-box helicase 19A | ![]() |
![]() |
2 | 2 | ||||||
MIRT442366 | ZC3HAV1L | zinc finger CCCH-type containing, antiviral 1 like | ![]() |
![]() |
2 | 2 | ||||||
MIRT442572 | SDC1 | syndecan 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442604 | ZNF391 | zinc finger protein 391 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442609 | MRC1 | mannose receptor C-type 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442647 | POP4 | POP4 homolog, ribonuclease P/MRP subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT442658 | OIP5 | Opa interacting protein 5 | ![]() |
![]() |
2 | 6 | ||||||
MIRT442686 | COX15 | COX15, cytochrome c oxidase assembly homolog | ![]() |
![]() |
2 | 2 | ||||||
MIRT442773 | JAG1 | jagged 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442785 | CHD8 | chromodomain helicase DNA binding protein 8 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442895 | PLCB3 | phospholipase C beta 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442941 | C17orf105 | chromosome 17 open reading frame 105 | ![]() |
![]() |
2 | 2 | ||||||
MIRT442959 | SGCD | sarcoglycan delta | ![]() |
![]() |
2 | 2 | ||||||
MIRT442998 | EDAR | ectodysplasin A receptor | ![]() |
![]() |
2 | 2 | ||||||
MIRT443017 | C21orf91 | chromosome 21 open reading frame 91 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443064 | CASP5 | caspase 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443069 | ABLIM1 | actin binding LIM protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443208 | VPS36 | vacuolar protein sorting 36 homolog | ![]() |
![]() |
2 | 2 | ||||||
MIRT443237 | ANKRD26 | ankyrin repeat domain 26 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443253 | A1CF | APOBEC1 complementation factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT443329 | JUN | Jun proto-oncogene, AP-1 transcription factor subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT443333 | NRAS | NRAS proto-oncogene, GTPase | ![]() |
![]() |
2 | 2 | ||||||
MIRT443349 | STX7 | syntaxin 7 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443452 | CLIC5 | chloride intracellular channel 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443547 | GPR35 | G protein-coupled receptor 35 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443616 | AVPR1A | arginine vasopressin receptor 1A | ![]() |
![]() |
2 | 2 | ||||||
MIRT443626 | CPSF2 | cleavage and polyadenylation specific factor 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443730 | ALPK3 | alpha kinase 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443786 | ST13 | ST13, Hsp70 interacting protein | ![]() |
![]() |
2 | 2 | ||||||
MIRT443852 | RGS6 | regulator of G protein signaling 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT445483 | KLF5 | Kruppel like factor 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT471105 | PHLDA2 | pleckstrin homology like domain family A member 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT472329 | NETO2 | neuropilin and tolloid like 2 | ![]() |
![]() |
2 | 4 | ||||||
MIRT472391 | NDRG3 | NDRG family member 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT473522 | MAX | MYC associated factor X | ![]() |
![]() |
2 | 2 | ||||||
MIRT473874 | MAFK | MAF bZIP transcription factor K | ![]() |
![]() |
2 | 6 | ||||||
MIRT476021 | GTF2A1 | general transcription factor IIA subunit 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT478320 | DDN | dendrin | ![]() |
![]() |
2 | 2 | ||||||
MIRT492049 | TNFSF9 | TNF superfamily member 9 | ![]() |
![]() |
2 | 2 | ||||||
MIRT494851 | ANKRD24 | ankyrin repeat domain 24 | ![]() |
![]() |
2 | 2 | ||||||
MIRT494991 | TSSC1 | EARP complex and GARP complex interacting protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495034 | RASSF2 | Ras association domain family member 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495111 | NOL10 | nucleolar protein 10 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495113 | TRADD | TNFRSF1A associated via death domain | ![]() |
![]() |
2 | 2 | ||||||
MIRT495131 | METTL24 | methyltransferase like 24 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495147 | STAC2 | SH3 and cysteine rich domain 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495297 | NUP54 | nucleoporin 54 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495341 | RTN2 | reticulon 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495347 | ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) | ![]() |
![]() |
2 | 2 | ||||||
MIRT496682 | DUSP18 | dual specificity phosphatase 18 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496743 | TGFBR1 | transforming growth factor beta receptor 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496841 | KCNIP2 | potassium voltage-gated channel interacting protein 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496852 | GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | ![]() |
![]() |
2 | 2 | ||||||
MIRT496889 | FOXP1 | forkhead box P1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496922 | CLMN | calmin | ![]() |
![]() |
2 | 2 | ||||||
MIRT496990 | TMEM231 | transmembrane protein 231 | ![]() |
![]() |
2 | 2 | ||||||
MIRT497002 | SNAP25 | synaptosome associated protein 25 | ![]() |
![]() |
2 | 2 | ||||||
MIRT497058 | C6orf223 | chromosome 6 open reading frame 223 | ![]() |
![]() |
2 | 2 | ||||||
MIRT500529 | YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | ![]() |
![]() |
2 | 6 | ||||||
MIRT506048 | PPP6C | protein phosphatase 6 catalytic subunit | ![]() |
![]() |
2 | 4 | ||||||
MIRT512163 | CD164 | CD164 molecule | ![]() |
![]() |
2 | 6 | ||||||
MIRT527051 | RDH13 | retinol dehydrogenase 13 | ![]() |
![]() |
2 | 2 | ||||||
MIRT532282 | TNFSF14 | TNF superfamily member 14 | ![]() |
![]() |
2 | 2 | ||||||
MIRT534083 | SPRY4 | sprouty RTK signaling antagonist 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT534605 | RNASEH1 | ribonuclease H1 | ![]() |
![]() |
2 | 4 | ||||||
MIRT539509 | ACSS3 | acyl-CoA synthetase short chain family member 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT543069 | ARID4B | AT-rich interaction domain 4B | ![]() |
![]() |
2 | 2 | ||||||
MIRT544233 | CCBL2 | kynurenine aminotransferase 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT544686 | ZNF224 | zinc finger protein 224 | ![]() |
![]() |
2 | 4 | ||||||
MIRT546269 | TMEM30A | transmembrane protein 30A | ![]() |
![]() |
2 | 4 | ||||||
MIRT559069 | C19orf47 | chromosome 19 open reading frame 47 | ![]() |
![]() |
2 | 2 | ||||||
MIRT562768 | RMI2 | RecQ mediated genome instability 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT563974 | HCFC1 | host cell factor C1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT564086 | NSA2 | NSA2, ribosome biogenesis homolog | ![]() |
![]() |
2 | 2 | ||||||
MIRT564525 | PDXP | pyridoxal phosphatase | ![]() |
![]() |
2 | 2 | ||||||
MIRT564613 | ZNF703 | zinc finger protein 703 | ![]() |
![]() |
2 | 2 | ||||||
MIRT566252 | PTBP1 | polypyrimidine tract binding protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT614420 | ZNF440 | zinc finger protein 440 | ![]() |
![]() |
2 | 2 | ||||||
MIRT618789 | MTHFR | methylenetetrahydrofolate reductase | ![]() |
![]() |
2 | 2 | ||||||
MIRT619160 | PPDPF | pancreatic progenitor cell differentiation and proliferation factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT641778 | ZDHHC7 | zinc finger DHHC-type containing 7 | ![]() |
![]() |
2 | 4 | ||||||
MIRT653680 | SLC25A36 | solute carrier family 25 member 36 | ![]() |
![]() |
2 | 2 | ||||||
MIRT657861 | GJD2 | gap junction protein delta 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT660879 | ADCYAP1R1 | ADCYAP receptor type I | ![]() |
![]() |
2 | 2 | ||||||
MIRT668781 | DAAM1 | dishevelled associated activator of morphogenesis 1 | ![]() |
![]() |
2 | 4 | ||||||
MIRT688559 | DCAF16 | DDB1 and CUL4 associated factor 16 | ![]() |
![]() |
2 | 2 | ||||||
MIRT695393 | WDR41 | WD repeat domain 41 | ![]() |
![]() |
2 | 2 | ||||||
MIRT698680 | TCEA1 | transcription elongation factor A1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT700974 | PDIA6 | protein disulfide isomerase family A member 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT705055 | C5orf15 | chromosome 5 open reading frame 15 | ![]() |
![]() |
2 | 2 | ||||||
MIRT705864 | AFF1 | AF4/FMR2 family member 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT710586 | CDCA4 | cell division cycle associated 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT713904 | IGF2R | insulin like growth factor 2 receptor | ![]() |
![]() |
2 | 2 | ||||||
MIRT717133 | SKI | SKI proto-oncogene | ![]() |
![]() |
2 | 2 |
miRNA-Drug Associations | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
miRNA-Drug Resistance Associations | ||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|