miRTarBase - #MIRT474905


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pre-miRNA Information
pre-miRNA hsa-let-7e   
Genomic Coordinates chr19: 51692786 - 51692864
Synonyms MIRNLET7E, hsa-let-7e, let-7e, MIRLET7E
Description Homo sapiens let-7e stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7e-5p
Sequence 8| UGAGGUAGGAGGUUGUAUAGUU |29
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1189776118 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KCTD21   
Synonyms KCASH2
Description potassium channel tetramerization domain containing 21
Transcript NM_001029859   
Expression
Putative miRNA Targets on KCTD21
3'UTR of KCTD21
(miRNA target sites are highlighted)		 
>KCTD21|NM_001029859|3'UTR
   1 AAGGACCCCAACAACACTGGAGATGGGGAGTCCCAGGAAGCTCATGTCAGCCAGGTCTTGGAGGGCATCTCGCCAGTGGT
  81 GCGAGGCAGGGGACTATACTAATCTGTATTAATTGTGTAGCAGGACTTGATTCCCCCCATGATGAAGTCCACCTTTTGGA
 161 ATCCAGTGTCCTCTGAACAGAACCACCTTTTTTCTTGCCATTTTGAGCTGCAGACAGGCGGTTTATTATGACAAGTGAAG
 241 AGTCAGCTGATGTGTACTAAAGGAGGCCATAGGAGGATTTTCCAGCCAGGACAAAAGAGCAGCAGTTTTCTCCTGGGCTC
 321 CATCTCTCTGTACCGCTAGCCAGTGCCGCATTTATCCATCTGTAAGAAGGCCCTGGTGGAGAGGATGGGATGAGAACAAG
 401 AGGCTACCTCCAGTTAACCAGGACATAAAGTCCCCAGCGGTTCCTGTCACACCTGCTCCTCCCTCCCCAGGGTGCATCCA
 481 TGATCGTGGATGTTTGCCCAGGGGTGACCATGTTTGGCTGGCTTGGAATGCTGTGCATTCTCAGAGCTCTGTTAGTGTCC
 561 CCTCTTGGGGGTCAGAGATGAGGTGTGGCAGGGTCTAGAGGAATGAGTGTCCAGGCAGAGTTCAGAAGGTAGGAATGTCC
 641 CTCTTGATAGGGCTGAATCAAGGGATTCCTGGCTTTAGAAAGGGTCTGCTATCTTTGCAAAAATGTGCAAGTATCTGTAG
 721 CCAGTGTAATGAAATCACTTCCAAATCCAGCCTGTTACCTGACTTTTGTCATTGTTTTCCCAAAAATTTGAGGTATCATT
 801 GAAACAGGTCATTTTAAACAAATCTATTACGGATTCTCAGGGTTGGAAATAATTCGATGATTGCTTAGTCCTCCCCCACC
 881 CCTAGAACACCCCAGCACATCTGAAGATGAGCGCCTCTCCCTGGGTACCTGCAAGTGATCACCTTGGCCTGCTTGCATAC
 961 CTTGGCTGATAGGAAGCGCGCCATCCCCAAGGCAGCTCCTGCTGTGGTTGGACAGTGCTGACTGTTAGACAGTTCTTCCC
1041 TATATTGAGCCAAAATCTGTCCTGCCACTTGCTGGATCTTGGTTGCAGACCTTCCCATTCACCCAGTTATATATCTTTGC
1121 TTTCAAAATAGTCACCTTGAGAGACCAGACATTTTTCTGAAAACATCATTACTCAGAATTCAGATTCCCCTCTGGGATCT
1201 GTCTTCAGAATCAAAGTTAGCTCTTTTCTATCCCCTGTAAGTCAGTCCCCTTTTGTTGTAGCTTCACCTCGTTTGTGACC
1281 CCCACTTCACCCACCTTCCCCACCATCTGTGGCTCCATATACCTTTCGACCATTTTCTGCTGGAAGAGGAAGATTCACGG
1361 CCCCTGAGGAGATCCAGAGGAAAGAGACGGTCTCCAAGGGTGCTGTGCAGCAAGGAGCCCAGGAGTGGTATGAACCGTAA
1441 CAGTGCCCTTAGAGTAAATGTGCGGCCCCTAAGACCCTGCCCTCAGGAAGGCGGCCTTCCCCTGCAGTCCTGTGTCCCAC
1521 CCCTGGGTCTCTGTAGGGTGCCATCCAGGGCAAGCAACCCAAGCACTGCTTCCCACCGGGTGATGAGCCATGCAGGCCTC
1601 CAAACTGCACGTCATGATTCATCCCTAAAGTGAGTTTGGCCTTGAGAGTCCCCAGGGTCCTCCCCCACTGGGCAGGGGTC
1681 CTCAAAGCCAAGGAAGCCTGGTGACACAGGCACCCATGGGAGGTGGGCCCAGAAAGGGGCTTCCCATAGATAGGCCCTGT
1761 GAGTAGGGAGCTTGTACACTGGGCCATGGGCAGCGCCAGTTCCCTTGAGCAGTAAAGGCCCTTTTCCCCCTACGGTGGGA
1841 CCCAGGAGTCTCTCTGACAGCTTTTCTGCCAGGCACAGTGGCTCATGCCTGTAATCCCAACACTCTGGGAGGCCGAGGCG
1921 GGAAGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACGTCGTCTCTGCTAAAAATACAAAAAT
2001 TAGCTGGGTGTGGTGACAGGCGCCTATAACCCCAGCTATTTGGGAGGCTGAGGCAGTAGAATCGCTTGAACCCAGATAGC
2081 AGAGGTTGCAGTGAGCTGAGAGTGTGCCATTGCAGAGAGACTCCATCCCAAAAAAAGACAGCTGTCCCAGGCCAAGGGTA
2161 CTTGGGAGAGCCCCTCATGGAGAACCTAGTTTAGACCAAGTAGCAGAAGCTGTGGTCATAACAAAACAATTTGAGGAAGA
2241 AATCTTACAAATCACCACTGCCCTTTCTCCTTTTCCATAAAACTGTCCATCTTTTCGGTGCTCCCTAATCCAAGCAGCTT
2321 GACTTTAGAGAAGTTGCAGAAGCAGTGAAGCCACTAACATGCTGTGTGACTTTATGCAAGTCACTCACCTCACTGAGCCA
2401 CCTCCATTTCTTCATCTGTGAAATAGGCATAACAGTAATACATAACCCTACCTACCTCACAGGGCTGTTGTGAGGATCAA
2481 ATGAAATAATGTAACGTGAGAATACAGTATAAATGATAAAGGATTGTT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uugAUAUGUU-GGA-GGAUGGAGu 5'
             || |:|| ||| |||||||| 
Target 5' taaTACATAACCCTACCTACCTCa 3'
 2436 - 2459 167.00 -21.70
2 
miRNA  3' uugauaUGUUGGAGGAUGGAGu 5'
                ||||    ||||||| 
Target 5' atgagaACAAGAGGCTACCTCc 3'
 390 - 411 148.00 -10.80
3 
miRNA  3' uuGAUA-UGUUG--GAGGAUGGAGu 5'
            ||:| ||| |  ||||| |||| 
Target 5' tcCTGTCACACCTGCTCCTCCCTCc 3'
 442 - 466 138.00 -15.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN1543545 4 COSMIC
COSN26981172 17 COSMIC
COSN30455586 27 COSMIC
COSN31512273 33 COSMIC
COSN8863614 36 COSMIC
COSN30522114 37 COSMIC
COSN30109191 42 COSMIC
COSN30123095 71 COSMIC
COSN16130527 72 COSMIC
COSN13352343 82 COSMIC
COSN8584765 86 COSMIC
COSN30110867 117 COSMIC
COSN30524030 124 COSMIC
COSN24303734 219 COSMIC
COSN27850445 607 COSMIC
COSN30166752 704 COSMIC
COSN28768188 830 COSMIC
COSN31589724 871 COSMIC
COSN7020295 968 COSMIC
COSN24656759 1085 COSMIC
COSN7020294 1346 COSMIC
COSN216965 1437 COSMIC
COSN25271332 1869 COSMIC
COSN31540991 2362 COSMIC
COSN31603634 2398 COSMIC
COSN28658421 2425 COSMIC
COSN23577190 2515 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs752867312 3 dbSNP
rs765435164 4 dbSNP
rs755490315 6 dbSNP
rs754380540 8 dbSNP
rs1387420904 10 dbSNP
rs766583173 11 dbSNP
rs761167201 13 dbSNP
rs773860364 14 dbSNP
rs972959546 17 dbSNP
rs763785078 18 dbSNP
rs1200205932 19 dbSNP
rs368809886 26 dbSNP
rs755258463 29 dbSNP
rs1431610228 30 dbSNP
rs762418147 32 dbSNP
rs867538587 33 dbSNP
rs230661 36 dbSNP
rs769308293 38 dbSNP
rs759404638 40 dbSNP
rs373870024 43 dbSNP
rs1264589562 45 dbSNP
rs761516895 47 dbSNP
rs776326346 48 dbSNP
rs1301101134 55 dbSNP
rs1364857991 57 dbSNP
rs1307673850 61 dbSNP
rs1284631121 71 dbSNP
rs576966487 72 dbSNP
rs1029861832 78 dbSNP
rs1028563876 82 dbSNP
rs553931929 83 dbSNP
rs998027602 87 dbSNP
rs147630167 92 dbSNP
rs1390269907 97 dbSNP
rs1293937673 99 dbSNP
rs1042295887 118 dbSNP
rs1417335308 123 dbSNP
rs946628229 126 dbSNP
rs1364561096 135 dbSNP
rs766493761 139 dbSNP
rs1054439737 141 dbSNP
rs1364801610 148 dbSNP
rs937367393 149 dbSNP
rs189052860 158 dbSNP
rs981971111 162 dbSNP
rs1390270583 171 dbSNP
rs1378199594 178 dbSNP
rs1158007163 188 dbSNP
rs1328989545 191 dbSNP
rs1337135623 194 dbSNP
rs1243384623 197 dbSNP
rs950203754 213 dbSNP
rs1040014683 214 dbSNP
rs554892177 219 dbSNP
rs776023118 220 dbSNP
rs538527358 221 dbSNP
rs1042249403 228 dbSNP
rs374705409 229 dbSNP
rs1444956648 232 dbSNP
rs1029375519 236 dbSNP
rs1371233496 239 dbSNP
rs772652812 257 dbSNP
rs902319501 267 dbSNP
rs1398089003 269 dbSNP
rs1485183168 270 dbSNP
rs534879786 283 dbSNP
rs184416123 290 dbSNP
rs879757591 291 dbSNP
rs1453785928 293 dbSNP
rs760657548 294 dbSNP
rs1216525272 297 dbSNP
rs1227415150 301 dbSNP
rs746384875 313 dbSNP
rs1320014092 315 dbSNP
rs1055080560 322 dbSNP
rs927973752 323 dbSNP
rs1461966463 326 dbSNP
rs937353949 329 dbSNP
rs532372828 334 dbSNP
rs117608617 335 dbSNP
rs1170978062 343 dbSNP
rs181042728 345 dbSNP
rs530165159 347 dbSNP
rs1406951839 348 dbSNP
rs1467305239 358 dbSNP
rs1358399643 360 dbSNP
rs1304948050 371 dbSNP
rs1297293665 374 dbSNP
rs1382019770 380 dbSNP
rs1420297134 383 dbSNP
rs112978408 385 dbSNP
rs541701212 398 dbSNP
rs910134381 402 dbSNP
rs986119977 409 dbSNP
rs1324517918 413 dbSNP
rs1020306829 419 dbSNP
rs997071399 421 dbSNP
rs953704415 425 dbSNP
rs1476597633 432 dbSNP
rs1259186358 435 dbSNP
rs531596707 438 dbSNP
rs965627988 439 dbSNP
rs1019036209 440 dbSNP
rs778007747 442 dbSNP
rs1198041954 443 dbSNP
rs902176845 452 dbSNP
rs1434539883 460 dbSNP
rs1216329342 463 dbSNP
rs529697922 465 dbSNP
rs1010647710 466 dbSNP
rs1362979661 468 dbSNP
rs1403696533 471 dbSNP
rs545756974 472 dbSNP
rs1054943184 479 dbSNP
rs530588 480 dbSNP
rs535504021 485 dbSNP
rs541216176 486 dbSNP
rs1216201287 487 dbSNP
rs1225600150 489 dbSNP
rs540309551 490 dbSNP
rs1221746536 491 dbSNP
rs908537161 500 dbSNP
rs1033559604 501 dbSNP
rs1002537892 504 dbSNP
rs984193464 506 dbSNP
rs905833542 508 dbSNP
rs1046128141 509 dbSNP
rs574630410 512 dbSNP
rs921445431 529 dbSNP
rs1332136721 530 dbSNP
rs1413795156 537 dbSNP
rs1402296400 543 dbSNP
rs1296563097 553 dbSNP
rs897240895 559 dbSNP
rs975520570 560 dbSNP
rs1241225863 561 dbSNP
rs966017902 578 dbSNP
rs1356924669 580 dbSNP
rs1019904954 581 dbSNP
rs1463786039 593 dbSNP
rs1453290689 600 dbSNP
rs999505681 606 dbSNP
rs966434562 609 dbSNP
rs1475959125 611 dbSNP
rs868594521 621 dbSNP
rs1020615965 627 dbSNP
rs1244155910 634 dbSNP
rs910061795 637 dbSNP
rs1049981921 641 dbSNP
rs932915953 644 dbSNP
rs867771411 646 dbSNP
rs1442293320 648 dbSNP
rs1257024428 651 dbSNP
rs1415116685 655 dbSNP
rs1010680452 668 dbSNP
rs1168405490 676 dbSNP
rs893532664 681 dbSNP
rs966399740 684 dbSNP
rs1333546339 691 dbSNP
rs1380888466 693 dbSNP
rs1451598479 697 dbSNP
rs913650866 703 dbSNP
rs17136321 704 dbSNP
rs1002080818 705 dbSNP
rs1212800767 705 dbSNP
rs1219422461 707 dbSNP
rs1200003550 712 dbSNP
rs906349225 714 dbSNP
rs1033942537 717 dbSNP
rs1260819867 719 dbSNP
rs1046336521 720 dbSNP
rs939913644 724 dbSNP
rs908567702 731 dbSNP
rs773795749 741 dbSNP
rs1048352213 751 dbSNP
rs1185221527 755 dbSNP
rs1474057836 755 dbSNP
rs1282143182 764 dbSNP
rs1447215706 765 dbSNP
rs1466166765 766 dbSNP
rs931404580 767 dbSNP
rs1338209099 770 dbSNP
rs538064594 772 dbSNP
rs1469530340 773 dbSNP
rs1334556898 779 dbSNP
rs189841855 786 dbSNP
rs1398860534 789 dbSNP
rs975901102 798 dbSNP
rs897167626 805 dbSNP
rs1422114402 807 dbSNP
rs1200744426 810 dbSNP
rs746006477 811 dbSNP
rs965608923 812 dbSNP
rs1280304434 819 dbSNP
rs1444432441 821 dbSNP
rs912708998 822 dbSNP
rs1037044391 826 dbSNP
rs977728299 828 dbSNP
rs7103718 830 dbSNP
rs538611908 831 dbSNP
rs1427361399 836 dbSNP
rs989105905 853 dbSNP
rs1480151814 854 dbSNP
rs566511233 855 dbSNP
rs1404643451 856 dbSNP
rs546637823 858 dbSNP
rs1050330942 859 dbSNP
rs1361063931 863 dbSNP
rs957687155 864 dbSNP
rs1439716084 869 dbSNP
rs1280801700 874 dbSNP
rs753323637 879 dbSNP
rs1033460947 881 dbSNP
rs1276203012 882 dbSNP
rs763793969 884 dbSNP
rs760419844 898 dbSNP
rs1222397414 899 dbSNP
rs1285820569 901 dbSNP
rs576989615 908 dbSNP
rs1025204778 912 dbSNP
rs779222802 913 dbSNP
rs1451055416 921 dbSNP
rs1199709624 923 dbSNP
rs913575656 924 dbSNP
rs1157767556 929 dbSNP
rs1380753861 932 dbSNP
rs1421294623 943 dbSNP
rs1301155436 945 dbSNP
rs1364911792 948 dbSNP
rs1004146076 950 dbSNP
rs1357014152 951 dbSNP
rs1333601922 953 dbSNP
rs536338610 955 dbSNP
rs989198977 958 dbSNP
rs1354789492 962 dbSNP
rs230662 963 dbSNP
rs548320918 966 dbSNP
rs926424957 969 dbSNP
rs767977930 970 dbSNP
rs531428355 971 dbSNP
rs562768611 972 dbSNP
rs931353932 973 dbSNP
rs552485936 977 dbSNP
rs970629321 978 dbSNP
rs1039819465 979 dbSNP
rs753941225 980 dbSNP
rs1444004125 987 dbSNP
rs1161478235 989 dbSNP
rs369908243 990 dbSNP
rs1458393244 994 dbSNP
rs944105282 995 dbSNP
rs1005533486 999 dbSNP
rs1331546359 1002 dbSNP
rs1378694129 1014 dbSNP
rs1449418700 1016 dbSNP
rs1347754969 1018 dbSNP
rs1246255219 1028 dbSNP
rs532478162 1028 dbSNP
rs1405121167 1029 dbSNP
rs1386197278 1032 dbSNP
rs1028441393 1038 dbSNP
rs560187042 1058 dbSNP
rs997420348 1060 dbSNP
rs1258911294 1064 dbSNP
rs1459292198 1083 dbSNP
rs1181506313 1086 dbSNP
rs901343602 1088 dbSNP
rs977966071 1097 dbSNP
rs1189455655 1099 dbSNP
rs184793098 1102 dbSNP
rs1371285372 1106 dbSNP
rs1438308232 1109 dbSNP
rs945622189 1110 dbSNP
rs574433787 1111 dbSNP
rs1401992131 1113 dbSNP
rs892112046 1119 dbSNP
rs1053429104 1120 dbSNP
rs560823251 1126 dbSNP
rs1471317763 1131 dbSNP
rs936386275 1155 dbSNP
rs191994039 1171 dbSNP
rs1490461216 1185 dbSNP
rs1293588911 1186 dbSNP
rs1218061539 1187 dbSNP
rs1278973058 1224 dbSNP
rs914865011 1227 dbSNP
rs575762029 1230 dbSNP
rs1307173079 1231 dbSNP
rs1483424964 1232 dbSNP
rs1201990943 1235 dbSNP
rs145317421 1241 dbSNP
rs1365113567 1247 dbSNP
rs538922904 1249 dbSNP
rs917772539 1250 dbSNP
rs971931809 1254 dbSNP
rs1436696476 1255 dbSNP
rs1466838732 1258 dbSNP
rs961919236 1259 dbSNP
rs778067804 1260 dbSNP
rs1399994167 1270 dbSNP
rs573243583 1271 dbSNP
rs984077334 1276 dbSNP
rs1221781898 1279 dbSNP
rs952782011 1281 dbSNP
rs1360441732 1282 dbSNP
rs1235111574 1284 dbSNP
rs980564628 1284 dbSNP
rs187574842 1285 dbSNP
rs1487918467 1288 dbSNP
rs1024816182 1290 dbSNP
rs1003961826 1295 dbSNP
rs996946294 1298 dbSNP
rs866639888 1299 dbSNP
rs1402499504 1305 dbSNP
rs1489610231 1305 dbSNP
rs1423090569 1306 dbSNP
rs1425394529 1324 dbSNP
rs536252690 1327 dbSNP
rs117114945 1328 dbSNP
rs1178674953 1330 dbSNP
rs527462 1340 dbSNP
rs1419490100 1349 dbSNP
rs1299286390 1353 dbSNP
rs1363033865 1354 dbSNP
rs1434353436 1354 dbSNP
rs537585897 1358 dbSNP
rs1270855741 1359 dbSNP
rs1191234261 1365 dbSNP
rs769935885 1366 dbSNP
rs1307350490 1368 dbSNP
rs1009760474 1371 dbSNP
rs892716255 1372 dbSNP
rs1261221702 1373 dbSNP
rs1217805967 1376 dbSNP
rs568938590 1388 dbSNP
rs748364410 1389 dbSNP
rs867749119 1391 dbSNP
rs899867598 1395 dbSNP
rs1040088836 1399 dbSNP
rs1175053193 1400 dbSNP
rs944151837 1402 dbSNP
rs891171543 1404 dbSNP
rs1237204524 1406 dbSNP
rs796497385 1411 dbSNP
rs184799633 1412 dbSNP
rs1159666196 1417 dbSNP
rs949181628 1418 dbSNP
rs781453420 1419 dbSNP
rs917690527 1421 dbSNP
rs758168648 1422 dbSNP
rs946229339 1424 dbSNP
rs1036141571 1426 dbSNP
rs532438336 1432 dbSNP
rs192456426 1436 dbSNP
rs117340236 1437 dbSNP
rs777206060 1439 dbSNP
rs114171467 1442 dbSNP
rs1376869539 1443 dbSNP
rs1227739701 1446 dbSNP
rs529678869 1447 dbSNP
rs1289990801 1448 dbSNP
rs561002158 1457 dbSNP
rs1322942235 1461 dbSNP
rs952787944 1463 dbSNP
rs543953901 1464 dbSNP
rs1455745371 1482 dbSNP
rs1240485546 1484 dbSNP
rs1472015814 1485 dbSNP
rs926322351 1493 dbSNP
rs1368184721 1495 dbSNP
rs1357515077 1508 dbSNP
rs921285993 1510 dbSNP
rs1168673074 1512 dbSNP
rs1399810079 1516 dbSNP
rs1470465385 1533 dbSNP
rs1431679868 1536 dbSNP
rs980810426 1540 dbSNP
rs965471334 1542 dbSNP
rs557349022 1544 dbSNP
rs1019738371 1546 dbSNP
rs1381295473 1554 dbSNP
rs970505055 1558 dbSNP
rs1277080152 1559 dbSNP
rs1318153479 1564 dbSNP
rs1200063046 1566 dbSNP
rs866376977 1574 dbSNP
rs1276079902 1575 dbSNP
rs535859275 1577 dbSNP
rs917699788 1578 dbSNP
rs575323240 1582 dbSNP
rs1238525412 1598 dbSNP
rs372399280 1610 dbSNP
rs867258963 1611 dbSNP
rs1423091446 1613 dbSNP
rs1203743721 1627 dbSNP
rs1478192922 1629 dbSNP
rs1009737742 1637 dbSNP
rs565130178 1640 dbSNP
rs1334621841 1658 dbSNP
rs1360810142 1660 dbSNP
rs767708506 1662 dbSNP
rs1026756954 1665 dbSNP
rs995404222 1666 dbSNP
rs768359966 1667 dbSNP
rs964277793 1672 dbSNP
rs1296667349 1676 dbSNP
rs904833599 1681 dbSNP
rs230663 1692 dbSNP
rs1215004426 1694 dbSNP
rs1462176413 1703 dbSNP
rs1488631944 1710 dbSNP
rs1195977597 1713 dbSNP
rs1245174854 1716 dbSNP
rs1477853971 1718 dbSNP
rs1172938201 1722 dbSNP
rs1426920974 1725 dbSNP
rs1008607567 1728 dbSNP
rs1013699157 1747 dbSNP
rs1157922253 1749 dbSNP
rs751123145 1754 dbSNP
rs1453448129 1756 dbSNP
rs1401271974 1758 dbSNP
rs1321065970 1761 dbSNP
rs573157789 1769 dbSNP
rs553276369 1778 dbSNP
rs940488605 1781 dbSNP
rs1350432898 1782 dbSNP
rs188906797 1783 dbSNP
rs1238461884 1789 dbSNP
rs1010305282 1794 dbSNP
rs148875580 1795 dbSNP
rs1206956252 1797 dbSNP
rs558572863 1806 dbSNP
rs762632024 1809 dbSNP
rs1049419888 1810 dbSNP
rs1172249876 1812 dbSNP
rs937584294 1818 dbSNP
rs1199776074 1819 dbSNP
rs1255149289 1820 dbSNP
rs557353990 1826 dbSNP
rs1380867012 1827 dbSNP
rs772702967 1832 dbSNP
rs1045977846 1833 dbSNP
rs949108170 1834 dbSNP
rs917579502 1845 dbSNP
rs1405430973 1846 dbSNP
rs1412936468 1847 dbSNP
rs931934021 1850 dbSNP
rs1308917747 1856 dbSNP
rs1378304530 1866 dbSNP
rs982520218 1868 dbSNP
rs1241897952 1870 dbSNP
rs1264192854 1891 dbSNP
rs1355795838 1900 dbSNP
rs182795465 1903 dbSNP
rs1275319470 1906 dbSNP
rs1462284542 1907 dbSNP
rs951111554 1911 dbSNP
rs230664 1915 dbSNP
rs1185402942 1917 dbSNP
rs1197640622 1919 dbSNP
rs761677713 1920 dbSNP
rs1397696643 1921 dbSNP
rs1464721703 1923 dbSNP
rs1331610922 1928 dbSNP
rs1401559340 1931 dbSNP
rs1252325735 1933 dbSNP
rs1230033503 1936 dbSNP
rs1340353371 1937 dbSNP
rs776631285 1941 dbSNP
rs190963774 1942 dbSNP
rs538839645 1944 dbSNP
rs1316300550 1956 dbSNP
rs766851552 1965 dbSNP
rs1329326842 1966 dbSNP
rs566744546 1967 dbSNP
rs1020270772 1968 dbSNP
rs1032529947 1969 dbSNP
rs980033157 1970 dbSNP
rs1456176835 1973 dbSNP
rs111770516 1975 dbSNP
rs188076042 1977 dbSNP
rs567128049 1978 dbSNP
rs1002148505 1982 dbSNP
rs1477204607 1982 dbSNP
rs1374407174 1983 dbSNP
rs748278679 1983 dbSNP
rs1046434301 1999 dbSNP
rs1301411783 2000 dbSNP
rs1402138489 2002 dbSNP
rs746802293 2003 dbSNP
rs1315348177 2005 dbSNP
rs1338594468 2007 dbSNP
rs550595488 2010 dbSNP
rs530484301 2011 dbSNP
rs887585365 2017 dbSNP
rs1046687786 2022 dbSNP
rs1048865864 2023 dbSNP
rs931834626 2026 dbSNP
rs768897708 2031 dbSNP
rs1260912764 2033 dbSNP
rs1252205858 2036 dbSNP
rs1207650927 2038 dbSNP
rs1193708194 2042 dbSNP
rs1263438806 2044 dbSNP
rs929738344 2045 dbSNP
rs1174406009 2050 dbSNP
rs796595967 2055 dbSNP
rs779756663 2058 dbSNP
rs919639740 2063 dbSNP
rs745631340 2064 dbSNP
rs1223893476 2067 dbSNP
rs1399509055 2071 dbSNP
rs1362199015 2077 dbSNP
rs900408081 2085 dbSNP
rs942555578 2090 dbSNP
rs911038761 2092 dbSNP
rs987138614 2099 dbSNP
rs1040698403 2100 dbSNP
rs955287010 2104 dbSNP
rs1300836336 2105 dbSNP
rs1312611923 2110 dbSNP
rs1236187196 2117 dbSNP
rs912582858 2119 dbSNP
rs1216724498 2132 dbSNP
rs1261903217 2137 dbSNP
rs530766779 2137 dbSNP
rs778589839 2137 dbSNP
rs112749139 2139 dbSNP
rs935385118 2142 dbSNP
rs1455010411 2146 dbSNP
rs988772156 2147 dbSNP
rs1195843657 2157 dbSNP
rs564643270 2159 dbSNP
rs957353862 2164 dbSNP
rs1033128017 2165 dbSNP
rs1336627300 2166 dbSNP
rs1353896213 2184 dbSNP
rs149688507 2187 dbSNP
rs970000934 2189 dbSNP
rs182548361 2196 dbSNP
rs992377287 2200 dbSNP
rs190355855 2201 dbSNP
rs542930746 2204 dbSNP
rs574323045 2205 dbSNP
rs1157533896 2212 dbSNP
rs1046720212 2218 dbSNP
rs1315082626 2219 dbSNP
rs1224338005 2221 dbSNP
rs1309040618 2223 dbSNP
rs1319452423 2225 dbSNP
rs749180630 2225 dbSNP
rs557069789 2227 dbSNP
rs1215954750 2229 dbSNP
rs1236654785 2230 dbSNP
rs777904818 2239 dbSNP
rs1432174841 2248 dbSNP
rs1178339128 2249 dbSNP
rs139497615 2261 dbSNP
rs752282610 2264 dbSNP
rs1422170833 2265 dbSNP
rs900343467 2270 dbSNP
rs578109207 2282 dbSNP
rs942439423 2285 dbSNP
rs1490996049 2292 dbSNP
rs911057676 2294 dbSNP
rs558305114 2296 dbSNP
rs749333815 2297 dbSNP
rs1442633639 2300 dbSNP
rs538803284 2303 dbSNP
rs1262501357 2315 dbSNP
rs935354061 2323 dbSNP
rs1227264238 2325 dbSNP
rs531061967 2326 dbSNP
rs775094606 2331 dbSNP
rs1283730997 2333 dbSNP
rs957388061 2334 dbSNP
rs979925798 2336 dbSNP
rs1032994949 2340 dbSNP
rs1457633713 2341 dbSNP
rs916747715 2342 dbSNP
rs980612387 2346 dbSNP
rs185944818 2361 dbSNP
rs970140092 2364 dbSNP
rs1482531453 2366 dbSNP
rs780939237 2373 dbSNP
rs1382643158 2385 dbSNP
rs1476220773 2389 dbSNP
rs1168862099 2392 dbSNP
rs1386506975 2393 dbSNP
rs1170287636 2394 dbSNP
rs1469034152 2400 dbSNP
rs1429520279 2406 dbSNP
rs1330581216 2407 dbSNP
rs1357368824 2410 dbSNP
rs1447111231 2416 dbSNP
rs1313400033 2421 dbSNP
rs613686 2425 dbSNP
rs751883419 2430 dbSNP
rs1397558124 2431 dbSNP
rs1481637356 2433 dbSNP
rs908161517 2456 dbSNP
rs536151254 2469 dbSNP
rs1014387876 2471 dbSNP
rs1339605579 2483 dbSNP
rs1354057213 2486 dbSNP
rs1275475515 2490 dbSNP
rs567563033 2495 dbSNP
rs181656285 2496 dbSNP
rs1258803660 2504 dbSNP
rs1486717226 2505 dbSNP
rs951839681 2506 dbSNP
rs1027374222 2513 dbSNP
rs530552719 2517 dbSNP
rs777943926 2518 dbSNP
rs766646817 2523 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uugauauguuGGA-GGAUGGAGu 5'
                    ||| |||||||| 
Target 5' ---------cCCUACCUACCUCa 3'
 		1 - 14
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000340067.3 | 3UTR | CCCUACCUACCUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.35 0.01 -0.378 0 49 Click to see details
THCA 0.302 0.01 0.266 0.02 59 Click to see details
PAAD 0.931 0.03 1.000 0.5 4 Click to see details
STAD 0.251 0.08 0.393 0.01 32 Click to see details
LUAD 0.26 0.21 0.196 0.27 12 Click to see details
HNSC -0.127 0.21 -0.151 0.17 42 Click to see details
LUSC -0.128 0.22 -0.229 0.08 38 Click to see details
BRCA 0.071 0.26 -0.038 0.37 84 Click to see details
KIRC 0.078 0.26 0.054 0.33 68 Click to see details
KICH 0.106 0.31 -0.001 0.5 25 Click to see details
UCEC 0.12 0.31 -0.142 0.28 19 Click to see details
PCPG 0.543 0.32 0.500 0.33 3 Click to see details
PRAD 0.068 0.32 -0.017 0.45 50 Click to see details
CHOL 0.176 0.33 0.167 0.33 9 Click to see details
CESC 0.498 0.33 0.500 0.33 3 Click to see details
KIRP 0.071 0.35 -0.003 0.49 32 Click to see details
ESCA -0.129 0.35 -0.145 0.34 11 Click to see details
COAD 0.148 0.36 0.119 0.39 8 Click to see details
BLCA 0.016 0.47 0.009 0.49 18 Click to see details
BLCA 0.016 0.47 0.009 0.49 18 Click to see details
BLCA 0.016 0.47 0.009 0.49 18 Click to see details
581 hsa-let-7e-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT002081 HMGA2 high mobility group AT-hook 2 5 5
MIRT003932 EIF3J eukaryotic translation initiation factor 3 subunit J 2 1
MIRT004469 SMC1A structural maintenance of chromosomes 1A 4 7
MIRT005718 WNT1 Wnt family member 1 4 1
MIRT006122 CCND1 cyclin D1 5 4
MIRT006404 MPL MPL proto-oncogene, thrombopoietin receptor 1 1
MIRT032098 RABGAP1L RAB GTPase activating protein 1 like 1 1
MIRT032099 DAD1 defender against cell death 1 1 1
MIRT032100 MYCN MYCN proto-oncogene, bHLH transcription factor 4 2
MIRT051413 WDR67 TBC1 domain family member 31 1 1
MIRT051414 FAM219B family with sequence similarity 219 member B 1 1
MIRT051415 C11orf91 chromosome 11 open reading frame 91 1 1
MIRT051416 CENPP centromere protein P 1 1
MIRT051417 TMEM107 transmembrane protein 107 1 1
MIRT051418 SREBF1 sterol regulatory element binding transcription factor 1 1 1
MIRT051419 DAAM1 dishevelled associated activator of morphogenesis 1 1 1
MIRT051420 DGCR8 DGCR8, microprocessor complex subunit 1 1
MIRT051421 RAP1A RAP1A, member of RAS oncogene family 1 1
MIRT051422 RPA1 replication protein A1 1 1
MIRT051423 SKIV2L Ski2 like RNA helicase 1 1
MIRT051424 AGO1 argonaute 1, RISC catalytic component 4 2
MIRT051425 RPS27 ribosomal protein S27 1 1
MIRT051426 ARNT2 aryl hydrocarbon receptor nuclear translocator 2 1 1
MIRT051427 GPM6B glycoprotein M6B 1 1
MIRT051428 TTLL12 tubulin tyrosine ligase like 12 1 1
MIRT051429 HIST2H2BF histone cluster 2 H2B family member f 1 1
MIRT051430 CELF2 CUGBP Elav-like family member 2 1 1
MIRT051431 AGO2 argonaute 2, RISC catalytic component 1 1
MIRT051432 VPS13D vacuolar protein sorting 13 homolog D 1 1
MIRT051433 RPL10 ribosomal protein L10 1 1
MIRT051434 SPCS2 signal peptidase complex subunit 2 1 1
MIRT051435 DCAF8 DDB1 and CUL4 associated factor 8 1 1
MIRT051436 CTC1 CST telomere replication complex component 1 1 1
MIRT051437 NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1 1
MIRT051438 PHF3 PHD finger protein 3 1 1
MIRT051439 TUBA1B tubulin alpha 1b 1 1
MIRT051440 SHANK1 SH3 and multiple ankyrin repeat domains 1 1 1
MIRT051441 SKA2 spindle and kinetochore associated complex subunit 2 1 1
MIRT051442 SPTBN1 spectrin beta, non-erythrocytic 1 1 1
MIRT051443 ND2 MTND2 1 1
MIRT051444 MED13L mediator complex subunit 13 like 1 1
MIRT051445 RCOR3 REST corepressor 3 1 1
MIRT051446 MACF1 microtubule-actin crosslinking factor 1 1 1
MIRT051447 RDX radixin 2 5
MIRT051448 PCBP2 poly(rC) binding protein 2 1 1
MIRT051449 UBAP2L ubiquitin associated protein 2 like 1 1
MIRT051450 CDCA3 cell division cycle associated 3 1 1
MIRT051451 CABLES1 Cdk5 and Abl enzyme substrate 1 1 1
MIRT051452 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1 1
MIRT051453 C12orf49 chromosome 12 open reading frame 49 1 1
MIRT051454 TIMP3 TIMP metallopeptidase inhibitor 3 1 1
MIRT051455 WBSCR16 RCC1 like 1 1
MIRT051456 SLC2A11 solute carrier family 2 member 11 1 1
MIRT051457 NF1 neurofibromin 1 1 1
MIRT051458 LRRC8A leucine rich repeat containing 8 VRAC subunit A 1 1
MIRT051459 RUNX1T1 RUNX1 translocation partner 1 1 1
MIRT051460 DTNB dystrobrevin beta 1 1
MIRT051461 SCMH1 Scm polycomb group protein homolog 1 1 1
MIRT051462 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma 1 1
MIRT051463 RHBDD2 rhomboid domain containing 2 1 1
MIRT051464 ND5 NADH dehydrogenase, subunit 5 (complex I) 1 1
MIRT051465 NDST1 N-deacetylase and N-sulfotransferase 1 1 1
MIRT051466 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 5
MIRT051467 EIF4A1 eukaryotic translation initiation factor 4A1 1 1
MIRT051468 BAHCC1 BAH domain and coiled-coil containing 1 1 1
MIRT051469 CARM1 coactivator associated arginine methyltransferase 1 1 1
MIRT051470 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 1 1
MIRT051471 ND3 NADH dehydrogenase, subunit 3 (complex I) 1 1
MIRT051472 PIGS phosphatidylinositol glycan anchor biosynthesis class S 1 1
MIRT051473 ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1 1
MIRT051474 RPN2 ribophorin II 1 1
MIRT051475 RPL12 ribosomal protein L12 1 1
MIRT051476 NME4 NME/NM23 nucleoside diphosphate kinase 4 1 1
MIRT051477 IVD isovaleryl-CoA dehydrogenase 1 1
MIRT051478 JAZF1 JAZF zinc finger 1 1 1
MIRT051479 ND4 NADH dehydrogenase, subunit 4 (complex I) 1 1
MIRT051480 VARS valyl-tRNA synthetase 1 1
MIRT051481 RNF26 ring finger protein 26 1 1
MIRT051482 LHFPL2 LHFPL tetraspan subfamily member 2 1 1
MIRT051483 ARCN1 archain 1 1 1
MIRT051484 COX1 cytochrome c oxidase subunit I 1 1
MIRT051485 SLC12A4 solute carrier family 12 member 4 1 1
MIRT051486 AEBP2 AE binding protein 2 1 1
MIRT051487 PET112 glutamyl-tRNA amidotransferase subunit B 1 1
MIRT051488 UROC1 urocanate hydratase 1 1 1
MIRT051489 IGF1R insulin like growth factor 1 receptor 5 10
MIRT051490 BSDC1 BSD domain containing 1 1 1
MIRT051491 PTK2 protein tyrosine kinase 2 1 1
MIRT051492 CDC5L cell division cycle 5 like 1 1
MIRT051493 EN2 engrailed homeobox 2 1 1
MIRT051494 SSB Sjogren syndrome antigen B 1 1
MIRT051495 SLCO3A1 solute carrier organic anion transporter family member 3A1 1 1
MIRT051496 RRAGC Ras related GTP binding C 1 1
MIRT051497 ZNF236 zinc finger protein 236 1 1
MIRT051498 SEMA4B semaphorin 4B 1 1
MIRT051499 SERBP1 SERPINE1 mRNA binding protein 1 1 1
MIRT051500 XIAP X-linked inhibitor of apoptosis 1 1
MIRT051501 GTF2I general transcription factor IIi 1 1
MIRT051502 JMJD1C jumonji domain containing 1C 1 1
MIRT051503 OTUD5 OTU deubiquitinase 5 1 1
MIRT051504 NOLC1 nucleolar and coiled-body phosphoprotein 1 1 1
MIRT051505 PPIG peptidylprolyl isomerase G 1 1
MIRT051506 PSMD2 proteasome 26S subunit, non-ATPase 2 1 1
MIRT051507 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1 1
MIRT051508 VAMP2 vesicle associated membrane protein 2 1 1
MIRT051509 LSR lipolysis stimulated lipoprotein receptor 1 1
MIRT051510 KIAA0355 KIAA0355 1 1
MIRT051511 RPSA ribosomal protein SA 1 1
MIRT051512 DCAF6 DDB1 and CUL4 associated factor 6 1 1
MIRT051513 UHRF1BP1 UHRF1 binding protein 1 1 1
MIRT051514 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1 1
MIRT051515 PIGP phosphatidylinositol glycan anchor biosynthesis class P 1 1
MIRT051516 LMLN leishmanolysin like peptidase 1 1
MIRT051517 PPP2R1A protein phosphatase 2 scaffold subunit Aalpha 1 1
MIRT051518 HIPK1 homeodomain interacting protein kinase 1 1 1
MIRT051519 SERF2 small EDRK-rich factor 2 1 1
MIRT051520 RBM4 RNA binding motif protein 4 1 1
MIRT051521 RBM14 RNA binding motif protein 14 1 1
MIRT051522 HMGB1 high mobility group box 1 1 1
MIRT051523 GMPS guanine monophosphate synthase 1 1
MIRT051524 DIAPH1 diaphanous related formin 1 1 1
MIRT051525 STAM signal transducing adaptor molecule 1 1
MIRT051526 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 1 1
MIRT051527 APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 1 1
MIRT051528 MARCH5 membrane associated ring-CH-type finger 5 1 1
MIRT051529 SQLE squalene epoxidase 1 1
MIRT051530 TIMM50 translocase of inner mitochondrial membrane 50 1 1
MIRT051531 NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 1 1
MIRT051532 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 1 1
MIRT051533 NRSN2 neurensin 2 1 1
MIRT051534 SALL1 spalt like transcription factor 1 1 1
MIRT051535 COX3 cytochrome c oxidase III 1 1
MIRT051536 RABL6 RAB, member RAS oncogene family like 6 1 1
MIRT051537 SUPT4H1 SPT4 homolog, DSIF elongation factor subunit 1 1
MIRT051538 PACS2 phosphofurin acidic cluster sorting protein 2 1 1
MIRT051539 MTMR14 myotubularin related protein 14 1 1
MIRT051540 LUZP1 leucine zipper protein 1 1 1
MIRT051541 PFAS phosphoribosylformylglycinamidine synthase 1 1
MIRT051542 SUZ12 SUZ12 polycomb repressive complex 2 subunit 1 1
MIRT051543 PAPD4 poly(A) RNA polymerase D4, non-canonical 1 1
MIRT051544 QSOX1 quiescin sulfhydryl oxidase 1 1 1
MIRT051545 SPATA13 spermatogenesis associated 13 1 1
MIRT051546 DHX57 DExH-box helicase 57 1 1
MIRT051547 KATNB1 katanin regulatory subunit B1 1 1
MIRT051548 COL6A1 collagen type VI alpha 1 chain 1 1
MIRT051549 DHX15 DEAH-box helicase 15 1 1
MIRT051550 MTCH2 mitochondrial carrier 2 1 1
MIRT051551 KIAA0100 KIAA0100 1 1
MIRT051552 SUGP2 SURP and G-patch domain containing 2 1 1
MIRT051553 NCLN nicalin 1 1
MIRT051554 ATXN2L ataxin 2 like 1 1
MIRT051555 CHD9 chromodomain helicase DNA binding protein 9 1 1
MIRT051556 PES1 pescadillo ribosomal biogenesis factor 1 1 1
MIRT051557 NUP155 nucleoporin 155 2 7
MIRT051558 GNG5 G protein subunit gamma 5 2 3
MIRT051559 ARHGAP19 Rho GTPase activating protein 19 1 1
MIRT051560 MTFR1 mitochondrial fission regulator 1 1 1
MIRT051561 IRS2 insulin receptor substrate 2 2 1
MIRT051562 IRS4 insulin receptor substrate 4 1 1
MIRT051563 PPP1R10 protein phosphatase 1 regulatory subunit 10 1 1
MIRT051564 ZNF284 zinc finger protein 284 1 1
MIRT051565 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 1 1
MIRT051566 SCD stearoyl-CoA desaturase 1 1
MIRT051567 FDPS farnesyl diphosphate synthase 1 1
MIRT051568 KRBOX4 KRAB box domain containing 4 1 1
MIRT051569 BRI3 brain protein I3 1 1
MIRT051570 CHD7 chromodomain helicase DNA binding protein 7 1 1
MIRT051571 PYCR1 pyrroline-5-carboxylate reductase 1 1 1
MIRT051572 SMAP2 small ArfGAP2 1 1
MIRT051573 WDFY3 WD repeat and FYVE domain containing 3 1 1
MIRT051574 CRK CRK proto-oncogene, adaptor protein 1 1
MIRT051575 SRSF2 serine and arginine rich splicing factor 2 1 1
MIRT051576 PGD phosphogluconate dehydrogenase 1 1
MIRT051577 RMND5A required for meiotic nuclear division 5 homolog A 1 1
MIRT051578 ZNF652 zinc finger protein 652 1 1
MIRT051579 PSMA6 proteasome subunit alpha 6 1 1
MIRT051580 SLC38A2 solute carrier family 38 member 2 1 1
MIRT051581 LRRC41 leucine rich repeat containing 41 1 1
MIRT051582 RANBP2 RAN binding protein 2 1 1
MIRT051583 SVIL supervillin 1 1
MIRT051584 CCNG1 cyclin G1 1 1
MIRT051585 ZNF256 zinc finger protein 256 1 1
MIRT051586 COPG1 coatomer protein complex subunit gamma 1 1 1
MIRT051587 PDCD11 programmed cell death 11 1 1
MIRT051588 CNBP CCHC-type zinc finger nucleic acid binding protein 1 1
MIRT051589 USP37 ubiquitin specific peptidase 37 1 1
MIRT051590 UBE2V2 ubiquitin conjugating enzyme E2 V2 1 1
MIRT051591 UBE2H ubiquitin conjugating enzyme E2 H 1 1
MIRT051592 LMNA lamin A/C 1 1
MIRT051593 STAT3 signal transducer and activator of transcription 3 1 1
MIRT051594 TRPV1 transient receptor potential cation channel subfamily V member 1 1 1
MIRT051595 MATR3 matrin 3 1 1
MIRT051596 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1 1
MIRT051597 HS6ST2 heparan sulfate 6-O-sulfotransferase 2 1 1
MIRT051598 WDR48 WD repeat domain 48 1 1
MIRT051599 RBM8A RNA binding motif protein 8A 1 1
MIRT051600 SCYL1 SCY1 like pseudokinase 1 1 1
MIRT051601 C19orf48 chromosome 19 open reading frame 48 1 1
MIRT051602 FOXD4L6 forkhead box D4 like 6 1 1
MIRT051603 PIGN phosphatidylinositol glycan anchor biosynthesis class N 1 1
MIRT051604 SPCS3 signal peptidase complex subunit 3 1 1
MIRT051605 TNFAIP1 TNF alpha induced protein 1 1 1
MIRT051606 MS4A10 membrane spanning 4-domains A10 1 1
MIRT051607 MSMO1 methylsterol monooxygenase 1 1 1
MIRT051608 ARID1A AT-rich interaction domain 1A 1 1
MIRT051609 NCKIPSD NCK interacting protein with SH3 domain 2 5
MIRT051610 NCBP1 nuclear cap binding protein subunit 1 1 1
MIRT051611 COX16 COX16, cytochrome c oxidase assembly homolog 1 1
MIRT051612 NUDT8 nudix hydrolase 8 1 1
MIRT051613 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT051614 TXNRD1 thioredoxin reductase 1 1 1
MIRT051615 ELMSAN1 ELM2 and Myb/SANT domain containing 1 1 1
MIRT051616 CTSA cathepsin A 1 1
MIRT051617 PRRC2A proline rich coiled-coil 2A 1 1
MIRT051618 SPAG9 sperm associated antigen 9 1 1
MIRT051619 AGMAT agmatinase 1 1
MIRT051620 NCKAP5L NCK associated protein 5 like 1 1
MIRT051621 ZFP62 ZFP62 zinc finger protein 1 1
MIRT051622 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1 1
MIRT051623 POLR3D RNA polymerase III subunit D 2 3
MIRT051624 PRPF8 pre-mRNA processing factor 8 1 1
MIRT051625 ATP6 ATP synthase F0 subunit 6 1 1
MIRT051626 ZFAND5 zinc finger AN1-type containing 5 1 1
MIRT051627 BAZ1B bromodomain adjacent to zinc finger domain 1B 1 1
MIRT051628 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT051629 BMP2K BMP2 inducible kinase 1 1
MIRT051630 SPN sialophorin 1 1
MIRT051631 PA2G4 proliferation-associated 2G4 1 1
MIRT051632 RPRD2 regulation of nuclear pre-mRNA domain containing 2 1 1
MIRT051633 TUBB4B tubulin beta 4B class IVb 1 1
MIRT051634 TRRAP transformation/transcription domain associated protein 1 1
MIRT051635 SLCO4A1 solute carrier organic anion transporter family member 4A1 1 1
MIRT051636 CCRN4L nocturnin 1 1
MIRT051637 USE1 unconventional SNARE in the ER 1 1 1
MIRT051638 STARD7 StAR related lipid transfer domain containing 7 1 1
MIRT051639 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 3
MIRT051640 CLTC clathrin heavy chain 1 1
MIRT051641 TERF1 telomeric repeat binding factor 1 1 1
MIRT051642 PAX3 paired box 3 1 1
MIRT051643 CCDC97 coiled-coil domain containing 97 1 1
MIRT051644 HLA-C major histocompatibility complex, class I, C 1 1
MIRT051645 GTPBP8 GTP binding protein 8 (putative) 1 1
MIRT051646 VGLL4 vestigial like family member 4 1 1
MIRT051647 ANKRD40 ankyrin repeat domain 40 1 1
MIRT051648 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 1 1
MIRT051649 ND1 NADH dehydrogenase, subunit 1 (complex I) 1 1
MIRT051650 DSP desmoplakin 1 1
MIRT051651 UBN2 ubinuclein 2 1 1
MIRT051652 ZNF805 zinc finger protein 805 1 1
MIRT051653 RBBP4 RB binding protein 4, chromatin remodeling factor 1 1
MIRT051654 OCLN occludin 1 1
MIRT051655 CBX5 chromobox 5 2 3
MIRT051656 AMPD2 adenosine monophosphate deaminase 2 1 1
MIRT051657 MKI67 marker of proliferation Ki-67 1 1
MIRT051658 SUB1 SUB1 homolog, transcriptional regulator 1 1
MIRT051659 RSL1D1 ribosomal L1 domain containing 1 1 1
MIRT051660 SEC23IP SEC23 interacting protein 1 1
MIRT051661 RNMT RNA guanine-7 methyltransferase 1 1
MIRT051662 SGSM3 small G protein signaling modulator 3 1 1
MIRT051663 ZFP3 ZFP3 zinc finger protein 1 1
MIRT051664 GLUL glutamate-ammonia ligase 1 1
MIRT051665 POLD1 DNA polymerase delta 1, catalytic subunit 1 1
MIRT051666 WDR4 WD repeat domain 4 1 1
MIRT051667 PPP1R2 protein phosphatase 1 regulatory inhibitor subunit 2 1 1
MIRT051668 RAI2 retinoic acid induced 2 1 1
MIRT051669 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 1 1
MIRT051670 UTP15 UTP15, small subunit processome component 1 1
MIRT051671 THADA THADA, armadillo repeat containing 1 1
MIRT051672 ZNF451 zinc finger protein 451 1 1
MIRT051673 CREBBP CREB binding protein 1 1
MIRT051674 ZNF770 zinc finger protein 770 1 1
MIRT051675 CLDN4 claudin 4 1 1
MIRT051676 ZKSCAN7 zinc finger with KRAB and SCAN domains 7 1 1
MIRT051677 NICN1 nicolin 1 1 1
MIRT051678 RPLP2 ribosomal protein lateral stalk subunit P2 1 1
MIRT051679 DCBLD2 discoidin, CUB and LCCL domain containing 2 1 1
MIRT051680 IRGQ immunity related GTPase Q 1 1
MIRT051681 CA5B carbonic anhydrase 5B 1 1
MIRT051682 COX14 COX14, cytochrome c oxidase assembly factor 1 1
MIRT051683 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT051684 RPL27A ribosomal protein L27a 1 1
MIRT051685 CWC15 CWC15 spliceosome associated protein homolog 1 1
MIRT051686 NT5DC2 5'-nucleotidase domain containing 2 1 1
MIRT051687 OR7D2 olfactory receptor family 7 subfamily D member 2 1 1
MIRT051688 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 1 1
MIRT051689 NUDT15 nudix hydrolase 15 1 1
MIRT051690 CDH18 cadherin 18 1 1
MIRT051691 FAM160B1 family with sequence similarity 160 member B1 1 1
MIRT051692 DZIP1 DAZ interacting zinc finger protein 1 1 1
MIRT051693 TDRD7 tudor domain containing 7 1 1
MIRT051694 TCF4 transcription factor 4 1 1
MIRT051695 ENSA endosulfine alpha 1 1
MIRT051696 GTF3C1 general transcription factor IIIC subunit 1 1 1
MIRT051697 TNFRSF1A TNF receptor superfamily member 1A 1 1
MIRT051698 CCDC113 coiled-coil domain containing 113 1 1
MIRT051699 MYO9B myosin IXB 1 1
MIRT051700 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 1 1
MIRT051701 PRAMEF13 PRAME family member 13 1 1
MIRT051702 PMPCA peptidase, mitochondrial processing alpha subunit 2 5
MIRT051703 MRPS2 mitochondrial ribosomal protein S2 1 1
MIRT051704 RACGAP1 Rac GTPase activating protein 1 1 1
MIRT051705 CCDC106 coiled-coil domain containing 106 1 1
MIRT051706 CYP2B6 cytochrome P450 family 2 subfamily B member 6 1 1
MIRT051707 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 3
MIRT051708 PSME4 proteasome activator subunit 4 1 1
MIRT051709 SETD1A SET domain containing 1A 1 1
MIRT054561 MMP9 matrix metallopeptidase 9 3 1
MIRT054579 IGF1 insulin like growth factor 1 3 1
MIRT063195 ADIPOR2 adiponectin receptor 2 2 2
MIRT065687 ESPL1 extra spindle pole bodies like 1, separase 2 4
MIRT067399 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT068154 TXLNA taxilin alpha 2 2
MIRT068528 NHLRC3 NHL repeat containing 3 2 6
MIRT068789 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073006 ARID3B AT-rich interaction domain 3B 2 6
MIRT076223 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT077616 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT080398 ONECUT2 one cut homeobox 2 2 2
MIRT083300 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084976 BACH1 BTB domain and CNC homolog 1 2 2
MIRT094160 PCGF3 polycomb group ring finger 3 2 6
MIRT094460 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT095766 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT100094 ABT1 activator of basal transcription 1 2 8
MIRT112242 MDM4 MDM4, p53 regulator 2 4
MIRT118586 STK4 serine/threonine kinase 4 2 2
MIRT120921 PDE12 phosphodiesterase 12 2 8
MIRT123317 CALU calumenin 2 2
MIRT152272 TNFSF9 TNF superfamily member 9 2 2
MIRT153847 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168583 HMGA1 high mobility group AT-hook 1 2 4
MIRT180603 CRY2 cryptochrome circadian clock 2 2 2
MIRT187717 SUOX sulfite oxidase 2 2
MIRT191404 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193101 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215720 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218815 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240330 UBXN2B UBX domain protein 2B 2 2
MIRT243473 TRIM71 tripartite motif containing 71 2 2
MIRT244069 EDN1 endothelin 1 2 2
MIRT252330 SALL3 spalt like transcription factor 3 2 2
MIRT255314 CDV3 CDV3 homolog 2 2
MIRT259277 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259479 TXLNG taxilin gamma 2 2
MIRT260707 CLDN12 claudin 12 2 6
MIRT264693 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT266212 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266626 CHTOP chromatin target of PRMT1 2 2
MIRT268839 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT294446 ZNF264 zinc finger protein 264 2 2
MIRT297013 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT297443 SLC20A1 solute carrier family 20 member 1 2 4
MIRT300037 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300893 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303320 MXD1 MAX dimerization protein 1 2 2
MIRT309846 NAT8L N-acetyltransferase 8 like 2 2
MIRT322428 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324731 ACER2 alkaline ceramidase 2 2 2
MIRT402057 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437395 LIN28A lin-28 homolog A 4 1
MIRT437396 AURKB aurora kinase B 4 1
MIRT437435 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2 1
MIRT438632 TNFRSF10B TNF receptor superfamily member 10b 2 1
MIRT439135 MYC MYC proto-oncogene, bHLH transcription factor 0 1
MIRT442020 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445658 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447136 KIF27 kinesin family member 27 2 2
MIRT448259 ZNF774 zinc finger protein 774 2 2
MIRT449005 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449953 FMNL3 formin like 3 2 2
MIRT451155 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451624 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451693 C1RL complement C1r subcomponent like 2 2
MIRT452092 NUCB2 nucleobindin 2 2 2
MIRT452431 QDPR quinoid dihydropteridine reductase 2 2
MIRT452943 DISC1 disrupted in schizophrenia 1 2 2
MIRT453401 RHD Rh blood group D antigen 2 6
MIRT454164 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454280 FXN frataxin 2 2
MIRT454539 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454854 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455676 GLO1 glyoxalase I 2 2
MIRT457248 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457677 ZNF587 zinc finger protein 587 2 2
MIRT457887 THEM6 thioesterase superfamily member 6 2 4
MIRT458016 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458279 FUT10 fucosyltransferase 10 2 2
MIRT459736 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460453 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460500 FAM105A family with sequence similarity 105 member A 2 6
MIRT460938 NOA1 nitric oxide associated 1 2 4
MIRT461092 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461169 SLC11A2 solute carrier family 11 member 2 2 4
MIRT461364 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462382 YAE1D1 Yae1 domain containing 1 2 2
MIRT462780 ZNF8 zinc finger protein 8 2 2
MIRT463420 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463662 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464265 VCL vinculin 2 2
MIRT465122 TSC22D2 TSC22 domain family member 2 2 4
MIRT466184 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466722 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469102 RNF144B ring finger protein 144B 2 2
MIRT469714 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470425 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470679 POLR2D RNA polymerase II subunit D 2 4
MIRT470861 PLXND1 plexin D1 2 2
MIRT471271 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471957 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472672 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 2
MIRT472739 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473134 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473234 SMCR7L mitochondrial elongation factor 1 1 4
MIRT473828 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473940 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474022 LRRC20 leucine rich repeat containing 20 2 2
MIRT474502 KLHDC8B kelch domain containing 8B 2 2
MIRT474766 KIAA0930 KIAA0930 2 2
MIRT474905 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475331 IFNLR1 interferon lambda receptor 1 2 2
MIRT475379 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475733 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476548 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476973 FAM83G family with sequence similarity 83 member G 2 4
MIRT477534 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 2 4
MIRT477682 EFHD2 EF-hand domain family member D2 2 2
MIRT481201 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481241 ATXN7L3 ataxin 7 like 3 2 2
MIRT481363 ATG9A autophagy related 9A 2 2
MIRT481388 ATG12 autophagy related 12 2 2
MIRT481652 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481851 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482184 AHR aryl hydrocarbon receptor 2 2
MIRT482220 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485296 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486659 ZNF28 zinc finger protein 28 2 2
MIRT489413 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491867 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492216 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492626 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493323 LIMD2 LIM domain containing 2 2 2
MIRT493901 FAM43A family with sequence similarity 43 member A 2 4
MIRT494263 CEP120 centrosomal protein 120 2 2
MIRT494687 ARID3A AT-rich interaction domain 3A 2 2
MIRT495968 TBC1D19 TBC1 domain family member 19 2 2
MIRT496111 SNX17 sorting nexin 17 2 2
MIRT497875 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498122 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499405 PLCG2 phospholipase C gamma 2 2 4
MIRT499493 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499653 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499942 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499997 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500819 THBS1 thrombospondin 1 2 3
MIRT500902 STRN striatin 2 4
MIRT501118 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501173 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501202 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501241 SEMA4C semaphorin 4C 2 6
MIRT501328 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501355 RNF44 ring finger protein 44 2 4
MIRT501387 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501441 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501759 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501943 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502106 KPNA5 karyopherin subunit alpha 5 2 8
MIRT502130 KMT2D lysine methyltransferase 2D 2 4
MIRT502784 CEP135 centrosomal protein 135 2 2
MIRT502845 CELF1 CUGBP Elav-like family member 1 2 2
MIRT504789 C12orf4 chromosome 12 open reading frame 4 2 2
MIRT505017 ZNF644 zinc finger protein 644 2 2
MIRT506942 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507252 FIGN fidgetin, microtubule severing factor 2 8
MIRT507694 COIL coilin 2 6
MIRT508401 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508665 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508932 AK4 adenylate kinase 4 2 4
MIRT510395 ZNF566 zinc finger protein 566 2 6
MIRT510518 YOD1 YOD1 deubiquitinase 2 6
MIRT511386 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512745 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515954 C9orf156 tRNA methyltransferase O 2 2
MIRT516083 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT523619 FZD9 frizzled class receptor 9 2 4
MIRT523733 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523990 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524113 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525727 SOD2 superoxide dismutase 2 2 2
MIRT527763 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529727 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533187 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536378 LEFTY1 left-right determination factor 1 2 2
MIRT543785 RBM12B RNA binding motif protein 12B 2 4
MIRT543868 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545387 PM20D2 peptidase M20 domain containing 2 2 2
MIRT545890 ZNF200 zinc finger protein 200 2 4
MIRT546334 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547373 MSI2 musashi RNA binding protein 2 2 2
MIRT547579 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548264 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548351 EPHA4 EPH receptor A4 2 2
MIRT548534 DUSP1 dual specificity phosphatase 1 2 2
MIRT548560 DNAL1 dynein axonemal light chain 1 2 2
MIRT548779 COLEC12 collectin subfamily member 12 2 2
MIRT548978 CCNT2 cyclin T2 2 2
MIRT549208 BEND4 BEN domain containing 4 2 4
MIRT549763 ZNF611 zinc finger protein 611 2 6
MIRT549799 KIAA0391 KIAA0391 2 2
MIRT549847 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550898 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551283 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551318 GSG2 histone H3 associated protein kinase 2 6
MIRT551932 AKAP8 A-kinase anchoring protein 8 2 4
MIRT552003 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552410 ZNF460 zinc finger protein 460 2 4
MIRT553013 USP38 ubiquitin specific peptidase 38 2 2
MIRT555550 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555711 PDZD8 PDZ domain containing 8 2 2
MIRT557372 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT557960 FAM222B family with sequence similarity 222 member B 2 2
MIRT559087 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559497 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561772 PEG10 paternally expressed 10 2 2
MIRT564402 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565443 SURF4 surfeit 4 2 2
MIRT566518 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567715 E2F6 E2F transcription factor 6 2 2
MIRT568655 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569498 THYN1 thymocyte nuclear protein 1 2 2
MIRT573820 TGOLN2 trans-golgi network protein 2 2 2
MIRT574363 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574750 GOLGA4 golgin A4 2 2
MIRT574788 FAM104A family with sequence similarity 104 member A 2 2
MIRT576089 Poteg POTE ankyrin domain family, member G 2 2
MIRT576812 Thbs1 thrombospondin 1 2 3
MIRT616370 RWDD1 RWD domain containing 1 2 2
MIRT617851 FMO4 flavin containing monooxygenase 4 2 2
MIRT642394 ZNF556 zinc finger protein 556 2 2
MIRT680519 PRIM2 DNA primase subunit 2 2 2
MIRT680547 ZNF584 zinc finger protein 584 2 2
MIRT680800 ZNF578 zinc finger protein 578 2 2
MIRT680838 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681141 INTS7 integrator complex subunit 7 2 2
MIRT681271 RFC2 replication factor C subunit 2 2 2
MIRT681323 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681359 BRI3BP BRI3 binding protein 2 2
MIRT681506 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681536 ZNF738 zinc finger protein 738 2 2
MIRT681658 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681738 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681797 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681869 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681941 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682102 ITGA3 integrin subunit alpha 3 2 4
MIRT682181 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682238 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682384 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682444 MTX3 metaxin 3 2 2
MIRT682604 CPA4 carboxypeptidase A4 2 2
MIRT682640 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689327 FPR1 formyl peptide receptor 1 2 2
MIRT689730 ATXN2 ataxin 2 2 2
MIRT691036 ZNF799 zinc finger protein 799 2 2
MIRT691935 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694884 ZNF417 zinc finger protein 417 2 2
MIRT695255 ZNF443 zinc finger protein 443 2 2
MIRT695413 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700589 PRSS22 protease, serine 22 2 2
MIRT701428 NHLRC2 NHL repeat containing 2 2 2
MIRT702484 KIAA1328 KIAA1328 2 2
MIRT702715 IPO9 importin 9 2 2
MIRT704028 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704418 CTPS1 CTP synthase 1 2 2
MIRT705750 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712373 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713520 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT731263 FASLG Fas ligand 3 1
MIRT732697 Ccr7 chemokine (C-C motif) receptor 7 2 0
MIRT732700 Snhg12 small nucleolar RNA host gene 12 2 0
MIRT734626 SYT7 synaptotagmin 7 1 0
MIRT755829 UBQLN4 ubiquilin 4 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7e Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
let-7e Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
let-7e Doxorubicin approved 31703 Microarray ovarian cancer 19237188 2009 up-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7e Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 up-regulated
let-7e Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7e 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
let-7e Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse liver 19270793 2009 down-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
let-7e Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 down-regulated
let-7e Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 down-regulated
let-7e 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) NULL 16078949 Microarray hepatocytes 23107762 2013 up-regulated
let-7e Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Doxorubicin 31703 NSC123127 approved resistant High Ovarian Cancer cell line (OV19, TOV21G, TOV112D, FUOV1, C13, OV2008, A2780CP, A2780S, IGROV1, T8, OVCAR5, IMCC3, A2008, OVCAR3, SKOV3, IOSER)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant High Colon Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer tissue and cell line (A2780)
hsa-let-7e Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H1155, H358, H1993)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-let-7e Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor tissue
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Esophageal Adenocarcinoma cell line (OE19)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Breast Cancer tissue and cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Plx-4720 24180719 NSC757438 resistant High Thyroid Cancer cell line (8505c, BCPAP)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive High Colorectal Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, HO8910, ES2, CAOV3, SKOV3)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-8)
hsa-let-7e Daunorubicin 30323 NSC82151 approved resistant High Acute Promyelocytic Leukemia cell line (HL60)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7C)
hsa-let-7e Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Non-Small Cell Lung Cancer cell line (PC-9)
hsa-let-7e Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Regorafenib 11167602 NSC763932 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Ribavirin+Pegylated IFNa-2b resistant tissue (chronic hepatitis C)
hsa-let-7e Exemestane 60198 NSC713563 approved sensitive cell line (MCF-7)
hsa-let-7e 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-let-7e Ethanol+Tamoxifen resistant cell line (LY2)
hsa-let-7e Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-let-7e Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-let-7e Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-let-7e Gemcitabine 60750 NSC613327 approved resistant cell line (HuH28)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (KYSE)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (OE19)
hsa-let-7e Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-let-7e Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-let-7e-5p Alvocidib 5287969 NSC649890 resistant
hsa-let-7e-5p Ethyl, methoxy, prodigisine 135829283 NSC742418 resistant
hsa-let-7e-5p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-let-7e-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e-5p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-let-7e-5p Platinum 23939 resistant High High-Grade Serous Ovarian Cancer tissue
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-let-7e-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-let-7e-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-let-7e-5p Sunitinib 5329102 NSC750690 approved sensitive tissue (clear cell renal cell carcinoma)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-let-7e-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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