miRTarBase - #MIRT477506


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pre-miRNA Information
pre-miRNA hsa-mir-758   
Genomic Coordinates chr14: 101026020 - 101026107
Synonyms MIRN758, hsa-mir-758, MIR758
Description Homo sapiens miR-758 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-758-5p
Sequence 15| GAUGGUUGACCAGAGAGCACAC |36
Evidence Experimental
Experiments SOLiD
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 16 14 + 101026049 29233923 MiREDiBase
A-to-I 21 14 + 101026054 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs372417522 1 dbSNP
rs748092616 2 dbSNP
rs1270901332 4 dbSNP
rs1364206491 5 dbSNP
rs1483583954 8 dbSNP
rs770931807 10 dbSNP
rs776760808 11 dbSNP
rs1360350664 12 dbSNP
rs759742151 13 dbSNP
rs1002938972 15 dbSNP
rs770107042 17 dbSNP
rs369242818 20 dbSNP
rs1217090272 21 dbSNP
rs763341052 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ELL2   
Synonyms MRCCAT1
Description elongation factor for RNA polymerase II 2
Transcript NM_012081   
Expression
Putative miRNA Targets on ELL2
3'UTR of ELL2
(miRNA target sites are highlighted)		 
>ELL2|NM_012081|3'UTR
   1 AACTCTGCTTGGACCAGAAGATGTGAATAAACTTAAGCTTATTTATTTAAAATTCCAAATGAGTTGCTCTAGATTCTAAA
  81 AAGGTGAAACTTTGGCTGTTGAAAGTTTCAGTATTAGTAAACTTGAGTTACTTTTTCTTTTCCATTTTACTTTGCTTCCC
 161 TGCATTTCGAAGCTGCTCTTTCTGGTCCTCCCCACCACCCCACCCCCAAGACTTGTGTTTGTTAATAGAAATAATTTTTT
 241 TAGGTATTGGGGATCCATTGTCTATATTTCAAATCAGTTTTTTTTCCTCAAAAACTTGTGTTTGTTATTAGAAATGATTT
 321 TTTAGATATTGGGGATCCAGTGTCCACACTTAAAAGTTGTATGTGTTTAAAAAACAACAACAGTAATGTGCAAGGTGAAA
 401 TGCTTTTGGATAAACGTAAGCCTATTTTCTGACGTTTCTTAATGCAAACTCTTTGCCTTAAATGGTAGAATATTTAGAAA
 481 TTTGCACAAAATTAAAAAAATAAACATTGTCTTGGAGGGTTAAAAAATAGAAAGGTGTATGTGTATAGATTCACATACAC
 561 ATATGTATATACAGGCTGACTTGATCTAGAACATTAAATCCGCCCTGCAAGTTAACCCCCCATTGCAATGGTTGCCTTAA
 641 GGTGTTTGCTAGTTGTGTACATAGTGTGGTTAATCATTAGCTACACTGCTTCCCACTTGATTAGAGCAATGGGAAGCATA
 721 CTGTGGCCTACCAGCATCTGGAAGTGTGTGCTCGATCTGTATGTGTGCAGAGGTGGTGTGGATGTGAGCGTGCATGAAGG
 801 AAAAAAAGCTGCTACTCCTAGTAGGCCAAACGCTCAGGTTAAACAACTGACGAGTGTTACTGTAGGGTGTTTTTTTGTTT
 881 TTTTGTTTTTTTTCTTCTATCAAATTGCTACTTTTGTTGTGGAAGACAAAAGCATTTCCATTTCAACGAGTTTGTCAGCT
 961 TTATTAATGTTGGGCAAAAATTGATATGTCATGAAAATGAAACAGATCTATAGTTTTGGGACAAAATTATAAAATGAAAT
1041 GTGTAGGTAACCTATTTATATACTGCTATAAAGTATTTTTTGAAGAGAGATATGCAAAGAAGCTATTACCTACATAAGAG
1121 GTATATTTAAAGATTTTTTTTTTCATCCTGGTGCCAGGAATATAAAAAAGAGTGGATATATTTAACCATAACATACTGTG
1201 ATTCATCAAACAGCACAAACTTTCATTTCATGGAGTTTATCTGTTGACATTGATTTAAACTGTCACTTGTTTTATCATGT
1281 GGGAACATAAGTTATGTGGTCAAAAATATAAGGATTTTGAATTAATGTTGATTCAAGTTGTATTGTCTTATTGTATTGTC
1361 TTTTCAAAGTGCTGCCAGTTGAAAAGGGAAGCATTATGTTTACAAATCTGTTTTGAAATGTTTGCCAAAATTTTGGTAGT
1441 GTCTTTAATAAAGATGTTTGTCTCCAGCATCCAGAAAAATAAATGAATAACTTTGTTGTGTATCACTGTAAACCAGAAAA
1521 ATGTTGGTTATCTAGAAAACTTGAGAGAGCATGTAGATTAACTTTTCTCTTTGGAGTTCTAAAACATTAACTGGAAAGAT
1601 TAGATAATATACTAAATGTATACAGAAGTATACAGACTATACAAAGACTGAAACAAGTCCCTTTTGCACTACAACTCTAT
1681 AACATTACCGCAGAAATTTTGGTTCTATGTAGCATGGACCTCCTAAGGAATTCTGTTTCTTTTAGCATTGAGATCCCTGG
1761 TGCTCTTTTTTTACCTCAGAATTGGTACAATCATTATTAAACGTTAATTTATTTCAAACTTTTTAATTGAAAAAAGGAAA
1841 GGGAAACTTAATTGGGGATAAATTCAGGCATCATATTATTATGATAGAGTCTCCTGAGTGGTTCGTCTATAGGTAATGAA
1921 CTCATTGGTGTTATTTCTTGGACATCTTGGCCTTTTAATCAAAGACTGTGTGCTGCTATTTGCTATGAGCAAGGTTTCTC
2001 AAAAGCAAAAGGTGCTTGGACCATTTGGATCACCTGAGTTAGAATCTCTAGGTATAGGGCCCAAGTATCTGCATTTTCAC
2081 AGGTTTCTTGTAGGTGACTTTCTGCAAGCTAAAGTATGAGAACCATTGGCTTGGATGTAGTTCTAAACTTTTAGGTCTGT
2161 AAATCTTGAAATCTTGAACTGAAGGTCAACTATTGGCTTTTTTTTTTTTTTAATGTCCATCATGTCAGCAGGTGCAAATC
2241 ACTTTTCCCCTTTGCATGATCTGAGGCACCTCCTCAGTTGTTTCACTGCCAACTCTTGTTTCAGAACCTGTTTACAAACA
2321 AGCCTTCCAGTTGGTGAATGGTTAGCCATTGGAGCTCCTACCCTGTACATCAGCACATCTTCTGGTTTACAAGTTGGGTA
2401 ACAATGAAAGCTGGAGATGCTAAATGGAAATCCAGCATTGCATACCCTTAGACCTGATCACATACCAGTAAAAGCCTTAA
2481 TTTAGATGTTAGTTGTATGTGTTGGACAGATCCTTGCAAAAGTGTGTCTGTCTATTAGTTGTAAATTTGAAAATTATAAA
2561 TCTCTGAATCTGCTACTATCCAAGTTTCATCCCTTTTGAAGATGAGGCATGAGCCTATTAAAATATTTATAATCATTTTT
2641 CGTCCCCTACTGCAAGACTTTTAGATTCTTACAAATGATTACTACAGGAATAGTGGCCACTTAATGTCAGTTACTCCGGT
2721 GGAAGAATTTATCTAGTTTTTTTTCTTTTCTTTTTTGGAAGGATGGTGTGAAAAATAGCAAGATTAGAGAATGAGTTGTA
2801 TAGTTTTTTCTATCACATTTCATCTAAAATGATTTGAAGGACTTTTGAAGATTTTTACCAACATCCTTAAATCAACTCCA
2881 GGTTGGATGAACAACTGATTTAAAACAAACTAAGAGAACATTAACTAGATGTGGGCTTTTTAAAATATATAGGTATTGCA
2961 TTTCCTACCTTGTTATTTATTCCACTTTGAATACTTTAGAGGGCTTAACTTTCAACTCTTTAAGGTAGTAATGGATAGTT
3041 TTATACTTGTTCTCACAAAATTGTTATGGTCAGTTTATATCATTGCTCCATGCATTGATTATAAAAATTCAGTATTAATT
3121 TTTTCTGATCTTATAAGCTTTATAGGAGTTTTCTTTTCTCTTATAAAGTGTTTCACCTTATGTAAAACAAATGCCTGCTT
3201 GCATATTGGAAGATGTTGAAATTAGTTTTAGACAAAAGTGGTCCATCAATTCAGACACTCTGCTTGGATGCCTTACCCTT
3281 TTCATTAGTGCATTCTTTGCTTCTGAAACTTGGCAGAAACTCGTTAGCCAGTCCACTGCCTTTCTGACAATGTGTGGAGT
3361 CACGTATGCTTGGTATATGCCTTTACTACTTTTAAAGTTCTACAGTTTATTACTTGCCCAAGTGTTACTAAATCCTTTTC
3441 TTATGTGTACTGGATGGAGAAAAAATTATAGCCAGCACTTTGAGAGGAAAGTTTTCAGAAACAATATTAACTGGCACTAC
3521 TAACTGAAGGCCACAGGAGATGCTATCAATGTTATTTGTAATCTGAAGATTGAACAAGGCTGTGAGGCTCATTTCAAACT
3601 ATTTTGAGGTGTTAAAATATATATATGCTGTTTCTCAGCTGTTCCACTCAAACCGTGTTAGGACTCTCAAAGGTAAAATG
3681 TCACAGGGGCTTTTCAGTTGTTACAGAGCTCAGCAGCTGTGGTTGCCCCTGTTCTACACCAATTTCAGTTCAATAAAAAT
3761 GTTAACTTTGCAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cacacgagagaCCAGUUGGUAg 5'
                     |||||||:|| 
Target 5' cttgaactgaaGGTCAACTATt 3'
 2173 - 2194 139.00 -13.50
2 
miRNA  3' cacacgagaGACCA-GUUGGUAg 5'
                   :|||| |||:||| 
Target 5' acctcagaaTTGGTACAATCATt 3'
 1773 - 1795 137.00 -13.50
3 
miRNA  3' caCACGAG----AGACCAGUUGGUAg 5'
            |||: |    | ||||:||:||| 
Target 5' ttGTGTACATAGTGTGGTTAATCATt 3'
 653 - 678 134.00 -15.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30506907 38 COSMIC
COSN30488530 55 COSMIC
COSN30500890 111 COSMIC
COSN30150724 125 COSMIC
COSN30537277 127 COSMIC
COSN16093092 281 COSMIC
COSN2127026 353 COSMIC
COSN19454404 399 COSMIC
COSN8493294 502 COSMIC
COSN26228915 535 COSMIC
COSN30538617 815 COSMIC
COSN17038034 851 COSMIC
COSN22893338 869 COSMIC
COSN31513182 977 COSMIC
COSN2127025 1010 COSMIC
COSN21333053 1073 COSMIC
COSN31487569 1082 COSMIC
COSN31534220 1120 COSMIC
COSN31534312 1126 COSMIC
COSN20101539 1133 COSMIC
COSN28708467 1198 COSMIC
COSN20780025 1231 COSMIC
COSN30545152 1282 COSMIC
COSN31487390 1365 COSMIC
COSN31606712 1375 COSMIC
COSN16036551 1458 COSMIC
COSN14981300 1500 COSMIC
COSN21471966 1504 COSMIC
COSN7587852 1543 COSMIC
COSN31530335 1567 COSMIC
COSN2127024 1790 COSMIC
COSN25043650 1861 COSMIC
COSN6715554 1862 COSMIC
COSN17181652 1913 COSMIC
COSN26268248 1934 COSMIC
COSN27267928 2198 COSMIC
COSN7779627 2234 COSMIC
COSN20101538 2744 COSMIC
COSN2127023 2775 COSMIC
COSN18805543 2814 COSMIC
COSN22999870 3125 COSMIC
COSN20760868 3146 COSMIC
COSN216843 3354 COSMIC
COSN5614582 3544 COSMIC
rs11135441 2298 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1201644275 4 dbSNP
rs1454818536 7 dbSNP
rs756951552 8 dbSNP
rs1174652230 11 dbSNP
rs200228969 14 dbSNP
rs749734407 18 dbSNP
rs1201909132 28 dbSNP
rs763840848 29 dbSNP
rs1208060058 32 dbSNP
rs780415568 32 dbSNP
rs369787361 33 dbSNP
rs752306101 47 dbSNP
rs562499940 58 dbSNP
rs1188919203 59 dbSNP
rs1266319098 72 dbSNP
rs1026997178 78 dbSNP
rs1002050229 84 dbSNP
rs1414665808 87 dbSNP
rs112207922 96 dbSNP
rs183591409 98 dbSNP
rs192690954 101 dbSNP
rs1291842114 102 dbSNP
rs1366922973 105 dbSNP
rs562225542 109 dbSNP
rs1200055826 113 dbSNP
rs1290404190 125 dbSNP
rs892304529 126 dbSNP
rs1052582295 150 dbSNP
rs1290554114 175 dbSNP
rs1218819288 185 dbSNP
rs936448523 188 dbSNP
rs924917803 191 dbSNP
rs1272755482 197 dbSNP
rs1050110563 201 dbSNP
rs932876028 203 dbSNP
rs1181875302 204 dbSNP
rs1415225543 206 dbSNP
rs755713546 207 dbSNP
rs1278064862 210 dbSNP
rs1349398105 216 dbSNP
rs921547531 232 dbSNP
rs1218541757 235 dbSNP
rs187648752 237 dbSNP
rs1365442723 247 dbSNP
rs1368912657 255 dbSNP
rs1409060281 263 dbSNP
rs976915641 267 dbSNP
rs577802930 272 dbSNP
rs908716616 275 dbSNP
rs983241314 277 dbSNP
rs1276342507 282 dbSNP
rs1202551777 283 dbSNP
rs1405335758 285 dbSNP
rs1482515457 286 dbSNP
rs545487917 286 dbSNP
rs1210307732 288 dbSNP
rs1238411979 295 dbSNP
rs1484416878 310 dbSNP
rs1180649352 311 dbSNP
rs34146799 315 dbSNP
rs1413674027 321 dbSNP
rs1027389259 328 dbSNP
rs564404034 331 dbSNP
rs1388616156 332 dbSNP
rs1002197232 334 dbSNP
rs969275351 346 dbSNP
rs376591374 353 dbSNP
rs185412405 356 dbSNP
rs1024810845 364 dbSNP
rs1354585361 366 dbSNP
rs200392299 378 dbSNP
rs1013464808 383 dbSNP
rs892266360 383 dbSNP
rs1413218837 384 dbSNP
rs1030852338 387 dbSNP
rs1219475690 388 dbSNP
rs575218864 390 dbSNP
rs1472464501 394 dbSNP
rs4034679 399 dbSNP
rs1314358345 401 dbSNP
rs1208420454 403 dbSNP
rs1243137155 407 dbSNP
rs1250132371 416 dbSNP
rs903630029 422 dbSNP
rs555311153 433 dbSNP
rs4034678 434 dbSNP
rs535481792 445 dbSNP
rs777131027 448 dbSNP
rs1236934802 463 dbSNP
rs867463857 464 dbSNP
rs1208137442 465 dbSNP
rs931674898 467 dbSNP
rs1437190394 468 dbSNP
rs4034677 469 dbSNP
rs1318410068 471 dbSNP
rs1363853575 481 dbSNP
rs1310304789 501 dbSNP
rs1436545651 501 dbSNP
rs1365044499 508 dbSNP
rs901510230 512 dbSNP
rs1262927332 514 dbSNP
rs573244371 518 dbSNP
rs1211159350 519 dbSNP
rs944315035 532 dbSNP
rs1199637418 535 dbSNP
rs1446553435 535 dbSNP
rs908678117 539 dbSNP
rs4034676 540 dbSNP
rs931383054 543 dbSNP
rs1412475156 553 dbSNP
rs1458570209 555 dbSNP
rs1156912500 561 dbSNP
rs752345797 564 dbSNP
rs1405511959 567 dbSNP
rs1286271282 568 dbSNP
rs1328793461 586 dbSNP
rs781004540 587 dbSNP
rs980826874 590 dbSNP
rs1411235325 592 dbSNP
rs553203240 601 dbSNP
rs2348983 602 dbSNP
rs1287051882 604 dbSNP
rs540019427 607 dbSNP
rs1301694888 616 dbSNP
rs1267317271 617 dbSNP
rs1445184936 619 dbSNP
rs1360453349 620 dbSNP
rs1337944967 622 dbSNP
rs770480465 624 dbSNP
rs992463069 632 dbSNP
rs2348982 644 dbSNP
rs1457218462 653 dbSNP
rs192929688 654 dbSNP
rs1179743079 657 dbSNP
rs956673164 657 dbSNP
rs2348981 660 dbSNP
rs1164858993 661 dbSNP
rs1410175253 662 dbSNP
rs1031240212 667 dbSNP
rs751948693 669 dbSNP
rs1308310804 674 dbSNP
rs2348980 677 dbSNP
rs746547380 680 dbSNP
rs2348979 689 dbSNP
rs1371991736 697 dbSNP
rs1412144270 709 dbSNP
rs1306549403 717 dbSNP
rs2348978 721 dbSNP
rs2348977 723 dbSNP
rs903596124 732 dbSNP
rs1246201813 737 dbSNP
rs1028707311 748 dbSNP
rs1354387111 751 dbSNP
rs1413361845 753 dbSNP
rs2348976 754 dbSNP
rs545518961 758 dbSNP
rs777111250 765 dbSNP
rs755518859 766 dbSNP
rs1249564477 767 dbSNP
rs2348975 774 dbSNP
rs944266868 789 dbSNP
rs141672473 790 dbSNP
rs750924506 796 dbSNP
rs1443527526 797 dbSNP
rs12658569 799 dbSNP
rs1168673940 801 dbSNP
rs558635285 803 dbSNP
rs887403891 815 dbSNP
rs551277507 823 dbSNP
rs1464415273 831 dbSNP
rs138981941 832 dbSNP
rs1396253114 838 dbSNP
rs920102896 843 dbSNP
rs980794662 848 dbSNP
rs576731046 851 dbSNP
rs749743605 852 dbSNP
rs188542773 868 dbSNP
rs1226505491 874 dbSNP
rs1250924336 875 dbSNP
rs1201932850 877 dbSNP
rs917899887 877 dbSNP
rs992201783 878 dbSNP
rs1460809539 884 dbSNP
rs878980796 885 dbSNP
rs956825417 886 dbSNP
rs1030956780 889 dbSNP
rs979760738 893 dbSNP
rs967838547 894 dbSNP
rs1387117212 901 dbSNP
rs1028841318 904 dbSNP
rs1469740938 907 dbSNP
rs1322900434 916 dbSNP
rs1321762332 920 dbSNP
rs1367470645 932 dbSNP
rs1454633290 943 dbSNP
rs1380582340 946 dbSNP
rs995900295 947 dbSNP
rs1331900542 948 dbSNP
rs183020062 948 dbSNP
rs1019011717 954 dbSNP
rs1209299552 957 dbSNP
rs1387903334 972 dbSNP
rs1269917406 994 dbSNP
rs747389692 1007 dbSNP
rs1185422900 1009 dbSNP
rs1434557547 1018 dbSNP
rs1425822853 1042 dbSNP
rs886108096 1043 dbSNP
rs1297062518 1045 dbSNP
rs1385899180 1046 dbSNP
rs1160619644 1059 dbSNP
rs1047277857 1060 dbSNP
rs996176657 1068 dbSNP
rs553606633 1076 dbSNP
rs898644791 1082 dbSNP
rs1246123609 1085 dbSNP
rs1045233078 1087 dbSNP
rs1344691572 1103 dbSNP
rs1228743586 1117 dbSNP
rs1290206005 1118 dbSNP
rs1486063130 1123 dbSNP
rs1326973498 1130 dbSNP
rs948127154 1140 dbSNP
rs918036246 1142 dbSNP
rs1480338456 1144 dbSNP
rs1489151733 1144 dbSNP
rs35630308 1144 dbSNP
rs397705358 1144 dbSNP
rs1056864893 1153 dbSNP
rs1414914496 1181 dbSNP
rs1218881958 1193 dbSNP
rs1361189748 1197 dbSNP
rs1369162814 1217 dbSNP
rs935306349 1223 dbSNP
rs528890331 1233 dbSNP
rs879941578 1246 dbSNP
rs780529729 1251 dbSNP
rs1410266199 1259 dbSNP
rs979342093 1262 dbSNP
rs1370821933 1265 dbSNP
rs145092214 1271 dbSNP
rs1323050740 1274 dbSNP
rs921744000 1277 dbSNP
rs1290667990 1279 dbSNP
rs1300431727 1283 dbSNP
rs974601198 1287 dbSNP
rs1254426569 1293 dbSNP
rs1479842004 1295 dbSNP
rs965785202 1306 dbSNP
rs1018658427 1309 dbSNP
rs1005050473 1334 dbSNP
rs1161730268 1344 dbSNP
rs141447191 1345 dbSNP
rs138453445 1351 dbSNP
rs995697691 1353 dbSNP
rs1352568004 1358 dbSNP
rs1441179054 1365 dbSNP
rs1366447583 1366 dbSNP
rs533796898 1373 dbSNP
rs1449907853 1379 dbSNP
rs1427901118 1386 dbSNP
rs1313757308 1387 dbSNP
rs1342170558 1388 dbSNP
rs190091171 1396 dbSNP
rs1045202565 1406 dbSNP
rs1012407985 1413 dbSNP
rs1204258569 1428 dbSNP
rs143659796 1431 dbSNP
rs1484531827 1437 dbSNP
rs1182210584 1438 dbSNP
rs1266355920 1440 dbSNP
rs1450112064 1442 dbSNP
rs1393082133 1489 dbSNP
rs370106248 1489 dbSNP
rs1176508658 1494 dbSNP
rs375756725 1494 dbSNP
rs1490721576 1495 dbSNP
rs1468175391 1497 dbSNP
rs370789643 1497 dbSNP
rs1365328999 1498 dbSNP
rs1436622307 1499 dbSNP
rs1268114584 1500 dbSNP
rs186955834 1502 dbSNP
rs1219386738 1504 dbSNP
rs1279784951 1505 dbSNP
rs750722420 1506 dbSNP
rs962608061 1508 dbSNP
rs1016299818 1521 dbSNP
rs561653813 1527 dbSNP
rs946601848 1532 dbSNP
rs1006214458 1533 dbSNP
rs958792547 1549 dbSNP
rs1240639058 1552 dbSNP
rs1475217684 1558 dbSNP
rs541783468 1558 dbSNP
rs1228744262 1560 dbSNP
rs974661888 1564 dbSNP
rs965835719 1572 dbSNP
rs115790612 1593 dbSNP
rs1175684927 1604 dbSNP
rs1389276921 1606 dbSNP
rs866894695 1610 dbSNP
rs1315624896 1619 dbSNP
rs1344021521 1621 dbSNP
rs1436790219 1622 dbSNP
rs1388895351 1625 dbSNP
rs1276200227 1627 dbSNP
rs553408640 1629 dbSNP
rs1003125448 1632 dbSNP
rs907066427 1635 dbSNP
rs1222030600 1641 dbSNP
rs1027309395 1643 dbSNP
rs1346615304 1656 dbSNP
rs546013094 1659 dbSNP
rs962930843 1666 dbSNP
rs577280653 1671 dbSNP
rs893028933 1672 dbSNP
rs1054062629 1683 dbSNP
rs545603472 1689 dbSNP
rs910973989 1690 dbSNP
rs1222620228 1704 dbSNP
rs866426269 1707 dbSNP
rs1462385909 1708 dbSNP
rs933728672 1715 dbSNP
rs1471121070 1719 dbSNP
rs537645289 1733 dbSNP
rs1377012425 1735 dbSNP
rs923503681 1741 dbSNP
rs972625308 1743 dbSNP
rs1325162007 1747 dbSNP
rs1173610861 1750 dbSNP
rs1481292425 1755 dbSNP
rs1269396964 1756 dbSNP
rs1180967468 1773 dbSNP
rs1302938540 1773 dbSNP
rs1241849400 1774 dbSNP
rs1481886961 1786 dbSNP
rs1350113740 1790 dbSNP
rs568728328 1793 dbSNP
rs555341037 1802 dbSNP
rs909437043 1807 dbSNP
rs535429837 1809 dbSNP
rs958658564 1819 dbSNP
rs1439286727 1822 dbSNP
rs1034341525 1827 dbSNP
rs1232202384 1828 dbSNP
rs1472878771 1829 dbSNP
rs1164921409 1836 dbSNP
rs1382791223 1851 dbSNP
rs1002997146 1852 dbSNP
rs566374313 1867 dbSNP
rs546659707 1868 dbSNP
rs532854279 1879 dbSNP
rs1226752276 1882 dbSNP
rs1337773834 1883 dbSNP
rs112177450 1889 dbSNP
rs182294996 1890 dbSNP
rs1010456874 1892 dbSNP
rs1357318353 1895 dbSNP
rs1245547447 1896 dbSNP
rs1249748654 1899 dbSNP
rs1395529765 1904 dbSNP
rs367781626 1905 dbSNP
rs900512726 1907 dbSNP
rs569387071 1909 dbSNP
rs1038943441 1910 dbSNP
rs530629989 1913 dbSNP
rs1032852227 1914 dbSNP
rs1442947656 1918 dbSNP
rs561640239 1922 dbSNP
rs1400239687 1924 dbSNP
rs944626779 1925 dbSNP
rs541785129 1933 dbSNP
rs757512544 1941 dbSNP
rs1188864174 1946 dbSNP
rs1429685685 1947 dbSNP
rs528468705 1948 dbSNP
rs920379918 1966 dbSNP
rs1365192188 1983 dbSNP
rs1470605345 1985 dbSNP
rs973129101 1987 dbSNP
rs969660230 1998 dbSNP
rs1050716218 2006 dbSNP
rs1298697865 2014 dbSNP
rs1328411622 2023 dbSNP
rs1225444935 2046 dbSNP
rs991008246 2052 dbSNP
rs1345406457 2054 dbSNP
rs1441326542 2055 dbSNP
rs1253530728 2057 dbSNP
rs777591181 2061 dbSNP
rs11135442 2064 dbSNP
rs1208808942 2067 dbSNP
rs1263486880 2073 dbSNP
rs1036547721 2090 dbSNP
rs1191973119 2106 dbSNP
rs546198083 2107 dbSNP
rs1372889726 2112 dbSNP
rs1480954245 2117 dbSNP
rs747664416 2121 dbSNP
rs780914796 2128 dbSNP
rs937572755 2133 dbSNP
rs1022356515 2137 dbSNP
rs1011010658 2159 dbSNP
rs573506851 2161 dbSNP
rs927300768 2171 dbSNP
rs145706923 2177 dbSNP
rs1331520922 2178 dbSNP
rs971518146 2189 dbSNP
rs1353031207 2192 dbSNP
rs76341619 2197 dbSNP
rs1281377866 2198 dbSNP
rs557499888 2202 dbSNP
rs79563493 2210 dbSNP
rs76170229 2211 dbSNP
rs1202021905 2212 dbSNP
rs1262004239 2212 dbSNP
rs397749285 2212 dbSNP
rs574431618 2212 dbSNP
rs59178277 2212 dbSNP
rs879205799 2212 dbSNP
rs1244409899 2213 dbSNP
rs1039080023 2214 dbSNP
rs988663253 2214 dbSNP
rs1338747112 2215 dbSNP
rs1317293186 2218 dbSNP
rs1454463739 2221 dbSNP
rs1451698208 2222 dbSNP
rs1288555259 2224 dbSNP
rs1366426820 2229 dbSNP
rs944627186 2230 dbSNP
rs957168441 2232 dbSNP
rs890403103 2248 dbSNP
rs1391913350 2249 dbSNP
rs1309027918 2254 dbSNP
rs1032799824 2260 dbSNP
rs1237694091 2265 dbSNP
rs1265722001 2276 dbSNP
rs1361156956 2283 dbSNP
rs1219725791 2292 dbSNP
rs754663573 2294 dbSNP
rs11135441 2298 dbSNP
rs1178323955 2302 dbSNP
rs1253257158 2308 dbSNP
rs889682336 2314 dbSNP
rs763006991 2319 dbSNP
rs920446947 2321 dbSNP
rs1385865390 2327 dbSNP
rs1426819184 2331 dbSNP
rs1472282467 2335 dbSNP
rs1037383878 2349 dbSNP
rs1184920616 2354 dbSNP
rs575131589 2357 dbSNP
rs1299877174 2358 dbSNP
rs1371090175 2362 dbSNP
rs1390683944 2368 dbSNP
rs1029360685 2376 dbSNP
rs1384301035 2384 dbSNP
rs998232889 2416 dbSNP
rs992480081 2418 dbSNP
rs17085231 2419 dbSNP
rs1205644172 2427 dbSNP
rs1207465045 2435 dbSNP
rs1479944606 2436 dbSNP
rs78083848 2440 dbSNP
rs1243861761 2442 dbSNP
rs1446492444 2455 dbSNP
rs750886934 2462 dbSNP
rs1182034897 2463 dbSNP
rs978376496 2472 dbSNP
rs887982987 2484 dbSNP
rs765741086 2492 dbSNP
rs1172278351 2495 dbSNP
rs1049238446 2499 dbSNP
rs1461440945 2501 dbSNP
rs1022491903 2508 dbSNP
rs1293969508 2514 dbSNP
rs1407709202 2517 dbSNP
rs937605382 2528 dbSNP
rs927499354 2533 dbSNP
rs113062985 2534 dbSNP
rs370623559 2534 dbSNP
rs1017609791 2539 dbSNP
rs1215889867 2545 dbSNP
rs981484548 2549 dbSNP
rs1428612081 2556 dbSNP
rs1298198764 2558 dbSNP
rs1009353523 2578 dbSNP
rs950052407 2582 dbSNP
rs1327951334 2583 dbSNP
rs762377274 2600 dbSNP
rs1198620016 2606 dbSNP
rs1264281429 2617 dbSNP
rs890465114 2618 dbSNP
rs1242543506 2629 dbSNP
rs556026482 2631 dbSNP
rs1188457329 2634 dbSNP
rs913324762 2635 dbSNP
rs989335724 2641 dbSNP
rs753905070 2642 dbSNP
rs1363340016 2650 dbSNP
rs753864826 2654 dbSNP
rs1431332405 2665 dbSNP
rs1467832559 2668 dbSNP
rs1424737643 2685 dbSNP
rs576218753 2689 dbSNP
rs1032831068 2696 dbSNP
rs566379546 2698 dbSNP
rs1432479879 2704 dbSNP
rs1389078601 2705 dbSNP
rs764212635 2707 dbSNP
rs1286729183 2710 dbSNP
rs760851890 2717 dbSNP
rs1360378921 2718 dbSNP
rs953978255 2719 dbSNP
rs1218400023 2720 dbSNP
rs115177781 2722 dbSNP
rs1222160513 2723 dbSNP
rs191147341 2726 dbSNP
rs867859198 2727 dbSNP
rs1198614302 2730 dbSNP
rs187133993 2736 dbSNP
rs1271318205 2743 dbSNP
rs1487872466 2745 dbSNP
rs570174011 2745 dbSNP
rs915693423 2745 dbSNP
rs141074513 2746 dbSNP
rs1479421809 2753 dbSNP
rs550303247 2768 dbSNP
rs1056796147 2776 dbSNP
rs1401920729 2785 dbSNP
rs1156568077 2786 dbSNP
rs879045258 2787 dbSNP
rs938306246 2788 dbSNP
rs924315852 2795 dbSNP
rs1212691336 2798 dbSNP
rs1347720139 2800 dbSNP
rs1403672291 2802 dbSNP
rs978728070 2808 dbSNP
rs1015255001 2810 dbSNP
rs967012590 2811 dbSNP
rs536846022 2812 dbSNP
rs1225526720 2816 dbSNP
rs1282501066 2822 dbSNP
rs888182406 2842 dbSNP
rs1353261704 2853 dbSNP
rs1270493506 2860 dbSNP
rs989681548 2862 dbSNP
rs964787734 2865 dbSNP
rs1489776444 2874 dbSNP
rs1017663527 2876 dbSNP
rs1008992816 2878 dbSNP
rs796974881 2883 dbSNP
rs1470918074 2885 dbSNP
rs1049271427 2893 dbSNP
rs1001679322 2899 dbSNP
rs954842635 2911 dbSNP
rs770707970 2919 dbSNP
rs1046370875 2920 dbSNP
rs1424930343 2922 dbSNP
rs950323074 2925 dbSNP
rs567945916 2927 dbSNP
rs1367894405 2930 dbSNP
rs1026331909 2931 dbSNP
rs1336864666 2933 dbSNP
rs1304565545 2934 dbSNP
rs566712121 2935 dbSNP
rs1053031652 2936 dbSNP
rs899116623 2941 dbSNP
rs936117244 2946 dbSNP
rs1294177350 2953 dbSNP
rs1357089955 2955 dbSNP
rs1012740210 2958 dbSNP
rs926012154 2961 dbSNP
rs1439507982 2967 dbSNP
rs985280245 2968 dbSNP
rs1237066469 2969 dbSNP
rs1444686664 2982 dbSNP
rs776364281 2994 dbSNP
rs922555378 2995 dbSNP
rs977111058 2997 dbSNP
rs1420856500 3007 dbSNP
rs1172575953 3015 dbSNP
rs182256130 3016 dbSNP
rs1397583234 3025 dbSNP
rs902832239 3031 dbSNP
rs1015702152 3034 dbSNP
rs1271567431 3035 dbSNP
rs1200376821 3041 dbSNP
rs557523519 3042 dbSNP
rs1005192444 3043 dbSNP
rs1482872046 3046 dbSNP
rs1041413978 3047 dbSNP
rs1380865321 3049 dbSNP
rs952457219 3063 dbSNP
rs1033390370 3066 dbSNP
rs1270575688 3069 dbSNP
rs1001710664 3079 dbSNP
rs945602858 3081 dbSNP
rs1194046167 3086 dbSNP
rs906060243 3093 dbSNP
rs915536030 3109 dbSNP
rs1045898411 3118 dbSNP
rs1461423416 3121 dbSNP
rs1205011238 3139 dbSNP
rs1249645555 3145 dbSNP
rs770605061 3146 dbSNP
rs1441498741 3151 dbSNP
rs559601195 3158 dbSNP
rs1439418866 3162 dbSNP
rs763833889 3163 dbSNP
rs1476574161 3164 dbSNP
rs989735352 3173 dbSNP
rs191683053 3175 dbSNP
rs1423538665 3177 dbSNP
rs1470553700 3178 dbSNP
rs769849019 3193 dbSNP
rs943484897 3194 dbSNP
rs1395703164 3199 dbSNP
rs1319194237 3201 dbSNP
rs1328032635 3209 dbSNP
rs910732999 3210 dbSNP
rs1277563833 3223 dbSNP
rs987936522 3229 dbSNP
rs1225203718 3231 dbSNP
rs1285001871 3235 dbSNP
rs1043381 3238 dbSNP
rs1482620410 3245 dbSNP
rs1349510826 3249 dbSNP
rs892035586 3256 dbSNP
rs1026720485 3257 dbSNP
rs776258710 3260 dbSNP
rs1295881540 3261 dbSNP
rs1053063797 3269 dbSNP
rs1443736873 3274 dbSNP
rs935981394 3275 dbSNP
rs1191964257 3298 dbSNP
rs926044699 3318 dbSNP
rs1262851739 3319 dbSNP
rs1351848369 3322 dbSNP
rs1049768544 3323 dbSNP
rs112008372 3324 dbSNP
rs932747394 3326 dbSNP
rs1334063061 3332 dbSNP
rs1179161944 3343 dbSNP
rs922448867 3344 dbSNP
rs1465589324 3353 dbSNP
rs1159424197 3354 dbSNP
rs186809825 3357 dbSNP
rs961603098 3360 dbSNP
rs1398312071 3361 dbSNP
rs908431445 3363 dbSNP
rs1345855809 3364 dbSNP
rs1308225531 3366 dbSNP
rs1177625646 3368 dbSNP
rs983790508 3370 dbSNP
rs1472351490 3397 dbSNP
rs1281265834 3399 dbSNP
rs1311152245 3420 dbSNP
rs35457589 3420 dbSNP
rs1239118435 3428 dbSNP
rs1261905688 3429 dbSNP
rs746624629 3447 dbSNP
rs1215380377 3452 dbSNP
rs952322975 3453 dbSNP
rs1033338004 3454 dbSNP
rs1285795309 3457 dbSNP
rs7918 3459 dbSNP
rs1490607249 3466 dbSNP
rs779588109 3470 dbSNP
rs543963052 3474 dbSNP
rs530081747 3475 dbSNP
rs1209297479 3482 dbSNP
rs1459949088 3489 dbSNP
rs370672982 3504 dbSNP
rs575072466 3514 dbSNP
rs771474169 3515 dbSNP
rs1328301508 3518 dbSNP
rs1014396318 3519 dbSNP
rs749838541 3520 dbSNP
rs561611053 3524 dbSNP
rs1031846959 3528 dbSNP
rs1366828851 3532 dbSNP
rs1225169027 3539 dbSNP
rs1373394373 3551 dbSNP
rs1283129106 3554 dbSNP
rs1451039951 3577 dbSNP
rs550891967 3579 dbSNP
rs974511522 3581 dbSNP
rs1000162146 3586 dbSNP
rs1373965866 3588 dbSNP
rs1239029563 3607 dbSNP
rs779311219 3614 dbSNP
rs1360691734 3620 dbSNP
rs1225182780 3621 dbSNP
rs1263976642 3639 dbSNP
rs1488447145 3648 dbSNP
rs1196837060 3652 dbSNP
rs904569291 3654 dbSNP
rs1049696450 3655 dbSNP
rs932755871 3668 dbSNP
rs1041774163 3684 dbSNP
rs1446287930 3695 dbSNP
rs946997121 3702 dbSNP
rs1161524249 3703 dbSNP
rs1462464919 3708 dbSNP
rs561291854 3711 dbSNP
rs1054013177 3712 dbSNP
rs541632615 3719 dbSNP
rs1445389771 3722 dbSNP
rs1315390314 3723 dbSNP
rs943619066 3734 dbSNP
rs142416372 3737 dbSNP
rs1311057693 3740 dbSNP
rs1321455424 3752 dbSNP
rs1181847672 3753 dbSNP
rs1260523733 3760 dbSNP
rs147620971 3771 dbSNP
rs908467784 3773 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166 , TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000237853.4 | 3UTR | AUAUUUAACCAUAACAUACUGUGAUUCAUCAAACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000237853.4 | 3UTR | AUAUAUUUAACCAUAACAUACUGUGAUUCAUCAAACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
62 hsa-miR-758-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT085323 MORC3 MORC family CW-type zinc finger 3 2 2
MIRT089441 STAMBP STAM binding protein 2 2
MIRT089456 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT111856 CCND1 cyclin D1 2 2
MIRT184933 ZNF268 zinc finger protein 268 2 2
MIRT215288 CREBRF CREB3 regulatory factor 2 2
MIRT237300 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT238446 MYO10 myosin X 2 4
MIRT273827 RPL41 ribosomal protein L41 2 2
MIRT282703 HOOK1 hook microtubule tethering protein 1 2 2
MIRT347970 ZNF850 zinc finger protein 850 2 2
MIRT371076 KLF3 Kruppel like factor 3 2 2
MIRT464339 USP6NL USP6 N-terminal like 2 2
MIRT470034 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT477506 ELL2 elongation factor for RNA polymerase II 2 2 2
MIRT482886 CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 2 2
MIRT492606 POLR3E RNA polymerase III subunit E 2 2
MIRT502294 GNG12 G protein subunit gamma 12 2 6
MIRT507600 DCTN4 dynactin subunit 4 2 4
MIRT510728 SON SON DNA binding protein 2 6
MIRT514065 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 8
MIRT519718 ZNF512B zinc finger protein 512B 2 4
MIRT520890 STRN striatin 2 2
MIRT521760 PPIL1 peptidylprolyl isomerase like 1 2 6
MIRT526874 ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2 2
MIRT530232 WSB2 WD repeat and SOCS box containing 2 2 2
MIRT532003 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT533371 UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 2 4
MIRT547106 PIGW phosphatidylinositol glycan anchor biosynthesis class W 2 2
MIRT548189 FOXA1 forkhead box A1 2 2
MIRT552935 VKORC1L1 vitamin K epoxide reductase complex subunit 1 like 1 2 2
MIRT560085 ZNF195 zinc finger protein 195 2 2
MIRT561726 PPP2CA protein phosphatase 2 catalytic subunit alpha 2 2
MIRT562713 ZNF415 zinc finger protein 415 2 2
MIRT562761 ZNF846 zinc finger protein 846 2 2
MIRT564159 ZNF117 zinc finger protein 117 2 2
MIRT565673 SETD5 SET domain containing 5 2 2
MIRT565718 SESN3 sestrin 3 2 2
MIRT566026 RFX1 regulatory factor X1 2 2
MIRT569048 ZNF655 zinc finger protein 655 2 2
MIRT570367 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT570410 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT570443 TMEM189 transmembrane protein 189 2 2
MIRT571738 RNF11 ring finger protein 11 2 2
MIRT575042 Tpgs2 tubulin polyglutamylase complex subunit 2 2 4
MIRT614330 ZDHHC22 zinc finger DHHC-type containing 22 2 2
MIRT617629 RAB3IP RAB3A interacting protein 2 2
MIRT621667 UBE4B ubiquitination factor E4B 2 2
MIRT639906 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2 2
MIRT651436 XRCC5 X-ray repair cross complementing 5 2 2
MIRT683853 ZNF208 zinc finger protein 208 2 2
MIRT684841 TPGS2 tubulin polyglutamylase complex subunit 2 2 5
MIRT689347 ZNF83 zinc finger protein 83 2 2
MIRT692492 SPIN4 spindlin family member 4 2 2
MIRT695711 OLA1 Obg like ATPase 1 2 2
MIRT698219 TMEM248 transmembrane protein 248 2 2
MIRT711560 FAM20B FAM20B, glycosaminoglycan xylosylkinase 2 2
MIRT712867 TMEM67 transmembrane protein 67 2 2
MIRT722956 TSPAN1 tetraspanin 1 2 2
MIRT723622 SOBP sine oculis binding protein homolog 2 2
MIRT724176 ABCF2 ATP binding cassette subfamily F member 2 2 2
MIRT755363 LMBR1 limb development membrane protein 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-758 Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-758 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-758 5-Fluorouracil approved 3385 Quantitative real-time PCR human squamous cell carcinoma cell line KYSE410 21743970 2011 up-regulated
miR-758 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-758 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-mir-758 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-758-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-758-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-758-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-758-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-758-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-758-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-758-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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