miRTarBase - #MIRT478953


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pre-miRNA Information
pre-miRNA hsa-mir-3179-1   
Genomic Coordinates chr16: 14901508 - 14901591
Description Homo sapiens miR-3179-1 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-2   
Genomic Coordinates chr16: 16300159 - 16300242
Description Homo sapiens miR-3179-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-3   
Genomic Coordinates chr16: 18411894 - 18411977
Description Homo sapiens miR-3179-3 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-4   
Genomic Coordinates chr16: 18494493 - 18494576
Description Homo sapiens miR-3179-4 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-3179
Sequence 52| AGAAGGGGUGAAAUUUAAACGU |73
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1351100204 1 dbSNP
rs1398613616 4 dbSNP
rs1340262765 20 dbSNP
rs1229893475 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol COX15   
Synonyms CEMCOX2
Description COX15, cytochrome c oxidase assembly homolog
Transcript NM_078470   
Other Transcripts NM_004376   
Expression
Putative miRNA Targets on COX15
3'UTR of COX15
(miRNA target sites are highlighted)		 
>COX15|NM_078470|3'UTR
   1 TTCTTAGAGGACCAGCCTCCTGGGACTGTGACTGCTTTTGAGAGCTCTTCAGAGATCATAAGAACTTGGGCTTTTCTACG
  81 AGATGACCTTGACATACCAAGTGGTTTCCAAATGGTCAACTTACTTAAAAATCTTTTCCTGTTTTGAGATAGTCACTGGA
 161 TCAAGAATGCATTAAGTGTGGTTACCCTAAATGTTCCCTTTTAAATCTGCTTTTCATGTTGAAAATCAGTTTTAATGTAG
 241 AGAAAGAAATGTCTGCCATTTGCTGCTTAACAGGCTTTGTGTCAGGTTTTTCAGTGTTGGCAAGCTCTTGGTTCTACGTG
 321 GATGATTTCTACGTGGATGTTCTCCTGAGTCCTTAATTCTGCCTAAATAGAATTTCTTTATGATCTTAACTTCACTTCCA
 401 TTAGGTGAAGATTGAAAGGATAGGATTGACATACCCAAAGTAGCCAGCTGGTCTTCAGCAAAAAAAAAAAAGCTAATGTC
 481 TTCTAATATCCTGATTTTCAGAAATGGGGAAATTGCAGATTTTGACAAGCTTAATGTGTATATGTAGCAAAATGGTTTTT
 561 AAGTACTTGGAAAAGGAGGTAATCGCCAAATAGTTCCATTTTTTTTTTTTTTTTTGAGACAGAGTTTCACTCTTGTTGCC
 641 CAGGCTGGAGTACAATGGCGTGATCTCAGCTCACTCTGCAACCTCCACTTCCCAGGTTCAAGCGATTCTCATGCCTCAGC
 721 CTCCCGAGTAGCTGGGACTACAGGCACAAGTCACCATGCCTGGCTAATTTTGTATTTTTAGTAGAGAAGGGGTTTCACCA
 801 CATTGGCCGGGCTGGTCTTGAACTCCTGACCTCAGGTAATCCGCCCATCTCGGCTTCCCAAAGTGCTGAGATTACAGGCA
 881 TGGGCCACCACGCCCAGCTAGTTCCTCTTTTGATAAGGCTGTTAACATTACAAGGTCAGAGAGAGGAATGGAATCGACAG
 961 TATAAATTGGTTCCTGAGAGGGTTTCCTAACAGCTTTGTAATAAGAAAAATATGGCCTTGATGGTGTAGTGCATGGACAT
1041 CTACCCAGATAAACAAATTGTTGACTGCTGAATTAATGTGATTTTGGTCTCTATTGATATTTCATAGGGCCCTGTCTTAT
1121 TCAACTTTACTTTTAAAATCAGTGATTTGGATGAAGGCATCAGAAACATCTGATTTGAGGATGGAGCAACCCAATATTGC
1201 TAATATAATAGATGACAGTGGCAACTGAAAACAGTCCCAGAATGACCCCATCGAGATGAAATTAAACAGATTAGAAATGT
1281 AACATACTCATTTAAATTAAATAAGTTGTATAAGTTTGGGCTGAAGAAACCTGGCCTTATATCATTTCATATAAAAAAGA
1361 CGGGATTTTAGTTGTCCTCAGGTTCAATATGAACCAAGTAGTATTCATGTTGTTATTATATGATAACAGAAAAATTAGTG
1441 GTACTTCAGGTTTTATCAGTAGAAGTGTCACAGCCATAGTCAAAATACCCCTAACATACTGCATTTCACTCTGGGTACCA
1521 AATTTAAGCAAGATATTGATGGCCACTAAGTGTGTATCCAGAAGAAGAGATCAGAATGATGAGTCCAGAACCCCTGTCAC
1601 ACAGGGAATAGGTGAAGGAACTAGGGATATTTAACTGGAGCAGAGAACATCTGGAGAGAGAGCAAGATTCCTGTCCTTGA
1681 GAAGTTGAAGCCGTCTCATGCAGAAGAGGGAATGAGCTTCCATTATGCTGCAGAGCTGGCAGCAATGGATGAAAGTTGCA
1761 GGAAGTTAGTTTTAGTTCTGTAGAAGGCAAGAGTAGGGTAGACCAAATCAAATGCTCACTGGGGTCAGGCTGATGGAGAC
1841 AGTAACACTGGCGAGCAGGTGCCCCAGCTCGGACTATACTGCTGAGTTCTGGTCTGTTGCTGCCACTCTACAGGTCCAGG
1921 GTTGTTAGATCTTCTGGGTTTTTGTTTTGCTTTTTGAAATAAGGAAAATAAGCTTATCTTAAGTTTATTTTTCCTTGGAT
2001 ATACCTAGATTCCATACAGTGACAATACAAATACAAAGGAAGAACATCTGGATTTCATCCTTGACCTCATTTACAAAGCA
2081 AAAAGAGATGCTGGATTCAGATATAAATGTTTAATTTTGCAGTGTTTAAGTCAGCAAATCTTCTGTTTTTTAAAAATAAG
2161 CCACATATCTAGATTTTTCTGTGAAAGCTCTCAATTAAGTGTTGGGAACTAATTTCAAGATTTTAAAAAATGTTATGCAG
2241 GCTTAACGTGTCTGAGAGCCATAAATGACCTAACGTTTCCCGTTAGTCTCTGAACTAGGTGATCTCAGTTCTCTTTCAAC
2321 TCCAGTACTCTGTAAGTTTCTGTGACCTGTAGTGTACCATTCTCAGGTGGTGATATGGTTTGGATGTTTTGTCCCCTCCA
2401 AATCTCATGTTCAAAGTGTGACATTCAGTGTTAGAGGTGGGCCTAGTAGGAGGTATTTGGGTCATGGGGGCGGATCCCTT
2481 ATGTATGACTTTGTGCCATCCCCATAGTAATGAGTGAGTTCTCACTCTGGTTGTTTATGCAAGAGCTGGTTGTTTAAAAG
2561 AGCCTGGAACTTCCTCCTCTCTCGCTTGCTCTCTCTCACCATGTGACACACTGGCTCCCCTTCACCTTCTGCCATGATTG
2641 TAAGCTTCGTGAGGCCCTCACCAGAAGCAGATGCCAGCGCCATGCTTCCTATACAGTTCTATGCAGAACAGTGAGCCAAA
2721 TAAACCTCTTTTCTTTCTAAAAATTGTCAGTATTTCCTTATAGCAATGCAAGCCGACTAACACAGGTGATTCTTAGCAAA
2801 ACAGTTTGTCAATTTTTCATAAATGCTGGACCCTGGCTGGGCTTATGCTATTGCCTAGAAGAGATTCCCAACTTCTCTCT
2881 TATTTGAATCTTAGAAAAATCCCAAAGCCCAAGCCTCATCTAAGACCAATTAAGTCACAATCCCTGGAGGAAGTAAAAGG
2961 CATATTTTTAAAGTTCCCCAGGTGATTCCAATGTGCAGACAAGTCTAGGGACCACTGGCTTAGGTCCTAATAGCCTAGTT
3041 ACCTTAGAAAGTTCTGACTAGCTTATTCCCATTCCCTTCTAATTTCCACCCCACCTTATCATTTGATCTGCTATGTTGCT
3121 CCTATTAGTATGTTAGTAGGATATGGTCTCTTCTGGATAGAATCCTTCAAAGAAAGGGAACTGTAGTTCCTGAGGCAGGT
3201 TCCCACACCATCCTCTCCTGATCCTCAAACCCAGGTTGTCCTTAGTTAGTAACTGAGTCAGCAGAGGGCAGTATGACCCA
3281 ACCCAAAGAACCATATATTAATGCTTCTACAGTTGCCTCCAAGGAAGTAGCAACTCATGAGTAAGTTAAGGTTTCAGATG
3361 TTTTACTTCATTTTTCTTTTATTACAGATGATGAGTACATTTGGAAAAACAACTGGTTGCATTTAGCTATATAACTGTAT
3441 TATATCTATGAGCTTCTGGTGAATGATTATCTTAGGGTTTTTTTTGTATTTATGTTATTCCCAGCACTCCCAGACACATA
3521 TCAAATATTGAATTAGTGAATGCATGAATGGAAAATGGATAATTACAGATTGATGTTCCAAATACCTTTTTCCAAAAAAA
3601 CAAGTCATCACATACCTATAGGATTAAATAGATTTCCCTTAATATTTTCAAAGGTCTCTCTGCACTTACGTCCATTGTTT
3681 TTAAAACATGAAGGAAATTAAAACACATGGCTTTCTTAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugcaaauUUAAAGUGGGGAAGa 5'
                 | |  | ||||||| 
Target 5' gtgacacACTGGCTCCCCTTCa 3'
 2603 - 2624 143.00 -12.20
2 
miRNA  3' ugCAAAUUU--AAAGU-GGGGAAGa 5'
            ||||::|  |||:: ||||| | 
Target 5' tgGTTTGGATGTTTTGTCCCCTCCa 3'
 2376 - 2400 134.00 -12.60
3 
miRNA  3' ugCAAAUUUAA-AGU-GGGGAAGa 5'
            | ||  |||  || :|||||| 
Target 5' taGCTT--ATTCCCATTCCCTTCt 3'
 3059 - 3080 132.00 -11.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1201693 316 ClinVar
683434 809 ClinVar
298412 1122 ClinVar
128836 1126 ClinVar
298411 1197 ClinVar
878697 1242 ClinVar
298410 1309 ClinVar
878696 1349 ClinVar
298409 1361 ClinVar
878695 1362 ClinVar
298408 1431 ClinVar
298407 1474 ClinVar
878694 1590 ClinVar
878693 1591 ClinVar
298406 1594 ClinVar
298405 1693 ClinVar
298404 1716 ClinVar
298403 1776 ClinVar
298402 1793 ClinVar
298401 1850 ClinVar
298400 1851 ClinVar
877675 1876 ClinVar
880433 1957 ClinVar
298399 2060 ClinVar
880432 2167 ClinVar
298398 2193 ClinVar
298397 2282 ClinVar
880430 2301 ClinVar
880431 2301 ClinVar
298396 2459 ClinVar
298395 2490 ClinVar
879245 2594 ClinVar
879244 2595 ClinVar
879243 2620 ClinVar
298394 2649 ClinVar
298393 2668 ClinVar
298392 2701 ClinVar
879242 2745 ClinVar
298391 2756 ClinVar
878646 2839 ClinVar
878645 2850 ClinVar
298390 2857 ClinVar
298389 2898 ClinVar
878644 2959 ClinVar
298388 3247 ClinVar
878643 3362 ClinVar
298387 3417 ClinVar
298385 3486 ClinVar
298386 3486 ClinVar
877634 3638 ClinVar
298384 3670 ClinVar
COSN30125739 20 COSMIC
COSN19663253 23 COSMIC
COSN30136823 49 COSMIC
COSN30516072 91 COSMIC
COSN30543328 159 COSMIC
COSN31600078 165 COSMIC
COSN28986113 460 COSMIC
COSN1110964 492 COSMIC
COSN16866308 725 COSMIC
COSN31960532 956 COSMIC
COSN30536289 1009 COSMIC
COSN31603962 1015 COSMIC
COSN30454146 1048 COSMIC
COSN28750055 1061 COSMIC
COSM7526718 1155 COSMIC
COSM8169390 1165 COSMIC
COSN30145575 1177 COSMIC
COSN31614107 1205 COSMIC
COSN30180246 1210 COSMIC
COSN28424356 1215 COSMIC
COSN30477471 1220 COSMIC
COSN18734770 1253 COSMIC
COSN31580669 1269 COSMIC
COSN17182226 1280 COSMIC
COSN30501159 1288 COSMIC
COSN30543881 1335 COSMIC
COSN30497407 1357 COSMIC
COSN30497120 1405 COSMIC
COSN27954778 2555 COSMIC
COSN26615992 2610 COSMIC
COSN1466483 2736 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs774848108 4 dbSNP
rs533184828 7 dbSNP
rs893167777 10 dbSNP
rs1422741626 12 dbSNP
rs769129948 13 dbSNP
rs187834743 21 dbSNP
rs1031629521 24 dbSNP
rs368724833 26 dbSNP
rs1418309809 27 dbSNP
rs1423671888 28 dbSNP
rs1406018110 31 dbSNP
rs779894822 31 dbSNP
rs998930038 40 dbSNP
rs1162945397 44 dbSNP
rs775826954 46 dbSNP
rs770105479 47 dbSNP
rs756347746 54 dbSNP
rs1295319182 58 dbSNP
rs1347356956 72 dbSNP
rs577370211 74 dbSNP
rs1477289235 78 dbSNP
rs1277399311 79 dbSNP
rs1277384449 80 dbSNP
rs1198258555 94 dbSNP
rs1216037302 96 dbSNP
rs1287317937 104 dbSNP
rs1051576333 108 dbSNP
rs1320690602 109 dbSNP
rs1221699409 110 dbSNP
rs1266660854 118 dbSNP
rs552769230 119 dbSNP
rs1260777005 124 dbSNP
rs1241554473 128 dbSNP
rs1376803045 130 dbSNP
rs932518024 132 dbSNP
rs899633120 134 dbSNP
rs1454860850 136 dbSNP
rs1038322425 137 dbSNP
rs913415402 138 dbSNP
rs989350767 144 dbSNP
rs540891515 148 dbSNP
rs1413378747 152 dbSNP
rs573862490 168 dbSNP
rs941242672 175 dbSNP
rs750637877 178 dbSNP
rs183099521 187 dbSNP
rs1341330300 188 dbSNP
rs1406133791 191 dbSNP
rs957648457 195 dbSNP
rs1333696956 205 dbSNP
rs1417850369 213 dbSNP
rs1297504859 215 dbSNP
rs1340986517 216 dbSNP
rs982437774 237 dbSNP
rs1394489887 240 dbSNP
rs938982807 245 dbSNP
rs1432663869 246 dbSNP
rs1282171671 247 dbSNP
rs767534714 254 dbSNP
rs112354052 257 dbSNP
rs1419087202 269 dbSNP
rs996429493 271 dbSNP
rs191301593 275 dbSNP
rs1287385209 281 dbSNP
rs1018877322 285 dbSNP
rs1237236366 286 dbSNP
rs556480730 294 dbSNP
rs377068774 296 dbSNP
rs564417512 302 dbSNP
rs1378621661 308 dbSNP
rs1439176916 314 dbSNP
rs115979585 316 dbSNP
rs796678570 317 dbSNP
rs188062046 318 dbSNP
rs1358346765 322 dbSNP
rs994444450 332 dbSNP
rs117493763 333 dbSNP
rs1374129279 334 dbSNP
rs776219862 336 dbSNP
rs1038723654 337 dbSNP
rs937257506 342 dbSNP
rs763489824 345 dbSNP
rs1045399044 346 dbSNP
rs1278434226 347 dbSNP
rs748620970 361 dbSNP
rs1205901010 367 dbSNP
rs535269284 374 dbSNP
rs949789721 379 dbSNP
rs912947764 385 dbSNP
rs1179378222 393 dbSNP
rs1382220624 394 dbSNP
rs1471152240 396 dbSNP
rs770567516 399 dbSNP
rs891095090 401 dbSNP
rs11190254 404 dbSNP
rs1029758302 407 dbSNP
rs1353638783 412 dbSNP
rs544383972 414 dbSNP
rs1284419600 417 dbSNP
rs549459347 418 dbSNP
rs997324000 422 dbSNP
rs530484825 426 dbSNP
rs899686266 431 dbSNP
rs1283943639 433 dbSNP
rs113350367 435 dbSNP
rs1231794744 438 dbSNP
rs1038210154 443 dbSNP
rs926122958 448 dbSNP
rs1346264759 449 dbSNP
rs1242973639 455 dbSNP
rs1328415518 456 dbSNP
rs1298901182 458 dbSNP
rs1399413868 459 dbSNP
rs1358587000 464 dbSNP
rs941295040 469 dbSNP
rs1317566623 472 dbSNP
rs765618742 472 dbSNP
rs964902736 472 dbSNP
rs1018906661 478 dbSNP
rs368877701 493 dbSNP
rs375534906 493 dbSNP
rs1178375089 501 dbSNP
rs887033287 503 dbSNP
rs182550670 505 dbSNP
rs1161236537 510 dbSNP
rs551033116 513 dbSNP
rs939049806 515 dbSNP
rs532879210 528 dbSNP
rs1384585850 535 dbSNP
rs577264951 536 dbSNP
rs1332216232 543 dbSNP
rs1407269711 544 dbSNP
rs1044850163 545 dbSNP
rs1373229175 553 dbSNP
rs1276760193 563 dbSNP
rs1340293338 572 dbSNP
rs947777473 578 dbSNP
rs1219557580 584 dbSNP
rs191560618 585 dbSNP
rs1354447862 591 dbSNP
rs1486994502 596 dbSNP
rs1270387680 597 dbSNP
rs1225421724 598 dbSNP
rs1490507472 599 dbSNP
rs1452689597 602 dbSNP
rs796939018 611 dbSNP
rs1201490854 615 dbSNP
rs1162177513 616 dbSNP
rs1260849244 616 dbSNP
rs1480769822 616 dbSNP
rs397940591 616 dbSNP
rs879104248 616 dbSNP
rs1390804091 617 dbSNP
rs1289690286 619 dbSNP
rs1296891486 622 dbSNP
rs1340390240 624 dbSNP
rs1226908288 626 dbSNP
rs1341746544 627 dbSNP
rs1298134912 628 dbSNP
rs1401013654 628 dbSNP
rs1279035386 631 dbSNP
rs1338968002 632 dbSNP
rs1244308220 635 dbSNP
rs1284915770 640 dbSNP
rs1361681161 648 dbSNP
rs994920269 652 dbSNP
rs1283818762 654 dbSNP
rs990284699 655 dbSNP
rs898348107 657 dbSNP
rs1338578256 662 dbSNP
rs957495620 669 dbSNP
rs924884270 681 dbSNP
rs1421744314 686 dbSNP
rs1285234939 687 dbSNP
rs1437185889 691 dbSNP
rs770184980 699 dbSNP
rs1349214428 703 dbSNP
rs746879138 704 dbSNP
rs1321355093 709 dbSNP
rs1001873759 711 dbSNP
rs955428994 717 dbSNP
rs1400615067 725 dbSNP
rs1030056771 736 dbSNP
rs1395736645 737 dbSNP
rs540803712 738 dbSNP
rs1476618562 753 dbSNP
rs1385192988 754 dbSNP
rs996982285 760 dbSNP
rs11190253 764 dbSNP
rs1352955658 779 dbSNP
rs1239657797 786 dbSNP
rs527637185 789 dbSNP
rs1262335330 802 dbSNP
rs1191257145 808 dbSNP
rs7073616 809 dbSNP
rs1199606408 819 dbSNP
rs1243397735 824 dbSNP
rs949739454 828 dbSNP
rs1176285581 832 dbSNP
rs772944700 835 dbSNP
rs1420266090 836 dbSNP
rs186268155 842 dbSNP
rs879807462 843 dbSNP
rs1376364290 845 dbSNP
rs886918446 851 dbSNP
rs1337748672 855 dbSNP
rs1259079526 867 dbSNP
rs1198293213 873 dbSNP
rs1444806166 884 dbSNP
rs543364106 885 dbSNP
rs1003858948 888 dbSNP
rs183112534 891 dbSNP
rs1310316844 892 dbSNP
rs1219825931 897 dbSNP
rs533269655 898 dbSNP
rs1045117957 899 dbSNP
rs748016439 901 dbSNP
rs947711103 908 dbSNP
rs914994825 931 dbSNP
rs1053444621 936 dbSNP
rs1325307964 938 dbSNP
rs936183204 940 dbSNP
rs924766757 942 dbSNP
rs557414294 955 dbSNP
rs190507435 959 dbSNP
rs1178375681 988 dbSNP
rs578133881 1001 dbSNP
rs1330422038 1005 dbSNP
rs1463788781 1011 dbSNP
rs1407774476 1035 dbSNP
rs912182941 1040 dbSNP
rs1170239086 1041 dbSNP
rs922663595 1042 dbSNP
rs975828980 1044 dbSNP
rs987672655 1046 dbSNP
rs950745940 1052 dbSNP
rs1413372201 1053 dbSNP
rs1291816695 1056 dbSNP
rs1365452525 1056 dbSNP
rs745984532 1061 dbSNP
rs1220898219 1065 dbSNP
rs781078683 1066 dbSNP
rs1404235846 1067 dbSNP
rs1026297638 1086 dbSNP
rs1266559076 1089 dbSNP
rs1238718591 1091 dbSNP
rs376504979 1093 dbSNP
rs777588996 1094 dbSNP
rs879273942 1096 dbSNP
rs758154482 1104 dbSNP
rs373426498 1105 dbSNP
rs1206052083 1106 dbSNP
rs764891474 1106 dbSNP
rs754528085 1111 dbSNP
rs368386864 1112 dbSNP
rs1200773961 1114 dbSNP
rs1294072515 1118 dbSNP
rs1452740270 1120 dbSNP
rs142892403 1122 dbSNP
rs1477052318 1123 dbSNP
rs2231687 1126 dbSNP
rs764593739 1127 dbSNP
rs1420531846 1139 dbSNP
rs760647511 1139 dbSNP
rs377239224 1149 dbSNP
rs1162827735 1152 dbSNP
rs1435005100 1156 dbSNP
rs186460666 1158 dbSNP
rs1349359181 1159 dbSNP
rs1268620585 1161 dbSNP
rs146008497 1166 dbSNP
rs1303694614 1167 dbSNP
rs770156735 1170 dbSNP
rs776825933 1175 dbSNP
rs770889501 1176 dbSNP
rs1329348691 1179 dbSNP
rs1269338829 1180 dbSNP
rs1282265040 1181 dbSNP
rs1230381847 1186 dbSNP
rs747005189 1191 dbSNP
rs149696723 1197 dbSNP
rs758281199 1198 dbSNP
rs747947854 1201 dbSNP
rs1322226826 1203 dbSNP
rs778611852 1209 dbSNP
rs375177450 1210 dbSNP
rs202111313 1212 dbSNP
rs372034566 1219 dbSNP
rs1003502153 1229 dbSNP
rs1243031921 1231 dbSNP
rs1276552467 1236 dbSNP
rs891485696 1239 dbSNP
rs906449340 1243 dbSNP
rs549605625 1252 dbSNP
rs904230733 1258 dbSNP
rs1165499636 1267 dbSNP
rs1012343886 1273 dbSNP
rs893444127 1278 dbSNP
rs1039189422 1280 dbSNP
rs537366039 1284 dbSNP
rs912046815 1286 dbSNP
rs987708429 1287 dbSNP
rs935061479 1288 dbSNP
rs1384587653 1296 dbSNP
rs556850599 1309 dbSNP
rs558512012 1313 dbSNP
rs919266489 1319 dbSNP
rs1356966493 1321 dbSNP
rs973397513 1324 dbSNP
rs760631047 1330 dbSNP
rs550945375 1335 dbSNP
rs532790726 1348 dbSNP
rs779762294 1349 dbSNP
rs755907089 1355 dbSNP
rs1223702047 1359 dbSNP
rs886046610 1361 dbSNP
rs750145039 1362 dbSNP
rs1208388768 1363 dbSNP
rs1237142262 1379 dbSNP
rs139851090 1382 dbSNP
rs1185545590 1403 dbSNP
rs1236413244 1404 dbSNP
rs1437819966 1409 dbSNP
rs1438178666 1415 dbSNP
rs547128653 1427 dbSNP
rs886046609 1431 dbSNP
rs942691713 1433 dbSNP
rs1402252054 1444 dbSNP
rs909871987 1451 dbSNP
rs1014192186 1455 dbSNP
rs1338199441 1457 dbSNP
rs955949055 1471 dbSNP
rs886046608 1474 dbSNP
rs1031755895 1476 dbSNP
rs1182703183 1487 dbSNP
rs781589361 1493 dbSNP
rs1262879858 1510 dbSNP
rs999901316 1510 dbSNP
rs1235864143 1519 dbSNP
rs1218812087 1525 dbSNP
rs529046851 1535 dbSNP
rs984229270 1536 dbSNP
rs1182552878 1546 dbSNP
rs1233414326 1560 dbSNP
rs904177546 1565 dbSNP
rs951441830 1568 dbSNP
rs757498127 1570 dbSNP
rs1189300619 1572 dbSNP
rs1428320420 1589 dbSNP
rs181768654 1590 dbSNP
rs190369277 1591 dbSNP
rs1397605252 1592 dbSNP
rs886046607 1594 dbSNP
rs1313116253 1596 dbSNP
rs576276908 1600 dbSNP
rs1338092422 1604 dbSNP
rs1376498303 1608 dbSNP
rs1283113989 1609 dbSNP
rs1346542200 1609 dbSNP
rs1012149988 1611 dbSNP
rs1225666084 1611 dbSNP
rs1290128507 1611 dbSNP
rs564407801 1612 dbSNP
rs1338933785 1619 dbSNP
rs1361768768 1626 dbSNP
rs1298071841 1644 dbSNP
rs1275177448 1646 dbSNP
rs1031964537 1654 dbSNP
rs999263210 1660 dbSNP
rs1268012348 1663 dbSNP
rs902280818 1665 dbSNP
rs1051485992 1668 dbSNP
rs919479972 1668 dbSNP
rs942076867 1672 dbSNP
rs1370628848 1679 dbSNP
rs1165913463 1686 dbSNP
rs934173786 1692 dbSNP
rs74981084 1693 dbSNP
rs1366676950 1699 dbSNP
rs1195976090 1703 dbSNP
rs1276661770 1706 dbSNP
rs1326121153 1710 dbSNP
rs1478163175 1711 dbSNP
rs186244558 1716 dbSNP
rs970772248 1726 dbSNP
rs1275418685 1740 dbSNP
rs917095645 1741 dbSNP
rs1290974965 1746 dbSNP
rs992621124 1758 dbSNP
rs546058308 1764 dbSNP
rs956062339 1769 dbSNP
rs1259376274 1773 dbSNP
rs145963002 1776 dbSNP
rs1489418524 1778 dbSNP
rs541168918 1786 dbSNP
rs574149332 1793 dbSNP
rs909924190 1796 dbSNP
rs763616218 1797 dbSNP
rs1427084410 1798 dbSNP
rs1296796514 1799 dbSNP
rs984114304 1803 dbSNP
rs753229745 1816 dbSNP
rs1319556031 1818 dbSNP
rs1279651795 1841 dbSNP
rs1245379637 1848 dbSNP
rs755134012 1850 dbSNP
rs754063121 1851 dbSNP
rs180797406 1852 dbSNP
rs555696632 1853 dbSNP
rs990733556 1858 dbSNP
rs756238457 1861 dbSNP
rs537685660 1868 dbSNP
rs957940064 1870 dbSNP
rs1205448735 1871 dbSNP
rs115287270 1876 dbSNP
rs1459673542 1879 dbSNP
rs1182497031 1886 dbSNP
rs993720053 1904 dbSNP
rs999151068 1905 dbSNP
rs902155191 1908 dbSNP
rs942259017 1913 dbSNP
rs905204275 1917 dbSNP
rs1160617451 1921 dbSNP
rs750869228 1923 dbSNP
rs1045052689 1931 dbSNP
rs1457687053 1933 dbSNP
rs1030509968 1952 dbSNP
rs997262715 1958 dbSNP
rs1385083663 1966 dbSNP
rs1444576233 1973 dbSNP
rs1173158903 1977 dbSNP
rs901361847 1980 dbSNP
rs1239549441 1981 dbSNP
rs577407869 1981 dbSNP
rs1321040835 1982 dbSNP
rs1202634100 1983 dbSNP
rs1263303382 1983 dbSNP
rs1462278212 1987 dbSNP
rs1174923407 1990 dbSNP
rs1250477665 1996 dbSNP
rs1423085742 2005 dbSNP
rs1420175036 2007 dbSNP
rs1007183374 2014 dbSNP
rs1427626001 2030 dbSNP
rs1469546207 2031 dbSNP
rs1177430984 2035 dbSNP
rs533958414 2042 dbSNP
rs1460552855 2045 dbSNP
rs886046606 2060 dbSNP
rs1372581343 2067 dbSNP
rs1391880544 2088 dbSNP
rs1802213 2090 dbSNP
rs1318773672 2104 dbSNP
rs978718543 2107 dbSNP
rs1343414429 2119 dbSNP
rs969013726 2146 dbSNP
rs1283551457 2149 dbSNP
rs1325195377 2151 dbSNP
rs55955456 2152 dbSNP
rs1201875824 2164 dbSNP
rs1250247008 2166 dbSNP
rs1487355609 2167 dbSNP
rs1198074727 2168 dbSNP
rs565343768 2169 dbSNP
rs1480324295 2181 dbSNP
rs929973697 2184 dbSNP
rs547424727 2187 dbSNP
rs557527426 2193 dbSNP
rs1426934871 2199 dbSNP
rs879397905 2199 dbSNP
rs529004838 2201 dbSNP
rs1355179865 2231 dbSNP
rs1030072316 2237 dbSNP
rs993641039 2242 dbSNP
rs898018133 2247 dbSNP
rs568214098 2248 dbSNP
rs1333361353 2262 dbSNP
rs1369347292 2267 dbSNP
rs114929589 2270 dbSNP
rs375951887 2274 dbSNP
rs1307576923 2275 dbSNP
rs1386680735 2281 dbSNP
rs762075313 2282 dbSNP
rs1490319552 2292 dbSNP
rs1333777849 2297 dbSNP
rs79573437 2301 dbSNP
rs1485052637 2315 dbSNP
rs1186149078 2318 dbSNP
rs949398841 2322 dbSNP
rs896475181 2332 dbSNP
rs1161706869 2338 dbSNP
rs1383351244 2340 dbSNP
rs1423903704 2350 dbSNP
rs1052554494 2352 dbSNP
rs138016109 2364 dbSNP
rs935388827 2367 dbSNP
rs1467615474 2373 dbSNP
rs1436692056 2376 dbSNP
rs924482935 2390 dbSNP
rs977952576 2393 dbSNP
rs1378158107 2395 dbSNP
rs966809462 2401 dbSNP
rs1029980570 2407 dbSNP
rs1175336324 2409 dbSNP
rs1431338889 2416 dbSNP
rs997714204 2418 dbSNP
rs964487033 2422 dbSNP
rs534710638 2437 dbSNP
rs1242946087 2439 dbSNP
rs1486954103 2447 dbSNP
rs1181877499 2453 dbSNP
rs886046605 2459 dbSNP
rs12416 2468 dbSNP
rs150810981 2471 dbSNP
rs189947699 2472 dbSNP
rs1399149255 2473 dbSNP
rs910508833 2474 dbSNP
rs888586359 2476 dbSNP
rs954408947 2484 dbSNP
rs1254869898 2487 dbSNP
rs886046604 2490 dbSNP
rs994411264 2496 dbSNP
rs1454039637 2497 dbSNP
rs897184787 2500 dbSNP
rs541480699 2502 dbSNP
rs1046383186 2504 dbSNP
rs1233239502 2506 dbSNP
rs1370592820 2508 dbSNP
rs1222810270 2518 dbSNP
rs1346331399 2520 dbSNP
rs1284546771 2529 dbSNP
rs1330875563 2530 dbSNP
rs1201539346 2545 dbSNP
rs949378075 2567 dbSNP
rs1461700285 2570 dbSNP
rs1185392913 2573 dbSNP
rs916670654 2576 dbSNP
rs1029937550 2578 dbSNP
rs1468691243 2580 dbSNP
rs1176778787 2581 dbSNP
rs1408995808 2583 dbSNP
rs781659102 2583 dbSNP
rs1055113150 2584 dbSNP
rs936524124 2587 dbSNP
rs769571551 2591 dbSNP
rs1470572029 2594 dbSNP
rs574033399 2595 dbSNP
rs1336753881 2598 dbSNP
rs925106997 2616 dbSNP
rs1376482448 2617 dbSNP
rs1352210800 2618 dbSNP
rs1440857626 2619 dbSNP
rs1327045732 2620 dbSNP
rs978003212 2623 dbSNP
rs966650785 2625 dbSNP
rs1016434087 2642 dbSNP
rs922965227 2648 dbSNP
rs1128642 2649 dbSNP
rs1324048328 2655 dbSNP
rs1023921785 2659 dbSNP
rs886046603 2668 dbSNP
rs184628753 2678 dbSNP
rs555416400 2679 dbSNP
rs896506229 2683 dbSNP
rs1052834649 2694 dbSNP
rs964707415 2699 dbSNP
rs886046602 2701 dbSNP
rs1464494606 2704 dbSNP
rs903898142 2706 dbSNP
rs1005960992 2720 dbSNP
rs1409963634 2726 dbSNP
rs1328931170 2728 dbSNP
rs1371919839 2730 dbSNP
rs952880831 2745 dbSNP
rs1302177863 2747 dbSNP
rs1159057561 2748 dbSNP
rs947256092 2750 dbSNP
rs1235153971 2751 dbSNP
rs1438796090 2751 dbSNP
rs796344574 2751 dbSNP
rs1268273535 2752 dbSNP
rs145731044 2756 dbSNP
rs1189233812 2761 dbSNP
rs1275409784 2764 dbSNP
rs1027150532 2774 dbSNP
rs1220473949 2785 dbSNP
rs757621603 2786 dbSNP
rs1452484358 2789 dbSNP
rs922954856 2793 dbSNP
rs1371759677 2802 dbSNP
rs1475359947 2806 dbSNP
rs972099498 2812 dbSNP
rs897411508 2819 dbSNP
rs1422233446 2826 dbSNP
rs1162464890 2831 dbSNP
rs1365808976 2837 dbSNP
rs1025606598 2839 dbSNP
rs1013608233 2846 dbSNP
rs1288736424 2847 dbSNP
rs895123603 2850 dbSNP
rs1431339071 2857 dbSNP
rs576268362 2857 dbSNP
rs984543332 2861 dbSNP
rs1413144053 2865 dbSNP
rs936741923 2875 dbSNP
rs557986782 2879 dbSNP
rs1042195456 2883 dbSNP
rs181585883 2889 dbSNP
rs923216829 2891 dbSNP
rs886046601 2898 dbSNP
rs565311174 2901 dbSNP
rs960914955 2905 dbSNP
rs976374968 2907 dbSNP
rs1446814653 2913 dbSNP
rs943078180 2913 dbSNP
rs1189715417 2917 dbSNP
rs1362399998 2918 dbSNP
rs1298782034 2927 dbSNP
rs1418986361 2930 dbSNP
rs1358458882 2934 dbSNP
rs1164762883 2936 dbSNP
rs1182434801 2941 dbSNP
rs910200635 2941 dbSNP
rs1368594282 2947 dbSNP
rs1031005098 2951 dbSNP
rs1156479822 2955 dbSNP
rs984578663 2959 dbSNP
rs999974154 2962 dbSNP
rs1322385144 2988 dbSNP
rs1380484789 2993 dbSNP
rs1451896936 2996 dbSNP
rs951765802 3006 dbSNP
rs1367467087 3009 dbSNP
rs553504659 3010 dbSNP
rs1184823321 3020 dbSNP
rs1026032338 3029 dbSNP
rs972927448 3034 dbSNP
rs535470105 3035 dbSNP
rs1478490348 3054 dbSNP
rs1247208699 3056 dbSNP
rs1263251249 3074 dbSNP
rs1350332699 3077 dbSNP
rs1218038403 3086 dbSNP
rs1025239684 3089 dbSNP
rs1014243832 3091 dbSNP
rs1282668809 3092 dbSNP
rs1270486970 3094 dbSNP
rs1460356266 3098 dbSNP
rs1183561622 3111 dbSNP
rs1256195081 3113 dbSNP
rs1425063886 3120 dbSNP
rs1179154775 3140 dbSNP
rs895177427 3143 dbSNP
rs1472752153 3156 dbSNP
rs1161087193 3159 dbSNP
rs1033638657 3174 dbSNP
rs1469199021 3185 dbSNP
rs888969272 3197 dbSNP
rs1402938406 3201 dbSNP
rs1397868991 3202 dbSNP
rs1050189393 3206 dbSNP
rs933240513 3224 dbSNP
rs923218858 3234 dbSNP
rs568042211 3244 dbSNP
rs74775778 3247 dbSNP
rs750160851 3248 dbSNP
rs1203537160 3251 dbSNP
rs903956314 3253 dbSNP
rs531527606 3254 dbSNP
rs1042828097 3256 dbSNP
rs570670083 3257 dbSNP
rs1399387649 3260 dbSNP
rs1193566204 3262 dbSNP
rs1343299088 3262 dbSNP
rs945240919 3272 dbSNP
rs901659716 3275 dbSNP
rs1483165110 3276 dbSNP
rs1183948555 3282 dbSNP
rs1426888957 3297 dbSNP
rs984557435 3307 dbSNP
rs1176626074 3329 dbSNP
rs188763411 3337 dbSNP
rs375153079 3345 dbSNP
rs1296504635 3362 dbSNP
rs184330466 3365 dbSNP
rs1410627398 3383 dbSNP
rs540618488 3389 dbSNP
rs1162414162 3395 dbSNP
rs984461109 3399 dbSNP
rs10883407 3417 dbSNP
rs192674807 3421 dbSNP
rs1477783320 3426 dbSNP
rs1314444523 3427 dbSNP
rs919027006 3429 dbSNP
rs972196065 3436 dbSNP
rs1250234560 3439 dbSNP
rs188726020 3445 dbSNP
rs960863957 3448 dbSNP
rs1240821774 3453 dbSNP
rs1266344421 3458 dbSNP
rs1201489831 3459 dbSNP
rs1490105057 3465 dbSNP
rs1031705019 3476 dbSNP
rs1452594851 3477 dbSNP
rs1269265540 3478 dbSNP
rs11405417 3486 dbSNP
rs1430502048 3486 dbSNP
rs1289573440 3487 dbSNP
rs968479225 3488 dbSNP
rs34131206 3512 dbSNP
rs1363938860 3518 dbSNP
rs961598180 3521 dbSNP
rs1294465386 3522 dbSNP
rs1025547673 3525 dbSNP
rs992465077 3528 dbSNP
rs959607481 3538 dbSNP
rs1033859543 3540 dbSNP
rs997337758 3544 dbSNP
rs1229975315 3547 dbSNP
rs184592729 3557 dbSNP
rs1289037918 3562 dbSNP
rs752667154 3566 dbSNP
rs1221906197 3568 dbSNP
rs1266949545 3586 dbSNP
rs1484785704 3593 dbSNP
rs1185802510 3603 dbSNP
rs1000825478 3607 dbSNP
rs1451326305 3611 dbSNP
rs765785143 3619 dbSNP
rs1359824677 3631 dbSNP
rs1383520150 3636 dbSNP
rs772993193 3636 dbSNP
rs1276495612 3651 dbSNP
rs562028646 3669 dbSNP
rs886046600 3670 dbSNP
rs543904506 3672 dbSNP
rs1010047850 3699 dbSNP
rs1323642965 3704 dbSNP
rs576180531 3708 dbSNP
rs1366548548 3716 dbSNP
rs1437969188 3717 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903830
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / CTLTD_shCTL_b
Location of target site NM_004376 | 3UTR | CUUCACCUUCUGCCAUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903831
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / 124TD_shELAVL3_a
Location of target site NM_004376 | 3UTR | UUCACCUUCUGCCAUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000016171.5 | 3UTR | AUGUGACACACUGGCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
Click to see details
133 hsa-miR-3179 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102087 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT110061 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112198 BTG2 BTG anti-proliferation factor 2 2 2
MIRT117668 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT146657 MINK1 misshapen like kinase 1 2 2
MIRT175505 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT180535 TXNIP thioredoxin interacting protein 2 2
MIRT190624 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT190650 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT366902 NONO non-POU domain containing octamer binding 2 2
MIRT443554 ZFP3 ZFP3 zinc finger protein 2 2
MIRT445953 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT446042 HMCN1 hemicentin 1 2 2
MIRT447968 MSH6 mutS homolog 6 2 2
MIRT448634 ONECUT1 one cut homeobox 1 2 2
MIRT449316 MRO maestro 2 2
MIRT451380 C19orf43 telomerase RNA component interacting RNase 2 2
MIRT451547 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451807 CDCA3 cell division cycle associated 3 2 4
MIRT451916 ILK integrin linked kinase 2 2
MIRT451938 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452189 KIAA1456 KIAA1456 2 2
MIRT452498 HMGXB3 HMG-box containing 3 2 2
MIRT452548 ZNF467 zinc finger protein 467 2 2
MIRT453844 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454515 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455363 KDM5C lysine demethylase 5C 2 2
MIRT455455 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455628 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 10
MIRT455639 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 10
MIRT455690 GLO1 glyoxalase I 2 2
MIRT456300 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT456784 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT456819 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457566 ZNF34 zinc finger protein 34 2 2
MIRT457604 IDS iduronate 2-sulfatase 2 2
MIRT458236 NXPH3 neurexophilin 3 2 2
MIRT458313 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458350 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458670 GPR35 G protein-coupled receptor 35 2 2
MIRT459675 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT461126 RAB36 RAB36, member RAS oncogene family 2 2
MIRT461918 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462301 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463520 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464378 URM1 ubiquitin related modifier 1 2 2
MIRT464614 UBE4B ubiquitination factor E4B 2 2
MIRT464711 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465520 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465974 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466058 TMEM189 transmembrane protein 189 2 2
MIRT466548 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT466647 TAGLN2 transgelin 2 2 2
MIRT467357 SP2 Sp2 transcription factor 2 2
MIRT468744 SDC2 syndecan 2 2 2
MIRT470244 PRRC2A proline rich coiled-coil 2A 2 2
MIRT471426 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT471732 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472190 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472450 NAV2 neuron navigator 2 2 6
MIRT474563 KLHDC3 kelch domain containing 3 2 2
MIRT474936 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475165 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475399 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT475426 ICK intestinal cell kinase 2 2
MIRT477090 FAM168A family with sequence similarity 168 member A 2 2
MIRT478458 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478953 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480096 CALR calreticulin 2 2
MIRT481924 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT483217 APOA1 apolipoprotein A1 2 6
MIRT483882 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483923 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483942 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484209 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484512 SYT7 synaptotagmin 7 2 2
MIRT484709 RNF11 ring finger protein 11 2 2
MIRT485356 MYO1C myosin IC 2 4
MIRT485615 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT486584 ZNF619 zinc finger protein 619 2 2
MIRT487013 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487621 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487801 GPR20 G protein-coupled receptor 20 2 4
MIRT488134 GPR107 G protein-coupled receptor 107 2 2
MIRT488773 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488854 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489783 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490102 FN3K fructosamine 3 kinase 2 2
MIRT490389 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT490434 MYL9 myosin light chain 9 2 2
MIRT490451 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490880 OSBP oxysterol binding protein 2 2
MIRT491037 ALPK3 alpha kinase 3 2 2
MIRT491250 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491748 SEMA3F semaphorin 3F 2 2
MIRT492235 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492490 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492505 RANBP10 RAN binding protein 10 2 4
MIRT492773 PDGFB platelet derived growth factor subunit B 2 2
MIRT492922 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT493459 ITFG3 family with sequence similarity 234 member A 2 2
MIRT493654 HDLBP high density lipoprotein binding protein 2 2
MIRT494011 DUSP9 dual specificity phosphatase 9 2 2
MIRT499412 PLCG2 phospholipase C gamma 2 2 4
MIRT499552 C15orf43 telomere repeat binding bouquet formation protein 2 2 2
MIRT501836 NCOA2 nuclear receptor coactivator 2 2 2
MIRT501950 MAT2A methionine adenosyltransferase 2A 2 10
MIRT504066 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT504509 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT508466 HOXB6 homeobox B6 2 4
MIRT512373 CPM carboxypeptidase M 2 2
MIRT513578 EVX1 even-skipped homeobox 1 2 2
MIRT517763 ZNF366 zinc finger protein 366 2 4
MIRT519773 ZNF354B zinc finger protein 354B 2 8
MIRT523568 GGCX gamma-glutamyl carboxylase 2 4
MIRT532802 CLDN11 claudin 11 2 2
MIRT544299 TSPYL1 TSPY like 1 2 2
MIRT544862 MYH2 myosin heavy chain 2 2 4
MIRT556731 KLHL15 kelch like family member 15 2 4
MIRT564347 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568924 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT569012 CXorf36 chromosome X open reading frame 36 2 2
MIRT569256 FAM129B family with sequence similarity 129 member B 2 2
MIRT569591 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT569779 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT570034 FAM228A family with sequence similarity 228 member A 2 2
MIRT573803 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574190 ZNF264 zinc finger protein 264 2 2
MIRT576153 Hmox1 heme oxygenase 1 2 2
MIRT611311 CA8 carbonic anhydrase 8 2 4
MIRT673429 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT674976 SH3BP2 SH3 domain binding protein 2 2 2
MIRT692712 MEAF6 MYST/Esa1 associated factor 6 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-3179 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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