miRTarBase - #MIRT479534


—
pre-miRNA Information
pre-miRNA hsa-mir-4640   
Genomic Coordinates chr6: 30890883 - 30890972
Description Homo sapiens miR-4640 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4640-5p
Sequence 9| UGGGCCAGGGAGCAGCUGGUGGG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1392105945 7 dbSNP
rs939712790 9 dbSNP
rs762825841 15 dbSNP
rs71552023 20 dbSNP
rs1305909531 21 dbSNP
rs750017220 21 dbSNP
rs1375436057 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B32FZJ miR-4640 Safety Biomarker (SAF) Clinical/Experimental Data Expression lower Urine Quantitative polymerase chain reaction
Gene Information
Gene Symbol CDC5L   
Synonyms CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1
Description cell division cycle 5 like
Transcript NM_001253   
Expression
Putative miRNA Targets on CDC5L
3'UTR of CDC5L
(miRNA target sites are highlighted)		 
>CDC5L|NM_001253|3'UTR
   1 AGTACAGTTTATATTCTGTCACAGGATTAATTAATTGCCGGTTTTCATACTCTAGAAGGCTGAAACTGATGTTTATCTTC
  81 ATTGACAAATTTACCCACCATCTGTGGTTTTTCAGTTGTTTATTTTAAATGATATCGATCTTACACATTCTGTGTATAAA
 161 GACCTTAACTCCACAGGACGGACATTTTAGAGTTTAAATTATTAAGGCTATCATTCTTTTAGTAATGTCATATTTGCAAA
 241 CTTTTTTAGTTTTGGCCTTTAATTTAAAAAGCCTAATTTTAAAGTGCTGCCTGTGAGTAACTCTTGAATAAAAACAAAAT
 321 ATAAAAAATTGAGAATGTAGCCTTTTGTTTGAAGTAATTAGATACTTAAGAGTGCCTGCAAACCAGCAGCTATGTACTCT
 401 GTGTCATATTTAATGAGTAACTCTTGGGTAATCAAAATGGTGATGCAGTATCTTAAACACTTAAGAGGCAGTTCTTTGTG
 481 GCTTTGTTAGTTTCAGCAAAGAGTGGTCATTTCTGTATACACTGACAAGTTAGATTAACTTTTTAGTACCTCAAATTTTT
 561 TTTTTGTTAATATCACTTTAAAGAAGGTCTCTTGTCTGCCAGCTACTTAAATAATTTATGGGTCAGGGCTTAAAAGATTT
 641 AACTTCCTTGCCCCATTATTTTCTTATAAGTATTTTTTGACAAAGGCATTTTAAAAGTTAATTTCAAGAAGGCCATCAAA
 721 CTTAAAGCTCTATGTTTAGCCTAAGAAGTCAGTTACATCAGTGTAGAATTTGGGGAATGGATAGAGGTGGAGATATTTAA
 801 TTTTATATAATTCATATAAATTGATTTAGTTACAGTATCAGTTGGCTACAAGCTCATTATAGACTAGCAATGTTTTGACA
 881 TCACCAAAAACGTTTGCCCAGTCTTAGAATACTAGGGACTATAGGAAGGGAAGGGATTCATTCATTCATTCGATATTGAA
 961 TGTATACCCTGTGCCAGAGTCTTAGAGAGAGAACAACAAACAAAATAGGCCTAGTTCTTGTTTAGTAGAGCTTATAGTCT
1041 TTTGAGAATGACAGACAATTAAAATCCAAATGTTTATTTGGTGATTCTTATGTGTCAGACACTTAAGTGTTGGGAGATAA
1121 GCAGTTATTAAGACAGAGTTCTTGCTCTCATGGAGGTGACATTAGTGGGGAGGAGATACTAAGTATGTCCAGGGAAAGTA
1201 TCAGACCATGAGTTTTAGATTCTGTGGAGGAAATTAAAGTAGGGTGATTATGAGATAGTGAATGAGTGGCTATTTTAGAC
1281 TGGACGATCAAAGAGACCTCTTGGAAGGCAGCTATGCTCACCACTATACCACTGCACTGTGCCGCACCGTACCACTATAA
1361 GCTGCACGGCCAAAGAGACCTCTTAAAGAAGTAACATTTAAGATAACATGTGATTGACATTTTAGAATGGGCTATCCTTG
1441 TGAGATTCAAGGAAAGAACATCCTAGGTGGAGTGAATAGCAAACATAAAGCCTCTTTTGTATGTTTGAGGAACAAAAAGG
1521 ACAATGCAGCTAGAGTGTCAAGAATGGCATTTCTGTATATAAGACCTCGTTGTATAGAGCCACATAAATAAGGCTATAAT
1601 AAGGAATTTGGATCTTACTTTAAATATGATAAGAATCGATGAGAAGATCTAAGCAAAGGAATGACATGATCAGATTTGGT
1681 TTTAGAAACATCACTATCTCCTTAGTGTGTAAAATCTCACCAGGCTGGAGATAGGGAAGCCAGTCCAATTAGGAGCCTGA
1761 TGCAGTGATCCAGACAAAAAAATAATAGTGATTCTAACTAGAGTCCAGGTAATAGTAGTGGAGATATGTGGAGAGACATG
1841 ATAGGTATATACTTAATAGTCTTATCAGACGATAAATTGATATTTTCCTGGTGTGTAGTCACTTAATTCAAATACTTTTT
1921 TCAGTAAGTTCTGGGTTTTCTAGGAAAAACTTCAGTATCATCAGTGAATAATGATAGTGTTTCTTCTGATAGTTTTATTT
2001 CACTTTTATTGCATGTTTTGTTATCTGAAATGTTTAGGACAATGTTAACAATAATGATGTTAGACATTTTTTTTTCTTAT
2081 TTTAATGGGAATGTCCATAGTTTTAAGTTTGCTGTTGGGAGTTAGATAGTCTTTATCTGAAAGACAGTGTCTCTCTTTTA
2161 GTTTTTAAAGAGTTTGAATTAGAAATGGCTCTGGAACTTTAAACAGTATACCATTTGGGCATCTATTAAAGCATTCATAT
2241 AATTGTTCTCATTTGATGTTTTGATGAGGTATATTAATAGATTTTCCCACATTAAATCATCTTTGCACTCCTGGAATCAG
2321 GTAGATTAATTTTTAAAAGAAATTTTAAAGGATTTATAGTTTATTTGCACTTTTTGTAGACTTGAATTATATGGATTTAA
2401 AAGTTGATCTAATATTAATAAAGGCTCACTTTGTTTTCAAAATTTGAAGTAATTCACATACTTATAGCCTAAAAAAATCG
2481 GCAGGAATTACAAAATTTCAAAACTGGCACATTGTAAACTGCATATGCATTTGCCAGGTAGTGGTGCCACTTGAAATGGT
2561 GAACAGACACACTGTTATCCTTTGTCAGTATCCTGTAAAGCCCAGGATTCTTTACCAGCACCATACAGCGATTTTGGTGA
2641 CTATTTTAACATTCACACTGAGGCCAGGGGTGGTGAGTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGAGG
2721 ATCATTTGAGCTCAGGAGTTCAAGATTAGCCTGGGTAACATAGTGAGACCCTGTCTCTATTAAAAAATAATAATAAAAAT
2801 AACATTCACATTGGTATTGTTCACTAAGGTATTGGTTGTTAAGGCATTCATTAAGGTATTGTTAAAACTTGTGTTAAGCA
2881 TGTTAAAGTCTCAGTAACTTTGGGATAGAAATAAAATGTGATAAAAAGCTGAAAGAAACCACCACAAGGGAGAGTCCTTT
2961 TTGAAATATTAGAGACATAATGCTGTCTAATAAAAAACGACATCAAAGAAAAACTACACTACAGTGACTGCAGACTTAAT
3041 GTTGGCCAACCATGCATCCTCCCTAGAAATGCATTTGAATTTGATTTACTAATCTTTTATTTAGGAAATTTACATTTTTA
3121 CATTAGTGAGATTGGTCTTTTGGGCTATTGTACTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTCTCACCCAGGC
3201 TGGAGTGCAGTAGTGCAATCTTGGCCCACTGCAACCTCTGCCTCCTGGGCTCGAGTGATTCTCTGCCTCAGCCTTCCAAG
3281 TAGCTGGGACTACAGGCATGTGCCACCGCACCTGGCTAATTTTTGTGTTTTTAGTAGAGATGGGGTTTTGCTATGTTGGC
3361 CAGGCTGGTCTTGAATTCCTGACCTCAGGTGATCCACCTACCTCGGCCTCCCAAAGTGCTAGAATTACAGGTGTGAGCCA
3441 CCATGCCCAGCCTGGTTATTGTATTTTGATATTGGGATTTTGCTAGCTCTCTAAAGTAAATAGGATAACTGTATATCTTT
3521 TTCTGTGCATTAAGCAGTTATAACATGGGAATGATTTGTTCATGAAAGGTTGAAAGTCTGTACTTACAGAACTTTTGAGT
3601 TCACAGTGCTTTCTGGAAATAATTTCTTTATAACTGTCAGTTTCTTTTGTGACTATTATGTTACCTATTTTTAAATTTAA
3681 GCAACTTTAAATTAAAAAAATTGTTTTTAAAAT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggGUGGUCGACG-AGGGACCGGGu 5'
            || :|| |||  :|:|||||| 
Target 5' tgCAGTAG-TGCAATCTTGGCCCa 3'
 3206 - 3228 144.00 -24.20
2 
miRNA  3' ggguggucgacGAGGGACCGGGu 5'
                     ||:||| |||| 
Target 5' aaaagatttaaCTTCCTTGCCCc 3'
 632 - 654 124.00 -15.30
3 
miRNA  3' ggGUGGUCGACGAGGGACCGGGu 5'
            || |  |||| :||||| |: 
Target 5' tgCAACCTCTGCCTCCTGGGCTc 3'
 3230 - 3252 121.00 -22.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN24301886 6 COSMIC
COSN30500446 17 COSMIC
COSN30518684 21 COSMIC
COSN21601727 40 COSMIC
COSN31502359 47 COSMIC
COSN26587048 60 COSMIC
COSN30160669 73 COSMIC
COSN31490176 151 COSMIC
COSN20075573 159 COSMIC
COSN31582878 169 COSMIC
COSN31962630 181 COSMIC
COSN30540588 256 COSMIC
COSN30112917 260 COSMIC
COSN9783994 261 COSMIC
COSN31570203 271 COSMIC
COSN32065352 291 COSMIC
COSN31488227 301 COSMIC
COSN17520106 320 COSMIC
COSN22647593 552 COSMIC
COSN7883726 558 COSMIC
COSN6321353 692 COSMIC
COSN1333568 1330 COSMIC
COSN17207307 1603 COSMIC
COSN22529526 1826 COSMIC
COSN5630531 1851 COSMIC
COSN23845691 1931 COSMIC
COSN6321354 2080 COSMIC
COSN29465629 2129 COSMIC
COSN2162847 2320 COSMIC
COSN7883727 2384 COSMIC
COSN24714107 2697 COSMIC
COSN17740051 2999 COSMIC
COSN21736763 3021 COSMIC
COSN5630532 3107 COSMIC
COSN26022998 3179 COSMIC
COSN5630533 3263 COSMIC
COSN9783995 3282 COSMIC
COSN21095692 3469 COSMIC
COSN23688272 3603 COSMIC
rs11572061 1630 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs536182131 3 dbSNP
rs1438344931 6 dbSNP
rs76403747 7 dbSNP
rs11572055 12 dbSNP
rs1472208718 19 dbSNP
rs1188209564 20 dbSNP
rs1419664179 23 dbSNP
rs762837144 25 dbSNP
rs1434626188 26 dbSNP
rs1169004439 35 dbSNP
rs1396347831 37 dbSNP
rs369948548 40 dbSNP
rs774356348 41 dbSNP
rs763717273 42 dbSNP
rs759469566 47 dbSNP
rs62401212 48 dbSNP
rs1407565032 49 dbSNP
rs752833648 51 dbSNP
rs998886509 54 dbSNP
rs1484280393 58 dbSNP
rs1238122727 70 dbSNP
rs756934782 73 dbSNP
rs1028202422 75 dbSNP
rs534025095 96 dbSNP
rs189604170 100 dbSNP
rs986110941 101 dbSNP
rs1316055972 108 dbSNP
rs1304416704 123 dbSNP
rs1229668132 134 dbSNP
rs180938090 137 dbSNP
rs947359337 138 dbSNP
rs1023088841 145 dbSNP
rs544607473 148 dbSNP
rs1374206824 157 dbSNP
rs1300537129 158 dbSNP
rs1454648340 160 dbSNP
rs1433100270 166 dbSNP
rs551748769 180 dbSNP
rs778192588 181 dbSNP
rs113972330 183 dbSNP
rs546555861 193 dbSNP
rs1414689016 202 dbSNP
rs1187349726 207 dbSNP
rs866086806 208 dbSNP
rs894748263 209 dbSNP
rs1217163078 211 dbSNP
rs1485457925 213 dbSNP
rs960620352 228 dbSNP
rs1223376499 231 dbSNP
rs1390567663 232 dbSNP
rs186405901 233 dbSNP
rs1292250705 238 dbSNP
rs1049108130 244 dbSNP
rs888142332 249 dbSNP
rs575063900 256 dbSNP
rs1341775858 257 dbSNP
rs1240319955 258 dbSNP
rs749816271 271 dbSNP
rs750237646 274 dbSNP
rs1004282459 276 dbSNP
rs1345040152 277 dbSNP
rs1015377518 285 dbSNP
rs542202383 305 dbSNP
rs985144144 318 dbSNP
rs560668051 324 dbSNP
rs1028087714 329 dbSNP
rs771242893 336 dbSNP
rs953974834 337 dbSNP
rs1425864088 341 dbSNP
rs1193878226 342 dbSNP
rs143762164 352 dbSNP
rs1040459299 357 dbSNP
rs1195566300 361 dbSNP
rs989438525 362 dbSNP
rs1249111594 363 dbSNP
rs367779236 367 dbSNP
rs934623285 383 dbSNP
rs1022633325 385 dbSNP
rs1272171408 386 dbSNP
rs968784296 387 dbSNP
rs977793013 393 dbSNP
rs1053130061 400 dbSNP
rs1258128971 400 dbSNP
rs893168286 401 dbSNP
rs370589316 414 dbSNP
rs564988369 421 dbSNP
rs1293997195 427 dbSNP
rs938726499 434 dbSNP
rs373877225 449 dbSNP
rs1388899105 451 dbSNP
rs531985972 462 dbSNP
rs1044658835 472 dbSNP
rs906015673 479 dbSNP
rs1003007676 495 dbSNP
rs1378394815 496 dbSNP
rs1168536046 502 dbSNP
rs916110305 503 dbSNP
rs1034695223 504 dbSNP
rs1371293651 518 dbSNP
rs960487628 519 dbSNP
rs948847040 531 dbSNP
rs1048678957 533 dbSNP
rs1461343942 550 dbSNP
rs1454555505 555 dbSNP
rs1191423760 556 dbSNP
rs1252144352 556 dbSNP
rs199649069 556 dbSNP
rs201289983 557 dbSNP
rs1165932684 567 dbSNP
rs1402114449 570 dbSNP
rs1447436567 571 dbSNP
rs1325083116 573 dbSNP
rs993692797 574 dbSNP
rs1336811192 578 dbSNP
rs1387975306 584 dbSNP
rs888687211 594 dbSNP
rs1250133412 595 dbSNP
rs939710104 598 dbSNP
rs1236063064 603 dbSNP
rs190117786 606 dbSNP
rs1306548695 632 dbSNP
rs1439030483 633 dbSNP
rs1227245982 637 dbSNP
rs1329736019 641 dbSNP
rs1390908768 647 dbSNP
rs1394347121 650 dbSNP
rs900947251 651 dbSNP
rs11572056 654 dbSNP
rs984687856 659 dbSNP
rs1171490520 662 dbSNP
rs1441274960 664 dbSNP
rs1028014023 666 dbSNP
rs759942368 667 dbSNP
rs1467230033 668 dbSNP
rs1192973483 673 dbSNP
rs889657697 673 dbSNP
rs1268398085 681 dbSNP
rs868510933 685 dbSNP
rs181400818 687 dbSNP
rs1022221552 698 dbSNP
rs1191223586 699 dbSNP
rs754871558 706 dbSNP
rs923311192 713 dbSNP
rs1334117849 716 dbSNP
rs966991043 719 dbSNP
rs1314914045 733 dbSNP
rs998886413 735 dbSNP
rs1374809892 740 dbSNP
rs777913876 753 dbSNP
rs548124232 757 dbSNP
rs960015828 760 dbSNP
rs1465909100 762 dbSNP
rs566282730 776 dbSNP
rs1164175525 778 dbSNP
rs547998772 781 dbSNP
rs186028119 782 dbSNP
rs1369734025 787 dbSNP
rs1293602251 788 dbSNP
rs558590346 797 dbSNP
rs1380183894 803 dbSNP
rs947391628 808 dbSNP
rs1257453527 824 dbSNP
rs776679428 827 dbSNP
rs1449166849 838 dbSNP
rs1285383696 841 dbSNP
rs1204825583 846 dbSNP
rs984660584 849 dbSNP
rs906130560 850 dbSNP
rs1286137562 851 dbSNP
rs1234004005 868 dbSNP
rs1354824220 873 dbSNP
rs1342814557 881 dbSNP
rs570631145 887 dbSNP
rs746054981 888 dbSNP
rs1317329540 892 dbSNP
rs940241240 893 dbSNP
rs1002955264 897 dbSNP
rs1392455049 898 dbSNP
rs537981555 903 dbSNP
rs1320436865 910 dbSNP
rs1460472579 916 dbSNP
rs1224334144 920 dbSNP
rs1057226845 923 dbSNP
rs1266119230 936 dbSNP
rs1485554485 942 dbSNP
rs1243095858 948 dbSNP
rs1036711242 952 dbSNP
rs922299357 954 dbSNP
rs148942306 955 dbSNP
rs1265569842 956 dbSNP
rs933658576 957 dbSNP
rs1478052780 962 dbSNP
rs1334335142 966 dbSNP
rs1049503510 972 dbSNP
rs1216293478 976 dbSNP
rs1340022704 982 dbSNP
rs1269471184 984 dbSNP
rs372649780 984 dbSNP
rs532790702 984 dbSNP
rs558893449 984 dbSNP
rs753377080 984 dbSNP
rs80033344 992 dbSNP
rs1439695884 995 dbSNP
rs542465565 995 dbSNP
rs1391716948 1005 dbSNP
rs1172154705 1007 dbSNP
rs1410000069 1010 dbSNP
rs1425493466 1018 dbSNP
rs554518068 1019 dbSNP
rs770328705 1024 dbSNP
rs964627176 1024 dbSNP
rs1165324431 1026 dbSNP
rs1344114337 1033 dbSNP
rs1450950959 1035 dbSNP
rs1194557389 1036 dbSNP
rs1468179272 1050 dbSNP
rs1299702413 1051 dbSNP
rs572642914 1059 dbSNP
rs1401055490 1068 dbSNP
rs1293064224 1071 dbSNP
rs754636744 1073 dbSNP
rs775984030 1077 dbSNP
rs923123770 1080 dbSNP
rs536313906 1088 dbSNP
rs956097259 1091 dbSNP
rs902441540 1092 dbSNP
rs775010295 1097 dbSNP
rs1442319258 1110 dbSNP
rs1353408323 1117 dbSNP
rs546441966 1118 dbSNP
rs1328845750 1143 dbSNP
rs999878822 1145 dbSNP
rs1397315966 1147 dbSNP
rs1174685192 1166 dbSNP
rs1314009156 1168 dbSNP
rs1454068501 1169 dbSNP
rs1393510881 1171 dbSNP
rs1179098796 1180 dbSNP
rs34493843 1192 dbSNP
rs1481040466 1193 dbSNP
rs914653496 1204 dbSNP
rs372643728 1209 dbSNP
rs1202414337 1211 dbSNP
rs1044375006 1224 dbSNP
rs1288494886 1235 dbSNP
rs556258823 1237 dbSNP
rs960067760 1238 dbSNP
rs1345403566 1245 dbSNP
rs1014255921 1248 dbSNP
rs1210357744 1249 dbSNP
rs142870354 1250 dbSNP
rs564699240 1251 dbSNP
rs1277230783 1254 dbSNP
rs11572057 1256 dbSNP
rs1377822306 1262 dbSNP
rs930154284 1273 dbSNP
rs35957712 1282 dbSNP
rs1313957934 1283 dbSNP
rs984322059 1286 dbSNP
rs1163196230 1287 dbSNP
rs1374019130 1293 dbSNP
rs1161631355 1295 dbSNP
rs763620230 1296 dbSNP
rs887532389 1299 dbSNP
rs1005852473 1302 dbSNP
rs910010220 1315 dbSNP
rs544015236 1316 dbSNP
rs1258158565 1324 dbSNP
rs1187059222 1327 dbSNP
rs764437370 1333 dbSNP
rs773920513 1335 dbSNP
rs11572058 1338 dbSNP
rs922851978 1344 dbSNP
rs557674653 1345 dbSNP
rs750128935 1348 dbSNP
rs955867999 1349 dbSNP
rs1049346506 1350 dbSNP
rs190873715 1353 dbSNP
rs946430618 1355 dbSNP
rs11572059 1356 dbSNP
rs1290968473 1358 dbSNP
rs879388479 1362 dbSNP
rs1454595445 1367 dbSNP
rs766232944 1368 dbSNP
rs1238146208 1369 dbSNP
rs999363732 1374 dbSNP
rs1418662885 1381 dbSNP
rs1187192258 1389 dbSNP
rs1311563568 1393 dbSNP
rs1263709251 1401 dbSNP
rs200730186 1406 dbSNP
rs11572060 1408 dbSNP
rs1186907654 1408 dbSNP
rs1056428878 1409 dbSNP
rs202023110 1410 dbSNP
rs1215170787 1413 dbSNP
rs938707567 1415 dbSNP
rs527453586 1420 dbSNP
rs753566741 1435 dbSNP
rs1233255180 1436 dbSNP
rs1014265697 1441 dbSNP
rs1313782030 1447 dbSNP
rs1210539253 1453 dbSNP
rs1318867636 1453 dbSNP
rs1443348124 1462 dbSNP
rs1395361291 1468 dbSNP
rs930126813 1475 dbSNP
rs1049042631 1488 dbSNP
rs1232293227 1495 dbSNP
rs1374736945 1520 dbSNP
rs1441419304 1524 dbSNP
rs1277228231 1526 dbSNP
rs1425156621 1527 dbSNP
rs1022947169 1529 dbSNP
rs551929200 1530 dbSNP
rs754957602 1534 dbSNP
rs1251946839 1536 dbSNP
rs1456386516 1538 dbSNP
rs1180365066 1543 dbSNP
rs1211305229 1547 dbSNP
rs1481297203 1548 dbSNP
rs1253604554 1556 dbSNP
rs1006076221 1569 dbSNP
rs771809080 1569 dbSNP
rs1016999744 1570 dbSNP
rs961881260 1574 dbSNP
rs1038832732 1586 dbSNP
rs1372023242 1589 dbSNP
rs1325401007 1590 dbSNP
rs972843847 1597 dbSNP
rs1171403742 1600 dbSNP
rs1029873479 1601 dbSNP
rs1298735832 1614 dbSNP
rs1426803282 1617 dbSNP
rs1416574126 1626 dbSNP
rs1461399846 1627 dbSNP
rs11572061 1630 dbSNP
rs1354243294 1638 dbSNP
rs1454514444 1638 dbSNP
rs778667399 1639 dbSNP
rs74968852 1640 dbSNP
rs751693420 1641 dbSNP
rs574212518 1647 dbSNP
rs556387203 1652 dbSNP
rs946385455 1657 dbSNP
rs1250602408 1659 dbSNP
rs1196924686 1662 dbSNP
rs997204416 1666 dbSNP
rs1445233779 1668 dbSNP
rs979631789 1669 dbSNP
rs138178787 1672 dbSNP
rs891707420 1679 dbSNP
rs1377785421 1685 dbSNP
rs1440225038 1688 dbSNP
rs1231318828 1693 dbSNP
rs994918722 1697 dbSNP
rs1337659440 1700 dbSNP
rs1307758537 1704 dbSNP
rs1390854167 1706 dbSNP
rs1368653768 1714 dbSNP
rs1314586631 1716 dbSNP
rs1435112288 1720 dbSNP
rs923705032 1727 dbSNP
rs1273350649 1730 dbSNP
rs1010191378 1732 dbSNP
rs1455005431 1734 dbSNP
rs1021867452 1742 dbSNP
rs968550423 1743 dbSNP
rs1471289042 1753 dbSNP
rs142184450 1756 dbSNP
rs1056269932 1760 dbSNP
rs1034414329 1767 dbSNP
rs368611454 1769 dbSNP
rs1465766521 1773 dbSNP
rs1278331323 1775 dbSNP
rs1198987023 1776 dbSNP
rs1353149740 1778 dbSNP
rs960001550 1779 dbSNP
rs1238437311 1783 dbSNP
rs572756259 1785 dbSNP
rs947921658 1786 dbSNP
rs540028927 1788 dbSNP
rs993245689 1805 dbSNP
rs1354639941 1813 dbSNP
rs1415313240 1813 dbSNP
rs1044988152 1817 dbSNP
rs905880322 1820 dbSNP
rs1385233680 1826 dbSNP
rs1196114484 1828 dbSNP
rs553965299 1834 dbSNP
rs145913389 1843 dbSNP
rs1248162064 1853 dbSNP
rs1419372900 1854 dbSNP
rs1478154075 1856 dbSNP
rs372376056 1856 dbSNP
rs1017444985 1871 dbSNP
rs1185517289 1872 dbSNP
rs1449042596 1879 dbSNP
rs1262703172 1881 dbSNP
rs1208344669 1883 dbSNP
rs757322859 1892 dbSNP
rs1275104484 1903 dbSNP
rs1233870440 1905 dbSNP
rs910039859 1906 dbSNP
rs781397450 1919 dbSNP
rs11572062 1927 dbSNP
rs199896368 1931 dbSNP
rs1029757401 1937 dbSNP
rs955527085 1940 dbSNP
rs932960416 1945 dbSNP
rs558372440 1947 dbSNP
rs1401636123 1957 dbSNP
rs1460424231 1957 dbSNP
rs985700559 1973 dbSNP
rs1413723697 1980 dbSNP
rs1051863308 1991 dbSNP
rs1476632121 1992 dbSNP
rs1461043802 1994 dbSNP
rs1373985457 1997 dbSNP
rs891493133 2001 dbSNP
rs761814094 2007 dbSNP
rs1321669565 2008 dbSNP
rs1255063358 2010 dbSNP
rs1332843188 2014 dbSNP
rs1451038079 2015 dbSNP
rs1216240799 2020 dbSNP
rs1437479870 2033 dbSNP
rs1339887605 2038 dbSNP
rs1010555336 2041 dbSNP
rs13212313 2049 dbSNP
rs1225848270 2050 dbSNP
rs1269780120 2065 dbSNP
rs1372754322 2067 dbSNP
rs904341649 2067 dbSNP
rs968152181 2067 dbSNP
rs1338192783 2077 dbSNP
rs1220212131 2080 dbSNP
rs979086665 2082 dbSNP
rs1412115138 2091 dbSNP
rs1397712038 2111 dbSNP
rs1168386960 2118 dbSNP
rs1278829397 2123 dbSNP
rs1397121159 2135 dbSNP
rs1194495806 2136 dbSNP
rs1001335713 2138 dbSNP
rs576605295 2145 dbSNP
rs935044355 2147 dbSNP
rs1438354905 2152 dbSNP
rs544248973 2152 dbSNP
rs1202782153 2156 dbSNP
rs1451629325 2158 dbSNP
rs1349700404 2175 dbSNP
rs1014381358 2186 dbSNP
rs562452951 2189 dbSNP
rs775478911 2193 dbSNP
rs947848917 2200 dbSNP
rs1260552624 2208 dbSNP
rs1477075407 2210 dbSNP
rs1045424776 2211 dbSNP
rs1351674811 2217 dbSNP
rs887670145 2226 dbSNP
rs1425058724 2232 dbSNP
rs941362822 2234 dbSNP
rs1038350872 2238 dbSNP
rs370650460 2240 dbSNP
rs1377634727 2246 dbSNP
rs1174550320 2252 dbSNP
rs1472762510 2257 dbSNP
rs984762104 2259 dbSNP
rs1179049213 2269 dbSNP
rs542700252 2272 dbSNP
rs897246921 2274 dbSNP
rs770136293 2279 dbSNP
rs1317960291 2290 dbSNP
rs1179924154 2303 dbSNP
rs550598424 2305 dbSNP
rs1486563845 2307 dbSNP
rs1358844467 2308 dbSNP
rs1209038353 2311 dbSNP
rs994242172 2312 dbSNP
rs910156434 2314 dbSNP
rs1278613620 2315 dbSNP
rs1211971105 2318 dbSNP
rs1285861804 2319 dbSNP
rs1335328737 2323 dbSNP
rs964181406 2325 dbSNP
rs1051110916 2328 dbSNP
rs1354521803 2344 dbSNP
rs975579991 2345 dbSNP
rs1288332512 2348 dbSNP
rs562583201 2352 dbSNP
rs933056617 2354 dbSNP
rs1303820870 2357 dbSNP
rs541443531 2358 dbSNP
rs891334053 2368 dbSNP
rs1007005514 2369 dbSNP
rs114248956 2371 dbSNP
rs1411316163 2380 dbSNP
rs1156918860 2382 dbSNP
rs1042925775 2384 dbSNP
rs527564429 2391 dbSNP
rs1181094432 2395 dbSNP
rs1283516563 2414 dbSNP
rs1482122214 2416 dbSNP
rs1001284874 2421 dbSNP
rs1216804674 2424 dbSNP
rs1216046627 2425 dbSNP
rs55870047 2444 dbSNP
rs1327919006 2454 dbSNP
rs1265659664 2455 dbSNP
rs1055550532 2459 dbSNP
rs1337612267 2460 dbSNP
rs1313989687 2461 dbSNP
rs895684854 2465 dbSNP
rs1014742207 2466 dbSNP
rs1290917874 2470 dbSNP
rs35866882 2471 dbSNP
rs878957128 2471 dbSNP
rs1388053783 2480 dbSNP
rs951437436 2481 dbSNP
rs1463038753 2483 dbSNP
rs1005567009 2494 dbSNP
rs1163981280 2495 dbSNP
rs1017166266 2496 dbSNP
rs1186780364 2505 dbSNP
rs1464184572 2512 dbSNP
rs1245765864 2523 dbSNP
rs1215035233 2524 dbSNP
rs964283926 2534 dbSNP
rs975694608 2539 dbSNP
rs1158118399 2540 dbSNP
rs1378484160 2550 dbSNP
rs549123237 2557 dbSNP
rs922750426 2564 dbSNP
rs552102155 2574 dbSNP
rs780569521 2587 dbSNP
rs1298977051 2588 dbSNP
rs138460895 2592 dbSNP
rs1394037166 2596 dbSNP
rs1171608715 2602 dbSNP
rs1292913381 2605 dbSNP
rs1336146546 2616 dbSNP
rs987600671 2625 dbSNP
rs749603333 2627 dbSNP
rs1440929145 2629 dbSNP
rs1387942120 2630 dbSNP
rs1195107680 2644 dbSNP
rs1454379821 2645 dbSNP
rs1266030225 2654 dbSNP
rs978400529 2663 dbSNP
rs1355159564 2668 dbSNP
rs925661453 2671 dbSNP
rs149281840 2673 dbSNP
rs1055668238 2674 dbSNP
rs1279120691 2682 dbSNP
rs1344808478 2684 dbSNP
rs1199078568 2689 dbSNP
rs1236737872 2696 dbSNP
rs1258961916 2704 dbSNP
rs1300712444 2710 dbSNP
rs1385102769 2715 dbSNP
rs769225023 2729 dbSNP
rs949935122 2742 dbSNP
rs113377351 2764 dbSNP
rs1368457604 2776 dbSNP
rs1175178647 2778 dbSNP
rs762282165 2782 dbSNP
rs1047563689 2791 dbSNP
rs1196163021 2803 dbSNP
rs887209703 2810 dbSNP
rs1236456532 2815 dbSNP
rs1254605799 2824 dbSNP
rs1441578752 2833 dbSNP
rs1005676408 2836 dbSNP
rs1016935510 2857 dbSNP
rs899860310 2859 dbSNP
rs1159518264 2873 dbSNP
rs1377263940 2881 dbSNP
rs1464408763 2888 dbSNP
rs550217603 2891 dbSNP
rs1029937361 2893 dbSNP
rs1231166103 2894 dbSNP
rs955698073 2899 dbSNP
rs1445977079 2906 dbSNP
rs1329168496 2921 dbSNP
rs1288977524 2923 dbSNP
rs1378521241 2931 dbSNP
rs988334294 2933 dbSNP
rs1446850768 2935 dbSNP
rs1020414845 2937 dbSNP
rs1328990273 2940 dbSNP
rs1234878489 2941 dbSNP
rs1258145652 2943 dbSNP
rs1412029487 2945 dbSNP
rs1160601542 2946 dbSNP
rs1472567719 2948 dbSNP
rs1250183565 2951 dbSNP
rs1190064125 2953 dbSNP
rs374311613 2958 dbSNP
rs56331047 2962 dbSNP
rs1255817958 2974 dbSNP
rs978516424 2980 dbSNP
rs568483831 2982 dbSNP
rs925609182 2983 dbSNP
rs535982745 2990 dbSNP
rs991343743 2992 dbSNP
rs12529980 2995 dbSNP
rs566121878 2999 dbSNP
rs1331861512 3000 dbSNP
rs374265816 3004 dbSNP
rs1388861207 3006 dbSNP
rs1319326775 3013 dbSNP
rs1431666781 3018 dbSNP
rs1410405732 3020 dbSNP
rs1201205228 3022 dbSNP
rs949891055 3040 dbSNP
rs1240028237 3057 dbSNP
rs1046898115 3063 dbSNP
rs1378014944 3070 dbSNP
rs886973299 3073 dbSNP
rs941411271 3074 dbSNP
rs1292028385 3076 dbSNP
rs1210351382 3084 dbSNP
rs1344812736 3092 dbSNP
rs1168503429 3095 dbSNP
rs1229270866 3109 dbSNP
rs1365487112 3111 dbSNP
rs1038485857 3121 dbSNP
rs1440386937 3123 dbSNP
rs899809491 3129 dbSNP
rs1326171018 3136 dbSNP
rs1406430249 3138 dbSNP
rs1390598450 3141 dbSNP
rs1223056713 3144 dbSNP
rs1451658831 3151 dbSNP
rs1391026456 3154 dbSNP
rs1408267568 3154 dbSNP
rs200514298 3154 dbSNP
rs1387877232 3155 dbSNP
rs996862734 3162 dbSNP
rs1342598057 3172 dbSNP
rs1388173861 3173 dbSNP
rs1301489698 3174 dbSNP
rs1225699809 3178 dbSNP
rs1030292331 3181 dbSNP
rs1274960007 3186 dbSNP
rs891380323 3207 dbSNP
rs1010273750 3209 dbSNP
rs1021115598 3210 dbSNP
rs968217479 3211 dbSNP
rs1199749181 3213 dbSNP
rs147988704 3214 dbSNP
rs1032742792 3218 dbSNP
rs958338538 3219 dbSNP
rs566544611 3231 dbSNP
rs558169462 3233 dbSNP
rs1211894306 3241 dbSNP
rs1477699618 3249 dbSNP
rs576540083 3253 dbSNP
rs1184238765 3257 dbSNP
rs1483288315 3259 dbSNP
rs537260264 3262 dbSNP
rs183380132 3264 dbSNP
rs1202713270 3272 dbSNP
rs1313612949 3275 dbSNP
rs376535680 3282 dbSNP
rs142321409 3283 dbSNP
rs1218136531 3285 dbSNP
rs908351355 3289 dbSNP
rs1478113508 3292 dbSNP
rs541558064 3294 dbSNP
rs1351535853 3305 dbSNP
rs559716199 3308 dbSNP
rs765317308 3309 dbSNP
rs1361116595 3310 dbSNP
rs35350278 3311 dbSNP
rs921357067 3316 dbSNP
rs1359484824 3318 dbSNP
rs932599062 3319 dbSNP
rs1472890471 3320 dbSNP
rs1411090485 3342 dbSNP
rs187547649 3343 dbSNP
rs545654173 3344 dbSNP
rs1484077770 3347 dbSNP
rs518982 3350 dbSNP
rs891155000 3351 dbSNP
rs1009809237 3354 dbSNP
rs1228434731 3356 dbSNP
rs1312588082 3361 dbSNP
rs1288212197 3363 dbSNP
rs531508490 3368 dbSNP
rs1320044651 3371 dbSNP
rs1247062572 3379 dbSNP
rs549690469 3391 dbSNP
rs1488087615 3394 dbSNP
rs1447546590 3398 dbSNP
rs1214650592 3403 dbSNP
rs1265089588 3405 dbSNP
rs1446728109 3406 dbSNP
rs1387832357 3408 dbSNP
rs796502479 3428 dbSNP
rs1425402541 3430 dbSNP
rs1414208642 3431 dbSNP
rs200133308 3431 dbSNP
rs1471616424 3436 dbSNP
rs1249435528 3443 dbSNP
rs1425100197 3444 dbSNP
rs1464040968 3447 dbSNP
rs1268125280 3456 dbSNP
rs1001003308 3462 dbSNP
rs1323931576 3469 dbSNP
rs541112 3473 dbSNP
rs958453857 3474 dbSNP
rs1417502301 3484 dbSNP
rs760328628 3490 dbSNP
rs1023958790 3492 dbSNP
rs1362883020 3492 dbSNP
rs1431898347 3497 dbSNP
rs765958544 3506 dbSNP
rs1459356958 3511 dbSNP
rs1350345054 3513 dbSNP
rs971492379 3514 dbSNP
rs1377612101 3540 dbSNP
rs1422458831 3540 dbSNP
rs1391699540 3542 dbSNP
rs1188802645 3546 dbSNP
rs1446288702 3550 dbSNP
rs1245643618 3551 dbSNP
rs1192379037 3554 dbSNP
rs1275743525 3555 dbSNP
rs1489772680 3558 dbSNP
rs1266480355 3568 dbSNP
rs1221313868 3570 dbSNP
rs982694988 3573 dbSNP
rs1490336664 3593 dbSNP
rs1398231602 3599 dbSNP
rs529399355 3609 dbSNP
rs9349286 3619 dbSNP
rs1270462546 3620 dbSNP
rs1353014421 3629 dbSNP
rs1388548265 3636 dbSNP
rs962502339 3645 dbSNP
rs973903652 3652 dbSNP
rs921137907 3656 dbSNP
rs932715431 3659 dbSNP
rs1288388739 3660 dbSNP
rs1168892860 3661 dbSNP
rs1051646478 3665 dbSNP
rs912547597 3673 dbSNP
rs56371537 3678 dbSNP
rs945388567 3679 dbSNP
rs759214068 3686 dbSNP
rs1042617750 3689 dbSNP
rs1191116243 3694 dbSNP
rs571653688 3694 dbSNP
rs542613468 3695 dbSNP
rs1206246541 3702 dbSNP
rs1249781971 3702 dbSNP
rs1235592063 3704 dbSNP
rs1312846047 3704 dbSNP
rs1300559147 3714 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggguggucgacgaGGGACCGGGu 5'
                       :|:|||||| 
Target 5' ----------caaUCUUGGCCCa 3'
 		1 - 13
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293/HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1067870. RNA binding protein: AGO2. Condition:Ago2 IP-seq (mitotic cells) ...

- Kishore S; Gruber AR; Jedlinski DJ; Syed et al., 2013, Genome biology.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggguGGUCGACG--AGGGACCGGGu 5'
              ||| ||||   |:||| |:| 
Target 5' -ggcCCA-CUGCAACCUCUGCCUCc 3'
 		1 - 23
Article - Kishore S; Gruber AR; Jedlinski DJ; Syed et al.
- Genome biology, 2013
BACKGROUND: In recent years, a variety of small RNAs derived from other RNAs with well-known functions such as tRNAs and snoRNAs, have been identified. The functional relevance of these RNAs is largely unknown. To gain insight into the complexity of snoRNA processing and the functional relevance of snoRNA-derived small RNAs, we sequence long and short RNAs, small RNAs that co-precipitate with the Argonaute 2 protein and RNA fragments obtained in photoreactive nucleotide-enhanced crosslinking and immunoprecipitation (PAR-CLIP) of core snoRNA-associated proteins. RESULTS: Analysis of these data sets reveals that many loci in the human genome reproducibly give rise to C/D box-like snoRNAs, whose expression and evolutionary conservation are typically less pronounced relative to the snoRNAs that are currently cataloged. We further find that virtually all C/D box snoRNAs are specifically processed inside the regions of terminal complementarity, retaining in the mature form only 4-5 nucleotides upstream of the C box and 2-5 nucleotides downstream of the D box. Sequencing of the total and Argonaute 2-associated populations of small RNAs reveals that despite their cellular abundance, C/D box-derived small RNAs are not efficiently incorporated into the Ago2 protein. CONCLUSIONS: We conclude that the human genome encodes a large number of snoRNAs that are processed along the canonical pathway and expressed at relatively low levels. Generation of snoRNA-derived processing products with alternative, particularly miRNA-like, functions appears to be uncommon.
LinkOut: [PMID: 23706177]
CLIP-seq Support 1 for dataset GSM1067870
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293/HeLa / Ago2 IP-seq (mitotic cells)
Location of target site ENST00000371477.3 | 3UTR | GGCCCACUGCAACCUCUGCCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23706177 / GSE43666
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000371477.3 | 3UTR | CAAUCUUGGCCCACUGCAACCUCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
87 hsa-miR-4640-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100106 ABT1 activator of basal transcription 1 2 8
MIRT248144 LMBR1L limb development membrane protein 1 like 2 2
MIRT327062 KLHL15 kelch like family member 15 2 2
MIRT347231 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT450221 CENPN centromere protein N 2 2
MIRT451264 NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 2 2
MIRT452701 C1orf226 chromosome 1 open reading frame 226 2 2
MIRT453212 CERS1 ceramide synthase 1 2 2
MIRT454822 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT454883 RAD50 RAD50 double strand break repair protein 2 2
MIRT455783 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT455858 TMEM254 transmembrane protein 254 2 2
MIRT457615 UPK3BL uroplakin 3B like 1 2 2
MIRT457822 ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 2 4
MIRT458344 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458376 ITM2C integral membrane protein 2C 2 2
MIRT458928 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT459066 WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 2 2
MIRT460138 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT460818 FSTL4 follistatin like 4 2 2
MIRT461285 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 2
MIRT462738 EFNB1 ephrin B1 2 2
MIRT464556 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT477910 DUSP2 dual specificity phosphatase 2 2 2
MIRT479073 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 4
MIRT479534 CDC5L cell division cycle 5 like 2 4
MIRT485628 EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2 2
MIRT489896 PPIC peptidylprolyl isomerase C 2 4
MIRT490737 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT491201 MLLT1 MLLT1, super elongation complex subunit 2 4
MIRT492681 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT494593 ATG7 autophagy related 7 2 2
MIRT495061 PADI3 peptidyl arginine deiminase 3 2 4
MIRT496623 TMEM67 transmembrane protein 67 2 2
MIRT497177 ZBTB40 zinc finger and BTB domain containing 40 2 2
MIRT498217 TLN2 talin 2 2 2
MIRT498306 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT499668 NPHP3 nephrocystin 3 2 2
MIRT508080 ANKRD52 ankyrin repeat domain 52 2 2
MIRT509707 ANKRD23 ankyrin repeat domain 23 2 2
MIRT509841 FOS Fos proto-oncogene, AP-1 transcription factor subunit 2 2
MIRT512814 ARRDC2 arrestin domain containing 2 2 2
MIRT513353 SLIT1 slit guidance ligand 1 2 2
MIRT514293 FXYD5 FXYD domain containing ion transport regulator 5 2 2
MIRT516598 FAM89A family with sequence similarity 89 member A 2 4
MIRT516616 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT518348 CCL5 C-C motif chemokine ligand 5 2 2
MIRT520130 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT522072 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT526461 OSBPL5 oxysterol binding protein like 5 2 2
MIRT528278 MBL2 mannose binding lectin 2 2 2
MIRT534844 RAB15 RAB15, member RAS oncogene family 2 4
MIRT542245 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT543299 ZNF585B zinc finger protein 585B 2 2
MIRT552456 ZNF410 zinc finger protein 410 2 2
MIRT553641 TJAP1 tight junction associated protein 1 2 2
MIRT557103 HOXA3 homeobox A3 2 2
MIRT570782 FANCA Fanconi anemia complementation group A 2 2
MIRT630912 ZMAT2 zinc finger matrin-type 2 2 2
MIRT631034 ZNF878 zinc finger protein 878 2 2
MIRT639017 AAK1 AP2 associated kinase 1 2 2
MIRT648596 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT648939 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2 2
MIRT652834 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT659347 CSRP1 cysteine and glycine rich protein 1 2 2
MIRT664163 APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F 2 2
MIRT670511 ZSCAN22 zinc finger and SCAN domain containing 22 2 2
MIRT671246 TMEM41B transmembrane protein 41B 2 2
MIRT672120 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT672313 CD3D CD3d molecule 2 2
MIRT672543 BRMS1L breast cancer metastasis-suppressor 1 like 2 2
MIRT673036 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT673814 DARS aspartyl-tRNA synthetase 2 2
MIRT674858 GINM1 glycoprotein integral membrane 1 2 2
MIRT674970 SH3BP2 SH3 domain binding protein 2 2 2
MIRT675185 KIF1C kinesin family member 1C 2 2
MIRT675219 UGDH UDP-glucose 6-dehydrogenase 2 2
MIRT675558 MED16 mediator complex subunit 16 2 2
MIRT682566 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT684640 PDE4C phosphodiesterase 4C 2 2
MIRT689722 ATXN2 ataxin 2 2 2
MIRT693594 SLC39A1 solute carrier family 39 member 1 2 2
MIRT704745 CDKN2B cyclin dependent kinase inhibitor 2B 2 2
MIRT712779 ZNF154 zinc finger protein 154 2 2
MIRT718118 OTOF otoferlin 2 2
MIRT720115 SAMD4A sterile alpha motif domain containing 4A 2 2
MIRT720275 EIF1AD eukaryotic translation initiation factor 1A domain containing 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4640 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4640 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4640 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4640-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4640-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4640-5p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-4640-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4640-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4640-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4640-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4640-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4640-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4640-5p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4640-5p Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)

Error report submission