miRTarBase - #MIRT480759


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pre-miRNA Information
pre-miRNA hsa-mir-4793   
Genomic Coordinates chr3: 48644194 - 48644280
Description Homo sapiens miR-4793 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4793-3p
Sequence 58| UCUGCACUGUGAGUUGGCUGGCU |80
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM5899925 14 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs779602935 6 dbSNP
rs757908486 7 dbSNP
rs1422853760 15 dbSNP
rs377721296 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BMP3   
Synonyms BMP-3A
Description bone morphogenetic protein 3
Transcript NM_001201   
Expression
Putative miRNA Targets on BMP3
3'UTR of BMP3
(miRNA target sites are highlighted)		 
>BMP3|NM_001201|3'UTR
   1 CCTGGCAAAGAACTCATTTGAATGCTTAATTCAATCATTAGTTTATTTTTATGGACTTCTTCCTGTTTTTTTTTTTTTTT
  81 TTTTTGCACTGCCAATGCATTTTGTTTCAAAAGATTATTTCTATAGTCAGAGGGGAATGAGCAAATAGACTGAAGATTGC
 161 CACCAAGGAAAAGAACTGTATTTGTTTCTGAATGTAACTTAAAGCAAGATTTTTAGTAAATATGGACATCTATTTCTCTT
 241 TTTGTAATCAAACACAACAACTTATCAAACTGTTTTTAGAACTGTTAGAGAACACACTGGTTTATTTTTGTAATGTTCTT
 321 TGAAAACAGAATGGAGAAGCAGCAATAGCTTGTCATTTATCTCATTTAATGACTAATGGGAAATAGAGAACAATTTCGCG
 401 TTTTGAATTAGGCTTATTGCCTTAGAATCCTGAGAAAGTGCTAAATAATCAACTCTGATGTTTTTCTTAAGTTCTTGAGA
 481 CTCTTGTTTATCCTTGTTTTTCCTCCACAAGTCATTGTCTAAGTGTAATGGAAAGTTTATGCTGAGCGTTAGTGTGTATG
 561 TATGTGCGTACATGCGCCAGGTGCCTGTGCCCTCTGTAGGATGGTTTGCTTAATATGGTTTTATAATTCAGTTTACACAG
 641 GATTCTTTATTTTTTTTAATTTTGTATTTTGGCAAACACCATTCAGTTATAAGAACTTTGCCAAATATGATAGAATAATT
 721 CAAGAGCATATACAGAGAGTTACCACTTGACCCAGCTATTTAATTGCAAATACAGTTGTTTTCATTTCATTTCCTACCAG
 801 AAAAAGGAATCAGAAACCTAGTTTTTGAAAACACAAGTGTAATTCCTCTTTTGTACTTCTTTTTCACAAATGCTTTTATT
 881 TATTCTAAATTGAATTTAAAAATCCTTCCTAAAGCCATTAACTCTTTAATTCTCCTGATATGCCTTTACTTCCTATGAAG
 961 TTATTGGTAGATGTTGAGGCCCAAAAACTGGTAGAATATTGAAGATCTTCTTAAATGACCAATTTAACCATAACCAAATA
1041 TTGAATATCATTCTTCAGTCACATCTAAGTCAGGCACTTTTTCACATAGATCAGGGCTTTTGGCTCAGTCACGAAATCTA
1121 CAAGTTAGCAAAGCTTACAAAACATTATTCGTCAGGTATGGGAATCAAATATAGACACTTGTTTGTCTTTGCTTTCCATT
1201 TCTATGTGTCACATACATATATGTGTCCTCTTATAACTTTAGTCTTCAAAATTATTTCAATATCCTTCTTCTCACTATAT
1281 TTATTTGTGTGATGGAAATGCTTTCAGGCCGTAGATCATTGTTGGTGTTAATCTGTGGTTAATCCTCATTTTAGTTCCGT
1361 CTTATCTGATACTTAGAAATATCTCAGCCATTTTGGAGGCTGTGCAGTATCAGAAGACGTGGAGTTTGTTCTGTCTCTGC
1441 CTGTAGCTAATTATGGTGGTTCAGTCATTTAATAAATATGTTTTGAGCATCTATTTTGTGAAAGGCACTGTGTTACCTGT
1521 GTGTCTTTAGTGTCCTCACTGGTAAAATGAAGAGGCTGGCCATGAGCTGGAAGGGTTAAGTTTATAATTCCAGCTATTTC
1601 ACACCCGTCTTCCTTGAAGGAATGATAGTGATAGATATAAAAACACTGTAAGTCCCTCTTTTAATAAACTAAATGAAAGA
1681 ACATCCTATACTTCGCTGTTTGTAAATTAGTATGGCATTCGCTTTGGTTTAAGTGGTATTTTATTGCAAACCCATTAAAA
1761 GAATAACTCATGAAAAGAAGCTCTTTGACACCTTGGGGTACACAAATGTTGGTGTGGGTGTGTGTTAATTCTGTGAGTGA
1841 GACACACCAGTTCTAAAAAAAATGAGTGAAGTTCTGGTGCCTGAGTTACCATGCTTTCTTCTAGTTCTTACAGTAGCATA
1921 AAATTAAAGATTCAAAGTGAGATGGAGGATAAAATTACTTTTTAATACATGTTCTCAAACATTTGAAAATAAAAGTATAT
2001 GATAGAAGGGGGCCAGAGTGTGGCCACCATCCTGATCGTACTGTTTTTCAATAAAGAAAACTTTTTCATTGGTAGATTTG
2081 GTGAAATTCTAAATTTAGGTTTTTTTCTAGAGCTGTATCAACCAAAACTTCTGGCAATTCCCAGTATCACTTCTTAGCCT
2161 TCTTATATCCAAATGCCTGTTTATTACCTTTCTTAATTTGAATCAATGCCTAGTTATTACAGATTGCACCCCACAATGGC
2241 CAAAAACCCACTACATAATAAAATTTACAGGTACTAACTAGTTAAGATTATATTTTAAGTAGCAATTGATATAAAATTAC
2321 AACACAATGAAAGAACTTGGGTAATCTCTTAGCAATGGAAATAGGTTTTAACCAGCAGTTTTTCTGGGTGCTTTGTAACT
2401 ATCATTTTACTAATGAATTGAGGATGTATTATGGTTTAAATTGGAAGAGTTTTATTCCCAAAGAATAAAGCAAGATTATC
2481 TTTCAGTAGTAGAGATTGAAGTAAATGTATTAATATTTTAATTAATACAGATTTACTAAGAGTAGTTAGAAAATTTAGTA
2561 AGTGCCTGTTTTACAAATTGTTAGGTACTAGTTTCTGTATAATTCCTACACAGAAGCTTTAGAAATCTCCTGATATTAAA
2641 TTATTAAATTGGCATTCATGAAAAGAGAAGCTACAATTATAAACTCCATTTGCTAAATCATGCATAATACTCTCTCTCTC
2721 TCTTCCCCCACAAGTAATCTCTCTACCCCATGCAGTGTGCACACACACACACACACAGTCAGTTACTGAAAAAAATAATT
2801 CTTTTTCTTTTTTTTTTTAAATGGAGTTTCACTCTTGTCGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCCCACTGCA
2881 ACCTCCACCTCCCAGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGTCCGCCACCATGCC
2961 TGGCTAATTTTTTTATTTGATAAAAAGAATTCTTTTTCTCAATAACTGTTCTCTTGAATTCAAATTAAGGGACTGCCAAA
3041 GTCAATTAGAATATTTTAAAAATACTTTGTTGTAACCTGTGTAAATAATATACAATTTACAGGATTTGGGATTGTAGAAC
3121 TTAAACTGGAAGACTGGATTCCTCAGATCTCAGGACTATAACATTCCAGATAAATTTTTACATTCCCTTTGCTGTATATT
3201 AACTGATGATCATTTATATGTTAAGATTTTTTACCTTAATATTTCTGAATAAAACTCTTATTGCCCATTTAATATTTTCA
3281 TAGGCAATCAAATGTGAGTAATACTGCTAAGAGTCTGATTTATTAAAAATATTTGTATAATTCATTCAGTTTAGTTTTTC
3361 AGTTTAGTCTTTCTGCTTTCACTTTTCTCTGTGCTAACAAGTAACTAATGTCTGGGCATTGACTTCTTATTGAATCAAAG
3441 TTGGGTTAGGCATAGCTATGCACACCTGATGTGTAAGATTAAAGAAGAGATTAAATAAGAAATCTTGGGTAAGTTGGACT
3521 TTTCTGTATAGCTCTTTTTTCCTCTGAGTTGTATTTTAATGTAGTTTATAAGTGATAAAATGATCCTTGTTTTCTAAAAG
3601 CCAGTCCTTCCCTTCAGCTTTCCACAGTTTCTGTAAATGTTTAATACTTGTACAGTCAATGGCAATTTTAAATATATATA
3681 TATATATAATATATGTATATGGAAAAGGTTCAAAGATGCTTTTAATTTATTTAATGACTATTGCCTTCCTATAATAATAA
3761 TTTTCATCCTTAATTATGATAATACTTTTAGCAAGAAAAATTCCTTTTTACTACAGTTTTTAGATGCAAAATGCAGTTTG
3841 GTTCTTTAGTCAAATCCACTTAGAGGGTATATTGCAGTGAAACTGTGAAGGATACTTCACTACCAATGTATAAGCTTTGT
3921 TGAATTTGTATCATTTTCTTTCAGTAATGAAAAGCTATTCATTATACAGTATGGAAATAAAAATTGCTTCATTGACCATT
4001 CATTTTTACTTATTGGGAAATACTATATTTCCAGACATTTTCAAGTGTGCTGCATTTAAAAGAGGTAATAAAGCTTAAGC
4081 ATAGAGTTG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucGGUCGGUUGAGUGUCACGUCu 5'
            :|: |||:  :: ||||||| 
Target 5' tgTCGCCCAGGCTGGAGTGCAGt 3'
 2836 - 2858 153.00 -19.70
2 
miRNA  3' ucGGUCGGUUGAG----UGUCACGUCu 5'
            :|||||| :|:    :| |||||| 
Target 5' tcTCAGCCATTTTGGAGGCTGTGCAGt 3'
 1382 - 1408 135.00 -19.10
3 
miRNA  3' ucgGUCGG----UUGAGUGUCACGUCu 5'
             |||::    :|: || | ||||| 
Target 5' ctaCAGTTTTTAGATGCAAAATGCAGt 3'
 3811 - 3837 122.00 -10.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30477494 5 COSMIC
COSN31573348 11 COSMIC
COSN30189225 51 COSMIC
COSN30480400 55 COSMIC
COSN25638056 58 COSMIC
COSN30145476 110 COSMIC
COSN30127640 156 COSMIC
COSN26850459 168 COSMIC
COSN31599760 209 COSMIC
COSN31535158 231 COSMIC
COSN31529218 280 COSMIC
COSN31516754 317 COSMIC
COSN31489114 330 COSMIC
COSN8618108 434 COSMIC
COSN31489262 531 COSMIC
COSN29315847 658 COSMIC
COSN8491428 685 COSMIC
COSN2477631 722 COSMIC
COSN14820482 726 COSMIC
COSN31566122 767 COSMIC
COSN31568433 813 COSMIC
COSN32063667 823 COSMIC
COSN5578751 859 COSMIC
COSN2046634 1088 COSMIC
COSN15582917 1339 COSMIC
COSN31962297 1358 COSMIC
COSN7844682 1720 COSMIC
COSN8349877 2045 COSMIC
COSN22276237 2063 COSMIC
COSN29100695 2088 COSMIC
COSN15757461 2144 COSMIC
COSN20091066 2200 COSMIC
COSN21693519 2309 COSMIC
COSN216741 2344 COSMIC
COSN2046635 2348 COSMIC
COSN2046636 2519 COSMIC
COSN15400832 2659 COSMIC
COSN27303853 2723 COSMIC
COSN20100264 2796 COSMIC
COSN31609444 2993 COSMIC
COSN15668393 3059 COSMIC
COSN31535814 3093 COSMIC
COSN27320104 3175 COSMIC
COSN31545037 3193 COSMIC
COSN2046637 3321 COSMIC
COSN31522597 3338 COSMIC
COSN31607522 3348 COSMIC
COSN31596132 3351 COSMIC
COSN31545827 3361 COSMIC
COSN31536680 3457 COSMIC
COSN31521205 3505 COSMIC
COSN28201551 3676 COSMIC
COSN6581980 3850 COSMIC
COSN29878150 3884 COSMIC
COSN2046638 3895 COSMIC
COSN15662943 3950 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs530695825 4 dbSNP
rs984578913 7 dbSNP
rs781457224 17 dbSNP
rs750673028 18 dbSNP
rs1418711632 24 dbSNP
rs990400627 28 dbSNP
rs149057133 30 dbSNP
rs780000725 36 dbSNP
rs1424640063 39 dbSNP
rs749181644 40 dbSNP
rs1387684158 42 dbSNP
rs1210416724 51 dbSNP
rs754989944 53 dbSNP
rs1193673609 54 dbSNP
rs1252253209 63 dbSNP
rs1203461191 64 dbSNP
rs1307368735 65 dbSNP
rs375448689 65 dbSNP
rs1042122004 66 dbSNP
rs1187402466 66 dbSNP
rs1254261142 66 dbSNP
rs1415758639 66 dbSNP
rs1421067730 66 dbSNP
rs1425540677 66 dbSNP
rs1460286637 66 dbSNP
rs1473003317 66 dbSNP
rs1491333140 66 dbSNP
rs1491437614 66 dbSNP
rs371743242 66 dbSNP
rs60606505 66 dbSNP
rs1175799668 67 dbSNP
rs386400624 67 dbSNP
rs1197555520 69 dbSNP
rs1375854953 70 dbSNP
rs1039242104 71 dbSNP
rs1455575899 71 dbSNP
rs1224397903 72 dbSNP
rs901778893 73 dbSNP
rs1232151002 74 dbSNP
rs933211453 74 dbSNP
rs1289855744 77 dbSNP
rs1389418731 80 dbSNP
rs1372320002 83 dbSNP
rs1491059100 85 dbSNP
rs1157241773 86 dbSNP
rs1459379696 86 dbSNP
rs1426795614 87 dbSNP
rs1433627501 88 dbSNP
rs1296617981 92 dbSNP
rs1457857196 97 dbSNP
rs906305260 98 dbSNP
rs1391974845 99 dbSNP
rs1323058176 100 dbSNP
rs879155979 105 dbSNP
rs1193352910 109 dbSNP
rs1467471593 110 dbSNP
rs1252930947 115 dbSNP
rs939129699 118 dbSNP
rs7661611 120 dbSNP
rs867796067 122 dbSNP
rs868717809 123 dbSNP
rs1236419791 128 dbSNP
rs1316042669 131 dbSNP
rs1301641328 144 dbSNP
rs757233501 146 dbSNP
rs1442850674 150 dbSNP
rs903214049 156 dbSNP
rs1368636844 160 dbSNP
rs529438935 168 dbSNP
rs1435777962 174 dbSNP
rs1055343198 177 dbSNP
rs190102711 184 dbSNP
rs1453316478 185 dbSNP
rs1378428300 194 dbSNP
rs1178608103 197 dbSNP
rs1452986108 206 dbSNP
rs1033130291 224 dbSNP
rs369426764 225 dbSNP
rs1252633349 227 dbSNP
rs1263216479 228 dbSNP
rs1202860080 229 dbSNP
rs1256253985 232 dbSNP
rs1480792650 233 dbSNP
rs1345434532 234 dbSNP
rs1208711067 239 dbSNP
rs879125438 242 dbSNP
rs1013088209 243 dbSNP
rs1016840639 254 dbSNP
rs897159518 261 dbSNP
rs1250648924 270 dbSNP
rs1316224043 272 dbSNP
rs1381735777 273 dbSNP
rs1403119465 274 dbSNP
rs1304840481 287 dbSNP
rs1433136530 291 dbSNP
rs1169700830 294 dbSNP
rs778775540 298 dbSNP
rs994151226 300 dbSNP
rs1469741475 305 dbSNP
rs1190341264 310 dbSNP
rs1194141701 316 dbSNP
rs1427443574 328 dbSNP
rs1023530103 330 dbSNP
rs979411277 340 dbSNP
rs1212555914 345 dbSNP
rs151144163 347 dbSNP
rs1172281151 349 dbSNP
rs981715044 350 dbSNP
rs1341311167 355 dbSNP
rs1268366816 364 dbSNP
rs1375001471 364 dbSNP
rs1462742670 369 dbSNP
rs1226729979 373 dbSNP
rs1341106142 376 dbSNP
rs1026565917 379 dbSNP
rs534979298 382 dbSNP
rs1413164429 389 dbSNP
rs950398220 392 dbSNP
rs7678312 399 dbSNP
rs182988931 400 dbSNP
rs1018817092 401 dbSNP
rs1394924118 413 dbSNP
rs1167816343 414 dbSNP
rs367727512 414 dbSNP
rs908967117 418 dbSNP
rs1189525899 421 dbSNP
rs957531908 430 dbSNP
rs990400429 433 dbSNP
rs1380880961 435 dbSNP
rs535421442 437 dbSNP
rs1182572213 438 dbSNP
rs1439373693 449 dbSNP
rs1298260108 450 dbSNP
rs943091804 451 dbSNP
rs974618737 452 dbSNP
rs1357052696 454 dbSNP
rs978134417 457 dbSNP
rs1231544342 458 dbSNP
rs537327415 462 dbSNP
rs927670315 466 dbSNP
rs557572442 487 dbSNP
rs544135640 497 dbSNP
rs1307693779 507 dbSNP
rs1334330640 508 dbSNP
rs574148887 515 dbSNP
rs1328674113 517 dbSNP
rs933135840 531 dbSNP
rs939059265 540 dbSNP
rs1397326999 541 dbSNP
rs1243666569 546 dbSNP
rs1459430065 547 dbSNP
rs1416662019 548 dbSNP
rs1270919874 549 dbSNP
rs1470985754 553 dbSNP
rs1230947716 559 dbSNP
rs1054890039 560 dbSNP
rs1452054652 562 dbSNP
rs894974624 567 dbSNP
rs1329470622 568 dbSNP
rs1336233645 576 dbSNP
rs536355843 577 dbSNP
rs1225672404 580 dbSNP
rs1348895457 582 dbSNP
rs1213785811 585 dbSNP
rs1279266179 592 dbSNP
rs554437350 593 dbSNP
rs574342813 595 dbSNP
rs934667342 596 dbSNP
rs1054825183 604 dbSNP
rs1373762270 617 dbSNP
rs140064899 640 dbSNP
rs1393066164 641 dbSNP
rs746656016 642 dbSNP
rs897107001 647 dbSNP
rs1454572843 650 dbSNP
rs994056313 650 dbSNP
rs1262230109 652 dbSNP
rs1396707157 658 dbSNP
rs1191649795 665 dbSNP
rs1423057577 666 dbSNP
rs1023036043 680 dbSNP
rs1248720830 688 dbSNP
rs1030051858 690 dbSNP
rs754516085 695 dbSNP
rs368040632 708 dbSNP
rs1007349927 710 dbSNP
rs1350463196 711 dbSNP
rs1003034703 717 dbSNP
rs1234182043 724 dbSNP
rs72870289 729 dbSNP
rs1366643544 735 dbSNP
rs1018401209 740 dbSNP
rs1343032100 752 dbSNP
rs1317158582 759 dbSNP
rs1388530640 761 dbSNP
rs185811219 765 dbSNP
rs1011782546 767 dbSNP
rs1171601282 771 dbSNP
rs1290966012 773 dbSNP
rs1453656695 774 dbSNP
rs1420153750 779 dbSNP
rs1363047738 785 dbSNP
rs575538079 788 dbSNP
rs1020479911 790 dbSNP
rs879511674 806 dbSNP
rs544177869 813 dbSNP
rs6831641 815 dbSNP
rs1486808817 817 dbSNP
rs78629796 820 dbSNP
rs990973413 836 dbSNP
rs1267005763 837 dbSNP
rs5004402 840 dbSNP
rs1213369887 845 dbSNP
rs559854321 852 dbSNP
rs1217807659 854 dbSNP
rs1261261699 860 dbSNP
rs377133176 865 dbSNP
rs941183479 870 dbSNP
rs1415016109 872 dbSNP
rs1185532377 881 dbSNP
rs1310784540 889 dbSNP
rs1433890712 891 dbSNP
rs1354994223 892 dbSNP
rs1038137904 894 dbSNP
rs974922861 896 dbSNP
rs923020227 899 dbSNP
rs1188827701 913 dbSNP
rs954576667 924 dbSNP
rs147122908 936 dbSNP
rs1187632470 939 dbSNP
rs1481146668 943 dbSNP
rs1188718130 948 dbSNP
rs1203024131 951 dbSNP
rs1307493923 980 dbSNP
rs1271602025 982 dbSNP
rs923859634 983 dbSNP
rs1495637 985 dbSNP
rs1291089159 988 dbSNP
rs1495636 992 dbSNP
rs1346320861 996 dbSNP
rs537794780 997 dbSNP
rs1434418605 1000 dbSNP
rs1439928007 1007 dbSNP
rs1353862238 1013 dbSNP
rs550946681 1021 dbSNP
rs1006917690 1024 dbSNP
rs1039799631 1032 dbSNP
rs893198011 1047 dbSNP
rs914585032 1052 dbSNP
rs1415073377 1068 dbSNP
rs948747153 1076 dbSNP
rs1020426049 1085 dbSNP
rs1370473458 1098 dbSNP
rs77192228 1109 dbSNP
rs1003530031 1113 dbSNP
rs866012916 1114 dbSNP
rs536418048 1116 dbSNP
rs1208444483 1123 dbSNP
rs1047904362 1124 dbSNP
rs1243594733 1125 dbSNP
rs886706258 1145 dbSNP
rs1317212388 1151 dbSNP
rs73831278 1152 dbSNP
rs1221870794 1156 dbSNP
rs1372480763 1163 dbSNP
rs1016499609 1173 dbSNP
rs1326465080 1175 dbSNP
rs990528808 1178 dbSNP
rs916259552 1179 dbSNP
rs1454444143 1180 dbSNP
rs962411635 1207 dbSNP
rs1211815569 1213 dbSNP
rs764165422 1214 dbSNP
rs1232546146 1216 dbSNP
rs1157317833 1222 dbSNP
rs1418891197 1223 dbSNP
rs1396107045 1224 dbSNP
rs1196021567 1231 dbSNP
rs964769867 1237 dbSNP
rs1250591934 1238 dbSNP
rs1479666806 1240 dbSNP
rs1485956770 1242 dbSNP
rs1262157906 1245 dbSNP
rs879486114 1247 dbSNP
rs1409352538 1265 dbSNP
rs1303956661 1275 dbSNP
rs1236405983 1288 dbSNP
rs572638217 1294 dbSNP
rs929858550 1308 dbSNP
rs1051437135 1311 dbSNP
rs776509819 1312 dbSNP
rs1435750457 1316 dbSNP
rs1376427021 1320 dbSNP
rs1327695799 1326 dbSNP
rs1395020790 1334 dbSNP
rs1453045708 1334 dbSNP
rs1197488801 1336 dbSNP
rs912511723 1337 dbSNP
rs942627466 1348 dbSNP
rs1184393712 1349 dbSNP
rs55807732 1355 dbSNP
rs1298309115 1359 dbSNP
rs1345589293 1360 dbSNP
rs954420288 1360 dbSNP
rs1255376916 1366 dbSNP
rs977913191 1380 dbSNP
rs191716079 1382 dbSNP
rs1238188846 1385 dbSNP
rs765202901 1387 dbSNP
rs1041858501 1395 dbSNP
rs903347851 1399 dbSNP
rs1356341225 1401 dbSNP
rs74904047 1402 dbSNP
rs1036339555 1407 dbSNP
rs1227412686 1414 dbSNP
rs989825613 1416 dbSNP
rs916494983 1419 dbSNP
rs1272476287 1420 dbSNP
rs1477259612 1423 dbSNP
rs948737776 1425 dbSNP
rs1013602853 1428 dbSNP
rs1023216522 1454 dbSNP
rs962360054 1457 dbSNP
rs973783226 1459 dbSNP
rs1206706430 1460 dbSNP
rs544501234 1464 dbSNP
rs1341465517 1465 dbSNP
rs1249621290 1471 dbSNP
rs1044379440 1479 dbSNP
rs1218103482 1490 dbSNP
rs1468406245 1494 dbSNP
rs928723224 1495 dbSNP
rs1025384457 1502 dbSNP
rs1192265160 1503 dbSNP
rs183879078 1507 dbSNP
rs138526836 1511 dbSNP
rs938723170 1514 dbSNP
rs1454926476 1517 dbSNP
rs1047831986 1520 dbSNP
rs1167761695 1521 dbSNP
rs912404948 1533 dbSNP
rs942596010 1543 dbSNP
rs1393578605 1544 dbSNP
rs975336556 1549 dbSNP
rs188884739 1552 dbSNP
rs1006388379 1558 dbSNP
rs1464680879 1560 dbSNP
rs1038392468 1563 dbSNP
rs900717519 1571 dbSNP
rs1166613274 1572 dbSNP
rs144041262 1581 dbSNP
rs1367670578 1585 dbSNP
rs1170496542 1597 dbSNP
rs1439430755 1601 dbSNP
rs750973588 1607 dbSNP
rs528636235 1608 dbSNP
rs551901058 1609 dbSNP
rs938776940 1616 dbSNP
rs755061629 1624 dbSNP
rs1280447765 1628 dbSNP
rs999259819 1646 dbSNP
rs1030688925 1647 dbSNP
rs1334471069 1649 dbSNP
rs192472472 1649 dbSNP
rs1331230617 1657 dbSNP
rs958148890 1665 dbSNP
rs754678513 1670 dbSNP
rs989295752 1676 dbSNP
rs1023976529 1688 dbSNP
rs780665963 1689 dbSNP
rs1429764150 1692 dbSNP
rs1268258670 1695 dbSNP
rs980114159 1696 dbSNP
rs1471057208 1707 dbSNP
rs1361889208 1713 dbSNP
rs1013086864 1714 dbSNP
rs1016502111 1717 dbSNP
rs1254898909 1721 dbSNP
rs1211918495 1722 dbSNP
rs530327267 1726 dbSNP
rs745781556 1731 dbSNP
rs1216590927 1735 dbSNP
rs1207163834 1744 dbSNP
rs1274020421 1745 dbSNP
rs1348961716 1748 dbSNP
rs530778206 1752 dbSNP
rs1334170583 1755 dbSNP
rs182285564 1759 dbSNP
rs146743640 1762 dbSNP
rs748364082 1771 dbSNP
rs1025747243 1785 dbSNP
rs1240760186 1791 dbSNP
rs536937756 1792 dbSNP
rs942199188 1796 dbSNP
rs757672562 1802 dbSNP
rs900767006 1807 dbSNP
rs1358386769 1809 dbSNP
rs1157833057 1810 dbSNP
rs546833238 1817 dbSNP
rs1435198807 1819 dbSNP
rs373214913 1821 dbSNP
rs932223880 1822 dbSNP
rs1189511497 1823 dbSNP
rs964256358 1826 dbSNP
rs187279157 1837 dbSNP
rs1051951869 1844 dbSNP
rs1195573128 1847 dbSNP
rs1445559183 1851 dbSNP
rs1459356608 1852 dbSNP
rs914516421 1855 dbSNP
rs975325201 1855 dbSNP
rs538353121 1856 dbSNP
rs999143050 1859 dbSNP
rs1030716910 1863 dbSNP
rs1432374933 1865 dbSNP
rs1389204668 1867 dbSNP
rs138864615 1868 dbSNP
rs1011175455 1875 dbSNP
rs938740518 1885 dbSNP
rs1400099009 1886 dbSNP
rs1023438877 1889 dbSNP
rs191722702 1891 dbSNP
rs1420304885 1898 dbSNP
rs948927471 1904 dbSNP
rs1037897645 1905 dbSNP
rs1262766486 1910 dbSNP
rs1189041025 1916 dbSNP
rs1486839427 1926 dbSNP
rs1236136377 1929 dbSNP
rs1210013453 1930 dbSNP
rs769917420 1938 dbSNP
rs1308604481 1946 dbSNP
rs1278995830 1948 dbSNP
rs1273028416 1961 dbSNP
rs1215840601 1968 dbSNP
rs1355134247 1973 dbSNP
rs1277150694 1980 dbSNP
rs1357122504 1986 dbSNP
rs1415075372 1986 dbSNP
rs982051798 1987 dbSNP
rs1275175666 1996 dbSNP
rs1447109246 1998 dbSNP
rs1355047738 2003 dbSNP
rs1330917767 2008 dbSNP
rs1464159273 2009 dbSNP
rs993730850 2012 dbSNP
rs1046690838 2035 dbSNP
rs1476342649 2037 dbSNP
rs62304300 2038 dbSNP
rs375358054 2039 dbSNP
rs1007970285 2062 dbSNP
rs1019822622 2062 dbSNP
rs749069924 2069 dbSNP
rs1332141984 2070 dbSNP
rs1233522962 2072 dbSNP
rs868766010 2073 dbSNP
rs1336493277 2076 dbSNP
rs775726571 2086 dbSNP
rs1310238776 2098 dbSNP
rs983415163 2099 dbSNP
rs1373912049 2100 dbSNP
rs996712122 2103 dbSNP
rs554525952 2104 dbSNP
rs1444533494 2114 dbSNP
rs1399625217 2117 dbSNP
rs907951973 2135 dbSNP
rs1256366180 2145 dbSNP
rs1463158132 2151 dbSNP
rs942101507 2154 dbSNP
rs1164470484 2158 dbSNP
rs1021480041 2159 dbSNP
rs1474054893 2169 dbSNP
rs968598920 2183 dbSNP
rs2868076 2184 dbSNP
rs1469213711 2189 dbSNP
rs924598694 2192 dbSNP
rs1156697383 2199 dbSNP
rs1489227823 2203 dbSNP
rs1263341449 2214 dbSNP
rs1387050359 2234 dbSNP
rs868074849 2244 dbSNP
rs992922138 2249 dbSNP
rs916003271 2261 dbSNP
rs1237862193 2262 dbSNP
rs1376081570 2263 dbSNP
rs540523369 2271 dbSNP
rs1052005620 2274 dbSNP
rs1365635535 2281 dbSNP
rs1293139924 2288 dbSNP
rs890699029 2289 dbSNP
rs554054890 2291 dbSNP
rs1347317370 2297 dbSNP
rs920768716 2301 dbSNP
rs184026863 2302 dbSNP
rs935002118 2303 dbSNP
rs1295380225 2304 dbSNP
rs1190257668 2305 dbSNP
rs1486028689 2316 dbSNP
rs190080571 2319 dbSNP
rs1214210007 2320 dbSNP
rs1352845911 2328 dbSNP
rs1238437053 2337 dbSNP
rs768957221 2342 dbSNP
rs1310507282 2344 dbSNP
rs893560640 2345 dbSNP
rs1300760684 2347 dbSNP
rs1382928461 2348 dbSNP
rs1353555076 2353 dbSNP
rs149377476 2357 dbSNP
rs531013234 2360 dbSNP
rs1280131826 2367 dbSNP
rs144715555 2372 dbSNP
rs1212530430 2374 dbSNP
rs899554176 2389 dbSNP
rs1176056775 2391 dbSNP
rs148511432 2392 dbSNP
rs1375425872 2403 dbSNP
rs59640859 2404 dbSNP
rs1179128136 2409 dbSNP
rs1365446882 2411 dbSNP
rs546845615 2415 dbSNP
rs1034940802 2421 dbSNP
rs114182936 2423 dbSNP
rs1191113173 2427 dbSNP
rs1004902804 2429 dbSNP
rs1014895209 2435 dbSNP
rs998773429 2436 dbSNP
rs1342785892 2441 dbSNP
rs1436377401 2442 dbSNP
rs1228278696 2445 dbSNP
rs568553505 2448 dbSNP
rs963695127 2451 dbSNP
rs1320225978 2456 dbSNP
rs973536615 2468 dbSNP
rs1314936945 2481 dbSNP
rs867365957 2490 dbSNP
rs1218307657 2496 dbSNP
rs1356491910 2497 dbSNP
rs1032042205 2499 dbSNP
rs1402136597 2502 dbSNP
rs114387529 2508 dbSNP
rs915932279 2514 dbSNP
rs1425209772 2518 dbSNP
rs953579876 2521 dbSNP
rs970077823 2531 dbSNP
rs1477328095 2538 dbSNP
rs987561952 2539 dbSNP
rs1189374418 2541 dbSNP
rs142750707 2543 dbSNP
rs1326999354 2547 dbSNP
rs1255430002 2549 dbSNP
rs72870296 2556 dbSNP
rs1459129861 2563 dbSNP
rs929515958 2569 dbSNP
rs1053103900 2571 dbSNP
rs537929453 2575 dbSNP
rs554308116 2577 dbSNP
rs866884292 2581 dbSNP
rs946374948 2585 dbSNP
rs1236979518 2586 dbSNP
rs1256217851 2589 dbSNP
rs1338406556 2594 dbSNP
rs1401835623 2601 dbSNP
rs879869446 2605 dbSNP
rs185593627 2611 dbSNP
rs772920730 2612 dbSNP
rs1464722643 2618 dbSNP
rs904911997 2626 dbSNP
rs1391025872 2628 dbSNP
rs1164742487 2629 dbSNP
rs1457846367 2633 dbSNP
rs1192873815 2637 dbSNP
rs1471672122 2639 dbSNP
rs1251076167 2641 dbSNP
rs1041086036 2644 dbSNP
rs1335007137 2647 dbSNP
rs1182424610 2651 dbSNP
rs1003378235 2654 dbSNP
rs932355575 2661 dbSNP
rs1198106601 2662 dbSNP
rs1174101394 2674 dbSNP
rs1469037614 2677 dbSNP
rs1056286161 2680 dbSNP
rs760316971 2687 dbSNP
rs534083631 2689 dbSNP
rs1356074114 2695 dbSNP
rs1261748085 2697 dbSNP
rs1242862911 2698 dbSNP
rs887034811 2702 dbSNP
rs1166200814 2709 dbSNP
rs1306388610 2710 dbSNP
rs776959280 2710 dbSNP
rs779820181 2710 dbSNP
rs377624145 2711 dbSNP
rs762887759 2715 dbSNP
rs1017245353 2719 dbSNP
rs1389745864 2725 dbSNP
rs1159031107 2727 dbSNP
rs1369440959 2728 dbSNP
rs1378430913 2730 dbSNP
rs1177980811 2731 dbSNP
rs1454746491 2732 dbSNP
rs1248586984 2733 dbSNP
rs1019859772 2739 dbSNP
rs1302466437 2744 dbSNP
rs1219270540 2746 dbSNP
rs963449576 2749 dbSNP
rs554068371 2756 dbSNP
rs1029086058 2757 dbSNP
rs1224737309 2759 dbSNP
rs374682244 2760 dbSNP
rs397977661 2760 dbSNP
rs59105562 2760 dbSNP
rs766228660 2762 dbSNP
rs953440810 2771 dbSNP
rs987613596 2772 dbSNP
rs1427275474 2776 dbSNP
rs1170905892 2777 dbSNP
rs1317923509 2778 dbSNP
rs973457504 2779 dbSNP
rs1196174572 2780 dbSNP
rs1212527041 2780 dbSNP
rs766253101 2782 dbSNP
rs956853491 2783 dbSNP
rs34144370 2789 dbSNP
rs1212225876 2796 dbSNP
rs866405651 2796 dbSNP
rs866844868 2797 dbSNP
rs1280059431 2799 dbSNP
rs950901327 2799 dbSNP
rs763126555 2800 dbSNP
rs983997616 2804 dbSNP
rs988453214 2807 dbSNP
rs777206770 2808 dbSNP
rs912081088 2808 dbSNP
rs944913082 2812 dbSNP
rs1426554214 2819 dbSNP
rs577133576 2829 dbSNP
rs1375019151 2833 dbSNP
rs946413205 2835 dbSNP
rs1477004198 2836 dbSNP
rs1466150292 2840 dbSNP
rs1045085789 2841 dbSNP
rs1474033053 2845 dbSNP
rs146281776 2854 dbSNP
rs751110027 2855 dbSNP
rs1042807522 2862 dbSNP
rs939051701 2863 dbSNP
rs1200063242 2867 dbSNP
rs1056212083 2870 dbSNP
rs886964281 2871 dbSNP
rs556308823 2882 dbSNP
rs1228702131 2883 dbSNP
rs1381117380 2884 dbSNP
rs1282338609 2888 dbSNP
rs1384637177 2890 dbSNP
rs1380897517 2893 dbSNP
rs1401121499 2894 dbSNP
rs1333454905 2906 dbSNP
rs1196429382 2911 dbSNP
rs1297193330 2914 dbSNP
rs58776991 2915 dbSNP
rs1038323516 2916 dbSNP
rs1165879908 2921 dbSNP
rs1425894444 2931 dbSNP
rs1412151466 2935 dbSNP
rs898372488 2936 dbSNP
rs994867812 2941 dbSNP
rs1238191686 2942 dbSNP
rs143272317 2942 dbSNP
rs1179992640 2943 dbSNP
rs1336818050 2947 dbSNP
rs1456141714 2948 dbSNP
rs1028922360 2949 dbSNP
rs544691279 2950 dbSNP
rs190599719 2951 dbSNP
rs1484739172 2959 dbSNP
rs181025769 2960 dbSNP
rs994827790 2964 dbSNP
rs1027626788 2968 dbSNP
rs540544199 2969 dbSNP
rs560383818 2974 dbSNP
rs532643623 2975 dbSNP
rs1444697167 2988 dbSNP
rs1376304785 2989 dbSNP
rs1022549877 2996 dbSNP
rs10007784 3001 dbSNP
rs1415713575 3008 dbSNP
rs1019496233 3009 dbSNP
rs77285094 3010 dbSNP
rs1420788410 3014 dbSNP
rs926303770 3015 dbSNP
rs974987263 3031 dbSNP
rs1452075310 3036 dbSNP
rs1157422607 3040 dbSNP
rs10019455 3041 dbSNP
rs1249270899 3049 dbSNP
rs1360742748 3051 dbSNP
rs548220710 3059 dbSNP
rs1244709838 3060 dbSNP
rs755472670 3064 dbSNP
rs534694930 3069 dbSNP
rs1221498030 3079 dbSNP
rs1354282287 3089 dbSNP
rs991946915 3090 dbSNP
rs908282229 3094 dbSNP
rs758997688 3117 dbSNP
rs1237933598 3121 dbSNP
rs1316408750 3130 dbSNP
rs1302077808 3134 dbSNP
rs1310728620 3142 dbSNP
rs939877209 3144 dbSNP
rs1388680608 3146 dbSNP
rs1365781655 3148 dbSNP
rs1356762942 3155 dbSNP
rs1400957732 3157 dbSNP
rs1038570619 3159 dbSNP
rs1306122379 3161 dbSNP
rs898425462 3174 dbSNP
rs1419696328 3187 dbSNP
rs1362650392 3188 dbSNP
rs1176176497 3196 dbSNP
rs185004282 3207 dbSNP
rs1434498235 3220 dbSNP
rs1422661660 3225 dbSNP
rs1240905580 3226 dbSNP
rs932589892 3234 dbSNP
rs1198290736 3251 dbSNP
rs780387780 3275 dbSNP
rs925645934 3281 dbSNP
rs747154791 3283 dbSNP
rs1049614471 3284 dbSNP
rs768600023 3288 dbSNP
rs1464116951 3294 dbSNP
rs760121001 3294 dbSNP
rs889156606 3295 dbSNP
rs1008847485 3297 dbSNP
rs1235550448 3298 dbSNP
rs1282856443 3309 dbSNP
rs1310555829 3309 dbSNP
rs1331009910 3310 dbSNP
rs767570873 3312 dbSNP
rs1342764908 3314 dbSNP
rs1296745012 3317 dbSNP
rs1018996680 3327 dbSNP
rs892508632 3330 dbSNP
rs1302878493 3333 dbSNP
rs1467104228 3337 dbSNP
rs752736710 3339 dbSNP
rs756279523 3344 dbSNP
rs1175248284 3350 dbSNP
rs781538715 3354 dbSNP
rs1182588254 3363 dbSNP
rs1425428586 3363 dbSNP
rs1009754597 3369 dbSNP
rs1022854355 3381 dbSNP
rs1417905313 3383 dbSNP
rs1191264411 3390 dbSNP
rs1427808468 3391 dbSNP
rs1256730071 3401 dbSNP
rs565375170 3408 dbSNP
rs377241503 3411 dbSNP
rs1033928640 3412 dbSNP
rs1262658471 3413 dbSNP
rs960394511 3418 dbSNP
rs1199436286 3419 dbSNP
rs991789761 3420 dbSNP
rs949911082 3426 dbSNP
rs908293681 3429 dbSNP
rs1227199414 3430 dbSNP
rs1341488248 3451 dbSNP
rs79024279 3462 dbSNP
rs547394541 3466 dbSNP
rs1394863088 3470 dbSNP
rs1360547049 3482 dbSNP
rs72870298 3487 dbSNP
rs1297164687 3490 dbSNP
rs188690032 3492 dbSNP
rs1371046485 3507 dbSNP
rs1306458261 3513 dbSNP
rs181254489 3515 dbSNP
rs1309909824 3517 dbSNP
rs1049012055 3524 dbSNP
rs1231809886 3526 dbSNP
rs886448920 3529 dbSNP
rs556129558 3534 dbSNP
rs1179366316 3542 dbSNP
rs1459230483 3542 dbSNP
rs1019067852 3551 dbSNP
rs1195495060 3570 dbSNP
rs1049668674 3573 dbSNP
rs1267676364 3583 dbSNP
rs1243178014 3587 dbSNP
rs996373093 3601 dbSNP
rs959712305 3611 dbSNP
rs1313684904 3612 dbSNP
rs530391692 3615 dbSNP
rs1378531991 3627 dbSNP
rs537960778 3640 dbSNP
rs1326425020 3655 dbSNP
rs1232415375 3659 dbSNP
rs1040331628 3663 dbSNP
rs1180999556 3664 dbSNP
rs979689694 3668 dbSNP
rs1384570918 3672 dbSNP
rs143831419 3672 dbSNP
rs33951934 3672 dbSNP
rs34076658 3672 dbSNP
rs66499257 3672 dbSNP
rs72366244 3672 dbSNP
rs752180944 3672 dbSNP
rs753153960 3672 dbSNP
rs201707777 3676 dbSNP
rs60461169 3681 dbSNP
rs1181358124 3683 dbSNP
rs1239336289 3683 dbSNP
rs925603197 3683 dbSNP
rs867921798 3685 dbSNP
rs1172239472 3686 dbSNP
rs988950363 3688 dbSNP
rs1010092302 3693 dbSNP
rs917034759 3695 dbSNP
rs1287341714 3701 dbSNP
rs1243022262 3702 dbSNP
rs868189452 3704 dbSNP
rs1414735381 3709 dbSNP
rs930526984 3716 dbSNP
rs1331353353 3717 dbSNP
rs1049004906 3720 dbSNP
rs1364788558 3721 dbSNP
rs770893094 3721 dbSNP
rs1298718762 3725 dbSNP
rs1352207571 3731 dbSNP
rs904056895 3741 dbSNP
rs1466742476 3744 dbSNP
rs555010746 3745 dbSNP
rs1002364878 3746 dbSNP
rs1004906795 3757 dbSNP
rs1331875119 3760 dbSNP
rs1478455001 3762 dbSNP
rs1033938494 3767 dbSNP
rs1370240091 3769 dbSNP
rs574517337 3772 dbSNP
rs1197085296 3777 dbSNP
rs960908407 3779 dbSNP
rs1040844142 3783 dbSNP
rs1013275198 3787 dbSNP
rs1487600423 3789 dbSNP
rs1281466378 3791 dbSNP
rs1015705220 3793 dbSNP
rs878954594 3795 dbSNP
rs1345166111 3802 dbSNP
rs961055401 3806 dbSNP
rs1369962506 3818 dbSNP
rs78222164 3826 dbSNP
rs919679047 3827 dbSNP
rs954023090 3828 dbSNP
rs985223111 3835 dbSNP
rs1029134234 3853 dbSNP
rs912500520 3857 dbSNP
rs1401705856 3858 dbSNP
rs1343395477 3859 dbSNP
rs1305783268 3867 dbSNP
rs1200609981 3871 dbSNP
rs943927321 3873 dbSNP
rs1415088254 3885 dbSNP
rs1468473636 3887 dbSNP
rs968242683 3891 dbSNP
rs774132212 3895 dbSNP
rs913913502 3897 dbSNP
rs185271763 3908 dbSNP
rs1248774781 3920 dbSNP
rs577161004 3924 dbSNP
rs1031277385 3931 dbSNP
rs955886072 3932 dbSNP
rs1242016958 3935 dbSNP
rs1442488048 3941 dbSNP
rs945392828 3957 dbSNP
rs988466511 3962 dbSNP
rs1185513715 3970 dbSNP
rs1044231989 3974 dbSNP
rs1478513380 3975 dbSNP
rs1359666295 3977 dbSNP
rs1024409824 3987 dbSNP
rs903901815 4000 dbSNP
rs971083441 4003 dbSNP
rs1002374980 4004 dbSNP
rs1469437644 4014 dbSNP
rs1401344766 4016 dbSNP
rs1173148520 4017 dbSNP
rs6857871 4022 dbSNP
rs896643717 4024 dbSNP
rs562944288 4025 dbSNP
rs1015845537 4033 dbSNP
rs191608057 4047 dbSNP
rs1460515836 4048 dbSNP
rs1258277276 4062 dbSNP
rs150986696 4074 dbSNP
rs1269756860 4079 dbSNP
rs1027154484 4081 dbSNP
rs953776411 4083 dbSNP
rs1358403946 4090 dbSNP
rs1338806639 4091 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucggucgguugagugUCACGUCu 5'
                         ||||||| 
Target 5' -----------cuggAGUGCAGu 3'
 		1 - 12
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucggucGGUUGAGUGUCACGUCu 5'
                |||:  :: ||||||| 
Target 5' ------CCAGGCUGGAGUGCAGu 3'
 		1 - 17
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001201 | 3UTR | CUCUUGUCGCCCAGGCUGGAGUGCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001201 | 3UTR | ACUCUUGUCGCCCAGGCUGGAGUGCAGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001201 | 3UTR | ACUCUUGUCGCCCAGGCUGGAGUGCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001201 | 3UTR | ACUCUUGUCGCCCAGGCUGGAGUGCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_001201 | 3UTR | UUCACUCUUGUCGCCCAGGCUGGAGUGCAGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000282701.2 | 3UTR | CCAGGCUGGAGUGCAGUGGCGUGAUCUCGGCCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000282701.2 | 3UTR | CUGGAGUGCAGUGGCGUGAUCUCGGCCCACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
296 hsa-miR-4793-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT092332 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT131237 ATG2A autophagy related 2A 2 2
MIRT145926 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT206559 SOCS5 suppressor of cytokine signaling 5 2 8
MIRT226455 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT337662 ZNF695 zinc finger protein 695 2 2
MIRT405828 SIX4 SIX homeobox 4 2 2
MIRT455113 RILPL1 Rab interacting lysosomal protein like 1 2 2
MIRT456756 TMEM239 transmembrane protein 239 2 4
MIRT457974 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT458173 LYRM4 LYR motif containing 4 2 4
MIRT458245 SLC9A7 solute carrier family 9 member A7 2 2
MIRT466145 TMEM120B transmembrane protein 120B 2 2
MIRT474981 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT475601 HMGB2 high mobility group box 2 2 4
MIRT480759 BMP3 bone morphogenetic protein 3 2 4
MIRT481156 AVL9 AVL9 cell migration associated 2 2
MIRT482155 AK2 adenylate kinase 2 2 2
MIRT488386 VAV3 vav guanine nucleotide exchange factor 3 2 6
MIRT496575 KIF18B kinesin family member 18B 2 2
MIRT498411 TXNDC16 thioredoxin domain containing 16 2 4
MIRT504547 ZNF417 zinc finger protein 417 2 6
MIRT505417 TCF7L2 transcription factor 7 like 2 2 2
MIRT509349 ALDH9A1 aldehyde dehydrogenase 9 family member A1 2 6
MIRT512164 CD164 CD164 molecule 2 6
MIRT517238 PRIM1 DNA primase subunit 1 2 2
MIRT518671 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT519298 MLH1 mutL homolog 1 2 2
MIRT523662 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT525452 GPATCH2L G-patch domain containing 2 like 2 2
MIRT539847 ZNF766 zinc finger protein 766 2 2
MIRT540076 SSH3 slingshot protein phosphatase 3 2 2
MIRT540320 PIGR polymeric immunoglobulin receptor 2 2
MIRT540548 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT540759 UTP6 UTP6, small subunit processome component 2 2
MIRT541545 HIATL2 major facilitator superfamily domain containing 14C 2 2
MIRT541553 SLC35E1 solute carrier family 35 member E1 2 2
MIRT541666 ATP8B3 ATPase phospholipid transporting 8B3 2 4
MIRT541722 TFDP2 transcription factor Dp-2 2 2
MIRT541800 DUSP28 dual specificity phosphatase 28 2 2
MIRT541816 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT541907 VWA7 von Willebrand factor A domain containing 7 2 2
MIRT542154 UGDH UDP-glucose 6-dehydrogenase 2 2
MIRT542207 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT542233 FUT9 fucosyltransferase 9 2 2
MIRT542320 SERPING1 serpin family G member 1 2 2
MIRT542369 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT542476 APOC3 apolipoprotein C3 2 2
MIRT542641 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT542660 TAF11 TATA-box binding protein associated factor 11 2 2
MIRT542749 PRRG4 proline rich and Gla domain 4 2 4
MIRT542789 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT545442 FGFRL1 fibroblast growth factor receptor like 1 2 2
MIRT546206 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT552270 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552655 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT554134 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT556795 KIAA1958 KIAA1958 2 2
MIRT564762 ZHX3 zinc fingers and homeoboxes 3 2 2
MIRT569428 STX7 syntaxin 7 2 2
MIRT573245 ZBTB46 zinc finger and BTB domain containing 46 2 2
MIRT607390 LANCL3 LanC like 3 2 2
MIRT607430 NOTCH2NL notch 2 N-terminal like 2 2
MIRT607452 ZNF543 zinc finger protein 543 2 2
MIRT607580 TANGO2 transport and golgi organization 2 homolog 2 2
MIRT607748 ANGPT4 angiopoietin 4 2 2
MIRT607907 SPRYD4 SPRY domain containing 4 2 2
MIRT608703 GMPR guanosine monophosphate reductase 2 2
MIRT612127 NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 2 2
MIRT612786 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT616692 LPL lipoprotein lipase 2 2
MIRT617045 ZNF610 zinc finger protein 610 2 2
MIRT617091 ZNF43 zinc finger protein 43 2 2
MIRT617314 MBOAT1 membrane bound O-acyltransferase domain containing 1 2 2
MIRT617355 MELK maternal embryonic leucine zipper kinase 2 2
MIRT617486 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT617579 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT617669 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT617722 TRAPPC2 trafficking protein particle complex 2 2 4
MIRT617893 PTCHD3 patched domain containing 3 2 2
MIRT617982 ZNF234 zinc finger protein 234 2 4
MIRT618434 MYLK3 myosin light chain kinase 3 2 4
MIRT618732 HIST1H2AH histone cluster 1 H2A family member h 2 2
MIRT619045 CASS4 Cas scaffolding protein family member 4 2 2
MIRT619573 ATAT1 alpha tubulin acetyltransferase 1 2 4
MIRT619671 CYP1A2 cytochrome P450 family 1 subfamily A member 2 2 2
MIRT619887 ABHD17B abhydrolase domain containing 17B 2 2
MIRT620519 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 4
MIRT620535 AVPR1A arginine vasopressin receptor 1A 2 2
MIRT620996 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT621304 YIPF4 Yip1 domain family member 4 2 2
MIRT622086 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT622168 SMYD1 SET and MYND domain containing 1 2 2
MIRT622543 PXMP4 peroxisomal membrane protein 4 2 2
MIRT622761 PGM3 phosphoglucomutase 3 2 2
MIRT622885 PDCL3 phosducin like 3 2 4
MIRT623130 NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 2 2
MIRT624840 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT625047 MBD3 methyl-CpG binding domain protein 3 2 2
MIRT625059 ZNF556 zinc finger protein 556 2 2
MIRT625508 PPAPDC1A phospholipid phosphatase 4 2 2
MIRT625573 ANKRD42 ankyrin repeat domain 42 2 2
MIRT626133 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT626327 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT626765 CDC14B cell division cycle 14B 2 2
MIRT626798 CSE1L chromosome segregation 1 like 2 2
MIRT627212 ZC3H12B zinc finger CCCH-type containing 12B 2 2
MIRT627225 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT627256 XKR4 XK related 4 2 2
MIRT628190 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT628466 AHSA2 activator of HSP90 ATPase homolog 2 2 2
MIRT628627 CCT4 chaperonin containing TCP1 subunit 4 2 2
MIRT629040 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT630847 ACACB acetyl-CoA carboxylase beta 2 2
MIRT631721 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT632264 USP1 ubiquitin specific peptidase 1 2 4
MIRT632571 POLQ DNA polymerase theta 2 2
MIRT633992 SLC35E2 solute carrier family 35 member E2 2 2
MIRT635211 ZNF286A zinc finger protein 286A 2 4
MIRT635249 ELOVL6 ELOVL fatty acid elongase 6 2 4
MIRT635261 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT635283 GK5 glycerol kinase 5 (putative) 2 2
MIRT635663 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT636251 SEC63 SEC63 homolog, protein translocation regulator 2 2
MIRT636564 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT636814 TBC1D24 TBC1 domain family member 24 2 2
MIRT637358 ZNF460 zinc finger protein 460 2 2
MIRT637473 DEFB105B defensin beta 105B 2 4
MIRT637505 DEFB105A defensin beta 105A 2 4
MIRT637861 SC5D sterol-C5-desaturase 2 2
MIRT638080 ZNF652 zinc finger protein 652 2 2
MIRT638096 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT638174 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT638201 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT638278 SH2B3 SH2B adaptor protein 3 2 2
MIRT638714 FUT11 fucosyltransferase 11 2 2
MIRT638852 CLMP CXADR like membrane protein 2 2
MIRT639815 TMED8 transmembrane p24 trafficking protein family member 8 2 2
MIRT640879 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT640937 FAM129A family with sequence similarity 129 member A 2 2
MIRT640971 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT641642 GNAZ G protein subunit alpha z 2 2
MIRT641931 SLC25A16 solute carrier family 25 member 16 2 2
MIRT642136 CRY2 cryptochrome circadian clock 2 2 2
MIRT643199 JAK3 Janus kinase 3 2 2
MIRT643256 ZNF566 zinc finger protein 566 2 2
MIRT643378 TRIM16L tripartite motif containing 16 like 2 2
MIRT643683 AMER3 APC membrane recruitment protein 3 2 2
MIRT643728 MCMDC2 minichromosome maintenance domain containing 2 2 2
MIRT643949 CCDC141 coiled-coil domain containing 141 2 2
MIRT644915 SERF1B small EDRK-rich factor 1B 2 2
MIRT645163 NOL9 nucleolar protein 9 2 2
MIRT645547 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT645550 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT645572 TACR2 tachykinin receptor 2 2 2
MIRT646697 SERF1A small EDRK-rich factor 1A 2 2
MIRT647806 FRMD8 FERM domain containing 8 2 2
MIRT647903 CIRH1A UTP4, small subunit processome component 2 2
MIRT648978 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT649907 SLFN12L schlafen family member 12 like 2 2
MIRT650224 SIGLEC9 sialic acid binding Ig like lectin 9 2 4
MIRT651880 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT651935 UBN1 ubinuclein 1 2 2
MIRT652839 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT652994 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT654800 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT655591 OTUD7B OTU deubiquitinase 7B 2 2
MIRT658760 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT659358 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT660717 AMER1 APC membrane recruitment protein 1 2 2
MIRT660737 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT661088 TMEM145 transmembrane protein 145 2 2
MIRT661176 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT662005 ZNF445 zinc finger protein 445 2 2
MIRT662178 KIAA1210 KIAA1210 2 2
MIRT662270 OR51E2 olfactory receptor family 51 subfamily E member 2 2 2
MIRT663046 SLC16A4 solute carrier family 16 member 4 2 2
MIRT663476 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT664039 RPL27A ribosomal protein L27a 2 2
MIRT664096 ZDHHC24 zinc finger DHHC-type containing 24 2 2
MIRT664109 FUT1 fucosyltransferase 1 (H blood group) 2 2
MIRT664317 CD209 CD209 molecule 2 2
MIRT664455 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT664595 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 4
MIRT664694 DBF4 DBF4 zinc finger 2 2
MIRT665162 SF3A1 splicing factor 3a subunit 1 2 2
MIRT665214 RBM22 RNA binding motif protein 22 2 2
MIRT665254 ZNF286B zinc finger protein 286B 2 2
MIRT665268 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT665606 TTC39A tetratricopeptide repeat domain 39A 2 2
MIRT665830 TIMELESS timeless circadian clock 2 2
MIRT666201 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 2 2
MIRT666546 RNF115 ring finger protein 115 2 2
MIRT666602 REEP3 receptor accessory protein 3 2 2
MIRT666862 POU2F3 POU class 2 homeobox 3 2 4
MIRT666886 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT667158 NRXN3 neurexin 3 2 2
MIRT667252 NEK9 NIMA related kinase 9 2 2
MIRT667419 MFSD2A major facilitator superfamily domain containing 2A 2 2
MIRT667434 METTL8 methyltransferase like 8 2 2
MIRT668023 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT668062 GPR75 G protein-coupled receptor 75 2 2
MIRT668070 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT668607 EHD4 EH domain containing 4 2 4
MIRT668694 DNAL1 dynein axonemal light chain 1 2 2
MIRT668782 DAAM1 dishevelled associated activator of morphogenesis 1 2 2
MIRT669037 CHEK1 checkpoint kinase 1 2 2
MIRT669044 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT669156 CCNG1 cyclin G1 2 2
MIRT670090 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT670206 SLC24A4 solute carrier family 24 member 4 2 2
MIRT672488 FUS FUS RNA binding protein 2 2
MIRT673830 SLC11A2 solute carrier family 11 member 2 2 2
MIRT675481 VEGFC vascular endothelial growth factor C 2 2
MIRT675634 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT677913 HIST1H2BN histone cluster 1 H2B family member n 2 2
MIRT678420 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678626 OLFML2A olfactomedin like 2A 2 2
MIRT678791 NUPL2 nucleoporin like 2 2 2
MIRT679561 LIN9 lin-9 DREAM MuvB core complex component 2 2
MIRT680743 CA5B carbonic anhydrase 5B 2 2
MIRT682481 LIX1L limb and CNS expressed 1 like 2 4
MIRT682701 PSMD9 proteasome 26S subunit, non-ATPase 9 2 2
MIRT682759 MDM2 MDM2 proto-oncogene 2 2
MIRT682811 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT682847 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT682896 XIAP X-linked inhibitor of apoptosis 2 2
MIRT682916 FAM73A mitoguardin 1 2 2
MIRT682935 ZNF292 zinc finger protein 292 2 2
MIRT682953 RPL12 ribosomal protein L12 2 2
MIRT682972 NF2 neurofibromin 2 2 2
MIRT683033 SUSD5 sushi domain containing 5 2 2
MIRT683081 A1BG alpha-1-B glycoprotein 2 2
MIRT683105 TIMM10B translocase of inner mitochondrial membrane 10B 2 2
MIRT686640 TMEM184C transmembrane protein 184C 2 2
MIRT687444 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT688401 EMC8 ER membrane protein complex subunit 8 2 2
MIRT688886 C3orf70 chromosome 3 open reading frame 70 2 2
MIRT689148 IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 2 2
MIRT689234 RPS19 ribosomal protein S19 2 2
MIRT689306 C5AR2 complement component 5a receptor 2 2 2
MIRT689364 ZNF101 zinc finger protein 101 2 2
MIRT689498 SCARF1 scavenger receptor class F member 1 2 2
MIRT689655 RBM23 RNA binding motif protein 23 2 2
MIRT689897 SOD2 superoxide dismutase 2 2 2
MIRT690150 PPIL6 peptidylprolyl isomerase like 6 2 2
MIRT690601 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT690805 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT690946 GLG1 golgi glycoprotein 1 2 2
MIRT691388 ATP13A4 ATPase 13A4 2 2
MIRT691408 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT692175 LRRC3C leucine rich repeat containing 3C 2 2
MIRT692235 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT693283 GINM1 glycoprotein integral membrane 1 2 2
MIRT693439 TPGS1 tubulin polyglutamylase complex subunit 1 2 2
MIRT693460 HIST1H2AG histone cluster 1 H2A family member g 2 2
MIRT693768 ZNF383 zinc finger protein 383 2 2
MIRT694018 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694236 ZNF749 zinc finger protein 749 2 2
MIRT694321 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT694347 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT694430 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT695763 WDR35 WD repeat domain 35 2 2
MIRT696167 TIPIN TIMELESS interacting protein 2 2
MIRT696417 DOCK7 dedicator of cytokinesis 7 2 2
MIRT696543 C3 complement C3 2 2
MIRT696998 CCDC80 coiled-coil domain containing 80 2 2
MIRT697232 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT697806 UBXN2A UBX domain protein 2A 2 2
MIRT697944 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT698161 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT698778 STK4 serine/threonine kinase 4 2 2
MIRT700259 RBM12B RNA binding motif protein 12B 2 2
MIRT700970 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT701251 NUP35 nucleoporin 35 2 2
MIRT701607 MYPN myopalladin 2 2
MIRT702457 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT702613 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT702691 IRGQ immunity related GTPase Q 2 2
MIRT702934 HMX3 H6 family homeobox 3 2 2
MIRT702991 HERPUD2 HERPUD family member 2 2 2
MIRT703148 GPR137C G protein-coupled receptor 137C 2 2
MIRT703980 EMC1 ER membrane protein complex subunit 1 2 2
MIRT704569 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2 2
MIRT705065 C4orf32 family with sequence similarity 241 member A 2 2
MIRT705447 ATL2 atlastin GTPase 2 2 2
MIRT705856 AFF3 AF4/FMR2 family member 3 2 2
MIRT705886 ADIPOR2 adiponectin receptor 2 2 2
MIRT714370 HP1BP3 heterochromatin protein 1 binding protein 3 2 2
MIRT715784 PHF12 PHD finger protein 12 2 2
MIRT715864 KIAA0101 PCNA clamp associated factor 2 2
MIRT715947 NUP93 nucleoporin 93 2 2
MIRT716132 THOC5 THO complex 5 2 2
MIRT717084 EBF4 early B-cell factor 4 2 2
MIRT725424 HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2 2
MIRT736091 GREM1 gremlin 1, DAN family BMP antagonist 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4793 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-miR-4793-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4793-3p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4793-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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