miRTarBase - #MIRT481388


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pre-miRNA Information
pre-miRNA hsa-let-7e   
Genomic Coordinates chr19: 51692786 - 51692864
Synonyms MIRNLET7E, hsa-let-7e, let-7e, MIRLET7E
Description Homo sapiens let-7e stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7e-5p
Sequence 8| UGAGGUAGGAGGUUGUAUAGUU |29
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1189776118 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ATG12   
Synonyms APG12, APG12L, FBR93, HAPG12
Description autophagy related 12
Transcript NM_004707   
Expression
Putative miRNA Targets on ATG12
3'UTR of ATG12
(miRNA target sites are highlighted)		 
>ATG12|NM_004707|3'UTR
   1 ACCACAAAGAAAATCAACTTGCTACTACATGAAATGGATTTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTG
  81 GCAAGAGACTTAACAGATGTGATCTATTTAGTATGTGTCTACTCTATGTTTATGCATAAGAAAACATCCATAGCATGAAT
 161 GGACTCAGAAAAATGTGATTTGTATTAATGCACCAGTCATCATAAAAGATGGTCATGATAGTACACCCATTGCTCCTACT
 241 TGTTACTATTATTGCTGCAGATCTGCCTCCAAGGTTGAAAAGGAGACTAAGACTGTATAAACATCTTCATTGTCAGTTCT
 321 CAAAATGACTGAAATTGTTTTCATGGTAAAAGTTAATATACTAAAGGGTTCCTTTTTTTTTAATGTTTACATTTATCTCT
 401 ATGTTTACCTTTTTAGTCACATTGACCTGCTGGCTGAATACCTCAAATAGTCCAGTAGAGGGCAGTCCACCAGGCAGAAA
 481 AGGTTAGGCGTTTTGGTTTCACATCTTTGCTGGGGAATAATAGGGGAAATGGCTGTTTTTGCTAATTTTTAGCTAATATC
 561 TAGCCAGGAGAGCAAGCACATAGGACAGACTGAAAGACTGTAATTTTACACAATACACATGGCTTAATTATTTTATTGGG
 641 ATACAGAAAAATATAAATTCTGGACAAATAAGTCATATACCTGTTTTCAGTCCTAACATTTAAGGATTCTTGAGTCCCAA
 721 TCACATAACTGTGGTGTTACTCTGTCATTTATATGGTGTCAAAAGCACTTGATGAGTAAACCCAGTAGCATCTTTTTGAG
 801 TGTTTCATAATGCATTTTCCAACTTGAAAACAATAATTGAAAAATAGCCTTATTGTATATTTTATGCCATGACTAAAAGT
 881 GCCATTTTTACTGATGCTATTAGACTGATAATTTCTTGAAGTGAAATTTAACCTTTTTTTCTCTTTAGTATTATGTTTAT
 961 AATGCCATATTTTTAGAAAGCATTCCAGATCAGGCATGGTGGCTTACACCTGTAATCCCAGCACTTTGGAAGGCTGAGGT
1041 GTGGGGATTGCGTGAAGCCACAAGTTTGAGACCAGCCTGGTTAGCAAGGCAAGATCCCCAACTCTACAAAAAAATAAAAA
1121 TTAAAAAAAAATTATTAGGCTGCAGAGGCAAGAGGATCCCCTGAGCCCAGAAGTTCAAGGGTATAGTGAGTCGTGATTGT
1201 ACCACTGCATTCCTGCTGAGCAACAGAGTGAGACCCCATCTCAAAAAAGAAAAAAAAAGGCATTCTAGTAAATCGAATGT
1281 AATGTGAATGGAATTTCAAAACAGGATCTAAGATGGTATGTAGTAGAATTCAAAGTAATATCATTTTAAAGTTAAATGAG
1361 TATGGAAAAGGTCTGTTCTCTAGTTTTGTCCAGTTCAGTTTACTGAAGGAATATATTTAATTATATTCATATATTTAACA
1441 AATAAAAATATGTTGAATTTTCGTATTGTTTGCCACTGAGGGTTCAGATGATAGACCTCAAAAAATCGAAAATACTGGTT
1521 GAAATTTGTAGCATCCATTTAGTTATTCTTTTTGACCTAAATAACTTAATAGTTTATTAAATCTAAGGTTAGCTAAATAT
1601 GTAGCTAACCTTATTTGTTTTCTTTCCTAACAACTCTGAAGAATACATAGGACTTTGCACTTTTTTTTTTTTTTTTTTTT
1681 TTTAAAGAGACAGCGTTTCGGTCTTGTTGCCCAGGCTGGACTGTAATGGCACAATCTTGGCTCATTGCAACCTCTACCTC
1761 CCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCTGCCACCACACCCGCCTAATTTT
1841 TTGTTATTTTTAGTGGAGACAGGGTTTTACCATTTTGGCCAGGCTGGTCTCAAACTCCTGACTGACCTCAGGTGATCCAC
1921 CCGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCGTGCCGGGCCTGGACTTTGTACTTTTTCAAATCAT
2001 ATTTAATTATTTCTTGATCTTTACTCAAAGAATTATTCTGCGCTAAATTTGCAACATTAAACAATAATTAAGCCTGGATC
2081 CGATAAGTTATTGGGTGACTAGAACCTACAACACAATTTATTTTTAATTTAAACTCTCAAGTCTGATTAAACTTGGGGGA
2161 AAAACTGAACATTCAGGTGATATTTTAAATTTTCTTTGTGACTAAATAGATGTCATTAATATCATGCTTCATCTTACTGT
2241 GCATAGATGACCCATGGCACACAAAGTATATGTATAATATTGCAATATTGTACTTCCATCTTTAAAAGTATGCCAAAGAC
2321 TTCATAATGAATTCACCATATTTAAGGAATAAGGCAAATTAATGTTTATCCGAAATCAAAATGAGATTGGATAATTCCTG
2401 GAATCTGATTTCTGTAAGTTTCAGTCCTAAAGGGACCTTAAATATCTACTAGAACGAAGTACAGTGTATTTCTCAGATTA
2481 CATGACATTAGTCAACCAATTTAGTTGTAACACAAAGTGAGAAAGCCTTAGGTGTTGAAGGAGTGTGAAAATAAAAATCT
2561 CTTTTCATGCAGTTTCTGCTTCATTTTCCAAGGATTATAATATGCTGAGTAAACTTTTGGCACTAAGGAAGCCAGCTACA
2641 GGCCACGTAATGAAAACTATTCAGAAAACAGTTCAGCAAATACTACTATTTGAATACAGTTCAAATCGTATTTATATAAA
2721 TACTCTGCCTACATTATTTAACCCAAACTGGATTATTCACCATTCTTTGAAGATGCCTTGTGTTTTCTGTTATCTACTTC
2801 TGCTCGTGCAGTTTACTTACACCTTCACCCTTTCAAATCCTAACTCTTCTTCAAGGCCTGATTCAGATTTTAACTTTTTA
2881 AAGGCTATCTGAATCATTCAAGGAGAAGATACCCTTTCTCTCATAAAAACACTTAGAGCAAACTACCACTATTAAATCAC
2961 TTATTGCATACTGCCTCAGAGCCATGTGTCCAGTTATTCTGGTTTTTATCTGGTACCCACACACACATAATACTTAGTAC
3041 ATTTCCTTATATGTAAATAATTAGTAATGTAACACATCGAGTGAATGAAATTGTGATTAGCAAAGTATGACAGCTAAAAA
3121 CAAAGGAAATTTTGTATAGTTTAAGTTTTTGTACAGCAGAAGGTAATGGAAAATATTTGCAACATATGACAGTGTTTTTA
3201 ATGTCTTAAGTATATGAAGAATTTGTTTCAATTGGTAAGAAAAGACCAACTGAAAAATAGGCAAAACATACCAAATTTCG
3281 ATTCACAAAAAGATACAAATGGCCAACAAAACATGAAACACCTTGAACCCCATTGGTTACAAAAAATACAAATAAAAACA
3361 ATGCTGACTGACAATAAAAATAATGTACATCTTGCTATTAGCAGAGTTGTGGGGAAATCCTGTCATATTTTGGTGAATAG
3441 AATATGAGTTGGTATATCACTTTTAGGGGGCCATTTGGCAATATCAAAAACCTTGAAACGTAAGTATAAACTTCAGTTTG
3521 TTCGTATAACCTGTCATTCACATATTGAGTGCCTACTATGTCCTAAATATTGGAATAACACTAATAAAGCTCATAAGAGA
3601 CTAATAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uugauAUGUUGGAGGAUGGAGu 5'
               |:|||||| ||||||| 
Target 5' ctcatTGCAACCT-CTACCTCc 3'
 1741 - 1761 168.00 -19.80
2 
miRNA  3' uugauaugUUGGAGGAUGGAGu 5'
                  | :|||||:|||| 
Target 5' ttcaagtgATTCTCCTGCCTCa 3'
 1766 - 1787 142.00 -21.00
3 
miRNA  3' uuGAUAUGUUGGAGGAUGGAGu 5'
            || ||: :| | ||:|||| 
Target 5' caCT-TATTGCATACTGCCTCa 3'
 2958 - 2978 139.00 -14.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26438649 11 COSMIC
COSN30482964 21 COSMIC
COSN26967095 27 COSMIC
COSN26643998 46 COSMIC
COSN30513254 56 COSMIC
COSN31549497 69 COSMIC
COSN31586844 75 COSMIC
COSN28688947 116 COSMIC
COSN30134431 116 COSMIC
COSN10042093 148 COSMIC
COSN31560191 190 COSMIC
COSN2061927 711 COSMIC
COSN10042092 976 COSMIC
COSN20091236 1404 COSMIC
COSN22544809 1829 COSMIC
COSN10042091 1998 COSMIC
COSN23418775 2407 COSMIC
COSN31830467 2452 COSMIC
COSN8200897 3150 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs989370630 2 dbSNP
rs780304584 4 dbSNP
rs1030826296 8 dbSNP
rs1462530351 9 dbSNP
rs1473761532 13 dbSNP
rs769950972 13 dbSNP
rs746126818 17 dbSNP
rs1307111946 18 dbSNP
rs954983970 21 dbSNP
rs373241953 22 dbSNP
rs369603820 24 dbSNP
rs1160841523 29 dbSNP
rs752676898 30 dbSNP
rs778773750 34 dbSNP
rs1453982318 36 dbSNP
rs1408809819 42 dbSNP
rs1296786066 44 dbSNP
rs754487022 45 dbSNP
rs373112526 46 dbSNP
rs1171994389 47 dbSNP
rs759863605 50 dbSNP
rs183270932 64 dbSNP
rs903140763 66 dbSNP
rs1231562977 69 dbSNP
rs1012755106 76 dbSNP
rs536050702 80 dbSNP
rs1222966368 85 dbSNP
rs1026962147 97 dbSNP
rs1306399266 105 dbSNP
rs769445513 106 dbSNP
rs1256723631 109 dbSNP
rs192452688 111 dbSNP
rs1037155606 114 dbSNP
rs1183746285 119 dbSNP
rs115231681 126 dbSNP
rs1252061851 126 dbSNP
rs1302446044 131 dbSNP
rs1447176475 136 dbSNP
rs1416519025 153 dbSNP
rs891294259 154 dbSNP
rs1375393308 159 dbSNP
rs533822467 184 dbSNP
rs1296665540 187 dbSNP
rs931739782 191 dbSNP
rs866375535 193 dbSNP
rs878992972 194 dbSNP
rs372574699 195 dbSNP
rs1346778919 196 dbSNP
rs571252520 202 dbSNP
rs908119856 203 dbSNP
rs1461599072 204 dbSNP
rs114238378 207 dbSNP
rs933656108 213 dbSNP
rs989174213 214 dbSNP
rs746796327 216 dbSNP
rs923891852 217 dbSNP
rs1312993579 221 dbSNP
rs975056233 224 dbSNP
rs779895487 226 dbSNP
rs1194706175 229 dbSNP
rs963816373 229 dbSNP
rs1394973632 233 dbSNP
rs1433479178 235 dbSNP
rs1394944811 236 dbSNP
rs925684870 238 dbSNP
rs1397232795 242 dbSNP
rs1179656762 246 dbSNP
rs1409456564 248 dbSNP
rs978622047 261 dbSNP
rs1441924174 267 dbSNP
rs978415960 269 dbSNP
rs1020214110 273 dbSNP
rs1368677942 278 dbSNP
rs1230442447 279 dbSNP
rs970554032 285 dbSNP
rs1338133006 289 dbSNP
rs1256104754 292 dbSNP
rs959932419 303 dbSNP
rs796776205 304 dbSNP
rs990895970 315 dbSNP
rs1214704493 316 dbSNP
rs1001483941 323 dbSNP
rs537817403 330 dbSNP
rs761771630 332 dbSNP
rs1195872091 344 dbSNP
rs867405101 353 dbSNP
rs1475099589 357 dbSNP
rs758315418 359 dbSNP
rs1166280556 360 dbSNP
rs1396925100 361 dbSNP
rs1026932695 370 dbSNP
rs866996403 372 dbSNP
rs568861348 379 dbSNP
rs1038150005 382 dbSNP
rs536940080 382 dbSNP
rs1240692110 383 dbSNP
rs1337297097 385 dbSNP
rs1305194519 389 dbSNP
rs995502041 391 dbSNP
rs897412171 393 dbSNP
rs549060335 398 dbSNP
rs186672611 401 dbSNP
rs1491360838 402 dbSNP
rs778297649 403 dbSNP
rs1285511805 408 dbSNP
rs1432869215 416 dbSNP
rs751181202 418 dbSNP
rs1232241527 421 dbSNP
rs1008907130 423 dbSNP
rs1270890072 442 dbSNP
rs1467386977 446 dbSNP
rs891269049 460 dbSNP
rs1207288024 463 dbSNP
rs922164889 468 dbSNP
rs1039421942 471 dbSNP
rs1050369651 483 dbSNP
rs561465423 488 dbSNP
rs548139647 489 dbSNP
rs942304732 490 dbSNP
rs900286929 498 dbSNP
rs1164426381 501 dbSNP
rs182137915 503 dbSNP
rs1455131819 508 dbSNP
rs1289270216 509 dbSNP
rs565540834 517 dbSNP
rs936281372 519 dbSNP
rs923610415 528 dbSNP
rs1418175470 538 dbSNP
rs749401199 539 dbSNP
rs566276006 541 dbSNP
rs913082417 542 dbSNP
rs1241587049 544 dbSNP
rs191608381 558 dbSNP
rs576343311 559 dbSNP
rs1256792825 563 dbSNP
rs917740201 565 dbSNP
rs1486010204 572 dbSNP
rs991091353 576 dbSNP
rs1187372420 580 dbSNP
rs959983800 584 dbSNP
rs1217220920 586 dbSNP
rs1421173829 589 dbSNP
rs1159545859 591 dbSNP
rs1451365820 591 dbSNP
rs544547116 591 dbSNP
rs1175394758 594 dbSNP
rs143487813 601 dbSNP
rs1027066991 602 dbSNP
rs1402361521 602 dbSNP
rs1375071637 610 dbSNP
rs77784086 615 dbSNP
rs1322557227 628 dbSNP
rs1016359106 636 dbSNP
rs374376128 641 dbSNP
rs573528837 655 dbSNP
rs1016027842 663 dbSNP
rs1349284755 669 dbSNP
rs1210246009 675 dbSNP
rs752469768 678 dbSNP
rs553532136 683 dbSNP
rs1051962326 697 dbSNP
rs955841446 698 dbSNP
rs112893491 700 dbSNP
rs370060633 705 dbSNP
rs1395583175 709 dbSNP
rs1434101268 718 dbSNP
rs1039270191 720 dbSNP
rs893310745 724 dbSNP
rs115582210 725 dbSNP
rs1297193749 728 dbSNP
rs1370785956 734 dbSNP
rs904163048 736 dbSNP
rs1306175429 737 dbSNP
rs1372344872 753 dbSNP
rs1234125221 754 dbSNP
rs1299829535 756 dbSNP
rs1384449083 758 dbSNP
rs1309293668 760 dbSNP
rs1205338057 762 dbSNP
rs1250948400 765 dbSNP
rs1000631910 767 dbSNP
rs35614583 772 dbSNP
rs1383372017 777 dbSNP
rs1058600 788 dbSNP
rs1191623534 795 dbSNP
rs1421592662 796 dbSNP
rs1042470400 797 dbSNP
rs1428567840 799 dbSNP
rs1169179144 801 dbSNP
rs1458674597 802 dbSNP
rs945817432 805 dbSNP
rs1326183757 807 dbSNP
rs1368754692 811 dbSNP
rs537454815 812 dbSNP
rs1440671927 819 dbSNP
rs1292242914 823 dbSNP
rs1364761297 826 dbSNP
rs1215210429 831 dbSNP
rs1473968165 833 dbSNP
rs917863507 839 dbSNP
rs1193708078 845 dbSNP
rs766831495 845 dbSNP
rs992661409 848 dbSNP
rs1274072800 853 dbSNP
rs185269788 855 dbSNP
rs759471103 859 dbSNP
rs938480503 865 dbSNP
rs763455553 875 dbSNP
rs1448673096 879 dbSNP
rs1486191654 891 dbSNP
rs927219332 893 dbSNP
rs937808196 898 dbSNP
rs919772159 899 dbSNP
rs1416694824 919 dbSNP
rs1259489684 932 dbSNP
rs1204403415 941 dbSNP
rs974103774 943 dbSNP
rs961463150 946 dbSNP
rs1275332562 947 dbSNP
rs1231647541 948 dbSNP
rs1334388141 950 dbSNP
rs141085212 952 dbSNP
rs145076153 964 dbSNP
rs1347462850 979 dbSNP
rs1432189738 980 dbSNP
rs1288814435 989 dbSNP
rs1338440349 990 dbSNP
rs987240012 991 dbSNP
rs955647686 1007 dbSNP
rs1016701557 1014 dbSNP
rs983458217 1015 dbSNP
rs1286155608 1016 dbSNP
rs1370343662 1017 dbSNP
rs10463672 1018 dbSNP
rs1028952732 1024 dbSNP
rs1486340288 1027 dbSNP
rs1030417748 1029 dbSNP
rs1256330303 1033 dbSNP
rs9326975 1035 dbSNP
rs900644934 1038 dbSNP
rs1410550639 1039 dbSNP
rs1401658695 1045 dbSNP
rs1416651354 1048 dbSNP
rs1359236966 1050 dbSNP
rs957498133 1051 dbSNP
rs1017887927 1052 dbSNP
rs1355044389 1055 dbSNP
rs1476105450 1057 dbSNP
rs1371323076 1058 dbSNP
rs1446016419 1058 dbSNP
rs1281493208 1059 dbSNP
rs1373737100 1060 dbSNP
rs1192353929 1062 dbSNP
rs1283773529 1076 dbSNP
rs1350013354 1083 dbSNP
rs1210974432 1086 dbSNP
rs531696621 1093 dbSNP
rs1440214736 1095 dbSNP
rs1254686488 1101 dbSNP
rs1000599299 1108 dbSNP
rs1183454558 1116 dbSNP
rs1211535631 1120 dbSNP
rs1468212929 1128 dbSNP
rs1470702945 1129 dbSNP
rs181258336 1131 dbSNP
rs1197699730 1132 dbSNP
rs1042050490 1133 dbSNP
rs1174829833 1140 dbSNP
rs1374856033 1144 dbSNP
rs1412867413 1147 dbSNP
rs945730794 1149 dbSNP
rs891542925 1156 dbSNP
rs1441171053 1157 dbSNP
rs1234565844 1163 dbSNP
rs1373083797 1165 dbSNP
rs1373780809 1168 dbSNP
rs1302593022 1169 dbSNP
rs1342214633 1179 dbSNP
rs1197083913 1190 dbSNP
rs1013710742 1192 dbSNP
rs896157276 1193 dbSNP
rs188013466 1195 dbSNP
rs938529587 1199 dbSNP
rs927103295 1211 dbSNP
rs1194761438 1215 dbSNP
rs937947013 1217 dbSNP
rs1377578322 1218 dbSNP
rs919741154 1219 dbSNP
rs377339961 1223 dbSNP
rs1038194001 1229 dbSNP
rs1169766696 1232 dbSNP
rs1409669413 1238 dbSNP
rs940098506 1238 dbSNP
rs941970684 1238 dbSNP
rs908659047 1240 dbSNP
rs1411201601 1242 dbSNP
rs1393649302 1243 dbSNP
rs1166762433 1247 dbSNP
rs1325087998 1248 dbSNP
rs11558586 1249 dbSNP
rs1329307708 1249 dbSNP
rs1270324814 1250 dbSNP
rs983896170 1252 dbSNP
rs950707103 1255 dbSNP
rs1191523200 1258 dbSNP
rs1030434340 1259 dbSNP
rs1214762385 1259 dbSNP
rs1267236283 1259 dbSNP
rs1453573887 1260 dbSNP
rs185205965 1267 dbSNP
rs955521362 1268 dbSNP
rs1477540790 1274 dbSNP
rs563141673 1275 dbSNP
rs1420326174 1284 dbSNP
rs1461738568 1288 dbSNP
rs1272418397 1289 dbSNP
rs975640338 1293 dbSNP
rs1162500394 1294 dbSNP
rs1388467893 1299 dbSNP
rs531654169 1302 dbSNP
rs1201062416 1310 dbSNP
rs904144838 1312 dbSNP
rs761297362 1313 dbSNP
rs1397615662 1315 dbSNP
rs1294720212 1318 dbSNP
rs776312820 1331 dbSNP
rs1278806605 1335 dbSNP
rs1265286313 1338 dbSNP
rs977621572 1341 dbSNP
rs1207344954 1343 dbSNP
rs1378080408 1345 dbSNP
rs1279811211 1370 dbSNP
rs1487978158 1371 dbSNP
rs966486542 1373 dbSNP
rs1021169475 1375 dbSNP
rs1021085753 1378 dbSNP
rs1443959935 1380 dbSNP
rs866083681 1386 dbSNP
rs1327617015 1388 dbSNP
rs896115015 1393 dbSNP
rs1366427710 1396 dbSNP
rs891432155 1400 dbSNP
rs1455180607 1401 dbSNP
rs1159025185 1403 dbSNP
rs1359878590 1410 dbSNP
rs1056825810 1411 dbSNP
rs1314245796 1420 dbSNP
rs1355684594 1425 dbSNP
rs1033327919 1431 dbSNP
rs1377275478 1447 dbSNP
rs1002599692 1451 dbSNP
rs1241658167 1453 dbSNP
rs1433924896 1454 dbSNP
rs905606540 1455 dbSNP
rs1353700156 1456 dbSNP
rs1408409586 1459 dbSNP
rs1044654448 1462 dbSNP
rs941870184 1463 dbSNP
rs1420631654 1467 dbSNP
rs1468819201 1469 dbSNP
rs1232459937 1471 dbSNP
rs182004521 1474 dbSNP
rs1047612920 1475 dbSNP
rs1437813965 1476 dbSNP
rs1175455995 1478 dbSNP
rs1375453012 1479 dbSNP
rs1465138381 1480 dbSNP
rs898450246 1483 dbSNP
rs929317535 1486 dbSNP
rs768321991 1488 dbSNP
rs1310520999 1499 dbSNP
rs976068997 1507 dbSNP
rs964826775 1508 dbSNP
rs910639452 1513 dbSNP
rs980013440 1515 dbSNP
rs1210756987 1516 dbSNP
rs201848657 1522 dbSNP
rs397884197 1525 dbSNP
rs5870670 1525 dbSNP
rs149885972 1531 dbSNP
rs886953323 1533 dbSNP
rs1051587215 1535 dbSNP
rs573808242 1541 dbSNP
rs569726913 1543 dbSNP
rs1195386041 1546 dbSNP
rs1348102811 1548 dbSNP
rs1278588338 1551 dbSNP
rs1432074385 1557 dbSNP
rs1173398668 1561 dbSNP
rs960923980 1567 dbSNP
rs921246325 1568 dbSNP
rs139034616 1573 dbSNP
rs1002485350 1575 dbSNP
rs1328488639 1576 dbSNP
rs1368964288 1579 dbSNP
rs868782601 1581 dbSNP
rs1311040298 1583 dbSNP
rs1299359665 1585 dbSNP
rs35179959 1588 dbSNP
rs1228344730 1597 dbSNP
rs772559413 1600 dbSNP
rs1315783317 1603 dbSNP
rs557809600 1614 dbSNP
rs1215389341 1617 dbSNP
rs1253518873 1619 dbSNP
rs1320061078 1621 dbSNP
rs1189409268 1624 dbSNP
rs1175580693 1625 dbSNP
rs977674085 1626 dbSNP
rs1169452351 1631 dbSNP
rs1006473845 1637 dbSNP
rs967919272 1642 dbSNP
rs887595133 1647 dbSNP
rs544494753 1651 dbSNP
rs1407603571 1653 dbSNP
rs35903246 1654 dbSNP
rs992297535 1655 dbSNP
rs1488549444 1656 dbSNP
rs1400716278 1657 dbSNP
rs1476250785 1658 dbSNP
rs933271085 1659 dbSNP
rs1187245182 1660 dbSNP
rs144023498 1661 dbSNP
rs929238509 1661 dbSNP
rs1486484949 1663 dbSNP
rs1320891427 1664 dbSNP
rs1244266378 1665 dbSNP
rs1214173339 1667 dbSNP
rs1446775880 1668 dbSNP
rs1283184080 1682 dbSNP
rs1233494793 1683 dbSNP
rs1192349203 1684 dbSNP
rs1260585239 1684 dbSNP
rs1347518915 1684 dbSNP
rs1476016817 1684 dbSNP
rs1485895365 1684 dbSNP
rs35337050 1684 dbSNP
rs397882913 1684 dbSNP
rs751451522 1684 dbSNP
rs775644423 1684 dbSNP
rs1336445166 1685 dbSNP
rs1420354202 1688 dbSNP
rs1290927475 1694 dbSNP
rs923176838 1695 dbSNP
rs575342119 1699 dbSNP
rs113359213 1700 dbSNP
rs1040439870 1706 dbSNP
rs943313194 1707 dbSNP
rs1001863424 1709 dbSNP
rs1215241335 1711 dbSNP
rs190817949 1729 dbSNP
rs535406830 1732 dbSNP
rs1283188477 1733 dbSNP
rs1362580069 1734 dbSNP
rs898168789 1736 dbSNP
rs1968365 1738 dbSNP
rs979514765 1743 dbSNP
rs1004146185 1744 dbSNP
rs886917786 1750 dbSNP
rs1344352381 1751 dbSNP
rs968638276 1752 dbSNP
rs1326288049 1754 dbSNP
rs552987705 1756 dbSNP
rs1358655648 1757 dbSNP
rs934056017 1762 dbSNP
rs899953038 1763 dbSNP
rs534167497 1773 dbSNP
rs1281128565 1777 dbSNP
rs745734131 1780 dbSNP
rs372345229 1788 dbSNP
rs925952482 1791 dbSNP
rs144265366 1795 dbSNP
rs140926682 1830 dbSNP
rs569171511 1831 dbSNP
rs770058716 1833 dbSNP
rs1208449984 1837 dbSNP
rs1254058700 1846 dbSNP
rs1005994020 1847 dbSNP
rs548985095 1854 dbSNP
rs1215891664 1856 dbSNP
rs1469546309 1861 dbSNP
rs185138265 1868 dbSNP
rs1379051603 1877 dbSNP
rs960732167 1880 dbSNP
rs1026181902 1887 dbSNP
rs1173300696 1888 dbSNP
rs993329485 1889 dbSNP
rs1412925104 1891 dbSNP
rs1307540125 1894 dbSNP
rs1331136150 1900 dbSNP
rs1400708384 1902 dbSNP
rs749753101 1908 dbSNP
rs980495495 1910 dbSNP
rs1329200096 1914 dbSNP
rs1040283739 1916 dbSNP
rs1212766292 1922 dbSNP
rs748218666 1923 dbSNP
rs193031829 1926 dbSNP
rs147292218 1937 dbSNP
rs951358765 1941 dbSNP
rs913965761 1944 dbSNP
rs1198471456 1946 dbSNP
rs867035977 1947 dbSNP
rs189086901 1949 dbSNP
rs1453904064 1954 dbSNP
rs998069895 1965 dbSNP
rs755190821 1966 dbSNP
rs144115997 1967 dbSNP
rs184054463 1968 dbSNP
rs969594673 1970 dbSNP
rs148175323 1971 dbSNP
rs1464886789 1974 dbSNP
rs40094 1975 dbSNP
rs867293102 1999 dbSNP
rs1396587142 2001 dbSNP
rs1387208408 2002 dbSNP
rs1322823105 2009 dbSNP
rs1328811557 2017 dbSNP
rs1432337695 2030 dbSNP
rs576243586 2030 dbSNP
rs946280547 2036 dbSNP
rs1218406576 2039 dbSNP
rs780394833 2041 dbSNP
rs1057504884 2042 dbSNP
rs186742543 2054 dbSNP
rs1289830441 2057 dbSNP
rs1480731098 2059 dbSNP
rs927477975 2063 dbSNP
rs889015892 2064 dbSNP
rs1201748923 2067 dbSNP
rs980464446 2073 dbSNP
rs1043766245 2080 dbSNP
rs572837991 2081 dbSNP
rs909539282 2083 dbSNP
rs1369918020 2090 dbSNP
rs758754672 2090 dbSNP
rs951373081 2093 dbSNP
rs182407719 2100 dbSNP
rs998520700 2101 dbSNP
rs1401927740 2110 dbSNP
rs1298350598 2112 dbSNP
rs963845177 2116 dbSNP
rs1397688207 2119 dbSNP
rs10052079 2121 dbSNP
rs1000265343 2134 dbSNP
rs571781518 2138 dbSNP
rs1342595673 2140 dbSNP
rs904639367 2141 dbSNP
rs558346175 2146 dbSNP
rs910123617 2152 dbSNP
rs984477849 2158 dbSNP
rs1218879362 2160 dbSNP
rs1441483152 2164 dbSNP
rs144827016 2165 dbSNP
rs1026084610 2168 dbSNP
rs971785692 2169 dbSNP
rs1258585744 2173 dbSNP
rs193095672 2177 dbSNP
rs1366644044 2183 dbSNP
rs188886361 2183 dbSNP
rs76687485 2195 dbSNP
rs1419316251 2198 dbSNP
rs953358656 2203 dbSNP
rs879805414 2209 dbSNP
rs1417356104 2212 dbSNP
rs753282550 2212 dbSNP
rs1304191209 2213 dbSNP
rs1252137964 2214 dbSNP
rs1402529381 2219 dbSNP
rs1175037609 2220 dbSNP
rs1482433187 2221 dbSNP
rs1339079877 2222 dbSNP
rs1242873136 2225 dbSNP
rs759616847 2225 dbSNP
rs1353040771 2226 dbSNP
rs937613156 2231 dbSNP
rs1212898467 2232 dbSNP
rs1257973626 2234 dbSNP
rs746181134 2241 dbSNP
rs1037863244 2243 dbSNP
rs1253750070 2245 dbSNP
rs1345595613 2257 dbSNP
rs1255216883 2264 dbSNP
rs1458944193 2266 dbSNP
rs753348291 2266 dbSNP
rs941106947 2268 dbSNP
rs1379657288 2270 dbSNP
rs879738036 2272 dbSNP
rs1437252159 2277 dbSNP
rs1318965680 2279 dbSNP
rs1305131583 2282 dbSNP
rs1227929947 2285 dbSNP
rs183879013 2290 dbSNP
rs1314781226 2292 dbSNP
rs1010913845 2293 dbSNP
rs982942420 2296 dbSNP
rs1404299382 2301 dbSNP
rs929625919 2316 dbSNP
rs1449501647 2320 dbSNP
rs922275491 2321 dbSNP
rs868216705 2323 dbSNP
rs892433370 2328 dbSNP
rs1389742844 2331 dbSNP
rs1312864374 2333 dbSNP
rs976675720 2342 dbSNP
rs1232747274 2343 dbSNP
rs1254518928 2350 dbSNP
rs1289823405 2353 dbSNP
rs940090781 2370 dbSNP
rs763675838 2371 dbSNP
rs555183664 2372 dbSNP
rs546808463 2375 dbSNP
rs1456438944 2376 dbSNP
rs1192854347 2390 dbSNP
rs1267365160 2407 dbSNP
rs1432112974 2414 dbSNP
rs1196253695 2419 dbSNP
rs906619956 2420 dbSNP
rs1467503391 2421 dbSNP
rs978628932 2437 dbSNP
rs968541715 2442 dbSNP
rs1472002874 2448 dbSNP
rs550897566 2454 dbSNP
rs1020332051 2455 dbSNP
rs879073063 2456 dbSNP
rs1386324640 2459 dbSNP
rs1281587233 2463 dbSNP
rs1049095183 2468 dbSNP
rs1484658461 2474 dbSNP
rs775153335 2475 dbSNP
rs17477896 2482 dbSNP
rs918951851 2497 dbSNP
rs544442100 2499 dbSNP
rs1487853479 2502 dbSNP
rs1189012002 2503 dbSNP
rs1264879836 2506 dbSNP
rs1477906884 2510 dbSNP
rs1192502524 2511 dbSNP
rs1423298381 2514 dbSNP
rs1036124210 2517 dbSNP
rs34310069 2530 dbSNP
rs1427141720 2532 dbSNP
rs965817806 2537 dbSNP
rs759393254 2540 dbSNP
rs1001727863 2541 dbSNP
rs1457459073 2541 dbSNP
rs375346636 2552 dbSNP
rs985983551 2552 dbSNP
rs953298633 2561 dbSNP
rs906159955 2562 dbSNP
rs58119889 2567 dbSNP
rs561974034 2569 dbSNP
rs1335659935 2572 dbSNP
rs191712146 2575 dbSNP
rs886615205 2580 dbSNP
rs1231454588 2583 dbSNP
rs1003498242 2589 dbSNP
rs1488345440 2600 dbSNP
rs1215392122 2603 dbSNP
rs1260644019 2606 dbSNP
rs1485085229 2614 dbSNP
rs1184020319 2616 dbSNP
rs1046784018 2617 dbSNP
rs770964126 2618 dbSNP
rs542140407 2620 dbSNP
rs906630027 2624 dbSNP
rs572903413 2630 dbSNP
rs929735862 2632 dbSNP
rs1420415499 2641 dbSNP
rs776683577 2644 dbSNP
rs1045095039 2646 dbSNP
rs1449951103 2647 dbSNP
rs559284860 2659 dbSNP
rs1320262850 2661 dbSNP
rs1378192486 2662 dbSNP
rs1243620803 2665 dbSNP
rs1012431240 2670 dbSNP
rs976445869 2673 dbSNP
rs1048539454 2676 dbSNP
rs930247640 2677 dbSNP
rs566281689 2683 dbSNP
rs1166473253 2684 dbSNP
rs918832414 2685 dbSNP
rs1036067089 2686 dbSNP
rs942588835 2687 dbSNP
rs1261635678 2688 dbSNP
rs1182239291 2689 dbSNP
rs1461162812 2689 dbSNP
rs1367883084 2697 dbSNP
rs944313993 2699 dbSNP
rs911100812 2708 dbSNP
rs149362454 2714 dbSNP
rs185917193 2716 dbSNP
rs1430129395 2718 dbSNP
rs1177086959 2741 dbSNP
rs138711999 2748 dbSNP
rs182474415 2750 dbSNP
rs1333260605 2762 dbSNP
rs1377630662 2768 dbSNP
rs1020554144 2770 dbSNP
rs1207813694 2772 dbSNP
rs1445397174 2775 dbSNP
rs988892252 2776 dbSNP
rs575422583 2784 dbSNP
rs1277194466 2785 dbSNP
rs748273602 2787 dbSNP
rs554132609 2789 dbSNP
rs1323234437 2793 dbSNP
rs190210896 2793 dbSNP
rs989320431 2794 dbSNP
rs1260532992 2797 dbSNP
rs1355699289 2800 dbSNP
rs143381882 2802 dbSNP
rs374655515 2802 dbSNP
rs1230302656 2805 dbSNP
rs1181743418 2806 dbSNP
rs1231202042 2808 dbSNP
rs1479067947 2815 dbSNP
rs1191961739 2820 dbSNP
rs1424789737 2825 dbSNP
rs1030838142 2829 dbSNP
rs1172640121 2834 dbSNP
rs150221280 2844 dbSNP
rs1464982042 2847 dbSNP
rs1001529903 2849 dbSNP
rs1326796718 2850 dbSNP
rs1332278015 2855 dbSNP
rs1297340657 2858 dbSNP
rs1436616135 2860 dbSNP
rs115936962 2863 dbSNP
rs747919131 2866 dbSNP
rs1023741181 2867 dbSNP
rs1260335234 2871 dbSNP
rs1012771183 2872 dbSNP
rs3862064 2879 dbSNP
rs1271554149 2884 dbSNP
rs1006443158 2886 dbSNP
rs185061660 2887 dbSNP
rs747319929 2895 dbSNP
rs780123174 2901 dbSNP
rs778731325 2902 dbSNP
rs1268442749 2908 dbSNP
rs1479540462 2912 dbSNP
rs1027598588 2913 dbSNP
rs539423215 2914 dbSNP
rs929730775 2915 dbSNP
rs1403150370 2918 dbSNP
rs758808204 2923 dbSNP
rs994342447 2929 dbSNP
rs1405429977 2934 dbSNP
rs1322377433 2935 dbSNP
rs570928062 2940 dbSNP
rs1463471941 2944 dbSNP
rs1371199636 2945 dbSNP
rs1187765848 2948 dbSNP
rs1341491222 2949 dbSNP
rs1454539429 2951 dbSNP
rs1255180689 2954 dbSNP
rs750753535 2957 dbSNP
rs1451211291 2961 dbSNP
rs1359160399 2964 dbSNP
rs1229400367 2973 dbSNP
rs551055975 2974 dbSNP
rs1040816462 2982 dbSNP
rs376279481 2985 dbSNP
rs1251365411 2986 dbSNP
rs1197573090 2990 dbSNP
rs890101541 2996 dbSNP
rs1446187799 2997 dbSNP
rs779427118 3002 dbSNP
rs757712646 3010 dbSNP
rs910902637 3016 dbSNP
rs73265494 3017 dbSNP
rs1274547094 3019 dbSNP
rs763592687 3023 dbSNP
rs1235556379 3025 dbSNP
rs1350480769 3027 dbSNP
rs1298408180 3033 dbSNP
rs1421036692 3033 dbSNP
rs1382008422 3037 dbSNP
rs528052487 3037 dbSNP
rs1316598604 3043 dbSNP
rs1433890494 3045 dbSNP
rs1330087406 3049 dbSNP
rs913051209 3051 dbSNP
rs989084457 3052 dbSNP
rs960148143 3062 dbSNP
rs1246103870 3064 dbSNP
rs914995858 3067 dbSNP
rs989723118 3070 dbSNP
rs928684438 3072 dbSNP
rs1242462556 3076 dbSNP
rs1286989104 3078 dbSNP
rs1328950314 3079 dbSNP
rs980165211 3093 dbSNP
rs1442824109 3094 dbSNP
rs970003716 3097 dbSNP
rs1182883179 3099 dbSNP
rs1241257024 3102 dbSNP
rs1016238352 3113 dbSNP
rs981973047 3123 dbSNP
rs1392618661 3124 dbSNP
rs755576327 3124 dbSNP
rs1404748991 3125 dbSNP
rs775244820 3125 dbSNP
rs1453888096 3126 dbSNP
rs1336621738 3130 dbSNP
rs1381292560 3131 dbSNP
rs752453375 3134 dbSNP
rs1335257404 3136 dbSNP
rs571263039 3140 dbSNP
rs1258030882 3142 dbSNP
rs1396693453 3142 dbSNP
rs761107157 3143 dbSNP
rs1202867626 3145 dbSNP
rs561841628 3146 dbSNP
rs1261173969 3151 dbSNP
rs1026477928 3157 dbSNP
rs1458986398 3165 dbSNP
rs549812740 3169 dbSNP
rs998051321 3170 dbSNP
rs181058146 3176 dbSNP
rs1040786674 3184 dbSNP
rs1006661675 3186 dbSNP
rs1200510325 3188 dbSNP
rs1377891512 3193 dbSNP
rs897298508 3199 dbSNP
rs1176238162 3200 dbSNP
rs528402346 3200 dbSNP
rs189212522 3201 dbSNP
rs1299275948 3203 dbSNP
rs1395827235 3204 dbSNP
rs947316829 3209 dbSNP
rs1389801423 3221 dbSNP
rs913180331 3224 dbSNP
rs187202563 3229 dbSNP
rs1278647310 3231 dbSNP
rs1319765824 3245 dbSNP
rs1199146293 3249 dbSNP
rs1053046132 3252 dbSNP
rs1479359100 3259 dbSNP
rs1343933674 3261 dbSNP
rs1267601089 3271 dbSNP
rs576722729 3279 dbSNP
rs182210498 3284 dbSNP
rs931628009 3289 dbSNP
rs1348053134 3293 dbSNP
rs980134215 3296 dbSNP
rs893555706 3306 dbSNP
rs970141512 3307 dbSNP
rs1404516739 3310 dbSNP
rs935185483 3318 dbSNP
rs766627342 3323 dbSNP
rs909205940 3332 dbSNP
rs1415345740 3334 dbSNP
rs1377136866 3342 dbSNP
rs923800750 3343 dbSNP
rs1294755147 3347 dbSNP
rs1331957790 3349 dbSNP
rs985232577 3350 dbSNP
rs771458117 3359 dbSNP
rs188946591 3361 dbSNP
rs950748321 3362 dbSNP
rs1026946726 3364 dbSNP
rs567455906 3365 dbSNP
rs1160493582 3367 dbSNP
rs1471676669 3370 dbSNP
rs997790143 3373 dbSNP
rs1490049507 3374 dbSNP
rs949340862 3383 dbSNP
rs966175116 3386 dbSNP
rs1017809194 3387 dbSNP
rs1006631882 3391 dbSNP
rs991228709 3393 dbSNP
rs1419257541 3395 dbSNP
rs1427199487 3396 dbSNP
rs1059848 3401 dbSNP
rs1476474090 3401 dbSNP
rs889573420 3403 dbSNP
rs952707205 3407 dbSNP
rs1385900348 3409 dbSNP
rs920016837 3413 dbSNP
rs972787889 3416 dbSNP
rs1209923667 3422 dbSNP
rs1042741604 3423 dbSNP
rs1431193282 3424 dbSNP
rs1287996220 3429 dbSNP
rs1447914265 3431 dbSNP
rs1359617955 3438 dbSNP
rs1397658588 3442 dbSNP
rs1315679178 3446 dbSNP
rs1284568022 3447 dbSNP
rs367941697 3452 dbSNP
rs1287717028 3469 dbSNP
rs1317073978 3471 dbSNP
rs891468822 3473 dbSNP
rs1326582200 3475 dbSNP
rs184675673 3479 dbSNP
rs1485116413 3485 dbSNP
rs1184075020 3486 dbSNP
rs938631492 3499 dbSNP
rs766446182 3500 dbSNP
rs1028541383 3501 dbSNP
rs1357364357 3503 dbSNP
rs73265491 3507 dbSNP
rs1343172294 3510 dbSNP
rs1447083616 3511 dbSNP
rs1467439543 3512 dbSNP
rs1345538937 3514 dbSNP
rs535619811 3520 dbSNP
rs773015600 3523 dbSNP
rs1455866462 3524 dbSNP
rs1373457272 3528 dbSNP
rs1222812148 3529 dbSNP
rs1388093418 3539 dbSNP
rs1281758886 3543 dbSNP
rs768834948 3545 dbSNP
rs948800415 3552 dbSNP
rs747034637 3553 dbSNP
rs573503312 3558 dbSNP
rs1264298590 3560 dbSNP
rs1476218102 3560 dbSNP
rs902266001 3560 dbSNP
rs1412322002 3567 dbSNP
rs1240048034 3568 dbSNP
rs1470569809 3572 dbSNP
rs909342947 3579 dbSNP
rs559508291 3581 dbSNP
rs916491011 3589 dbSNP
rs1055020845 3592 dbSNP
rs931322664 3593 dbSNP
rs1354582954 3594 dbSNP
rs553346510 3601 dbSNP
rs1440897411 3602 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uugauAUGUUGGAGGAUGGAGu 5'
               |:|||||| ||||||| 
Target 5' ----uUGCAACCU-CUACCUCc 3'
 		1 - 17
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000500945.2 | 3UTR | UUGCAACCUCUACCUCCCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.257 0.02 -0.277 0.02 59 Click to see details
BLCA -0.352 0.08 -0.224 0.19 18 Click to see details
BRCA 0.156 0.08 0.138 0.11 84 Click to see details
KICH -0.234 0.13 -0.140 0.25 25 Click to see details
PAAD -0.71 0.15 -0.400 0.3 4 Click to see details
CESC -0.842 0.18 -1.000 0.5 3 Click to see details
PCPG -0.755 0.23 -0.500 0.33 3 Click to see details
HNSC -0.11 0.24 -0.115 0.23 42 Click to see details
COAD 0.195 0.32 0.214 0.31 8 Click to see details
KIRP 0.068 0.36 0.138 0.23 32 Click to see details
STAD 0.065 0.36 0.077 0.34 32 Click to see details
LUAD -0.094 0.39 -0.070 0.41 12 Click to see details
UCEC -0.066 0.39 -0.104 0.34 19 Click to see details
PRAD -0.033 0.41 0.009 0.48 50 Click to see details
CHOL -0.055 0.44 0.050 0.45 9 Click to see details
ESCA 0.044 0.45 0.227 0.25 11 Click to see details
KIRC -0.012 0.46 -0.050 0.34 68 Click to see details
LIHC -0.011 0.47 0.069 0.32 49 Click to see details
LUSC 0.012 0.47 0.005 0.49 38 Click to see details
LUSC 0.012 0.47 0.005 0.49 38 Click to see details
LUSC 0.012 0.47 0.005 0.49 38 Click to see details
581 hsa-let-7e-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT002081 HMGA2 high mobility group AT-hook 2 5 5
MIRT003932 EIF3J eukaryotic translation initiation factor 3 subunit J 2 1
MIRT004469 SMC1A structural maintenance of chromosomes 1A 4 7
MIRT005718 WNT1 Wnt family member 1 4 1
MIRT006122 CCND1 cyclin D1 5 4
MIRT006404 MPL MPL proto-oncogene, thrombopoietin receptor 1 1
MIRT032098 RABGAP1L RAB GTPase activating protein 1 like 1 1
MIRT032099 DAD1 defender against cell death 1 1 1
MIRT032100 MYCN MYCN proto-oncogene, bHLH transcription factor 4 2
MIRT051413 WDR67 TBC1 domain family member 31 1 1
MIRT051414 FAM219B family with sequence similarity 219 member B 1 1
MIRT051415 C11orf91 chromosome 11 open reading frame 91 1 1
MIRT051416 CENPP centromere protein P 1 1
MIRT051417 TMEM107 transmembrane protein 107 1 1
MIRT051418 SREBF1 sterol regulatory element binding transcription factor 1 1 1
MIRT051419 DAAM1 dishevelled associated activator of morphogenesis 1 1 1
MIRT051420 DGCR8 DGCR8, microprocessor complex subunit 1 1
MIRT051421 RAP1A RAP1A, member of RAS oncogene family 1 1
MIRT051422 RPA1 replication protein A1 1 1
MIRT051423 SKIV2L Ski2 like RNA helicase 1 1
MIRT051424 AGO1 argonaute 1, RISC catalytic component 4 2
MIRT051425 RPS27 ribosomal protein S27 1 1
MIRT051426 ARNT2 aryl hydrocarbon receptor nuclear translocator 2 1 1
MIRT051427 GPM6B glycoprotein M6B 1 1
MIRT051428 TTLL12 tubulin tyrosine ligase like 12 1 1
MIRT051429 HIST2H2BF histone cluster 2 H2B family member f 1 1
MIRT051430 CELF2 CUGBP Elav-like family member 2 1 1
MIRT051431 AGO2 argonaute 2, RISC catalytic component 1 1
MIRT051432 VPS13D vacuolar protein sorting 13 homolog D 1 1
MIRT051433 RPL10 ribosomal protein L10 1 1
MIRT051434 SPCS2 signal peptidase complex subunit 2 1 1
MIRT051435 DCAF8 DDB1 and CUL4 associated factor 8 1 1
MIRT051436 CTC1 CST telomere replication complex component 1 1 1
MIRT051437 NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1 1
MIRT051438 PHF3 PHD finger protein 3 1 1
MIRT051439 TUBA1B tubulin alpha 1b 1 1
MIRT051440 SHANK1 SH3 and multiple ankyrin repeat domains 1 1 1
MIRT051441 SKA2 spindle and kinetochore associated complex subunit 2 1 1
MIRT051442 SPTBN1 spectrin beta, non-erythrocytic 1 1 1
MIRT051443 ND2 MTND2 1 1
MIRT051444 MED13L mediator complex subunit 13 like 1 1
MIRT051445 RCOR3 REST corepressor 3 1 1
MIRT051446 MACF1 microtubule-actin crosslinking factor 1 1 1
MIRT051447 RDX radixin 2 5
MIRT051448 PCBP2 poly(rC) binding protein 2 1 1
MIRT051449 UBAP2L ubiquitin associated protein 2 like 1 1
MIRT051450 CDCA3 cell division cycle associated 3 1 1
MIRT051451 CABLES1 Cdk5 and Abl enzyme substrate 1 1 1
MIRT051452 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1 1
MIRT051453 C12orf49 chromosome 12 open reading frame 49 1 1
MIRT051454 TIMP3 TIMP metallopeptidase inhibitor 3 1 1
MIRT051455 WBSCR16 RCC1 like 1 1
MIRT051456 SLC2A11 solute carrier family 2 member 11 1 1
MIRT051457 NF1 neurofibromin 1 1 1
MIRT051458 LRRC8A leucine rich repeat containing 8 VRAC subunit A 1 1
MIRT051459 RUNX1T1 RUNX1 translocation partner 1 1 1
MIRT051460 DTNB dystrobrevin beta 1 1
MIRT051461 SCMH1 Scm polycomb group protein homolog 1 1 1
MIRT051462 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma 1 1
MIRT051463 RHBDD2 rhomboid domain containing 2 1 1
MIRT051464 ND5 NADH dehydrogenase, subunit 5 (complex I) 1 1
MIRT051465 NDST1 N-deacetylase and N-sulfotransferase 1 1 1
MIRT051466 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 5
MIRT051467 EIF4A1 eukaryotic translation initiation factor 4A1 1 1
MIRT051468 BAHCC1 BAH domain and coiled-coil containing 1 1 1
MIRT051469 CARM1 coactivator associated arginine methyltransferase 1 1 1
MIRT051470 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 1 1
MIRT051471 ND3 NADH dehydrogenase, subunit 3 (complex I) 1 1
MIRT051472 PIGS phosphatidylinositol glycan anchor biosynthesis class S 1 1
MIRT051473 ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1 1
MIRT051474 RPN2 ribophorin II 1 1
MIRT051475 RPL12 ribosomal protein L12 1 1
MIRT051476 NME4 NME/NM23 nucleoside diphosphate kinase 4 1 1
MIRT051477 IVD isovaleryl-CoA dehydrogenase 1 1
MIRT051478 JAZF1 JAZF zinc finger 1 1 1
MIRT051479 ND4 NADH dehydrogenase, subunit 4 (complex I) 1 1
MIRT051480 VARS valyl-tRNA synthetase 1 1
MIRT051481 RNF26 ring finger protein 26 1 1
MIRT051482 LHFPL2 LHFPL tetraspan subfamily member 2 1 1
MIRT051483 ARCN1 archain 1 1 1
MIRT051484 COX1 cytochrome c oxidase subunit I 1 1
MIRT051485 SLC12A4 solute carrier family 12 member 4 1 1
MIRT051486 AEBP2 AE binding protein 2 1 1
MIRT051487 PET112 glutamyl-tRNA amidotransferase subunit B 1 1
MIRT051488 UROC1 urocanate hydratase 1 1 1
MIRT051489 IGF1R insulin like growth factor 1 receptor 5 10
MIRT051490 BSDC1 BSD domain containing 1 1 1
MIRT051491 PTK2 protein tyrosine kinase 2 1 1
MIRT051492 CDC5L cell division cycle 5 like 1 1
MIRT051493 EN2 engrailed homeobox 2 1 1
MIRT051494 SSB Sjogren syndrome antigen B 1 1
MIRT051495 SLCO3A1 solute carrier organic anion transporter family member 3A1 1 1
MIRT051496 RRAGC Ras related GTP binding C 1 1
MIRT051497 ZNF236 zinc finger protein 236 1 1
MIRT051498 SEMA4B semaphorin 4B 1 1
MIRT051499 SERBP1 SERPINE1 mRNA binding protein 1 1 1
MIRT051500 XIAP X-linked inhibitor of apoptosis 1 1
MIRT051501 GTF2I general transcription factor IIi 1 1
MIRT051502 JMJD1C jumonji domain containing 1C 1 1
MIRT051503 OTUD5 OTU deubiquitinase 5 1 1
MIRT051504 NOLC1 nucleolar and coiled-body phosphoprotein 1 1 1
MIRT051505 PPIG peptidylprolyl isomerase G 1 1
MIRT051506 PSMD2 proteasome 26S subunit, non-ATPase 2 1 1
MIRT051507 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1 1
MIRT051508 VAMP2 vesicle associated membrane protein 2 1 1
MIRT051509 LSR lipolysis stimulated lipoprotein receptor 1 1
MIRT051510 KIAA0355 KIAA0355 1 1
MIRT051511 RPSA ribosomal protein SA 1 1
MIRT051512 DCAF6 DDB1 and CUL4 associated factor 6 1 1
MIRT051513 UHRF1BP1 UHRF1 binding protein 1 1 1
MIRT051514 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1 1
MIRT051515 PIGP phosphatidylinositol glycan anchor biosynthesis class P 1 1
MIRT051516 LMLN leishmanolysin like peptidase 1 1
MIRT051517 PPP2R1A protein phosphatase 2 scaffold subunit Aalpha 1 1
MIRT051518 HIPK1 homeodomain interacting protein kinase 1 1 1
MIRT051519 SERF2 small EDRK-rich factor 2 1 1
MIRT051520 RBM4 RNA binding motif protein 4 1 1
MIRT051521 RBM14 RNA binding motif protein 14 1 1
MIRT051522 HMGB1 high mobility group box 1 1 1
MIRT051523 GMPS guanine monophosphate synthase 1 1
MIRT051524 DIAPH1 diaphanous related formin 1 1 1
MIRT051525 STAM signal transducing adaptor molecule 1 1
MIRT051526 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 1 1
MIRT051527 APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 1 1
MIRT051528 MARCH5 membrane associated ring-CH-type finger 5 1 1
MIRT051529 SQLE squalene epoxidase 1 1
MIRT051530 TIMM50 translocase of inner mitochondrial membrane 50 1 1
MIRT051531 NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 1 1
MIRT051532 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 1 1
MIRT051533 NRSN2 neurensin 2 1 1
MIRT051534 SALL1 spalt like transcription factor 1 1 1
MIRT051535 COX3 cytochrome c oxidase III 1 1
MIRT051536 RABL6 RAB, member RAS oncogene family like 6 1 1
MIRT051537 SUPT4H1 SPT4 homolog, DSIF elongation factor subunit 1 1
MIRT051538 PACS2 phosphofurin acidic cluster sorting protein 2 1 1
MIRT051539 MTMR14 myotubularin related protein 14 1 1
MIRT051540 LUZP1 leucine zipper protein 1 1 1
MIRT051541 PFAS phosphoribosylformylglycinamidine synthase 1 1
MIRT051542 SUZ12 SUZ12 polycomb repressive complex 2 subunit 1 1
MIRT051543 PAPD4 poly(A) RNA polymerase D4, non-canonical 1 1
MIRT051544 QSOX1 quiescin sulfhydryl oxidase 1 1 1
MIRT051545 SPATA13 spermatogenesis associated 13 1 1
MIRT051546 DHX57 DExH-box helicase 57 1 1
MIRT051547 KATNB1 katanin regulatory subunit B1 1 1
MIRT051548 COL6A1 collagen type VI alpha 1 chain 1 1
MIRT051549 DHX15 DEAH-box helicase 15 1 1
MIRT051550 MTCH2 mitochondrial carrier 2 1 1
MIRT051551 KIAA0100 KIAA0100 1 1
MIRT051552 SUGP2 SURP and G-patch domain containing 2 1 1
MIRT051553 NCLN nicalin 1 1
MIRT051554 ATXN2L ataxin 2 like 1 1
MIRT051555 CHD9 chromodomain helicase DNA binding protein 9 1 1
MIRT051556 PES1 pescadillo ribosomal biogenesis factor 1 1 1
MIRT051557 NUP155 nucleoporin 155 2 7
MIRT051558 GNG5 G protein subunit gamma 5 2 3
MIRT051559 ARHGAP19 Rho GTPase activating protein 19 1 1
MIRT051560 MTFR1 mitochondrial fission regulator 1 1 1
MIRT051561 IRS2 insulin receptor substrate 2 2 1
MIRT051562 IRS4 insulin receptor substrate 4 1 1
MIRT051563 PPP1R10 protein phosphatase 1 regulatory subunit 10 1 1
MIRT051564 ZNF284 zinc finger protein 284 1 1
MIRT051565 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 1 1
MIRT051566 SCD stearoyl-CoA desaturase 1 1
MIRT051567 FDPS farnesyl diphosphate synthase 1 1
MIRT051568 KRBOX4 KRAB box domain containing 4 1 1
MIRT051569 BRI3 brain protein I3 1 1
MIRT051570 CHD7 chromodomain helicase DNA binding protein 7 1 1
MIRT051571 PYCR1 pyrroline-5-carboxylate reductase 1 1 1
MIRT051572 SMAP2 small ArfGAP2 1 1
MIRT051573 WDFY3 WD repeat and FYVE domain containing 3 1 1
MIRT051574 CRK CRK proto-oncogene, adaptor protein 1 1
MIRT051575 SRSF2 serine and arginine rich splicing factor 2 1 1
MIRT051576 PGD phosphogluconate dehydrogenase 1 1
MIRT051577 RMND5A required for meiotic nuclear division 5 homolog A 1 1
MIRT051578 ZNF652 zinc finger protein 652 1 1
MIRT051579 PSMA6 proteasome subunit alpha 6 1 1
MIRT051580 SLC38A2 solute carrier family 38 member 2 1 1
MIRT051581 LRRC41 leucine rich repeat containing 41 1 1
MIRT051582 RANBP2 RAN binding protein 2 1 1
MIRT051583 SVIL supervillin 1 1
MIRT051584 CCNG1 cyclin G1 1 1
MIRT051585 ZNF256 zinc finger protein 256 1 1
MIRT051586 COPG1 coatomer protein complex subunit gamma 1 1 1
MIRT051587 PDCD11 programmed cell death 11 1 1
MIRT051588 CNBP CCHC-type zinc finger nucleic acid binding protein 1 1
MIRT051589 USP37 ubiquitin specific peptidase 37 1 1
MIRT051590 UBE2V2 ubiquitin conjugating enzyme E2 V2 1 1
MIRT051591 UBE2H ubiquitin conjugating enzyme E2 H 1 1
MIRT051592 LMNA lamin A/C 1 1
MIRT051593 STAT3 signal transducer and activator of transcription 3 1 1
MIRT051594 TRPV1 transient receptor potential cation channel subfamily V member 1 1 1
MIRT051595 MATR3 matrin 3 1 1
MIRT051596 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1 1
MIRT051597 HS6ST2 heparan sulfate 6-O-sulfotransferase 2 1 1
MIRT051598 WDR48 WD repeat domain 48 1 1
MIRT051599 RBM8A RNA binding motif protein 8A 1 1
MIRT051600 SCYL1 SCY1 like pseudokinase 1 1 1
MIRT051601 C19orf48 chromosome 19 open reading frame 48 1 1
MIRT051602 FOXD4L6 forkhead box D4 like 6 1 1
MIRT051603 PIGN phosphatidylinositol glycan anchor biosynthesis class N 1 1
MIRT051604 SPCS3 signal peptidase complex subunit 3 1 1
MIRT051605 TNFAIP1 TNF alpha induced protein 1 1 1
MIRT051606 MS4A10 membrane spanning 4-domains A10 1 1
MIRT051607 MSMO1 methylsterol monooxygenase 1 1 1
MIRT051608 ARID1A AT-rich interaction domain 1A 1 1
MIRT051609 NCKIPSD NCK interacting protein with SH3 domain 2 5
MIRT051610 NCBP1 nuclear cap binding protein subunit 1 1 1
MIRT051611 COX16 COX16, cytochrome c oxidase assembly homolog 1 1
MIRT051612 NUDT8 nudix hydrolase 8 1 1
MIRT051613 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT051614 TXNRD1 thioredoxin reductase 1 1 1
MIRT051615 ELMSAN1 ELM2 and Myb/SANT domain containing 1 1 1
MIRT051616 CTSA cathepsin A 1 1
MIRT051617 PRRC2A proline rich coiled-coil 2A 1 1
MIRT051618 SPAG9 sperm associated antigen 9 1 1
MIRT051619 AGMAT agmatinase 1 1
MIRT051620 NCKAP5L NCK associated protein 5 like 1 1
MIRT051621 ZFP62 ZFP62 zinc finger protein 1 1
MIRT051622 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1 1
MIRT051623 POLR3D RNA polymerase III subunit D 2 3
MIRT051624 PRPF8 pre-mRNA processing factor 8 1 1
MIRT051625 ATP6 ATP synthase F0 subunit 6 1 1
MIRT051626 ZFAND5 zinc finger AN1-type containing 5 1 1
MIRT051627 BAZ1B bromodomain adjacent to zinc finger domain 1B 1 1
MIRT051628 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT051629 BMP2K BMP2 inducible kinase 1 1
MIRT051630 SPN sialophorin 1 1
MIRT051631 PA2G4 proliferation-associated 2G4 1 1
MIRT051632 RPRD2 regulation of nuclear pre-mRNA domain containing 2 1 1
MIRT051633 TUBB4B tubulin beta 4B class IVb 1 1
MIRT051634 TRRAP transformation/transcription domain associated protein 1 1
MIRT051635 SLCO4A1 solute carrier organic anion transporter family member 4A1 1 1
MIRT051636 CCRN4L nocturnin 1 1
MIRT051637 USE1 unconventional SNARE in the ER 1 1 1
MIRT051638 STARD7 StAR related lipid transfer domain containing 7 1 1
MIRT051639 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 3
MIRT051640 CLTC clathrin heavy chain 1 1
MIRT051641 TERF1 telomeric repeat binding factor 1 1 1
MIRT051642 PAX3 paired box 3 1 1
MIRT051643 CCDC97 coiled-coil domain containing 97 1 1
MIRT051644 HLA-C major histocompatibility complex, class I, C 1 1
MIRT051645 GTPBP8 GTP binding protein 8 (putative) 1 1
MIRT051646 VGLL4 vestigial like family member 4 1 1
MIRT051647 ANKRD40 ankyrin repeat domain 40 1 1
MIRT051648 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 1 1
MIRT051649 ND1 NADH dehydrogenase, subunit 1 (complex I) 1 1
MIRT051650 DSP desmoplakin 1 1
MIRT051651 UBN2 ubinuclein 2 1 1
MIRT051652 ZNF805 zinc finger protein 805 1 1
MIRT051653 RBBP4 RB binding protein 4, chromatin remodeling factor 1 1
MIRT051654 OCLN occludin 1 1
MIRT051655 CBX5 chromobox 5 2 3
MIRT051656 AMPD2 adenosine monophosphate deaminase 2 1 1
MIRT051657 MKI67 marker of proliferation Ki-67 1 1
MIRT051658 SUB1 SUB1 homolog, transcriptional regulator 1 1
MIRT051659 RSL1D1 ribosomal L1 domain containing 1 1 1
MIRT051660 SEC23IP SEC23 interacting protein 1 1
MIRT051661 RNMT RNA guanine-7 methyltransferase 1 1
MIRT051662 SGSM3 small G protein signaling modulator 3 1 1
MIRT051663 ZFP3 ZFP3 zinc finger protein 1 1
MIRT051664 GLUL glutamate-ammonia ligase 1 1
MIRT051665 POLD1 DNA polymerase delta 1, catalytic subunit 1 1
MIRT051666 WDR4 WD repeat domain 4 1 1
MIRT051667 PPP1R2 protein phosphatase 1 regulatory inhibitor subunit 2 1 1
MIRT051668 RAI2 retinoic acid induced 2 1 1
MIRT051669 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 1 1
MIRT051670 UTP15 UTP15, small subunit processome component 1 1
MIRT051671 THADA THADA, armadillo repeat containing 1 1
MIRT051672 ZNF451 zinc finger protein 451 1 1
MIRT051673 CREBBP CREB binding protein 1 1
MIRT051674 ZNF770 zinc finger protein 770 1 1
MIRT051675 CLDN4 claudin 4 1 1
MIRT051676 ZKSCAN7 zinc finger with KRAB and SCAN domains 7 1 1
MIRT051677 NICN1 nicolin 1 1 1
MIRT051678 RPLP2 ribosomal protein lateral stalk subunit P2 1 1
MIRT051679 DCBLD2 discoidin, CUB and LCCL domain containing 2 1 1
MIRT051680 IRGQ immunity related GTPase Q 1 1
MIRT051681 CA5B carbonic anhydrase 5B 1 1
MIRT051682 COX14 COX14, cytochrome c oxidase assembly factor 1 1
MIRT051683 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT051684 RPL27A ribosomal protein L27a 1 1
MIRT051685 CWC15 CWC15 spliceosome associated protein homolog 1 1
MIRT051686 NT5DC2 5'-nucleotidase domain containing 2 1 1
MIRT051687 OR7D2 olfactory receptor family 7 subfamily D member 2 1 1
MIRT051688 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 1 1
MIRT051689 NUDT15 nudix hydrolase 15 1 1
MIRT051690 CDH18 cadherin 18 1 1
MIRT051691 FAM160B1 family with sequence similarity 160 member B1 1 1
MIRT051692 DZIP1 DAZ interacting zinc finger protein 1 1 1
MIRT051693 TDRD7 tudor domain containing 7 1 1
MIRT051694 TCF4 transcription factor 4 1 1
MIRT051695 ENSA endosulfine alpha 1 1
MIRT051696 GTF3C1 general transcription factor IIIC subunit 1 1 1
MIRT051697 TNFRSF1A TNF receptor superfamily member 1A 1 1
MIRT051698 CCDC113 coiled-coil domain containing 113 1 1
MIRT051699 MYO9B myosin IXB 1 1
MIRT051700 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 1 1
MIRT051701 PRAMEF13 PRAME family member 13 1 1
MIRT051702 PMPCA peptidase, mitochondrial processing alpha subunit 2 5
MIRT051703 MRPS2 mitochondrial ribosomal protein S2 1 1
MIRT051704 RACGAP1 Rac GTPase activating protein 1 1 1
MIRT051705 CCDC106 coiled-coil domain containing 106 1 1
MIRT051706 CYP2B6 cytochrome P450 family 2 subfamily B member 6 1 1
MIRT051707 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 3
MIRT051708 PSME4 proteasome activator subunit 4 1 1
MIRT051709 SETD1A SET domain containing 1A 1 1
MIRT054561 MMP9 matrix metallopeptidase 9 3 1
MIRT054579 IGF1 insulin like growth factor 1 3 1
MIRT063195 ADIPOR2 adiponectin receptor 2 2 2
MIRT065687 ESPL1 extra spindle pole bodies like 1, separase 2 4
MIRT067399 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT068154 TXLNA taxilin alpha 2 2
MIRT068528 NHLRC3 NHL repeat containing 3 2 6
MIRT068789 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073006 ARID3B AT-rich interaction domain 3B 2 6
MIRT076223 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT077616 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT080398 ONECUT2 one cut homeobox 2 2 2
MIRT083300 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084976 BACH1 BTB domain and CNC homolog 1 2 2
MIRT094160 PCGF3 polycomb group ring finger 3 2 6
MIRT094460 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT095766 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT100094 ABT1 activator of basal transcription 1 2 8
MIRT112242 MDM4 MDM4, p53 regulator 2 4
MIRT118586 STK4 serine/threonine kinase 4 2 2
MIRT120921 PDE12 phosphodiesterase 12 2 8
MIRT123317 CALU calumenin 2 2
MIRT152272 TNFSF9 TNF superfamily member 9 2 2
MIRT153847 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168583 HMGA1 high mobility group AT-hook 1 2 4
MIRT180603 CRY2 cryptochrome circadian clock 2 2 2
MIRT187717 SUOX sulfite oxidase 2 2
MIRT191404 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193101 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215720 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218815 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240330 UBXN2B UBX domain protein 2B 2 2
MIRT243473 TRIM71 tripartite motif containing 71 2 2
MIRT244069 EDN1 endothelin 1 2 2
MIRT252330 SALL3 spalt like transcription factor 3 2 2
MIRT255314 CDV3 CDV3 homolog 2 2
MIRT259277 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259479 TXLNG taxilin gamma 2 2
MIRT260707 CLDN12 claudin 12 2 6
MIRT264693 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT266212 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266626 CHTOP chromatin target of PRMT1 2 2
MIRT268839 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT294446 ZNF264 zinc finger protein 264 2 2
MIRT297013 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT297443 SLC20A1 solute carrier family 20 member 1 2 4
MIRT300037 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300893 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303320 MXD1 MAX dimerization protein 1 2 2
MIRT309846 NAT8L N-acetyltransferase 8 like 2 2
MIRT322428 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324731 ACER2 alkaline ceramidase 2 2 2
MIRT402057 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437395 LIN28A lin-28 homolog A 4 1
MIRT437396 AURKB aurora kinase B 4 1
MIRT437435 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2 1
MIRT438632 TNFRSF10B TNF receptor superfamily member 10b 2 1
MIRT439135 MYC MYC proto-oncogene, bHLH transcription factor 0 1
MIRT442020 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445658 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447136 KIF27 kinesin family member 27 2 2
MIRT448259 ZNF774 zinc finger protein 774 2 2
MIRT449005 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449953 FMNL3 formin like 3 2 2
MIRT451155 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451624 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451693 C1RL complement C1r subcomponent like 2 2
MIRT452092 NUCB2 nucleobindin 2 2 2
MIRT452431 QDPR quinoid dihydropteridine reductase 2 2
MIRT452943 DISC1 disrupted in schizophrenia 1 2 2
MIRT453401 RHD Rh blood group D antigen 2 6
MIRT454164 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454280 FXN frataxin 2 2
MIRT454539 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454854 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455676 GLO1 glyoxalase I 2 2
MIRT457248 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457677 ZNF587 zinc finger protein 587 2 2
MIRT457887 THEM6 thioesterase superfamily member 6 2 4
MIRT458016 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458279 FUT10 fucosyltransferase 10 2 2
MIRT459736 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460453 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460500 FAM105A family with sequence similarity 105 member A 2 6
MIRT460938 NOA1 nitric oxide associated 1 2 4
MIRT461092 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461169 SLC11A2 solute carrier family 11 member 2 2 4
MIRT461364 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462382 YAE1D1 Yae1 domain containing 1 2 2
MIRT462780 ZNF8 zinc finger protein 8 2 2
MIRT463420 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463662 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464265 VCL vinculin 2 2
MIRT465122 TSC22D2 TSC22 domain family member 2 2 4
MIRT466184 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466722 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469102 RNF144B ring finger protein 144B 2 2
MIRT469714 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470425 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470679 POLR2D RNA polymerase II subunit D 2 4
MIRT470861 PLXND1 plexin D1 2 2
MIRT471271 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471957 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472672 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 2
MIRT472739 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473134 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473234 SMCR7L mitochondrial elongation factor 1 1 4
MIRT473828 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473940 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474022 LRRC20 leucine rich repeat containing 20 2 2
MIRT474502 KLHDC8B kelch domain containing 8B 2 2
MIRT474766 KIAA0930 KIAA0930 2 2
MIRT474905 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475331 IFNLR1 interferon lambda receptor 1 2 2
MIRT475379 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475733 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476548 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476973 FAM83G family with sequence similarity 83 member G 2 4
MIRT477534 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 2 4
MIRT477682 EFHD2 EF-hand domain family member D2 2 2
MIRT481201 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481241 ATXN7L3 ataxin 7 like 3 2 2
MIRT481363 ATG9A autophagy related 9A 2 2
MIRT481388 ATG12 autophagy related 12 2 2
MIRT481652 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481851 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482184 AHR aryl hydrocarbon receptor 2 2
MIRT482220 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485296 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486659 ZNF28 zinc finger protein 28 2 2
MIRT489413 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491867 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492216 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492626 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493323 LIMD2 LIM domain containing 2 2 2
MIRT493901 FAM43A family with sequence similarity 43 member A 2 4
MIRT494263 CEP120 centrosomal protein 120 2 2
MIRT494687 ARID3A AT-rich interaction domain 3A 2 2
MIRT495968 TBC1D19 TBC1 domain family member 19 2 2
MIRT496111 SNX17 sorting nexin 17 2 2
MIRT497875 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498122 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499405 PLCG2 phospholipase C gamma 2 2 4
MIRT499493 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499653 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499942 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499997 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500819 THBS1 thrombospondin 1 2 3
MIRT500902 STRN striatin 2 4
MIRT501118 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501173 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501202 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501241 SEMA4C semaphorin 4C 2 6
MIRT501328 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501355 RNF44 ring finger protein 44 2 4
MIRT501387 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501441 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501759 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501943 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502106 KPNA5 karyopherin subunit alpha 5 2 8
MIRT502130 KMT2D lysine methyltransferase 2D 2 4
MIRT502784 CEP135 centrosomal protein 135 2 2
MIRT502845 CELF1 CUGBP Elav-like family member 1 2 2
MIRT504789 C12orf4 chromosome 12 open reading frame 4 2 2
MIRT505017 ZNF644 zinc finger protein 644 2 2
MIRT506942 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507252 FIGN fidgetin, microtubule severing factor 2 8
MIRT507694 COIL coilin 2 6
MIRT508401 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508665 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508932 AK4 adenylate kinase 4 2 4
MIRT510395 ZNF566 zinc finger protein 566 2 6
MIRT510518 YOD1 YOD1 deubiquitinase 2 6
MIRT511386 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512745 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515954 C9orf156 tRNA methyltransferase O 2 2
MIRT516083 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT523619 FZD9 frizzled class receptor 9 2 4
MIRT523733 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523990 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524113 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525727 SOD2 superoxide dismutase 2 2 2
MIRT527763 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529727 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533187 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536378 LEFTY1 left-right determination factor 1 2 2
MIRT543785 RBM12B RNA binding motif protein 12B 2 4
MIRT543868 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545387 PM20D2 peptidase M20 domain containing 2 2 2
MIRT545890 ZNF200 zinc finger protein 200 2 4
MIRT546334 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547373 MSI2 musashi RNA binding protein 2 2 2
MIRT547579 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548264 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548351 EPHA4 EPH receptor A4 2 2
MIRT548534 DUSP1 dual specificity phosphatase 1 2 2
MIRT548560 DNAL1 dynein axonemal light chain 1 2 2
MIRT548779 COLEC12 collectin subfamily member 12 2 2
MIRT548978 CCNT2 cyclin T2 2 2
MIRT549208 BEND4 BEN domain containing 4 2 4
MIRT549763 ZNF611 zinc finger protein 611 2 6
MIRT549799 KIAA0391 KIAA0391 2 2
MIRT549847 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550898 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551283 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551318 GSG2 histone H3 associated protein kinase 2 6
MIRT551932 AKAP8 A-kinase anchoring protein 8 2 4
MIRT552003 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552410 ZNF460 zinc finger protein 460 2 4
MIRT553013 USP38 ubiquitin specific peptidase 38 2 2
MIRT555550 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555711 PDZD8 PDZ domain containing 8 2 2
MIRT557372 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT557960 FAM222B family with sequence similarity 222 member B 2 2
MIRT559087 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559497 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561772 PEG10 paternally expressed 10 2 2
MIRT564402 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565443 SURF4 surfeit 4 2 2
MIRT566518 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567715 E2F6 E2F transcription factor 6 2 2
MIRT568655 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569498 THYN1 thymocyte nuclear protein 1 2 2
MIRT573820 TGOLN2 trans-golgi network protein 2 2 2
MIRT574363 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574750 GOLGA4 golgin A4 2 2
MIRT574788 FAM104A family with sequence similarity 104 member A 2 2
MIRT576089 Poteg POTE ankyrin domain family, member G 2 2
MIRT576812 Thbs1 thrombospondin 1 2 3
MIRT616370 RWDD1 RWD domain containing 1 2 2
MIRT617851 FMO4 flavin containing monooxygenase 4 2 2
MIRT642394 ZNF556 zinc finger protein 556 2 2
MIRT680519 PRIM2 DNA primase subunit 2 2 2
MIRT680547 ZNF584 zinc finger protein 584 2 2
MIRT680800 ZNF578 zinc finger protein 578 2 2
MIRT680838 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681141 INTS7 integrator complex subunit 7 2 2
MIRT681271 RFC2 replication factor C subunit 2 2 2
MIRT681323 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681359 BRI3BP BRI3 binding protein 2 2
MIRT681506 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681536 ZNF738 zinc finger protein 738 2 2
MIRT681658 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681738 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681797 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681869 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681941 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682102 ITGA3 integrin subunit alpha 3 2 4
MIRT682181 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682238 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682384 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682444 MTX3 metaxin 3 2 2
MIRT682604 CPA4 carboxypeptidase A4 2 2
MIRT682640 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689327 FPR1 formyl peptide receptor 1 2 2
MIRT689730 ATXN2 ataxin 2 2 2
MIRT691036 ZNF799 zinc finger protein 799 2 2
MIRT691935 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694884 ZNF417 zinc finger protein 417 2 2
MIRT695255 ZNF443 zinc finger protein 443 2 2
MIRT695413 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700589 PRSS22 protease, serine 22 2 2
MIRT701428 NHLRC2 NHL repeat containing 2 2 2
MIRT702484 KIAA1328 KIAA1328 2 2
MIRT702715 IPO9 importin 9 2 2
MIRT704028 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704418 CTPS1 CTP synthase 1 2 2
MIRT705750 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712373 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713520 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT731263 FASLG Fas ligand 3 1
MIRT732697 Ccr7 chemokine (C-C motif) receptor 7 2 0
MIRT732700 Snhg12 small nucleolar RNA host gene 12 2 0
MIRT734626 SYT7 synaptotagmin 7 1 0
MIRT755829 UBQLN4 ubiquilin 4 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7e Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
let-7e Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
let-7e Doxorubicin approved 31703 Microarray ovarian cancer 19237188 2009 up-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7e Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 up-regulated
let-7e Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7e 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
let-7e Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse liver 19270793 2009 down-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
let-7e Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 down-regulated
let-7e Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 down-regulated
let-7e 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) NULL 16078949 Microarray hepatocytes 23107762 2013 up-regulated
let-7e Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Doxorubicin 31703 NSC123127 approved resistant High Ovarian Cancer cell line (OV19, TOV21G, TOV112D, FUOV1, C13, OV2008, A2780CP, A2780S, IGROV1, T8, OVCAR5, IMCC3, A2008, OVCAR3, SKOV3, IOSER)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant High Colon Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer tissue and cell line (A2780)
hsa-let-7e Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H1155, H358, H1993)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-let-7e Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor tissue
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Esophageal Adenocarcinoma cell line (OE19)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Breast Cancer tissue and cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Plx-4720 24180719 NSC757438 resistant High Thyroid Cancer cell line (8505c, BCPAP)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive High Colorectal Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, HO8910, ES2, CAOV3, SKOV3)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-8)
hsa-let-7e Daunorubicin 30323 NSC82151 approved resistant High Acute Promyelocytic Leukemia cell line (HL60)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7C)
hsa-let-7e Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Non-Small Cell Lung Cancer cell line (PC-9)
hsa-let-7e Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Regorafenib 11167602 NSC763932 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Ribavirin+Pegylated IFNa-2b resistant tissue (chronic hepatitis C)
hsa-let-7e Exemestane 60198 NSC713563 approved sensitive cell line (MCF-7)
hsa-let-7e 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-let-7e Ethanol+Tamoxifen resistant cell line (LY2)
hsa-let-7e Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-let-7e Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-let-7e Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-let-7e Gemcitabine 60750 NSC613327 approved resistant cell line (HuH28)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (KYSE)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (OE19)
hsa-let-7e Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-let-7e Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-let-7e-5p Alvocidib 5287969 NSC649890 resistant
hsa-let-7e-5p Ethyl, methoxy, prodigisine 135829283 NSC742418 resistant
hsa-let-7e-5p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-let-7e-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e-5p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-let-7e-5p Platinum 23939 resistant High High-Grade Serous Ovarian Cancer tissue
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-let-7e-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-let-7e-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-let-7e-5p Sunitinib 5329102 NSC750690 approved sensitive tissue (clear cell renal cell carcinoma)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-let-7e-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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