pre-miRNA Information
pre-miRNA hsa-let-7e   
Genomic Coordinates chr19: 51692786 - 51692864
Synonyms MIRNLET7E, hsa-let-7e, let-7e, MIRLET7E
Description Homo sapiens let-7e stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-let-7e-5p
Sequence 8| UGAGGUAGGAGGUUGUAUAGUU |29
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1189776118 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol AHR   
Synonyms bHLHe76
Description aryl hydrocarbon receptor
Transcript NM_001621   
Expression
Putative miRNA Targets on AHR
3'UTR of AHR
(miRNA target sites are highlighted)
>AHR|NM_001621|3'UTR
   1 TTCCAAGCCCAATTTTGACCCTGGTTTTTGGATTAAATTAGTTTGTGAAGGATTATGGAAAAATAAAACTGTCACTGTTG
  81 GACGTCAGCAAGTTCACATGGAGGCATTGATGCATGCTATTCACAATTATTCCAAACCAAATTTTAATTTTTGCTTTTAG
 161 AAAAGGGAGTTTAAAAATGGTATCAAAATTACATATACTACAGTCAAGATAGAAAGGGTGCTGCCACGGAGTGGTGAGGT
 241 ACCGTCTACATTTCACATTATTCTGGGCACCACAAAATATACAAAACTTTATCAGGGAAACTAAGATTCTTTTAAATTAG
 321 AAAATATTCTCTATTTGAATTATTTCTGTCACAGTAAAAATAAAATACTTTGAGTTTTGAGCTACTGGATTCTTATTAGT
 401 TCCCCAAATACAAAGTTAGAGAACTAAACTAGTTTTTCCTATCATGTTAACCTCTGCTTTTATCTCAGATGTTAAAATAA
 481 ATGGTTTGGTGCTTTTTATAAAAAGATAATCTCAGTGCTTTCCTCCTTCACTGTTTCATCTAAGTGCCTCACATTTTTTT
 561 CTACCTATAACACTCTAGGATGTATATTTTATATAAAGTATTCTTTTTCTTTTTTAAATTAATATCTTTCTGCACACAAA
 641 TATTATTTGTGTTTCCTAAATCCAACCATTTTCATTAATTCAGGCATATTTTAACTCCACTGCTTACCTACTTTCTTCAG
 721 GTAAAGGGCAAATAATGATCGAAAAAATAATTATTTATTACATAATTTAGTTGTTTCTAGACTATAAATGTTGCTATGTG
 801 CCTTATGTTGAAAAAATTTAAAAGTAAAATGTCTTTCCAAATTATTTCTTAATTATTATAAAAATATTAAGACAATAGCA
 881 CTTAAATTCCTCAACAGTGTTTTCAGAAGAAATAAATATACCACTCTTTACCTTTATTGATATCTCCATGATGATAGTTG
 961 AATGTTGCAATGTGAAAAATCTGCTGTTAACTGCAACCTTGTTTATTAAATTGCAAGAAGCTTTATTTCTAGCTTTTTAA
1041 TTAAGCAAAGCACCCATTTCAATGTGTATAAATTGTCTTTAAAAACTGTTTTAGACCTATAATCCTTGATAATATATTGT
1121 GTTGACTTTATAAATTTCGCTTCTTAGAACAGTGGAAACTATGTGTTTTTCTCATATTTGAGGAGTGTTAAGATTGCAGA
1201 TAGCAAGGTTTGGTGCAAAGTATTGTAATGAGTGAATTGAATGGTGCATTGTATAGATATAATGAACAAAATTATTTGTA
1281 AGATATTTGCAGTTTTTCATTTTAAAAAGTCCATACCTTATATATGCACTTAATTTGTTGGGGCTTTACATACTTTATCA
1361 ATGTGTCTTTCTAAGAAATCAAGTAATGAATCCAACTGCTTAAAGTTGGTATTAATAAAAAGACAACCACATAGTTCGTT
1441 TACCTTCAAACTTTAGGTTTTTTTAATGATATACTGATCTTCATTACCAATAGGCAAATTAATCACCCTACCAACTTTAC
1521 TGTCCTAACATGGTTTAAAAGAAAAAATGACACCATCTTTTATTCTTTTTTTTTTTTTTTTTTGAGAGAGAGTCTTACTC
1601 TGCCGCCCAAACTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAACCTCTACCTCCTGGGTTCAAGTGATTCTCTTGCC
1681 TCAGCCTCCCGAGTTGCTGGGATTACAGGCATGTGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAAACGGGTTT
1761 CACCATGTTGGCCAGACTGGTCTCAAACTCCTGACCTCAGGTGAGCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTAC
1841 AGGCGTGAGCCACTGCATTCAGCTCTTCTTTTCTTTAGATATGAGAGCTGAAGAGCTTAGACACATTTTGCATGTATTAT
1921 TTGAAAATCTGATGGAATCCCAAACTGAGATGTATTAAAATACAATTTTTGGCCGGGTGCAGTGGCTCACGCCTGTAATC
2001 CCAGCACTTGGGGAGGGCGAGGAGGGTGGATCACGAGGTCAAGAGATGGAGACCATCCTGACCAACATGGTGAAACCCTG
2081 TCTCTACTAAAAATACAGAAATTAGCTGGGCATGGTGGCGTGAGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGGA
2161 GAATAGCCTGAACCTGGGAATCGGAGGTTGCAGAGCCAAGATCGCCCCACTGCACTCCAGCCTGGCAATAGACCGAGACT
2241 CCGTCTCCAAAAAAAAAAAAAATACAATTTTTATTTCTTTTACTTTTTTTAGTAAGTTAATGTATATAAAAATGGCTTCG
2321 GACAAAATATCTCTGAGTTCTGTGTATTTTCAGTCAAAACTTTAAACCTGTAGAATCAATTTAAGTGTTGGAAAAAATTT
2401 GTCTGAAACATTTCATAATTTGTTTCCAGCATGAGGTATCTAAGGATTTAGACCAGAGGTCTAGATTAATACTCTATTTT
2481 TACATTTAAACCTTTTATTATAAGTCTTACATAAACCATTTTTGTTACTCTCTTCCACATGTTACTGGATAAATTGTTTA
2561 GTGGAAAATAGGCTTTTTAATCATGAATATGATGACAATCAGTTATACAGTTATAAAATTAAAAGTTTGAAAAGCAATAT
2641 TGTATATTTTTATCTATATAAAATAACTAAAATGTATCTAAGAATAATAAAATCACGTTAAACCAAATACACGTTTGTCT
2721 GTATTGTTAAGTGCCAAACAAAGGATACTTAGTGCACTGCTACATTGTGGGATTTATTTCTAGATGATGTGCACATCTAA
2801 GGATATGGATGTGTCTAATTTAGTCTTTTCCTGTACCAGGTTTTTCTTACAATACCTGAAGACTTACCAGTATTCTAGTG
2881 TATTATGAAGCTTTCAACATTACTATGCACAAACTAGTGTTTTTCGATGTTACTAAATTTTAGGTAAATGCTTTCATGGC
2961 TTTTTTCTTCAAAATGTTACTGCTTACATATATCATGCATAGATTTTTGCTTAAAGTATGATTTATAATATCCTCATTAT
3041 CAAAGTTGTATACAATAATATATAATAAAATAACAAATATGAATAAT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uugauAUGUUGGAGGAUGGAGu 5'
               |:|||||| ||||||| 
Target 5' ctcacTGCAACCT-CTACCTCc 3'
1637 - 1657 168.00 -20.00
2
miRNA  3' uugAUAUGUUGGAGGAUGGAGu 5'
             ||||| ||: ::|||||: 
Target 5' aaaTATACCACTCTTTACCTTt 3'
914 - 935 139.00 -14.40
3
miRNA  3' uugauauGUUGGAGGA-UGGAGu 5'
                 ||| ||||| ||||| 
Target 5' ctggtctCAAACTCCTGACCTCa 3'
1777 - 1799 135.00 -18.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26965536 37 COSMIC
COSN31530848 45 COSMIC
COSN30105743 84 COSMIC
COSN26965535 85 COSMIC
COSN30184559 87 COSMIC
COSN28198047 92 COSMIC
COSN30516972 98 COSMIC
COSN31583655 192 COSMIC
COSN7972647 196 COSMIC
COSN2213444 437 COSMIC
COSN31593240 491 COSMIC
COSN6873630 594 COSMIC
COSN31541826 652 COSMIC
COSN19544553 668 COSMIC
COSN31559455 778 COSMIC
COSN31567898 844 COSMIC
COSN31585882 866 COSMIC
COSN20625836 893 COSMIC
COSN31539995 1054 COSMIC
COSN31530419 1139 COSMIC
COSN31577236 1204 COSMIC
COSN27303499 1318 COSMIC
COSN16551679 1352 COSMIC
COSN25970276 1562 COSMIC
COSN20091523 1563 COSMIC
COSN20091524 1566 COSMIC
COSN32061624 1584 COSMIC
COSN25221168 1619 COSMIC
COSN31537489 2244 COSMIC
COSN8516206 2264 COSMIC
COSN8516207 2266 COSMIC
COSN15863921 2294 COSMIC
COSN31515112 2332 COSMIC
COSN20908521 2388 COSMIC
COSN9981063 2399 COSMIC
COSN31528226 2494 COSMIC
COSN20903366 2549 COSMIC
COSN22479534 2603 COSMIC
COSN31518777 2636 COSMIC
COSN31551159 2655 COSMIC
COSN31548682 2697 COSMIC
COSN22018694 2756 COSMIC
COSN26552177 2814 COSMIC
COSN20103798 2822 COSMIC
rs11400459 2820 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs919837085 5 dbSNP
rs1197906854 6 dbSNP
rs1244827736 9 dbSNP
rs761286924 10 dbSNP
rs374691329 11 dbSNP
rs1388978978 16 dbSNP
rs754268402 21 dbSNP
rs1170978144 22 dbSNP
rs566368932 24 dbSNP
rs1405069819 25 dbSNP
rs778682300 25 dbSNP
rs1321983165 26 dbSNP
rs1211797770 32 dbSNP
rs1444786330 33 dbSNP
rs752196285 33 dbSNP
rs1437431585 38 dbSNP
rs937991861 44 dbSNP
rs1266875654 48 dbSNP
rs369895783 53 dbSNP
rs75852993 66 dbSNP
rs1055567959 68 dbSNP
rs1291336027 71 dbSNP
rs919675053 76 dbSNP
rs536411430 77 dbSNP
rs777705598 79 dbSNP
rs779385845 81 dbSNP
rs752182244 85 dbSNP
rs902668976 92 dbSNP
rs1321252790 111 dbSNP
rs1458857169 112 dbSNP
rs1273916396 125 dbSNP
rs1001444936 127 dbSNP
rs554748277 149 dbSNP
rs1416325932 157 dbSNP
rs1032561194 160 dbSNP
rs569924715 166 dbSNP
rs1484662282 169 dbSNP
rs1203068759 174 dbSNP
rs900786456 176 dbSNP
rs1208860871 178 dbSNP
rs890937935 183 dbSNP
rs943891182 193 dbSNP
rs1322115106 194 dbSNP
rs537568006 196 dbSNP
rs1213058305 201 dbSNP
rs1364781623 202 dbSNP
rs1298582853 203 dbSNP
rs1437446645 207 dbSNP
rs558612240 208 dbSNP
rs187812144 221 dbSNP
rs549479592 228 dbSNP
rs577461634 229 dbSNP
rs1032265308 237 dbSNP
rs1447180964 240 dbSNP
rs986519139 241 dbSNP
rs1015370258 242 dbSNP
rs1012258920 244 dbSNP
rs1321443199 245 dbSNP
rs538437087 249 dbSNP
rs34185983 251 dbSNP
rs1190568552 256 dbSNP
rs781744734 257 dbSNP
rs1267108850 259 dbSNP
rs1202239687 268 dbSNP
rs1341183715 274 dbSNP
rs746262577 278 dbSNP
rs1230805727 282 dbSNP
rs919844283 283 dbSNP
rs1300618252 291 dbSNP
rs190918494 300 dbSNP
rs1387893580 310 dbSNP
rs572307999 317 dbSNP
rs1348562246 321 dbSNP
rs1296941094 324 dbSNP
rs937963170 327 dbSNP
rs984056402 328 dbSNP
rs1296956741 339 dbSNP
rs1015170124 341 dbSNP
rs112720436 347 dbSNP
rs1225389391 349 dbSNP
rs371500854 354 dbSNP
rs542527561 367 dbSNP
rs1269450694 369 dbSNP
rs4987097 374 dbSNP
rs1451428774 376 dbSNP
rs949407378 377 dbSNP
rs1042416532 379 dbSNP
rs1345945079 380 dbSNP
rs1255598576 384 dbSNP
rs902613618 385 dbSNP
rs1314017250 388 dbSNP
rs575929643 389 dbSNP
rs4987098 390 dbSNP
rs1409689932 393 dbSNP
rs936847283 397 dbSNP
rs932321454 405 dbSNP
rs985187432 413 dbSNP
rs1413285600 415 dbSNP
rs912342671 416 dbSNP
rs1557737 420 dbSNP
rs1187461394 421 dbSNP
rs1385327174 424 dbSNP
rs1156880035 425 dbSNP
rs1445867931 432 dbSNP
rs1472196183 435 dbSNP
rs1042653495 443 dbSNP
rs900733850 444 dbSNP
rs1184130770 461 dbSNP
rs1440461387 469 dbSNP
rs1255816980 472 dbSNP
rs1201180913 480 dbSNP
rs1484285516 481 dbSNP
rs1161422440 490 dbSNP
rs1228349327 499 dbSNP
rs755753842 511 dbSNP
rs1401122528 514 dbSNP
rs1320024479 532 dbSNP
rs1290728307 534 dbSNP
rs1231905312 538 dbSNP
rs996859205 543 dbSNP
rs1333105113 545 dbSNP
rs1396197387 546 dbSNP
rs1030601151 547 dbSNP
rs890772168 550 dbSNP
rs1317909255 555 dbSNP
rs936550833 564 dbSNP
rs1389352670 565 dbSNP
rs145866500 579 dbSNP
rs1471689401 581 dbSNP
rs35747095 584 dbSNP
rs1367615996 588 dbSNP
rs1188533735 593 dbSNP
rs1425740136 596 dbSNP
rs1246386818 601 dbSNP
rs895128364 602 dbSNP
rs1465389147 603 dbSNP
rs1012227921 604 dbSNP
rs1025003811 607 dbSNP
rs778637154 625 dbSNP
rs182805874 631 dbSNP
rs1384596660 633 dbSNP
rs187992000 636 dbSNP
rs1015469834 638 dbSNP
rs1294919750 641 dbSNP
rs963567322 643 dbSNP
rs142068538 644 dbSNP
rs1356237060 646 dbSNP
rs1403487527 656 dbSNP
rs961452503 657 dbSNP
rs1389786672 661 dbSNP
rs973929299 670 dbSNP
rs1027263960 678 dbSNP
rs1388611583 679 dbSNP
rs1327446387 686 dbSNP
rs1188160249 687 dbSNP
rs548022230 689 dbSNP
rs1243330073 697 dbSNP
rs1462298894 698 dbSNP
rs192831928 699 dbSNP
rs185229919 704 dbSNP
rs1236890445 711 dbSNP
rs35821518 715 dbSNP
rs1291179365 719 dbSNP
rs953707549 727 dbSNP
rs1340465407 728 dbSNP
rs1272122892 733 dbSNP
rs1227136167 735 dbSNP
rs1365321197 736 dbSNP
rs1470466814 740 dbSNP
rs990676118 741 dbSNP
rs985091711 742 dbSNP
rs187272302 748 dbSNP
rs1368396751 751 dbSNP
rs1388365573 751 dbSNP
rs530446977 752 dbSNP
rs1160156365 756 dbSNP
rs1430594180 771 dbSNP
rs943825442 778 dbSNP
rs747743083 780 dbSNP
rs1477727225 781 dbSNP
rs191990186 790 dbSNP
rs1201642787 803 dbSNP
rs1482285264 806 dbSNP
rs570066639 809 dbSNP
rs1053944014 810 dbSNP
rs1204041439 819 dbSNP
rs1158748937 822 dbSNP
rs922064445 827 dbSNP
rs1274641607 830 dbSNP
rs1053648148 833 dbSNP
rs1343665603 835 dbSNP
rs552343929 846 dbSNP
rs1275371076 849 dbSNP
rs1406636606 849 dbSNP
rs1348428258 857 dbSNP
rs760164874 858 dbSNP
rs1307140308 859 dbSNP
rs916468680 866 dbSNP
rs1356546604 875 dbSNP
rs932186858 876 dbSNP
rs948062591 890 dbSNP
rs1290700752 894 dbSNP
rs567317602 910 dbSNP
rs1174849101 913 dbSNP
rs1046341005 914 dbSNP
rs890717599 919 dbSNP
rs1007888011 921 dbSNP
rs1036736120 923 dbSNP
rs1005408769 924 dbSNP
rs896883325 926 dbSNP
rs1207501424 927 dbSNP
rs1234316762 927 dbSNP
rs753325135 934 dbSNP
rs1278658441 940 dbSNP
rs184812886 942 dbSNP
rs771678938 944 dbSNP
rs1327051023 958 dbSNP
rs1287630791 960 dbSNP
rs1263422194 971 dbSNP
rs1228841027 973 dbSNP
rs1036432974 974 dbSNP
rs959429558 980 dbSNP
rs1277296752 981 dbSNP
rs994976576 984 dbSNP
rs1359847513 997 dbSNP
rs1437852377 999 dbSNP
rs1183937310 1000 dbSNP
rs1338825389 1014 dbSNP
rs778820328 1015 dbSNP
rs1249482772 1026 dbSNP
rs1388617875 1034 dbSNP
rs1160542077 1037 dbSNP
rs1012044928 1040 dbSNP
rs1024840398 1069 dbSNP
rs566425387 1074 dbSNP
rs537585438 1093 dbSNP
rs1199854236 1103 dbSNP
rs1179780924 1107 dbSNP
rs1472239580 1111 dbSNP
rs970658538 1127 dbSNP
rs978045822 1128 dbSNP
rs763747989 1130 dbSNP
rs1467770694 1137 dbSNP
rs374953443 1139 dbSNP
rs1009151164 1140 dbSNP
rs1209210413 1144 dbSNP
rs1170972028 1148 dbSNP
rs1310260194 1156 dbSNP
rs1401611588 1160 dbSNP
rs989948010 1162 dbSNP
rs1019732672 1164 dbSNP
rs1433074751 1167 dbSNP
rs1364462820 1172 dbSNP
rs1310427374 1174 dbSNP
rs1455759624 1175 dbSNP
rs535594414 1177 dbSNP
rs17137616 1178 dbSNP
rs1051965612 1185 dbSNP
rs1385542803 1188 dbSNP
rs1185049691 1209 dbSNP
rs1447138850 1217 dbSNP
rs534747244 1233 dbSNP
rs923690050 1236 dbSNP
rs912144103 1238 dbSNP
rs1333118259 1242 dbSNP
rs1230621685 1245 dbSNP
rs553570759 1247 dbSNP
rs1294221947 1249 dbSNP
rs111430604 1254 dbSNP
rs1206644734 1261 dbSNP
rs989237426 1263 dbSNP
rs896792364 1269 dbSNP
rs1272455082 1270 dbSNP
rs995187890 1279 dbSNP
rs948010453 1283 dbSNP
rs746996503 1287 dbSNP
rs1427371664 1305 dbSNP
rs1389132355 1317 dbSNP
rs1170590142 1318 dbSNP
rs1429756470 1322 dbSNP
rs894929237 1323 dbSNP
rs1265259240 1325 dbSNP
rs753549164 1329 dbSNP
rs1012033201 1330 dbSNP
rs35396548 1330 dbSNP
rs36103566 1345 dbSNP
rs927981655 1346 dbSNP
rs1203317856 1351 dbSNP
rs1341772243 1354 dbSNP
rs1482681404 1358 dbSNP
rs1275596667 1359 dbSNP
rs1024789431 1362 dbSNP
rs1229780863 1378 dbSNP
rs940680426 1384 dbSNP
rs1223036145 1396 dbSNP
rs575922449 1403 dbSNP
rs1220263930 1405 dbSNP
rs1347808017 1406 dbSNP
rs1432388530 1421 dbSNP
rs1306520024 1428 dbSNP
rs1409573398 1438 dbSNP
rs999368018 1439 dbSNP
rs536580143 1445 dbSNP
rs770878878 1450 dbSNP
rs1375371231 1452 dbSNP
rs1036869173 1455 dbSNP
rs1179810460 1458 dbSNP
rs1197061602 1458 dbSNP
rs899215664 1458 dbSNP
rs1482598825 1460 dbSNP
rs1251598764 1463 dbSNP
rs995007231 1465 dbSNP
rs776512509 1466 dbSNP
rs1255441764 1469 dbSNP
rs1377250468 1470 dbSNP
rs1475810976 1473 dbSNP
rs1211479249 1478 dbSNP
rs1170546612 1484 dbSNP
rs958239510 1491 dbSNP
rs1326338965 1492 dbSNP
rs889280205 1502 dbSNP
rs989504029 1507 dbSNP
rs1369313845 1509 dbSNP
rs1429677347 1510 dbSNP
rs1029481957 1511 dbSNP
rs1351411768 1512 dbSNP
rs35618592 1523 dbSNP
rs965434507 1524 dbSNP
rs759331327 1525 dbSNP
rs1393360832 1531 dbSNP
rs999170658 1532 dbSNP
rs1300219522 1537 dbSNP
rs1469848850 1537 dbSNP
rs1408286310 1541 dbSNP
rs879017710 1542 dbSNP
rs556124142 1553 dbSNP
rs912091828 1556 dbSNP
rs371875021 1563 dbSNP
rs1031175059 1565 dbSNP
rs1294761362 1565 dbSNP
rs1208586925 1566 dbSNP
rs1296230251 1566 dbSNP
rs376477618 1566 dbSNP
rs755565130 1566 dbSNP
rs957743596 1567 dbSNP
rs1340761873 1569 dbSNP
rs189275121 1575 dbSNP
rs76416472 1583 dbSNP
rs1267099259 1584 dbSNP
rs1452817548 1584 dbSNP
rs74855965 1584 dbSNP
rs916447423 1584 dbSNP
rs1383954420 1585 dbSNP
rs1456599214 1586 dbSNP
rs1385444958 1588 dbSNP
rs1160128994 1591 dbSNP
rs1456183945 1594 dbSNP
rs1368179254 1599 dbSNP
rs1446533388 1600 dbSNP
rs1208995853 1605 dbSNP
rs1013376000 1606 dbSNP
rs1448119236 1614 dbSNP
rs1465506839 1615 dbSNP
rs71551783 1623 dbSNP
rs1264449061 1627 dbSNP
rs1190680507 1631 dbSNP
rs1356088244 1637 dbSNP
rs1290583429 1638 dbSNP
rs74649209 1642 dbSNP
rs35395879 1643 dbSNP
rs34925659 1653 dbSNP
rs181078878 1660 dbSNP
rs920867062 1667 dbSNP
rs1327007033 1674 dbSNP
rs930968652 1676 dbSNP
rs972051644 1682 dbSNP
rs764882451 1683 dbSNP
rs544890324 1688 dbSNP
rs1388515835 1691 dbSNP
rs1168092923 1692 dbSNP
rs1475776078 1695 dbSNP
rs930749195 1697 dbSNP
rs1050487498 1698 dbSNP
rs1385307647 1705 dbSNP
rs1436837096 1706 dbSNP
rs1269993501 1721 dbSNP
rs1318055732 1729 dbSNP
rs894881276 1730 dbSNP
rs35548334 1732 dbSNP
rs1213545483 1747 dbSNP
rs1046145749 1748 dbSNP
rs1339394106 1750 dbSNP
rs1271866937 1753 dbSNP
rs1230907223 1755 dbSNP
rs1344668949 1758 dbSNP
rs1406518403 1762 dbSNP
rs577017734 1768 dbSNP
rs999317080 1770 dbSNP
rs1410610688 1774 dbSNP
rs1216316427 1777 dbSNP
rs1171363069 1778 dbSNP
rs1477967614 1783 dbSNP
rs1430575662 1787 dbSNP
rs1202110828 1790 dbSNP
rs1031301038 1794 dbSNP
rs1249167492 1795 dbSNP
rs1203307178 1804 dbSNP
rs1314827193 1806 dbSNP
rs893755684 1808 dbSNP
rs1274448040 1814 dbSNP
rs1011319753 1815 dbSNP
rs1243873319 1832 dbSNP
rs999598973 1841 dbSNP
rs1225188001 1843 dbSNP
rs541100448 1845 dbSNP
rs893463678 1845 dbSNP
rs953428454 1846 dbSNP
rs1332324725 1849 dbSNP
rs1023320058 1856 dbSNP
rs1210843501 1858 dbSNP
rs1179123568 1863 dbSNP
rs987531982 1865 dbSNP
rs1246385638 1875 dbSNP
rs969208744 1876 dbSNP
rs1019043711 1883 dbSNP
rs1470331240 1886 dbSNP
rs202198518 1887 dbSNP
rs1422578865 1889 dbSNP
rs1184850581 1890 dbSNP
rs962028086 1891 dbSNP
rs184270935 1906 dbSNP
rs1205424095 1910 dbSNP
rs1433249373 1913 dbSNP
rs1326843078 1917 dbSNP
rs1283248291 1920 dbSNP
rs1224103245 1930 dbSNP
rs1375869203 1932 dbSNP
rs1282632741 1933 dbSNP
rs1413179315 1937 dbSNP
rs1383539258 1941 dbSNP
rs1339292522 1946 dbSNP
rs1459111561 1951 dbSNP
rs1456071113 1955 dbSNP
rs1345079539 1961 dbSNP
rs1160350898 1964 dbSNP
rs1402789895 1966 dbSNP
rs1409791094 1974 dbSNP
rs962172243 1975 dbSNP
rs972295154 1976 dbSNP
rs1156553609 1977 dbSNP
rs920841981 1980 dbSNP
rs930934573 1988 dbSNP
rs1241428137 1991 dbSNP
rs984180740 1992 dbSNP
rs1452804068 1996 dbSNP
rs1288006215 2006 dbSNP
rs1245454290 2008 dbSNP
rs1304074613 2009 dbSNP
rs1317298832 2011 dbSNP
rs1361936584 2013 dbSNP
rs930613250 2019 dbSNP
rs1395392585 2020 dbSNP
rs916220168 2027 dbSNP
rs910611361 2028 dbSNP
rs947740350 2031 dbSNP
rs1046091279 2035 dbSNP
rs1266528394 2036 dbSNP
rs1164991270 2040 dbSNP
rs1426209273 2043 dbSNP
rs1418803197 2044 dbSNP
rs1186972185 2045 dbSNP
rs906297582 2047 dbSNP
rs1328744880 2049 dbSNP
rs935149130 2059 dbSNP
rs1210998228 2064 dbSNP
rs1294200228 2072 dbSNP
rs1020714138 2076 dbSNP
rs1257838098 2079 dbSNP
rs1306921460 2083 dbSNP
rs1296937410 2087 dbSNP
rs1216785818 2088 dbSNP
rs530217400 2090 dbSNP
rs1302968987 2091 dbSNP
rs1405912226 2092 dbSNP
rs542539241 2093 dbSNP
rs944877111 2094 dbSNP
rs1181815206 2095 dbSNP
rs1040505149 2096 dbSNP
rs1253118885 2098 dbSNP
rs893696338 2102 dbSNP
rs1430276953 2105 dbSNP
rs1427083496 2108 dbSNP
rs1473803763 2111 dbSNP
rs1010851787 2114 dbSNP
rs1198495748 2116 dbSNP
rs1050346021 2117 dbSNP
rs563818457 2119 dbSNP
rs1480637285 2120 dbSNP
rs889082341 2121 dbSNP
rs1008910741 2130 dbSNP
rs1251925046 2131 dbSNP
rs1019032232 2137 dbSNP
rs1410854688 2142 dbSNP
rs369353481 2144 dbSNP
rs1283192947 2145 dbSNP
rs1224582394 2150 dbSNP
rs1347706718 2151 dbSNP
rs552155588 2157 dbSNP
rs1389277680 2162 dbSNP
rs1372114636 2164 dbSNP
rs752020902 2166 dbSNP
rs1298299145 2168 dbSNP
rs1055101799 2169 dbSNP
rs1177708619 2175 dbSNP
rs1463056722 2178 dbSNP
rs994057173 2183 dbSNP
rs556030929 2184 dbSNP
rs1470135004 2185 dbSNP
rs1010502453 2192 dbSNP
rs1023351233 2193 dbSNP
rs1135845 2195 dbSNP
rs1465070967 2199 dbSNP
rs1418764398 2200 dbSNP
rs1251489453 2204 dbSNP
rs1298722792 2205 dbSNP
rs1460036711 2212 dbSNP
rs1263071669 2214 dbSNP
rs1000951621 2215 dbSNP
rs904913507 2218 dbSNP
rs1326136625 2221 dbSNP
rs1266665696 2224 dbSNP
rs566268500 2225 dbSNP
rs373085152 2230 dbSNP
rs535387815 2232 dbSNP
rs1034895471 2234 dbSNP
rs1287488263 2235 dbSNP
rs1345836093 2236 dbSNP
rs189627242 2243 dbSNP
rs1156646886 2244 dbSNP
rs62446366 2248 dbSNP
rs1452774005 2249 dbSNP
rs1470020200 2249 dbSNP
rs770112913 2249 dbSNP
rs77257221 2249 dbSNP
rs75433362 2250 dbSNP
rs528576378 2251 dbSNP
rs879201821 2254 dbSNP
rs1184250168 2256 dbSNP
rs1463085171 2259 dbSNP
rs916164704 2262 dbSNP
rs968991292 2263 dbSNP
rs1241804870 2264 dbSNP
rs1356685015 2265 dbSNP
rs1313791781 2266 dbSNP
rs1246046084 2270 dbSNP
rs981774938 2282 dbSNP
rs1316130054 2284 dbSNP
rs1027548852 2289 dbSNP
rs1385334138 2295 dbSNP
rs927714835 2297 dbSNP
rs1290881320 2301 dbSNP
rs1423015076 2303 dbSNP
rs935118573 2305 dbSNP
rs546670301 2307 dbSNP
rs577595953 2320 dbSNP
rs1164356333 2321 dbSNP
rs1446515143 2324 dbSNP
rs879075142 2330 dbSNP
rs1371851138 2331 dbSNP
rs1484320002 2339 dbSNP
rs952038075 2350 dbSNP
rs946546513 2352 dbSNP
rs536053143 2354 dbSNP
rs746563146 2356 dbSNP
rs1489748734 2358 dbSNP
rs1251557170 2361 dbSNP
rs889070911 2364 dbSNP
rs1290566025 2369 dbSNP
rs1222675321 2372 dbSNP
rs770299044 2379 dbSNP
rs1008900681 2380 dbSNP
rs966191121 2381 dbSNP
rs1478530820 2389 dbSNP
rs1040425099 2390 dbSNP
rs1297514011 2393 dbSNP
rs181155862 2394 dbSNP
rs568625656 2398 dbSNP
rs924830702 2400 dbSNP
rs934804028 2401 dbSNP
rs1422578986 2409 dbSNP
rs897893415 2427 dbSNP
rs1394361230 2428 dbSNP
rs1167875692 2431 dbSNP
rs1476050060 2432 dbSNP
rs1375266524 2437 dbSNP
rs993569534 2443 dbSNP
rs1480312961 2452 dbSNP
rs1168661121 2460 dbSNP
rs1028173805 2470 dbSNP
rs1054649971 2475 dbSNP
rs1452859535 2486 dbSNP
rs1270231023 2489 dbSNP
rs1194710636 2493 dbSNP
rs952206741 2499 dbSNP
rs946390003 2501 dbSNP
rs1013507855 2507 dbSNP
rs1803080 2511 dbSNP
rs1044750586 2512 dbSNP
rs1023164112 2519 dbSNP
rs35839545 2528 dbSNP
rs1350276612 2539 dbSNP
rs186183990 2551 dbSNP
rs1328330899 2557 dbSNP
rs35877514 2560 dbSNP
rs1056599418 2565 dbSNP
rs927662226 2570 dbSNP
rs1174824055 2573 dbSNP
rs1469625575 2580 dbSNP
rs1430363650 2581 dbSNP
rs1803079 2583 dbSNP
rs956586271 2588 dbSNP
rs987883265 2594 dbSNP
rs1365736508 2596 dbSNP
rs914983813 2599 dbSNP
rs34029691 2607 dbSNP
rs1050290715 2623 dbSNP
rs1344335598 2635 dbSNP
rs34755662 2638 dbSNP
rs1239950462 2641 dbSNP
rs36046982 2643 dbSNP
rs1452586966 2645 dbSNP
rs1322589858 2647 dbSNP
rs1224212078 2653 dbSNP
rs541163694 2656 dbSNP
rs897803721 2657 dbSNP
rs1348880413 2658 dbSNP
rs1279185310 2664 dbSNP
rs1443029908 2673 dbSNP
rs1379137686 2674 dbSNP
rs35464029 2675 dbSNP
rs1452502146 2679 dbSNP
rs1407443661 2683 dbSNP
rs1049108794 2684 dbSNP
rs138154471 2689 dbSNP
rs764277195 2697 dbSNP
rs542065419 2698 dbSNP
rs1470217470 2708 dbSNP
rs190750549 2714 dbSNP
rs575554072 2717 dbSNP
rs1167918422 2722 dbSNP
rs1032356977 2727 dbSNP
rs1414407231 2735 dbSNP
rs956366484 2747 dbSNP
rs1406933578 2749 dbSNP
rs1162427221 2750 dbSNP
rs988247786 2751 dbSNP
rs924664395 2754 dbSNP
rs1241613547 2755 dbSNP
rs1022043181 2757 dbSNP
rs1440461947 2763 dbSNP
rs968225491 2776 dbSNP
rs200200188 2780 dbSNP
rs746557156 2780 dbSNP
rs546051465 2784 dbSNP
rs1367475361 2786 dbSNP
rs181547861 2789 dbSNP
rs910360743 2812 dbSNP
rs112501768 2819 dbSNP
rs11400459 2819 dbSNP
rs397708823 2819 dbSNP
rs1357658781 2821 dbSNP
rs1230454894 2823 dbSNP
rs944543244 2824 dbSNP
rs1317252638 2825 dbSNP
rs1321442710 2826 dbSNP
rs975959446 2838 dbSNP
rs1419965899 2839 dbSNP
rs919174744 2847 dbSNP
rs540831608 2849 dbSNP
rs914741254 2852 dbSNP
rs929313522 2854 dbSNP
rs1049566369 2855 dbSNP
rs757369453 2859 dbSNP
rs61663251 2861 dbSNP
rs775252279 2863 dbSNP
rs1474330929 2866 dbSNP
rs1044615912 2868 dbSNP
rs887847764 2872 dbSNP
rs1289783958 2874 dbSNP
rs948834733 2878 dbSNP
rs1360245102 2883 dbSNP
rs1315498076 2886 dbSNP
rs1457534590 2888 dbSNP
rs1044472058 2891 dbSNP
rs186564580 2892 dbSNP
rs926333745 2899 dbSNP
rs938992433 2900 dbSNP
rs1056229196 2906 dbSNP
rs897535740 2910 dbSNP
rs993332439 2911 dbSNP
rs192097525 2914 dbSNP
rs1423514816 2917 dbSNP
rs1349932437 2918 dbSNP
rs1002997887 2926 dbSNP
rs1031916792 2927 dbSNP
rs1007509049 2929 dbSNP
rs1017512696 2937 dbSNP
rs892083288 2947 dbSNP
rs1009217488 2948 dbSNP
rs966088947 2949 dbSNP
rs1022408271 2952 dbSNP
rs967722154 2957 dbSNP
rs1267336823 2958 dbSNP
rs1202468137 2959 dbSNP
rs1307440122 2968 dbSNP
rs1450838113 2968 dbSNP
rs985856588 2971 dbSNP
rs1220920243 2975 dbSNP
rs1281033795 2980 dbSNP
rs562034618 2980 dbSNP
rs752808937 2993 dbSNP
rs115894490 2995 dbSNP
rs1328134003 3005 dbSNP
rs1229361892 3008 dbSNP
rs990188155 3013 dbSNP
rs1294793121 3014 dbSNP
rs1269685940 3019 dbSNP
rs1353937171 3026 dbSNP
rs1326634805 3031 dbSNP
rs1207636317 3036 dbSNP
rs975946288 3051 dbSNP
rs1171288996 3056 dbSNP
rs548088562 3056 dbSNP
rs1021777751 3058 dbSNP
rs970182577 3060 dbSNP
rs557043530 3062 dbSNP
rs1175396063 3064 dbSNP
rs1434007470 3072 dbSNP
rs919177479 3079 dbSNP
rs1175561483 3080 dbSNP
rs1480346310 3082 dbSNP
rs928852214 3084 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uugauAUGUUGGAGGAUGGAGu 5'
               |:|||||| ||||||| 
Target 5' cucacUGCAACCU-CUACCUCc 3'
9 - 29
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000242057.4 | 3UTR | AAUCUUGGCUCACUGCAACCUCUACCUCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP -0.595 0 -0.582 0 32 Click to see details
LIHC -0.297 0.02 -0.273 0.03 49 Click to see details
STAD -0.285 0.06 -0.286 0.06 32 Click to see details
ESCA -0.42 0.1 -0.127 0.35 11 Click to see details
PCPG 0.942 0.11 1.000 0.5 3 Click to see details
BLCA 0.302 0.11 0.304 0.11 18 Click to see details
THCA -0.136 0.15 -0.153 0.12 59 Click to see details
LUSC -0.156 0.17 -0.089 0.3 38 Click to see details
KICH -0.171 0.21 -0.105 0.31 25 Click to see details
CHOL -0.251 0.26 -0.200 0.3 9 Click to see details
KIRC -0.079 0.26 -0.069 0.29 68 Click to see details
BRCA -0.066 0.28 -0.112 0.16 84 Click to see details
LUAD 0.167 0.3 0.287 0.18 12 Click to see details
PAAD 0.376 0.31 0.200 0.4 4 Click to see details
CESC 0.478 0.34 0.500 0.33 3 Click to see details
HNSC 0.06 0.35 0.086 0.29 42 Click to see details
COAD -0.098 0.41 -0.262 0.27 8 Click to see details
UCEC -0.049 0.42 -0.160 0.26 19 Click to see details
PRAD -0.021 0.44 -0.012 0.47 50 Click to see details
PRAD -0.021 0.44 -0.012 0.47 50 Click to see details
PRAD -0.021 0.44 -0.012 0.47 50 Click to see details
581 hsa-let-7e-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT002081 HMGA2 high mobility group AT-hook 2 5 5
MIRT003932 EIF3J eukaryotic translation initiation factor 3 subunit J 2 1
MIRT004469 SMC1A structural maintenance of chromosomes 1A 4 7
MIRT005718 WNT1 Wnt family member 1 4 1
MIRT006122 CCND1 cyclin D1 5 4
MIRT006404 MPL MPL proto-oncogene, thrombopoietin receptor 1 1
MIRT032098 RABGAP1L RAB GTPase activating protein 1 like 1 1
MIRT032099 DAD1 defender against cell death 1 1 1
MIRT032100 MYCN MYCN proto-oncogene, bHLH transcription factor 4 2
MIRT051413 WDR67 TBC1 domain family member 31 1 1
MIRT051414 FAM219B family with sequence similarity 219 member B 1 1
MIRT051415 C11orf91 chromosome 11 open reading frame 91 1 1
MIRT051416 CENPP centromere protein P 1 1
MIRT051417 TMEM107 transmembrane protein 107 1 1
MIRT051418 SREBF1 sterol regulatory element binding transcription factor 1 1 1
MIRT051419 DAAM1 dishevelled associated activator of morphogenesis 1 1 1
MIRT051420 DGCR8 DGCR8, microprocessor complex subunit 1 1
MIRT051421 RAP1A RAP1A, member of RAS oncogene family 1 1
MIRT051422 RPA1 replication protein A1 1 1
MIRT051423 SKIV2L Ski2 like RNA helicase 1 1
MIRT051424 AGO1 argonaute 1, RISC catalytic component 4 2
MIRT051425 RPS27 ribosomal protein S27 1 1
MIRT051426 ARNT2 aryl hydrocarbon receptor nuclear translocator 2 1 1
MIRT051427 GPM6B glycoprotein M6B 1 1
MIRT051428 TTLL12 tubulin tyrosine ligase like 12 1 1
MIRT051429 HIST2H2BF histone cluster 2 H2B family member f 1 1
MIRT051430 CELF2 CUGBP Elav-like family member 2 1 1
MIRT051431 AGO2 argonaute 2, RISC catalytic component 1 1
MIRT051432 VPS13D vacuolar protein sorting 13 homolog D 1 1
MIRT051433 RPL10 ribosomal protein L10 1 1
MIRT051434 SPCS2 signal peptidase complex subunit 2 1 1
MIRT051435 DCAF8 DDB1 and CUL4 associated factor 8 1 1
MIRT051436 CTC1 CST telomere replication complex component 1 1 1
MIRT051437 NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1 1
MIRT051438 PHF3 PHD finger protein 3 1 1
MIRT051439 TUBA1B tubulin alpha 1b 1 1
MIRT051440 SHANK1 SH3 and multiple ankyrin repeat domains 1 1 1
MIRT051441 SKA2 spindle and kinetochore associated complex subunit 2 1 1
MIRT051442 SPTBN1 spectrin beta, non-erythrocytic 1 1 1
MIRT051443 ND2 MTND2 1 1
MIRT051444 MED13L mediator complex subunit 13 like 1 1
MIRT051445 RCOR3 REST corepressor 3 1 1
MIRT051446 MACF1 microtubule-actin crosslinking factor 1 1 1
MIRT051447 RDX radixin 2 5
MIRT051448 PCBP2 poly(rC) binding protein 2 1 1
MIRT051449 UBAP2L ubiquitin associated protein 2 like 1 1
MIRT051450 CDCA3 cell division cycle associated 3 1 1
MIRT051451 CABLES1 Cdk5 and Abl enzyme substrate 1 1 1
MIRT051452 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1 1
MIRT051453 C12orf49 chromosome 12 open reading frame 49 1 1
MIRT051454 TIMP3 TIMP metallopeptidase inhibitor 3 1 1
MIRT051455 WBSCR16 RCC1 like 1 1
MIRT051456 SLC2A11 solute carrier family 2 member 11 1 1
MIRT051457 NF1 neurofibromin 1 1 1
MIRT051458 LRRC8A leucine rich repeat containing 8 VRAC subunit A 1 1
MIRT051459 RUNX1T1 RUNX1 translocation partner 1 1 1
MIRT051460 DTNB dystrobrevin beta 1 1
MIRT051461 SCMH1 Scm polycomb group protein homolog 1 1 1
MIRT051462 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma 1 1
MIRT051463 RHBDD2 rhomboid domain containing 2 1 1
MIRT051464 ND5 NADH dehydrogenase, subunit 5 (complex I) 1 1
MIRT051465 NDST1 N-deacetylase and N-sulfotransferase 1 1 1
MIRT051466 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 5
MIRT051467 EIF4A1 eukaryotic translation initiation factor 4A1 1 1
MIRT051468 BAHCC1 BAH domain and coiled-coil containing 1 1 1
MIRT051469 CARM1 coactivator associated arginine methyltransferase 1 1 1
MIRT051470 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 1 1
MIRT051471 ND3 NADH dehydrogenase, subunit 3 (complex I) 1 1
MIRT051472 PIGS phosphatidylinositol glycan anchor biosynthesis class S 1 1
MIRT051473 ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1 1
MIRT051474 RPN2 ribophorin II 1 1
MIRT051475 RPL12 ribosomal protein L12 1 1
MIRT051476 NME4 NME/NM23 nucleoside diphosphate kinase 4 1 1
MIRT051477 IVD isovaleryl-CoA dehydrogenase 1 1
MIRT051478 JAZF1 JAZF zinc finger 1 1 1
MIRT051479 ND4 NADH dehydrogenase, subunit 4 (complex I) 1 1
MIRT051480 VARS valyl-tRNA synthetase 1 1
MIRT051481 RNF26 ring finger protein 26 1 1
MIRT051482 LHFPL2 LHFPL tetraspan subfamily member 2 1 1
MIRT051483 ARCN1 archain 1 1 1
MIRT051484 COX1 cytochrome c oxidase subunit I 1 1
MIRT051485 SLC12A4 solute carrier family 12 member 4 1 1
MIRT051486 AEBP2 AE binding protein 2 1 1
MIRT051487 PET112 glutamyl-tRNA amidotransferase subunit B 1 1
MIRT051488 UROC1 urocanate hydratase 1 1 1
MIRT051489 IGF1R insulin like growth factor 1 receptor 5 10
MIRT051490 BSDC1 BSD domain containing 1 1 1
MIRT051491 PTK2 protein tyrosine kinase 2 1 1
MIRT051492 CDC5L cell division cycle 5 like 1 1
MIRT051493 EN2 engrailed homeobox 2 1 1
MIRT051494 SSB Sjogren syndrome antigen B 1 1
MIRT051495 SLCO3A1 solute carrier organic anion transporter family member 3A1 1 1
MIRT051496 RRAGC Ras related GTP binding C 1 1
MIRT051497 ZNF236 zinc finger protein 236 1 1
MIRT051498 SEMA4B semaphorin 4B 1 1
MIRT051499 SERBP1 SERPINE1 mRNA binding protein 1 1 1
MIRT051500 XIAP X-linked inhibitor of apoptosis 1 1
MIRT051501 GTF2I general transcription factor IIi 1 1
MIRT051502 JMJD1C jumonji domain containing 1C 1 1
MIRT051503 OTUD5 OTU deubiquitinase 5 1 1
MIRT051504 NOLC1 nucleolar and coiled-body phosphoprotein 1 1 1
MIRT051505 PPIG peptidylprolyl isomerase G 1 1
MIRT051506 PSMD2 proteasome 26S subunit, non-ATPase 2 1 1
MIRT051507 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1 1
MIRT051508 VAMP2 vesicle associated membrane protein 2 1 1
MIRT051509 LSR lipolysis stimulated lipoprotein receptor 1 1
MIRT051510 KIAA0355 KIAA0355 1 1
MIRT051511 RPSA ribosomal protein SA 1 1
MIRT051512 DCAF6 DDB1 and CUL4 associated factor 6 1 1
MIRT051513 UHRF1BP1 UHRF1 binding protein 1 1 1
MIRT051514 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1 1
MIRT051515 PIGP phosphatidylinositol glycan anchor biosynthesis class P 1 1
MIRT051516 LMLN leishmanolysin like peptidase 1 1
MIRT051517 PPP2R1A protein phosphatase 2 scaffold subunit Aalpha 1 1
MIRT051518 HIPK1 homeodomain interacting protein kinase 1 1 1
MIRT051519 SERF2 small EDRK-rich factor 2 1 1
MIRT051520 RBM4 RNA binding motif protein 4 1 1
MIRT051521 RBM14 RNA binding motif protein 14 1 1
MIRT051522 HMGB1 high mobility group box 1 1 1
MIRT051523 GMPS guanine monophosphate synthase 1 1
MIRT051524 DIAPH1 diaphanous related formin 1 1 1
MIRT051525 STAM signal transducing adaptor molecule 1 1
MIRT051526 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 1 1
MIRT051527 APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 1 1
MIRT051528 MARCH5 membrane associated ring-CH-type finger 5 1 1
MIRT051529 SQLE squalene epoxidase 1 1
MIRT051530 TIMM50 translocase of inner mitochondrial membrane 50 1 1
MIRT051531 NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 1 1
MIRT051532 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 1 1
MIRT051533 NRSN2 neurensin 2 1 1
MIRT051534 SALL1 spalt like transcription factor 1 1 1
MIRT051535 COX3 cytochrome c oxidase III 1 1
MIRT051536 RABL6 RAB, member RAS oncogene family like 6 1 1
MIRT051537 SUPT4H1 SPT4 homolog, DSIF elongation factor subunit 1 1
MIRT051538 PACS2 phosphofurin acidic cluster sorting protein 2 1 1
MIRT051539 MTMR14 myotubularin related protein 14 1 1
MIRT051540 LUZP1 leucine zipper protein 1 1 1
MIRT051541 PFAS phosphoribosylformylglycinamidine synthase 1 1
MIRT051542 SUZ12 SUZ12 polycomb repressive complex 2 subunit 1 1
MIRT051543 PAPD4 poly(A) RNA polymerase D4, non-canonical 1 1
MIRT051544 QSOX1 quiescin sulfhydryl oxidase 1 1 1
MIRT051545 SPATA13 spermatogenesis associated 13 1 1
MIRT051546 DHX57 DExH-box helicase 57 1 1
MIRT051547 KATNB1 katanin regulatory subunit B1 1 1
MIRT051548 COL6A1 collagen type VI alpha 1 chain 1 1
MIRT051549 DHX15 DEAH-box helicase 15 1 1
MIRT051550 MTCH2 mitochondrial carrier 2 1 1
MIRT051551 KIAA0100 KIAA0100 1 1
MIRT051552 SUGP2 SURP and G-patch domain containing 2 1 1
MIRT051553 NCLN nicalin 1 1
MIRT051554 ATXN2L ataxin 2 like 1 1
MIRT051555 CHD9 chromodomain helicase DNA binding protein 9 1 1
MIRT051556 PES1 pescadillo ribosomal biogenesis factor 1 1 1
MIRT051557 NUP155 nucleoporin 155 2 7
MIRT051558 GNG5 G protein subunit gamma 5 2 3
MIRT051559 ARHGAP19 Rho GTPase activating protein 19 1 1
MIRT051560 MTFR1 mitochondrial fission regulator 1 1 1
MIRT051561 IRS2 insulin receptor substrate 2 2 1
MIRT051562 IRS4 insulin receptor substrate 4 1 1
MIRT051563 PPP1R10 protein phosphatase 1 regulatory subunit 10 1 1
MIRT051564 ZNF284 zinc finger protein 284 1 1
MIRT051565 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 1 1
MIRT051566 SCD stearoyl-CoA desaturase 1 1
MIRT051567 FDPS farnesyl diphosphate synthase 1 1
MIRT051568 KRBOX4 KRAB box domain containing 4 1 1
MIRT051569 BRI3 brain protein I3 1 1
MIRT051570 CHD7 chromodomain helicase DNA binding protein 7 1 1
MIRT051571 PYCR1 pyrroline-5-carboxylate reductase 1 1 1
MIRT051572 SMAP2 small ArfGAP2 1 1
MIRT051573 WDFY3 WD repeat and FYVE domain containing 3 1 1
MIRT051574 CRK CRK proto-oncogene, adaptor protein 1 1
MIRT051575 SRSF2 serine and arginine rich splicing factor 2 1 1
MIRT051576 PGD phosphogluconate dehydrogenase 1 1
MIRT051577 RMND5A required for meiotic nuclear division 5 homolog A 1 1
MIRT051578 ZNF652 zinc finger protein 652 1 1
MIRT051579 PSMA6 proteasome subunit alpha 6 1 1
MIRT051580 SLC38A2 solute carrier family 38 member 2 1 1
MIRT051581 LRRC41 leucine rich repeat containing 41 1 1
MIRT051582 RANBP2 RAN binding protein 2 1 1
MIRT051583 SVIL supervillin 1 1
MIRT051584 CCNG1 cyclin G1 1 1
MIRT051585 ZNF256 zinc finger protein 256 1 1
MIRT051586 COPG1 coatomer protein complex subunit gamma 1 1 1
MIRT051587 PDCD11 programmed cell death 11 1 1
MIRT051588 CNBP CCHC-type zinc finger nucleic acid binding protein 1 1
MIRT051589 USP37 ubiquitin specific peptidase 37 1 1
MIRT051590 UBE2V2 ubiquitin conjugating enzyme E2 V2 1 1
MIRT051591 UBE2H ubiquitin conjugating enzyme E2 H 1 1
MIRT051592 LMNA lamin A/C 1 1
MIRT051593 STAT3 signal transducer and activator of transcription 3 1 1
MIRT051594 TRPV1 transient receptor potential cation channel subfamily V member 1 1 1
MIRT051595 MATR3 matrin 3 1 1
MIRT051596 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1 1
MIRT051597 HS6ST2 heparan sulfate 6-O-sulfotransferase 2 1 1
MIRT051598 WDR48 WD repeat domain 48 1 1
MIRT051599 RBM8A RNA binding motif protein 8A 1 1
MIRT051600 SCYL1 SCY1 like pseudokinase 1 1 1
MIRT051601 C19orf48 chromosome 19 open reading frame 48 1 1
MIRT051602 FOXD4L6 forkhead box D4 like 6 1 1
MIRT051603 PIGN phosphatidylinositol glycan anchor biosynthesis class N 1 1
MIRT051604 SPCS3 signal peptidase complex subunit 3 1 1
MIRT051605 TNFAIP1 TNF alpha induced protein 1 1 1
MIRT051606 MS4A10 membrane spanning 4-domains A10 1 1
MIRT051607 MSMO1 methylsterol monooxygenase 1 1 1
MIRT051608 ARID1A AT-rich interaction domain 1A 1 1
MIRT051609 NCKIPSD NCK interacting protein with SH3 domain 2 5
MIRT051610 NCBP1 nuclear cap binding protein subunit 1 1 1
MIRT051611 COX16 COX16, cytochrome c oxidase assembly homolog 1 1
MIRT051612 NUDT8 nudix hydrolase 8 1 1
MIRT051613 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT051614 TXNRD1 thioredoxin reductase 1 1 1
MIRT051615 ELMSAN1 ELM2 and Myb/SANT domain containing 1 1 1
MIRT051616 CTSA cathepsin A 1 1
MIRT051617 PRRC2A proline rich coiled-coil 2A 1 1
MIRT051618 SPAG9 sperm associated antigen 9 1 1
MIRT051619 AGMAT agmatinase 1 1
MIRT051620 NCKAP5L NCK associated protein 5 like 1 1
MIRT051621 ZFP62 ZFP62 zinc finger protein 1 1
MIRT051622 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1 1
MIRT051623 POLR3D RNA polymerase III subunit D 2 3
MIRT051624 PRPF8 pre-mRNA processing factor 8 1 1
MIRT051625 ATP6 ATP synthase F0 subunit 6 1 1
MIRT051626 ZFAND5 zinc finger AN1-type containing 5 1 1
MIRT051627 BAZ1B bromodomain adjacent to zinc finger domain 1B 1 1
MIRT051628 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT051629 BMP2K BMP2 inducible kinase 1 1
MIRT051630 SPN sialophorin 1 1
MIRT051631 PA2G4 proliferation-associated 2G4 1 1
MIRT051632 RPRD2 regulation of nuclear pre-mRNA domain containing 2 1 1
MIRT051633 TUBB4B tubulin beta 4B class IVb 1 1
MIRT051634 TRRAP transformation/transcription domain associated protein 1 1
MIRT051635 SLCO4A1 solute carrier organic anion transporter family member 4A1 1 1
MIRT051636 CCRN4L nocturnin 1 1
MIRT051637 USE1 unconventional SNARE in the ER 1 1 1
MIRT051638 STARD7 StAR related lipid transfer domain containing 7 1 1
MIRT051639 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 3
MIRT051640 CLTC clathrin heavy chain 1 1
MIRT051641 TERF1 telomeric repeat binding factor 1 1 1
MIRT051642 PAX3 paired box 3 1 1
MIRT051643 CCDC97 coiled-coil domain containing 97 1 1
MIRT051644 HLA-C major histocompatibility complex, class I, C 1 1
MIRT051645 GTPBP8 GTP binding protein 8 (putative) 1 1
MIRT051646 VGLL4 vestigial like family member 4 1 1
MIRT051647 ANKRD40 ankyrin repeat domain 40 1 1
MIRT051648 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 1 1
MIRT051649 ND1 NADH dehydrogenase, subunit 1 (complex I) 1 1
MIRT051650 DSP desmoplakin 1 1
MIRT051651 UBN2 ubinuclein 2 1 1
MIRT051652 ZNF805 zinc finger protein 805 1 1
MIRT051653 RBBP4 RB binding protein 4, chromatin remodeling factor 1 1
MIRT051654 OCLN occludin 1 1
MIRT051655 CBX5 chromobox 5 2 3
MIRT051656 AMPD2 adenosine monophosphate deaminase 2 1 1
MIRT051657 MKI67 marker of proliferation Ki-67 1 1
MIRT051658 SUB1 SUB1 homolog, transcriptional regulator 1 1
MIRT051659 RSL1D1 ribosomal L1 domain containing 1 1 1
MIRT051660 SEC23IP SEC23 interacting protein 1 1
MIRT051661 RNMT RNA guanine-7 methyltransferase 1 1
MIRT051662 SGSM3 small G protein signaling modulator 3 1 1
MIRT051663 ZFP3 ZFP3 zinc finger protein 1 1
MIRT051664 GLUL glutamate-ammonia ligase 1 1
MIRT051665 POLD1 DNA polymerase delta 1, catalytic subunit 1 1
MIRT051666 WDR4 WD repeat domain 4 1 1
MIRT051667 PPP1R2 protein phosphatase 1 regulatory inhibitor subunit 2 1 1
MIRT051668 RAI2 retinoic acid induced 2 1 1
MIRT051669 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 1 1
MIRT051670 UTP15 UTP15, small subunit processome component 1 1
MIRT051671 THADA THADA, armadillo repeat containing 1 1
MIRT051672 ZNF451 zinc finger protein 451 1 1
MIRT051673 CREBBP CREB binding protein 1 1
MIRT051674 ZNF770 zinc finger protein 770 1 1
MIRT051675 CLDN4 claudin 4 1 1
MIRT051676 ZKSCAN7 zinc finger with KRAB and SCAN domains 7 1 1
MIRT051677 NICN1 nicolin 1 1 1
MIRT051678 RPLP2 ribosomal protein lateral stalk subunit P2 1 1
MIRT051679 DCBLD2 discoidin, CUB and LCCL domain containing 2 1 1
MIRT051680 IRGQ immunity related GTPase Q 1 1
MIRT051681 CA5B carbonic anhydrase 5B 1 1
MIRT051682 COX14 COX14, cytochrome c oxidase assembly factor 1 1
MIRT051683 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT051684 RPL27A ribosomal protein L27a 1 1
MIRT051685 CWC15 CWC15 spliceosome associated protein homolog 1 1
MIRT051686 NT5DC2 5'-nucleotidase domain containing 2 1 1
MIRT051687 OR7D2 olfactory receptor family 7 subfamily D member 2 1 1
MIRT051688 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 1 1
MIRT051689 NUDT15 nudix hydrolase 15 1 1
MIRT051690 CDH18 cadherin 18 1 1
MIRT051691 FAM160B1 family with sequence similarity 160 member B1 1 1
MIRT051692 DZIP1 DAZ interacting zinc finger protein 1 1 1
MIRT051693 TDRD7 tudor domain containing 7 1 1
MIRT051694 TCF4 transcription factor 4 1 1
MIRT051695 ENSA endosulfine alpha 1 1
MIRT051696 GTF3C1 general transcription factor IIIC subunit 1 1 1
MIRT051697 TNFRSF1A TNF receptor superfamily member 1A 1 1
MIRT051698 CCDC113 coiled-coil domain containing 113 1 1
MIRT051699 MYO9B myosin IXB 1 1
MIRT051700 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 1 1
MIRT051701 PRAMEF13 PRAME family member 13 1 1
MIRT051702 PMPCA peptidase, mitochondrial processing alpha subunit 2 5
MIRT051703 MRPS2 mitochondrial ribosomal protein S2 1 1
MIRT051704 RACGAP1 Rac GTPase activating protein 1 1 1
MIRT051705 CCDC106 coiled-coil domain containing 106 1 1
MIRT051706 CYP2B6 cytochrome P450 family 2 subfamily B member 6 1 1
MIRT051707 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 3
MIRT051708 PSME4 proteasome activator subunit 4 1 1
MIRT051709 SETD1A SET domain containing 1A 1 1
MIRT054561 MMP9 matrix metallopeptidase 9 3 1
MIRT054579 IGF1 insulin like growth factor 1 3 1
MIRT063195 ADIPOR2 adiponectin receptor 2 2 2
MIRT065687 ESPL1 extra spindle pole bodies like 1, separase 2 4
MIRT067399 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT068154 TXLNA taxilin alpha 2 2
MIRT068528 NHLRC3 NHL repeat containing 3 2 6
MIRT068789 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT073006 ARID3B AT-rich interaction domain 3B 2 6
MIRT076223 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT077616 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT080398 ONECUT2 one cut homeobox 2 2 2
MIRT083300 ZCCHC3 zinc finger CCHC-type containing 3 2 2
MIRT084976 BACH1 BTB domain and CNC homolog 1 2 2
MIRT094160 PCGF3 polycomb group ring finger 3 2 6
MIRT094460 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 4
MIRT095766 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT100094 ABT1 activator of basal transcription 1 2 8
MIRT112242 MDM4 MDM4, p53 regulator 2 4
MIRT118586 STK4 serine/threonine kinase 4 2 2
MIRT120921 PDE12 phosphodiesterase 12 2 8
MIRT123317 CALU calumenin 2 2
MIRT152272 TNFSF9 TNF superfamily member 9 2 2
MIRT153847 NCOA3 nuclear receptor coactivator 3 2 2
MIRT168583 HMGA1 high mobility group AT-hook 1 2 4
MIRT180603 CRY2 cryptochrome circadian clock 2 2 2
MIRT187717 SUOX sulfite oxidase 2 2
MIRT191404 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT193101 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT215720 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT218815 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT240330 UBXN2B UBX domain protein 2B 2 2
MIRT243473 TRIM71 tripartite motif containing 71 2 2
MIRT244069 EDN1 endothelin 1 2 2
MIRT252330 SALL3 spalt like transcription factor 3 2 2
MIRT255314 CDV3 CDV3 homolog 2 2
MIRT259277 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT259479 TXLNG taxilin gamma 2 2
MIRT260707 CLDN12 claudin 12 2 6
MIRT264693 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT266212 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT266626 CHTOP chromatin target of PRMT1 2 2
MIRT268839 C1ORF21 chromosome 1 open reading frame 21 2 2
MIRT294446 ZNF264 zinc finger protein 264 2 2
MIRT297013 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT297443 SLC20A1 solute carrier family 20 member 1 2 4
MIRT300037 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT300893 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT303320 MXD1 MAX dimerization protein 1 2 2
MIRT309846 NAT8L N-acetyltransferase 8 like 2 2
MIRT322428 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT324731 ACER2 alkaline ceramidase 2 2 2
MIRT402057 ATP6V1F ATPase H+ transporting V1 subunit F 2 4
MIRT437395 LIN28A lin-28 homolog A 4 1
MIRT437396 AURKB aurora kinase B 4 1
MIRT437435 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2 1
MIRT438632 TNFRSF10B TNF receptor superfamily member 10b 2 1
MIRT439135 MYC MYC proto-oncogene, bHLH transcription factor 0 1
MIRT442020 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT445658 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT447136 KIF27 kinesin family member 27 2 2
MIRT448259 ZNF774 zinc finger protein 774 2 2
MIRT449005 ANKRD46 ankyrin repeat domain 46 2 2
MIRT449953 FMNL3 formin like 3 2 2
MIRT451155 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT451624 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT451693 C1RL complement C1r subcomponent like 2 2
MIRT452092 NUCB2 nucleobindin 2 2 2
MIRT452431 QDPR quinoid dihydropteridine reductase 2 2
MIRT452943 DISC1 disrupted in schizophrenia 1 2 2
MIRT453401 RHD Rh blood group D antigen 2 6
MIRT454164 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT454280 FXN frataxin 2 2
MIRT454539 RABL2A RAB, member of RAS oncogene family like 2A 2 2
MIRT454854 ACOT9 acyl-CoA thioesterase 9 2 4
MIRT455676 GLO1 glyoxalase I 2 2
MIRT457248 RABL2B RAB, member of RAS oncogene family like 2B 2 2
MIRT457677 ZNF587 zinc finger protein 587 2 2
MIRT457887 THEM6 thioesterase superfamily member 6 2 4
MIRT458016 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458279 FUT10 fucosyltransferase 10 2 2
MIRT459736 RRM1 ribonucleotide reductase catalytic subunit M1 2 2
MIRT460453 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460500 FAM105A family with sequence similarity 105 member A 2 6
MIRT460938 NOA1 nitric oxide associated 1 2 4
MIRT461092 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461169 SLC11A2 solute carrier family 11 member 2 2 4
MIRT461364 COL8A1 collagen type VIII alpha 1 chain 2 2
MIRT462382 YAE1D1 Yae1 domain containing 1 2 2
MIRT462780 ZNF8 zinc finger protein 8 2 2
MIRT463420 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463662 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464265 VCL vinculin 2 2
MIRT465122 TSC22D2 TSC22 domain family member 2 2 4
MIRT466184 TMED5 transmembrane p24 trafficking protein 5 2 4
MIRT466722 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT469102 RNF144B ring finger protein 144B 2 2
MIRT469714 RAB40C RAB40C, member RAS oncogene family 2 2
MIRT470425 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT470679 POLR2D RNA polymerase II subunit D 2 4
MIRT470861 PLXND1 plexin D1 2 2
MIRT471271 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471957 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472672 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2 2
MIRT472739 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT473134 MLLT10 MLLT10, histone lysine methyltransferase DOT1L cofactor 2 2
MIRT473234 SMCR7L mitochondrial elongation factor 1 1 4
MIRT473828 MAP2K7 mitogen-activated protein kinase kinase 7 2 2
MIRT473940 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT474022 LRRC20 leucine rich repeat containing 20 2 2
MIRT474502 KLHDC8B kelch domain containing 8B 2 2
MIRT474766 KIAA0930 KIAA0930 2 2
MIRT474905 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475331 IFNLR1 interferon lambda receptor 1 2 2
MIRT475379 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475733 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT476548 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT476973 FAM83G family with sequence similarity 83 member G 2 4
MIRT477534 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 2 4
MIRT477682 EFHD2 EF-hand domain family member D2 2 2
MIRT481201 ATXN7L3B ataxin 7 like 3B 2 4
MIRT481241 ATXN7L3 ataxin 7 like 3 2 2
MIRT481363 ATG9A autophagy related 9A 2 2
MIRT481388 ATG12 autophagy related 12 2 2
MIRT481652 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT481851 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT482184 AHR aryl hydrocarbon receptor 2 2
MIRT482220 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT485296 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT486659 ZNF28 zinc finger protein 28 2 2
MIRT489413 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491867 ZBTB5 zinc finger and BTB domain containing 5 2 8
MIRT492216 SOCS1 suppressor of cytokine signaling 1 2 2
MIRT492626 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT493323 LIMD2 LIM domain containing 2 2 2
MIRT493901 FAM43A family with sequence similarity 43 member A 2 4
MIRT494263 CEP120 centrosomal protein 120 2 2
MIRT494687 ARID3A AT-rich interaction domain 3A 2 2
MIRT495968 TBC1D19 TBC1 domain family member 19 2 2
MIRT496111 SNX17 sorting nexin 17 2 2
MIRT497875 SLC12A7 solute carrier family 12 member 7 2 2
MIRT498122 PLEKHO1 pleckstrin homology domain containing O1 2 4
MIRT499405 PLCG2 phospholipase C gamma 2 2 4
MIRT499493 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 2 2
MIRT499653 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT499942 MFSD8 major facilitator superfamily domain containing 8 2 2
MIRT499997 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT500819 THBS1 thrombospondin 1 2 3
MIRT500902 STRN striatin 2 4
MIRT501118 SLC5A6 solute carrier family 5 member 6 2 4
MIRT501173 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501202 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT501241 SEMA4C semaphorin 4C 2 6
MIRT501328 RNFT1 ring finger protein, transmembrane 1 2 2
MIRT501355 RNF44 ring finger protein 44 2 4
MIRT501387 RBFOX2 RNA binding protein, fox-1 homolog 2 2 10
MIRT501441 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501759 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT501943 MBD2 methyl-CpG binding domain protein 2 2 8
MIRT502106 KPNA5 karyopherin subunit alpha 5 2 8
MIRT502130 KMT2D lysine methyltransferase 2D 2 4
MIRT502784 CEP135 centrosomal protein 135 2 2
MIRT502845 CELF1 CUGBP Elav-like family member 1 2 2
MIRT504789 C12orf4 chromosome 12 open reading frame 4 2 2
MIRT505017 ZNF644 zinc finger protein 644 2 2
MIRT506942 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507252 FIGN fidgetin, microtubule severing factor 2 8
MIRT507694 COIL coilin 2 6
MIRT508401 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508665 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT508932 AK4 adenylate kinase 4 2 4
MIRT510395 ZNF566 zinc finger protein 566 2 6
MIRT510518 YOD1 YOD1 deubiquitinase 2 6
MIRT511386 IKZF3 IKAROS family zinc finger 3 2 4
MIRT512745 CD59 CD59 molecule (CD59 blood group) 2 4
MIRT515954 C9orf156 tRNA methyltransferase O 2 2
MIRT516083 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT523619 FZD9 frizzled class receptor 9 2 4
MIRT523733 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523990 DVL3 dishevelled segment polarity protein 3 2 2
MIRT524113 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT525727 SOD2 superoxide dismutase 2 2 2
MIRT527763 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT529727 OPRL1 opioid related nociceptin receptor 1 2 2
MIRT533187 WASL Wiskott-Aldrich syndrome like 2 6
MIRT536378 LEFTY1 left-right determination factor 1 2 2
MIRT543785 RBM12B RNA binding motif protein 12B 2 4
MIRT543868 SLC16A9 solute carrier family 16 member 9 2 2
MIRT545387 PM20D2 peptidase M20 domain containing 2 2 2
MIRT545890 ZNF200 zinc finger protein 200 2 4
MIRT546334 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT547373 MSI2 musashi RNA binding protein 2 2 2
MIRT547579 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548264 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT548351 EPHA4 EPH receptor A4 2 2
MIRT548534 DUSP1 dual specificity phosphatase 1 2 2
MIRT548560 DNAL1 dynein axonemal light chain 1 2 2
MIRT548779 COLEC12 collectin subfamily member 12 2 2
MIRT548978 CCNT2 cyclin T2 2 2
MIRT549208 BEND4 BEN domain containing 4 2 4
MIRT549763 ZNF611 zinc finger protein 611 2 6
MIRT549799 KIAA0391 KIAA0391 2 2
MIRT549847 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT550898 ACTA1 actin, alpha 1, skeletal muscle 2 2
MIRT551283 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551318 GSG2 histone H3 associated protein kinase 2 6
MIRT551932 AKAP8 A-kinase anchoring protein 8 2 4
MIRT552003 RAD18 RAD18, E3 ubiquitin protein ligase 2 2
MIRT552410 ZNF460 zinc finger protein 460 2 4
MIRT553013 USP38 ubiquitin specific peptidase 38 2 2
MIRT555550 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT555711 PDZD8 PDZ domain containing 8 2 2
MIRT557372 HAND1 heart and neural crest derivatives expressed 1 2 2
MIRT557960 FAM222B family with sequence similarity 222 member B 2 2
MIRT559087 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559497 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT561772 PEG10 paternally expressed 10 2 2
MIRT564402 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT565443 SURF4 surfeit 4 2 2
MIRT566518 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT567715 E2F6 E2F transcription factor 6 2 2
MIRT568655 ABHD17C abhydrolase domain containing 17C 2 2
MIRT569498 THYN1 thymocyte nuclear protein 1 2 2
MIRT573820 TGOLN2 trans-golgi network protein 2 2 2
MIRT574363 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT574750 GOLGA4 golgin A4 2 2
MIRT574788 FAM104A family with sequence similarity 104 member A 2 2
MIRT576089 Poteg POTE ankyrin domain family, member G 2 2
MIRT576812 Thbs1 thrombospondin 1 2 3
MIRT616370 RWDD1 RWD domain containing 1 2 2
MIRT617851 FMO4 flavin containing monooxygenase 4 2 2
MIRT642394 ZNF556 zinc finger protein 556 2 2
MIRT680519 PRIM2 DNA primase subunit 2 2 2
MIRT680547 ZNF584 zinc finger protein 584 2 2
MIRT680800 ZNF578 zinc finger protein 578 2 2
MIRT680838 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT681141 INTS7 integrator complex subunit 7 2 2
MIRT681271 RFC2 replication factor C subunit 2 2 2
MIRT681323 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT681359 BRI3BP BRI3 binding protein 2 2
MIRT681506 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681536 ZNF738 zinc finger protein 738 2 2
MIRT681658 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT681738 RAB19 RAB19, member RAS oncogene family 2 4
MIRT681797 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681869 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT681941 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682102 ITGA3 integrin subunit alpha 3 2 4
MIRT682181 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682238 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682384 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682444 MTX3 metaxin 3 2 2
MIRT682604 CPA4 carboxypeptidase A4 2 2
MIRT682640 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT689327 FPR1 formyl peptide receptor 1 2 2
MIRT689730 ATXN2 ataxin 2 2 2
MIRT691036 ZNF799 zinc finger protein 799 2 2
MIRT691935 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT694884 ZNF417 zinc finger protein 417 2 2
MIRT695255 ZNF443 zinc finger protein 443 2 2
MIRT695413 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT700589 PRSS22 protease, serine 22 2 2
MIRT701428 NHLRC2 NHL repeat containing 2 2 2
MIRT702484 KIAA1328 KIAA1328 2 2
MIRT702715 IPO9 importin 9 2 2
MIRT704028 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 2
MIRT704418 CTPS1 CTP synthase 1 2 2
MIRT705750 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT712373 NAP1L1 nucleosome assembly protein 1 like 1 2 2
MIRT713520 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT731263 FASLG Fas ligand 3 1
MIRT732697 Ccr7 chemokine (C-C motif) receptor 7 2 0
MIRT732700 Snhg12 small nucleolar RNA host gene 12 2 0
MIRT734626 SYT7 synaptotagmin 7 1 0
MIRT755829 UBQLN4 ubiquilin 4 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
let-7e Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
let-7e Hydroxamic acid HDACi LAQ824 NULL NULL Microarray breast cancer cell line SKBr3 16452179 2006 down-regulated
let-7e Doxorubicin approved 31703 Microarray ovarian cancer 19237188 2009 up-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 up-regulated
let-7e Etoposide approved 36462 Microarray Normal human fibroblasts (AG01522) 19633716 2009 up-regulated
let-7e Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
let-7e 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
let-7e Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
let-7e Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse liver 19270793 2009 down-regulated
let-7e 17beta-estradiol (E2) approved 5757 Microarray rat breast 17700064 2007 down-regulated
let-7e Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 down-regulated
let-7e Ginsenoside Rh2 NULL 119307 Microarray NSCLC cell line A549 23152132 2013 down-regulated
let-7e 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) NULL 16078949 Microarray hepatocytes 23107762 2013 up-regulated
let-7e Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Doxorubicin 31703 NSC123127 approved resistant High Ovarian Cancer cell line (OV19, TOV21G, TOV112D, FUOV1, C13, OV2008, A2780CP, A2780S, IGROV1, T8, OVCAR5, IMCC3, A2008, OVCAR3, SKOV3, IOSER)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Verapamil 2520 NSC272366 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant High Colon Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer tissue and cell line (A2780)
hsa-let-7e Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-let-7e Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H1155, H358, H1993)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC7901)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive High Lung Adenocarcinoma cell line (A549)
hsa-let-7e Imatinib 5291 NSC743414 approved resistant High Gastrointestinal Stromal Tumor tissue
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Esophageal Adenocarcinoma cell line (OE19)
hsa-let-7e Doxorubicin 31703 NSC123127 approved sensitive Low Breast Cancer tissue and cell line (MCF-7)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (A2780)
hsa-let-7e Plx-4720 24180719 NSC757438 resistant High Thyroid Cancer cell line (8505c, BCPAP)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive High Colorectal Cancer cell line (DLD-1)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive Low Ovarian Cancer cell line (A2780, HO8910, ES2, CAOV3, SKOV3)
hsa-let-7e Fluorouracil 3385 NSC19893 approved sensitive Low Colorectal Cancer cell line (HCT-8)
hsa-let-7e Daunorubicin 30323 NSC82151 approved resistant High Acute Promyelocytic Leukemia cell line (HL60)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7C)
hsa-let-7e Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Non-Small Cell Lung Cancer cell line (PC-9)
hsa-let-7e Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375)
hsa-let-7e Gefitinib 123631 NSC715055 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Regorafenib 11167602 NSC763932 approved sensitive Low Colorectal Cancer cell line (HCT-116)
hsa-let-7e Ribavirin+Pegylated IFNa-2b resistant tissue (chronic hepatitis C)
hsa-let-7e Exemestane 60198 NSC713563 approved sensitive cell line (MCF-7)
hsa-let-7e 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-let-7e Ethanol+Tamoxifen resistant cell line (LY2)
hsa-let-7e Methotrexate 126941 NSC740 approved resistant cell line (HT29)
hsa-let-7e Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-let-7e Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-let-7e Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-let-7e Gemcitabine 60750 NSC613327 approved resistant cell line (HuH28)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (KYSE)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (OE19)
hsa-let-7e Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-let-7e Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)
hsa-let-7e Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-let-7e-5p Alvocidib 5287969 NSC649890 resistant
hsa-let-7e-5p Ethyl, methoxy, prodigisine 135829283 NSC742418 resistant
hsa-let-7e-5p Platinum 23939 resistant Low Ovarian Cancer tissue
hsa-let-7e-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-let-7e-5p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-let-7e-5p Platinum 23939 resistant High High-Grade Serous Ovarian Cancer tissue
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-let-7e-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-let-7e-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-let-7e-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-let-7e-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-let-7e-5p Sunitinib 5329102 NSC750690 approved sensitive tissue (clear cell renal cell carcinoma)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-let-7e-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-let-7e-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-let-7e-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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