miRTarBase - #MIRT482966


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pre-miRNA Information
pre-miRNA hsa-mir-6737   
Genomic Coordinates chr1: 153962351 - 153962420
Description Homo sapiens miR-6737 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6737-5p
Sequence 6| UUGGGGUGGUCGGCCCUGGAG |26
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs766338599 4 dbSNP
rs765728788 7 dbSNP
rs757341439 9 dbSNP
rs539511149 11 dbSNP
rs764259486 12 dbSNP
rs988937601 21 dbSNP
Putative Targets

Gene Information
Gene Symbol CSTF2   
Synonyms CstF-64
Description cleavage stimulation factor subunit 2
Transcript NM_001325   
Expression
Putative miRNA Targets on CSTF2
3'UTR of CSTF2
(miRNA target sites are highlighted)		 
>CSTF2|NM_001325|3'UTR
   1 TAGGTTTTCAAAAATACCTGGCAAGAAATCTGGAAATTCTATAATTTTGTTGAAATATTGAAAAAAGATGACCTGCATCC
  81 TAACCCTTGAATGACTCAAATCAGTGCCAGGTGGAGGACTCCCATCACCTTCTCTCAGAACAAAATCACTTCATTTTATT
 161 GTCTTAGTTTGTATATTTTCTGTGACTTGAAATAAACTTTGAACACAATTTTAGTACACTGCAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaGGUCCCG-GCUGGUGGGGUu 5'
            :|||  |   |:|||::|| 
Target 5' tcTCAGAACAAAATCACTTCAt 3'
 133 - 154 115.00 -11.30
2 
miRNA  3' gagguccCGGCUG---GUGGGGUu 5'
                 | :|||   ||:||:| 
Target 5' gaaaaaaGATGACCTGCATCCTAa 3'
 60 - 83 114.00 -11.90
3 
miRNA  3' gaggUCC--CGGCUGGUGGGGuu 5'
              |||   || |:||||::  
Target 5' gtggAGGACTCCCATCACCTTct 3'
 111 - 133 103.00 -12.10
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs369509310 12 dbSNP
rs1467080043 14 dbSNP
rs759544335 14 dbSNP
rs765184423 16 dbSNP
rs1453722104 32 dbSNP
rs775371026 34 dbSNP
rs1195559336 42 dbSNP
rs768698797 46 dbSNP
rs1205089754 52 dbSNP
rs776755593 80 dbSNP
rs1000459783 89 dbSNP
rs1249913076 89 dbSNP
rs1001323715 98 dbSNP
rs1018011425 99 dbSNP
rs1254621016 111 dbSNP
rs1234065869 134 dbSNP
rs1339204170 138 dbSNP
rs1205959815 153 dbSNP
rs899595610 156 dbSNP
rs1482691132 159 dbSNP
rs1333412579 161 dbSNP
rs761917441 164 dbSNP
rs13340756 165 dbSNP
rs1398269432 176 dbSNP
rs1310814785 183 dbSNP
rs773358306 191 dbSNP
rs1052450359 211 dbSNP
rs140575080 230 dbSNP
rs1468544604 248 dbSNP
rs1363288635 268 dbSNP
rs1423055189 269 dbSNP
rs1218445141 275 dbSNP
rs375237575 282 dbSNP
rs188516894 289 dbSNP
rs1172555092 294 dbSNP
rs1373866483 303 dbSNP
rs751909555 320 dbSNP
rs1254391226 329 dbSNP
rs1465730631 339 dbSNP
rs1486182248 343 dbSNP
rs542524482 344 dbSNP
rs1282920028 348 dbSNP
rs1227524824 349 dbSNP
rs1278442460 358 dbSNP
rs1025259422 361 dbSNP
rs1377028474 371 dbSNP
rs1337141769 397 dbSNP
rs1291007987 408 dbSNP
rs1413791982 417 dbSNP
rs1375772241 425 dbSNP
rs969610486 428 dbSNP
rs1398875880 431 dbSNP
rs954924412 456 dbSNP
rs181059913 457 dbSNP
rs1015169719 467 dbSNP
rs767981484 475 dbSNP
rs1415806108 484 dbSNP
rs1215829821 490 dbSNP
rs1475667295 491 dbSNP
rs1260038595 498 dbSNP
rs963560699 513 dbSNP
rs144795909 514 dbSNP
rs528098972 530 dbSNP
rs780432044 533 dbSNP
rs1311317065 537 dbSNP
rs1352165703 548 dbSNP
rs937424730 549 dbSNP
rs2213514 558 dbSNP
rs374951167 559 dbSNP
rs755141815 564 dbSNP
rs1041636990 566 dbSNP
rs1294863630 580 dbSNP
rs951836554 581 dbSNP
rs1325660538 589 dbSNP
rs984907496 596 dbSNP
rs904467670 624 dbSNP
rs781422730 625 dbSNP
rs1402383141 636 dbSNP
rs1211990211 688 dbSNP
rs1392308920 697 dbSNP
rs1164380016 700 dbSNP
rs1462161743 705 dbSNP
rs1263124848 727 dbSNP
rs1420347505 729 dbSNP
rs778227916 733 dbSNP
rs935822206 734 dbSNP
rs1039963204 737 dbSNP
rs1487558690 750 dbSNP
rs1243087214 756 dbSNP
rs899544018 757 dbSNP
rs923232865 761 dbSNP
rs1250591995 765 dbSNP
rs1262503691 766 dbSNP
rs1335046698 779 dbSNP
rs1274604996 789 dbSNP
rs186557162 790 dbSNP
rs998353935 797 dbSNP
rs868786555 814 dbSNP
rs1397077856 819 dbSNP
rs1368785971 835 dbSNP
rs1325270419 844 dbSNP
rs1441799653 849 dbSNP
rs1396812748 850 dbSNP
rs1168553444 855 dbSNP
rs886772771 857 dbSNP
rs913364117 861 dbSNP
rs1420652005 864 dbSNP
rs1435128445 880 dbSNP
rs1453083760 887 dbSNP
rs1194822421 888 dbSNP
rs757979836 888 dbSNP
rs866110170 888 dbSNP
rs1201938831 889 dbSNP
rs1157767173 907 dbSNP
rs1358553616 908 dbSNP
rs1273445406 950 dbSNP
rs1003858718 952 dbSNP
rs779908637 954 dbSNP
rs1345614445 957 dbSNP
rs368820361 962 dbSNP
rs1302527425 965 dbSNP
rs1234971134 966 dbSNP
rs1015100631 978 dbSNP
rs963984278 982 dbSNP
rs925069947 990 dbSNP
rs936788341 995 dbSNP
rs7879097 999 dbSNP
rs1384755234 1000 dbSNP
rs1394884614 1001 dbSNP
rs768608836 1002 dbSNP
rs1455975796 1022 dbSNP
rs1034938596 1035 dbSNP
rs75981565 1051 dbSNP
rs776594946 1058 dbSNP
rs1426650770 1059 dbSNP
rs1175045267 1068 dbSNP
rs958934312 1068 dbSNP
rs1469283680 1071 dbSNP
rs1233153450 1085 dbSNP
rs946197492 1122 dbSNP
rs1305216526 1130 dbSNP
rs190662039 1133 dbSNP
rs769778353 1142 dbSNP
rs917360789 1146 dbSNP
rs949388752 1169 dbSNP
rs1046428217 1171 dbSNP
rs905476867 1183 dbSNP
rs967356813 1202 dbSNP
rs977434012 1218 dbSNP
rs769931167 1230 dbSNP
rs935921208 1244 dbSNP
rs1039507885 1247 dbSNP
rs1313934535 1257 dbSNP
rs1437123228 1264 dbSNP
rs888587763 1319 dbSNP
rs1005980950 1320 dbSNP
rs1408119245 1346 dbSNP
rs1417952851 1346 dbSNP
rs1183814286 1355 dbSNP
rs1015113092 1358 dbSNP
rs921089282 1358 dbSNP
rs1188438714 1365 dbSNP
rs961769113 1376 dbSNP
rs1258841100 1378 dbSNP
rs933879802 1385 dbSNP
rs182900448 1394 dbSNP
rs1242820823 1399 dbSNP
rs1270102302 1408 dbSNP
rs1488216478 1414 dbSNP
rs1029921437 1416 dbSNP
rs953300344 1429 dbSNP
rs749315156 1430 dbSNP
rs1003809651 1437 dbSNP
rs1288757616 1445 dbSNP
rs1177848381 1448 dbSNP
rs1454767273 1450 dbSNP
rs1191064445 1463 dbSNP
rs925154773 1469 dbSNP
rs1160821626 1474 dbSNP
rs763153530 1494 dbSNP
rs1416778957 1495 dbSNP
rs936531148 1497 dbSNP
rs1425292245 1518 dbSNP
rs1259399511 1531 dbSNP
rs1185796595 1532 dbSNP
rs1402423744 1537 dbSNP
rs1249980188 1551 dbSNP
rs1159701540 1575 dbSNP
rs1349186486 1577 dbSNP
rs1455951538 1581 dbSNP
rs899380731 1583 dbSNP
rs73250631 1585 dbSNP
rs766568384 1585 dbSNP
rs914012255 1585 dbSNP
rs760881879 1600 dbSNP
rs1295327728 1618 dbSNP
rs1371370159 1624 dbSNP
rs1034644829 1626 dbSNP
rs1321943006 1631 dbSNP
rs1438017930 1637 dbSNP
rs1309055773 1651 dbSNP
rs143596333 1652 dbSNP
rs1459130207 1652 dbSNP
rs1225792261 1658 dbSNP
rs1014458597 1671 dbSNP
rs1169560802 1679 dbSNP
rs761231066 1679 dbSNP
rs1429020214 1701 dbSNP
rs1046440782 1702 dbSNP
rs1468061929 1729 dbSNP
rs1253709580 1732 dbSNP
rs770818986 1738 dbSNP
rs767821484 1740 dbSNP
rs977381758 1744 dbSNP
rs1469119196 1745 dbSNP
rs5967201 1745 dbSNP
rs1198223764 1746 dbSNP
rs925956833 1753 dbSNP
rs1301827738 1757 dbSNP
rs1471055706 1759 dbSNP
rs938261009 1761 dbSNP
rs1049091896 1767 dbSNP
rs1412991319 1781 dbSNP
rs1421910799 1782 dbSNP
rs957429881 1787 dbSNP
rs1323708580 1788 dbSNP
rs1388144340 1803 dbSNP
rs1166549161 1814 dbSNP
rs888689816 1818 dbSNP
rs1004828870 1820 dbSNP
rs975734034 1824 dbSNP
rs1464817863 1843 dbSNP
rs1171613717 1859 dbSNP
rs1453742775 1862 dbSNP
rs921215643 1869 dbSNP
rs933813822 1870 dbSNP
rs1417529642 1871 dbSNP
rs113280965 1874 dbSNP
rs753119361 1885 dbSNP
rs1484200926 1894 dbSNP
rs1248991749 1910 dbSNP
rs908260135 1915 dbSNP
rs939781236 1924 dbSNP
rs985802757 1935 dbSNP
rs1444834441 1952 dbSNP
rs187121793 1956 dbSNP
rs1038156296 1957 dbSNP
rs1280436205 1967 dbSNP
rs898150114 1978 dbSNP
rs1333502874 1983 dbSNP
rs1305802576 1985 dbSNP
rs1410060439 1994 dbSNP
rs1231985409 2004 dbSNP
rs1352042329 2028 dbSNP
rs1032695800 2034 dbSNP
rs1295253529 2045 dbSNP
rs1434025475 2045 dbSNP
rs1001898965 2075 dbSNP
rs764727889 2078 dbSNP
rs894739409 2080 dbSNP
rs1014409518 2082 dbSNP
rs759428020 2090 dbSNP
rs1183089933 2099 dbSNP
rs967421758 2110 dbSNP
rs998932668 2114 dbSNP
rs1187725377 2117 dbSNP
rs1204956940 2126 dbSNP
rs1486271261 2145 dbSNP
rs1033140061 2149 dbSNP
rs1203929270 2171 dbSNP
rs1236670379 2174 dbSNP
rs868636668 2176 dbSNP
rs957584838 2185 dbSNP
rs1228612410 2195 dbSNP
rs975470283 2196 dbSNP
rs1028631682 2198 dbSNP
rs1413885257 2199 dbSNP
rs955292769 2202 dbSNP
rs1418439358 2211 dbSNP
rs986560873 2216 dbSNP
rs1336015190 2217 dbSNP
rs908373509 2221 dbSNP
rs1384330225 2225 dbSNP
rs749885951 2227 dbSNP
rs1160083383 2232 dbSNP
rs1458988200 2241 dbSNP
rs112627370 2246 dbSNP
rs1164511995 2256 dbSNP
rs1473308177 2259 dbSNP
rs775289253 2268 dbSNP
rs1191593786 2273 dbSNP
rs1446995724 2276 dbSNP
rs1410178898 2277 dbSNP
rs1246882733 2284 dbSNP
rs1208857158 2289 dbSNP
rs1330750047 2292 dbSNP
rs919716104 2299 dbSNP
rs1232303655 2300 dbSNP
rs1356710825 2309 dbSNP
rs937644055 2311 dbSNP
rs765401301 2328 dbSNP
rs1054816583 2329 dbSNP
rs1413512997 2336 dbSNP
rs1321273836 2340 dbSNP
rs1325825273 2340 dbSNP
rs1437303374 2347 dbSNP
rs1315394440 2351 dbSNP
rs1392416247 2367 dbSNP
rs1325395328 2369 dbSNP
rs779818627 2380 dbSNP
rs894692680 2386 dbSNP
rs751211682 2389 dbSNP
rs141629759 2408 dbSNP
rs903348693 2412 dbSNP
rs1268418759 2422 dbSNP
rs1341810480 2425 dbSNP
rs999059643 2432 dbSNP
rs1166589795 2436 dbSNP
rs1475357729 2437 dbSNP
rs1033500778 2445 dbSNP
rs1391381805 2452 dbSNP
rs1191086022 2453 dbSNP
rs1465804580 2461 dbSNP
rs1250609242 2473 dbSNP
rs1220353498 2497 dbSNP
rs893235891 2523 dbSNP
rs997210017 2527 dbSNP
rs1212637069 2531 dbSNP
rs7062004 2547 dbSNP
rs901326554 2561 dbSNP
rs111821384 2587 dbSNP
rs955406730 2596 dbSNP
rs748045325 2607 dbSNP
rs1437456866 2614 dbSNP
rs1051489957 2630 dbSNP
rs1487884672 2635 dbSNP
rs763721458 2651 dbSNP
rs961182623 2653 dbSNP
rs973945663 2663 dbSNP
rs1392714432 2670 dbSNP
rs1475565243 2673 dbSNP
rs1190168600 2674 dbSNP
rs1478138563 2687 dbSNP
rs1007676543 2694 dbSNP
rs111425079 2703 dbSNP
rs1392833602 2706 dbSNP
rs1275108245 2712 dbSNP
rs1433270655 2722 dbSNP
rs1175853534 2727 dbSNP
rs1345728219 2740 dbSNP
rs777816815 2743 dbSNP
rs1219941738 2756 dbSNP
rs1376595333 2761 dbSNP
rs1369852316 2778 dbSNP
rs1277930679 2781 dbSNP
rs1441764910 2787 dbSNP
rs990858933 2794 dbSNP
rs1351468876 2824 dbSNP
rs373189427 2829 dbSNP
rs1433366289 2830 dbSNP
rs949072538 2835 dbSNP
rs758988598 2840 dbSNP
rs1375425078 2856 dbSNP
rs903467716 2858 dbSNP
rs1316383241 2874 dbSNP
rs1414502703 2883 dbSNP
rs183028366 2903 dbSNP
rs1431524514 2906 dbSNP
rs1472093765 2910 dbSNP
rs1252271055 2936 dbSNP
rs1184132489 2943 dbSNP
rs1484639727 2947 dbSNP
rs958203077 2948 dbSNP
rs1009446742 2949 dbSNP
rs1313962070 2951 dbSNP
rs1054650278 2974 dbSNP
rs1228007685 2975 dbSNP
rs138737369 2976 dbSNP
rs187652717 2978 dbSNP
rs1413269283 2984 dbSNP
rs996931259 2986 dbSNP
rs1378938188 2992 dbSNP
rs1236229045 2995 dbSNP
rs1303869028 3020 dbSNP
rs755338291 3024 dbSNP
rs1360378295 3043 dbSNP
rs1156399166 3061 dbSNP
rs781332722 3068 dbSNP
rs1352973382 3073 dbSNP
rs1203288946 3075 dbSNP
rs926716334 3085 dbSNP
rs1285792769 3086 dbSNP
rs1182359611 3100 dbSNP
rs891105243 3110 dbSNP
rs1008211588 3113 dbSNP
rs1484230951 3115 dbSNP
rs1447108606 3126 dbSNP
rs1208240424 3130 dbSNP
rs959478255 3132 dbSNP
rs1270202623 3153 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaggucccGGCUGGUGGGGUu 5'
                  ||  :| ||||| 
Target 5' ----uccuCCUCUCCCCCCAc 3'
 		1 - 17
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000415585.2 | 3UTR | UCCUCCUCUCCCCCCACCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
67 hsa-miR-6737-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066215 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT074413 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT125300 MID1IP1 MID1 interacting protein 1 2 2
MIRT153951 NCOA3 nuclear receptor coactivator 3 2 2
MIRT452776 FAM136A family with sequence similarity 136 member A 2 2
MIRT452977 CABP4 calcium binding protein 4 2 2
MIRT454128 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT455242 DDX39B DExD-box helicase 39B 2 10
MIRT459007 UQCRH ubiquinol-cytochrome c reductase hinge protein 2 2
MIRT459463 MUC17 mucin 17, cell surface associated 2 4
MIRT460871 UBE2S ubiquitin conjugating enzyme E2 S 2 2
MIRT461264 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 2
MIRT464540 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT465268 TRIM28 tripartite motif containing 28 2 2
MIRT465871 TMEM43 transmembrane protein 43 2 4
MIRT466228 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT468417 SETD1B SET domain containing 1B 2 2
MIRT468684 SEC22C SEC22 homolog C, vesicle trafficking protein 2 4
MIRT473399 MDM4 MDM4, p53 regulator 2 2
MIRT473517 MAX MYC associated factor X 2 2
MIRT474511 KLHDC8A kelch domain containing 8A 2 2
MIRT475801 HDGF heparin binding growth factor 2 2
MIRT479493 CDH6 cadherin 6 2 2
MIRT480770 BMP2 bone morphogenetic protein 2 2 2
MIRT481418 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT482966 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT483380 SPATA6 spermatogenesis associated 6 2 4
MIRT483677 CYP11A1 cytochrome P450 family 11 subfamily A member 1 2 2
MIRT484328 EPN1 epsin 1 2 4
MIRT484963 UCK1 uridine-cytidine kinase 1 2 2
MIRT485908 PGPEP1 pyroglutamyl-peptidase I 2 4
MIRT488149 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488943 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 6
MIRT491835 ZBTB7A zinc finger and BTB domain containing 7A 2 4
MIRT493026 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT499374 PLCG2 phospholipase C gamma 2 2 11
MIRT499723 USH1G USH1 protein network component sans 2 4
MIRT500349 ZNF385A zinc finger protein 385A 2 2
MIRT509574 HIST2H2AB histone cluster 2 H2A family member b 2 4
MIRT512794 GLRX glutaredoxin 2 2
MIRT513291 SETBP1 SET binding protein 1 2 2
MIRT515697 ZNF321P zinc finger protein 321, pseudogene 2 2
MIRT518255 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT522026 PAQR3 progestin and adipoQ receptor family member 3 2 4
MIRT523169 HIST3H3 histone cluster 3 H3 2 2
MIRT524036 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT533476 TRIM71 tripartite motif containing 71 2 2
MIRT541488 ADM adrenomedullin 2 2
MIRT553987 SRPR SRP receptor alpha subunit 2 2
MIRT571445 YKT6 YKT6 v-SNARE homolog 2 2
MIRT574889 Plcg2 phospholipase C, gamma 2 2 7
MIRT607544 GLI2 GLI family zinc finger 2 2 2
MIRT607688 MAPK10 mitogen-activated protein kinase 10 2 2
MIRT610072 CRLF1 cytokine receptor like factor 1 2 2
MIRT610573 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT614041 THBS2 thrombospondin 2 2 2
MIRT626318 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT634005 RIF1 replication timing regulatory factor 1 2 2
MIRT639619 FGF19 fibroblast growth factor 19 2 2
MIRT647343 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT689704 ATXN2 ataxin 2 2 2
MIRT691170 APOL6 apolipoprotein L6 2 2
MIRT693165 NPR1 natriuretic peptide receptor 1 2 2
MIRT711727 NUPL2 nucleoporin like 2 2 2
MIRT711806 ELN elastin 2 2
MIRT721546 FXN frataxin 2 2
MIRT722979 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6737 Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-6737 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-6737-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-6737-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-6737-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-6737-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-6737-5p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-6737-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-6737-5p Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)

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