pre-miRNA Information
pre-miRNA hsa-mir-3179-1   
Genomic Coordinates chr16: 14901508 - 14901591
Description Homo sapiens miR-3179-1 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-2   
Genomic Coordinates chr16: 16300159 - 16300242
Description Homo sapiens miR-3179-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-3   
Genomic Coordinates chr16: 18411894 - 18411977
Description Homo sapiens miR-3179-3 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-4   
Genomic Coordinates chr16: 18494493 - 18494576
Description Homo sapiens miR-3179-4 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-3179
Sequence 52| AGAAGGGGUGAAAUUUAAACGU |73
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1351100204 1 dbSNP
rs1398613616 4 dbSNP
rs1340262765 20 dbSNP
rs1229893475 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SUMO1   
Synonyms DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1
Description small ubiquitin-like modifier 1
Transcript NM_001005782   
Other Transcripts NM_001005781 , NM_003352   
Expression
Putative miRNA Targets on SUMO1
3'UTR of SUMO1
(miRNA target sites are highlighted)
>SUMO1|NM_001005782|3'UTR
   1 ATATTCTTTTTATTTTTTTTCTTTTCCCTCAATCCTTTTTTATTTTTAAAAATAGTTCTTTTGTAATGTGGTGTTCAAAA
  81 CGGAATTGAAAACTGGCACCCCATCTCTTTGAAACATCTGGTAATTTGAATTCTAGTGCTCATTATTCATTATTGTTTGT
 161 TTTCATTGTGCTGATTTTTGGTGATCAAGCCTCAGTCCCCTTCATATTACCCTCTCCTTTTTAAAAATTACGTGTGCACA
 241 GAGAGGTCACCTTTTTCAGGACATTGCATTTTCAGGCTTGTGGTGATAAATAAGATCGACCAATGCAAGTGTTCATAATG
 321 ACTTTCCAATTGGCCCTGATGTTCTAGCATGTGATTACTTCACTCCTGGACTGTGACTTTCAGTGGGAGATGGAAGTTTT
 401 TCAGAGAACTGAACTGTGGAAAAATGACCTTTCCTTAACTTGAAGCTACTTTTAAAATTTGAGGGTCTGGACCAAAAGAA
 481 GAGGAATATCAGGTTGAAGTCAAGATGACAGATAAGGTGAGAGTAATGACTAACTCCAAAGATGGCTTCACTGAAGAAAA
 561 GGCATTTTAAGATTTTTTAAAAATCTTGTCAGAAGATCCCAGAAAAGTTCTAATTTTCATTAGCAATTAATAAAGCTATA
 641 CATGCAGAAATGAATACAACAGAACACTGCTCTTTTTGATTTTATTTGTACTTTTTGGCCTGGGATATGGGTTTTAAATG
 721 GACATTGTCTGTACCAGCTTCATTAAAATAAACAATATTTGTAAAAATCATACTAATGCTTATTTTATTTTAATTGTATA
 801 GAAAGAAAAAAATGCCTAAAATAAGGTTTTCTTGCATAAATACTGGAAATTGCACATGGTACAAATTTTTTCTTCATTAC
 881 TGTACAGTGATGATGTTAATGACTTTGAAGCACTGAAAGTTACTGAAGTGCCTTCTGAATCAAGGATTTAATTAAGGCCA
 961 CAATACCTTTTTAATACTCAGTGTTCTGTTTTTTTAAAAACTTGATATTCCTGTATGGTGCATATATGATACAGTTACCT
1041 AATCATGTTGAATAAATGGGCATGCCAAAAATT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ugCAAAUUUAAAGU--GGGGAAGa 5'
            | | ||:  |||  ||||||| 
Target 5' gtGATCAAGCCTCAGTCCCCTTCa 3'
181 - 204 154.00 -11.20
2
miRNA  3' ugcAAAUUU--AAAGUGGGGAAGa 5'
             || |||  |  |||||| || 
Target 5' gaaTTGAAAACTGGCACCCCATCt 3'
83 - 106 129.00 -13.80
3
miRNA  3' ugcAAAUUUAAAGUGGGGAAGa 5'
             ||||  |||: :|::||| 
Target 5' cttTTTATTTTTTTTCTTTTCc 3'
6 - 27 119.00 -6.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
333613 475 ClinVar
333612 545 ClinVar
333611 724 ClinVar
895353 753 ClinVar
895352 776 ClinVar
895351 814 ClinVar
333610 884 ClinVar
333609 944 ClinVar
898330 1038 ClinVar
COSN31492697 19 COSMIC
COSN13963965 21 COSMIC
COSN30157018 21 COSMIC
COSN31586812 32 COSMIC
COSN30156998 34 COSMIC
COSN31496610 46 COSMIC
COSN30492430 47 COSMIC
COSN24299284 57 COSMIC
COSN26997461 58 COSMIC
COSN30184979 68 COSMIC
COSN30148999 76 COSMIC
COSN26997457 82 COSMIC
COSN30474899 100 COSMIC
COSN31610298 291 COSMIC
COSN31529156 406 COSMIC
COSN30040479 427 COSMIC
COSN18793733 588 COSMIC
COSN17131955 631 COSMIC
COSN15660412 721 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs775681074 3 dbSNP
rs1163997856 4 dbSNP
rs770432722 6 dbSNP
rs752984189 8 dbSNP
rs1270845780 13 dbSNP
rs1366583892 16 dbSNP
rs760066247 19 dbSNP
rs777261065 20 dbSNP
rs915971988 21 dbSNP
rs1388244381 22 dbSNP
rs771198991 27 dbSNP
rs747026305 28 dbSNP
rs1056292132 41 dbSNP
rs1322724073 43 dbSNP
rs1297261106 47 dbSNP
rs778103751 48 dbSNP
rs1211520779 49 dbSNP
rs1451937257 55 dbSNP
rs1311238836 63 dbSNP
rs941526430 74 dbSNP
rs1246042320 76 dbSNP
rs1192097228 79 dbSNP
rs910094705 82 dbSNP
rs572535139 84 dbSNP
rs1273703658 85 dbSNP
rs964487195 91 dbSNP
rs1206431723 93 dbSNP
rs1269551812 95 dbSNP
rs1186668776 99 dbSNP
rs1180722234 103 dbSNP
rs951661514 119 dbSNP
rs534230755 121 dbSNP
rs1188069332 127 dbSNP
rs1410948115 137 dbSNP
rs1455386351 139 dbSNP
rs922857978 141 dbSNP
rs566873208 142 dbSNP
rs866479633 148 dbSNP
rs975751372 163 dbSNP
rs548561063 166 dbSNP
rs966102169 168 dbSNP
rs1348109611 171 dbSNP
rs1397105339 175 dbSNP
rs958418130 189 dbSNP
rs1288186565 197 dbSNP
rs1017406384 205 dbSNP
rs1000622330 210 dbSNP
rs1230557002 215 dbSNP
rs1289855941 217 dbSNP
rs1282232508 223 dbSNP
rs1329372958 224 dbSNP
rs529216647 231 dbSNP
rs1021147493 232 dbSNP
rs1017319375 241 dbSNP
rs568234416 242 dbSNP
rs1250914207 246 dbSNP
rs1471502347 257 dbSNP
rs1009797907 272 dbSNP
rs1007350221 273 dbSNP
rs957188959 277 dbSNP
rs145284427 282 dbSNP
rs998757452 285 dbSNP
rs1359971318 286 dbSNP
rs1288293017 294 dbSNP
rs1369193295 297 dbSNP
rs903070328 298 dbSNP
rs1308984081 306 dbSNP
rs1373668386 310 dbSNP
rs1218275345 317 dbSNP
rs1046077492 319 dbSNP
rs11545248 326 dbSNP
rs183187867 329 dbSNP
rs11545249 335 dbSNP
rs905204482 336 dbSNP
rs941474399 337 dbSNP
rs1804594 348 dbSNP
rs1252263609 363 dbSNP
rs1488314827 370 dbSNP
rs910040720 371 dbSNP
rs1038383862 387 dbSNP
rs564254971 394 dbSNP
rs941461237 397 dbSNP
rs1433862720 404 dbSNP
rs1167993806 420 dbSNP
rs149269552 424 dbSNP
rs1047576045 426 dbSNP
rs780743647 427 dbSNP
rs1349670078 437 dbSNP
rs1050860 454 dbSNP
rs1434695684 454 dbSNP
rs929225046 464 dbSNP
rs1369238761 468 dbSNP
rs754482827 475 dbSNP
rs1296204114 484 dbSNP
rs922840948 489 dbSNP
rs977416624 490 dbSNP
rs975772658 494 dbSNP
rs964693321 497 dbSNP
rs944378706 499 dbSNP
rs1259098073 501 dbSNP
rs1185384098 531 dbSNP
rs1485821347 532 dbSNP
rs1259137847 539 dbSNP
rs1488911295 540 dbSNP
rs747664973 545 dbSNP
rs979148070 551 dbSNP
rs1485212363 553 dbSNP
rs1251616179 557 dbSNP
rs1229523934 562 dbSNP
rs985859634 573 dbSNP
rs1169799410 574 dbSNP
rs1032773196 578 dbSNP
rs1167311993 579 dbSNP
rs1351311401 579 dbSNP
rs967808992 579 dbSNP
rs527345489 583 dbSNP
rs1436569375 587 dbSNP
rs1270716925 607 dbSNP
rs1378295047 610 dbSNP
rs1226436111 614 dbSNP
rs977227739 630 dbSNP
rs1335800780 633 dbSNP
rs1021116549 641 dbSNP
rs967617204 657 dbSNP
rs1466327765 659 dbSNP
rs1193944541 665 dbSNP
rs1237455346 676 dbSNP
rs1433733355 678 dbSNP
rs1311277906 680 dbSNP
rs1472085151 682 dbSNP
rs1184024868 687 dbSNP
rs1414977423 697 dbSNP
rs1472428302 712 dbSNP
rs1157974721 718 dbSNP
rs867404338 720 dbSNP
rs886055457 724 dbSNP
rs1458384956 726 dbSNP
rs1414336228 733 dbSNP
rs1358554118 737 dbSNP
rs1035640561 753 dbSNP
rs559734031 757 dbSNP
rs1300225740 767 dbSNP
rs1002466992 770 dbSNP
rs72923015 776 dbSNP
rs1372988721 786 dbSNP
rs1038351086 787 dbSNP
rs1169384975 793 dbSNP
rs1227504826 794 dbSNP
rs1475245127 807 dbSNP
rs377075241 808 dbSNP
rs1419644685 809 dbSNP
rs1185358137 813 dbSNP
rs1370102740 813 dbSNP
rs894459902 813 dbSNP
rs753364030 814 dbSNP
rs1005572567 815 dbSNP
rs887219619 827 dbSNP
rs1251010928 837 dbSNP
rs1258754826 843 dbSNP
rs1472479659 850 dbSNP
rs766211759 856 dbSNP
rs1479641364 863 dbSNP
rs1250689945 864 dbSNP
rs1158701434 865 dbSNP
rs1423850188 866 dbSNP
rs929171995 875 dbSNP
rs1336117266 876 dbSNP
rs1375949772 879 dbSNP
rs555380378 884 dbSNP
rs1305932711 886 dbSNP
rs1040663268 887 dbSNP
rs1352625966 890 dbSNP
rs1240027146 895 dbSNP
rs888507325 896 dbSNP
rs373040487 906 dbSNP
rs943315607 916 dbSNP
rs1047139249 938 dbSNP
rs537401465 944 dbSNP
rs979116877 956 dbSNP
rs12991014 960 dbSNP
rs967778084 963 dbSNP
rs913688448 972 dbSNP
rs1336531532 973 dbSNP
rs760340269 977 dbSNP
rs1203510159 979 dbSNP
rs901370347 986 dbSNP
rs561161012 995 dbSNP
rs1439262150 996 dbSNP
rs1182086716 1013 dbSNP
rs1041296887 1016 dbSNP
rs1476774106 1020 dbSNP
rs987910782 1022 dbSNP
rs1395670886 1027 dbSNP
rs1429014543 1034 dbSNP
rs1166559333 1037 dbSNP
rs754651477 1038 dbSNP
rs753262687 1044 dbSNP
rs1391703944 1046 dbSNP
rs961124453 1048 dbSNP
rs1323161140 1064 dbSNP
rs199601666 1066 dbSNP
rs1035207757 1068 dbSNP
rs773233092 1078 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ugcaaauuuaaAGUGGGGAAGa 5'
                     || ||||||| 
Target 5' ------cacccUCCCCCCUUCu 3'
1 - 16
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000296257.5 | 3UTR | CACCCUCCCCCCUUCUCCCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
Click to see details
133 hsa-miR-3179 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102087 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT110061 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112198 BTG2 BTG anti-proliferation factor 2 2 2
MIRT117668 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT146657 MINK1 misshapen like kinase 1 2 2
MIRT175505 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT180535 TXNIP thioredoxin interacting protein 2 2
MIRT190624 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT190650 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT366902 NONO non-POU domain containing octamer binding 2 2
MIRT443554 ZFP3 ZFP3 zinc finger protein 2 2
MIRT445953 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT446042 HMCN1 hemicentin 1 2 2
MIRT447968 MSH6 mutS homolog 6 2 2
MIRT448634 ONECUT1 one cut homeobox 1 2 2
MIRT449316 MRO maestro 2 2
MIRT451380 C19orf43 telomerase RNA component interacting RNase 2 2
MIRT451547 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451807 CDCA3 cell division cycle associated 3 2 4
MIRT451916 ILK integrin linked kinase 2 2
MIRT451938 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452189 KIAA1456 KIAA1456 2 2
MIRT452498 HMGXB3 HMG-box containing 3 2 2
MIRT452548 ZNF467 zinc finger protein 467 2 2
MIRT453844 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454515 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455363 KDM5C lysine demethylase 5C 2 2
MIRT455455 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455628 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 10
MIRT455639 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 10
MIRT455690 GLO1 glyoxalase I 2 2
MIRT456300 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT456784 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT456819 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457566 ZNF34 zinc finger protein 34 2 2
MIRT457604 IDS iduronate 2-sulfatase 2 2
MIRT458236 NXPH3 neurexophilin 3 2 2
MIRT458313 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458350 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458670 GPR35 G protein-coupled receptor 35 2 2
MIRT459675 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT461126 RAB36 RAB36, member RAS oncogene family 2 2
MIRT461918 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462301 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463520 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464378 URM1 ubiquitin related modifier 1 2 2
MIRT464614 UBE4B ubiquitination factor E4B 2 2
MIRT464711 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465520 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465974 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466058 TMEM189 transmembrane protein 189 2 2
MIRT466548 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT466647 TAGLN2 transgelin 2 2 2
MIRT467357 SP2 Sp2 transcription factor 2 2
MIRT468744 SDC2 syndecan 2 2 2
MIRT470244 PRRC2A proline rich coiled-coil 2A 2 2
MIRT471426 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT471732 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472190 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472450 NAV2 neuron navigator 2 2 6
MIRT474563 KLHDC3 kelch domain containing 3 2 2
MIRT474936 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475165 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475399 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT475426 ICK intestinal cell kinase 2 2
MIRT477090 FAM168A family with sequence similarity 168 member A 2 2
MIRT478458 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478953 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480096 CALR calreticulin 2 2
MIRT481924 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT483217 APOA1 apolipoprotein A1 2 6
MIRT483882 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483923 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483942 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484209 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484512 SYT7 synaptotagmin 7 2 2
MIRT484709 RNF11 ring finger protein 11 2 2
MIRT485356 MYO1C myosin IC 2 4
MIRT485615 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT486584 ZNF619 zinc finger protein 619 2 2
MIRT487013 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487621 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487801 GPR20 G protein-coupled receptor 20 2 4
MIRT488134 GPR107 G protein-coupled receptor 107 2 2
MIRT488773 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488854 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489783 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490102 FN3K fructosamine 3 kinase 2 2
MIRT490389 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT490434 MYL9 myosin light chain 9 2 2
MIRT490451 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490880 OSBP oxysterol binding protein 2 2
MIRT491037 ALPK3 alpha kinase 3 2 2
MIRT491250 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491748 SEMA3F semaphorin 3F 2 2
MIRT492235 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492490 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492505 RANBP10 RAN binding protein 10 2 4
MIRT492773 PDGFB platelet derived growth factor subunit B 2 2
MIRT492922 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT493459 ITFG3 family with sequence similarity 234 member A 2 2
MIRT493654 HDLBP high density lipoprotein binding protein 2 2
MIRT494011 DUSP9 dual specificity phosphatase 9 2 2
MIRT499412 PLCG2 phospholipase C gamma 2 2 4
MIRT499552 C15orf43 telomere repeat binding bouquet formation protein 2 2 2
MIRT501836 NCOA2 nuclear receptor coactivator 2 2 2
MIRT501950 MAT2A methionine adenosyltransferase 2A 2 10
MIRT504066 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT504509 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT508466 HOXB6 homeobox B6 2 4
MIRT512373 CPM carboxypeptidase M 2 2
MIRT513578 EVX1 even-skipped homeobox 1 2 2
MIRT517763 ZNF366 zinc finger protein 366 2 4
MIRT519773 ZNF354B zinc finger protein 354B 2 8
MIRT523568 GGCX gamma-glutamyl carboxylase 2 4
MIRT532802 CLDN11 claudin 11 2 2
MIRT544299 TSPYL1 TSPY like 1 2 2
MIRT544862 MYH2 myosin heavy chain 2 2 4
MIRT556731 KLHL15 kelch like family member 15 2 4
MIRT564347 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568924 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT569012 CXorf36 chromosome X open reading frame 36 2 2
MIRT569256 FAM129B family with sequence similarity 129 member B 2 2
MIRT569591 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT569779 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT570034 FAM228A family with sequence similarity 228 member A 2 2
MIRT573803 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574190 ZNF264 zinc finger protein 264 2 2
MIRT576153 Hmox1 heme oxygenase 1 2 2
MIRT611311 CA8 carbonic anhydrase 8 2 4
MIRT673429 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT674976 SH3BP2 SH3 domain binding protein 2 2 2
MIRT692712 MEAF6 MYST/Esa1 associated factor 6 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-3179 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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