miRTarBase - #MIRT485055


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pre-miRNA Information
pre-miRNA hsa-mir-3942   
Genomic Coordinates chr15: 35372256 - 35372364
Description Homo sapiens miR-3942 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3942-3p
Sequence 65| UUUCAGAUAACAGUAUUACAU |85
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 15 - 35372296 29233923 MiREDiBase
A-to-I 10 15 - 35372291 23291724, 29233923 MiREDiBase
A-to-I 18 15 - 35372283 23291724, 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN1674243 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1043666670 6 dbSNP
rs1264147291 18 dbSNP
rs1223363654 20 dbSNP
Putative Targets

Gene Information
Gene Symbol SUCO   
Synonyms C1orf9, CH1, OPT, SLP1
Description SUN domain containing ossification factor
Transcript NM_014283   
Other Transcripts NM_016227   
Expression
Putative miRNA Targets on SUCO
3'UTR of SUCO
(miRNA target sites are highlighted)		 
>SUCO|NM_014283|3'UTR
   1 AATTAATTGAACTTTTCATACAGAAGACTTTTTTGTTGTTGTTCTTTGAAGAACAGTCTGTAGTATTTGAAGGGTTTGGG
  81 GGAGGGAGAAAATATTAATGGGAAAGGCATTCAGAAATTATGGTTTCTACCTTTTTAAAAAGTAGATGGGATTGTGTCAA
 161 TCTTGGTTAATGAGCTACAGTTTTACAAAGCTGATCACTTCCTATAAGGACAATGGTAGACATTTTATAAAGATGTTTTT
 241 TCACAAGATTAATTACTGGGACAAAAGTAATTTGGAAGCCCAGTTCCTTAGGTGGGATAGGAATGAAAGCCTAAACCTCT
 321 TCCTTTAGCTTTGTTCCTATTTCTTGCACCTTCCCATATTTATGTGCCTTTTGTCTATTTATAATGCCACTGGAAGAGGA
 401 GGGATAACTTTTTCTGTTATTTGATTTCTTTTATAACTTTGTTAGGTTTTTGAAGCTGCAAACACTACAATGCTTTGAGG
 481 GGGTCTGTGCCTGAAGCTCAGGAGTGTGGATCAGACAGTCTAAAGATCCTAAAAACTTGCCAACTGGATCTTTGTTTAGC
 561 AAACTCACTGGAAATGAACACTTAATGGAATTTTTAAGTCTGTTCTGTTAGGTAGATGGTGATGCTCTTGTTATTTTCAC
 641 TTATTCAGACTGGATTACTTCTTACTTAGTTACTAACTCAATGAGGAAAAATCCCTACAGGATCTTTTTTTGCAAACAAC
 721 TGATATATGCAGACAAATTTTTGACAAATTCACCTTTTAAACACACTTAACCATTTGTGAAGGTTTTCTTTAGCTTACAT
 801 TTTAAACATACACAATAAACACTAATCCTCCAAACTTTCACTGTTTTTATTAGTATGAATATAAAATTTGAAGGTTTGGC
 881 CAATTAGTACAAGTCTCATGATATAATCACTGCCTGCATACATATGCACAGATCCAGTTAGTGAGTTTGTCAAGCTTAAT
 961 CTAATTGGTTAAGTCTAAAGAGATTATTATTCCTTGATGTTTGCTTTGTATTGGCTACAAATGTGCAGAGGTAATACATA
1041 TGTGATGTCGATGTCTCTGTCTTTTTTTTTGTCTTTAAAAAATAATTGGCAGCAACTGTATTTGAATAAAATGATTTCTT
1121 AGTATGATTGTACAGTAATGAATGAAAGTGGAACATGTTTCTTTTTGAAAGGGAGAGAATTGACCATTTATTGTTGTGAT
1201 GTTTAAGTTATAACTTATTGAGCACTTTTAGTAGTGATAACTGTTTTTAAACTTGCCTAATACCTTTCTTGGGTATTGTT
1281 TGTAATGTGACTTATTTAACGCCTTTTTTGTTTGTTTAAGTTGCTGCTTTAGGTTAACAGCGTGTTTTAGAAGATTTAAA
1361 TTTCTTTCCTGTCTGCACAATTAGCTATTCAGAGCAAGAGGGCCTGATTTTATAGAAGCCCCTTGAAAAGAGGTCCAGAT
1441 GAGAGCAGAGATACAGTGAGAAATTATGTGATCTGTGTGTTGTGGGAAGAGAATTTTCAATATGTAACTACGGAGCTGTA
1521 GTGCCATTAGAAACTGTGAATTTCCAAATAAATCTGAACACTTGTCTTTATTAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uacaUUAUGACAAUAGACUUu 5'
              ||||     ||||||| 
Target 5' tccaAATA----AATCTGAAc 3'
 1543 - 1559 143.00 -5.30
2 
miRNA  3' uacaUUAUGACA--AUAGACUUu 5'
              |:| ||||  |||:|||| 
Target 5' gaacAGT-CTGTAGTATTTGAAg 3'
 51 - 72 142.00 -9.30
3 
miRNA  3' uacauuaUGACAAUAGACUUu 5'
                 |||| |||:|||| 
Target 5' ggcagcaACTG-TATTTGAAt 3'
 1088 - 1107 141.00 -9.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31613535 8 COSMIC
COSN1092629 28 COSMIC
COSN30531335 56 COSMIC
COSN30521026 79 COSMIC
COSN31581485 105 COSMIC
COSN28233460 147 COSMIC
COSN31483367 235 COSMIC
COSN6008557 390 COSMIC
COSN31607815 432 COSMIC
COSN2473483 471 COSMIC
COSN20090404 950 COSMIC
COSN31590959 1050 COSMIC
COSN27411856 1071 COSMIC
COSN20090405 1096 COSMIC
COSN19055126 1120 COSMIC
COSN7184593 1279 COSMIC
COSN1413362 1514 COSMIC
COSN8322388 1563 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs567952871 22 dbSNP
rs948924735 23 dbSNP
rs776669473 25 dbSNP
rs746122296 28 dbSNP
rs1367422960 29 dbSNP
rs770112524 30 dbSNP
rs1314925812 32 dbSNP
rs374884613 33 dbSNP
rs762358540 33 dbSNP
rs775882516 34 dbSNP
rs373402261 36 dbSNP
rs764580214 38 dbSNP
rs774929879 40 dbSNP
rs143761287 51 dbSNP
rs765942837 52 dbSNP
rs1166213329 56 dbSNP
rs1455278399 60 dbSNP
rs1052680431 64 dbSNP
rs1377890020 78 dbSNP
rs1222393848 79 dbSNP
rs1197884949 83 dbSNP
rs879210188 89 dbSNP
rs893670457 97 dbSNP
rs1009446700 104 dbSNP
rs778939193 119 dbSNP
rs1205709982 122 dbSNP
rs1482700246 125 dbSNP
rs891469987 128 dbSNP
rs868777843 130 dbSNP
rs1293212380 137 dbSNP
rs556591835 139 dbSNP
rs1490853394 142 dbSNP
rs1021298254 143 dbSNP
rs189837722 146 dbSNP
rs545489515 147 dbSNP
rs900323742 150 dbSNP
rs553949900 151 dbSNP
rs996440045 152 dbSNP
rs572223353 155 dbSNP
rs1030237289 160 dbSNP
rs1329657164 161 dbSNP
rs1419923013 165 dbSNP
rs745979115 167 dbSNP
rs772233547 169 dbSNP
rs746400018 180 dbSNP
rs1033663160 187 dbSNP
rs961390014 189 dbSNP
rs1442623265 196 dbSNP
rs1402461988 197 dbSNP
rs1171561983 199 dbSNP
rs974137462 202 dbSNP
rs1365273915 203 dbSNP
rs920037080 205 dbSNP
rs1472211460 208 dbSNP
rs542443842 210 dbSNP
rs1249603121 214 dbSNP
rs1458968346 221 dbSNP
rs948907174 228 dbSNP
rs980718487 230 dbSNP
rs1180103848 243 dbSNP
rs928823367 244 dbSNP
rs938897874 247 dbSNP
rs984203190 253 dbSNP
rs1017098021 261 dbSNP
rs1053311431 262 dbSNP
rs560878151 269 dbSNP
rs1200041990 280 dbSNP
rs891438721 281 dbSNP
rs947075979 283 dbSNP
rs1229444368 284 dbSNP
rs961853233 285 dbSNP
rs972983034 287 dbSNP
rs531499782 292 dbSNP
rs922865876 301 dbSNP
rs1340485189 313 dbSNP
rs1295978658 320 dbSNP
rs543054624 329 dbSNP
rs564549034 330 dbSNP
rs1386734089 340 dbSNP
rs1042772200 341 dbSNP
rs531934519 348 dbSNP
rs1456572201 350 dbSNP
rs934256581 357 dbSNP
rs1395246737 362 dbSNP
rs374651402 363 dbSNP
rs181436719 386 dbSNP
rs1473099625 392 dbSNP
rs1238088562 402 dbSNP
rs746908304 405 dbSNP
rs900282545 407 dbSNP
rs1381018431 408 dbSNP
rs565603399 410 dbSNP
rs1053949038 412 dbSNP
rs1245759327 416 dbSNP
rs1209741840 419 dbSNP
rs1328832219 420 dbSNP
rs147218449 421 dbSNP
rs1362255964 433 dbSNP
rs945215603 446 dbSNP
rs1030547372 450 dbSNP
rs186025009 456 dbSNP
rs906438703 461 dbSNP
rs1005186382 462 dbSNP
rs568004098 468 dbSNP
rs1197775787 469 dbSNP
rs1014876150 471 dbSNP
rs961355833 480 dbSNP
rs1386116633 483 dbSNP
rs1327701564 488 dbSNP
rs1194400774 490 dbSNP
rs1405845117 507 dbSNP
rs1413038340 512 dbSNP
rs140548304 514 dbSNP
rs1471892044 520 dbSNP
rs1027069887 523 dbSNP
rs895188871 534 dbSNP
rs970509111 539 dbSNP
rs1182802682 541 dbSNP
rs980218340 542 dbSNP
rs1385744429 543 dbSNP
rs1246534044 548 dbSNP
rs928765561 550 dbSNP
rs960252878 551 dbSNP
rs989003449 552 dbSNP
rs913512380 554 dbSNP
rs1167618223 558 dbSNP
rs1208583015 559 dbSNP
rs1343604547 560 dbSNP
rs947043340 563 dbSNP
rs1297721351 581 dbSNP
rs1227157137 590 dbSNP
rs1362631918 591 dbSNP
rs556852785 604 dbSNP
rs1276366983 612 dbSNP
rs1371994538 615 dbSNP
rs1462101744 616 dbSNP
rs1332923656 617 dbSNP
rs1042742096 621 dbSNP
rs1403488032 622 dbSNP
rs1411607210 631 dbSNP
rs1372434338 635 dbSNP
rs921615576 640 dbSNP
rs931697209 655 dbSNP
rs571692482 657 dbSNP
rs776623588 661 dbSNP
rs1017449591 666 dbSNP
rs1193282246 666 dbSNP
rs1478522167 683 dbSNP
rs776470794 691 dbSNP
rs1053380 694 dbSNP
rs866453683 695 dbSNP
rs761454056 696 dbSNP
rs1484339578 698 dbSNP
rs1203871310 699 dbSNP
rs1274686362 699 dbSNP
rs772513597 702 dbSNP
rs1280385395 705 dbSNP
rs1339613705 705 dbSNP
rs367549533 707 dbSNP
rs1295587186 712 dbSNP
rs1308142643 718 dbSNP
rs1229767724 721 dbSNP
rs1004750493 727 dbSNP
rs554278340 733 dbSNP
rs1261464806 737 dbSNP
rs1036273489 745 dbSNP
rs572429101 751 dbSNP
rs1323134679 753 dbSNP
rs866622277 754 dbSNP
rs764946014 763 dbSNP
rs1484149877 765 dbSNP
rs772809446 781 dbSNP
rs994760463 784 dbSNP
rs1352843082 786 dbSNP
rs144367854 791 dbSNP
rs1415277650 798 dbSNP
rs554335121 798 dbSNP
rs970096039 800 dbSNP
rs1189879086 808 dbSNP
rs910180928 813 dbSNP
rs189960936 814 dbSNP
rs1172227496 818 dbSNP
rs943023449 840 dbSNP
rs1002001182 842 dbSNP
rs575792503 857 dbSNP
rs1238719102 861 dbSNP
rs35305412 875 dbSNP
rs945169182 875 dbSNP
rs1035802988 884 dbSNP
rs1177522962 887 dbSNP
rs1361259026 890 dbSNP
rs960469079 898 dbSNP
rs183291319 905 dbSNP
rs906407452 910 dbSNP
rs114373117 921 dbSNP
rs576787120 923 dbSNP
rs1407934971 924 dbSNP
rs1371211128 926 dbSNP
rs913482609 946 dbSNP
rs968901052 950 dbSNP
rs978998606 951 dbSNP
rs921572934 954 dbSNP
rs565217047 956 dbSNP
rs1323016459 962 dbSNP
rs931693327 968 dbSNP
rs540652766 976 dbSNP
rs897220911 984 dbSNP
rs75000285 990 dbSNP
rs1482712384 1009 dbSNP
rs1030241575 1011 dbSNP
rs940502701 1012 dbSNP
rs1036159527 1013 dbSNP
rs1210353236 1017 dbSNP
rs1260028217 1018 dbSNP
rs1486165291 1021 dbSNP
rs529747132 1023 dbSNP
rs1226454362 1025 dbSNP
rs1323470544 1027 dbSNP
rs1314911034 1036 dbSNP
rs144506818 1038 dbSNP
rs994727567 1042 dbSNP
rs1045006333 1050 dbSNP
rs879129426 1051 dbSNP
rs905840834 1053 dbSNP
rs1001571776 1056 dbSNP
rs1479864331 1056 dbSNP
rs1320346230 1058 dbSNP
rs987104102 1060 dbSNP
rs759773597 1062 dbSNP
rs914939806 1062 dbSNP
rs964350052 1062 dbSNP
rs960150914 1066 dbSNP
rs1199684940 1068 dbSNP
rs1426896926 1072 dbSNP
rs1399289747 1074 dbSNP
rs966851877 1075 dbSNP
rs1158878535 1078 dbSNP
rs1010278221 1081 dbSNP
rs977906195 1088 dbSNP
rs1422077987 1091 dbSNP
rs765851744 1096 dbSNP
rs1206640022 1097 dbSNP
rs759729660 1099 dbSNP
rs1266027856 1105 dbSNP
rs1220745294 1108 dbSNP
rs1344948136 1116 dbSNP
rs1054943982 1125 dbSNP
rs1276797755 1127 dbSNP
rs968878194 1131 dbSNP
rs60345777 1134 dbSNP
rs1053381 1139 dbSNP
rs897194151 1141 dbSNP
rs994621052 1152 dbSNP
rs1393511859 1157 dbSNP
rs1306036453 1173 dbSNP
rs1354249351 1190 dbSNP
rs577527332 1200 dbSNP
rs1289583416 1211 dbSNP
rs550513122 1212 dbSNP
rs987194641 1219 dbSNP
rs1389226518 1221 dbSNP
rs1190747551 1223 dbSNP
rs911549953 1226 dbSNP
rs1007080533 1229 dbSNP
rs940389427 1230 dbSNP
rs971821540 1238 dbSNP
rs148420142 1239 dbSNP
rs1489849356 1242 dbSNP
rs1289647222 1245 dbSNP
rs930485639 1253 dbSNP
rs1343124878 1254 dbSNP
rs1274276545 1255 dbSNP
rs1468303029 1260 dbSNP
rs1045372568 1262 dbSNP
rs1333131965 1269 dbSNP
rs186496512 1274 dbSNP
rs1344223757 1278 dbSNP
rs937334659 1288 dbSNP
rs372699034 1292 dbSNP
rs1441994831 1296 dbSNP
rs1057091547 1301 dbSNP
rs374786181 1302 dbSNP
rs754237575 1303 dbSNP
rs572528572 1304 dbSNP
rs1425331098 1311 dbSNP
rs1010255328 1319 dbSNP
rs1325630988 1327 dbSNP
rs927737624 1329 dbSNP
rs1479404765 1331 dbSNP
rs190488029 1338 dbSNP
rs1253964352 1343 dbSNP
rs1184435585 1349 dbSNP
rs1483384820 1361 dbSNP
rs1441754104 1368 dbSNP
rs762651720 1373 dbSNP
rs757525611 1381 dbSNP
rs1194256768 1385 dbSNP
rs566205580 1388 dbSNP
rs1347449783 1393 dbSNP
rs758216537 1393 dbSNP
rs1256930537 1396 dbSNP
rs1377350670 1402 dbSNP
rs904688812 1407 dbSNP
rs1233055417 1408 dbSNP
rs1322025088 1409 dbSNP
rs536357365 1412 dbSNP
rs1290678103 1413 dbSNP
rs575858135 1420 dbSNP
rs11539705 1431 dbSNP
rs1000405115 1437 dbSNP
rs1312798145 1440 dbSNP
rs990602466 1441 dbSNP
rs1358680757 1451 dbSNP
rs1029657007 1470 dbSNP
rs916450970 1473 dbSNP
rs1397390170 1476 dbSNP
rs1402535315 1480 dbSNP
rs1302035550 1483 dbSNP
rs1291422397 1492 dbSNP
rs1468099537 1494 dbSNP
rs562990847 1501 dbSNP
rs1159741165 1504 dbSNP
rs941272708 1508 dbSNP
rs988138136 1511 dbSNP
rs554596924 1512 dbSNP
rs961724196 1513 dbSNP
rs538429033 1514 dbSNP
rs1238458269 1515 dbSNP
rs1459344926 1516 dbSNP
rs1182165040 1517 dbSNP
rs1460210861 1524 dbSNP
rs780243989 1535 dbSNP
rs575853880 1549 dbSNP
rs1229513023 1561 dbSNP
rs971787451 1562 dbSNP
rs1445776559 1571 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000367723.4 | 3UTR | UGCCAUUAGAAACUGUGAAUUUCCAAAUAAAUCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
116 hsa-miR-3942-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT093395 TMA16 translation machinery associated 16 homolog 2 2
MIRT134018 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT194942 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT265807 NOTCH2 notch 2 2 2
MIRT287615 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT444196 SESN3 sestrin 3 2 2
MIRT444480 UBN2 ubinuclein 2 2 2
MIRT446589 FBXO40 F-box protein 40 2 2
MIRT450501 ALPK3 alpha kinase 3 2 2
MIRT455182 AGTRAP angiotensin II receptor associated protein 2 2
MIRT455446 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT456385 KLHL12 kelch like family member 12 2 2
MIRT460303 FLCN folliculin 2 2
MIRT461247 COX10 COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor 2 6
MIRT467948 SLC16A1 solute carrier family 16 member 1 2 2
MIRT468007 SIX4 SIX homeobox 4 2 2
MIRT468211 SGK1 serum/glucocorticoid regulated kinase 1 2 2
MIRT470635 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT471785 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT473557 MATR3 matrin 3 2 2
MIRT475415 ICK intestinal cell kinase 2 2
MIRT476265 GNAL G protein subunit alpha L 2 6
MIRT477135 FAM107B family with sequence similarity 107 member B 2 6
MIRT478433 DAZAP2 DAZ associated protein 2 2 2
MIRT479050 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 8
MIRT480872 BDNF-AS BDNF antisense RNA 2 2
MIRT484229 CLDN1 claudin 1 2 2
MIRT485055 SUCO SUN domain containing ossification factor 2 2
MIRT489871 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT492411 SCARB2 scavenger receptor class B member 2 2 2
MIRT499682 KCTD2 potassium channel tetramerization domain containing 2 2 4
MIRT505969 RAB11FIP1 RAB11 family interacting protein 1 2 4
MIRT507708 CNIH cornichon family AMPA receptor auxiliary protein 1 2 4
MIRT511878 GID4 GID complex subunit 4 homolog 2 6
MIRT513411 RTP4 receptor transporter protein 4 2 2
MIRT519873 ZFP30 ZFP30 zinc finger protein 2 4
MIRT520703 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT522890 KCNN3 potassium calcium-activated channel subfamily N member 3 2 6
MIRT523781 FAM63B MINDY lysine 48 deubiquitinase 2 2 2
MIRT523950 DYNLT1 dynein light chain Tctex-type 1 2 4
MIRT526894 ATP6V0E2 ATPase H+ transporting V0 subunit e2 2 2
MIRT529167 CCDC25 coiled-coil domain containing 25 2 2
MIRT529703 ZBTB49 zinc finger and BTB domain containing 49 2 2
MIRT530359 PCSK1 proprotein convertase subtilisin/kexin type 1 2 2
MIRT530595 C7orf33 chromosome 7 open reading frame 33 2 4
MIRT531528 CCT6A chaperonin containing TCP1 subunit 6A 2 2
MIRT531992 BARD1 BRCA1 associated RING domain 1 2 2
MIRT539547 AAK1 AP2 associated kinase 1 2 2
MIRT547757 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT549059 CAMSAP1 calmodulin regulated spectrin associated protein 1 2 2
MIRT549836 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 2
MIRT552698 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 2
MIRT554318 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT556358 MAF MAF bZIP transcription factor 2 2
MIRT557772 FRS2 fibroblast growth factor receptor substrate 2 2 2
MIRT558795 CHEK2 checkpoint kinase 2 2 2
MIRT561367 UBXN2B UBX domain protein 2B 2 2
MIRT561673 RAPGEF2 Rap guanine nucleotide exchange factor 2 2 2
MIRT567898 CSNK1A1 casein kinase 1 alpha 1 2 2
MIRT568456 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT568838 NBPF12 NBPF member 12 2 2
MIRT568846 VPS53 VPS53, GARP complex subunit 2 2
MIRT568856 NBPF1 NBPF member 1 2 2
MIRT568888 NBPF15 NBPF member 15 2 2
MIRT569331 CDC5L cell division cycle 5 like 2 2
MIRT569388 NBPF11 NBPF member 11 2 2
MIRT569398 NBPF14 NBPF member 14 2 2
MIRT569644 NBPF10 NBPF member 10 2 2
MIRT571582 TROVE2 TROVE domain family member 2 2 2
MIRT573027 NBPF3 NBPF member 3 2 2
MIRT573293 UFM1 ubiquitin fold modifier 1 2 2
MIRT608814 SEPT6 septin 6 2 6
MIRT609046 BACH2 BTB domain and CNC homolog 2 2 6
MIRT609517 RAB3IP RAB3A interacting protein 2 2
MIRT611861 SRRM4 serine/arginine repetitive matrix 4 2 2
MIRT612174 EMC3 ER membrane protein complex subunit 3 2 2
MIRT612714 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT613305 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 4
MIRT616357 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT632424 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT636005 SAMD15 sterile alpha motif domain containing 15 2 2
MIRT636534 FAM126B family with sequence similarity 126 member B 2 2
MIRT637275 FGFR1OP FGFR1 oncogene partner 2 2
MIRT639131 ZNF726 zinc finger protein 726 2 2
MIRT641257 C8orf46 chromosome 8 open reading frame 46 2 2
MIRT642930 KRTAP5-9 keratin associated protein 5-9 2 2
MIRT644018 NUCB1 nucleobindin 1 2 2
MIRT645021 MAGEB4 MAGE family member B4 2 2
MIRT646790 EVC2 EvC ciliary complex subunit 2 2 2
MIRT647338 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT647975 PDE12 phosphodiesterase 12 2 2
MIRT650610 NEK4 NIMA related kinase 4 2 2
MIRT651052 ZNF579 zinc finger protein 579 2 2
MIRT651593 WDFY2 WD repeat and FYVE domain containing 2 2 2
MIRT652785 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT656450 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT660086 BTD biotinidase 2 2
MIRT661398 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT661759 MICA MHC class I polypeptide-related sequence A 2 2
MIRT666402 SH3D19 SH3 domain containing 19 2 2
MIRT668362 FGD4 FYVE, RhoGEF and PH domain containing 4 2 2
MIRT668895 CREG2 cellular repressor of E1A stimulated genes 2 2 2
MIRT669329 BSND barttin CLCNK type accessory beta subunit 2 2
MIRT672369 PDPK1 3-phosphoinositide dependent protein kinase 1 2 2
MIRT686261 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 2
MIRT695571 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT701959 MINK1 misshapen like kinase 1 2 2
MIRT702322 KMT2A lysine methyltransferase 2A 2 2
MIRT705209 BRWD1 bromodomain and WD repeat domain containing 1 2 2
MIRT713949 KCTD6 potassium channel tetramerization domain containing 6 2 2
MIRT717082 EBF4 early B-cell factor 4 2 2
MIRT717896 COPS8 COP9 signalosome subunit 8 2 2
MIRT721043 TRIM67 tripartite motif containing 67 2 2
MIRT722194 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT722782 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT725412 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3942-3p Osimertinib 71496458 NSC779217 approved resistant Low Non-Small Cell Lung Cancer tissue
hsa-miR-3942-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3942-3p Neoadjuvant chemotherapy resistant tissue (breast cancer)

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