miRTarBase - #MIRT486539


—
pre-miRNA Information
pre-miRNA hsa-mir-4419b   
Genomic Coordinates chr12: 128244506 - 128244573
Description Homo sapiens miR-4419b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4419b
Sequence 42| GAGGCUGAAGGAAGAUGG |59
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CLCN7   
Synonyms CLC-7, CLC7, OPTA2, OPTB4, PPP1R63
Description chloride voltage-gated channel 7
Transcript NM_001114331   
Other Transcripts NM_001287   
Expression
Putative miRNA Targets on CLCN7
3'UTR of CLCN7
(miRNA target sites are highlighted)		 
>CLCN7|NM_001114331|3'UTR
   1 GGCCCAGCCCTGCCCATAATGGGCACTGGCGCTGGCACCCCGGCCCTTCTGCATTTCCTCCCGGAGTCACTGGTTTCTCG
  81 GCCCAAACCATGCTCCCCAGCAGTGGCAATGGCGAGCACCCTGCAGCTGGGCGGGCAGGCGGCAGGCGCGGAACTGACCC
 161 TCTCGCGGGACTGACCCTGTTGTGGGCAGTGGTCTCCCCCCTTGGCGCCTCCTTGCGCAGGCCCAGCCTCCACTCTCCTC
 241 GTCTAGGTTTCTTTACCTCCAGGGATCAGCTGTGTGTGTGTGACCTCCCTACCGGGCTATCGGCCTCTTGGGAGCCAGCG
 321 GCAGGGCCGGCACCTGCGTGCCTGTGCCCGTGTGCGTGAGACAGAGCCCTTGCCCCTGCTGCTGCCCCGAGGGCTGCCCT
 401 GCCCTGGAAGGGCCCCTCTGCCTCCACACCAGTGGAGTCTTCGAGACTTGGGAGCTGCTTGGCCTCATTTTCAGCCATGA
 481 GCAGACGGCCTGTGGTCCCTGGGCCTGAGGCACGGACTCGTAGCACCAGGGTTTGGAGGCTGCGACCGCCCCGGAGAGCA
 561 GCTTCACACTGGCGCCACAGAGGAGCCCCACGTGCACTCCCCGGCCTGCATCCGGCTTGGGTACACAGGCCCAGAGGACT
 641 GGGGTGACTCACGGGCCCTGTGCTGTGATGTTGAGAGCTGAGAAAAACCTCCAAGGCCCTGAGCCCCATGCCCAGCCCTG
 721 CCTTGGTCCCCCAACCCCCAGAGCTTGGAGTCTGGGCCCCACACCCAGCCCTGCCTTGGTCCCTGAGCCTCAGAGCGTGG
 801 AATTGCTGCCCTGTGGACACTGGCTGGGAAGGCAGGTCTTCCCCTAGCACATGGGGACCCCGGCCTCGAGGGTGACCTCC
 881 CTACCCCGCCCCTGCCAGCCACCAAGCGCAGGTGCAGCGGGGGCCAGACTCCTGCCGGCCTCAGAGGACACCTGGCCCAG
 961 CACAGGCAGCTAGAAGGGCCGGTGGGCACCGGGGCCGGGAAGCCCCCACCTCACCACCTGAGGGCCCCTGGGAGGCTCCT
1041 CTGGCCTGGCTGGGCTGGGTCTGGGGCCGCCACAGGCCCCTCACGGGGCGGCAGAGGCAACTTCAGTGTCCCTGTTAGAG
1121 CAACACGGGTCCCTCCGTGGGGGGCTGGGTGCGGCCCCCTGCCGTGTATTTCCTCCCCAGGGAGTGGGGCCTCCCCGGGA
1201 GCTGACGCCACCACCCTGCTTAGCCCTCACAGGGCCCCAAGGTGTCCGAGTGTGTTGGGTCTGAACGCGAAATAAAGAAA
1281 TCCTCTCAGCCCGCCTTTGCCAGCGTCGTCCCTCCCACCCCACCCAGACCACGTCCAACAGCCTGGGACTTTCGGGACCC
1361 TGGGGTCGGGGCACCGTGTGGAGTGAGAAAGGCGTGAAAGACAGCGGCTGCGGCCACCCAGGGCACCAGCCACATCCTCT
1441 TCCTCGTCCCCGCCCCTCAGCCTCCCTCCTCTGGCTCCTGGCTGGTGGGTCTGGGGGCAAGGCAGAGGCGCTCCAGGTGG
1521 AGGGGGGCGGGCCGGGGTGCCCACGCTGGGGTGACGCAAGAAGAAAACTCCCGGGCCTCAGAGTCGGCGCCGGAAACCTA
1601 GGTCTGGGTTTCCCTCGTGGTGGTTGTGTACTGAGGACCTGGAAGTGATCATATTTTGGATATATTCGGTTAAATAAAAT
1681 CAGCGGTTAGGATTCACAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gguagaaGGAAGUCGGAg 5'
                 || ||||||| 
Target 5' tccccgcCCCTCAGCCTc 3'
 1447 - 1464 147.00 -17.50
2 
miRNA  3' gguagaAGGA-AGUCGGag 5'
                |||| ||||||  
Target 5' aagaaaTCCTCTCAGCCcg 3'
 1275 - 1293 132.00 -13.10
3 
miRNA  3' gguAGAAGGAAGUCGGag 5'
             || | :|||||||  
Target 5' gccTCAT-TTTCAGCCat 3'
 462 - 478 130.00 -12.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
886292 9 ClinVar
257947 19 ClinVar
886291 24 ClinVar
317941 57 ClinVar
886290 89 ClinVar
317940 130 ClinVar
886289 132 ClinVar
884262 135 ClinVar
884261 216 ClinVar
317939 228 ClinVar
317938 241 ClinVar
884260 262 ClinVar
317937 355 ClinVar
884259 359 ClinVar
317936 379 ClinVar
317935 388 ClinVar
317934 396 ClinVar
317933 414 ClinVar
317932 496 ClinVar
888485 510 ClinVar
888484 530 ClinVar
317931 543 ClinVar
317930 592 ClinVar
317929 614 ClinVar
317928 627 ClinVar
887233 632 ClinVar
887232 671 ClinVar
317927 717 ClinVar
317926 735 ClinVar
317925 797 ClinVar
317924 886 ClinVar
317923 887 ClinVar
317922 990 ClinVar
886229 996 ClinVar
886228 1017 ClinVar
886227 1026 ClinVar
886226 1085 ClinVar
317920 1145 ClinVar
317921 1145 ClinVar
317919 1157 ClinVar
317918 1176 ClinVar
885324 1180 ClinVar
317917 1189 ClinVar
885323 1215 ClinVar
317916 1248 ClinVar
885322 1289 ClinVar
317915 1293 ClinVar
317914 1297 ClinVar
888426 1330 ClinVar
317913 1332 ClinVar
888425 1368 ClinVar
317912 1389 ClinVar
317911 1403 ClinVar
317910 1421 ClinVar
317909 1452 ClinVar
317908 1491 ClinVar
317907 1498 ClinVar
887171 1572 ClinVar
887170 1573 ClinVar
317906 1589 ClinVar
887169 1607 ClinVar
887168 1623 ClinVar
317905 1625 ClinVar
317904 1626 ClinVar
317903 1645 ClinVar
886153 1667 ClinVar
317902 1685 ClinVar
COSN28164978 6 COSMIC
COSN30122838 46 COSMIC
COSN31560119 113 COSMIC
COSN24833880 179 COSMIC
COSN20073277 206 COSMIC
COSN30732799 207 COSMIC
COSN31975183 212 COSMIC
COSN24313806 240 COSMIC
COSN26957501 271 COSMIC
COSN23058433 287 COSMIC
COSN32055518 294 COSMIC
COSN32253429 325 COSMIC
COSN8817802 356 COSMIC
COSN27027416 509 COSMIC
COSN20093048 510 COSMIC
COSN6644282 735 COSMIC
COSN8485935 968 COSMIC
COSN17604501 996 COSMIC
COSN6080312 1181 COSMIC
COSN32092220 1400 COSMIC
COSN1183488 1425 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1212234948 2 dbSNP
rs773825294 9 dbSNP
rs1252846135 10 dbSNP
rs746293616 12 dbSNP
rs1312472618 15 dbSNP
rs377124088 16 dbSNP
rs11860968 19 dbSNP
rs1028116858 20 dbSNP
rs1223092969 23 dbSNP
rs1361452118 24 dbSNP
rs771855210 25 dbSNP
rs1448945009 26 dbSNP
rs747601379 30 dbSNP
rs867739286 31 dbSNP
rs778586917 32 dbSNP
rs1408441409 35 dbSNP
rs996591044 36 dbSNP
rs1175587883 38 dbSNP
rs1200967089 40 dbSNP
rs964915035 41 dbSNP
rs754924117 42 dbSNP
rs1407322376 43 dbSNP
rs1389134874 44 dbSNP
rs1162744578 46 dbSNP
rs1300238755 47 dbSNP
rs1019491321 49 dbSNP
rs1454370324 51 dbSNP
rs886051697 57 dbSNP
rs749147014 58 dbSNP
rs368220776 62 dbSNP
rs755846000 63 dbSNP
rs1218314948 68 dbSNP
rs886660784 69 dbSNP
rs1199812568 72 dbSNP
rs1333249516 76 dbSNP
rs1453267071 77 dbSNP
rs563732245 79 dbSNP
rs1208788840 80 dbSNP
rs1350743316 88 dbSNP
rs372232215 89 dbSNP
rs1226225020 97 dbSNP
rs945073586 98 dbSNP
rs1284343639 101 dbSNP
rs1225661775 102 dbSNP
rs1329928230 105 dbSNP
rs1323461403 107 dbSNP
rs757487335 109 dbSNP
rs1387192196 110 dbSNP
rs994819785 113 dbSNP
rs778416836 114 dbSNP
rs1430173820 120 dbSNP
rs1473451608 125 dbSNP
rs1176886885 127 dbSNP
rs561217125 130 dbSNP
rs764192196 132 dbSNP
rs768968043 133 dbSNP
rs1447475331 134 dbSNP
rs1249374686 135 dbSNP
rs1206219470 137 dbSNP
rs1435056780 139 dbSNP
rs547400996 140 dbSNP
rs527452340 141 dbSNP
rs565091497 142 dbSNP
rs1343284357 147 dbSNP
rs934499974 148 dbSNP
rs545083540 149 dbSNP
rs978673361 150 dbSNP
rs1350371020 152 dbSNP
rs947072104 155 dbSNP
rs1203928107 159 dbSNP
rs1328657094 160 dbSNP
rs776669247 161 dbSNP
rs1292582374 162 dbSNP
rs920897845 164 dbSNP
rs777148736 165 dbSNP
rs771800053 166 dbSNP
rs576207292 167 dbSNP
rs965476929 171 dbSNP
rs1353791511 173 dbSNP
rs1411000255 179 dbSNP
rs1468364828 179 dbSNP
rs562621944 183 dbSNP
rs1016290282 185 dbSNP
rs1475709217 186 dbSNP
rs1391869133 187 dbSNP
rs1186198152 190 dbSNP
rs1448335800 192 dbSNP
rs551689683 193 dbSNP
rs542599023 194 dbSNP
rs1394232208 196 dbSNP
rs1243426524 197 dbSNP
rs1211759786 199 dbSNP
rs774184483 200 dbSNP
rs1278385914 201 dbSNP
rs1237263182 202 dbSNP
rs1196685822 203 dbSNP
rs1344938228 206 dbSNP
rs768254023 207 dbSNP
rs1227835024 209 dbSNP
rs1383579465 212 dbSNP
rs1317204515 215 dbSNP
rs528735755 216 dbSNP
rs748883273 217 dbSNP
rs1289736139 219 dbSNP
rs779854652 220 dbSNP
rs756086004 222 dbSNP
rs1026562223 223 dbSNP
rs1250017620 224 dbSNP
rs143364973 228 dbSNP
rs899177207 230 dbSNP
rs1428587158 231 dbSNP
rs1385346554 232 dbSNP
rs998450555 235 dbSNP
rs1443985715 236 dbSNP
rs1022879667 237 dbSNP
rs1471612153 238 dbSNP
rs900908722 240 dbSNP
rs559965660 241 dbSNP
rs1183066370 243 dbSNP
rs1167588422 245 dbSNP
rs1484231893 247 dbSNP
rs535031741 250 dbSNP
rs1336620699 251 dbSNP
rs751751949 254 dbSNP
rs1360737756 256 dbSNP
rs572569244 262 dbSNP
rs893435889 264 dbSNP
rs558738228 267 dbSNP
rs368348780 268 dbSNP
rs1355998152 271 dbSNP
rs1280345881 272 dbSNP
rs1410260597 273 dbSNP
rs1337764817 274 dbSNP
rs1352063178 276 dbSNP
rs779726311 278 dbSNP
rs367705655 283 dbSNP
rs768940839 283 dbSNP
rs938270696 283 dbSNP
rs1249744563 284 dbSNP
rs752825359 290 dbSNP
rs1366052343 291 dbSNP
rs765603311 293 dbSNP
rs760110558 294 dbSNP
rs949610414 297 dbSNP
rs538889913 299 dbSNP
rs1158761509 301 dbSNP
rs1043002900 302 dbSNP
rs374403360 311 dbSNP
rs920948402 317 dbSNP
rs1269621657 318 dbSNP
rs975454994 319 dbSNP
rs1490658524 320 dbSNP
rs972117859 321 dbSNP
rs766816261 323 dbSNP
rs1451086627 325 dbSNP
rs943703388 328 dbSNP
rs755587221 331 dbSNP
rs982547799 337 dbSNP
rs950918330 338 dbSNP
rs1229857717 342 dbSNP
rs761166293 346 dbSNP
rs1026405044 349 dbSNP
rs768419661 350 dbSNP
rs1433733497 353 dbSNP
rs886051696 355 dbSNP
rs953985444 356 dbSNP
rs1465334179 357 dbSNP
rs762306226 359 dbSNP
rs1204457063 362 dbSNP
rs1023162670 363 dbSNP
rs1013357824 366 dbSNP
rs1434349747 368 dbSNP
rs1480961649 374 dbSNP
rs1427926218 375 dbSNP
rs775637701 377 dbSNP
rs753373584 379 dbSNP
rs775081376 381 dbSNP
rs769573664 385 dbSNP
rs1210604358 386 dbSNP
rs965161191 387 dbSNP
rs745852264 388 dbSNP
rs193128748 389 dbSNP
rs556271192 392 dbSNP
rs1388529775 394 dbSNP
rs149057560 396 dbSNP
rs1217431714 401 dbSNP
rs903021510 402 dbSNP
rs1002299038 403 dbSNP
rs886051695 414 dbSNP
rs1258833430 416 dbSNP
rs1360558789 421 dbSNP
rs1489178181 421 dbSNP
rs905428385 422 dbSNP
rs1011512218 427 dbSNP
rs1315479151 428 dbSNP
rs1183860285 438 dbSNP
rs899778304 439 dbSNP
rs1039604983 442 dbSNP
rs1222606525 443 dbSNP
rs1373224822 448 dbSNP
rs567572398 450 dbSNP
rs1411123099 455 dbSNP
rs1362494809 457 dbSNP
rs1459893600 459 dbSNP
rs1363337053 461 dbSNP
rs1047055924 463 dbSNP
rs1302076579 464 dbSNP
rs1403379788 471 dbSNP
rs949678454 472 dbSNP
rs1373804279 474 dbSNP
rs943741265 478 dbSNP
rs897955164 486 dbSNP
rs1036539158 487 dbSNP
rs942084304 495 dbSNP
rs60516531 496 dbSNP
rs1047257623 503 dbSNP
rs1356596303 505 dbSNP
rs1232429826 509 dbSNP
rs527600278 510 dbSNP
rs571420082 513 dbSNP
rs1481164618 514 dbSNP
rs1177054417 517 dbSNP
rs973572267 519 dbSNP
rs542865583 520 dbSNP
rs188481235 530 dbSNP
rs562556695 542 dbSNP
rs542386664 543 dbSNP
rs765947375 544 dbSNP
rs1035657965 547 dbSNP
rs999364830 548 dbSNP
rs967426450 549 dbSNP
rs1021704384 552 dbSNP
rs1011438412 553 dbSNP
rs1389229029 562 dbSNP
rs1379956523 569 dbSNP
rs1229878121 573 dbSNP
rs899665281 574 dbSNP
rs1040058145 575 dbSNP
rs1343037314 583 dbSNP
rs987976974 591 dbSNP
rs184831951 592 dbSNP
rs1184767659 596 dbSNP
rs1243003510 601 dbSNP
rs1443322549 602 dbSNP
rs559911117 603 dbSNP
rs1001971204 613 dbSNP
rs886051694 614 dbSNP
rs1470069825 615 dbSNP
rs1336003243 616 dbSNP
rs780705841 626 dbSNP
rs10903009 627 dbSNP
rs572410653 631 dbSNP
rs751460368 632 dbSNP
rs898113589 633 dbSNP
rs1212473317 636 dbSNP
rs1036529334 639 dbSNP
rs1326110345 640 dbSNP
rs1204784164 641 dbSNP
rs1262895517 642 dbSNP
rs1345717866 644 dbSNP
rs1211096469 648 dbSNP
rs1161208738 651 dbSNP
rs929633612 652 dbSNP
rs919702044 665 dbSNP
rs1427338677 667 dbSNP
rs866824383 669 dbSNP
rs1038084372 670 dbSNP
rs1427445361 671 dbSNP
rs1480881492 676 dbSNP
rs368105820 682 dbSNP
rs887958413 683 dbSNP
rs1458791680 701 dbSNP
rs1344112791 703 dbSNP
rs1434042848 704 dbSNP
rs916047304 708 dbSNP
rs1269736033 709 dbSNP
rs1294772737 710 dbSNP
rs992153993 711 dbSNP
rs1345816690 713 dbSNP
rs886051693 717 dbSNP
rs1321812234 727 dbSNP
rs1050917424 728 dbSNP
rs1185150591 732 dbSNP
rs1485714853 734 dbSNP
rs2294542 735 dbSNP
rs928640715 742 dbSNP
rs545179030 752 dbSNP
rs1271120295 759 dbSNP
rs1321991139 760 dbSNP
rs1198930226 762 dbSNP
rs576256047 767 dbSNP
rs1426980328 777 dbSNP
rs1040411774 783 dbSNP
rs1021757038 789 dbSNP
rs943957066 792 dbSNP
rs1332528534 796 dbSNP
rs1407255432 796 dbSNP
rs886051692 797 dbSNP
rs913847434 803 dbSNP
rs1403989876 809 dbSNP
rs987918347 812 dbSNP
rs760078737 819 dbSNP
rs964226553 820 dbSNP
rs556590821 822 dbSNP
rs1280497507 835 dbSNP
rs1008578275 836 dbSNP
rs891014072 841 dbSNP
rs1294092463 844 dbSNP
rs543930400 853 dbSNP
rs969174957 857 dbSNP
rs1266968795 858 dbSNP
rs1322264821 861 dbSNP
rs993835209 862 dbSNP
rs1232070721 867 dbSNP
rs1468213184 868 dbSNP
rs1405247579 879 dbSNP
rs1013297941 883 dbSNP
rs1385340757 884 dbSNP
rs1050834 886 dbSNP
rs6600146 887 dbSNP
rs370691055 888 dbSNP
rs879705233 888 dbSNP
rs1372090213 891 dbSNP
rs1410166717 899 dbSNP
rs1006496243 902 dbSNP
rs1168544078 906 dbSNP
rs1440688685 907 dbSNP
rs1050622258 908 dbSNP
rs1249074483 912 dbSNP
rs1245252993 914 dbSNP
rs996655674 915 dbSNP
rs901963716 918 dbSNP
rs1243067690 919 dbSNP
rs947768077 921 dbSNP
rs1272067399 923 dbSNP
rs1040757316 925 dbSNP
rs1346432166 929 dbSNP
rs894653387 930 dbSNP
rs1249282058 931 dbSNP
rs1243612415 934 dbSNP
rs1055939882 936 dbSNP
rs192589258 937 dbSNP
rs1299624093 938 dbSNP
rs928925376 940 dbSNP
rs1374268850 949 dbSNP
rs1475558764 950 dbSNP
rs1052283290 955 dbSNP
rs1396253247 957 dbSNP
rs534244443 958 dbSNP
rs1408515934 964 dbSNP
rs1339273963 975 dbSNP
rs866505130 978 dbSNP
rs946064090 980 dbSNP
rs571557062 981 dbSNP
rs1228461970 982 dbSNP
rs761010841 986 dbSNP
rs114884549 990 dbSNP
rs964135524 994 dbSNP
rs1018535341 996 dbSNP
rs1263510385 997 dbSNP
rs1460849866 1002 dbSNP
rs1201652545 1003 dbSNP
rs986677190 1004 dbSNP
rs1428540135 1005 dbSNP
rs1461713190 1011 dbSNP
rs1370917309 1014 dbSNP
rs955383044 1016 dbSNP
rs1430382276 1017 dbSNP
rs1469769771 1019 dbSNP
rs1025552868 1024 dbSNP
rs761591980 1026 dbSNP
rs1382788197 1036 dbSNP
rs898169147 1046 dbSNP
rs1317724810 1048 dbSNP
rs1385173010 1049 dbSNP
rs531513124 1052 dbSNP
rs1011966090 1053 dbSNP
rs1444606650 1054 dbSNP
rs894924462 1059 dbSNP
rs569096645 1064 dbSNP
rs1204107551 1067 dbSNP
rs938901889 1068 dbSNP
rs907357028 1069 dbSNP
rs1270081042 1077 dbSNP
rs774171914 1084 dbSNP
rs1174585279 1085 dbSNP
rs1029571902 1087 dbSNP
rs946239214 1089 dbSNP
rs914592068 1090 dbSNP
rs1358664567 1096 dbSNP
rs990119593 1097 dbSNP
rs901908562 1101 dbSNP
rs1344650210 1102 dbSNP
rs376255129 1106 dbSNP
rs1308873897 1107 dbSNP
rs911351114 1110 dbSNP
rs987283828 1113 dbSNP
rs1238204381 1114 dbSNP
rs376254217 1118 dbSNP
rs1360917893 1119 dbSNP
rs1222788570 1122 dbSNP
rs918382870 1123 dbSNP
rs891761041 1126 dbSNP
rs1054394758 1127 dbSNP
rs936579220 1133 dbSNP
rs972644014 1136 dbSNP
rs962573919 1137 dbSNP
rs1365258145 1139 dbSNP
rs1456571045 1139 dbSNP
rs1299708429 1140 dbSNP
rs146690487 1145 dbSNP
rs1306919340 1146 dbSNP
rs1409277940 1149 dbSNP
rs1016794968 1152 dbSNP
rs1011937287 1153 dbSNP
rs1341196675 1154 dbSNP
rs9921 1157 dbSNP
rs940428925 1158 dbSNP
rs907529654 1160 dbSNP
rs984493643 1163 dbSNP
rs1310024863 1164 dbSNP
rs952375139 1169 dbSNP
rs150325021 1176 dbSNP
rs1365296906 1177 dbSNP
rs370167870 1180 dbSNP
rs1384662984 1181 dbSNP
rs188360039 1182 dbSNP
rs886051691 1189 dbSNP
rs1354910513 1190 dbSNP
rs1461239283 1196 dbSNP
rs565215279 1197 dbSNP
rs1010503801 1206 dbSNP
rs1010245441 1207 dbSNP
rs1313785001 1212 dbSNP
rs893418963 1215 dbSNP
rs1215982007 1216 dbSNP
rs1295770734 1234 dbSNP
rs1054712023 1241 dbSNP
rs373977873 1247 dbSNP
rs371394735 1248 dbSNP
rs1290387815 1254 dbSNP
rs1242635691 1261 dbSNP
rs1482285642 1264 dbSNP
rs1211396609 1266 dbSNP
rs1032972976 1267 dbSNP
rs1168339879 1269 dbSNP
rs550477279 1277 dbSNP
rs747728516 1281 dbSNP
rs1044960912 1282 dbSNP
rs879374511 1283 dbSNP
rs545314491 1285 dbSNP
rs1432203259 1287 dbSNP
rs947968376 1291 dbSNP
rs896286031 1292 dbSNP
rs529027139 1293 dbSNP
rs934046030 1295 dbSNP
rs556488187 1297 dbSNP
rs907647514 1299 dbSNP
rs1278457415 1301 dbSNP
rs1324699801 1304 dbSNP
rs1218112802 1307 dbSNP
rs1462872744 1310 dbSNP
rs1407368193 1317 dbSNP
rs1383459298 1318 dbSNP
rs1485690116 1319 dbSNP
rs1159018353 1325 dbSNP
rs941439 1332 dbSNP
rs930295387 1338 dbSNP
rs1413587672 1352 dbSNP
rs574047404 1353 dbSNP
rs962501039 1354 dbSNP
rs1479938303 1361 dbSNP
rs909841674 1363 dbSNP
rs140066822 1367 dbSNP
rs376131222 1368 dbSNP
rs1200733943 1373 dbSNP
rs1304520483 1374 dbSNP
rs988978882 1375 dbSNP
rs1351285114 1376 dbSNP
rs710900 1389 dbSNP
rs1366179046 1390 dbSNP
rs1003310547 1391 dbSNP
rs1033086552 1393 dbSNP
rs970043936 1394 dbSNP
rs1490573064 1400 dbSNP
rs1197973719 1401 dbSNP
rs886051690 1403 dbSNP
rs1471141796 1405 dbSNP
rs1012156603 1406 dbSNP
rs1406626681 1407 dbSNP
rs1417247579 1410 dbSNP
rs896442497 1411 dbSNP
rs1331093734 1412 dbSNP
rs1020701011 1419 dbSNP
rs886051689 1421 dbSNP
rs1329667815 1424 dbSNP
rs1184860786 1425 dbSNP
rs138851469 1428 dbSNP
rs746018594 1435 dbSNP
rs1048777268 1439 dbSNP
rs1054724158 1446 dbSNP
rs28429525 1448 dbSNP
rs930394724 1449 dbSNP
rs1439083431 1451 dbSNP
rs578092313 1452 dbSNP
rs889814660 1453 dbSNP
rs1039146225 1454 dbSNP
rs1205139828 1460 dbSNP
rs1237563095 1461 dbSNP
rs1051506693 1462 dbSNP
rs933980895 1463 dbSNP
rs918695557 1468 dbSNP
rs1437732153 1477 dbSNP
rs182110116 1479 dbSNP
rs1385276060 1485 dbSNP
rs941230995 1486 dbSNP
rs886051688 1491 dbSNP
rs909684761 1492 dbSNP
rs1411941854 1495 dbSNP
rs1391449537 1497 dbSNP
rs373942084 1498 dbSNP
rs1445188552 1499 dbSNP
rs1338829369 1508 dbSNP
rs990755038 1509 dbSNP
rs538156151 1510 dbSNP
rs1282575913 1511 dbSNP
rs1341729838 1517 dbSNP
rs937899366 1522 dbSNP
rs926142809 1523 dbSNP
rs978834741 1524 dbSNP
rs569034711 1526 dbSNP
rs1022962606 1528 dbSNP
rs1243238549 1528 dbSNP
rs982212047 1528 dbSNP
rs966347506 1529 dbSNP
rs1020751702 1531 dbSNP
rs989197296 1533 dbSNP
rs776898053 1534 dbSNP
rs1241345429 1535 dbSNP
rs1464549570 1536 dbSNP
rs960598455 1542 dbSNP
rs1466253555 1544 dbSNP
rs957530520 1545 dbSNP
rs1034904693 1549 dbSNP
rs1201869091 1552 dbSNP
rs1328471412 1552 dbSNP
rs548912339 1554 dbSNP
rs1004819320 1555 dbSNP
rs780423947 1556 dbSNP
rs1049378395 1557 dbSNP
rs994590555 1558 dbSNP
rs1033574484 1566 dbSNP
rs771120676 1568 dbSNP
rs1221197610 1571 dbSNP
rs539134149 1572 dbSNP
rs778327342 1573 dbSNP
rs890063151 1573 dbSNP
rs566427443 1574 dbSNP
rs1297398057 1575 dbSNP
rs1263196203 1576 dbSNP
rs1447263686 1577 dbSNP
rs944405679 1579 dbSNP
rs1262950891 1582 dbSNP
rs1477013207 1585 dbSNP
rs1179026343 1586 dbSNP
rs546700450 1588 dbSNP
rs532736933 1589 dbSNP
rs563752591 1590 dbSNP
rs189885447 1591 dbSNP
rs998181055 1592 dbSNP
rs531884652 1596 dbSNP
rs187858513 1598 dbSNP
rs386787706 1599 dbSNP
rs926134521 1602 dbSNP
rs941409246 1607 dbSNP
rs948813626 1608 dbSNP
rs570138089 1616 dbSNP
rs1055335679 1617 dbSNP
rs916008227 1619 dbSNP
rs1451036503 1623 dbSNP
rs143409179 1625 dbSNP
rs8767 1626 dbSNP
rs386787705 1627 dbSNP
rs1215462103 1629 dbSNP
rs927892002 1639 dbSNP
rs74002247 1645 dbSNP
rs945033457 1649 dbSNP
rs560362445 1651 dbSNP
rs983335193 1659 dbSNP
rs1238175519 1661 dbSNP
rs780617974 1667 dbSNP
rs989249612 1668 dbSNP
rs957748690 1675 dbSNP
rs1420308731 1679 dbSNP
rs1158122812 1683 dbSNP
rs540753146 1684 dbSNP
rs376387077 1685 dbSNP
rs954235570 1691 dbSNP
rs1017744237 1697 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gguagaAGGAAGUCGGag 5'
                ||| ||: ||  
Target 5' ------UCC-UCGUCCcc 3'
 		1 - 11
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000448525.1 | 3UTR | UCCUCGUCCCCGCCCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
390 hsa-miR-4419b Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061343 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT072743 GLCE glucuronic acid epimerase 2 2
MIRT180549 TXNIP thioredoxin interacting protein 2 2
MIRT186147 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT271044 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT334761 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 6
MIRT443279 TSPAN15 tetraspanin 15 2 2
MIRT447047 ZNF439 zinc finger protein 439 2 2
MIRT447351 KIF6 kinesin family member 6 2 2
MIRT448925 CKS1B CDC28 protein kinase regulatory subunit 1B 2 2
MIRT452899 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453087 SUMF2 sulfatase modifying factor 2 2 2
MIRT454071 SLC35E3 solute carrier family 35 member E3 2 2
MIRT456216 LIX1L limb and CNS expressed 1 like 2 6
MIRT456951 LRP10 LDL receptor related protein 10 2 2
MIRT458025 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT459999 RFT1 RFT1 homolog 2 2
MIRT460046 CDCP1 CUB domain containing protein 1 2 2
MIRT460982 STK17B serine/threonine kinase 17b 2 2
MIRT464405 URM1 ubiquitin related modifier 1 2 2
MIRT466256 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 2
MIRT466536 TBXA2R thromboxane A2 receptor 2 2
MIRT470922 PLD5 phospholipase D family member 5 2 8
MIRT472835 MTMR10 myotubularin related protein 10 2 6
MIRT473352 MEMO1 mediator of cell motility 1 2 2
MIRT475504 HSP90B1 heat shock protein 90 beta family member 1 2 2
MIRT478862 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT480898 BCL9L B-cell CLL/lymphoma 9 like 2 2
MIRT482686 NXN nucleoredoxin 2 4
MIRT484128 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT486172 TLE3 transducin like enhancer of split 3 2 4
MIRT486539 CLCN7 chloride voltage-gated channel 7 2 2
MIRT486588 ZNF619 zinc finger protein 619 2 2
MIRT495475 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT495536 TXNRD2 thioredoxin reductase 2 2 2
MIRT495566 UNC5C unc-5 netrin receptor C 2 2
MIRT495719 PADI1 peptidyl arginine deiminase 1 2 2
MIRT495890 CLOCK clock circadian regulator 2 2
MIRT495932 SLC7A5P2 solute carrier family 7 member 5 pseudogene 2 2 2
MIRT496026 ZBED3 zinc finger BED-type containing 3 2 2
MIRT496216 PAX6 paired box 6 2 2
MIRT496349 VAMP1 vesicle associated membrane protein 1 2 2
MIRT496354 PPY pancreatic polypeptide 2 2
MIRT496400 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT496416 PARVB parvin beta 2 2
MIRT496458 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 2 2
MIRT496519 GINS2 GINS complex subunit 2 2 2
MIRT496562 SLC39A9 solute carrier family 39 member 9 2 2
MIRT498605 KRT8 keratin 8 2 2
MIRT503434 SLC25A45 solute carrier family 25 member 45 2 6
MIRT503573 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT503847 ATP13A4 ATPase 13A4 2 4
MIRT504247 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2 4
MIRT505606 SLC35F1 solute carrier family 35 member F1 2 2
MIRT507749 CERS2 ceramide synthase 2 2 4
MIRT508411 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508508 RSRC1 arginine and serine rich coiled-coil 1 2 6
MIRT508944 AK4 adenylate kinase 4 2 4
MIRT509460 ZNF587 zinc finger protein 587 2 6
MIRT509862 ZNF641 zinc finger protein 641 2 4
MIRT511397 IKZF3 IKAROS family zinc finger 3 2 6
MIRT512517 BTBD19 BTB domain containing 19 2 2
MIRT513507 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 6
MIRT514155 TMEM145 transmembrane protein 145 2 4
MIRT514486 SLPI secretory leukocyte peptidase inhibitor 2 4
MIRT514521 SHISA9 shisa family member 9 2 2
MIRT514970 KLLN killin, p53-regulated DNA replication inhibitor 2 4
MIRT515030 IRAK4 interleukin 1 receptor associated kinase 4 2 6
MIRT515963 C9orf156 tRNA methyltransferase O 2 2
MIRT516092 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT517223 PRIM1 DNA primase subunit 1 2 4
MIRT517459 PEX26 peroxisomal biogenesis factor 26 2 4
MIRT517790 EFCAB11 EF-hand calcium binding domain 11 2 2
MIRT517979 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT519458 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT519599 ZNF805 zinc finger protein 805 2 2
MIRT520339 UBXN2A UBX domain protein 2A 2 2
MIRT521345 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT521571 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT523382 GSG2 histone H3 associated protein kinase 2 8
MIRT524106 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT524886 ARHGAP11A Rho GTPase activating protein 11A 2 4
MIRT528772 CD1D CD1d molecule 2 2
MIRT530665 TRIM56 tripartite motif containing 56 2 2
MIRT531107 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT531575 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT535173 PLEKHB2 pleckstrin homology domain containing B2 2 4
MIRT544168 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT550582 SLC2A5 solute carrier family 2 member 5 2 2
MIRT551039 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT551295 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551339 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT552092 SLFN12L schlafen family member 12 like 2 6
MIRT555403 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT557087 HOXB3 homeobox B3 2 2
MIRT559388 ATP11C ATPase phospholipid transporting 11C 2 2
MIRT560305 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT561028 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT562460 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT562982 PARK7 Parkinsonism associated deglycase 2 2
MIRT563548 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT564412 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT569437 PCGF3 polycomb group ring finger 3 2 2
MIRT572097 EXOC8 exocyst complex component 8 2 2
MIRT575571 Cd99 CD99 antigen 2 2
MIRT575789 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT576975 Lmtk2 lemur tyrosine kinase 2 2 2
MIRT610864 ARSA arylsulfatase A 2 2
MIRT614061 NTPCR nucleoside-triphosphatase, cancer-related 2 2
MIRT614141 THAP1 THAP domain containing 1 2 6
MIRT615235 BROX BRO1 domain and CAAX motif containing 2 2
MIRT617429 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT618882 MBL2 mannose binding lectin 2 2 2
MIRT618984 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619196 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620323 AQP6 aquaporin 6 2 2
MIRT621960 STX7 syntaxin 7 2 2
MIRT622057 SSBP2 single stranded DNA binding protein 2 2 2
MIRT624930 FBXW2 F-box and WD repeat domain containing 2 2 2
MIRT624986 ZNF665 zinc finger protein 665 2 4
MIRT625463 ZNF681 zinc finger protein 681 2 4
MIRT625497 SMAD9 SMAD family member 9 2 2
MIRT625599 KLHL23 kelch like family member 23 2 2
MIRT625668 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT625888 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT626161 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT626238 ZNF749 zinc finger protein 749 2 2
MIRT626631 SLC30A6 solute carrier family 30 member 6 2 2
MIRT626994 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627898 OLFML2A olfactomedin like 2A 2 2
MIRT627988 NDRG3 NDRG family member 3 2 2
MIRT628324 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT628549 ZNF701 zinc finger protein 701 2 2
MIRT629464 WIZ widely interspaced zinc finger motifs 2 2
MIRT630527 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT631487 KLHL21 kelch like family member 21 2 2
MIRT631957 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632178 CCL22 C-C motif chemokine ligand 22 2 2
MIRT632282 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT632321 TMEM185B transmembrane protein 185B 2 2
MIRT632853 IGF1 insulin like growth factor 1 2 2
MIRT632862 HSPA2 heat shock protein family A (Hsp70) member 2 2 2
MIRT633322 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT633398 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT633930 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT634785 CBFA2T2 CBFA2/RUNX1 translocation partner 2 2 2
MIRT634851 ABCF1 ATP binding cassette subfamily F member 1 2 2
MIRT636370 OGFRL1 opioid growth factor receptor like 1 2 2
MIRT637219 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT637690 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D 2 2
MIRT639196 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT639599 CD3EAP CD3e molecule associated protein 2 2
MIRT639681 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT640669 ARSK arylsulfatase family member K 2 2
MIRT642377 ZNF581 zinc finger protein 581 2 2
MIRT642403 ZNF556 zinc finger protein 556 2 2
MIRT645079 UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII 2 2
MIRT646475 ZNF669 zinc finger protein 669 2 2
MIRT647325 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT647490 ZNF639 zinc finger protein 639 2 2
MIRT647989 PDE12 phosphodiesterase 12 2 2
MIRT648196 CENPN centromere protein N 2 2
MIRT649006 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT650457 ZNF141 zinc finger protein 141 2 2
MIRT650533 CCDC77 coiled-coil domain containing 77 2 2
MIRT650999 ZNF770 zinc finger protein 770 2 2
MIRT653832 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 4
MIRT655734 NRXN3 neurexin 3 2 2
MIRT657577 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT658610 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT658633 ENAH ENAH, actin regulator 2 2
MIRT659820 CASP16 caspase 16, pseudogene 2 2
MIRT661142 ZNF43 zinc finger protein 43 2 2
MIRT661201 MPPE1 metallophosphoesterase 1 2 2
MIRT661436 MANSC1 MANSC domain containing 1 2 2
MIRT661498 CHMP1B charged multivesicular body protein 1B 2 2
MIRT661682 ZNF623 zinc finger protein 623 2 2
MIRT661796 NLRC3 NLR family CARD domain containing 3 2 2
MIRT661808 NUP85 nucleoporin 85 2 2
MIRT661861 ZNF766 zinc finger protein 766 2 2
MIRT661889 EXOSC6 exosome component 6 2 2
MIRT662291 SLC29A4 solute carrier family 29 member 4 2 2
MIRT662515 ANGPT4 angiopoietin 4 2 2
MIRT662682 LRRC47 leucine rich repeat containing 47 2 2
MIRT662716 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT662834 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT662890 PCDHA6 protocadherin alpha 6 2 2
MIRT663134 ULBP3 UL16 binding protein 3 2 2
MIRT663710 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663869 MUC20 mucin 20, cell surface associated 2 2
MIRT664267 NMUR1 neuromedin U receptor 1 2 2
MIRT664510 POLR3K RNA polymerase III subunit K 2 2
MIRT664659 TRIM65 tripartite motif containing 65 2 2
MIRT664849 HUS1 HUS1 checkpoint clamp component 2 2
MIRT664944 CARD6 caspase recruitment domain family member 6 2 4
MIRT665348 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT665514 UTP15 UTP15, small subunit processome component 2 2
MIRT665648 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT665668 TRAF1 TNF receptor associated factor 1 2 2
MIRT665692 TNPO3 transportin 3 2 2
MIRT665741 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT665850 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT665940 TBC1D19 TBC1 domain family member 19 2 4
MIRT666005 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT666172 SNX27 sorting nexin family member 27 2 4
MIRT666373 SHOX short stature homeobox 2 2
MIRT667004 PDPN podoplanin 2 4
MIRT667185 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667603 LIPC lipase C, hepatic type 2 2
MIRT667828 IRGQ immunity related GTPase Q 2 2
MIRT667862 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668296 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 4
MIRT668463 FAM208A family with sequence similarity 208 member A 2 2
MIRT668580 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT669012 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT669103 CDK19 cyclin dependent kinase 19 2 2
MIRT670073 ZNF783 zinc finger family member 783 2 2
MIRT670326 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT670756 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670964 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT670985 MED17 mediator complex subunit 17 2 2
MIRT671195 ZNF891 zinc finger protein 891 2 2
MIRT672423 SLC10A6 solute carrier family 10 member 6 2 2
MIRT672495 YIPF4 Yip1 domain family member 4 2 2
MIRT672537 MGAM maltase-glucoamylase 2 2
MIRT672749 ZNF585B zinc finger protein 585B 2 4
MIRT673390 ZNF124 zinc finger protein 124 2 2
MIRT673452 ZNF583 zinc finger protein 583 2 2
MIRT673917 DCTN6 dynactin subunit 6 2 2
MIRT673952 ZNF500 zinc finger protein 500 2 2
MIRT674102 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674167 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674206 FUT2 fucosyltransferase 2 2 2
MIRT674452 PURB purine rich element binding protein B 2 4
MIRT674687 PLCE1 phospholipase C epsilon 1 2 2
MIRT674701 TMEM59 transmembrane protein 59 2 2
MIRT674800 NPR1 natriuretic peptide receptor 1 2 4
MIRT675247 MAK male germ cell associated kinase 2 2
MIRT676012 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676374 APTX aprataxin 2 2
MIRT676834 TNFSF15 TNF superfamily member 15 2 2
MIRT678193 CRCP CGRP receptor component 2 2
MIRT678293 PTRH2 peptidyl-tRNA hydrolase 2 2 2
MIRT679532 RAB36 RAB36, member RAS oncogene family 2 2
MIRT679669 RABAC1 Rab acceptor 1 2 2
MIRT679850 GPR75 G protein-coupled receptor 75 2 2
MIRT680533 PRIM2 DNA primase subunit 2 2 2
MIRT680563 ZNF584 zinc finger protein 584 2 2
MIRT680577 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT680849 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT680888 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT680940 EVC EvC ciliary complex subunit 1 2 2
MIRT680964 SLC15A1 solute carrier family 15 member 1 2 4
MIRT681017 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681065 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT681209 ZNF638 zinc finger protein 638 2 2
MIRT681291 RFC2 replication factor C subunit 2 2 2
MIRT681366 BRI3BP BRI3 binding protein 2 2
MIRT681517 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681549 ZNF738 zinc finger protein 738 2 2
MIRT681574 ABHD15 abhydrolase domain containing 15 2 2
MIRT681597 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT681806 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681912 SLC11A2 solute carrier family 11 member 2 2 2
MIRT681953 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682037 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT682111 ITGA3 integrin subunit alpha 3 2 4
MIRT682190 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682247 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682394 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682554 EXOSC2 exosome component 2 2 2
MIRT682665 CASP8 caspase 8 2 2
MIRT683283 ZNF99 zinc finger protein 99 2 2
MIRT683359 SCARF1 scavenger receptor class F member 1 2 2
MIRT683453 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT683596 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT683661 ZNF695 zinc finger protein 695 2 2
MIRT683770 CPE carboxypeptidase E 2 2
MIRT683807 NOTO notochord homeobox 2 2
MIRT684462 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684525 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT684985 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685012 CXorf56 chromosome X open reading frame 56 2 2
MIRT685072 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685115 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685477 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT685831 SLC27A1 solute carrier family 27 member 1 2 2
MIRT686032 UMPS uridine monophosphate synthetase 2 2
MIRT686559 TPM3 tropomyosin 3 2 2
MIRT687287 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT687309 OTUD7B OTU deubiquitinase 7B 2 2
MIRT688085 GLUL glutamate-ammonia ligase 2 2
MIRT688168 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688584 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT688601 CYCS cytochrome c, somatic 2 2
MIRT688921 C11orf84 chromosome 11 open reading frame 84 2 2
MIRT689285 C5AR2 complement component 5a receptor 2 2 2
MIRT689622 AKAP6 A-kinase anchoring protein 6 2 2
MIRT690051 C6orf141 chromosome 6 open reading frame 141 2 2
MIRT690224 C5orf45 MRN complex interacting protein 2 2
MIRT690272 CAMLG calcium modulating ligand 2 2
MIRT690331 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT690480 ZNF33A zinc finger protein 33A 2 2
MIRT690526 ZNF566 zinc finger protein 566 2 2
MIRT690581 MICA MHC class I polypeptide-related sequence A 2 2
MIRT690675 RPF2 ribosome production factor 2 homolog 2 2
MIRT690790 ZNF589 zinc finger protein 589 2 2
MIRT690873 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691142 HJURP Holliday junction recognition protein 2 2
MIRT691158 APOL6 apolipoprotein L6 2 2
MIRT691288 CENPM centromere protein M 2 2
MIRT691435 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT691749 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT691833 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT691885 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT691947 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT692047 PAK1IP1 PAK1 interacting protein 1 2 2
MIRT692668 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT692767 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT692859 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT693122 SCNM1 sodium channel modifier 1 2 2
MIRT693514 MOB3A MOB kinase activator 3A 2 2
MIRT693648 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT693688 MXRA7 matrix remodeling associated 7 2 2
MIRT694078 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT694163 SLC36A2 solute carrier family 36 member 2 2 2
MIRT694262 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT694506 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT694556 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694639 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT694710 CD300LG CD300 molecule like family member g 2 2
MIRT694753 LLGL1 LLGL1, scribble cell polarity complex component 2 2
MIRT694896 ZNF417 zinc finger protein 417 2 2
MIRT695158 BTD biotinidase 2 2
MIRT695275 CD209 CD209 molecule 2 2
MIRT695434 TCF23 transcription factor 23 2 2
MIRT695817 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT696008 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT696345 SLC35D2 solute carrier family 35 member D2 2 2
MIRT696368 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT696533 C3 complement C3 2 2
MIRT696779 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT697075 PSMC4 proteasome 26S subunit, ATPase 4 2 2
MIRT697498 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT697630 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT697931 TXNDC16 thioredoxin domain containing 16 2 2
MIRT697966 TSPYL1 TSPY like 1 2 2
MIRT698237 TMEM216 transmembrane protein 216 2 2
MIRT698643 TES testin LIM domain protein 2 2
MIRT698661 TERF2 telomeric repeat binding factor 2 2 2
MIRT698974 SPAST spastin 2 2
MIRT699047 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699193 SLX4IP SLX4 interacting protein 2 2
MIRT699586 SIKE1 suppressor of IKBKE 1 2 2
MIRT699759 SEPHS1 selenophosphate synthetase 1 2 2
MIRT700350 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT700402 RAB13 RAB13, member RAS oncogene family 2 2
MIRT700418 QDPR quinoid dihydropteridine reductase 2 2
MIRT700546 PTBP2 polypyrimidine tract binding protein 2 2 2
MIRT700774 PLA2G4A phospholipase A2 group IVA 2 2
MIRT700875 PER2 period circadian clock 2 2 2
MIRT700952 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT701077 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT701172 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT701479 NEK9 NIMA related kinase 9 2 2
MIRT701661 MYH9 myosin heavy chain 9 2 2
MIRT701779 MSL2 MSL complex subunit 2 2 2
MIRT702137 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT702494 KIAA1328 KIAA1328 2 2
MIRT703058 GTPBP10 GTP binding protein 10 2 2
MIRT703224 GOLGA3 golgin A3 2 2
MIRT703620 FBXO45 F-box protein 45 2 2
MIRT703657 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT703765 FAM118A family with sequence similarity 118 member A 2 2
MIRT703832 EVI5 ecotropic viral integration site 5 2 2
MIRT703862 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT704664 CLCC1 chloride channel CLIC like 1 2 2
MIRT704812 CDC73 cell division cycle 73 2 2
MIRT705608 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT705625 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT705682 ANKRD40 ankyrin repeat domain 40 2 2
MIRT705813 AKNA AT-hook transcription factor 2 2
MIRT706238 SYT15 synaptotagmin 15 2 2
MIRT706567 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT709657 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710609 ZNF555 zinc finger protein 555 2 2
MIRT711717 IREB2 iron responsive element binding protein 2 2 2
MIRT714122 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT715204 FKTN fukutin 2 2
MIRT718260 ZDHHC8 zinc finger DHHC-type containing 8 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4419b Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Cisplatin + Decitabine resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-4419b Androstenedione+Anastrozole sensitive cell line (MCF-7)

Error report submission