miRTarBase - #MIRT489469


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pre-miRNA Information
pre-miRNA hsa-mir-3180-1   
Genomic Coordinates chr16: 14911220 - 14911313
Description Homo sapiens miR-3180-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-3180-2   
Genomic Coordinates chr16: 16309879 - 16309966
Description Homo sapiens miR-3180-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-3180-3   
Genomic Coordinates chr16: 18402178 - 18402271
Description Homo sapiens miR-3180-3 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3180-3p
Sequence 62| UGGGGCGGAGCUUCCGGAGGCC |83
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLITRK5   
Synonyms LRRC11, bA364G4.2
Description SLIT and NTRK like family member 5
Transcript NM_015567   
Expression
Putative miRNA Targets on SLITRK5
3'UTR of SLITRK5
(miRNA target sites are highlighted)		 
>SLITRK5|NM_015567|3'UTR
   1 AAGCAAAGAAACTCTCTTGGAGCTTTTGCATTTAAAACAAACAAGCAAGCAGACACACACAGTGAACACATTTGATTAAT
  81 TGTGTTGTTTCAACGTTTAGGGTGAAGTGCCTTGGCACGGGATTTCTCAGCTTCGGTGGAAGATACGAAAAGGGTGTGCA
 161 ATTTCCTTTAAAATTTACACGTGGGAAACATTTGTGTAAACTGGGCACATCACTTTCTCTTCTTGCGTGTGGGGCAGGTG
 241 TGGAGAAGGGCTTTAAGGAGGCCAATTTGCTGCGCGGGTGACCTGTGAAAGGTCACAGTCATTTTTGTAGTGGTTGGAAG
 321 TGCTAAGAATGGTGGATGATGGCAGAGCATAGATTCTACTCTTCCTCTTTTGCTTCCTCCCCCTCCCCCGCCCCTGCCCC
 401 ACCTCTCTTTCTCCCCTTTTAAGCCATGGGTGGGTCTAACTGGCTTTTGTGGAGAAATTAGCACACCCCAACTTTAATAG
 481 GAAATTTGTTCTCTTTTTCCGCCCCTCTCCTTCTCTCCTCCCCTCCCCTCCCTTCTCATTCCTTTTCTTTGTTTTTAAAG
 561 GATGTGTTTGTATGCATTCTGGACATTTGAATTAAAAAAAAAGTATTGTGATCCTGTAAAGGATCACCATAGATGTGGAC
 641 AAATCATTAAAATTACAGAGCTATATGATCCATAATTGATTAGTCAAAATAACTTATTGATGAAATATACAAATATTTTA
 721 TTGTAGCACCTATTTTTATATGCACATTTAGCATTCCTCTTTCCTTCACTATTTAGCCTATGATTTTGCAGAGGTGTCAC
 801 ACTGTATTAGGATCTGCATTTCTAAAACTGACGTGGTATCAGGAAGGCATTTTCAATCATTCAAAATGTGGAGAATTTAA
 881 TGGCTAAATCTTTAAAAGCCAATGCAACCCACCCAATTGAATCTGCATTTTCTTTTAAGAAAACAGAGCTGATTGTATCC
 961 CAATGTATTTTAAAAAATAGGGCAATTGATTGGGCCATTCCGAGAGAATTGTTTGCAAGTTTTGGGTTTTATTAGAAAAT
1041 ATTTGAAAGTATTTTTATTAATGAACCAAAATGACATGTTCATTTGACTACTATTGTAGCCGATTTTCGATTGTTTAACC
1121 AAACCCAGTTGCATTTGTACAGATCCACGTGTACTGGCACCTCAGAAGACCAAATCATGGACTGTACAAGTCTCTATACA
1201 ATGTCTTTATCCCTGTGGGCAGCAAGCAATGATGATAATGACAAACAGGATATCTGTAAGATGGGGCTACTGTTGTTACA
1281 GTCTCATATGTATCCCAGCACATGTAATTTTTTAAATAGTTTCTGAATAAACACTTGATAACTATGTCAAAAAAAAAAAA
1361 AAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccGGAGGCCUUCGAGGCGGGGu 5'
            |||||     | ||||||| 
Target 5' ttCCTCCCCCTCCCCCGCCCCt 3'
 374 - 395 152.00 -23.90
2 
miRNA  3' ccggaggccuucGAGGCGGGGu 5'
                      :|||||||| 
Target 5' tttgttctctttTTCCGCCCCt 3'
 485 - 506 146.00 -20.40
3 
miRNA  3' ccGGAGGCCUUCGAGGCGGGGu 5'
            :||||     | || |||| 
Target 5' tcTCTCC----TCCCCTCCCCt 3'
 512 - 529 114.00 -16.31
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM6784381 3 COSMIC
COSN32057485 5 COSMIC
COSN31500345 31 COSMIC
COSN30123900 33 COSMIC
COSN30547984 34 COSMIC
COSN26995653 42 COSMIC
COSN30532914 43 COSMIC
COSN26995654 46 COSMIC
COSN30146996 48 COSMIC
COSN32057089 53 COSMIC
COSN20051706 55 COSMIC
COSN31581887 60 COSMIC
COSN28762467 70 COSMIC
COSN31485487 74 COSMIC
COSN32039505 137 COSMIC
COSN31523281 164 COSMIC
COSN30115991 166 COSMIC
COSN19655563 173 COSMIC
COSN15660908 204 COSMIC
COSN15626311 258 COSMIC
COSN30121629 274 COSMIC
COSN25901065 285 COSMIC
COSN30137303 312 COSMIC
COSN8587868 334 COSMIC
COSN8587869 335 COSMIC
COSN30127843 338 COSMIC
COSN30117785 343 COSMIC
COSN17976346 385 COSMIC
COSN26603316 392 COSMIC
COSN24362553 396 COSMIC
COSN31516924 398 COSMIC
COSN19659496 402 COSMIC
COSN15626312 453 COSMIC
COSN23271260 460 COSMIC
COSN15626313 469 COSMIC
COSN30112414 487 COSMIC
COSN30511023 490 COSMIC
COSN31528572 492 COSMIC
COSN30122142 500 COSMIC
COSN30124605 506 COSMIC
COSN30113213 548 COSMIC
COSN30135371 551 COSMIC
COSN23057607 603 COSMIC
COSN32057360 606 COSMIC
COSN30141644 633 COSMIC
COSN28723018 647 COSMIC
COSN30143904 661 COSMIC
COSN8587870 668 COSMIC
COSN30543358 694 COSMIC
COSN31484280 695 COSMIC
COSN30160771 699 COSMIC
COSN31591047 704 COSMIC
COSN17154284 723 COSMIC
COSN20110873 726 COSMIC
COSN31548436 748 COSMIC
COSN31524192 750 COSMIC
COSN15626314 779 COSMIC
COSN28403819 789 COSMIC
COSN30532637 791 COSMIC
COSN30531431 811 COSMIC
COSN15626315 812 COSMIC
COSN30134993 828 COSMIC
COSN15626316 871 COSMIC
COSN30120690 874 COSMIC
COSN30124645 914 COSMIC
COSN8547151 939 COSMIC
COSN25605271 951 COSMIC
COSN31607473 960 COSMIC
COSN30117610 981 COSMIC
COSN30527793 1005 COSMIC
COSN15626317 1007 COSMIC
COSN30129151 1007 COSMIC
COSN19592494 1041 COSMIC
COSN30126305 1057 COSMIC
COSN5797377 1083 COSMIC
COSN28756396 1110 COSMIC
COSN8587871 1110 COSMIC
COSN19010706 1118 COSMIC
COSN31779016 1120 COSMIC
COSN24937120 1148 COSMIC
COSN31579147 1149 COSMIC
COSN30530409 1160 COSMIC
COSN30123725 1169 COSMIC
COSN30135671 1207 COSMIC
COSN26507834 1218 COSMIC
COSN30110658 1220 COSMIC
COSN32065222 1261 COSMIC
COSN30144094 1299 COSMIC
COSN30530729 1319 COSMIC
COSN31487045 1349 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1417798734 4 dbSNP
rs77866366 8 dbSNP
rs537351293 9 dbSNP
rs1466664671 12 dbSNP
rs991306343 14 dbSNP
rs917168673 15 dbSNP
rs949188070 20 dbSNP
rs971313867 21 dbSNP
rs1393458036 24 dbSNP
rs762111160 26 dbSNP
rs767640228 29 dbSNP
rs773422646 34 dbSNP
rs760896125 35 dbSNP
rs1414192264 45 dbSNP
rs1228739469 46 dbSNP
rs1344019222 56 dbSNP
rs1328271322 57 dbSNP
rs1286365380 70 dbSNP
rs982542176 71 dbSNP
rs1225344930 72 dbSNP
rs1322905917 75 dbSNP
rs1453644204 75 dbSNP
rs1385177738 77 dbSNP
rs918572623 81 dbSNP
rs1289707544 83 dbSNP
rs1366773400 86 dbSNP
rs548949503 128 dbSNP
rs567405547 131 dbSNP
rs534438655 136 dbSNP
rs1053348146 147 dbSNP
rs1048460867 148 dbSNP
rs909930538 152 dbSNP
rs139305230 159 dbSNP
rs1263372899 160 dbSNP
rs993985077 173 dbSNP
rs1026833653 182 dbSNP
rs1265935033 183 dbSNP
rs1205345908 184 dbSNP
rs886486508 186 dbSNP
rs1274211908 191 dbSNP
rs1039843586 195 dbSNP
rs1221308974 199 dbSNP
rs571347942 205 dbSNP
rs1304583478 207 dbSNP
rs1328324717 209 dbSNP
rs1298593887 217 dbSNP
rs571513187 218 dbSNP
rs538665396 227 dbSNP
rs1316321659 240 dbSNP
rs1402071110 244 dbSNP
rs1171382278 245 dbSNP
rs901447076 248 dbSNP
rs959650427 251 dbSNP
rs1374361421 252 dbSNP
rs998435050 257 dbSNP
rs991053334 261 dbSNP
rs556991645 263 dbSNP
rs1185154988 264 dbSNP
rs1025170950 278 dbSNP
rs1277800049 292 dbSNP
rs576048025 311 dbSNP
rs1466329569 312 dbSNP
rs543264615 326 dbSNP
rs1201795095 327 dbSNP
rs902848379 333 dbSNP
rs971318937 335 dbSNP
rs1473248215 336 dbSNP
rs865875331 340 dbSNP
rs1184009659 341 dbSNP
rs923691056 342 dbSNP
rs554867805 346 dbSNP
rs989143903 348 dbSNP
rs1013977698 359 dbSNP
rs1332758537 361 dbSNP
rs573358724 368 dbSNP
rs1160576295 373 dbSNP
rs1168616627 376 dbSNP
rs540387195 380 dbSNP
rs1428572079 382 dbSNP
rs1022713866 385 dbSNP
rs1165133445 387 dbSNP
rs1472994614 390 dbSNP
rs1467778119 391 dbSNP
rs1185152895 394 dbSNP
rs942648065 395 dbSNP
rs1335488863 396 dbSNP
rs1359440074 397 dbSNP
rs1449740775 402 dbSNP
rs1277599192 405 dbSNP
rs1372388733 407 dbSNP
rs1040952508 410 dbSNP
rs1228729168 412 dbSNP
rs1355916649 415 dbSNP
rs1290155965 417 dbSNP
rs1032771742 421 dbSNP
rs1351597593 422 dbSNP
rs1308000647 424 dbSNP
rs867787278 429 dbSNP
rs565073650 431 dbSNP
rs1325107325 433 dbSNP
rs532449842 449 dbSNP
rs1013184774 452 dbSNP
rs759077060 455 dbSNP
rs1412641334 460 dbSNP
rs544247895 464 dbSNP
rs184917883 467 dbSNP
rs971944927 468 dbSNP
rs189422775 472 dbSNP
rs929801018 476 dbSNP
rs951386668 478 dbSNP
rs80232377 479 dbSNP
rs909969350 484 dbSNP
rs886557727 486 dbSNP
rs567362393 487 dbSNP
rs1006307763 489 dbSNP
rs942782330 506 dbSNP
rs1225799107 509 dbSNP
rs1037729346 510 dbSNP
rs895135906 513 dbSNP
rs1183259276 516 dbSNP
rs1227161766 517 dbSNP
rs976015688 517 dbSNP
rs528320915 518 dbSNP
rs1347945793 519 dbSNP
rs1276052258 521 dbSNP
rs1414918737 523 dbSNP
rs1458597999 525 dbSNP
rs192510933 527 dbSNP
rs1158333170 528 dbSNP
rs183785893 529 dbSNP
rs1041997467 531 dbSNP
rs879099903 533 dbSNP
rs1425221551 536 dbSNP
rs1031164516 538 dbSNP
rs1218277731 542 dbSNP
rs903404090 543 dbSNP
rs1267822512 544 dbSNP
rs1207237120 552 dbSNP
rs1326216005 552 dbSNP
rs935668074 561 dbSNP
rs538727733 562 dbSNP
rs1279992961 577 dbSNP
rs957804618 580 dbSNP
rs1366349864 582 dbSNP
rs1272704462 583 dbSNP
rs989175173 585 dbSNP
rs1365480859 587 dbSNP
rs910941166 594 dbSNP
rs557005688 595 dbSNP
rs1353505771 598 dbSNP
rs1360794034 599 dbSNP
rs1176767381 600 dbSNP
rs74969043 603 dbSNP
rs75871884 604 dbSNP
rs764859465 610 dbSNP
rs976405680 615 dbSNP
rs1462971388 617 dbSNP
rs1343629169 622 dbSNP
rs538482672 630 dbSNP
rs1275326513 644 dbSNP
rs1311101577 657 dbSNP
rs149765741 658 dbSNP
rs1230002304 661 dbSNP
rs1342384049 664 dbSNP
rs907030391 671 dbSNP
rs758830608 676 dbSNP
rs1432607630 685 dbSNP
rs1341716460 688 dbSNP
rs1303351120 694 dbSNP
rs1447109439 698 dbSNP
rs189331049 701 dbSNP
rs1047377670 709 dbSNP
rs909698785 715 dbSNP
rs1389752307 717 dbSNP
rs1167006810 719 dbSNP
rs1425910920 721 dbSNP
rs76744313 722 dbSNP
rs371271002 723 dbSNP
rs942123186 725 dbSNP
rs57198481 726 dbSNP
rs1037804402 728 dbSNP
rs895210938 735 dbSNP
rs951934805 743 dbSNP
rs1012258392 746 dbSNP
rs984103410 754 dbSNP
rs906815603 756 dbSNP
rs145726322 757 dbSNP
rs1031613533 760 dbSNP
rs573443376 765 dbSNP
rs975521396 782 dbSNP
rs1410496571 785 dbSNP
rs569036627 791 dbSNP
rs1385960498 795 dbSNP
rs1011004797 796 dbSNP
rs1459579864 798 dbSNP
rs1017981339 805 dbSNP
rs751923118 807 dbSNP
rs963730013 809 dbSNP
rs757678174 810 dbSNP
rs1414804677 812 dbSNP
rs1183603447 820 dbSNP
rs1438782768 823 dbSNP
rs540456313 825 dbSNP
rs1193585510 830 dbSNP
rs1364796337 834 dbSNP
rs951399437 835 dbSNP
rs1290124447 837 dbSNP
rs575977718 840 dbSNP
rs1349806232 841 dbSNP
rs936220851 842 dbSNP
rs1054150412 845 dbSNP
rs1286473775 848 dbSNP
rs558725745 849 dbSNP
rs894131088 869 dbSNP
rs1293206333 870 dbSNP
rs948512483 874 dbSNP
rs536374716 876 dbSNP
rs1276990584 882 dbSNP
rs1357772264 884 dbSNP
rs1045486519 885 dbSNP
rs1472516792 891 dbSNP
rs1410427132 899 dbSNP
rs767226696 900 dbSNP
rs906913617 908 dbSNP
rs1434440682 910 dbSNP
rs993303608 913 dbSNP
rs991283816 914 dbSNP
rs1291228468 916 dbSNP
rs916676740 917 dbSNP
rs148954445 920 dbSNP
rs948157317 922 dbSNP
rs1026079991 935 dbSNP
rs1328331329 937 dbSNP
rs1258931305 943 dbSNP
rs544262393 944 dbSNP
rs1331807404 946 dbSNP
rs544931254 949 dbSNP
rs1385238431 950 dbSNP
rs1367637316 952 dbSNP
rs1017390646 954 dbSNP
rs1449497093 957 dbSNP
rs935298696 958 dbSNP
rs1174879569 964 dbSNP
rs964080567 965 dbSNP
rs1467120051 966 dbSNP
rs894020934 969 dbSNP
rs1190131776 972 dbSNP
rs530447908 973 dbSNP
rs757474935 977 dbSNP
rs1452125394 979 dbSNP
rs1018390292 981 dbSNP
rs899615680 982 dbSNP
rs530067041 984 dbSNP
rs997942539 989 dbSNP
rs1029776445 994 dbSNP
rs1457219270 1009 dbSNP
rs951086605 1012 dbSNP
rs982814778 1013 dbSNP
rs1016878243 1024 dbSNP
rs1029761562 1025 dbSNP
rs1344535650 1027 dbSNP
rs955420378 1032 dbSNP
rs1284402409 1040 dbSNP
rs797011966 1046 dbSNP
rs1298657428 1047 dbSNP
rs1434798381 1057 dbSNP
rs1325111212 1058 dbSNP
rs1336714475 1067 dbSNP
rs1397058298 1072 dbSNP
rs1402141661 1075 dbSNP
rs541840429 1077 dbSNP
rs991347637 1078 dbSNP
rs915747098 1079 dbSNP
rs181987087 1080 dbSNP
rs528370926 1086 dbSNP
rs1388039457 1090 dbSNP
rs990412605 1091 dbSNP
rs982227622 1093 dbSNP
rs1255424823 1096 dbSNP
rs1208776120 1101 dbSNP
rs928001403 1102 dbSNP
rs916106558 1104 dbSNP
rs948421844 1109 dbSNP
rs1045780846 1110 dbSNP
rs928405469 1114 dbSNP
rs1246018715 1115 dbSNP
rs1052358640 1117 dbSNP
rs894091183 1118 dbSNP
rs946951628 1119 dbSNP
rs1308110852 1120 dbSNP
rs1428637783 1125 dbSNP
rs1393907537 1127 dbSNP
rs929037993 1128 dbSNP
rs1047589363 1130 dbSNP
rs1039887910 1131 dbSNP
rs1473026533 1135 dbSNP
rs887610168 1136 dbSNP
rs1005971752 1143 dbSNP
rs746124436 1145 dbSNP
rs900391109 1158 dbSNP
rs1203871774 1159 dbSNP
rs1204547362 1159 dbSNP
rs769819867 1164 dbSNP
rs998726735 1169 dbSNP
rs1292333782 1170 dbSNP
rs1030060104 1172 dbSNP
rs1210780516 1175 dbSNP
rs780122369 1177 dbSNP
rs886834200 1184 dbSNP
rs1230700092 1192 dbSNP
rs1351655215 1198 dbSNP
rs1003894188 1200 dbSNP
rs1016594851 1206 dbSNP
rs34452127 1211 dbSNP
rs1209982089 1218 dbSNP
rs546856335 1220 dbSNP
rs1012833765 1221 dbSNP
rs1405726915 1227 dbSNP
rs1393546691 1235 dbSNP
rs1162534030 1236 dbSNP
rs1022856932 1238 dbSNP
rs1412654256 1250 dbSNP
rs1181505119 1264 dbSNP
rs1468706911 1265 dbSNP
rs1422864688 1266 dbSNP
rs1199929497 1268 dbSNP
rs1451254727 1279 dbSNP
rs1188054057 1284 dbSNP
rs998930917 1287 dbSNP
rs1031881718 1288 dbSNP
rs1158364101 1289 dbSNP
rs1389214886 1290 dbSNP
rs1268095131 1297 dbSNP
rs981660085 1302 dbSNP
rs1370612377 1303 dbSNP
rs1276246367 1306 dbSNP
rs1436670890 1310 dbSNP
rs1322642721 1316 dbSNP
rs1400410128 1317 dbSNP
rs1369807838 1336 dbSNP
rs371993562 1347 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ccGGAGGCCUUCGAGGCGGGGu 5'
            |||:|     |||| |||| 
Target 5' cuCCUUC----UCUCCUCCCC- 3'
 		3 - 19
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000325089.6 | 3UTR | CUCUCCUUCUCUCCUCCCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
66 hsa-miR-3180-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT133792 SKI SKI proto-oncogene 2 2
MIRT146658 MINK1 misshapen like kinase 1 2 4
MIRT441337 C19orf26 CACN beta subunit associated regulatory protein 2 4
MIRT449088 XPO6 exportin 6 2 2
MIRT464967 TULP1 tubby like protein 1 2 6
MIRT471706 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT473252 MIDN midnolin 2 2
MIRT483494 STMN3 stathmin 3 2 4
MIRT483726 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT485684 CCDC64 BICD family like cargo adaptor 1 2 4
MIRT486046 WSCD1 WSC domain containing 1 2 4
MIRT486522 CLCN7 chloride voltage-gated channel 7 2 2
MIRT486779 SESTD1 SEC14 and spectrin domain containing 1 2 4
MIRT486852 DPF1 double PHD fingers 1 2 2
MIRT487035 C10orf55 chromosome 10 open reading frame 55 2 2
MIRT487082 C3orf36 chromosome 3 open reading frame 36 2 2
MIRT487284 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 4
MIRT487992 RXRB retinoid X receptor beta 2 2
MIRT488101 POU3F1 POU class 3 homeobox 1 2 2
MIRT488547 POU3F3 POU class 3 homeobox 3 2 8
MIRT488582 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488757 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT489217 ASCL2 achaete-scute family bHLH transcription factor 2 2 4
MIRT489350 SYNGR1 synaptogyrin 1 2 4
MIRT489385 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT489459 MSC musculin 2 2
MIRT489469 SLITRK5 SLIT and NTRK like family member 5 2 2
MIRT489749 TACC3 transforming acidic coiled-coil containing protein 3 2 2
MIRT490244 MFI2 melanotransferrin 2 2
MIRT490423 VPS51 VPS51, GARP complex subunit 2 4
MIRT490644 FEM1A fem-1 homolog A 2 2
MIRT491977 UNK unkempt family zinc finger 2 2
MIRT492469 RASD1 ras related dexamethasone induced 1 2 4
MIRT492837 NRGN neurogranin 2 2
MIRT492956 NEUROD2 neuronal differentiation 2 2 2
MIRT493002 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT493430 KCNK3 potassium two pore domain channel subfamily K member 3 2 2
MIRT493709 H2AFX H2A histone family member X 2 6
MIRT493886 FAM43A family with sequence similarity 43 member A 2 4
MIRT493955 ENG endoglin 2 2
MIRT500168 MSI1 musashi RNA binding protein 1 2 2
MIRT500196 MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2 4
MIRT500366 ZNF385A zinc finger protein 385A 2 2
MIRT501159 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501698 PCGF3 polycomb group ring finger 3 2 6
MIRT512173 CASP16 caspase 16, pseudogene 2 6
MIRT512237 ATG2A autophagy related 2A 2 6
MIRT512879 PITX3 paired like homeodomain 3 2 2
MIRT531184 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT548362 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 4
MIRT569093 FSCN1 fascin actin-bundling protein 1 2 2
MIRT574133 MARVELD1 MARVEL domain containing 1 2 2
MIRT635542 LEPROTL1 leptin receptor overlapping transcript like 1 2 2
MIRT654098 RSBN1L round spermatid basic protein 1 like 2 2
MIRT664919 BHMT2 betaine--homocysteine S-methyltransferase 2 2 2
MIRT669843 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT670502 LYRM4 LYR motif containing 4 2 2
MIRT670526 SLC9A7 solute carrier family 9 member A7 2 2
MIRT670550 SHISA2 shisa family member 2 2 2
MIRT671031 PCDHB2 protocadherin beta 2 2 2
MIRT695219 SCAMP3 secretory carrier membrane protein 3 2 2
MIRT700129 RNF144B ring finger protein 144B 2 2
MIRT709280 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT712750 GMDS GDP-mannose 4,6-dehydratase 2 2
MIRT720753 FAM193A family with sequence similarity 193 member A 2 2
MIRT724920 VPS18 VPS18, CORVET/HOPS core subunit 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3180 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3180 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3180 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3180 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180 Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (MGC803)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-3180 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-3180 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-3180 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3180-3p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180-3p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180-3p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3180-3p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180-3p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (MGC803)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant Low Gastric Cancer cell line (MGC-803)
hsa-miR-3180-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-3180-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3180-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-3180-3p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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