pre-miRNA Information
pre-miRNA hsa-mir-3192   
Genomic Coordinates chr20: 18470615 - 18470691
Description Homo sapiens miR-3192 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3192-5p
Sequence 10| UCUGGGAGGUUGUAGCAGUGGAA |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs906254403 3 dbSNP
rs554130490 4 dbSNP
rs773140898 6 dbSNP
rs376614009 11 dbSNP
rs899297329 12 dbSNP
rs1330418015 18 dbSNP
rs1402597660 21 dbSNP
rs995052311 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DHX40   
Synonyms ARG147, DDX40, PAD
Description DEAH-box helicase 40
Transcript NM_001166301   
Other Transcripts NM_024612   
Expression
Putative miRNA Targets on DHX40
3'UTR of DHX40
(miRNA target sites are highlighted)
>DHX40|NM_001166301|3'UTR
   1 GGTGGTGAACCCTCCAATTCAGGAAGTGGGAAAAGGAGCCAGGAAATGTGCTTCTACTTTGCCAGTTATTTCAGACAGCA
  81 CTACCAAGAGGAGGTGGTCAGCACTTGTTATTGGCCTATGAACTAAAAGCAAATCAAAGCTCATAAATCAAAGCTCATCA
 161 GTTCCCATAAATGCAGTTGTCAAAGAAAAGATTTGGTTGCCATAGTCATAAGCAATGATACATGAAACCAATGAAAGACA
 241 GTACATGTAATAATATTTTCCTCAGTACAATTTTGCTGGCCTTAACTGGTATCAAACGCTGTCATTGAGATGTTTTCAAA
 321 GAACATTGAGTTGTATTTAATCAGCGTGTACTCCATTTGCATTGAAGCATTAAAAATTATTTTTCTTAAAATCTCTTTAA
 401 GGCCTTCTTGTTGCTGTTAGAATAGTGCTATATATCAGGTATGTGACCATTTATTTCAGAAGGCTGAACATAAGAGGTTT
 481 CTACTCAGCAATACTTAGATGTCTAACTGTTTAATTGCTACAGAGCTTTATAGATATTTAGAGAAAAGACTTAATCAATT
 561 AGTAAATAAAATTGCCTATGGCAGGATTCTTTCTTGAATTAATATTAATCCTTAAATTGATTTTTCTGGGATTATACAAA
 641 TTCCTTTTTATATAAAAGTATATTGTTTAAAACAGTAGCTATAGCCATTAACCAAAGGACAGATGATATATATATATATG
 721 ATATATATATATATATAAGTTCTTTTTTAGCTGTACCTACGTACTTATATCAGCACCATGTATGTAGGTGTGATAGTACT
 801 TTCAAACAGCGCCTCCACCTGGCCTACTCTGTTATTTCCACCTGTTTGGGTAGGGCCATTTAACTTCCATTATGCCAAAC
 881 TTGGGATGGGATTTTCGAAGCAGACAACACTATTTCATCGTGTTTCAAATTGGAACCTTGAGGCTAGTTAGTATCACACT
 961 CAGGCCACACTCAGCACTTGCCCACTCTTGTTTACTGCCTTGTATTCTAGTTATTTGTGTATTTGTCTCCCTCACTAGAT
1041 TATACGCTCCTTGTGGGCAGGGACTGTGTCTTTTTTCATCTTTGTATCTTTCATGCACCTAGCATAGTGCTTTGCACATA
1121 GTAGTCACTCAGTGTTTGTTAAATAAAGCTATTAGTGTCATTAAAATTCAAAAGACAGTAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' aaGGUGACGA-UGUUGGAGGGUcu 5'
            :||  ||| |: | :|||||  
Target 5' aaTCAAAGCTCATCAGTTCCCAta 3'
146 - 169 121.00 -11.40
2
miRNA  3' aaGGUGACGAUGUUGGAGGGUcu 5'
            |||:|    :|| ||:|||  
Target 5' ggCCATT----TAA-CTTCCAtt 3'
854 - 871 114.00 -13.24
3
miRNA  3' aaggugACGAUGUUG-GAGGGUCu 5'
                |||| | || :| |||| 
Target 5' gaaatgTGCTTCTACTTTGCCAGt 3'
43 - 66 113.00 -12.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31556499 39 COSMIC
COSN4906000 49 COSMIC
COSN30638320 53 COSMIC
COSN30464333 58 COSMIC
COSN17077792 65 COSMIC
COSN13735518 103 COSMIC
COSN30466087 103 COSMIC
COSN31548478 186 COSMIC
COSN28688478 271 COSMIC
COSN5418691 450 COSMIC
COSN31551599 577 COSMIC
COSN31597498 777 COSMIC
COSN31595981 872 COSMIC
COSN18715977 920 COSMIC
COSN31489529 941 COSMIC
COSN31489216 962 COSMIC
COSN31595012 1032 COSMIC
COSN26677707 1063 COSMIC
COSN7441267 1100 COSMIC
COSN9319061 1113 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs897594221 3 dbSNP
rs1271060337 8 dbSNP
rs1421186367 11 dbSNP
rs1185657256 13 dbSNP
rs1467718381 15 dbSNP
rs779654894 16 dbSNP
rs1251079263 18 dbSNP
rs746559730 22 dbSNP
rs754512474 27 dbSNP
rs1479891948 29 dbSNP
rs1181718977 43 dbSNP
rs1419133360 44 dbSNP
rs780707304 55 dbSNP
rs1163168220 57 dbSNP
rs748052420 63 dbSNP
rs769709669 64 dbSNP
rs772952298 65 dbSNP
rs749082106 66 dbSNP
rs771329807 69 dbSNP
rs764924133 77 dbSNP
rs1300166915 80 dbSNP
rs574963867 81 dbSNP
rs774685746 82 dbSNP
rs759780577 83 dbSNP
rs542396090 84 dbSNP
rs1235090149 86 dbSNP
rs1272751924 90 dbSNP
rs1291175473 95 dbSNP
rs1320940918 96 dbSNP
rs775572290 98 dbSNP
rs1252775261 99 dbSNP
rs1381650365 100 dbSNP
rs1337050821 105 dbSNP
rs560419973 108 dbSNP
rs764645070 111 dbSNP
rs1452053346 112 dbSNP
rs536785200 119 dbSNP
rs1186479301 120 dbSNP
rs1431610442 125 dbSNP
rs1467132494 131 dbSNP
rs951728222 143 dbSNP
rs1169521346 157 dbSNP
rs1212653627 179 dbSNP
rs1405688085 182 dbSNP
rs146323913 188 dbSNP
rs116594658 191 dbSNP
rs965835426 193 dbSNP
rs1443544806 196 dbSNP
rs927351725 198 dbSNP
rs937468647 200 dbSNP
rs1270754329 201 dbSNP
rs1450484189 206 dbSNP
rs1456852459 213 dbSNP
rs564096346 216 dbSNP
rs1057436738 232 dbSNP
rs531517505 243 dbSNP
rs895852568 245 dbSNP
rs763346495 246 dbSNP
rs1245495836 267 dbSNP
rs1354606322 271 dbSNP
rs1311562193 277 dbSNP
rs1047277844 278 dbSNP
rs1479282771 279 dbSNP
rs1371118993 283 dbSNP
rs1297514423 284 dbSNP
rs766683525 290 dbSNP
rs1351395154 292 dbSNP
rs751901862 298 dbSNP
rs1423611580 302 dbSNP
rs1423320808 305 dbSNP
rs549636456 320 dbSNP
rs1159960123 321 dbSNP
rs1018469335 322 dbSNP
rs756274752 322 dbSNP
rs905458183 327 dbSNP
rs939491092 328 dbSNP
rs1489703983 335 dbSNP
rs1056619458 346 dbSNP
rs1388683881 352 dbSNP
rs1222120673 353 dbSNP
rs372343386 369 dbSNP
rs964445659 379 dbSNP
rs1488757858 380 dbSNP
rs1404769866 384 dbSNP
rs1324274233 394 dbSNP
rs1316410177 404 dbSNP
rs755453222 404 dbSNP
rs1306275814 407 dbSNP
rs1219754020 416 dbSNP
rs1369558905 418 dbSNP
rs1301101194 433 dbSNP
rs1398042088 433 dbSNP
rs1360829042 438 dbSNP
rs1030408471 440 dbSNP
rs1451077425 442 dbSNP
rs1362692750 458 dbSNP
rs1176079252 470 dbSNP
rs568321506 475 dbSNP
rs1340846929 482 dbSNP
rs535323859 487 dbSNP
rs1199175435 498 dbSNP
rs1049324744 499 dbSNP
rs1053130294 502 dbSNP
rs1214711351 503 dbSNP
rs547567950 512 dbSNP
rs1017504579 513 dbSNP
rs965969314 516 dbSNP
rs1313906669 518 dbSNP
rs997866299 519 dbSNP
rs1222715479 522 dbSNP
rs1213693060 524 dbSNP
rs1020134480 543 dbSNP
rs1031489711 549 dbSNP
rs1291374633 549 dbSNP
rs956100413 553 dbSNP
rs565641855 558 dbSNP
rs1302949587 567 dbSNP
rs968617746 569 dbSNP
rs1467086172 574 dbSNP
rs1215033085 579 dbSNP
rs915328359 587 dbSNP
rs1176297177 590 dbSNP
rs1478387353 597 dbSNP
rs967985599 602 dbSNP
rs1488788373 614 dbSNP
rs1191402794 630 dbSNP
rs1428177484 633 dbSNP
rs139597241 635 dbSNP
rs1367002415 642 dbSNP
rs927150797 648 dbSNP
rs781675415 654 dbSNP
rs1472582255 661 dbSNP
rs1261258681 665 dbSNP
rs1202940794 674 dbSNP
rs937418317 677 dbSNP
rs992958070 682 dbSNP
rs1259755700 692 dbSNP
rs926651987 699 dbSNP
rs1297446079 703 dbSNP
rs1469888333 706 dbSNP
rs752279316 706 dbSNP
rs780338300 706 dbSNP
rs1335421077 710 dbSNP
rs917327659 716 dbSNP
rs929956643 720 dbSNP
rs1047115211 721 dbSNP
rs1048768659 721 dbSNP
rs1057154655 721 dbSNP
rs145658581 721 dbSNP
rs778262483 721 dbSNP
rs1167173968 723 dbSNP
rs887540343 724 dbSNP
rs1242619890 733 dbSNP
rs183240600 736 dbSNP
rs941623730 737 dbSNP
rs200115441 743 dbSNP
rs1331935555 744 dbSNP
rs1246553290 752 dbSNP
rs1356741486 754 dbSNP
rs900038572 755 dbSNP
rs996321227 760 dbSNP
rs1030048763 761 dbSNP
rs1032045185 763 dbSNP
rs1327406353 769 dbSNP
rs955857888 772 dbSNP
rs35940483 776 dbSNP
rs1391894436 779 dbSNP
rs576082770 783 dbSNP
rs1165302003 784 dbSNP
rs1009876316 785 dbSNP
rs1285482311 788 dbSNP
rs1350798826 804 dbSNP
rs752893446 811 dbSNP
rs1238624663 812 dbSNP
rs1285850472 816 dbSNP
rs537024775 828 dbSNP
rs1011829712 831 dbSNP
rs144223626 832 dbSNP
rs968586664 836 dbSNP
rs1365504297 842 dbSNP
rs1179568453 855 dbSNP
rs1219317815 857 dbSNP
rs968120305 859 dbSNP
rs1267798292 868 dbSNP
rs980853014 871 dbSNP
rs1442098136 873 dbSNP
rs1188456790 876 dbSNP
rs1240295687 879 dbSNP
rs978686787 883 dbSNP
rs1034136033 888 dbSNP
rs539740069 891 dbSNP
rs993074933 898 dbSNP
rs917318880 907 dbSNP
rs1238980701 910 dbSNP
rs1332112276 911 dbSNP
rs79673346 913 dbSNP
rs756250614 920 dbSNP
rs1365238936 921 dbSNP
rs1298995948 950 dbSNP
rs1421668664 952 dbSNP
rs1012049739 955 dbSNP
rs560687852 960 dbSNP
rs919510346 966 dbSNP
rs572214242 976 dbSNP
rs929463901 978 dbSNP
rs982769490 982 dbSNP
rs778192249 984 dbSNP
rs1421419682 998 dbSNP
rs1170637922 1000 dbSNP
rs1267822114 1007 dbSNP
rs1401186954 1008 dbSNP
rs545854998 1011 dbSNP
rs532172649 1020 dbSNP
rs1281526440 1021 dbSNP
rs1040013387 1029 dbSNP
rs900092720 1040 dbSNP
rs909402701 1042 dbSNP
rs564161687 1043 dbSNP
rs144228958 1046 dbSNP
rs1335715312 1047 dbSNP
rs1051714490 1053 dbSNP
rs1374021073 1065 dbSNP
rs1038836062 1066 dbSNP
rs1402095538 1081 dbSNP
rs901505352 1081 dbSNP
rs1445485698 1085 dbSNP
rs890198159 1085 dbSNP
rs757464506 1089 dbSNP
rs1415089650 1097 dbSNP
rs59018214 1100 dbSNP
rs779739962 1102 dbSNP
rs1178499390 1105 dbSNP
rs1468093204 1131 dbSNP
rs1009963856 1138 dbSNP
rs1309330659 1149 dbSNP
rs1019903582 1158 dbSNP
rs1378350099 1159 dbSNP
rs1476205297 1170 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' aaGGUGACGAUGUUGGAGGgucu 5'
            ||:|  || | :|||||    
Target 5' gcCCGC--CU-CUGCCUCC---- 3'
3 - 18
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000251241.4 | 3UTR | GCGCCCGCCUCUGCCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
HNSC -0.959 0.09 -1.000 0.5 3 Click to see details
167 hsa-miR-3192-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT058548 CTTNBP2NL CTTNBP2 N-terminal like 2 2
MIRT139892 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT207395 MAT2A methionine adenosyltransferase 2A 2 6
MIRT294640 ZNF548 zinc finger protein 548 2 2
MIRT324251 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT441475 BEST3 bestrophin 3 2 2
MIRT445233 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2 2
MIRT446763 ZNF491 zinc finger protein 491 2 2
MIRT451003 EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 2 2
MIRT452436 QDPR quinoid dihydropteridine reductase 2 2
MIRT452582 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT452950 DISC1 disrupted in schizophrenia 1 2 2
MIRT453309 ZNF394 zinc finger protein 394 2 2
MIRT453810 KBTBD12 kelch repeat and BTB domain containing 12 2 2
MIRT454101 TMEM209 transmembrane protein 209 2 2
MIRT456228 LIX1L limb and CNS expressed 1 like 2 4
MIRT456738 TMEM239 transmembrane protein 239 2 2
MIRT456806 SIGLEC14 sialic acid binding Ig like lectin 14 2 4
MIRT457499 SLC35F6 solute carrier family 35 member F6 2 2
MIRT458037 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT459041 ZNF490 zinc finger protein 490 2 2
MIRT459135 FADS6 fatty acid desaturase 6 2 2
MIRT460126 CXCL16 C-X-C motif chemokine ligand 16 2 2
MIRT460506 FAM105A family with sequence similarity 105 member A 2 6
MIRT460944 NOA1 nitric oxide associated 1 2 4
MIRT461101 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462641 PHF5A PHD finger protein 5A 2 2
MIRT463584 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT466567 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT467090 SRRD SRR1 domain containing 2 2
MIRT471093 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT472596 NACC1 nucleus accumbens associated 1 2 2
MIRT473084 MORN4 MORN repeat containing 4 2 2
MIRT475977 GTPBP2 GTP binding protein 2 2 2
MIRT477054 FAM210A family with sequence similarity 210 member A 2 2
MIRT478303 DDX19A DEAD-box helicase 19A 2 4
MIRT478489 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT478500 CYP1B1 cytochrome P450 family 1 subfamily B member 1 2 2
MIRT478858 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT479096 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT479180 CLSPN claspin 2 2
MIRT479215 CLCC1 chloride channel CLIC like 1 2 2
MIRT481176 AVL9 AVL9 cell migration associated 2 6
MIRT483032 KHSRP KH-type splicing regulatory protein 2 4
MIRT485150 RASL10B RAS like family 10 member B 2 2
MIRT486104 SLC7A5 solute carrier family 7 member 5 2 4
MIRT486319 SIPA1 signal-induced proliferation-associated 1 2 2
MIRT489443 IFNLR1 interferon lambda receptor 1 2 2
MIRT489585 SSBP2 single stranded DNA binding protein 2 2 2
MIRT489702 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT490184 TMEM63C transmembrane protein 63C 2 2
MIRT491211 MLLT1 MLLT1, super elongation complex subunit 2 4
MIRT491276 DHX40 DEAH-box helicase 40 2 2
MIRT495162 CNGA2 cyclic nucleotide gated channel alpha 2 2 4
MIRT495222 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT496820 CHRNB2 cholinergic receptor nicotinic beta 2 subunit 2 2
MIRT498602 KRT8 keratin 8 2 2
MIRT500003 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT502065 KRAS KRAS proto-oncogene, GTPase 2 2
MIRT508197 SLC35E1 solute carrier family 35 member E1 2 2
MIRT508477 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT509635 RRP7A ribosomal RNA processing 7 homolog A 2 4
MIRT511039 NRF1 nuclear respiratory factor 1 2 2
MIRT516684 ZNF860 zinc finger protein 860 2 4
MIRT518394 ZNF250 zinc finger protein 250 2 2
MIRT518907 CDC14B cell division cycle 14B 2 2
MIRT520502 TRAM2 translocation associated membrane protein 2 2 6
MIRT521459 RAD51 RAD51 recombinase 2 2
MIRT522354 NCKIPSD NCK interacting protein with SH3 domain 2 4
MIRT522594 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT523267 HIST1H2AE histone cluster 1 H2A family member e 2 2
MIRT523532 GLUL glutamate-ammonia ligase 2 4
MIRT524186 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT526842 PHC1 polyhomeotic homolog 1 2 2
MIRT528729 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT540695 BMP3 bone morphogenetic protein 3 2 2
MIRT544483 TRIM4 tripartite motif containing 4 2 2
MIRT551566 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT563619 ZNF277 zinc finger protein 277 2 2
MIRT564467 SLC35E2 solute carrier family 35 member E2 2 2
MIRT565031 VAV2 vav guanine nucleotide exchange factor 2 2 2
MIRT570294 ARPC3 actin related protein 2/3 complex subunit 3 2 2
MIRT572932 VDAC2 voltage dependent anion channel 2 2 2
MIRT573501 IQSEC3 IQ motif and Sec7 domain 3 2 2
MIRT573675 HES6 hes family bHLH transcription factor 6 2 2
MIRT609619 TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein 2 2
MIRT611966 PKD1 polycystin 1, transient receptor potential channel interacting 2 2
MIRT613930 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT617733 ATCAY ATCAY, caytaxin 2 4
MIRT618878 MBL2 mannose binding lectin 2 2 2
MIRT627590 SHROOM3 shroom family member 3 2 2
MIRT628516 ZNF878 zinc finger protein 878 2 2
MIRT633964 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT634530 NEGR1 neuronal growth regulator 1 2 2
MIRT635455 APOLD1 apolipoprotein L domain containing 1 2 2
MIRT636412 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT639672 PPEF2 protein phosphatase with EF-hand domain 2 2 6
MIRT642667 RGS6 regulator of G protein signaling 6 2 2
MIRT644080 A4GALT alpha 1,4-galactosyltransferase (P blood group) 2 2
MIRT647318 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT647942 RNF152 ring finger protein 152 2 2
MIRT648687 AP1M1 adaptor related protein complex 1 mu 1 subunit 2 2
MIRT648817 ZNF689 zinc finger protein 689 2 2
MIRT650347 TREM1 triggering receptor expressed on myeloid cells 1 2 2
MIRT650374 MOCS3 molybdenum cofactor synthesis 3 2 4
MIRT655935 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT663778 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT664297 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT665842 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT668929 COL9A2 collagen type IX alpha 2 chain 2 2
MIRT669673 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT669907 KIAA0754 KIAA0754 2 4
MIRT670248 TRIM13 tripartite motif containing 13 2 2
MIRT670368 ULBP3 UL16 binding protein 3 2 4
MIRT670642 BVES blood vessel epicardial substance 2 2
MIRT670749 HOOK3 hook microtubule tethering protein 3 2 2
MIRT671184 ZNF891 zinc finger protein 891 2 2
MIRT673946 ZNF500 zinc finger protein 500 2 2
MIRT674682 PLCE1 phospholipase C epsilon 1 2 2
MIRT677912 HIST1H2BN histone cluster 1 H2B family member n 2 2
MIRT678876 FAM118A family with sequence similarity 118 member A 2 2
MIRT679528 RAB36 RAB36, member RAS oncogene family 2 2
MIRT680589 ZNF573 zinc finger protein 573 2 2
MIRT680650 KIAA1456 KIAA1456 2 2
MIRT681149 INTS7 integrator complex subunit 7 2 2
MIRT681177 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT681234 DUSP19 dual specificity phosphatase 19 2 2
MIRT681626 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681643 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT681926 KAT7 lysine acetyltransferase 7 2 2
MIRT682050 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT682156 SMS spermine synthase 2 2
MIRT683555 HAVCR1 hepatitis A virus cellular receptor 1 2 2
MIRT684304 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT684458 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT685986 CCDC77 coiled-coil domain containing 77 2 2
MIRT686782 AZF1 azoospermia factor 1 2 2
MIRT687329 OSMR oncostatin M receptor 2 2
MIRT687629 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT688792 CCNB1 cyclin B1 2 2
MIRT689756 PRR13 proline rich 13 2 2
MIRT690823 SGSM2 small G protein signaling modulator 2 2 2
MIRT691310 ZNF681 zinc finger protein 681 2 2
MIRT692676 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT693508 MOB3A MOB kinase activator 3A 2 2
MIRT694657 C14orf119 chromosome 14 open reading frame 119 2 2
MIRT694889 ZNF417 zinc finger protein 417 2 2
MIRT695740 ZNF117 zinc finger protein 117 2 2
MIRT697101 GPKOW G-patch domain and KOW motifs 2 2
MIRT698968 SPAST spastin 2 2
MIRT700379 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT703930 EPG5 ectopic P-granules autophagy protein 5 homolog 2 2
MIRT706234 SYT15 synaptotagmin 15 2 2
MIRT706494 SEPT6 septin 6 2 2
MIRT710451 BTNL3 butyrophilin like 3 2 2
MIRT711684 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT711997 F9 coagulation factor IX 2 2
MIRT712727 NCAPG2 non-SMC condensin II complex subunit G2 2 2
MIRT713111 TMBIM4 transmembrane BAX inhibitor motif containing 4 2 2
MIRT713156 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT713440 AJAP1 adherens junctions associated protein 1 2 2
MIRT713830 NUP98 nucleoporin 98 2 2
MIRT714979 RAB21 RAB21, member RAS oncogene family 2 2
MIRT717411 ZCCHC24 zinc finger CCHC-type containing 24 2 2
MIRT718433 ZNF85 zinc finger protein 85 2 2
MIRT720575 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT725098 TMEM120B transmembrane protein 120B 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-3192 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3192 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-3192 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3192-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-3192-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-3192-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3192-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3192-5p Platinum 23939 resistant tissue
hsa-miR-3192-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3192-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-3192-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)

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