pre-miRNA Information
pre-miRNA hsa-mir-3179-1   
Genomic Coordinates chr16: 14901508 - 14901591
Description Homo sapiens miR-3179-1 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-2   
Genomic Coordinates chr16: 16300159 - 16300242
Description Homo sapiens miR-3179-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-3   
Genomic Coordinates chr16: 18411894 - 18411977
Description Homo sapiens miR-3179-3 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-4   
Genomic Coordinates chr16: 18494493 - 18494576
Description Homo sapiens miR-3179-4 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-3179
Sequence 52| AGAAGGGGUGAAAUUUAAACGU |73
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1351100204 1 dbSNP
rs1398613616 4 dbSNP
rs1340262765 20 dbSNP
rs1229893475 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SEMA3F   
Synonyms SEMA-IV, SEMA4, SEMAK
Description semaphorin 3F
Transcript NM_004186   
Expression
Putative miRNA Targets on SEMA3F
3'UTR of SEMA3F
(miRNA target sites are highlighted)
>SEMA3F|NM_004186|3'UTR
   1 GGCCAGCTGCCTGTGCCTGCCATGGGCCAGCCTAGCCCTTGTCCCTTTTAATATAAAAGATATATATATATATATATATA
  81 TATAAAATATCTATATTCTATACACACCCTGCCCCTGCAAAGACAGTATTTATTGGTGGGTTGAATATAGCCTGCCTCAG
 161 TGGCAGCATCCTCCAAAACTTAGACCCATGCTGGTCAGAGACGGCAGAAAACAGAGCCTGCCTAACCAGGCCCAGCCAGT
 241 TGGTGGGGCCAGGCCAGGACCACACAGTCCCCAGACTCAGCTGGAAGTCTACCTGCTGGACAGCCTCCGCCAAGATCTAC
 321 AGGACAAAGGGAGGGAGCAAGCCCTACTCGGATGGGGCACGGACTGTCCACCTTTTCTGATGTGTGTTGTCAGCCTGTGC
 401 TGTGGCATAGACATGGATGCGAGGACCACTTTGGAGACTGGGGTGGCCTCAAGAGCACACAGAGAAGGGAAGAAGGGGCC
 481 ATCACAGGATGCCAGCCCCTGCCTGGGTTGGGGGCACTCAGCCACGACCAGCCCCTTCCTGGGTATTTATTCTCTATTTA
 561 TTGGGGATAGGAGAAGAGGCATCCTGCCTGGGTGGGACAGCCTCTTCAGCCCCTTCTCCCCTCCCCGCCTGGCCAGGGCA
 641 GGGCCACCCCACTCTACCTCCTTAGCTTTCCCTGTGCCACTTTGACTCAGAGGCTGGGAGCATAGCAGAGGGGCCAGGCC
 721 CAGGCAGAGCTGACGGGAGGCCCCAGCTCTGAGGGGAGGGGGTCCGTGGTAGAGGCCTGGGGCCGGTAGAGGCTCCCCAG
 801 GGCTCCCTTATGTCCACCACTTCAGGGGATGGGTGTGGATGTAATTAGCTCTGGGGGGCAGTTGGGTAGATGGGTGGGGG
 881 CTCCTGGTGGCCTTCTGCTGCCCAGGCCACAGCCGCCTTTGGGTTCCATCTTGCTAATAAACACTGGCTCTGGGACTAGA
 961 AAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ugcaaauuuaAAGU-GGGGAAGa 5'
                    |||| ||||||| 
Target 5' ggacagcctcTTCAGCCCCTTCt 3'
595 - 617 152.00 -15.40
2
miRNA  3' ugcaaauuuaaaGU-GGGGAAGa 5'
                      || ||||||| 
Target 5' ctcagccacgacCAGCCCCTTCc 3'
517 - 539 142.00 -12.30
3
miRNA  3' ugcaAAUUUAAAGUGGGGAAGa 5'
              ||| : | |||| |||| 
Target 5' tcccTTATG-TCCACCACTTCa 3'
804 - 824 125.00 -8.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN29109745 85 COSMIC
COSN31813219 85 COSMIC
COSN31589948 157 COSMIC
COSN229519 247 COSMIC
COSN20090819 310 COSMIC
COSN28198058 330 COSMIC
COSN31485958 559 COSMIC
COSN31483489 608 COSMIC
COSN28778305 611 COSMIC
COSN20578558 624 COSMIC
COSN31512763 736 COSMIC
COSN23700140 765 COSMIC
COSN31591670 784 COSMIC
COSN1951879 812 COSMIC
COSN16996585 950 COSMIC
COSN16457810 960 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs755520960 3 dbSNP
rs777323151 4 dbSNP
rs755683639 8 dbSNP
rs150672207 9 dbSNP
rs1476888905 10 dbSNP
rs955158633 13 dbSNP
rs998623123 14 dbSNP
rs758942510 18 dbSNP
rs1018163872 20 dbSNP
rs11558285 21 dbSNP
rs973423438 24 dbSNP
rs747331182 31 dbSNP
rs1046959 32 dbSNP
rs1420013816 34 dbSNP
rs1046960 37 dbSNP
rs768955567 38 dbSNP
rs543148563 44 dbSNP
rs1194061636 46 dbSNP
rs1432524177 58 dbSNP
rs1476996064 58 dbSNP
rs1175476079 60 dbSNP
rs1330861833 60 dbSNP
rs1375815358 60 dbSNP
rs1379960466 60 dbSNP
rs1398987225 60 dbSNP
rs1465654023 60 dbSNP
rs148259784 60 dbSNP
rs1491497511 60 dbSNP
rs59949761 60 dbSNP
rs1491108900 61 dbSNP
rs950713961 62 dbSNP
rs952623392 62 dbSNP
rs983888106 64 dbSNP
rs908439766 70 dbSNP
rs908546849 73 dbSNP
rs72205047 75 dbSNP
rs1375426622 82 dbSNP
rs1199338430 84 dbSNP
rs200144707 84 dbSNP
rs992771986 86 dbSNP
rs1045027271 92 dbSNP
rs1308978630 94 dbSNP
rs1431991521 98 dbSNP
rs915714187 101 dbSNP
rs948538869 108 dbSNP
rs1293448934 109 dbSNP
rs976904780 115 dbSNP
rs1395490531 116 dbSNP
rs1400165904 123 dbSNP
rs1356963368 126 dbSNP
rs922768469 146 dbSNP
rs1379689075 151 dbSNP
rs757257202 154 dbSNP
rs1269312818 166 dbSNP
rs1042827610 186 dbSNP
rs1156588794 196 dbSNP
rs1471052307 200 dbSNP
rs1363976665 204 dbSNP
rs1186405974 213 dbSNP
rs1421480346 218 dbSNP
rs904306382 231 dbSNP
rs934330034 234 dbSNP
rs879342730 243 dbSNP
rs139857596 247 dbSNP
rs890144309 249 dbSNP
rs915470956 250 dbSNP
rs1216155430 252 dbSNP
rs1278058491 274 dbSNP
rs1485340582 283 dbSNP
rs1214845773 290 dbSNP
rs1009532991 291 dbSNP
rs1259715781 292 dbSNP
rs1280295446 293 dbSNP
rs1244352313 297 dbSNP
rs1017818530 309 dbSNP
rs550405002 310 dbSNP
rs995001871 314 dbSNP
rs1373945015 315 dbSNP
rs1027683800 320 dbSNP
rs950829557 321 dbSNP
rs983576236 322 dbSNP
rs1415528645 330 dbSNP
rs1476581546 334 dbSNP
rs774090925 335 dbSNP
rs761331446 336 dbSNP
rs369353752 341 dbSNP
rs1035403319 350 dbSNP
rs149702464 351 dbSNP
rs993115795 354 dbSNP
rs1456056960 356 dbSNP
rs999003249 360 dbSNP
rs915871240 361 dbSNP
rs895631699 362 dbSNP
rs948526292 363 dbSNP
rs773649559 369 dbSNP
rs1376752270 373 dbSNP
rs772325544 378 dbSNP
rs1012729896 381 dbSNP
rs1285380307 387 dbSNP
rs1209689246 395 dbSNP
rs925672417 396 dbSNP
rs1354471822 414 dbSNP
rs1022816116 420 dbSNP
rs952701240 421 dbSNP
rs1005467432 422 dbSNP
rs1276160524 425 dbSNP
rs373374707 429 dbSNP
rs1016010132 434 dbSNP
rs1327019279 440 dbSNP
rs1322609436 441 dbSNP
rs961436513 451 dbSNP
rs1396162830 461 dbSNP
rs780391521 468 dbSNP
rs1346986065 479 dbSNP
rs1464591490 479 dbSNP
rs922714638 483 dbSNP
rs954148334 484 dbSNP
rs1243241328 487 dbSNP
rs1052886616 488 dbSNP
rs1198538076 489 dbSNP
rs761264276 498 dbSNP
rs1467440761 500 dbSNP
rs1255045442 507 dbSNP
rs890082734 515 dbSNP
rs944390006 526 dbSNP
rs1270964006 527 dbSNP
rs746058048 539 dbSNP
rs1039257579 551 dbSNP
rs1339965605 555 dbSNP
rs900793450 587 dbSNP
rs946919711 589 dbSNP
rs1262659738 597 dbSNP
rs1042679330 598 dbSNP
rs14321 604 dbSNP
rs1192132925 615 dbSNP
rs1027755767 618 dbSNP
rs1330276119 621 dbSNP
rs530002580 627 dbSNP
rs1455037262 628 dbSNP
rs1176116985 632 dbSNP
rs886622625 633 dbSNP
rs1452898110 635 dbSNP
rs1397253651 637 dbSNP
rs1194725614 638 dbSNP
rs1056834947 651 dbSNP
rs1231438485 656 dbSNP
rs1206651557 663 dbSNP
rs548407997 672 dbSNP
rs1277751323 674 dbSNP
rs1232013637 680 dbSNP
rs1350039287 683 dbSNP
rs1385204141 688 dbSNP
rs1303873428 699 dbSNP
rs1239208106 703 dbSNP
rs1436845738 711 dbSNP
rs1323566139 712 dbSNP
rs1280959280 713 dbSNP
rs1035115881 717 dbSNP
rs768849621 735 dbSNP
rs1350045578 740 dbSNP
rs1370016692 760 dbSNP
rs990871329 763 dbSNP
rs1022873555 765 dbSNP
rs1377836204 766 dbSNP
rs1439491434 767 dbSNP
rs777063502 770 dbSNP
rs1063131 773 dbSNP
rs969985168 774 dbSNP
rs1179177806 780 dbSNP
rs978691283 783 dbSNP
rs754283272 785 dbSNP
rs1236966534 786 dbSNP
rs1046978 790 dbSNP
rs1208908791 794 dbSNP
rs1044210505 795 dbSNP
rs770327830 798 dbSNP
rs1215564889 808 dbSNP
rs773759508 811 dbSNP
rs1308620851 815 dbSNP
rs1223980306 817 dbSNP
rs1290865553 818 dbSNP
rs1378075897 818 dbSNP
rs1416136946 822 dbSNP
rs955906210 824 dbSNP
rs1314050411 825 dbSNP
rs1353045978 829 dbSNP
rs1343819295 831 dbSNP
rs569749749 833 dbSNP
rs1015542805 836 dbSNP
rs1212063350 843 dbSNP
rs530686755 851 dbSNP
rs897131227 853 dbSNP
rs1192870358 854 dbSNP
rs1272903691 857 dbSNP
rs1262265578 859 dbSNP
rs1216280929 862 dbSNP
rs998119298 864 dbSNP
rs1046980 870 dbSNP
rs1029632803 878 dbSNP
rs954095940 879 dbSNP
rs1334927077 880 dbSNP
rs1294384029 885 dbSNP
rs985512558 893 dbSNP
rs1046983 896 dbSNP
rs550016051 901 dbSNP
rs1360576448 903 dbSNP
rs571373906 915 dbSNP
rs538670762 916 dbSNP
rs1195952428 931 dbSNP
rs1022883658 933 dbSNP
rs968273804 934 dbSNP
rs1249024068 949 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ugcaaauuuaaaguGGGGAAGa 5'
                        ||||||| 
Target 5' --------------CCCCUUCu 3'
1 - 8
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000002829.3 | 3UTR | CCCCUUCUCCCCUCCCCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
Click to see details
133 hsa-miR-3179 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102087 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT110061 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112198 BTG2 BTG anti-proliferation factor 2 2 2
MIRT117668 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT146657 MINK1 misshapen like kinase 1 2 2
MIRT175505 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT180535 TXNIP thioredoxin interacting protein 2 2
MIRT190624 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT190650 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT366902 NONO non-POU domain containing octamer binding 2 2
MIRT443554 ZFP3 ZFP3 zinc finger protein 2 2
MIRT445953 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT446042 HMCN1 hemicentin 1 2 2
MIRT447968 MSH6 mutS homolog 6 2 2
MIRT448634 ONECUT1 one cut homeobox 1 2 2
MIRT449316 MRO maestro 2 2
MIRT451380 C19orf43 telomerase RNA component interacting RNase 2 2
MIRT451547 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451807 CDCA3 cell division cycle associated 3 2 4
MIRT451916 ILK integrin linked kinase 2 2
MIRT451938 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452189 KIAA1456 KIAA1456 2 2
MIRT452498 HMGXB3 HMG-box containing 3 2 2
MIRT452548 ZNF467 zinc finger protein 467 2 2
MIRT453844 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454515 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455363 KDM5C lysine demethylase 5C 2 2
MIRT455455 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455628 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 10
MIRT455639 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 10
MIRT455690 GLO1 glyoxalase I 2 2
MIRT456300 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT456784 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT456819 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457566 ZNF34 zinc finger protein 34 2 2
MIRT457604 IDS iduronate 2-sulfatase 2 2
MIRT458236 NXPH3 neurexophilin 3 2 2
MIRT458313 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458350 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458670 GPR35 G protein-coupled receptor 35 2 2
MIRT459675 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT461126 RAB36 RAB36, member RAS oncogene family 2 2
MIRT461918 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462301 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463520 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464378 URM1 ubiquitin related modifier 1 2 2
MIRT464614 UBE4B ubiquitination factor E4B 2 2
MIRT464711 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465520 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465974 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466058 TMEM189 transmembrane protein 189 2 2
MIRT466548 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT466647 TAGLN2 transgelin 2 2 2
MIRT467357 SP2 Sp2 transcription factor 2 2
MIRT468744 SDC2 syndecan 2 2 2
MIRT470244 PRRC2A proline rich coiled-coil 2A 2 2
MIRT471426 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT471732 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472190 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472450 NAV2 neuron navigator 2 2 6
MIRT474563 KLHDC3 kelch domain containing 3 2 2
MIRT474936 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475165 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475399 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT475426 ICK intestinal cell kinase 2 2
MIRT477090 FAM168A family with sequence similarity 168 member A 2 2
MIRT478458 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478953 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480096 CALR calreticulin 2 2
MIRT481924 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT483217 APOA1 apolipoprotein A1 2 6
MIRT483882 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483923 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483942 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484209 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484512 SYT7 synaptotagmin 7 2 2
MIRT484709 RNF11 ring finger protein 11 2 2
MIRT485356 MYO1C myosin IC 2 4
MIRT485615 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT486584 ZNF619 zinc finger protein 619 2 2
MIRT487013 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487621 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487801 GPR20 G protein-coupled receptor 20 2 4
MIRT488134 GPR107 G protein-coupled receptor 107 2 2
MIRT488773 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488854 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489783 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490102 FN3K fructosamine 3 kinase 2 2
MIRT490389 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT490434 MYL9 myosin light chain 9 2 2
MIRT490451 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490880 OSBP oxysterol binding protein 2 2
MIRT491037 ALPK3 alpha kinase 3 2 2
MIRT491250 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491748 SEMA3F semaphorin 3F 2 2
MIRT492235 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492490 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492505 RANBP10 RAN binding protein 10 2 4
MIRT492773 PDGFB platelet derived growth factor subunit B 2 2
MIRT492922 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT493459 ITFG3 family with sequence similarity 234 member A 2 2
MIRT493654 HDLBP high density lipoprotein binding protein 2 2
MIRT494011 DUSP9 dual specificity phosphatase 9 2 2
MIRT499412 PLCG2 phospholipase C gamma 2 2 4
MIRT499552 C15orf43 telomere repeat binding bouquet formation protein 2 2 2
MIRT501836 NCOA2 nuclear receptor coactivator 2 2 2
MIRT501950 MAT2A methionine adenosyltransferase 2A 2 10
MIRT504066 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT504509 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT508466 HOXB6 homeobox B6 2 4
MIRT512373 CPM carboxypeptidase M 2 2
MIRT513578 EVX1 even-skipped homeobox 1 2 2
MIRT517763 ZNF366 zinc finger protein 366 2 4
MIRT519773 ZNF354B zinc finger protein 354B 2 8
MIRT523568 GGCX gamma-glutamyl carboxylase 2 4
MIRT532802 CLDN11 claudin 11 2 2
MIRT544299 TSPYL1 TSPY like 1 2 2
MIRT544862 MYH2 myosin heavy chain 2 2 4
MIRT556731 KLHL15 kelch like family member 15 2 4
MIRT564347 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568924 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT569012 CXorf36 chromosome X open reading frame 36 2 2
MIRT569256 FAM129B family with sequence similarity 129 member B 2 2
MIRT569591 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT569779 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT570034 FAM228A family with sequence similarity 228 member A 2 2
MIRT573803 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574190 ZNF264 zinc finger protein 264 2 2
MIRT576153 Hmox1 heme oxygenase 1 2 2
MIRT611311 CA8 carbonic anhydrase 8 2 4
MIRT673429 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT674976 SH3BP2 SH3 domain binding protein 2 2 2
MIRT692712 MEAF6 MYST/Esa1 associated factor 6 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-3179 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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