miRTarBase - #MIRT491791


—
pre-miRNA Information
pre-miRNA hsa-mir-4280   
Genomic Coordinates chr5: 87114879 - 87114954
Description Homo sapiens miR-4280 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4280
Sequence 11| GAGUGUAGUUCUGAGCAGAGC |31
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1267452683 6 dbSNP
rs921418201 13 dbSNP
rs975577876 15 dbSNP
rs562687273 20 dbSNP
rs968639930 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF24   
Synonyms KOX17, RSG-A, ZNF191, ZSCAN3, Zfp191
Description zinc finger protein 24
Transcript NM_006965   
Expression
Putative miRNA Targets on ZNF24
3'UTR of ZNF24
(miRNA target sites are highlighted)		 
>ZNF24|NM_006965|3'UTR
   1 GAAATTGAAAAAAAAAAAAGAATCAGCACTCAGGTCTTTTTCTTCAGAAATGAAGACAAAATTTAAAATATGAAATGATG
  81 CAGAATAGTTTTTTCCCTATTGACTGTCAGAAAATCCACTGGGAAATGTAAAAATCTTCACTCACCATTATGATATTTAT
 161 CTTGAAAGAAATGGTGTCATACCTGCCTAGAAACTGAAATTTTAAACTTAATTCAGGTCTTAATGCCTAAATTTTCCATG
 241 TGATGTTTATAGTCTGTATTACTTCTCCAAATAATGAACTACCTGATTCATTGTCCCTTTCTTGAAAGTTTCTTTTTTAA
 321 GACAAATACATTATTTCTGCATTGATCATTGAAATGTTCTTTATATGGATACATTCCCTTATATATTAAAAGGCAACAGG
 401 AATTACAAAGTCTGAAAACCATTTTAAACCATCTTTTAAAAATTTACCCTTATTTCCTTTTACCTAATTTGAATATGCAT
 481 TTGAGAAAATAAGAGGATAAAGGATGGCTAAGAGCCTCAAAATGAACCATAAGATCTCAGATAAGAAGTGATGGTGATAA
 561 AACATCAAAAAGTGAATGGAACACCTTGATTGGGGAAGATATGCAAATACTTTGATCTAAGAATTGAAATGTATCAAGAA
 641 TTTATATTTTGCCTGCAGGAAAATTCAAAAGCTACTCATCCTCTCTATAATTTGGAGTCATCTTACTAATGAAAATAATG
 721 TTTTCCCATATATTATTAAAAAGCATACAGTCTAAATAATAAACAGTTGTAAAATAATGAAGGTAGAAATTATAACACTA
 801 GGGAAAAATTTGTAGCGGATGGCAGTGTTGAAGGCAAATGTAAACATAAGGGTAATGGTCTGTCATGGCTTTTAGAAAAA
 881 GATGATAGAGTTCATCATTATTTTGCCTTCATCTTTGTTAAGGACAGAAAATTCCCTGACAGGTGGGCAAGTATCAGGTT
 961 ACCTATTTTTTATTCCTTTGGTACAAAAGGGTTGAACGTCAGGCTAAAAAAGCAGCCATGCATTTATTATTAAACATTTT
1041 CTACCGACAAGGCACTGTGCTAGGTACTGTAATCCTACCATAAGTAGGTAGGTATTTCTTCCACTGTAAATCATAGGGGT
1121 TTGCTGTTTTATGTGAGTTAGCCTCTTCCCCTTGTCTGAGCATTCCTCAGGGGAGGTCACCTGTGAGGTTCCCAGAACTG
1201 TAGTTTTTTTTACCAGGGTGTTGTATTTGGAGGGGGAGGAGGACTCGGCTCAAAAGAGCTAGCTGGCTCTCCAGTGTTCA
1281 GAGGTGAGTCCACGATACTCTTACCACAATTTGGAAGTTTGTGAATCTTTTTAAAGAACTAATCAATCTCTAATAGCATT
1361 GAGGTTGTACCTACATATTAAGTTGAATGGACTGTTCTATTTAAAAAATAAACAACTAGACAATTAACTAGTTTATTAAC
1441 CTATCACAATTGAATTTTTTTTTAATTTTCAGTCTTAACACATTTTTTAAAATGTATTAAAGTAATACATTGTAGTAGTA
1521 GGATTATATACTCCTTGGCTGAGAATTCCAAGTACTGTGGTTCTACTGTTTAGTGGAAAACTCTGGAAGTTAAAATATAG
1601 AATATGAGAGGAGGCTTTTTTATAATGGGCATCATTGTGTGGAAAATGACCCATGTGAATACAAATATTTCCTAGTTCAG
1681 AGATTTTGGTTATATCTGGTGCTTGGATCAAGTTTAAAAATGGAAGGTGAGATTTTGCATGAGCCTATTAAAAAGCATAG
1761 TAATAAATGCAAGGCCAGCTGGTGGAAAAGTGAGGCAGAATGGAGCTTGTTTATAGGTTTTCTGATAACAATTATAAAAA
1841 ATGTGCTTTATAGATTAAGATTTATTGAAGTATAAATATGTAGTAATGATATAATGTATTTTAAGTTATACAAGAAAATG
1921 TAGGGACTTTTGTTTGGGTCTTTTTCTCTTTGTGGCTGAGGGGAAACAAGTCAGTGTCCAATAAAGCTGTAAACTCCTCT
2001 GCTCTAAGATAAATGATGTGATTTATTTATTTATAACTGGCTTCTTTCCAAGTAGGTTTTCAGGTGGCATATTTGGAAGA
2081 CGGCTGGAATGACAGAATTCTTGTATCAGAGTAGGTAAGAAGGGAGCAACCTCTCAATGGCTATTATGTCATGCTTTTTA
2161 AGATCGTATGCGGTTCCTATATACAAGGAAGCTTCCCTGTGGTAGATTTGTCATAAATGCCAAAGATATTTGGTAATGTG
2241 AGTGTAGAAAAAGTAGTATGAGGGTTGGCAAATACTGTTTTTGTCTTGGCAGCTCTAATATCTGCATTGTTCAGAAAGGA
2321 TTCTGAGGCTAAGGCAAAGCTCTGTGGGAAAAAGGGACTGGACCAAAAAAAACTGGATGGTGGCACACAAGAAGAGGAAA
2401 TGATGAGATGTGTACTTTCTATCTCTGGTTAGGCTTAGTCCCCACTAGACAAATTGATTTTAAATACTATGTAGTGATTT
2481 TTAAATTCCATCCACACATTCATTACCCACACAGATAATCATAGAAATTTGGGGGAGTGCCTAGCTTCTGATGAAGTGGT
2561 GATATGGCAGTGCCAAGCAGTGGCATCGCCAGAGTATCTGTTTGGTTAGCAAATGAGCAGTCATTTTAGGTCATGCAGAT
2641 TGCTGATATCTGCCCAGTAGCCACTGAGCATTTGCTGGTTTTTTCTTCTGGCTTTCTTGGAGGTTAAGCTCTCTGTAGTC
2721 ATACCCAGTTGGTACTTGATCTTTAGCAATATGTCTCATATTCATGTAAATTGAAGGGAGGGTTACATGTACTGAAATAA
2801 TCTGCATGCTAGGCATTGGCTTAGACACCGTACCTATCTCACTTAGATTTGTGGACTAGGAAAGCAAGATTCAGAGATCA
2881 TGTGACTTGCATGTGGCCTAGAGATAAAATTCAAATCTGGTTCTGTAGACTCCAGGGACATATTCACCATGCCATGGGTG
2961 GTGGCTATTAAACCTTGATAAATTTGTGTTTATGGTTAACAAATGTGAAAGCTATTAAACATTGCTGGTTTGAATTTTTT
3041 ACAGTGCAGAAATGTAAAATGAAAAAGGATATTTCCTTTCACAGTGTTACCGAGAAGTCATGATAATTTCGTTTGTTCTT
3121 CCAGATTTAGGCATATACTTATTTAATCAATAATGTGTTAACAGCTGACACCTGTGGTTGCTGTGACAGGCACTATTTGA
3201 AGTGCTTTATCATGGATTAACTCTTAATCCTCAGCTACCGTATAAAGTAGGACATAACCCCATTTCACATGCACTACACT
3281 GAGACTTGCCTCCTCTCCCCCCACATTGAAGATGTTCTTTTTTCATAACTATATACTATTCCATTGCATGAATATTCTGT
3361 AATTTATTTAATCCCCTATGGATTGATAATTAGGTTCATTATAGATAGAAGTGTAATTAACATTCCTGTACATGTATTTT
3441 GCTACTTGTGTGGGTATTTCTGTAGGATGAATAACTAGAAATTTATTGGATCAGGTTTCACATTTGCAGTTTTGAAAACT
3521 ACTACCAAAAAGATTTCACCAATTTACAACTCCATCATTAGTAAGAATGCCTGTTTGCCTATAGTCTGCCAACCCTGAAT
3601 CCTTAAAAATTTTTGCCAATCTGGTAGGCAAAATTTCTTTCTTTTCTTTGAATATTAATGAGGAGGAACATCTTTTCATG
3681 TTTCTTGGCCATTTGCATTTCCTATTATGAATTGCTTTTGCCCATTTTCCTTTTTTTAATTATGAAAGTCTAATGACTAC
3761 CTTCTCATTGTATAAAAAACACAGTTCTTTGAATAGAGAGACCCTTTTCTCCAATGCTACCAATCACATTCCACTTACCA
3841 CAGTTTAACATACATCCTCTAGTCACCTTTCCGTACGAATATACATACACATAAAAACACTTTTTACATAAATAGGATCT
3921 CATATTCTGTAGCTTTTTAAAATTTTGGTCTCAAAAAAAGATAACAGGTCTTTAAATTTCTTTAATGGTTGAATATGATT
4001 AAATACTATGAAAATGCCATTATTTATTCCCTTAATTTTTTTCCTCTCGCTATTACATTGCCAAAGTAAACATCCTATTC
4081 AGATGTCTTTGTGCATGTGTGTGAATATTTCTTTAGTCTGGAGTCCAGTAAGGTGGATTTTTGGATCAAAGGGTTTGTTC
4161 TCTGTCCACCTTCAGTCTTCCCAAAGGCCTTCATAACTGTATTTTCACCAAGTGTATGGAGAATGTTCATTTCCCCATAT
4241 AACCATACCTACACTTGATAGTTTTTATCTGTTGGGCGAAAAAGAACCTTTTCTTATTTTGCATTTCCCTGATTATAAAA
4321 AAAAATGGTGAGATTGGGGTTATTTTCATGTTTATTGGCCATTTATAGTTTACTGTGGATTGTTTGTATCCCTTACCTGC
4401 TTTCTATTGGGTTATGTGTGGATATATTGTTTTTATTTGTTCAGCATCTCCTTCCCCATCTTCTGGTAACACAACCTTTA
4481 TTTATTTGTGGGGAACCTATTCCCTGTGGCTTAGGTGAGCATGTGACCAGGCCTGGCCTCCTGAGTCCCACAGCTTCCTA
4561 GCCACAGTGATAAAAGAATGGGTATATAACTTAAGCCAGGCTAAGGAAAGCCCTTAACAGAACTTCTGCTGGAACTACTG
4641 GAAAGAAGGCTTTATGGAGATCCCAGGAACCAAGGACCATGTAAGCCTGAATTTGTGCCATGTGGAGAGAGTCTGTCTGA
4721 GGAGAAACTCGGATGCTAGCAGAAATGGAAAGAGAACTAAGTTCTGATGTCATTTTTCTGGAGGCCCTAGATCCAGCTGT
4801 GCCTAAAGCCTGCCCTACCTCCGGACTTTAAAGTTTTGTGAGCCAATAAAGTCCCTTTCTTGTTTAAGATAATTGAATTG
4881 AGTTTCTGTTCTGATTAATATAGGTTATTTGTATTTTCTTATTGATTTGTAGAAAACCTTTGTAATTTTAAATTCTAGAC
4961 TTTATGCACTATATAAGTTAATAAAATTAGCATGGCCTTCCATGATTTGGCCTGTGTCAACTTT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgaGACGAGU-CUUGAUGUGAg 5'
             :| | || | |||||||| 
Target 5' ccaTTTCACATGCACTACACTg 3'
 3260 - 3281 154.00 -9.80
2 
miRNA  3' cgagacgaGUCUUGAUGUGAg 5'
                  || | ||||||| 
Target 5' catataacCATACCTACACTt 3'
 4236 - 4256 149.00 -9.60
3 
miRNA  3' cgAGACGAGUCUUGAUGUGAg 5'
            ||  |||:  |:||||:| 
Target 5' ttTCCTCTCGCTATTACATTg 3'
 4040 - 4060 127.00 -11.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31783373 7 COSMIC
COSN32059119 7 COSMIC
COSN20042611 8 COSMIC
COSN30738292 17 COSMIC
COSN31575502 72 COSMIC
COSN18716153 89 COSMIC
COSN17272416 95 COSMIC
COSN9331857 164 COSMIC
COSN21052821 492 COSMIC
COSN28733002 977 COSMIC
COSN6120306 985 COSMIC
COSN28677273 1034 COSMIC
COSN21525440 1514 COSMIC
COSN1738731 1647 COSMIC
COSN19605624 1811 COSMIC
COSN27133839 2149 COSMIC
COSN6120305 2481 COSMIC
COSN20114905 2570 COSMIC
COSN17788487 2842 COSMIC
COSN26361500 3086 COSMIC
COSN25959109 3102 COSMIC
COSN21643357 3142 COSMIC
COSN4772438 3489 COSMIC
COSN25005869 3532 COSMIC
COSN25162131 3667 COSMIC
COSN27280672 3779 COSMIC
COSN8396171 4010 COSMIC
COSN17792511 4278 COSMIC
COSN31542893 4400 COSMIC
COSN24306443 4497 COSMIC
COSN1205270 4629 COSMIC
COSN31548944 4645 COSMIC
COSN24982358 4689 COSMIC
COSN1205269 4873 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1297741927 1 dbSNP
rs1440042860 6 dbSNP
rs778580357 7 dbSNP
rs1180052840 10 dbSNP
rs373840623 12 dbSNP
rs1424447396 14 dbSNP
rs753025544 15 dbSNP
rs1160818320 17 dbSNP
rs780673751 19 dbSNP
rs1064752 20 dbSNP
rs371928337 20 dbSNP
rs745811624 20 dbSNP
rs749438638 20 dbSNP
rs757149087 20 dbSNP
rs779989552 20 dbSNP
rs1305891556 22 dbSNP
rs751261950 22 dbSNP
rs756547539 23 dbSNP
rs757955278 23 dbSNP
rs777530494 23 dbSNP
rs372243052 24 dbSNP
rs1489151069 30 dbSNP
rs781540783 32 dbSNP
rs952771127 34 dbSNP
rs1221340125 39 dbSNP
rs1231845889 42 dbSNP
rs1256105753 45 dbSNP
rs754233503 46 dbSNP
rs570879880 50 dbSNP
rs1025695531 52 dbSNP
rs1019302272 57 dbSNP
rs759621702 70 dbSNP
rs895787036 72 dbSNP
rs1172143875 74 dbSNP
rs546190995 75 dbSNP
rs546858965 78 dbSNP
rs1035365295 81 dbSNP
rs1432853461 81 dbSNP
rs1176822426 85 dbSNP
rs1409655684 95 dbSNP
rs1003443129 96 dbSNP
rs371232278 99 dbSNP
rs936157411 113 dbSNP
rs904732638 123 dbSNP
rs34926675 124 dbSNP
rs773064011 127 dbSNP
rs529878248 133 dbSNP
rs1044866811 156 dbSNP
rs1351281305 165 dbSNP
rs769748353 172 dbSNP
rs1230674766 174 dbSNP
rs188417421 178 dbSNP
rs541997533 181 dbSNP
rs948811500 185 dbSNP
rs35943974 188 dbSNP
rs1385893266 197 dbSNP
rs1301282536 206 dbSNP
rs1485944868 233 dbSNP
rs917220083 238 dbSNP
rs1343558814 241 dbSNP
rs1207694709 245 dbSNP
rs893556853 248 dbSNP
rs1245368549 254 dbSNP
rs1208409037 260 dbSNP
rs1318976226 270 dbSNP
rs1488246064 281 dbSNP
rs796956654 285 dbSNP
rs1269824818 301 dbSNP
rs1426803630 305 dbSNP
rs1188065001 308 dbSNP
rs939903531 315 dbSNP
rs1430364763 318 dbSNP
rs1170191760 329 dbSNP
rs1223294150 330 dbSNP
rs1307665152 330 dbSNP
rs1052106485 332 dbSNP
rs1295192510 338 dbSNP
rs1415994649 342 dbSNP
rs1375344401 345 dbSNP
rs935018730 347 dbSNP
rs1369356744 349 dbSNP
rs908462781 350 dbSNP
rs1296282720 356 dbSNP
rs1366498215 360 dbSNP
rs1231276463 365 dbSNP
rs922275842 368 dbSNP
rs1288085556 375 dbSNP
rs977438228 376 dbSNP
rs1455627122 379 dbSNP
rs1222850569 382 dbSNP
rs1346614371 388 dbSNP
rs576085272 396 dbSNP
rs767019674 400 dbSNP
rs1463746929 407 dbSNP
rs867010593 414 dbSNP
rs562544300 446 dbSNP
rs372546191 447 dbSNP
rs911420508 450 dbSNP
rs1411622102 451 dbSNP
rs1423013700 452 dbSNP
rs1165275439 456 dbSNP
rs984291355 460 dbSNP
rs140858508 464 dbSNP
rs1475511583 479 dbSNP
rs761790405 481 dbSNP
rs183034447 484 dbSNP
rs1388739784 492 dbSNP
rs1436732499 503 dbSNP
rs1208479191 507 dbSNP
rs1028144901 509 dbSNP
rs972787887 511 dbSNP
rs1261086162 527 dbSNP
rs528132936 529 dbSNP
rs554201759 532 dbSNP
rs1327275437 533 dbSNP
rs1208355632 534 dbSNP
rs776262337 545 dbSNP
rs1019671587 552 dbSNP
rs534483165 562 dbSNP
rs1003901759 563 dbSNP
rs190448885 570 dbSNP
rs1482908610 590 dbSNP
rs1315331129 593 dbSNP
rs1419778289 596 dbSNP
rs765317356 596 dbSNP
rs1412330597 602 dbSNP
rs2974909 602 dbSNP
rs1010700440 607 dbSNP
rs1031921703 613 dbSNP
rs779770351 617 dbSNP
rs904678772 622 dbSNP
rs1449432836 626 dbSNP
rs1355410390 629 dbSNP
rs1349020102 630 dbSNP
rs1228233918 641 dbSNP
rs73428514 644 dbSNP
rs1384281233 646 dbSNP
rs145766357 647 dbSNP
rs187589105 654 dbSNP
rs549236811 657 dbSNP
rs530991660 676 dbSNP
rs908575352 677 dbSNP
rs911486527 682 dbSNP
rs1181250397 683 dbSNP
rs563941262 684 dbSNP
rs984343430 684 dbSNP
rs1470979436 685 dbSNP
rs369677711 687 dbSNP
rs931486768 687 dbSNP
rs1417080598 690 dbSNP
rs1369304880 706 dbSNP
rs1185409996 717 dbSNP
rs918740729 718 dbSNP
rs1309059124 720 dbSNP
rs1352518545 732 dbSNP
rs975232270 733 dbSNP
rs972841594 735 dbSNP
rs1274263468 738 dbSNP
rs960141441 738 dbSNP
rs1221073947 739 dbSNP
rs1185685677 740 dbSNP
rs1463739719 744 dbSNP
rs1255069269 745 dbSNP
rs1204132517 747 dbSNP
rs928663706 750 dbSNP
rs529990654 752 dbSNP
rs1275122287 760 dbSNP
rs1214414470 761 dbSNP
rs1196307332 764 dbSNP
rs1245833039 766 dbSNP
rs560931896 781 dbSNP
rs1271346395 782 dbSNP
rs1230320240 786 dbSNP
rs779511645 793 dbSNP
rs1169566516 800 dbSNP
rs1399087625 802 dbSNP
rs1308566549 803 dbSNP
rs1323128865 804 dbSNP
rs1331950931 809 dbSNP
rs1443160798 810 dbSNP
rs1295539881 816 dbSNP
rs373112352 817 dbSNP
rs1380837326 823 dbSNP
rs2974910 827 dbSNP
rs545342399 838 dbSNP
rs1207899962 840 dbSNP
rs531712418 842 dbSNP
rs1451861609 850 dbSNP
rs1804714 851 dbSNP
rs1393167527 853 dbSNP
rs1160933210 854 dbSNP
rs1463502317 858 dbSNP
rs183264464 860 dbSNP
rs1375346379 865 dbSNP
rs957897526 870 dbSNP
rs1030787005 876 dbSNP
rs1169516373 884 dbSNP
rs1411774495 884 dbSNP
rs1447377018 886 dbSNP
rs1255131717 888 dbSNP
rs999721780 890 dbSNP
rs900923522 891 dbSNP
rs1463234525 894 dbSNP
rs1318562998 899 dbSNP
rs369361735 899 dbSNP
rs1296188232 903 dbSNP
rs1242296499 917 dbSNP
rs1328177823 917 dbSNP
rs1283410992 922 dbSNP
rs1265407333 926 dbSNP
rs1234761392 927 dbSNP
rs1265928389 929 dbSNP
rs752800364 930 dbSNP
rs895848479 934 dbSNP
rs1251186042 946 dbSNP
rs545875296 958 dbSNP
rs1369427500 962 dbSNP
rs1006572595 963 dbSNP
rs1350580990 964 dbSNP
rs1304603816 965 dbSNP
rs889430325 970 dbSNP
rs7239712 977 dbSNP
rs560530218 989 dbSNP
rs1048403958 990 dbSNP
rs1321050320 993 dbSNP
rs1392578984 995 dbSNP
rs751619224 997 dbSNP
rs191173763 998 dbSNP
rs541448808 1003 dbSNP
rs921191400 1004 dbSNP
rs1297470887 1016 dbSNP
rs1286047199 1018 dbSNP
rs931539819 1030 dbSNP
rs1328099442 1033 dbSNP
rs1064753 1034 dbSNP
rs1396720937 1044 dbSNP
rs1037196733 1045 dbSNP
rs530926397 1046 dbSNP
rs983652513 1049 dbSNP
rs185943141 1056 dbSNP
rs1200392338 1058 dbSNP
rs1257572433 1073 dbSNP
rs1486848266 1079 dbSNP
rs1180527576 1080 dbSNP
rs928742180 1082 dbSNP
rs980563322 1083 dbSNP
rs1473058021 1087 dbSNP
rs1161316774 1091 dbSNP
rs1376010643 1096 dbSNP
rs1464423246 1101 dbSNP
rs1376082204 1103 dbSNP
rs987896027 1106 dbSNP
rs1436322122 1110 dbSNP
rs544784768 1112 dbSNP
rs924916831 1114 dbSNP
rs1391629874 1118 dbSNP
rs979104104 1119 dbSNP
rs767245072 1121 dbSNP
rs140616144 1123 dbSNP
rs558716049 1125 dbSNP
rs989392438 1132 dbSNP
rs1281637360 1138 dbSNP
rs1350728551 1141 dbSNP
rs377259469 1142 dbSNP
rs1274397180 1143 dbSNP
rs1486925738 1151 dbSNP
rs1481048071 1152 dbSNP
rs1179173500 1156 dbSNP
rs1023225262 1160 dbSNP
rs1281547593 1164 dbSNP
rs1432647313 1171 dbSNP
rs1013623765 1179 dbSNP
rs957948411 1188 dbSNP
rs1030836834 1190 dbSNP
rs1436531029 1192 dbSNP
rs1166423083 1197 dbSNP
rs1369727063 1198 dbSNP
rs1036296696 1202 dbSNP
rs1462368961 1202 dbSNP
rs1388189250 1207 dbSNP
rs1385698852 1211 dbSNP
rs1303542056 1212 dbSNP
rs559577679 1212 dbSNP
rs1297237041 1213 dbSNP
rs887206082 1223 dbSNP
rs151335329 1224 dbSNP
rs999375053 1225 dbSNP
rs555873658 1230 dbSNP
rs965559072 1233 dbSNP
rs1214349077 1235 dbSNP
rs1455483892 1246 dbSNP
rs1019377431 1247 dbSNP
rs1007032380 1253 dbSNP
rs889484197 1257 dbSNP
rs1048082589 1261 dbSNP
rs1428868265 1267 dbSNP
rs1272660429 1269 dbSNP
rs12455822 1273 dbSNP
rs1335905003 1279 dbSNP
rs552891691 1280 dbSNP
rs1039589335 1284 dbSNP
rs1305657241 1288 dbSNP
rs575308484 1293 dbSNP
rs142446324 1294 dbSNP
rs1363321155 1298 dbSNP
rs1216651897 1299 dbSNP
rs1311059355 1304 dbSNP
rs1313285750 1304 dbSNP
rs557137874 1313 dbSNP
rs1044516166 1323 dbSNP
rs948800463 1332 dbSNP
rs576594233 1333 dbSNP
rs1160579912 1337 dbSNP
rs914616756 1344 dbSNP
rs1470625306 1345 dbSNP
rs990112534 1349 dbSNP
rs1486169612 1350 dbSNP
rs1187992704 1364 dbSNP
rs934628491 1367 dbSNP
rs1474637155 1373 dbSNP
rs777809642 1377 dbSNP
rs923894020 1378 dbSNP
rs758533213 1387 dbSNP
rs567521965 1398 dbSNP
rs1476493703 1399 dbSNP
rs1258773980 1413 dbSNP
rs760525245 1415 dbSNP
rs575927126 1416 dbSNP
rs991740045 1416 dbSNP
rs1228713181 1428 dbSNP
rs144515017 1436 dbSNP
rs1415840624 1442 dbSNP
rs1019851871 1445 dbSNP
rs1350917733 1447 dbSNP
rs1266974592 1448 dbSNP
rs1285076360 1463 dbSNP
rs960589894 1464 dbSNP
rs983365194 1464 dbSNP
rs1485215024 1470 dbSNP
rs985261448 1470 dbSNP
rs1471418214 1471 dbSNP
rs1176067579 1475 dbSNP
rs951429389 1477 dbSNP
rs774969130 1479 dbSNP
rs181053346 1481 dbSNP
rs953773939 1482 dbSNP
rs1026693633 1488 dbSNP
rs1338540625 1493 dbSNP
rs1320013708 1502 dbSNP
rs995177450 1506 dbSNP
rs1348808585 1507 dbSNP
rs1409462051 1508 dbSNP
rs577525442 1510 dbSNP
rs1375618087 1521 dbSNP
rs896794405 1522 dbSNP
rs1015863584 1537 dbSNP
rs190814211 1540 dbSNP
rs1217603283 1554 dbSNP
rs530652451 1557 dbSNP
rs1384481621 1559 dbSNP
rs907404436 1560 dbSNP
rs1282214572 1563 dbSNP
rs1008123915 1565 dbSNP
rs376411458 1566 dbSNP
rs2974911 1571 dbSNP
rs560290922 1573 dbSNP
rs1054440661 1578 dbSNP
rs1455105475 1579 dbSNP
rs1175860959 1596 dbSNP
rs934681548 1598 dbSNP
rs1194310053 1611 dbSNP
rs1409821200 1611 dbSNP
rs924589299 1622 dbSNP
rs1434358367 1631 dbSNP
rs1274358977 1637 dbSNP
rs1286294520 1638 dbSNP
rs1447243358 1649 dbSNP
rs1234935262 1650 dbSNP
rs745562278 1653 dbSNP
rs947812800 1655 dbSNP
rs978061927 1656 dbSNP
rs943945058 1658 dbSNP
rs1195057640 1664 dbSNP
rs148729796 1671 dbSNP
rs1439222083 1675 dbSNP
rs912436778 1678 dbSNP
rs985292001 1682 dbSNP
rs953822452 1692 dbSNP
rs1251854345 1693 dbSNP
rs992251458 1705 dbSNP
rs1026747349 1711 dbSNP
rs866833258 1712 dbSNP
rs1336392455 1720 dbSNP
rs530344120 1727 dbSNP
rs938915033 1737 dbSNP
rs973793701 1739 dbSNP
rs561976887 1747 dbSNP
rs1475279745 1750 dbSNP
rs961062724 1756 dbSNP
rs1015669346 1758 dbSNP
rs1421867464 1772 dbSNP
rs1003168312 1775 dbSNP
rs1403825838 1778 dbSNP
rs28438034 1798 dbSNP
rs112286532 1803 dbSNP
rs575959097 1808 dbSNP
rs534313990 1809 dbSNP
rs893283727 1812 dbSNP
rs1327810550 1820 dbSNP
rs1027138976 1824 dbSNP
rs1431138489 1828 dbSNP
rs1054495145 1831 dbSNP
rs1270578482 1833 dbSNP
rs1340971951 1838 dbSNP
rs964116355 1841 dbSNP
rs1018247397 1843 dbSNP
rs1008651855 1849 dbSNP
rs1215076106 1851 dbSNP
rs1318712811 1861 dbSNP
rs891004241 1875 dbSNP
rs1395388248 1876 dbSNP
rs1031333503 1879 dbSNP
rs1446963369 1879 dbSNP
rs186303978 1880 dbSNP
rs764181950 1883 dbSNP
rs934732126 1883 dbSNP
rs1418908140 1886 dbSNP
rs572845428 1888 dbSNP
rs1043601098 1889 dbSNP
rs1040773509 1890 dbSNP
rs1382627593 1891 dbSNP
rs944684533 1891 dbSNP
rs1168866621 1892 dbSNP
rs947760642 1895 dbSNP
rs1412769993 1896 dbSNP
rs1475251322 1896 dbSNP
rs912475186 1899 dbSNP
rs1388700256 1909 dbSNP
rs1292272920 1916 dbSNP
rs1335122495 1920 dbSNP
rs1234547518 1922 dbSNP
rs1049642763 1925 dbSNP
rs1186342365 1931 dbSNP
rs1469514284 1936 dbSNP
rs1370054887 1939 dbSNP
rs1350503368 1940 dbSNP
rs1253123791 1943 dbSNP
rs1287025360 1948 dbSNP
rs1220130956 1950 dbSNP
rs1187725159 1952 dbSNP
rs1449819303 1963 dbSNP
rs932489694 1965 dbSNP
rs1180037223 1968 dbSNP
rs749745755 1979 dbSNP
rs973854392 1981 dbSNP
rs1056097148 1984 dbSNP
rs561010631 1991 dbSNP
rs1387112042 1996 dbSNP
rs1295114157 2000 dbSNP
rs1312085039 2001 dbSNP
rs369273227 2001 dbSNP
rs961417960 2004 dbSNP
rs939013780 2006 dbSNP
rs1416248024 2008 dbSNP
rs1304503474 2015 dbSNP
rs1334645527 2020 dbSNP
rs76035223 2020 dbSNP
rs1047751957 2023 dbSNP
rs145460873 2024 dbSNP
rs181261808 2025 dbSNP
rs762923626 2025 dbSNP
rs1434323072 2035 dbSNP
rs981524809 2046 dbSNP
rs971058948 2051 dbSNP
rs1330223658 2064 dbSNP
rs1203282103 2074 dbSNP
rs1429657008 2080 dbSNP
rs1023192009 2081 dbSNP
rs974226207 2082 dbSNP
rs964063211 2100 dbSNP
rs756365865 2103 dbSNP
rs1172720873 2110 dbSNP
rs1375833202 2122 dbSNP
rs1436418568 2127 dbSNP
rs957564375 2129 dbSNP
rs567136169 2130 dbSNP
rs1391422587 2131 dbSNP
rs986943503 2144 dbSNP
rs1369346510 2146 dbSNP
rs1304900173 2147 dbSNP
rs556864181 2147 dbSNP
rs536943110 2154 dbSNP
rs999422975 2165 dbSNP
rs1250940843 2166 dbSNP
rs903269100 2171 dbSNP
rs1205207477 2172 dbSNP
rs1482675997 2179 dbSNP
rs1265378672 2180 dbSNP
rs1468144479 2183 dbSNP
rs571119191 2185 dbSNP
rs1212703471 2186 dbSNP
rs1455395356 2190 dbSNP
rs1168093629 2195 dbSNP
rs1372091824 2199 dbSNP
rs1462187574 2202 dbSNP
rs1348883680 2205 dbSNP
rs879905544 2206 dbSNP
rs1022106367 2211 dbSNP
rs1300765365 2218 dbSNP
rs1217684720 2219 dbSNP
rs1040423267 2225 dbSNP
rs1009324235 2229 dbSNP
rs889097285 2245 dbSNP
rs1327141155 2254 dbSNP
rs1373883655 2256 dbSNP
rs1375692072 2259 dbSNP
rs139929512 2264 dbSNP
rs1308240571 2268 dbSNP
rs895019412 2276 dbSNP
rs1056611201 2284 dbSNP
rs932550141 2290 dbSNP
rs919798922 2293 dbSNP
rs1214440536 2295 dbSNP
rs1253501233 2297 dbSNP
rs1038215184 2305 dbSNP
rs939839306 2306 dbSNP
rs538778572 2309 dbSNP
rs1435667960 2311 dbSNP
rs1260779405 2324 dbSNP
rs1359388911 2330 dbSNP
rs1428973120 2333 dbSNP
rs566922886 2345 dbSNP
rs535249651 2347 dbSNP
rs1047403781 2354 dbSNP
rs1435878775 2358 dbSNP
rs930201324 2365 dbSNP
rs1397267288 2366 dbSNP
rs908302001 2371 dbSNP
rs1409588360 2373 dbSNP
rs1011939623 2386 dbSNP
rs1363076265 2390 dbSNP
rs1038461280 2397 dbSNP
rs1249469661 2399 dbSNP
rs1291634859 2419 dbSNP
rs1355096188 2421 dbSNP
rs1233920069 2425 dbSNP
rs756825311 2426 dbSNP
rs1275139113 2428 dbSNP
rs942867871 2440 dbSNP
rs911428979 2451 dbSNP
rs971495594 2455 dbSNP
rs1260136906 2468 dbSNP
rs73428511 2469 dbSNP
rs763695573 2470 dbSNP
rs762488724 2471 dbSNP
rs1195631781 2472 dbSNP
rs1254914594 2479 dbSNP
rs1474689562 2488 dbSNP
rs1187977121 2495 dbSNP
rs1255182324 2499 dbSNP
rs1398519029 2504 dbSNP
rs548789956 2511 dbSNP
rs561266993 2512 dbSNP
rs1318921164 2516 dbSNP
rs1455633617 2517 dbSNP
rs1311465056 2518 dbSNP
rs374718209 2519 dbSNP
rs1375009751 2524 dbSNP
rs957615029 2533 dbSNP
rs923912097 2534 dbSNP
rs1295417836 2540 dbSNP
rs1371263700 2543 dbSNP
rs748574752 2544 dbSNP
rs1223342884 2559 dbSNP
rs1285081418 2562 dbSNP
rs551338910 2562 dbSNP
rs1227805884 2564 dbSNP
rs374963025 2565 dbSNP
rs565478782 2567 dbSNP
rs200937126 2571 dbSNP
rs397743638 2571 dbSNP
rs200373541 2572 dbSNP
rs3833196 2572 dbSNP
rs202083661 2573 dbSNP
rs959457847 2586 dbSNP
rs545552999 2587 dbSNP
rs1378980627 2588 dbSNP
rs1003680882 2589 dbSNP
rs9958086 2592 dbSNP
rs994463254 2596 dbSNP
rs368238536 2600 dbSNP
rs1441522244 2603 dbSNP
rs1298845565 2604 dbSNP
rs1346558397 2605 dbSNP
rs1159288498 2606 dbSNP
rs1242232082 2620 dbSNP
rs1456186946 2620 dbSNP
rs1409122908 2622 dbSNP
rs1346866840 2630 dbSNP
rs1167087009 2631 dbSNP
rs755162654 2633 dbSNP
rs1424303225 2638 dbSNP
rs1435739628 2641 dbSNP
rs1203135910 2646 dbSNP
rs16966670 2649 dbSNP
rs1179857976 2655 dbSNP
rs1486983399 2656 dbSNP
rs1192291972 2658 dbSNP
rs1242855136 2663 dbSNP
rs139135062 2666 dbSNP
rs1458278217 2678 dbSNP
rs1050415961 2684 dbSNP
rs771379021 2685 dbSNP
rs994802073 2685 dbSNP
rs556529802 2688 dbSNP
rs188796892 2691 dbSNP
rs1409624776 2703 dbSNP
rs1038267421 2705 dbSNP
rs113254844 2709 dbSNP
rs886928832 2711 dbSNP
rs1323771300 2713 dbSNP
rs1327247761 2715 dbSNP
rs1045919453 2718 dbSNP
rs577488010 2724 dbSNP
rs942994888 2734 dbSNP
rs949822905 2742 dbSNP
rs1051288303 2744 dbSNP
rs150809967 2754 dbSNP
rs924029069 2769 dbSNP
rs978212034 2781 dbSNP
rs991117690 2782 dbSNP
rs1252878204 2784 dbSNP
rs1201392366 2787 dbSNP
rs1216644258 2787 dbSNP
rs534853535 2792 dbSNP
rs1240725808 2797 dbSNP
rs565716974 2817 dbSNP
rs1411655536 2824 dbSNP
rs766433241 2830 dbSNP
rs1433885950 2836 dbSNP
rs1459903522 2838 dbSNP
rs1164328190 2842 dbSNP
rs1393567592 2845 dbSNP
rs977676132 2851 dbSNP
rs1324451084 2859 dbSNP
rs1385867087 2863 dbSNP
rs758490230 2867 dbSNP
rs1342027004 2870 dbSNP
rs990719718 2878 dbSNP
rs185990099 2879 dbSNP
rs988002016 2881 dbSNP
rs764126029 2893 dbSNP
rs1446764849 2901 dbSNP
rs953446306 2905 dbSNP
rs1367768321 2911 dbSNP
rs760340578 2914 dbSNP
rs1474356727 2916 dbSNP
rs1187226309 2919 dbSNP
rs1430015407 2925 dbSNP
rs115128701 2928 dbSNP
rs1026016203 2931 dbSNP
rs181802526 2933 dbSNP
rs1399859321 2939 dbSNP
rs1298608036 2942 dbSNP
rs1017289241 2943 dbSNP
rs1004121494 2949 dbSNP
rs113701195 2954 dbSNP
rs1340538185 2957 dbSNP
rs1246412407 2960 dbSNP
rs1007528015 2961 dbSNP
rs1278265623 2963 dbSNP
rs1350615054 2966 dbSNP
rs1206029456 2977 dbSNP
rs1045564917 2992 dbSNP
rs775331051 2995 dbSNP
rs867569963 3004 dbSNP
rs1258542047 3025 dbSNP
rs902718978 3034 dbSNP
rs1179790424 3041 dbSNP
rs1361947562 3041 dbSNP
rs1488454414 3051 dbSNP
rs1055440969 3054 dbSNP
rs1381936289 3069 dbSNP
rs116865748 3075 dbSNP
rs1311877007 3079 dbSNP
rs1230252772 3080 dbSNP
rs531251954 3082 dbSNP
rs1308504865 3084 dbSNP
rs553422714 3091 dbSNP
rs978104942 3092 dbSNP
rs1241501864 3101 dbSNP
rs551771065 3102 dbSNP
rs1362525760 3104 dbSNP
rs1305012970 3105 dbSNP
rs190834800 3110 dbSNP
rs912092232 3111 dbSNP
rs369689211 3115 dbSNP
rs927907192 3124 dbSNP
rs987666819 3132 dbSNP
rs953499593 3133 dbSNP
rs1029103357 3135 dbSNP
rs982476377 3141 dbSNP
rs1179165939 3142 dbSNP
rs570123099 3142 dbSNP
rs1239999136 3148 dbSNP
rs1370995911 3155 dbSNP
rs1452307868 3156 dbSNP
rs1172816027 3165 dbSNP
rs184322023 3166 dbSNP
rs1026133830 3174 dbSNP
rs973108109 3189 dbSNP
rs1395126296 3190 dbSNP
rs1014919616 3192 dbSNP
rs1333912586 3209 dbSNP
rs963114142 3213 dbSNP
rs1440562582 3217 dbSNP
rs1199693500 3225 dbSNP
rs375208123 3227 dbSNP
rs1432599347 3235 dbSNP
rs559687764 3238 dbSNP
rs369456326 3239 dbSNP
rs573356094 3240 dbSNP
rs1259870379 3242 dbSNP
rs889994776 3244 dbSNP
rs55689466 3245 dbSNP
rs1267785342 3248 dbSNP
rs1203391871 3250 dbSNP
rs1434747103 3250 dbSNP
rs773550048 3253 dbSNP
rs542981038 3260 dbSNP
rs1172217899 3284 dbSNP
rs560080525 3288 dbSNP
rs1461385415 3294 dbSNP
rs999887490 3295 dbSNP
rs1339646283 3297 dbSNP
rs1294701902 3299 dbSNP
rs1257323003 3301 dbSNP
rs904220082 3302 dbSNP
rs893903219 3303 dbSNP
rs772283066 3312 dbSNP
rs770354441 3324 dbSNP
rs1271353013 3325 dbSNP
rs1055496559 3331 dbSNP
rs938024705 3335 dbSNP
rs577204473 3341 dbSNP
rs945670978 3345 dbSNP
rs1203192590 3351 dbSNP
rs116880958 3354 dbSNP
rs1477949768 3357 dbSNP
rs1195131503 3358 dbSNP
rs1307205788 3369 dbSNP
rs1474630106 3371 dbSNP
rs1046297892 3373 dbSNP
rs919068777 3375 dbSNP
rs781533335 3376 dbSNP
rs1288680541 3377 dbSNP
rs1427520745 3380 dbSNP
rs1361333359 3388 dbSNP
rs1402073092 3394 dbSNP
rs1291726184 3398 dbSNP
rs534611776 3401 dbSNP
rs1228999392 3406 dbSNP
rs572248771 3407 dbSNP
rs1377507580 3408 dbSNP
rs1052425510 3432 dbSNP
rs1323451253 3434 dbSNP
rs1050189 3448 dbSNP
rs536751656 3450 dbSNP
rs1285052767 3454 dbSNP
rs922082643 3456 dbSNP
rs1465711082 3462 dbSNP
rs368321488 3462 dbSNP
rs1376035416 3464 dbSNP
rs910303131 3469 dbSNP
rs973520883 3478 dbSNP
rs1181973372 3485 dbSNP
rs1416530159 3486 dbSNP
rs1417870273 3490 dbSNP
rs1473215290 3492 dbSNP
rs1158640531 3499 dbSNP
rs1381296237 3500 dbSNP
rs963455872 3502 dbSNP
rs557405740 3507 dbSNP
rs778981908 3509 dbSNP
rs1448788124 3512 dbSNP
rs537474390 3517 dbSNP
rs1381169564 3519 dbSNP
rs983477732 3521 dbSNP
rs571645501 3523 dbSNP
rs1200728380 3524 dbSNP
rs1242109100 3526 dbSNP
rs1277705948 3532 dbSNP
rs1000654799 3540 dbSNP
rs971105150 3542 dbSNP
rs548598972 3554 dbSNP
rs1479403529 3561 dbSNP
rs1024242257 3574 dbSNP
rs1014107385 3581 dbSNP
rs552096772 3586 dbSNP
rs1178542584 3590 dbSNP
rs796574058 3593 dbSNP
rs114184985 3602 dbSNP
rs1172187128 3607 dbSNP
rs1424652852 3609 dbSNP
rs566271298 3610 dbSNP
rs966967514 3611 dbSNP
rs999940046 3613 dbSNP
rs904281281 3619 dbSNP
rs1011082773 3621 dbSNP
rs1330555537 3624 dbSNP
rs894018807 3626 dbSNP
rs11545098 3628 dbSNP
rs1041831113 3633 dbSNP
rs1301001148 3634 dbSNP
rs1366388104 3638 dbSNP
rs1219432871 3647 dbSNP
rs868542014 3649 dbSNP
rs549283926 3650 dbSNP
rs528970953 3654 dbSNP
rs1305221447 3665 dbSNP
rs867955998 3669 dbSNP
rs1197489964 3701 dbSNP
rs563079401 3707 dbSNP
rs1459490689 3718 dbSNP
rs1052048608 3721 dbSNP
rs1400275295 3723 dbSNP
rs1192068060 3733 dbSNP
rs1246482944 3738 dbSNP
rs1046850531 3740 dbSNP
rs1160381216 3741 dbSNP
rs543093181 3743 dbSNP
rs532812711 3745 dbSNP
rs919181731 3750 dbSNP
rs1037877405 3754 dbSNP
rs1171508594 3755 dbSNP
rs1037456397 3756 dbSNP
rs563917818 3757 dbSNP
rs1321570211 3758 dbSNP
rs907964111 3761 dbSNP
rs1330273827 3763 dbSNP
rs983915893 3772 dbSNP
rs1276206985 3774 dbSNP
rs1359458424 3782 dbSNP
rs1217424230 3784 dbSNP
rs1278281235 3786 dbSNP
rs970774554 3793 dbSNP
rs910407165 3799 dbSNP
rs78471288 3801 dbSNP
rs1452520047 3802 dbSNP
rs1464426772 3802 dbSNP
rs559813519 3802 dbSNP
rs922935658 3805 dbSNP
rs1240530093 3811 dbSNP
rs192569268 3814 dbSNP
rs1238457431 3829 dbSNP
rs555556580 3831 dbSNP
rs1021215990 3838 dbSNP
rs1034196776 3838 dbSNP
rs1011198765 3842 dbSNP
rs1161357169 3843 dbSNP
rs1441509244 3843 dbSNP
rs1405686051 3854 dbSNP
rs999999099 3856 dbSNP
rs1325294214 3859 dbSNP
rs1358160242 3861 dbSNP
rs376225404 3862 dbSNP
rs1399003340 3869 dbSNP
rs968934011 3872 dbSNP
rs1210062458 3876 dbSNP
rs1230969462 3877 dbSNP
rs1284083714 3879 dbSNP
rs1357701994 3881 dbSNP
rs148195345 3882 dbSNP
rs1266912317 3885 dbSNP
rs543520980 3886 dbSNP
rs1488208067 3888 dbSNP
rs542088519 3891 dbSNP
rs537537674 3900 dbSNP
rs1030002201 3903 dbSNP
rs571709306 3905 dbSNP
rs576481264 3908 dbSNP
rs557825953 3912 dbSNP
rs993460528 3913 dbSNP
rs1338929104 3936 dbSNP
rs1362101055 3944 dbSNP
rs535349712 3950 dbSNP
rs1393742299 3954 dbSNP
rs1037572891 3960 dbSNP
rs1307792256 3960 dbSNP
rs1450814579 3960 dbSNP
rs532176969 3960 dbSNP
rs1037927839 3964 dbSNP
rs941977121 3968 dbSNP
rs566208725 3982 dbSNP
rs1346006121 3983 dbSNP
rs1436067870 3987 dbSNP
rs888933682 3999 dbSNP
rs1444254129 4006 dbSNP
rs1050701426 4009 dbSNP
rs549638101 4016 dbSNP
rs933053779 4017 dbSNP
rs1318589802 4029 dbSNP
rs923016263 4034 dbSNP
rs1171705379 4035 dbSNP
rs1402282454 4046 dbSNP
rs942228223 4048 dbSNP
rs1376836330 4049 dbSNP
rs886585860 4049 dbSNP
rs1311921530 4058 dbSNP
rs1047837095 4067 dbSNP
rs1232789091 4077 dbSNP
rs945687567 4081 dbSNP
rs1163057060 4087 dbSNP
rs1471976984 4093 dbSNP
rs949491013 4096 dbSNP
rs1256023808 4098 dbSNP
rs917955442 4109 dbSNP
rs1457273706 4114 dbSNP
rs990782374 4115 dbSNP
rs937986138 4121 dbSNP
rs902219258 4124 dbSNP
rs927232443 4128 dbSNP
rs1431288519 4133 dbSNP
rs1375137957 4134 dbSNP
rs573067593 4152 dbSNP
rs189192501 4159 dbSNP
rs1205369928 4168 dbSNP
rs958548698 4171 dbSNP
rs549507798 4172 dbSNP
rs988619031 4173 dbSNP
rs1206226153 4195 dbSNP
rs1453269728 4201 dbSNP
rs1033821310 4209 dbSNP
rs981355448 4219 dbSNP
rs755399981 4227 dbSNP
rs954619389 4228 dbSNP
rs970797582 4239 dbSNP
rs1025011930 4242 dbSNP
rs758372318 4245 dbSNP
rs12969499 4247 dbSNP
rs993575312 4248 dbSNP
rs1030053164 4250 dbSNP
rs1354062711 4252 dbSNP
rs532826199 4254 dbSNP
rs900144258 4256 dbSNP
rs564114027 4258 dbSNP
rs1006066712 4267 dbSNP
rs1253060716 4267 dbSNP
rs1209044186 4272 dbSNP
rs184057984 4275 dbSNP
rs889038993 4277 dbSNP
rs1016547419 4278 dbSNP
rs1050232384 4287 dbSNP
rs1006868966 4296 dbSNP
rs901711868 4297 dbSNP
rs191838608 4298 dbSNP
rs750541858 4307 dbSNP
rs1323559866 4308 dbSNP
rs1048358890 4312 dbSNP
rs1294502646 4317 dbSNP
rs1041477040 4326 dbSNP
rs1393065114 4326 dbSNP
rs949539095 4340 dbSNP
rs144175580 4342 dbSNP
rs1220591016 4351 dbSNP
rs896589097 4354 dbSNP
rs1169575129 4359 dbSNP
rs1449721450 4365 dbSNP
rs1055111650 4371 dbSNP
rs1389108600 4372 dbSNP
rs371695853 4373 dbSNP
rs74919042 4382 dbSNP
rs945800803 4404 dbSNP
rs938037221 4406 dbSNP
rs1246767062 4418 dbSNP
rs1198134916 4446 dbSNP
rs1213978805 4464 dbSNP
rs925274478 4465 dbSNP
rs1449765886 4466 dbSNP
rs187468497 4470 dbSNP
rs1254621680 4472 dbSNP
rs544792610 4473 dbSNP
rs1205551200 4488 dbSNP
rs947291246 4497 dbSNP
rs1272669137 4499 dbSNP
rs1221152014 4506 dbSNP
rs1368472356 4525 dbSNP
rs1158243613 4530 dbSNP
rs1274313795 4533 dbSNP
rs1434984251 4534 dbSNP
rs1361432130 4539 dbSNP
rs1352814156 4540 dbSNP
rs577461574 4547 dbSNP
rs989059963 4549 dbSNP
rs1301166914 4577 dbSNP
rs1429438476 4579 dbSNP
rs542121808 4582 dbSNP
rs954538322 4587 dbSNP
rs1030102254 4595 dbSNP
rs367823310 4597 dbSNP
rs756044111 4601 dbSNP
rs1167949408 4613 dbSNP
rs576350760 4618 dbSNP
rs1415795988 4621 dbSNP
rs1361291760 4626 dbSNP
rs971294642 4627 dbSNP
rs1284807470 4632 dbSNP
rs1353989916 4634 dbSNP
rs556383267 4654 dbSNP
rs1190085487 4655 dbSNP
rs752640611 4660 dbSNP
rs964400444 4668 dbSNP
rs1182929484 4674 dbSNP
rs1015929788 4679 dbSNP
rs1245558250 4698 dbSNP
rs1253817910 4702 dbSNP
rs1438182399 4704 dbSNP
rs749840526 4717 dbSNP
rs1178421694 4721 dbSNP
rs1381075686 4728 dbSNP
rs1006512307 4730 dbSNP
rs1174289086 4731 dbSNP
rs1358627831 4732 dbSNP
rs951036092 4736 dbSNP
rs183134800 4739 dbSNP
rs972100188 4751 dbSNP
rs1212576508 4754 dbSNP
rs1050232 4764 dbSNP
rs1050236 4778 dbSNP
rs962116340 4779 dbSNP
rs1444236555 4797 dbSNP
rs1026532073 4809 dbSNP
rs1217485512 4813 dbSNP
rs1331840803 4822 dbSNP
rs1377454101 4823 dbSNP
rs1289599162 4829 dbSNP
rs1014190115 4832 dbSNP
rs1311075537 4833 dbSNP
rs193082939 4847 dbSNP
rs896641359 4850 dbSNP
rs1265494804 4864 dbSNP
rs1055166917 4865 dbSNP
rs3207959 4868 dbSNP
rs1006636764 4869 dbSNP
rs1304926455 4877 dbSNP
rs1050256 4891 dbSNP
rs1449821246 4898 dbSNP
rs1002236590 4900 dbSNP
rs903905575 4901 dbSNP
rs1359330527 4911 dbSNP
rs1471388387 4913 dbSNP
rs1050258 4918 dbSNP
rs577999213 4922 dbSNP
rs1467714128 4928 dbSNP
rs1424761804 4942 dbSNP
rs1050266 4955 dbSNP
rs1050270 4968 dbSNP
rs1433795177 4970 dbSNP
rs1044121129 4971 dbSNP
rs552828212 4973 dbSNP
rs534743893 4986 dbSNP
rs1463997329 4989 dbSNP
rs572384053 4990 dbSNP
rs1400736005 4991 dbSNP
rs997473266 4993 dbSNP
rs1053016473 4996 dbSNP
rs1272680685 5001 dbSNP
rs1183328496 5005 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgaGACGAGU-CUUGAUGUGAg 5'
             :| | || | |||||||| 
Target 5' ccaUUUCACAUGCACUACACUg 3'
 		9 - 30
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000589881.1 | 3UTR | ACAUAACCCCAUUUCACAUGCACUACACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
67 hsa-miR-4280 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT065612 DAZAP2 DAZ associated protein 2 2 10
MIRT084985 BACH1 BTB domain and CNC homolog 1 2 2
MIRT088053 UBXN2A UBX domain protein 2A 2 4
MIRT097327 SCAMP1 secretory carrier membrane protein 1 2 2
MIRT099148 MYLIP myosin regulatory light chain interacting protein 2 12
MIRT127042 FAM208B family with sequence similarity 208 member B 2 4
MIRT140479 BNIP2 BCL2 interacting protein 2 2 6
MIRT154889 GNAS GNAS complex locus 2 4
MIRT187983 MBD6 methyl-CpG binding domain protein 6 2 2
MIRT190440 EIF5 eukaryotic translation initiation factor 5 2 2
MIRT240673 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT295049 EVI5L ecotropic viral integration site 5 like 2 2
MIRT324749 ACER2 alkaline ceramidase 2 2 2
MIRT366075 FAM127A retrotransposon Gag like 8C 2 4
MIRT442625 LOX lysyl oxidase 2 2
MIRT445224 TYRP1 tyrosinase related protein 1 2 2
MIRT448967 CCNT2 cyclin T2 2 4
MIRT450137 PFN4 profilin family member 4 2 2
MIRT464350 USP46 ubiquitin specific peptidase 46 2 2
MIRT470460 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT473691 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT480188 CALM2 calmodulin 2 2 6
MIRT486355 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT486708 TROVE2 TROVE domain family member 2 2 4
MIRT488337 SCD stearoyl-CoA desaturase 2 2
MIRT489322 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT491791 ZNF24 zinc finger protein 24 2 2
MIRT491970 USP37 ubiquitin specific peptidase 37 2 2
MIRT492029 TWF1 twinfilin actin binding protein 1 2 4
MIRT492063 TMEM245 transmembrane protein 245 2 2
MIRT492247 SLC39A9 solute carrier family 39 member 9 2 2
MIRT492254 SLC35F5 solute carrier family 35 member F5 2 2
MIRT492592 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493436 KAT7 lysine acetyltransferase 7 2 2
MIRT493470 IPMK inositol polyphosphate multikinase 2 2
MIRT493639 HECTD1 HECT domain E3 ubiquitin protein ligase 1 2 2
MIRT493919 FAM127B retrotransposon Gag like 8A 2 4
MIRT494639 ARNTL aryl hydrocarbon receptor nuclear translocator like 2 2
MIRT500032 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT504589 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2 4
MIRT505535 SP4 Sp4 transcription factor 2 6
MIRT507539 DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 2 6
MIRT508846 TMCO1 transmembrane and coiled-coil domains 1 2 4
MIRT510488 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT511402 IFNAR2 interferon alpha and beta receptor subunit 2 2 6
MIRT523252 HIST1H2AH histone cluster 1 H2A family member h 2 2
MIRT525939 C11orf74 chromosome 11 open reading frame 74 2 2
MIRT531453 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT533317 UNKL unkempt family like zinc finger 2 2
MIRT541034 STRBP spermatid perinuclear RNA binding protein 2 8
MIRT546734 RNF217 ring finger protein 217 2 2
MIRT555125 PTPRJ protein tyrosine phosphatase, receptor type J 2 2
MIRT556105 MOAP1 modulator of apoptosis 1 2 2
MIRT560205 AK4 adenylate kinase 4 2 2
MIRT561087 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT566967 LBR lamin B receptor 2 2
MIRT567344 H3F3B H3 histone family member 3B 2 2
MIRT567863 DCAF12 DDB1 and CUL4 associated factor 12 2 2
MIRT574449 SCML2 Scm polycomb group protein like 2 2 2
MIRT575700 Map1b microtubule-associated protein 1B 2 2
MIRT651432 YIPF6 Yip1 domain family member 6 2 2
MIRT659728 CCDC93 coiled-coil domain containing 93 2 2
MIRT686937 SFT2D3 SFT2 domain containing 3 2 2
MIRT699385 SLC30A6 solute carrier family 30 member 6 2 2
MIRT710287 CSNK1G3 casein kinase 1 gamma 3 2 2
MIRT715123 PANK3 pantothenate kinase 3 2 2
MIRT721847 VLDLR very low density lipoprotein receptor 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4280 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4280 Platinum 23939 resistant tissue
hsa-miR-4280 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4280 Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4280 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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