miRTarBase - #MIRT492058


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pre-miRNA Information
pre-miRNA hsa-mir-584   
Genomic Coordinates chr5: 149062313 - 149062409
Synonyms MIRN584, hsa-mir-584, MIR584
Description Homo sapiens miR-584 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-584-3p
Sequence 55| UCAGUUCCAGGCCAACCAGGCU |76
Evidence Not_experimental
Experiments
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30106292 7 COSMIC
COSN30491768 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1284744048 4 dbSNP
rs752976926 7 dbSNP
rs372036186 8 dbSNP
rs759702288 9 dbSNP
rs774701780 11 dbSNP
rs766864122 15 dbSNP
rs1268595998 16 dbSNP
rs763403123 17 dbSNP
rs746051876 18 dbSNP
rs536559251 20 dbSNP
rs761542149 21 dbSNP
Putative Targets

Gene Information
Gene Symbol TMEM59   
Synonyms C1orf8, DCF1, HSPC001, PRO195, UNQ169
Description transmembrane protein 59
Transcript NM_004872   
Expression
Putative miRNA Targets on TMEM59
3'UTR of TMEM59
(miRNA target sites are highlighted)		 
>TMEM59|NM_004872|3'UTR
   1 GCATTTTTCTTTTAAAAGACAAGTGTAATAGACATCTAAAATTCCACTCCTCATAGAGCTTTTAAAATGGTTTCATTGGA
  81 TATAGGCCTTAAGAAATCACTATAAAATGCAAATAAAGTTACTCAAATCTGTGAAGACTGTATTTGCTATAACTTTATTG
 161 GTATTGTTTTTGTAGTAATTTAAGAGGTGGATGTTTGGGATTGTATTATTATTTTACTAATATCTGTAGCTATTTTGTTT
 241 TTTGCTTTGGTTATTGTTTTTTTCCCTTTTCTTAGCTATGAGCTGATCATTGCTCCTTCTCACCTCCTGCCATGATACTG
 321 TCAGTTACCTTAGTTAACAAGCTGAATATTTAGTAGAAATGATGCTTCTGCTCAGGAATGGCCCACAAATCTGTAATTTG
 401 AAATTTAGCAGGAAATGACCTTTAATGACACTACATTTTCAGGAACTGAAATCATTAAAATTTTATTTGAATAATTATGT
 481 GCTGAAATTTGAGTATCTGATTTTTCTAGACCTTCCCTCCTATTCCTGCCCAACCTAGATAAGAATTATGAAATGTTCTG
 561 TGTTTATTGCTATTGCTTTATAATGTGATGGTCAGGGACCATTTTGATGCAAAACTGATCTCTCAGCAGTACATTTGATG
 641 TTATTTTGCACAGGCTATAGGTTTTTGTTTGATGAGTGTTTCCAAAGAACTATTTTTCTCTGTTAGATAGCATATCAAGT
 721 ATAAGGTAAACATATTTTCAGAGAAAACTTCATTTTAACACTAAAAATTAGACTCTTGTGATACAGAATTAAGTATAAAT
 801 TTTACTTGGCAAAAACTCGTTTTATTTTTACCTGCAATAATACAGAGCTTAATATTAGAATGATATCAGGTCATAATAAT
 881 AATACACCAGAATCTTTTGAGATGGAATTTTGCTCTTGTTGCTGAGGCTGGAGTGCAATGGTATGATCTTGGCTCACTAC
 961 AACCTCCACCTCTGAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCACAC
1041 CTGGATAATTTTGTATTTTTAGTAGAGACGGGGTTTCACCAGGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGA
1121 TCCACCCACTTAGGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGTGACTGTGCCCAGCCTACACCAGAATTCTAATATG
1201 ATTCACTGTTATTATGCCATAAAATATTAAAAACTTTGTAAAACAATACTTTCCTCAGTCACAGGGGCATTGCTGACAAC
1281 TGCATCAGTGCTGTTTGACTAAAGAATAAGTTAGTCACTCCTCCTATGGCCTAGTCTTTAGCCTTCCTGAGTCCAAATGA
1361 AAAGCAGTTAACAGCTAATCAAGGAAGACTTTGGTCACAAAGTGTAGGTTTTTATTTTTAGTTTGTCTAGATTTGGATGA
1441 TAGAAAGTTGTGAACACATCCAGATGGGGAAGAAAGGAGGAATTAGCCGTCATTGTCAAGCAGTCATTGTTTCTTTCTTC
1521 TTTTTGTTAGAAAACATGGGATAAAACGTGGGGACTCAGCCAGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGG
1601 AGGCCAAAGCAGGAGGATCACTTGAGGTCAGGAGTTCGAGACCAACCTGGGCAACATAGCAAGACCCTCTCTGTACAAAA
1681 AAATACAAACAAACATGGGGACTATATAAAACATGGGTAGTGGATAGGAGTTACCATTAAAAAAAAATAAAAAGCCCTGT
1761 TGTTTCGTCTCCCATCATTAGTGCATACTTAGTTTCCTTAGTCAGGCACAGGTTTAATTGTAATGCATCCAATGAAGCAA
1841 ACAGAGAAACACAAAATGCTGCTGTCTCACAGGAATCAAAGAGCCCACTGTTAGAAAAGACCCTCCCTTATAAAAACAAA
1921 ACAAAGAATTATCTAGATCACTTGGGGCCAGGAGTTCAACACCATCCTGGGCAATATAATGAGAATCCCATCTTTTTTTT
2001 TTTTTTTAAAGCAACTGTACAGTTGTCCTATATTCTCCACCTTCCCTTGGTTTCATTTCTCTTCGCTTCCTGAATGAGAA
2081 GTGCCTGAGATACCTTCATTTCTCTTGAAAGTATTGATCCAAGTTTAGACAAATATCTCCCCTCTTGTTGAGAGAATTCC
2161 TTATATGTGAAAATACCAAGACATTCTTGATATTTAGCAGGCACTCAAATATTTGTCTCCTCTTTTTTAGCATAATTAAG
2241 CCAGACTGATGTTTGCATTTGAGTATCATCAGCATGAGTAACCATTTTAATCTCTCTTCCCTTAACTACTTGTTCTACAC
2321 TAGAGTCTAGGGTCAGGGTACGTACAGTGATAAAGATTGAGATAATGGGAAATATAGTCTTCTGTTTGGGAAGCTGGATT
2401 GTAGTGTTGATTTTCTGACTCCTTGTGGTAATTAAATTCTGAAGCACAGAATCTACTTTTGAGAAGAAATATTTTACTTT
2481 TGAAAAAAAATCCCCAAAATATATACAGCATAAAAATGTTTCCGATCTTGAAAATCCCAACCAAAGCAACAAAACTGAGC
2561 TTCCAAGCCCCTTCTCCTAAAGTAACAGTTTTGCCCTTCTTGGATGTGCCTAACTTTACTTAGCTCCTTGTTTCCATAAA
2641 ACAGTCATAATCTTATTTCCTACCACACAGAAAGCATCTTGAGAATCTGGTCTTGGTCCTAGGCAAATTCTCAAGACCGT
2721 TGGGTCTCTGGTTCAAACCTCCCAGACTTCTAAGGTCTTTCTTGGCTCAGGTCCCTCATCTAAGAGACATGCTAATTCAG
2801 GCAATTACAAAAGCAGTACTAATCACCATAATGAATGATCTGGGCCTAGGTTCCAAGTTTTCTCACAAAACTTCATGGGC
2881 ACCTTTCATTTGTGATATGTTTTGTAGTAAATCAGAAATTACTAGATGATCTGGTCAATCTTATCTCAGAAATCCCTGTG
2961 GTGCATCATGAGGCAATCTGAGCTGCTGATCAGCAGAAAACCCTGCACTGTCTGAGCTTATCTTCCAGCCAAAGGCAAAC
3041 AATTTACCCTTTGTTATTAGTCTGTCTGGATTTGTCTTAGATAAATGAGCCATTTTTGTTACAAGTTTTTTAAAGATATA
3121 CAGTAGTTCCATTATAATTTTTGTGGACTCAAATATCAAGTCCACATGTAGGGAATCATTGACAGAGATTTCCAGTTACT
3201 GTCACCACCACACCAAGGCAGTAATTTTGCTCAGTTCTGCCTTTATAGATCCACAATTTAACCATTCAACAACCACCTGA
3281 GATCCTGAGTGGCAGGCCCTATGCTAAATGCTAGGACCACAGTAAGACCCAGTGCCTGACCCCAATTGCTGAGACTCTGA
3361 AGGAGACTATTATTAATGTGATAAGTGCTATGACCAAGCACAGAGCACATAGGAGGAGCTGTATGCATTATGGGAGCACA
3441 CAGGAGGACTTCTGGGAGAAAGTGATAGCCAAGCTTAAACCTGGAGAAAAAGGGAACGCCAAACACAATATAGAGAGCAG
3521 TGTACCAGACAGTGGGGACACTGTGCTCAAAGACCTAGAGGCCAGAGGGTGAGGCACTGCAGATTGTTGAGTAGGCCGAG
3601 ATAGAGCATACAAAAGCATAACAAAAGATGGGGCTAGGCAGACCAGGTAATAAACCTGCACTTTAAACCTGCACTTGATC
3681 CTGAGCACAGTAGAGAGCCACTGAAAGATTTTAAGCAAGAGAGTGCCATACAGTGTTGGAATGATTCACTCGGACAGCAA
3761 TGTGGAAGATAGACCAGAAAGGGCAAGTCCAGAGGCCAACAATAATCTTAGCCTCAGAGTTCTTTTTTTAATACCCAAGA
3841 ATACTATTTCATTTTACTTATATTTTTAAACTTTTCTCTATAACGCTCTCTCTGCTCCCCCACATTGTTGTCTGGATGGT
3921 AAACCTAGGACTGGTCTCTGAGTCCTGGTCACAGCCTGGCAACAGAATGTTTGAGCAAACTGGGAAGGCTGCCCCATGGA
4001 TCCCTGGTTTCTTATCACCATCCTCTTAATTCTACGTTTGCCAACCAGTCTCTAGGAAGCCAGCGTGCTCTTGCGCCCCT
4081 CCCACCAGGTTTCCAGTTGCTAAGCGTGTCATGTTTGCATTTGGGTATCATCTGCATGAGTGACCATTTTAATCTCTCTT
4161 TCCTTGACTACTTGTTCTACACTAGAGTCTAGGGTGGGGGTGAGTACAGTGGTAAAGACAGGGATAGCGGGAAATTTAGT
4241 CTTCTGTTTAGGAAGCTGGATGGTAGTGTGGATTTTCTAACTCCTTGTGGTAATTAAATTCTGGAGCACAGTTTTTAGAC
4321 CTTTTCTGAAATCTGTTACTGTTGAAGTCAGCTTCATATATTTCACTTTTTTTTTTTTTGAGACAGAGTCTCACACTGTT
4401 ACTCAGGCTGGAGTGCACTGGTACAATCTTGACTCACTGCAACCTCCACAGCTCCCAGGTTCAAGCGATTCTCGTGCCTC
4481 AGCCTCCCAAGTAGCTGGTACTACAGGCGCGTGCCACCATGCTTGGCTAATTTTTGTATTTCTAGTAAAGATGGGGTTTT
4561 GCCATGTTGCCCAGGCTGGTCTCGAACTCCTGGCCTCAGGTAATCTGCCCGCCTCAGCCTCCCAAAGTGTTTGGATTGCA
4641 GGCATGAGCCACTGCACCCACCCTATTTCACTATTAAGTACTCTCTTCCTGTGATATTAATGACTTATTTGTTTCAAACT
4721 TTTTTGTGCCATTGAGCTTTTTAGTGATCCAGTGAAGCCTGTGGACCCCCTCTCATAGTAATGTTTTCAAAGCATAAAAC
4801 TAAATATAAAGGATCGCAAAGGAAACTGATCATGTTAAAATAAAGTTGATATTTTCAAAGTTTTATGATCCAGTAACATA
4881 CATATTCTGTTAACACAAAATAAGACTGCATGGTGGTTCTAAAATTACTATAATTCAAATTCATATCTTGAAATATCTAA
4961 CAACTGTAATATATCTAAATGTCTCATTTCTATTGGTGACAAAGTCACAGGTACTCTGATCCTACTGTGGACTGTTTCCT
5041 ATATTCGTAATTGAAGGAAATGTTATATTTCAGTTAGAAGTTGGTGAAAAGAAAGATTTAAAATTTTTCCCATCCAAGTT
5121 CACCAGACCCCTGGTTTAGAGGTTGTCTTAATTTTACTTTTGTCATTTTAAGAGTAAATTATTTTGTTTTCTTGTTCAAT
5201 TCTCAATTATTTGGGCTTATTTTACTGCCTCTTGCATGCTTTTTTATGCTTGAATGGTTTTTGCAGTGTTAGAACAGTAA
5281 TAATTGAAGACTTGGGTGGAAAAAAATCAGCACCTGATTGAAAATGAAAGGTTTCAACAAAAGCTCTTGATAATGTTACC
5361 TCCAGGTGTACCATCATGCCACCATTATTGGTGCTACAAATCTGTTAATTTATTTATGCTTAAGTATGTAAACTTTAATA
5441 AAACTTGGATCATCTGCATTAAAAAATAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucggaccaaccGGACCUUGACu 5'
                     :| ||||||| 
Target 5' acactacatttTCAGGAACTGa 3'
 428 - 449 143.00 -14.10
2 
miRNA  3' ucggACCAACCGGACCUUGACu 5'
              ||| | |::|||:|:|| 
Target 5' gaggTGGAT-GTTTGGGATTGt 3'
 184 - 204 129.00 -15.90
3 
miRNA  3' ucGGACCAACCGGACCUUGAcu 5'
            || || |||:|| |||||  
Target 5' ggCCAGGCTGGTCTCGAACTcc 3'
 1086 - 1107 128.00 -19.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
587698 23 ClinVar
COSN28846873 4 COSMIC
COSN31606296 42 COSMIC
COSN30183437 56 COSMIC
COSN30107088 69 COSMIC
COSN31483112 426 COSMIC
COSN18935237 742 COSMIC
COSN24138882 743 COSMIC
COSN28217093 794 COSMIC
COSN21866618 837 COSMIC
COSN19030526 877 COSMIC
COSN16915886 1479 COSMIC
COSN29633820 1738 COSMIC
COSN8141785 1838 COSMIC
COSN1449192 1872 COSMIC
COSN29960688 1945 COSMIC
COSN27232501 1993 COSMIC
COSN22309901 2292 COSMIC
COSN8141784 2364 COSMIC
COSN20588332 2375 COSMIC
COSN21929930 2427 COSMIC
COSN21370110 2646 COSMIC
COSN29838269 2783 COSMIC
COSN21899786 3119 COSMIC
COSN6460006 3121 COSMIC
COSN6460005 3319 COSMIC
COSN16683526 4607 COSMIC
COSN23431430 4816 COSMIC
COSN16329824 4861 COSMIC
COSN32081686 4876 COSMIC
COSN14843955 5272 COSMIC
COSN6460004 5277 COSMIC
COSN8913377 5387 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs772939523 2 dbSNP
rs1249810497 3 dbSNP
rs3211030 9 dbSNP
rs769067645 12 dbSNP
rs749607121 18 dbSNP
rs1187881107 19 dbSNP
rs776119905 23 dbSNP
rs770182440 25 dbSNP
rs71765470 28 dbSNP
rs745991278 29 dbSNP
rs566378222 31 dbSNP
rs757281621 33 dbSNP
rs1802246 35 dbSNP
rs11539455 36 dbSNP
rs777793591 40 dbSNP
rs1161878228 44 dbSNP
rs370808647 45 dbSNP
rs3203929 46 dbSNP
rs752422115 50 dbSNP
rs1389987767 61 dbSNP
rs746777136 97 dbSNP
rs1044831 99 dbSNP
rs1316880911 106 dbSNP
rs1052882756 112 dbSNP
rs935746828 119 dbSNP
rs983348541 124 dbSNP
rs1326766518 136 dbSNP
rs767652255 137 dbSNP
rs1353870626 140 dbSNP
rs929139103 148 dbSNP
rs904247406 149 dbSNP
rs183023114 153 dbSNP
rs12504 160 dbSNP
rs1432740766 172 dbSNP
rs560815550 185 dbSNP
rs1187719532 205 dbSNP
rs948187724 209 dbSNP
rs1474050171 215 dbSNP
rs1363125628 216 dbSNP
rs1319972045 217 dbSNP
rs981678168 220 dbSNP
rs141637937 223 dbSNP
rs376352704 228 dbSNP
rs1023660363 230 dbSNP
rs113635438 237 dbSNP
rs530478295 240 dbSNP
rs990790882 254 dbSNP
rs1171237028 264 dbSNP
rs1415102812 270 dbSNP
rs1465885601 272 dbSNP
rs1333635575 282 dbSNP
rs958010769 283 dbSNP
rs1033010519 294 dbSNP
rs1171053890 299 dbSNP
rs1350825079 300 dbSNP
rs918574557 301 dbSNP
rs564718070 303 dbSNP
rs1183656336 312 dbSNP
rs114816695 316 dbSNP
rs748231688 317 dbSNP
rs1253679338 318 dbSNP
rs1199476288 319 dbSNP
rs998075780 344 dbSNP
rs900281935 346 dbSNP
rs1206775269 347 dbSNP
rs1252104374 352 dbSNP
rs985344693 353 dbSNP
rs765268683 361 dbSNP
rs11539454 375 dbSNP
rs954010028 380 dbSNP
rs1029602675 386 dbSNP
rs572829212 396 dbSNP
rs1478669901 406 dbSNP
rs1172540334 428 dbSNP
rs1226173426 430 dbSNP
rs1038778932 435 dbSNP
rs1393279038 446 dbSNP
rs1431724145 452 dbSNP
rs1308854531 476 dbSNP
rs998496205 493 dbSNP
rs1370261280 496 dbSNP
rs560700798 515 dbSNP
rs891686610 525 dbSNP
rs1332634587 526 dbSNP
rs1233832495 531 dbSNP
rs1297018137 537 dbSNP
rs1031358384 539 dbSNP
rs999826180 543 dbSNP
rs1230044828 555 dbSNP
rs1274901769 560 dbSNP
rs776976531 570 dbSNP
rs1480127797 572 dbSNP
rs1448815191 580 dbSNP
rs1342306228 584 dbSNP
rs1332469794 594 dbSNP
rs904283527 601 dbSNP
rs1395613912 618 dbSNP
rs1452558342 653 dbSNP
rs1198711308 657 dbSNP
rs571405470 661 dbSNP
rs887407582 670 dbSNP
rs1047840175 671 dbSNP
rs1170876028 675 dbSNP
rs948287450 677 dbSNP
rs1428447569 678 dbSNP
rs1547277 687 dbSNP
rs929277471 692 dbSNP
rs1164729424 693 dbSNP
rs1486723233 698 dbSNP
rs1056747285 700 dbSNP
rs778914420 701 dbSNP
rs1392530445 705 dbSNP
rs1473505723 709 dbSNP
rs1387149181 710 dbSNP
rs928522824 719 dbSNP
rs551729975 720 dbSNP
rs147916006 730 dbSNP
rs1436602434 731 dbSNP
rs939618834 752 dbSNP
rs1224707807 767 dbSNP
rs575231389 773 dbSNP
rs1366141651 776 dbSNP
rs1213536164 778 dbSNP
rs1357485440 778 dbSNP
rs1186405744 780 dbSNP
rs1466677810 781 dbSNP
rs948525156 782 dbSNP
rs1547467 783 dbSNP
rs1202728635 785 dbSNP
rs1189807265 800 dbSNP
rs972716291 804 dbSNP
rs941357027 810 dbSNP
rs910006587 818 dbSNP
rs145212116 819 dbSNP
rs958040580 837 dbSNP
rs1032379555 843 dbSNP
rs922439056 845 dbSNP
rs1360596994 847 dbSNP
rs1229916130 854 dbSNP
rs978496162 857 dbSNP
rs1314430374 866 dbSNP
rs1340741054 874 dbSNP
rs1233033593 885 dbSNP
rs1358582851 888 dbSNP
rs976556667 904 dbSNP
rs756557475 913 dbSNP
rs967011091 932 dbSNP
rs1260664454 938 dbSNP
rs1484925848 939 dbSNP
rs1310292724 941 dbSNP
rs59566166 943 dbSNP
rs1475029324 947 dbSNP
rs750693240 955 dbSNP
rs1415339313 957 dbSNP
rs997698595 962 dbSNP
rs1159800201 969 dbSNP
rs1370285479 973 dbSNP
rs1324796232 974 dbSNP
rs1344609714 977 dbSNP
rs1450961071 980 dbSNP
rs900632051 984 dbSNP
rs1017373607 985 dbSNP
rs999898887 994 dbSNP
rs1472740601 998 dbSNP
rs558680657 1002 dbSNP
rs1006008275 1006 dbSNP
rs1229457550 1007 dbSNP
rs139703732 1011 dbSNP
rs1319423947 1014 dbSNP
rs1047412667 1021 dbSNP
rs1256610219 1025 dbSNP
rs369833702 1030 dbSNP
rs373031493 1031 dbSNP
rs1269266688 1032 dbSNP
rs1022738490 1034 dbSNP
rs907128484 1042 dbSNP
rs1223684807 1045 dbSNP
rs1417184211 1057 dbSNP
rs566612251 1069 dbSNP
rs1287890718 1070 dbSNP
rs948560638 1073 dbSNP
rs1329887900 1074 dbSNP
rs915712907 1082 dbSNP
rs1410789300 1087 dbSNP
rs773205782 1089 dbSNP
rs1003627909 1091 dbSNP
rs1226737727 1093 dbSNP
rs150776380 1101 dbSNP
rs925342817 1108 dbSNP
rs1347230282 1113 dbSNP
rs978146857 1117 dbSNP
rs1277005020 1120 dbSNP
rs1343206133 1123 dbSNP
rs1037242077 1125 dbSNP
rs1232053379 1134 dbSNP
rs967085658 1145 dbSNP
rs752282412 1156 dbSNP
rs1275804481 1160 dbSNP
rs941387898 1161 dbSNP
rs536012659 1169 dbSNP
rs1192795080 1171 dbSNP
rs1253606293 1173 dbSNP
rs1329829593 1175 dbSNP
rs1322346092 1177 dbSNP
rs769912980 1177 dbSNP
rs1453260165 1182 dbSNP
rs375238089 1189 dbSNP
rs1457344118 1198 dbSNP
rs142206441 1211 dbSNP
rs746977048 1214 dbSNP
rs976297112 1215 dbSNP
rs964950054 1240 dbSNP
rs550810978 1246 dbSNP
rs1439124043 1253 dbSNP
rs1425693529 1264 dbSNP
rs1370962034 1266 dbSNP
rs1006374626 1282 dbSNP
rs188444314 1283 dbSNP
rs1299860545 1288 dbSNP
rs776413676 1289 dbSNP
rs148691924 1297 dbSNP
rs976592510 1297 dbSNP
rs759242570 1308 dbSNP
rs78179002 1310 dbSNP
rs1193748914 1315 dbSNP
rs1223576404 1319 dbSNP
rs1465410479 1323 dbSNP
rs76546325 1325 dbSNP
rs1270020767 1334 dbSNP
rs143849834 1342 dbSNP
rs7526578 1343 dbSNP
rs1191692533 1347 dbSNP
rs1249301612 1352 dbSNP
rs1475458048 1356 dbSNP
rs978658578 1363 dbSNP
rs1045634554 1368 dbSNP
rs1023067020 1370 dbSNP
rs1166165447 1380 dbSNP
rs1012821429 1402 dbSNP
rs530274374 1403 dbSNP
rs1274804503 1406 dbSNP
rs894395715 1429 dbSNP
rs533301939 1434 dbSNP
rs544938570 1445 dbSNP
rs1430179184 1450 dbSNP
rs1366749856 1457 dbSNP
rs1268630580 1459 dbSNP
rs1003705060 1464 dbSNP
rs745620033 1465 dbSNP
rs897311141 1467 dbSNP
rs1293624551 1475 dbSNP
rs66521714 1479 dbSNP
rs149467829 1488 dbSNP
rs1293511864 1489 dbSNP
rs1042842779 1495 dbSNP
rs888679999 1505 dbSNP
rs1447077304 1508 dbSNP
rs1050191444 1513 dbSNP
rs1424134565 1520 dbSNP
rs932632829 1529 dbSNP
rs1188259940 1537 dbSNP
rs945404427 1541 dbSNP
rs7526404 1547 dbSNP
rs183955731 1548 dbSNP
rs934506306 1553 dbSNP
rs1186726831 1554 dbSNP
rs1360985579 1558 dbSNP
rs1415582324 1562 dbSNP
rs976077362 1566 dbSNP
rs1354520859 1568 dbSNP
rs1231286317 1572 dbSNP
rs553002831 1577 dbSNP
rs910792944 1578 dbSNP
rs1485685940 1580 dbSNP
rs984969019 1582 dbSNP
rs536052501 1583 dbSNP
rs952285762 1591 dbSNP
rs567169318 1597 dbSNP
rs1443651301 1602 dbSNP
rs1211091692 1604 dbSNP
rs1256443269 1607 dbSNP
rs1484894385 1608 dbSNP
rs978563725 1615 dbSNP
rs947310892 1617 dbSNP
rs1470027392 1619 dbSNP
rs1026064171 1621 dbSNP
rs368144673 1637 dbSNP
rs537384139 1638 dbSNP
rs1344919548 1643 dbSNP
rs991570436 1644 dbSNP
rs12087326 1652 dbSNP
rs1012519208 1666 dbSNP
rs1035425442 1669 dbSNP
rs137933418 1670 dbSNP
rs961739160 1674 dbSNP
rs1349406129 1676 dbSNP
rs1234472019 1686 dbSNP
rs868549492 1688 dbSNP
rs1345354015 1692 dbSNP
rs377075966 1695 dbSNP
rs528042876 1704 dbSNP
rs114275786 1708 dbSNP
rs1180211373 1709 dbSNP
rs1249025379 1709 dbSNP
rs1358428058 1715 dbSNP
rs541220232 1717 dbSNP
rs1431601562 1746 dbSNP
rs1431820861 1747 dbSNP
rs1168719200 1748 dbSNP
rs772874732 1748 dbSNP
rs888701758 1748 dbSNP
rs1388210098 1749 dbSNP
rs1409220760 1749 dbSNP
rs1326768506 1752 dbSNP
rs1373154574 1757 dbSNP
rs11802192 1759 dbSNP
rs1041544027 1766 dbSNP
rs945491371 1767 dbSNP
rs142128046 1768 dbSNP
rs1414558456 1771 dbSNP
rs901157082 1782 dbSNP
rs1275574122 1785 dbSNP
rs1165663234 1806 dbSNP
rs1040425290 1809 dbSNP
rs943321208 1812 dbSNP
rs1193595098 1817 dbSNP
rs910822554 1829 dbSNP
rs780333392 1832 dbSNP
rs985000002 1849 dbSNP
rs1194157527 1850 dbSNP
rs1372793532 1850 dbSNP
rs561915167 1854 dbSNP
rs1165987496 1861 dbSNP
rs866218593 1863 dbSNP
rs1461855323 1870 dbSNP
rs561559913 1873 dbSNP
rs934746285 1874 dbSNP
rs1391576633 1877 dbSNP
rs930837107 1879 dbSNP
rs1295839569 1883 dbSNP
rs544465922 1885 dbSNP
rs1224818110 1890 dbSNP
rs1295460705 1905 dbSNP
rs972257505 1917 dbSNP
rs1042913648 1926 dbSNP
rs750648727 1929 dbSNP
rs1484347056 1933 dbSNP
rs1273143846 1935 dbSNP
rs1271897655 1937 dbSNP
rs769837737 1939 dbSNP
rs1486889722 1944 dbSNP
rs1228250175 1945 dbSNP
rs947207297 1947 dbSNP
rs531254219 1954 dbSNP
rs565412839 1959 dbSNP
rs991129450 1964 dbSNP
rs377666457 1984 dbSNP
rs191206585 1987 dbSNP
rs928315317 1990 dbSNP
rs1415671270 1992 dbSNP
rs79350350 1992 dbSNP
rs1383660366 1993 dbSNP
rs539318193 1993 dbSNP
rs1288790796 1994 dbSNP
rs1411458536 2006 dbSNP
rs1314346019 2008 dbSNP
rs757087566 2008 dbSNP
rs78611348 2008 dbSNP
rs879259358 2008 dbSNP
rs114856069 2011 dbSNP
rs1291945919 2011 dbSNP
rs1240414254 2013 dbSNP
rs1260173986 2019 dbSNP
rs1484934583 2025 dbSNP
rs371283348 2030 dbSNP
rs903098107 2032 dbSNP
rs150250650 2035 dbSNP
rs546518093 2037 dbSNP
rs1368412528 2043 dbSNP
rs1307358994 2046 dbSNP
rs1253968769 2049 dbSNP
rs1020559043 2050 dbSNP
rs998015950 2064 dbSNP
rs1159753031 2065 dbSNP
rs371711186 2065 dbSNP
rs952909772 2067 dbSNP
rs1350610689 2072 dbSNP
rs1375729278 2081 dbSNP
rs1266210436 2090 dbSNP
rs1029017953 2093 dbSNP
rs1392410018 2097 dbSNP
rs1040457462 2098 dbSNP
rs373199696 2108 dbSNP
rs1183116782 2122 dbSNP
rs12044864 2133 dbSNP
rs1049053153 2142 dbSNP
rs903276884 2150 dbSNP
rs1235456115 2152 dbSNP
rs930932654 2154 dbSNP
rs185263952 2162 dbSNP
rs972671244 2163 dbSNP
rs1266747398 2165 dbSNP
rs1249816083 2167 dbSNP
rs1437248505 2171 dbSNP
rs753453578 2178 dbSNP
rs1195012156 2180 dbSNP
rs557133734 2199 dbSNP
rs879735783 2204 dbSNP
rs1173520713 2214 dbSNP
rs1356578385 2215 dbSNP
rs1462864945 2215 dbSNP
rs1298098443 2218 dbSNP
rs1371859213 2222 dbSNP
rs938629495 2228 dbSNP
rs1304192107 2231 dbSNP
rs1218698076 2234 dbSNP
rs1232295273 2246 dbSNP
rs182120788 2248 dbSNP
rs1275453423 2249 dbSNP
rs564249112 2267 dbSNP
rs1309034957 2274 dbSNP
rs1205013920 2278 dbSNP
rs571519386 2285 dbSNP
rs991160378 2292 dbSNP
rs557725551 2308 dbSNP
rs958440673 2309 dbSNP
rs763574524 2311 dbSNP
rs1453276400 2312 dbSNP
rs978431815 2325 dbSNP
rs1229785157 2333 dbSNP
rs1421287638 2335 dbSNP
rs909008187 2336 dbSNP
rs1170246907 2337 dbSNP
rs1398585245 2337 dbSNP
rs967726962 2341 dbSNP
rs1327181456 2342 dbSNP
rs1387342653 2349 dbSNP
rs953022519 2350 dbSNP
rs1272117120 2352 dbSNP
rs1214233340 2365 dbSNP
rs141072291 2375 dbSNP
rs1020169867 2378 dbSNP
rs1215419162 2383 dbSNP
rs1295404720 2397 dbSNP
rs1467634681 2415 dbSNP
rs1218792408 2420 dbSNP
rs1243465425 2430 dbSNP
rs1485962553 2432 dbSNP
rs189856588 2436 dbSNP
rs998442441 2443 dbSNP
rs1476425002 2449 dbSNP
rs965166858 2452 dbSNP
rs1393768438 2455 dbSNP
rs1160200996 2460 dbSNP
rs1019045375 2469 dbSNP
rs1007683971 2477 dbSNP
rs975964733 2483 dbSNP
rs112773217 2485 dbSNP
rs1019843728 2491 dbSNP
rs1049555378 2508 dbSNP
rs994837002 2509 dbSNP
rs1345898475 2523 dbSNP
rs898084829 2524 dbSNP
rs1296593871 2525 dbSNP
rs548980395 2526 dbSNP
rs186395147 2546 dbSNP
rs141574430 2548 dbSNP
rs917382875 2550 dbSNP
rs1268136805 2556 dbSNP
rs1210286326 2557 dbSNP
rs12085915 2569 dbSNP
rs1214616630 2572 dbSNP
rs1259982297 2572 dbSNP
rs1260674616 2576 dbSNP
rs937114338 2582 dbSNP
rs1189160641 2596 dbSNP
rs894527306 2608 dbSNP
rs1472075416 2610 dbSNP
rs925713273 2618 dbSNP
rs1408731843 2619 dbSNP
rs1400249647 2622 dbSNP
rs530961341 2624 dbSNP
rs1313700715 2626 dbSNP
rs1416367415 2633 dbSNP
rs1313210393 2648 dbSNP
rs1274516599 2649 dbSNP
rs978847382 2653 dbSNP
rs1299133624 2661 dbSNP
rs1281270611 2665 dbSNP
rs1350759313 2668 dbSNP
rs768031392 2671 dbSNP
rs967045180 2677 dbSNP
rs1283413933 2678 dbSNP
rs1349544423 2678 dbSNP
rs1211198809 2686 dbSNP
rs1321283558 2689 dbSNP
rs1437605516 2698 dbSNP
rs913141094 2700 dbSNP
rs1055633425 2718 dbSNP
rs976661036 2719 dbSNP
rs181327816 2720 dbSNP
rs1018161477 2723 dbSNP
rs1379670717 2724 dbSNP
rs1435526862 2732 dbSNP
rs1174576889 2741 dbSNP
rs1213840924 2744 dbSNP
rs375393166 2748 dbSNP
rs778423035 2755 dbSNP
rs759752909 2765 dbSNP
rs1248174997 2771 dbSNP
rs1189916928 2778 dbSNP
rs1463302025 2788 dbSNP
rs1330774674 2789 dbSNP
rs1260646864 2804 dbSNP
rs754596078 2818 dbSNP
rs1484120419 2829 dbSNP
rs375780562 2831 dbSNP
rs1233549051 2837 dbSNP
rs940387164 2850 dbSNP
rs367874877 2871 dbSNP
rs1273937340 2874 dbSNP
rs1049178263 2880 dbSNP
rs897787471 2881 dbSNP
rs1037030903 2882 dbSNP
rs1274292707 2883 dbSNP
rs1197334409 2892 dbSNP
rs931770412 2897 dbSNP
rs147899377 2898 dbSNP
rs896053046 2900 dbSNP
rs1376174065 2906 dbSNP
rs1324707800 2908 dbSNP
rs1476907262 2912 dbSNP
rs1317921129 2917 dbSNP
rs1169383175 2919 dbSNP
rs965528397 2926 dbSNP
rs146492261 2929 dbSNP
rs1329249298 2935 dbSNP
rs1396021705 2938 dbSNP
rs1441085493 2948 dbSNP
rs937480896 2956 dbSNP
rs925709578 2961 dbSNP
rs1300124260 2966 dbSNP
rs977656129 2976 dbSNP
rs1301449095 2977 dbSNP
rs1229179941 2979 dbSNP
rs1271093900 2980 dbSNP
rs542577776 2982 dbSNP
rs766060172 2988 dbSNP
rs1217276574 2989 dbSNP
rs945710164 2991 dbSNP
rs1434699480 2994 dbSNP
rs1275664278 2997 dbSNP
rs912929090 3004 dbSNP
rs760205522 3005 dbSNP
rs1265388811 3019 dbSNP
rs1448918947 3021 dbSNP
rs1229134257 3022 dbSNP
rs965314348 3030 dbSNP
rs574099489 3031 dbSNP
rs1373380100 3045 dbSNP
rs1477409002 3054 dbSNP
rs750066982 3055 dbSNP
rs958823970 3060 dbSNP
rs985306672 3064 dbSNP
rs1461485150 3066 dbSNP
rs563584263 3074 dbSNP
rs1034837144 3087 dbSNP
rs952554342 3089 dbSNP
rs1318581238 3111 dbSNP
rs1340284226 3112 dbSNP
rs1398584658 3112 dbSNP
rs1295627387 3115 dbSNP
rs1336043055 3117 dbSNP
rs1028157156 3118 dbSNP
rs1371941607 3119 dbSNP
rs11206274 3121 dbSNP
rs962430380 3129 dbSNP
rs1443773564 3131 dbSNP
rs1253875106 3142 dbSNP
rs907029383 3152 dbSNP
rs1259378141 3156 dbSNP
rs1483237082 3156 dbSNP
rs1276712067 3165 dbSNP
rs1366141760 3167 dbSNP
rs1014949042 3173 dbSNP
rs1036268208 3175 dbSNP
rs1202858846 3181 dbSNP
rs190184206 3185 dbSNP
rs1417508829 3187 dbSNP
rs1004770857 3199 dbSNP
rs564572475 3207 dbSNP
rs558321625 3212 dbSNP
rs1048724506 3214 dbSNP
rs1269665123 3219 dbSNP
rs534946645 3242 dbSNP
rs900283990 3245 dbSNP
rs1285548020 3247 dbSNP
rs1351716417 3259 dbSNP
rs1040144732 3269 dbSNP
rs1282108697 3272 dbSNP
rs1483461757 3277 dbSNP
rs1245879468 3284 dbSNP
rs1385598793 3301 dbSNP
rs1342466252 3317 dbSNP
rs115002911 3319 dbSNP
rs1178663897 3333 dbSNP
rs1379189969 3335 dbSNP
rs545243287 3340 dbSNP
rs1001658911 3341 dbSNP
rs557009108 3345 dbSNP
rs1376433333 3348 dbSNP
rs1043607453 3361 dbSNP
rs945854259 3365 dbSNP
rs774329065 3369 dbSNP
rs1371507561 3378 dbSNP
rs891523073 3380 dbSNP
rs763333927 3381 dbSNP
rs186892818 3388 dbSNP
rs535415540 3391 dbSNP
rs1304518342 3407 dbSNP
rs1395228924 3408 dbSNP
rs1163308040 3409 dbSNP
rs958952733 3422 dbSNP
rs1481553084 3425 dbSNP
rs1199200681 3430 dbSNP
rs1236972952 3432 dbSNP
rs1437345127 3433 dbSNP
rs1195110843 3439 dbSNP
rs1425485079 3449 dbSNP
rs1432939563 3450 dbSNP
rs768519551 3452 dbSNP
rs1375169324 3455 dbSNP
rs1366385785 3457 dbSNP
rs1186718962 3460 dbSNP
rs1331272408 3463 dbSNP
rs1472801321 3469 dbSNP
rs1443282477 3476 dbSNP
rs1034460427 3477 dbSNP
rs1326790928 3481 dbSNP
rs1253618947 3482 dbSNP
rs1217722279 3487 dbSNP
rs1298835744 3494 dbSNP
rs981480404 3495 dbSNP
rs1437153589 3497 dbSNP
rs985336248 3508 dbSNP
rs1272443526 3523 dbSNP
rs1215070051 3525 dbSNP
rs1246810940 3532 dbSNP
rs1014730887 3534 dbSNP
rs931148407 3536 dbSNP
rs142460226 3540 dbSNP
rs1422026970 3546 dbSNP
rs1478387551 3550 dbSNP
rs1271531657 3552 dbSNP
rs1232840894 3555 dbSNP
rs1351495675 3561 dbSNP
rs1290596960 3565 dbSNP
rs972958458 3577 dbSNP
rs370462923 3583 dbSNP
rs887709731 3597 dbSNP
rs1349374178 3598 dbSNP
rs555915429 3603 dbSNP
rs549571819 3607 dbSNP
rs1014933750 3611 dbSNP
rs900149963 3616 dbSNP
rs1324738466 3624 dbSNP
rs1327160161 3633 dbSNP
rs1400424750 3634 dbSNP
rs145542161 3635 dbSNP
rs1315930152 3637 dbSNP
rs1235097391 3648 dbSNP
rs1289892677 3656 dbSNP
rs959990018 3660 dbSNP
rs1218913262 3668 dbSNP
rs1034571125 3674 dbSNP
rs1193458878 3677 dbSNP
rs756443410 3677 dbSNP
rs1163760441 3680 dbSNP
rs1261519999 3681 dbSNP
rs1476434735 3687 dbSNP
rs1001826955 3689 dbSNP
rs1413147462 3693 dbSNP
rs1403740177 3695 dbSNP
rs1161510952 3697 dbSNP
rs1457436912 3708 dbSNP
rs1361464731 3719 dbSNP
rs1413977668 3728 dbSNP
rs1338155121 3731 dbSNP
rs775388753 3732 dbSNP
rs1021819549 3733 dbSNP
rs902225060 3734 dbSNP
rs1175248513 3739 dbSNP
rs373252341 3741 dbSNP
rs368168677 3744 dbSNP
rs1285888629 3751 dbSNP
rs1353914177 3752 dbSNP
rs534158710 3755 dbSNP
rs1284248884 3756 dbSNP
rs773470436 3757 dbSNP
rs1188847828 3763 dbSNP
rs1237450628 3769 dbSNP
rs1200856429 3775 dbSNP
rs1471837131 3778 dbSNP
rs1453417578 3780 dbSNP
rs1040794615 3783 dbSNP
rs943687873 3794 dbSNP
rs1178971223 3795 dbSNP
rs914866133 3801 dbSNP
rs1251147890 3802 dbSNP
rs990788512 3821 dbSNP
rs1358379974 3828 dbSNP
rs1416028690 3829 dbSNP
rs1334707615 3834 dbSNP
rs889420624 3842 dbSNP
rs1330073014 3851 dbSNP
rs573407733 3857 dbSNP
rs927312593 3860 dbSNP
rs1310728297 3861 dbSNP
rs1377010533 3862 dbSNP
rs1238956654 3873 dbSNP
rs1049417433 3880 dbSNP
rs1222454106 3884 dbSNP
rs931286161 3885 dbSNP
rs919823962 3887 dbSNP
rs746129469 3888 dbSNP
rs981386976 3894 dbSNP
rs571795611 3901 dbSNP
rs939825370 3915 dbSNP
rs1177000747 3928 dbSNP
rs1397162424 3934 dbSNP
rs1465202950 3949 dbSNP
rs1478875344 3953 dbSNP
rs1172897679 3968 dbSNP
rs1275975818 3974 dbSNP
rs376804987 3986 dbSNP
rs1412627874 3989 dbSNP
rs1333349839 3992 dbSNP
rs1368231356 3994 dbSNP
rs1324614901 3996 dbSNP
rs1328841998 4000 dbSNP
rs983282249 4002 dbSNP
rs116246990 4015 dbSNP
rs1027598106 4017 dbSNP
rs960103870 4022 dbSNP
rs528774800 4025 dbSNP
rs1259347347 4028 dbSNP
rs1425537350 4034 dbSNP
rs980491134 4035 dbSNP
rs559588065 4036 dbSNP
rs539897709 4040 dbSNP
rs374978340 4044 dbSNP
rs548966962 4064 dbSNP
rs1452363448 4065 dbSNP
rs1452499049 4069 dbSNP
rs1198438307 4074 dbSNP
rs1010424800 4075 dbSNP
rs1393412937 4076 dbSNP
rs1476956255 4088 dbSNP
rs1172691320 4089 dbSNP
rs1193053219 4095 dbSNP
rs139615787 4105 dbSNP
rs1019382775 4106 dbSNP
rs1386936878 4108 dbSNP
rs1322549254 4110 dbSNP
rs1008015646 4124 dbSNP
rs151021887 4125 dbSNP
rs1054602436 4129 dbSNP
rs937609628 4139 dbSNP
rs1267230292 4144 dbSNP
rs1213835032 4160 dbSNP
rs927513317 4160 dbSNP
rs1288038732 4169 dbSNP
rs1045717911 4170 dbSNP
rs1195510713 4172 dbSNP
rs575597501 4175 dbSNP
rs1191431196 4177 dbSNP
rs76316041 4183 dbSNP
rs1162251592 4191 dbSNP
rs1221487462 4191 dbSNP
rs1346312041 4195 dbSNP
rs1302114647 4196 dbSNP
rs1299144191 4200 dbSNP
rs771491556 4204 dbSNP
rs578035016 4208 dbSNP
rs1366686150 4219 dbSNP
rs1286773462 4228 dbSNP
rs908005387 4229 dbSNP
rs1244216711 4239 dbSNP
rs1282521156 4240 dbSNP
rs558134347 4244 dbSNP
rs1217624231 4245 dbSNP
rs995550309 4263 dbSNP
rs898430290 4266 dbSNP
rs1335925304 4267 dbSNP
rs747368125 4271 dbSNP
rs1374805245 4277 dbSNP
rs1423870071 4277 dbSNP
rs1366238670 4278 dbSNP
rs112966861 4280 dbSNP
rs1450183257 4282 dbSNP
rs1421657941 4283 dbSNP
rs917781976 4284 dbSNP
rs1158888268 4287 dbSNP
rs1185063733 4288 dbSNP
rs1475198832 4294 dbSNP
rs1418298512 4297 dbSNP
rs974562688 4298 dbSNP
rs1403471744 4304 dbSNP
rs1395987972 4312 dbSNP
rs1238461154 4320 dbSNP
rs964630811 4324 dbSNP
rs1379222168 4334 dbSNP
rs1018865241 4338 dbSNP
rs1213431458 4346 dbSNP
rs1484874567 4365 dbSNP
rs1352678804 4367 dbSNP
rs541194597 4371 dbSNP
rs1280271410 4375 dbSNP
rs113234374 4380 dbSNP
rs1257568121 4380 dbSNP
rs1483514961 4380 dbSNP
rs201687451 4380 dbSNP
rs377059854 4380 dbSNP
rs1416961268 4381 dbSNP
rs1206430220 4382 dbSNP
rs1178635515 4385 dbSNP
rs1378576677 4389 dbSNP
rs1465925493 4393 dbSNP
rs1301662079 4400 dbSNP
rs1008604771 4401 dbSNP
rs6699257 4403 dbSNP
rs757498493 4404 dbSNP
rs938791113 4404 dbSNP
rs1330911216 4407 dbSNP
rs1213688167 4413 dbSNP
rs1374891651 4423 dbSNP
rs1388776109 4424 dbSNP
rs1020743476 4430 dbSNP
rs1312570941 4447 dbSNP
rs1379419023 4453 dbSNP
rs1285548965 4456 dbSNP
rs1319357731 4462 dbSNP
rs927369920 4466 dbSNP
rs980141525 4467 dbSNP
rs969102231 4471 dbSNP
rs914834753 4473 dbSNP
rs893534780 4474 dbSNP
rs1268473020 4478 dbSNP
rs1433034009 4480 dbSNP
rs1174868549 4486 dbSNP
rs1055036995 4504 dbSNP
rs1001679748 4508 dbSNP
rs371139105 4509 dbSNP
rs146187132 4510 dbSNP
rs181865197 4511 dbSNP
rs950079966 4512 dbSNP
rs568866587 4519 dbSNP
rs1281167905 4524 dbSNP
rs953788699 4524 dbSNP
rs528247043 4526 dbSNP
rs1257177779 4533 dbSNP
rs995186040 4545 dbSNP
rs1183617419 4552 dbSNP
rs1256801442 4558 dbSNP
rs1481899491 4561 dbSNP
rs1223306555 4569 dbSNP
rs1265708397 4577 dbSNP
rs189484036 4583 dbSNP
rs930723793 4600 dbSNP
rs1036689896 4603 dbSNP
rs570493203 4610 dbSNP
rs920656074 4611 dbSNP
rs1321744267 4625 dbSNP
rs1291594775 4629 dbSNP
rs1349463842 4657 dbSNP
rs1423008719 4662 dbSNP
rs1300989897 4679 dbSNP
rs896386719 4685 dbSNP
rs975015817 4694 dbSNP
rs1194155168 4696 dbSNP
rs1277562320 4697 dbSNP
rs1231004270 4700 dbSNP
rs1354656607 4702 dbSNP
rs1288728146 4703 dbSNP
rs113561284 4707 dbSNP
rs111524814 4708 dbSNP
rs1320703141 4710 dbSNP
rs113506067 4711 dbSNP
rs374093071 4711 dbSNP
rs1288528988 4715 dbSNP
rs1488855323 4718 dbSNP
rs1216517487 4725 dbSNP
rs1240915747 4736 dbSNP
rs1474071054 4742 dbSNP
rs1182479612 4743 dbSNP
rs11800869 4763 dbSNP
rs1441598249 4768 dbSNP
rs987371784 4772 dbSNP
rs534842134 4774 dbSNP
rs566039489 4776 dbSNP
rs1167383621 4779 dbSNP
rs372772854 4785 dbSNP
rs745779529 4799 dbSNP
rs1343316234 4801 dbSNP
rs1450170601 4802 dbSNP
rs1460069163 4807 dbSNP
rs568495597 4810 dbSNP
rs1381425049 4815 dbSNP
rs200596367 4816 dbSNP
rs750110072 4822 dbSNP
rs1160338151 4831 dbSNP
rs1354827864 4842 dbSNP
rs1421441464 4868 dbSNP
rs1282633122 4880 dbSNP
rs1444569824 4882 dbSNP
rs1044837860 4885 dbSNP
rs1211453664 4887 dbSNP
rs549305916 4888 dbSNP
rs1236959906 4889 dbSNP
rs1460086963 4894 dbSNP
rs1180709128 4896 dbSNP
rs767141026 4902 dbSNP
rs1177074611 4905 dbSNP
rs184751614 4909 dbSNP
rs1405531364 4916 dbSNP
rs761608289 4926 dbSNP
rs1211497766 4928 dbSNP
rs1404717911 4929 dbSNP
rs958037631 4930 dbSNP
rs934924571 4933 dbSNP
rs1033430024 4943 dbSNP
rs912789423 4958 dbSNP
rs569976023 4970 dbSNP
rs986984790 4974 dbSNP
rs1377128369 4975 dbSNP
rs1441031931 4980 dbSNP
rs1278087653 4981 dbSNP
rs1347646944 4992 dbSNP
rs191111152 4992 dbSNP
rs1028081501 5009 dbSNP
rs1278584165 5011 dbSNP
rs533284280 5015 dbSNP
rs1321467536 5041 dbSNP
rs974261613 5044 dbSNP
rs141605685 5046 dbSNP
rs1314864062 5047 dbSNP
rs1179948880 5049 dbSNP
rs751285552 5053 dbSNP
rs1387215464 5060 dbSNP
rs1173061010 5062 dbSNP
rs1003819522 5063 dbSNP
rs1014473765 5068 dbSNP
rs896421059 5080 dbSNP
rs1034878780 5092 dbSNP
rs886652963 5095 dbSNP
rs1408996820 5103 dbSNP
rs376782308 5110 dbSNP
rs1333154276 5112 dbSNP
rs757036542 5128 dbSNP
rs1437687707 5135 dbSNP
rs1283064545 5156 dbSNP
rs1344131816 5158 dbSNP
rs1393982911 5171 dbSNP
rs1001997606 5189 dbSNP
rs1455685212 5199 dbSNP
rs1338893125 5205 dbSNP
rs1194292917 5206 dbSNP
rs1362353964 5209 dbSNP
rs1159099823 5211 dbSNP
rs527442629 5212 dbSNP
rs1267921384 5223 dbSNP
rs80041413 5228 dbSNP
rs1039097621 5234 dbSNP
rs1191167913 5236 dbSNP
rs115086808 5246 dbSNP
rs1248280234 5247 dbSNP
rs1206471346 5248 dbSNP
rs1484775343 5250 dbSNP
rs1154 5254 dbSNP
rs555900751 5255 dbSNP
rs987281710 5263 dbSNP
rs189267230 5267 dbSNP
rs945279342 5268 dbSNP
rs1225400682 5272 dbSNP
rs60004084 5277 dbSNP
rs912820198 5282 dbSNP
rs1357235740 5286 dbSNP
rs987016813 5289 dbSNP
rs1232224241 5293 dbSNP
rs1489817736 5294 dbSNP
rs1218658679 5300 dbSNP
rs1370260558 5300 dbSNP
rs1263872143 5307 dbSNP
rs1427869052 5325 dbSNP
rs1190343902 5326 dbSNP
rs1369704711 5328 dbSNP
rs56186476 5330 dbSNP
rs1383776206 5331 dbSNP
rs1384129534 5331 dbSNP
rs771221614 5340 dbSNP
rs1421946634 5345 dbSNP
rs1383331171 5354 dbSNP
rs1299322825 5360 dbSNP
rs921468987 5361 dbSNP
rs1381056030 5366 dbSNP
rs533631174 5368 dbSNP
rs139731316 5371 dbSNP
rs980477192 5372 dbSNP
rs974248231 5374 dbSNP
rs541884618 5380 dbSNP
rs1453284484 5387 dbSNP
rs1024429725 5405 dbSNP
rs377594265 5420 dbSNP
rs747384528 5427 dbSNP
rs962804419 5431 dbSNP
rs1390188681 5444 dbSNP
rs1015312472 5446 dbSNP
rs184753407 5447 dbSNP
rs1182564430 5467 dbSNP
rs1461434429 5467 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000371348.1 | 3UTR | UUUAAUGACACUACAUUUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
50 hsa-miR-584-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT133702 SKI SKI proto-oncogene 2 2
MIRT162603 CDC25A cell division cycle 25A 2 2
MIRT253722 ADRM1 adhesion regulating molecule 1 2 2
MIRT441657 DEK DEK proto-oncogene 2 2
MIRT465289 TRIB3 tribbles pseudokinase 3 2 2
MIRT466755 SYNGR2 synaptogyrin 2 2 2
MIRT472075 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT484818 ZNFX1 zinc finger NFX1-type containing 1 2 2
MIRT492058 TMEM59 transmembrane protein 59 2 2
MIRT493115 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 4
MIRT495251 SLC37A2 solute carrier family 37 member 2 2 2
MIRT502436 G3BP2 G3BP stress granule assembly factor 2 2 10
MIRT506333 NUPL2 nucleoporin like 2 2 4
MIRT511453 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 6
MIRT528878 ATF3 activating transcription factor 3 2 2
MIRT529262 TRIM4 tripartite motif containing 4 2 4
MIRT530762 ZNF582 zinc finger protein 582 2 2
MIRT532460 PLGRKT plasminogen receptor with a C-terminal lysine 2 2
MIRT532884 ZNF451 zinc finger protein 451 2 2
MIRT536526 KCTD10 potassium channel tetramerization domain containing 10 2 2
MIRT537512 FAM105A family with sequence similarity 105 member A 2 2
MIRT537543 ETS1 ETS proto-oncogene 1, transcription factor 2 2
MIRT541177 MSMO1 methylsterol monooxygenase 1 2 2
MIRT553497 TMEM55B phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 2 2
MIRT554381 SETD5 SET domain containing 5 2 2
MIRT568929 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT573385 GPR20 G protein-coupled receptor 20 2 2
MIRT573567 RANBP1 RAN binding protein 1 2 2
MIRT576078 Poteg POTE ankyrin domain family, member G 2 2
MIRT616473 CAV1 caveolin 1 2 2
MIRT619900 NPTXR neuronal pentraxin receptor 2 2
MIRT621122 PCNXL2 pecanex homolog 2 2 2
MIRT652694 THSD7A thrombospondin type 1 domain containing 7A 2 2
MIRT652901 SYT2 synaptotagmin 2 2 2
MIRT653356 SMG7 SMG7, nonsense mediated mRNA decay factor 2 2
MIRT653843 SHISA9 shisa family member 9 2 2
MIRT669211 CBX2 chromobox 2 2 2
MIRT684541 ZNF460 zinc finger protein 460 2 2
MIRT688018 GSN gelsolin 2 2
MIRT698896 SPTBN2 spectrin beta, non-erythrocytic 2 2 2
MIRT700786 PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2 2
MIRT708511 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT713659 PLCE1 phospholipase C epsilon 1 2 2
MIRT713768 METAP2 methionyl aminopeptidase 2 2 2
MIRT717156 LRRC3C leucine rich repeat containing 3C 2 2
MIRT720792 PRKRIP1 PRKR interacting protein 1 2 2
MIRT721095 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT721964 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT724716 CRAMP1L cramped chromatin regulator homolog 1 2 2
MIRT736350 GLI1 GLI family zinc finger 1 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-584 Olea europaea leaf extract NULL NULL Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
miR-584 Temozolomide approved 5394 Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-584 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-584 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-584 Cisplatin 5460033 NSC119875 approved resistant cell line (KYSE)
hsa-mir-584 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-mir-584 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-584 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-mir-584 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-584-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-584-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-miR-584-3p Docetaxel 148124 NSC628503 approved sensitive High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-584-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-584-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-584-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-584-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-584-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-584-3p Fluorouracil 3385 NSC19893 approved sensitive cell line (HCT15)
hsa-miR-584-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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