pre-miRNA Information
pre-miRNA hsa-mir-3180-1   
Genomic Coordinates chr16: 14911220 - 14911313
Description Homo sapiens miR-3180-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-3180-2   
Genomic Coordinates chr16: 16309879 - 16309966
Description Homo sapiens miR-3180-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-3180-3   
Genomic Coordinates chr16: 18402178 - 18402271
Description Homo sapiens miR-3180-3 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3180-3p
Sequence 62| UGGGGCGGAGCUUCCGGAGGCC |83
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NRGN   
Synonyms RC3, hng
Description neurogranin
Transcript NM_001126181   
Other Transcripts NM_006176   
Expression
Putative miRNA Targets on NRGN
3'UTR of NRGN
(miRNA target sites are highlighted)
>NRGN|NM_001126181|3'UTR
   1 GCCAGAAGAACTGAGCATTTTCAAAGTTCCCGAGGAGAGATGGATGCCGCGTCCCCTTCGCAGCGACGAGACTTCCCTGC
  81 CGTGTTTGTGACCCCCTCCTGCCCAGCAACCTGCCAGCTACAGGAGCCCCCTGCGTCCCAGAGACTCCCTCACCCAGGCA
 161 GGCTCCGTCGCGGAGTCGCTGAGTCCGTGCCCTTTTAGTTAGTTCTGCAGTCTAGTATGGTCCCCATTTGCCCTTCCACT
 241 CCACCCCACCCTAAACCATGCGCTCCCAATCTTCCTTCTTTTGCTTCTCGCCCACCTCTTCCCGCACCCAGCATGCAGCT
 321 CTGCCTCCGCAGCCTCAGTGCGCTTTCCTGCGCGCACTGCGGAGGGCGCCCTAAGCGTCACCCAAGCACACTCACTTAAA
 401 GAAAAAACGAGTTCTTTCGTTCTGTGCGCAGCTAAAAGGGGCGCCCTACATCTCCGTGCCACTCCCGCCCCAGCCTAGCC
 481 CCAAGACTTTGGATCCGGGGCGAGATGAAGGGAAGAGGGTTGTTTTGGTTTCGGACGACCCTTGCTCTGACCGGAAGAGA
 561 AGTCCCTATCCCACACCTGCCTGTCACGTTCCCTCCCCTTTCCCCAGCGCACTGTTGAGGGCAGCCTCTCCAGCTCTCTT
 641 GTTTATGCAAACGCCGAGCGCCTGGGAGGCTCGGTAGGAGGAGTCTTCCACGGCCCCGCCCCGCCCCTGTCGGTCCCGCC
 721 CTCCCCCCCGCCGGGCTCCTGGGGCTGTGGCCGAAAGGTTTCTGATCTCCGTGTGTGCATGTGACTGTGCTGGGTTGGAA
 801 TGTGAACAATAAAGAGGAATGTCCAAGTGAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ccGGAGGC-CUUCGA-GGCGGGGu 5'
            :||||| |   || ||||||| 
Target 5' caTCTCCGTGCCACTCCCGCCCCa 3'
449 - 472 156.00 -28.00
2
miRNA  3' ccGGAGGCCUUCGAGGCGGGGu 5'
            :||:|   :|| ||||||| 
Target 5' agTCTTCCACGGCCCCGCCCCg 3'
682 - 703 156.00 -26.80
3
miRNA  3' ccggaggcCUUCGAGGCGGGGu 5'
                  | |||||:|||:| 
Target 5' cccagcatGCAGCTCTGCCTCc 3'
307 - 328 130.00 -21.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20919575 175 COSMIC
COSN26548911 259 COSMIC
COSN26838950 503 COSMIC
COSN15059030 1155 COSMIC
COSN14944063 1164 COSMIC
COSN31577331 1268 COSMIC
COSN21582374 1282 COSMIC
COSN26636982 1323 COSMIC
COSN8735980 1359 COSMIC
COSN31609009 1411 COSMIC
COSN30163443 1424 COSMIC
COSN31589283 1477 COSMIC
COSN26555268 1483 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs12796778 6 dbSNP
rs1439251279 7 dbSNP
rs1197169962 11 dbSNP
rs1246529837 14 dbSNP
rs1455002367 15 dbSNP
rs770961283 18 dbSNP
rs1388869105 19 dbSNP
rs1429186811 20 dbSNP
rs774523388 25 dbSNP
rs922292830 28 dbSNP
rs1333556169 31 dbSNP
rs1398884095 31 dbSNP
rs1340877091 37 dbSNP
rs1330460658 38 dbSNP
rs1393570453 40 dbSNP
rs759786543 42 dbSNP
rs899424753 43 dbSNP
rs1323180623 48 dbSNP
rs767869540 51 dbSNP
rs933714485 52 dbSNP
rs1173615786 59 dbSNP
rs977120375 63 dbSNP
rs1433353812 64 dbSNP
rs924401277 66 dbSNP
rs996399803 80 dbSNP
rs1028679788 83 dbSNP
rs1231448547 90 dbSNP
rs774248515 91 dbSNP
rs1251018678 92 dbSNP
rs1438220396 94 dbSNP
rs1435944904 96 dbSNP
rs374936147 101 dbSNP
rs1486588390 112 dbSNP
rs1280424273 114 dbSNP
rs1020066745 119 dbSNP
rs967528965 121 dbSNP
rs1280969233 125 dbSNP
rs533238773 127 dbSNP
rs1312615457 128 dbSNP
rs1336751657 128 dbSNP
rs1032772190 138 dbSNP
rs948020052 138 dbSNP
rs948662539 141 dbSNP
rs1045057582 150 dbSNP
rs1405842047 157 dbSNP
rs1160560459 166 dbSNP
rs917140908 168 dbSNP
rs1416935617 174 dbSNP
rs970787745 175 dbSNP
rs906520068 198 dbSNP
rs1258223643 205 dbSNP
rs1214948424 220 dbSNP
rs1003569831 225 dbSNP
rs982520582 226 dbSNP
rs1167356628 234 dbSNP
rs907957609 248 dbSNP
rs1333622869 250 dbSNP
rs1025731683 252 dbSNP
rs1369249824 253 dbSNP
rs1443402228 258 dbSNP
rs1231911216 264 dbSNP
rs1389101309 270 dbSNP
rs1430610872 271 dbSNP
rs114074253 275 dbSNP
rs1330934922 276 dbSNP
rs1401509348 284 dbSNP
rs1393944852 285 dbSNP
rs570100413 288 dbSNP
rs537435660 295 dbSNP
rs1434723214 296 dbSNP
rs1418280396 297 dbSNP
rs1300134975 307 dbSNP
rs549348211 313 dbSNP
rs1474364623 320 dbSNP
rs920735582 322 dbSNP
rs932118363 332 dbSNP
rs1017525222 340 dbSNP
rs964306279 349 dbSNP
rs975651133 351 dbSNP
rs890692135 354 dbSNP
rs1008601959 358 dbSNP
rs1029891878 360 dbSNP
rs1041737528 361 dbSNP
rs955037881 362 dbSNP
rs902939537 363 dbSNP
rs999879464 364 dbSNP
rs1370299597 365 dbSNP
rs1450854290 370 dbSNP
rs1032706455 378 dbSNP
rs1463166462 386 dbSNP
rs977089087 399 dbSNP
rs1249524798 401 dbSNP
rs924348604 402 dbSNP
rs1408155043 413 dbSNP
rs1012696343 426 dbSNP
rs1168425596 429 dbSNP
rs957351194 432 dbSNP
rs1024266993 433 dbSNP
rs1195132343 444 dbSNP
rs1370902239 455 dbSNP
rs989974922 456 dbSNP
rs567521146 457 dbSNP
rs1204192946 464 dbSNP
rs1414998769 466 dbSNP
rs1306112079 470 dbSNP
rs1275799812 474 dbSNP
rs534827337 476 dbSNP
rs1045660054 477 dbSNP
rs552859932 492 dbSNP
rs1301290336 493 dbSNP
rs928576561 503 dbSNP
rs41302389 506 dbSNP
rs1167916466 512 dbSNP
rs1403976273 520 dbSNP
rs973506338 527 dbSNP
rs1356026426 530 dbSNP
rs538388570 532 dbSNP
rs1169192470 533 dbSNP
rs920661985 538 dbSNP
rs556627252 539 dbSNP
rs371101873 542 dbSNP
rs1050580554 543 dbSNP
rs574940484 545 dbSNP
rs887162303 548 dbSNP
rs912149701 555 dbSNP
rs527863911 556 dbSNP
rs944918118 562 dbSNP
rs1175113773 566 dbSNP
rs1038508827 567 dbSNP
rs867014592 575 dbSNP
rs997008516 576 dbSNP
rs1029860255 585 dbSNP
rs1278305158 585 dbSNP
rs542169303 587 dbSNP
rs894227021 592 dbSNP
rs1306614173 600 dbSNP
rs1012707937 606 dbSNP
rs1024527501 607 dbSNP
rs1308363181 609 dbSNP
rs1265986233 610 dbSNP
rs180899371 617 dbSNP
rs1004515809 620 dbSNP
rs1015490635 622 dbSNP
rs1314629101 623 dbSNP
rs1466163236 624 dbSNP
rs962066189 624 dbSNP
rs1031772111 625 dbSNP
rs1465171918 628 dbSNP
rs1420464602 637 dbSNP
rs1187595040 638 dbSNP
rs1410629308 649 dbSNP
rs957114418 655 dbSNP
rs764875888 660 dbSNP
rs1027778216 665 dbSNP
rs1475079303 671 dbSNP
rs750426828 676 dbSNP
rs113909381 678 dbSNP
rs1213610638 683 dbSNP
rs1483645943 685 dbSNP
rs986324029 691 dbSNP
rs1187578474 694 dbSNP
rs912017425 695 dbSNP
rs944995337 702 dbSNP
rs915687379 708 dbSNP
rs1474472290 711 dbSNP
rs978106854 713 dbSNP
rs149284924 714 dbSNP
rs1804829 722 dbSNP
rs1396486443 728 dbSNP
rs1457022326 735 dbSNP
rs1383658596 744 dbSNP
rs1287369887 746 dbSNP
rs1286544876 747 dbSNP
rs1404558835 755 dbSNP
rs1389001482 756 dbSNP
rs1163758530 768 dbSNP
rs1416119609 775 dbSNP
rs1461290866 775 dbSNP
rs1190245118 780 dbSNP
rs1396694165 780 dbSNP
rs981307186 781 dbSNP
rs1424860238 782 dbSNP
rs928502610 790 dbSNP
rs1261132105 814 dbSNP
rs559723607 816 dbSNP
rs61910622 828 dbSNP
rs1213267517 831 dbSNP
rs533557548 841 dbSNP
rs1245434813 847 dbSNP
rs1325726944 851 dbSNP
rs1047074162 854 dbSNP
rs908552469 855 dbSNP
rs1383484036 874 dbSNP
rs941400722 875 dbSNP
rs1324863947 876 dbSNP
rs1438195857 880 dbSNP
rs1290117413 885 dbSNP
rs1038856887 900 dbSNP
rs1804830 910 dbSNP
rs1329658985 912 dbSNP
rs1207834418 914 dbSNP
rs755643347 915 dbSNP
rs1165294448 916 dbSNP
rs1258605246 922 dbSNP
rs1465666609 923 dbSNP
rs948445793 925 dbSNP
rs1045588945 928 dbSNP
rs755584068 940 dbSNP
rs907052729 941 dbSNP
rs551625511 945 dbSNP
rs1193277457 949 dbSNP
rs563772291 950 dbSNP
rs530933973 956 dbSNP
rs1200537697 961 dbSNP
rs1004035005 966 dbSNP
rs899947276 972 dbSNP
rs1338504194 977 dbSNP
rs1015958561 997 dbSNP
rs1254949484 1002 dbSNP
rs1342287766 1014 dbSNP
rs1438261950 1017 dbSNP
rs1372645108 1026 dbSNP
rs549358447 1029 dbSNP
rs1387774328 1031 dbSNP
rs996933503 1035 dbSNP
rs1297009020 1040 dbSNP
rs779097337 1048 dbSNP
rs994841422 1051 dbSNP
rs1027622527 1055 dbSNP
rs1452645231 1055 dbSNP
rs1413298162 1059 dbSNP
rs11540078 1063 dbSNP
rs891353899 1065 dbSNP
rs1199816580 1068 dbSNP
rs986596737 1068 dbSNP
rs1248097372 1071 dbSNP
rs567581513 1072 dbSNP
rs1207244018 1073 dbSNP
rs534587988 1076 dbSNP
rs999075795 1082 dbSNP
rs1279004713 1103 dbSNP
rs1031951123 1106 dbSNP
rs546852608 1107 dbSNP
rs1373761631 1108 dbSNP
rs977615118 1110 dbSNP
rs1237851066 1112 dbSNP
rs1335569221 1117 dbSNP
rs1411708357 1123 dbSNP
rs892774650 1129 dbSNP
rs1412240280 1132 dbSNP
rs748918072 1146 dbSNP
rs989788791 1147 dbSNP
rs1173402823 1148 dbSNP
rs1404419112 1148 dbSNP
rs1350980094 1166 dbSNP
rs1184003594 1170 dbSNP
rs867468813 1170 dbSNP
rs1223011492 1171 dbSNP
rs770660590 1174 dbSNP
rs969803276 1180 dbSNP
rs1443689743 1181 dbSNP
rs981233364 1182 dbSNP
rs1313732209 1184 dbSNP
rs571391515 1187 dbSNP
rs950587892 1190 dbSNP
rs1351457268 1196 dbSNP
rs983761943 1198 dbSNP
rs1413426908 1199 dbSNP
rs1255027151 1200 dbSNP
rs1334835944 1206 dbSNP
rs538822734 1213 dbSNP
rs866412120 1216 dbSNP
rs941349394 1220 dbSNP
rs974107582 1223 dbSNP
rs1416866745 1225 dbSNP
rs1801526 1228 dbSNP
rs556641307 1231 dbSNP
rs568569669 1236 dbSNP
rs1482979179 1237 dbSNP
rs1237562850 1243 dbSNP
rs1175988428 1246 dbSNP
rs889144204 1250 dbSNP
rs1007551785 1253 dbSNP
rs1330275170 1255 dbSNP
rs932756709 1255 dbSNP
rs1175673233 1257 dbSNP
rs1051177085 1259 dbSNP
rs1359005322 1260 dbSNP
rs1393462714 1263 dbSNP
rs552779922 1267 dbSNP
rs1431727294 1271 dbSNP
rs1324727698 1272 dbSNP
rs1031773302 1277 dbSNP
rs554114488 1278 dbSNP
rs1393496045 1282 dbSNP
rs774239497 1285 dbSNP
rs957639537 1286 dbSNP
rs1406865391 1290 dbSNP
rs1414531704 1292 dbSNP
rs1167231849 1293 dbSNP
rs745648248 1299 dbSNP
rs1467702907 1300 dbSNP
rs1252774641 1303 dbSNP
rs990388131 1310 dbSNP
rs1296365370 1313 dbSNP
rs1369520114 1317 dbSNP
rs1387101382 1319 dbSNP
rs893424104 1326 dbSNP
rs1340161972 1335 dbSNP
rs368150967 1341 dbSNP
rs1229416302 1344 dbSNP
rs1370605914 1346 dbSNP
rs1302272923 1352 dbSNP
rs1011625079 1353 dbSNP
rs1229985203 1356 dbSNP
rs1274824011 1357 dbSNP
rs186131558 1359 dbSNP
rs541397323 1361 dbSNP
rs1168603506 1362 dbSNP
rs981126198 1365 dbSNP
rs1192541374 1376 dbSNP
rs928374879 1376 dbSNP
rs375902119 1378 dbSNP
rs1267725078 1381 dbSNP
rs578146571 1382 dbSNP
rs1206042997 1383 dbSNP
rs1036878369 1389 dbSNP
rs1035469061 1392 dbSNP
rs1451488286 1407 dbSNP
rs763643710 1412 dbSNP
rs1278665146 1413 dbSNP
rs1303153057 1417 dbSNP
rs931115816 1418 dbSNP
rs545574665 1423 dbSNP
rs753533481 1424 dbSNP
rs563783084 1425 dbSNP
rs1007976213 1426 dbSNP
rs1408251703 1434 dbSNP
rs14599 1435 dbSNP
rs1177823219 1436 dbSNP
rs1168284105 1438 dbSNP
rs1426319109 1445 dbSNP
rs1176926526 1447 dbSNP
rs1471812374 1478 dbSNP
rs112693723 1482 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ccggaggccuucgaGGCGGGGu 5'
                        ||||||| 
Target 5' --------------CCGCCCCu 3'
1 - 8
2
miRNA  3' ccGGA-GGCC----UUCGAGGCGGGGU 5'
            ||| :|||    :  |||| ||||:
Target 5' ccCCUGUCGGUCCCGCCCUCCCCCCCG 3'
4 - 30
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903829
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / CTLTD_shCTL_a
Location of target site NM_006176 | 3UTR | CCCGCCCCGCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_006176 | 3UTR | CCCGCCCCGCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_006176 | 3UTR | CCCGCCCCGCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000412681.2 | 3UTR | CCGCCCCUGUCGGUCCCGCCCUCCCCCCCGCCGGGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
66 hsa-miR-3180-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT133792 SKI SKI proto-oncogene 2 2
MIRT146658 MINK1 misshapen like kinase 1 2 4
MIRT441337 C19orf26 CACN beta subunit associated regulatory protein 2 4
MIRT449088 XPO6 exportin 6 2 2
MIRT464967 TULP1 tubby like protein 1 2 6
MIRT471706 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT473252 MIDN midnolin 2 2
MIRT483494 STMN3 stathmin 3 2 4
MIRT483726 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT485684 CCDC64 BICD family like cargo adaptor 1 2 4
MIRT486046 WSCD1 WSC domain containing 1 2 4
MIRT486522 CLCN7 chloride voltage-gated channel 7 2 2
MIRT486779 SESTD1 SEC14 and spectrin domain containing 1 2 4
MIRT486852 DPF1 double PHD fingers 1 2 2
MIRT487035 C10orf55 chromosome 10 open reading frame 55 2 2
MIRT487082 C3orf36 chromosome 3 open reading frame 36 2 2
MIRT487284 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 4
MIRT487992 RXRB retinoid X receptor beta 2 2
MIRT488101 POU3F1 POU class 3 homeobox 1 2 2
MIRT488547 POU3F3 POU class 3 homeobox 3 2 8
MIRT488582 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488757 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT489217 ASCL2 achaete-scute family bHLH transcription factor 2 2 4
MIRT489350 SYNGR1 synaptogyrin 1 2 4
MIRT489385 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT489459 MSC musculin 2 2
MIRT489469 SLITRK5 SLIT and NTRK like family member 5 2 2
MIRT489749 TACC3 transforming acidic coiled-coil containing protein 3 2 2
MIRT490244 MFI2 melanotransferrin 2 2
MIRT490423 VPS51 VPS51, GARP complex subunit 2 4
MIRT490644 FEM1A fem-1 homolog A 2 2
MIRT491977 UNK unkempt family zinc finger 2 2
MIRT492469 RASD1 ras related dexamethasone induced 1 2 4
MIRT492837 NRGN neurogranin 2 2
MIRT492956 NEUROD2 neuronal differentiation 2 2 2
MIRT493002 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT493430 KCNK3 potassium two pore domain channel subfamily K member 3 2 2
MIRT493709 H2AFX H2A histone family member X 2 6
MIRT493886 FAM43A family with sequence similarity 43 member A 2 4
MIRT493955 ENG endoglin 2 2
MIRT500168 MSI1 musashi RNA binding protein 1 2 2
MIRT500196 MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2 4
MIRT500366 ZNF385A zinc finger protein 385A 2 2
MIRT501159 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501698 PCGF3 polycomb group ring finger 3 2 6
MIRT512173 CASP16 caspase 16, pseudogene 2 6
MIRT512237 ATG2A autophagy related 2A 2 6
MIRT512879 PITX3 paired like homeodomain 3 2 2
MIRT531184 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT548362 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 4
MIRT569093 FSCN1 fascin actin-bundling protein 1 2 2
MIRT574133 MARVELD1 MARVEL domain containing 1 2 2
MIRT635542 LEPROTL1 leptin receptor overlapping transcript like 1 2 2
MIRT654098 RSBN1L round spermatid basic protein 1 like 2 2
MIRT664919 BHMT2 betaine--homocysteine S-methyltransferase 2 2 2
MIRT669843 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT670502 LYRM4 LYR motif containing 4 2 2
MIRT670526 SLC9A7 solute carrier family 9 member A7 2 2
MIRT670550 SHISA2 shisa family member 2 2 2
MIRT671031 PCDHB2 protocadherin beta 2 2 2
MIRT695219 SCAMP3 secretory carrier membrane protein 3 2 2
MIRT700129 RNF144B ring finger protein 144B 2 2
MIRT709280 MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT712750 GMDS GDP-mannose 4,6-dehydratase 2 2
MIRT720753 FAM193A family with sequence similarity 193 member A 2 2
MIRT724920 VPS18 VPS18, CORVET/HOPS core subunit 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3180 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3180 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3180 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3180 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180 Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (MGC803)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-3180 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-3180 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-3180 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-3180 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3180-3p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180-3p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3180-3p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3180-3p Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180-3p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (MGC803)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant Low Gastric Cancer cell line (MGC-803)
hsa-miR-3180-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-3180-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3180-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-3180-3p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-3180-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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