miRTarBase - #MIRT493177


—
pre-miRNA Information
pre-miRNA hsa-mir-3911   
Genomic Coordinates chr9: 127690687 - 127690795
Description Homo sapiens miR-3911 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3911
Sequence 12| UGUGUGGAUCCUGGAGGAGGCA |33
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
431152 7 ClinVar
COSM3847691 15 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs943029638 2 dbSNP
rs780635543 3 dbSNP
rs371437556 6 dbSNP
rs1135401819 7 dbSNP
rs748706130 14 dbSNP
rs1403241180 15 dbSNP
rs779344153 17 dbSNP
rs755366929 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MKNK2   
Synonyms GPRK7, MNK2
Description MAP kinase interacting serine/threonine kinase 2
Transcript NM_199054   
Other Transcripts NM_017572   
Expression
Putative miRNA Targets on MKNK2
3'UTR of MKNK2
(miRNA target sites are highlighted)		 
>MKNK2|NM_199054|3'UTR
   1 CCCTCCCATCTCCCCTCTGTACATAGGTCACCCGTCCCCCAATCAAATCTAAAGGTTTTTTAAGCTATCGCCAGCCGGTG
  81 TCCAGCGGGCTGCCCCTCCTCTGCCTGGATTCCCAGGCACTAAGCTCAGCTGAGGGGGGTGTTTTATAGAAGGTTTTTGC
 161 TTTTGGGTTTTTTTTTTCCTGTTTCCACCCCTCCCCGTTATTTTTTCCTTTGGATGGTTAAAAGCATTGCAGGCACCCGG
 241 GAAGGTGAGCAGAGGGTAGGTGGGTGGGCTTGTCCCCTCCCCGGTCCCCCGCCCTGCTCACCTCTACTATGAAGGTGCCC
 321 CCAGGTCACCTGTGCTGCCCGCCATCTGCCCACGTGGCTTGCAGTGACTCAGGAGAGCAGGCCCACAGCGTTTGCCATCT
 401 TGCAGAGCTGGGGAGGGGCACAGGACCCTGCCCTCGTGTTCCCTCCCAGCCCGCAGTATTTCAGGGACAGGCTCTTCCCC
 481 TCTATCCCTCACCCTGAGAGCACCCCTGGTGGCTTGGTTGGGGAAGGGAGGGGCTGCCTGTCTCTGGAGGTGTCAGGCAG
 561 GCAGGTGGCAGGCAGCTCACCCACCCACCCCATGGGATCCCCCAGCCCTTCACCCGCGCCTGCCTTGTCCCCATGATAGT
 641 TGACAATCGGGGCTTCCTGCAAGGCCCGTCTGTCTGTCCAGGACTCCTGGTGGCCAGATTCGGCCTCCGACCTTGACCTT
 721 AAACTGCAGCTGACCCCAGGGGCTCGCCGCTGCCCCTCCCCTCCACACCAAGGCCTGAGACAGCAGGAGCCCCGCCTGGC
 801 CCGAAGCCGTTTCCACCGCAGCAGGCAGAGGGGCTGGACAGGCACTGTCAGCCAATGTGGGGGGTCCTGAAGACACCCCC
 881 TTGGGGCACCCGAGTGCCCCTTCTCAGGGCTCAGTCTGACCGTAGCCACGTCCTGCCTCGCGCCGCCCCTCGGGCCTGAC
 961 CTGGAAGCTCCGTCAGCTCCGTCCTTGTCCTTAGAGCTGAGCCCAGACCCCGGGGTCTGGCCGAATCCTCACCCCCAGGG
1041 CAGTGTTTTTGGTCTGCCACCTTCAGGAAAACGGCTGCGGCCTCGGCCTCCCTTCGGGCACCCAGGAATGCGGGGGTCTG
1121 CTCAGTCCCCCCACCCTCCATGCTCCAACCCCCGGGGGCTGCGGAGCCTGCTGCCCCCTCCCCGCGGGTGGGGACGTTCT
1201 ATGCAATACAGGGTTCCACTTTAGAAGTGCGCGCGGCTAGGGTCACCGCCCGCCCTTCCCGGCGCAGCCCCCGAGCTCCA
1281 CAGCTGGGGCAGCCCCTCTGGCTTCTAAATCCGCGGTCGGGATTCTTCCTCCTGTTTAGTTTTTTAGTTTTTCCTTAAAA
1361 AAAAACAACACATCGATGGACTTTGCTTCCCTGTTCTTGAAGAATACTTGAATGTCGGGGGGCCTGGGGGTGGGGGCCTC
1441 GGAGACCGTCTGCCTGGCCCTGCTGCCCCTCCTGAATCTCGTATGATGGTCACAGTCCGGTGGCCGTGGGGGTGCTCTGC
1521 CTTCCCTGGTCCCCACTGCCCATATCTGTGGACTGCCCCTTCCAAAGACCCCTGGGGGGGGTGGGGCATTCCGCCCACCC
1601 CTTTCCCCCATCACTTCTCGCCTGTCAGTGATTCCATGTTTCGTAACGGGGGATTCTCTGCCTTTTTGTATCAAAGAACA
1681 AGCAAATGGACCCCCGCCCGCTGCAGGCGCCCATAGCCATCGGGTCTCTAAAGCTGAGTGGCTAGCAGCGTTTGTTTGTT
1761 TGTTTTTTTTTTTTTTTCTGAAGGTGGGACAGTCACTTCCTCCTCCCTCCCCACCCCTGTCGCATCCACGTGCGACCTGG
1841 AGGACTGGTCAGAACCGTTACTGTGAATGAGTGAAGATCCTGGAGGACCCTGGGCCCCAGGCCAGCTCCCATCGCTGGGG
1921 GACGGTGAACGGCCATGTGTTAATGTTACGATGTTTTTAAAAGACAAAAAAAAAAAAAAAACCTCAAAAGTTTTTTTAAA
2001 GTGGGGGAAAAACATCCAAGCACTTTAATTCCAATGTACCAGGTGAACTGACGGAGCTCAGAAGTTTTCCTTTACACCAA
2081 CTGTCAATGCCGGAATTTTGTATTCTGTTTTGTAAAGATTTAATAAAAGTCAAAAAACTTGCAAAAAAAAAAAAAAAAAA
2161 AA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acGGAGGAGGUCCUAGGUGUGu 5'
            ||||| ||    ||||||| 
Target 5' ccCCTCC-CC----TCCACACc 3'
 753 - 769 153.00 -19.50
2 
miRNA  3' acggaGGAGGUCCUAGGUGUgu 5'
               || ||: | ||||||  
Target 5' cgcagCCCCCGAGCTCCACAgc 3'
 1263 - 1284 137.00 -19.00
3 
miRNA  3' acGGAGGAGGUCCUAGGUGUGu 5'
            ||||||||    ||| ||| 
Target 5' ttCCTCCTCC---CTCCCCACc 3'
 1797 - 1815 133.00 -21.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN18716316 17 COSMIC
COSN28860128 34 COSMIC
COSN31492673 74 COSMIC
COSN31613996 76 COSMIC
COSN31488511 112 COSMIC
COSN30161437 132 COSMIC
COSN30689602 148 COSMIC
COSN31588505 283 COSMIC
COSN31488286 286 COSMIC
COSN16004128 340 COSMIC
COSN19354862 467 COSMIC
COSN26466282 479 COSMIC
COSN31488607 490 COSMIC
COSN31546132 555 COSMIC
COSN31588210 556 COSMIC
COSN31577615 557 COSMIC
COSN17037386 596 COSMIC
COSN21284638 620 COSMIC
COSN20608887 671 COSMIC
COSN8605281 707 COSMIC
COSN31591598 808 COSMIC
COSN28821709 939 COSMIC
COSN23161763 1011 COSMIC
COSN26568643 1081 COSMIC
COSN31524344 1084 COSMIC
COSN31533416 1126 COSMIC
COSN31538295 1159 COSMIC
COSN26585077 1209 COSMIC
COSN31535764 1210 COSMIC
COSN31592929 1232 COSMIC
COSN31557109 1234 COSMIC
COSN30360509 1333 COSMIC
COSN30175798 1356 COSMIC
COSN9350539 1364 COSMIC
COSN26648868 1369 COSMIC
COSN7117720 1391 COSMIC
COSN31528083 1396 COSMIC
COSN28865388 1574 COSMIC
COSN28714898 1580 COSMIC
COSN8605280 1580 COSMIC
COSN31489586 1605 COSMIC
COSN31541580 1630 COSMIC
COSN26317765 1636 COSMIC
COSN31537684 1642 COSMIC
COSN31489381 1676 COSMIC
COSN1212505 1708 COSMIC
COSN30100970 1745 COSMIC
COSN26984685 1749 COSMIC
COSN26984687 1750 COSMIC
COSN15665235 1762 COSMIC
COSM5364773 1763 COSMIC
COSN18748040 1764 COSMIC
COSN27205800 1765 COSMIC
COSN20079569 1766 COSMIC
COSN6552043 1770 COSMIC
COSM1611887 1778 COSMIC
COSM8306942 1783 COSMIC
COSM5365736 1785 COSMIC
COSM4522362 1788 COSMIC
COSM7868607 1799 COSMIC
COSM9647890 1805 COSMIC
COSM5112369 1829 COSMIC
COSM8800726 1834 COSMIC
COSM7930134 1837 COSMIC
COSM6319134 1850 COSMIC
COSM993535 1855 COSMIC
COSM7552685 1856 COSMIC
COSM6392254 1861 COSMIC
COSM7614896 1866 COSMIC
COSM6393140 1874 COSMIC
COSN30184285 1917 COSMIC
COSN26984691 1918 COSMIC
COSN30184284 1918 COSMIC
COSN30472573 1919 COSMIC
COSN31578014 1950 COSMIC
COSN18741960 1965 COSMIC
COSN1212504 1966 COSMIC
COSN20115292 1966 COSMIC
COSN29517672 2081 COSMIC
rs2287002 793 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs776835752 2 dbSNP
rs768645967 3 dbSNP
rs1390184603 6 dbSNP
rs376995230 7 dbSNP
rs746953502 8 dbSNP
rs758295938 12 dbSNP
rs1464012804 13 dbSNP
rs372960808 14 dbSNP
rs183403205 15 dbSNP
rs377172658 16 dbSNP
rs574144480 19 dbSNP
rs771009548 19 dbSNP
rs1180284613 22 dbSNP
rs1444267541 24 dbSNP
rs1470437633 25 dbSNP
rs951206272 26 dbSNP
rs778591377 27 dbSNP
rs777357313 31 dbSNP
rs755430406 33 dbSNP
rs372961015 34 dbSNP
rs1306268864 36 dbSNP
rs932840593 37 dbSNP
rs1240607532 38 dbSNP
rs760869663 41 dbSNP
rs1217137706 42 dbSNP
rs11556610 44 dbSNP
rs763281532 47 dbSNP
rs1039043173 54 dbSNP
rs368914729 55 dbSNP
rs1432031375 65 dbSNP
rs1348607611 69 dbSNP
rs962692538 70 dbSNP
rs760308800 73 dbSNP
rs941331936 76 dbSNP
rs1001568830 77 dbSNP
rs907191442 78 dbSNP
rs1442696938 81 dbSNP
rs1045808641 86 dbSNP
rs1010242139 87 dbSNP
rs891964875 92 dbSNP
rs1469547136 93 dbSNP
rs1054667285 94 dbSNP
rs1371538356 97 dbSNP
rs1407100574 99 dbSNP
rs561755800 101 dbSNP
rs771771891 103 dbSNP
rs1396886536 110 dbSNP
rs546674948 111 dbSNP
rs570369154 119 dbSNP
rs950110604 120 dbSNP
rs1039675641 124 dbSNP
rs1344340403 126 dbSNP
rs1471634720 127 dbSNP
rs917368940 130 dbSNP
rs558167086 132 dbSNP
rs139225148 135 dbSNP
rs959485894 136 dbSNP
rs1203428328 137 dbSNP
rs528093437 139 dbSNP
rs979768773 140 dbSNP
rs1263350816 148 dbSNP
rs1268727790 153 dbSNP
rs1490549769 155 dbSNP
rs929751264 158 dbSNP
rs1417681513 159 dbSNP
rs1020576134 160 dbSNP
rs1171352455 165 dbSNP
rs1009213620 176 dbSNP
rs547551679 177 dbSNP
rs1491361883 178 dbSNP
rs3833279 178 dbSNP
rs397810390 178 dbSNP
rs749798491 178 dbSNP
rs778877956 178 dbSNP
rs534434781 181 dbSNP
rs1359195505 183 dbSNP
rs1029838659 184 dbSNP
rs1306224211 185 dbSNP
rs1309647229 186 dbSNP
rs1244215815 187 dbSNP
rs1291769688 187 dbSNP
rs1360753499 188 dbSNP
rs1224209492 189 dbSNP
rs1375442660 190 dbSNP
rs1240465465 193 dbSNP
rs3746099 196 dbSNP
rs548999745 197 dbSNP
rs1451620239 199 dbSNP
rs1451172786 207 dbSNP
rs973962078 217 dbSNP
rs563897812 224 dbSNP
rs1038583839 230 dbSNP
rs563645168 232 dbSNP
rs979962343 233 dbSNP
rs1342928651 237 dbSNP
rs971380329 238 dbSNP
rs1024218861 239 dbSNP
rs1366907450 241 dbSNP
rs950045977 244 dbSNP
rs1314763899 245 dbSNP
rs1455732467 247 dbSNP
rs1344624941 252 dbSNP
rs1383923962 252 dbSNP
rs1010188373 255 dbSNP
rs1403020751 256 dbSNP
rs1262757965 269 dbSNP
rs1056285111 272 dbSNP
rs1412244545 275 dbSNP
rs1183416273 277 dbSNP
rs891912980 279 dbSNP
rs3746098 282 dbSNP
rs1000392159 283 dbSNP
rs900644199 284 dbSNP
rs1418066975 288 dbSNP
rs1039300857 290 dbSNP
rs944905830 291 dbSNP
rs1467924657 299 dbSNP
rs1259709048 304 dbSNP
rs890709763 308 dbSNP
rs1050783379 309 dbSNP
rs967922095 315 dbSNP
rs1278368486 320 dbSNP
rs913852329 328 dbSNP
rs987736298 330 dbSNP
rs929615459 331 dbSNP
rs1029372120 335 dbSNP
rs918366955 339 dbSNP
rs997005870 340 dbSNP
rs1245017101 341 dbSNP
rs1359828419 343 dbSNP
rs762560276 344 dbSNP
rs974207940 350 dbSNP
rs941219129 353 dbSNP
rs533210139 354 dbSNP
rs1361522165 357 dbSNP
rs1479138845 361 dbSNP
rs1175341858 365 dbSNP
rs887329584 371 dbSNP
rs1416560538 377 dbSNP
rs1327243264 382 dbSNP
rs1354263458 383 dbSNP
rs115788085 384 dbSNP
rs1348685375 387 dbSNP
rs1310321765 389 dbSNP
rs778136794 390 dbSNP
rs979992972 396 dbSNP
rs189758206 402 dbSNP
rs1167099289 408 dbSNP
rs1024166300 411 dbSNP
rs1426434223 413 dbSNP
rs575432074 416 dbSNP
rs1205803952 426 dbSNP
rs988799132 429 dbSNP
rs1489678416 431 dbSNP
rs956215978 435 dbSNP
rs1033115343 436 dbSNP
rs116278638 438 dbSNP
rs770055354 439 dbSNP
rs1266715419 440 dbSNP
rs562146570 449 dbSNP
rs1221577972 452 dbSNP
rs1018229471 453 dbSNP
rs1303810380 471 dbSNP
rs1359895452 471 dbSNP
rs748609497 474 dbSNP
rs1293756865 478 dbSNP
rs1009063091 479 dbSNP
rs890740717 480 dbSNP
rs543846506 485 dbSNP
rs373731257 486 dbSNP
rs1343661708 487 dbSNP
rs1221593081 488 dbSNP
rs1303089493 494 dbSNP
rs1290011289 495 dbSNP
rs913796674 498 dbSNP
rs1190597972 503 dbSNP
rs1406012971 506 dbSNP
rs929648205 510 dbSNP
rs1190869825 511 dbSNP
rs1367991652 516 dbSNP
rs1306623878 517 dbSNP
rs988019536 521 dbSNP
rs1164729283 533 dbSNP
rs896787516 542 dbSNP
rs558092246 543 dbSNP
rs922253942 546 dbSNP
rs1317985248 547 dbSNP
rs1327219017 548 dbSNP
rs975145660 550 dbSNP
rs1299578300 553 dbSNP
rs1170650413 555 dbSNP
rs377483141 565 dbSNP
rs1016712433 568 dbSNP
rs927059160 570 dbSNP
rs572378967 571 dbSNP
rs1198059986 573 dbSNP
rs1357918640 573 dbSNP
rs1202847531 588 dbSNP
rs984266618 592 dbSNP
rs1044241012 593 dbSNP
rs949872229 599 dbSNP
rs1193897393 600 dbSNP
rs917186136 602 dbSNP
rs1480162852 603 dbSNP
rs1444318648 605 dbSNP
rs1014507697 606 dbSNP
rs1252129836 608 dbSNP
rs988665078 612 dbSNP
rs956077988 615 dbSNP
rs751657443 616 dbSNP
rs151164086 617 dbSNP
rs904578596 618 dbSNP
rs1236309926 619 dbSNP
rs965192420 621 dbSNP
rs1329190894 622 dbSNP
rs1043139780 623 dbSNP
rs1017689798 629 dbSNP
rs1461199799 631 dbSNP
rs535640176 633 dbSNP
rs1258939305 635 dbSNP
rs1391201839 642 dbSNP
rs1009094087 646 dbSNP
rs1397589623 648 dbSNP
rs954836017 649 dbSNP
rs1473582173 652 dbSNP
rs946511310 653 dbSNP
rs567061681 656 dbSNP
rs1403422519 657 dbSNP
rs1465392515 659 dbSNP
rs1303185736 665 dbSNP
rs1404022318 666 dbSNP
rs548800004 667 dbSNP
rs1328020793 668 dbSNP
rs1411111529 672 dbSNP
rs537100785 673 dbSNP
rs933907265 676 dbSNP
rs1322376099 679 dbSNP
rs994124399 679 dbSNP
rs922567132 681 dbSNP
rs1258169087 686 dbSNP
rs1337785085 687 dbSNP
rs569556609 699 dbSNP
rs551323245 701 dbSNP
rs1484117417 702 dbSNP
rs533287196 705 dbSNP
rs896822568 708 dbSNP
rs1038484621 709 dbSNP
rs1009645115 717 dbSNP
rs1418295637 718 dbSNP
rs1250884960 720 dbSNP
rs1379159241 723 dbSNP
rs1460225667 725 dbSNP
rs1197327240 730 dbSNP
rs1167945910 733 dbSNP
rs866126643 742 dbSNP
rs905635443 745 dbSNP
rs1262719939 746 dbSNP
rs375302836 748 dbSNP
rs559664322 749 dbSNP
rs1302885645 753 dbSNP
rs949905070 756 dbSNP
rs1259500951 757 dbSNP
rs1227151069 758 dbSNP
rs917051962 759 dbSNP
rs1220836985 760 dbSNP
rs1238880114 768 dbSNP
rs993022196 777 dbSNP
rs113813463 786 dbSNP
rs1052973353 787 dbSNP
rs75579352 792 dbSNP
rs2287002 793 dbSNP
rs979200923 794 dbSNP
rs200666864 797 dbSNP
rs73916836 802 dbSNP
rs1390507093 803 dbSNP
rs910658921 808 dbSNP
rs543562122 809 dbSNP
rs954869331 812 dbSNP
rs1294996563 813 dbSNP
rs1382289769 814 dbSNP
rs891919620 817 dbSNP
rs1052201657 818 dbSNP
rs1367738746 819 dbSNP
rs1244424505 820 dbSNP
rs1314891501 821 dbSNP
rs933867039 827 dbSNP
rs1223858288 830 dbSNP
rs112045798 833 dbSNP
rs1259235556 835 dbSNP
rs901056045 836 dbSNP
rs1209551700 840 dbSNP
rs1453048683 843 dbSNP
rs1364293320 846 dbSNP
rs1026446680 854 dbSNP
rs993680604 858 dbSNP
rs1183778250 865 dbSNP
rs1442506804 872 dbSNP
rs963999180 876 dbSNP
rs1166260087 880 dbSNP
rs1342877200 881 dbSNP
rs576448332 892 dbSNP
rs1242790778 897 dbSNP
rs1016501445 903 dbSNP
rs1039628071 909 dbSNP
rs181895797 912 dbSNP
rs1184380148 913 dbSNP
rs546159408 921 dbSNP
rs556605202 922 dbSNP
rs34824515 923 dbSNP
rs1013924727 926 dbSNP
rs142187689 929 dbSNP
rs1053400479 930 dbSNP
rs1270241279 936 dbSNP
rs929695457 937 dbSNP
rs191074909 939 dbSNP
rs904463719 940 dbSNP
rs574633835 941 dbSNP
rs1471943214 944 dbSNP
rs927496279 945 dbSNP
rs148663343 951 dbSNP
rs943378207 952 dbSNP
rs1021577152 956 dbSNP
rs1175826477 958 dbSNP
rs1360072049 963 dbSNP
rs556674656 968 dbSNP
rs987558431 970 dbSNP
rs534749032 971 dbSNP
rs1290488656 972 dbSNP
rs752648309 973 dbSNP
rs998388422 976 dbSNP
rs536760294 980 dbSNP
rs763447149 981 dbSNP
rs754805029 984 dbSNP
rs143988124 990 dbSNP
rs1482480691 996 dbSNP
rs1182227610 1003 dbSNP
rs1253585803 1004 dbSNP
rs963557598 1008 dbSNP
rs1016944831 1009 dbSNP
rs1479270933 1010 dbSNP
rs773584498 1011 dbSNP
rs888390566 1012 dbSNP
rs981017624 1015 dbSNP
rs969704115 1022 dbSNP
rs929643294 1023 dbSNP
rs1430541713 1025 dbSNP
rs1309964693 1028 dbSNP
rs1240554426 1032 dbSNP
rs1436030514 1039 dbSNP
rs1275598880 1051 dbSNP
rs1368105841 1053 dbSNP
rs1192612688 1054 dbSNP
rs1272440516 1055 dbSNP
rs1341342662 1067 dbSNP
rs1205722928 1072 dbSNP
rs1447612542 1072 dbSNP
rs918318521 1073 dbSNP
rs1022546274 1078 dbSNP
rs1479234465 1079 dbSNP
rs1013872173 1081 dbSNP
rs557496665 1082 dbSNP
rs895599194 1084 dbSNP
rs1031401699 1085 dbSNP
rs999113110 1088 dbSNP
rs904327297 1089 dbSNP
rs1404822996 1092 dbSNP
rs1268007043 1095 dbSNP
rs1324533566 1095 dbSNP
rs770387310 1096 dbSNP
rs1438406117 1108 dbSNP
rs377433648 1111 dbSNP
rs143739660 1112 dbSNP
rs139727878 1114 dbSNP
rs1299719131 1116 dbSNP
rs1353731373 1117 dbSNP
rs1208698297 1119 dbSNP
rs1364876106 1121 dbSNP
rs1452999475 1125 dbSNP
rs1051800546 1127 dbSNP
rs933293347 1129 dbSNP
rs1206398260 1131 dbSNP
rs1247799089 1132 dbSNP
rs988743733 1135 dbSNP
rs748498645 1140 dbSNP
rs576851473 1141 dbSNP
rs547719195 1145 dbSNP
rs1163886537 1149 dbSNP
rs1415991352 1151 dbSNP
rs1399206714 1152 dbSNP
rs12151339 1153 dbSNP
rs1322518175 1154 dbSNP
rs965197945 1154 dbSNP
rs1243920024 1157 dbSNP
rs1018089699 1159 dbSNP
rs1357763696 1159 dbSNP
rs529161642 1162 dbSNP
rs568179112 1163 dbSNP
rs1425778409 1167 dbSNP
rs1254744869 1176 dbSNP
rs1442372646 1181 dbSNP
rs1197351524 1182 dbSNP
rs549920236 1183 dbSNP
rs981433218 1185 dbSNP
rs1225230241 1186 dbSNP
rs1412935355 1187 dbSNP
rs1436386102 1195 dbSNP
rs1048363032 1201 dbSNP
rs531744334 1214 dbSNP
rs1395391299 1218 dbSNP
rs1270468706 1219 dbSNP
rs564591267 1222 dbSNP
rs1341801572 1224 dbSNP
rs1194812924 1229 dbSNP
rs969650354 1230 dbSNP
rs545836230 1231 dbSNP
rs1221132242 1232 dbSNP
rs1057232445 1233 dbSNP
rs527674710 1234 dbSNP
rs1438371631 1236 dbSNP
rs992478462 1236 dbSNP
rs959677268 1238 dbSNP
rs767976576 1242 dbSNP
rs536281963 1247 dbSNP
rs79401019 1248 dbSNP
rs575039600 1251 dbSNP
rs1021500184 1252 dbSNP
rs1174427865 1254 dbSNP
rs989031140 1260 dbSNP
rs1007392921 1261 dbSNP
rs889067540 1263 dbSNP
rs556502332 1264 dbSNP
rs369858557 1265 dbSNP
rs1468931398 1268 dbSNP
rs897794055 1272 dbSNP
rs780225358 1273 dbSNP
rs942087045 1274 dbSNP
rs1298722674 1276 dbSNP
rs1018121103 1283 dbSNP
rs985290757 1284 dbSNP
rs544769437 1286 dbSNP
rs377566110 1293 dbSNP
rs952528380 1294 dbSNP
rs1340694676 1300 dbSNP
rs1457974450 1301 dbSNP
rs909285044 1312 dbSNP
rs1045241603 1314 dbSNP
rs948205372 1315 dbSNP
rs778941100 1317 dbSNP
rs918188285 1318 dbSNP
rs1447616065 1319 dbSNP
rs1322149677 1321 dbSNP
rs1167812969 1322 dbSNP
rs992341298 1325 dbSNP
rs1026867500 1326 dbSNP
rs537784696 1328 dbSNP
rs1291471393 1329 dbSNP
rs570234378 1330 dbSNP
rs1389541537 1331 dbSNP
rs924263537 1341 dbSNP
rs1306129674 1344 dbSNP
rs977491932 1345 dbSNP
rs1228334571 1350 dbSNP
rs147462407 1352 dbSNP
rs142973467 1353 dbSNP
rs1442631224 1358 dbSNP
rs1298969107 1359 dbSNP
rs1035343320 1362 dbSNP
rs1379443247 1364 dbSNP
rs1002980293 1365 dbSNP
rs1044555889 1366 dbSNP
rs1488941529 1366 dbSNP
rs35697817 1366 dbSNP
rs866402296 1366 dbSNP
rs905582090 1366 dbSNP
rs200906398 1367 dbSNP
rs147832541 1371 dbSNP
rs1390678606 1373 dbSNP
rs573953418 1374 dbSNP
rs1162119030 1375 dbSNP
rs893298581 1383 dbSNP
rs539493435 1389 dbSNP
rs1021782099 1391 dbSNP
rs1327436902 1406 dbSNP
rs555183139 1407 dbSNP
rs1386986021 1413 dbSNP
rs774741920 1416 dbSNP
rs138838851 1417 dbSNP
rs1407866884 1418 dbSNP
rs553768710 1419 dbSNP
rs1312134757 1423 dbSNP
rs1159551440 1430 dbSNP
rs1322332995 1432 dbSNP
rs1247275307 1433 dbSNP
rs923548871 1441 dbSNP
rs769295692 1447 dbSNP
rs535769862 1448 dbSNP
rs1248360413 1449 dbSNP
rs1486826181 1450 dbSNP
rs976081994 1454 dbSNP
rs568325563 1455 dbSNP
rs997397798 1459 dbSNP
rs1409267561 1464 dbSNP
rs1457086966 1465 dbSNP
rs1160396956 1466 dbSNP
rs1347276445 1469 dbSNP
rs1181308581 1471 dbSNP
rs1446466669 1472 dbSNP
rs72981418 1475 dbSNP
rs531525000 1478 dbSNP
rs1006627108 1480 dbSNP
rs570905054 1481 dbSNP
rs552255354 1483 dbSNP
rs767318790 1489 dbSNP
rs1229204097 1490 dbSNP
rs1283429351 1497 dbSNP
rs186784239 1498 dbSNP
rs1355518231 1499 dbSNP
rs1255340524 1501 dbSNP
rs1446207997 1503 dbSNP
rs1483311736 1505 dbSNP
rs546737623 1506 dbSNP
rs918052467 1511 dbSNP
rs1248919745 1513 dbSNP
rs1472076735 1521 dbSNP
rs1056645906 1528 dbSNP
rs560127544 1537 dbSNP
rs1410636788 1539 dbSNP
rs924182092 1540 dbSNP
rs1176060601 1541 dbSNP
rs1452279876 1542 dbSNP
rs1437073810 1543 dbSNP
rs1306295156 1548 dbSNP
rs1036029626 1552 dbSNP
rs1369957514 1554 dbSNP
rs1410684309 1557 dbSNP
rs977145610 1558 dbSNP
rs1002519001 1562 dbSNP
rs1027195518 1567 dbSNP
rs1383783758 1569 dbSNP
rs1304713445 1570 dbSNP
rs1348528870 1571 dbSNP
rs1212881378 1575 dbSNP
rs968774031 1576 dbSNP
rs541789962 1577 dbSNP
rs1011278038 1578 dbSNP
rs985846621 1579 dbSNP
rs953197566 1580 dbSNP
rs892912794 1581 dbSNP
rs1053204829 1582 dbSNP
rs1241087161 1582 dbSNP
rs998994019 1582 dbSNP
rs1345152621 1587 dbSNP
rs902071606 1592 dbSNP
rs141972242 1593 dbSNP
rs1292756766 1596 dbSNP
rs28699386 1605 dbSNP
rs1236420977 1617 dbSNP
rs975910338 1619 dbSNP
rs910534059 1621 dbSNP
rs1049128630 1625 dbSNP
rs1274439831 1628 dbSNP
rs930695089 1631 dbSNP
rs1220290488 1634 dbSNP
rs148141649 1634 dbSNP
rs1470098018 1636 dbSNP
rs1163336072 1637 dbSNP
rs919367214 1641 dbSNP
rs972531342 1642 dbSNP
rs78908729 1643 dbSNP
rs1015242363 1645 dbSNP
rs145756453 1647 dbSNP
rs1165678470 1648 dbSNP
rs745582030 1648 dbSNP
rs887746719 1652 dbSNP
rs181808315 1653 dbSNP
rs970040381 1653 dbSNP
rs1227441501 1656 dbSNP
rs1353573085 1656 dbSNP
rs369535154 1658 dbSNP
rs896574381 1660 dbSNP
rs1289403609 1669 dbSNP
rs1247747467 1670 dbSNP
rs957090295 1691 dbSNP
rs1244945775 1693 dbSNP
rs1056593565 1695 dbSNP
rs1166013311 1696 dbSNP
rs998941659 1696 dbSNP
rs1315062853 1697 dbSNP
rs112052351 1699 dbSNP
rs553831931 1700 dbSNP
rs1340299773 1701 dbSNP
rs551864545 1704 dbSNP
rs1289970099 1708 dbSNP
rs1044343129 1709 dbSNP
rs535431147 1716 dbSNP
rs1320188586 1717 dbSNP
rs947083093 1719 dbSNP
rs1446609014 1721 dbSNP
rs574686029 1722 dbSNP
rs889396368 1723 dbSNP
rs556423027 1726 dbSNP
rs1351780852 1734 dbSNP
rs1244739317 1737 dbSNP
rs750858082 1740 dbSNP
rs765371228 1741 dbSNP
rs762098620 1745 dbSNP
rs773164801 1747 dbSNP
rs776513158 1749 dbSNP
rs189710910 1750 dbSNP
rs760646344 1751 dbSNP
rs775534389 1753 dbSNP
rs1347859127 1754 dbSNP
rs1162659508 1755 dbSNP
rs772198502 1757 dbSNP
rs923006707 1758 dbSNP
rs1197446073 1760 dbSNP
rs1386078064 1760 dbSNP
rs1165778330 1761 dbSNP
rs772090042 1761 dbSNP
rs113879060 1762 dbSNP
rs768851323 1762 dbSNP
rs1160266097 1763 dbSNP
rs778776283 1763 dbSNP
rs778790813 1763 dbSNP
rs768531523 1764 dbSNP
rs371996752 1765 dbSNP
rs748954560 1765 dbSNP
rs749989137 1765 dbSNP
rs1064543 1766 dbSNP
rs199520689 1766 dbSNP
rs758962026 1766 dbSNP
rs754191916 1767 dbSNP
rs766658300 1767 dbSNP
rs770435818 1767 dbSNP
rs748993743 1768 dbSNP
rs760780957 1768 dbSNP
rs777227384 1769 dbSNP
rs771997298 1770 dbSNP
rs773394924 1770 dbSNP
rs78772412 1770 dbSNP
rs1174124189 1771 dbSNP
rs761842021 1771 dbSNP
rs1187565102 1772 dbSNP
rs1427256994 1774 dbSNP
rs755591108 1774 dbSNP
rs1245523730 1775 dbSNP
rs80059214 1777 dbSNP
rs199956186 1778 dbSNP
rs749159900 1778 dbSNP
rs768586621 1778 dbSNP
rs769619109 1778 dbSNP
rs779962068 1778 dbSNP
rs780369910 1778 dbSNP
rs745462148 1779 dbSNP
rs780781119 1779 dbSNP
rs750140334 1780 dbSNP
rs77702918 1780 dbSNP
rs779451929 1780 dbSNP
rs1490633264 1781 dbSNP
rs758971359 1783 dbSNP
rs1293491984 1784 dbSNP
rs750685175 1785 dbSNP
rs199999661 1788 dbSNP
rs754117000 1789 dbSNP
rs1215854966 1790 dbSNP
rs1365374397 1791 dbSNP
rs764448127 1793 dbSNP
rs534046508 1799 dbSNP
rs1367212772 1800 dbSNP
rs755474968 1800 dbSNP
rs775781927 1802 dbSNP
rs1460680294 1806 dbSNP
rs1372538200 1807 dbSNP
rs1464388042 1807 dbSNP
rs1447190739 1808 dbSNP
rs1171188999 1811 dbSNP
rs1169163924 1813 dbSNP
rs772072153 1814 dbSNP
rs759534768 1815 dbSNP
rs1199419740 1816 dbSNP
rs1442055766 1819 dbSNP
rs773969028 1821 dbSNP
rs770791796 1822 dbSNP
rs1382114260 1826 dbSNP
rs749079374 1827 dbSNP
rs8106804 1829 dbSNP
rs544764852 1830 dbSNP
rs1333945544 1831 dbSNP
rs747651202 1833 dbSNP
rs148990484 1834 dbSNP
rs368172637 1836 dbSNP
rs746405864 1837 dbSNP
rs779102927 1838 dbSNP
rs1286263868 1840 dbSNP
rs1261890611 1841 dbSNP
rs1390647494 1849 dbSNP
rs1429767040 1851 dbSNP
rs1185011897 1852 dbSNP
rs757608154 1854 dbSNP
rs756411912 1856 dbSNP
rs559094668 1857 dbSNP
rs774315053 1858 dbSNP
rs1176268068 1859 dbSNP
rs1481064912 1861 dbSNP
rs766278176 1865 dbSNP
rs957040313 1867 dbSNP
rs762796024 1870 dbSNP
rs1453695369 1876 dbSNP
rs1289957267 1878 dbSNP
rs1364257931 1879 dbSNP
rs1418915986 1885 dbSNP
rs1250786187 1886 dbSNP
rs761381448 1887 dbSNP
rs1481954960 1888 dbSNP
rs371240957 1892 dbSNP
rs1204178529 1895 dbSNP
rs769367820 1896 dbSNP
rs1266215783 1900 dbSNP
rs747812171 1901 dbSNP
rs200582514 1903 dbSNP
rs776068762 1904 dbSNP
rs999005145 1906 dbSNP
rs1279117948 1909 dbSNP
rs768240128 1911 dbSNP
rs746537611 1913 dbSNP
rs779450696 1914 dbSNP
rs766505378 1916 dbSNP
rs757775037 1919 dbSNP
rs1215063575 1921 dbSNP
rs749601086 1922 dbSNP
rs376888914 1923 dbSNP
rs756358905 1924 dbSNP
rs1256143791 1927 dbSNP
rs530095197 1929 dbSNP
rs1480457489 1930 dbSNP
rs1258914919 1931 dbSNP
rs1418861772 1935 dbSNP
rs201290425 1949 dbSNP
rs1321439350 1950 dbSNP
rs1312385496 1951 dbSNP
rs1263070077 1953 dbSNP
rs1234693821 1958 dbSNP
rs1333323556 1959 dbSNP
rs1044645439 1963 dbSNP
rs1286677122 1964 dbSNP
rs75300603 1965 dbSNP
rs367880430 1966 dbSNP
rs889342150 1967 dbSNP
rs1027925560 1975 dbSNP
rs994799029 1977 dbSNP
rs1208552753 1978 dbSNP
rs1375735391 1981 dbSNP
rs1178162489 1982 dbSNP
rs1212665198 1982 dbSNP
rs1249125679 1982 dbSNP
rs1436627494 1982 dbSNP
rs1450940483 1982 dbSNP
rs1480541210 1982 dbSNP
rs544163225 1982 dbSNP
rs71652796 1982 dbSNP
rs754009805 1982 dbSNP
rs77340163 1982 dbSNP
rs897836195 1982 dbSNP
rs1354186478 1983 dbSNP
rs1443149599 1984 dbSNP
rs1375175458 1987 dbSNP
rs1359402087 1991 dbSNP
rs1331552001 1992 dbSNP
rs1448375254 1995 dbSNP
rs12460502 2002 dbSNP
rs10294 2006 dbSNP
rs1175082488 2008 dbSNP
rs1270214906 2009 dbSNP
rs563084452 2012 dbSNP
rs1466540292 2025 dbSNP
rs975970127 2034 dbSNP
rs1234976233 2035 dbSNP
rs1487706822 2038 dbSNP
rs962167527 2043 dbSNP
rs1014856002 2052 dbSNP
rs1379275740 2053 dbSNP
rs985079154 2057 dbSNP
rs1166825421 2062 dbSNP
rs1163796834 2065 dbSNP
rs1418807619 2067 dbSNP
rs1410755323 2070 dbSNP
rs939414041 2073 dbSNP
rs906648197 2076 dbSNP
rs551266455 2087 dbSNP
rs1371673034 2090 dbSNP
rs532661437 2091 dbSNP
rs1012196863 2092 dbSNP
rs1180678113 2098 dbSNP
rs1460149697 2100 dbSNP
rs113148657 2106 dbSNP
rs1242675661 2107 dbSNP
rs1274636032 2107 dbSNP
rs1333209882 2113 dbSNP
rs1213482103 2117 dbSNP
rs1274154533 2121 dbSNP
rs896605340 2125 dbSNP
rs1035051794 2126 dbSNP
rs1191590923 2128 dbSNP
rs1241652472 2130 dbSNP
rs1475778494 2130 dbSNP
rs1188550561 2136 dbSNP
rs1411873378 2137 dbSNP
rs1347804888 2138 dbSNP
rs1394860833 2138 dbSNP
rs1461077662 2138 dbSNP
rs1462962669 2142 dbSNP
rs1259447793 2143 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acGGAGGAGGUCCUAGGUGUGu 5'
            ||||| ||    ||||||| 
Target 5' ccCCUCC-CC----UCCACACc 3'
 		9 - 25
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000591601.1 | 3UTR | CGCCGCUGCCCCUCCCCUCCACACCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
HNSC -0.559 0.1 -0.214 0.32 7 Click to see details
THCA 0.606 0.2 0.800 0.1 4 Click to see details
BRCA 0.277 0.33 0.600 0.14 5 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
LUSC 0.098 0.45 -0.200 0.4 4 Click to see details
70 hsa-miR-3911 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT207399 MAT2A methionine adenosyltransferase 2A 2 6
MIRT284537 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT291946 TPM4 tropomyosin 4 2 2
MIRT293609 PVR poliovirus receptor 2 2
MIRT357688 PAIP2 poly(A) binding protein interacting protein 2 2 2
MIRT451607 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT452110 IFITM1 interferon induced transmembrane protein 1 2 2
MIRT457804 KLHL25 kelch like family member 25 2 2
MIRT462730 EFNB1 ephrin B1 2 2
MIRT463219 ZNF131 zinc finger protein 131 2 2
MIRT464141 VPS28 VPS28, ESCRT-I subunit 2 2
MIRT467582 SLC7A5 solute carrier family 7 member 5 2 6
MIRT470824 PLXND1 plexin D1 2 2
MIRT474230 LCLAT1 lysocardiolipin acyltransferase 1 2 2
MIRT478989 COLGALT1 collagen beta(1-O)galactosyltransferase 1 2 2
MIRT479462 CDK6 cyclin dependent kinase 6 2 2
MIRT483558 SYT2 synaptotagmin 2 2 2
MIRT484483 SLC9A1 solute carrier family 9 member A1 2 2
MIRT485224 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT490356 DPYSL5 dihydropyrimidinase like 5 2 4
MIRT493177 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT509802 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT511815 HDGF heparin binding growth factor 2 2
MIRT512254 ARPP19 cAMP regulated phosphoprotein 19 2 6
MIRT513025 GPT2 glutamic--pyruvic transaminase 2 2 2
MIRT519640 ZNF772 zinc finger protein 772 2 4
MIRT531178 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT537870 EDA2R ectodysplasin A2 receptor 2 2
MIRT551914 IGLON5 IgLON family member 5 2 2
MIRT558359 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT559771 URGCP-MRPS24 URGCP-MRPS24 readthrough 2 4
MIRT559813 ZNF83 zinc finger protein 83 2 2
MIRT561999 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT565754 SERTAD2 SERTA domain containing 2 2 2
MIRT569423 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT569845 RGS5 regulator of G protein signaling 5 2 2
MIRT606928 CDK15 cyclin dependent kinase 15 2 2
MIRT607616 TMEM130 transmembrane protein 130 2 4
MIRT607629 TRIOBP TRIO and F-actin binding protein 2 2
MIRT607885 SATB1 SATB homeobox 1 2 2
MIRT607942 SSX2 SSX family member 2 2 4
MIRT608017 CARNS1 carnosine synthase 1 2 4
MIRT608036 UBLCP1 ubiquitin like domain containing CTD phosphatase 1 2 2
MIRT608063 SSX2B SSX family member 2B 2 4
MIRT608558 SBK1 SH3 domain binding kinase 1 2 6
MIRT608915 NCDN neurochondrin 2 6
MIRT615876 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 4
MIRT618023 ELFN1 extracellular leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT620505 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT628101 IL1RAPL1 interleukin 1 receptor accessory protein like 1 2 2
MIRT628700 ZNF548 zinc finger protein 548 2 2
MIRT630658 POU2F1 POU class 2 homeobox 1 2 2
MIRT643508 ZNF28 zinc finger protein 28 2 2
MIRT646379 SLC22A6 solute carrier family 22 member 6 2 2
MIRT660041 C15orf61 chromosome 15 open reading frame 61 2 2
MIRT687700 KRR1 KRR1, small subunit processome component homolog 2 2
MIRT688858 CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 2 2
MIRT690443 REPIN1 replication initiator 1 2 2
MIRT690456 ZNF33A zinc finger protein 33A 2 2
MIRT693796 RHOG ras homolog family member G 2 2
MIRT694274 ZNF529 zinc finger protein 529 2 4
MIRT697697 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT700242 RCC2 regulator of chromosome condensation 2 2 2
MIRT701836 MRPL37 mitochondrial ribosomal protein L37 2 2
MIRT704255 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT707203 SDK2 sidekick cell adhesion molecule 2 2 2
MIRT710365 CREB5 cAMP responsive element binding protein 5 2 2
MIRT711943 WDFY1 WD repeat and FYVE domain containing 1 2 2
MIRT715496 MAZ MYC associated zinc finger protein 2 2
MIRT719250 MS4A1 membrane spanning 4-domains A1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-3911 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3911 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-3911 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-3911 Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3911 Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3911 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-mir-3911 Vincristine 5978 approved resistant cell line (W1)
hsa-mir-3911 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-miR-3911 Palbociclib 5330286 NSC758247 approved resistant tissue (breast cancer)
hsa-miR-3911 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3911 Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-3911 Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-3911 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-3911 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3911 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-3911 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

Error report submission