miRTarBase - #MIRT493250


—
pre-miRNA Information
pre-miRNA hsa-mir-642b   
Genomic Coordinates chr19: 45674932 - 45675008
Description Homo sapiens miR-642b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-642b-3p
Sequence 47| AGACACAUUUGGAGAGGGACCC |68
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24410683 6 COSMIC
COSN8407659 14 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs778534861 2 dbSNP
rs111664333 4 dbSNP
rs998995912 5 dbSNP
rs1206620651 6 dbSNP
rs1317907103 7 dbSNP
rs374751972 13 dbSNP
rs78902025 15 dbSNP
rs775648115 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MEF2D   
Synonyms -
Description myocyte enhancer factor 2D
Transcript NM_005920   
Expression
Putative miRNA Targets on MEF2D
3'UTR of MEF2D
(miRNA target sites are highlighted)		 
>MEF2D|NM_005920|3'UTR
   1 CGATTCCCACTCCCCTCCTCTCAGCCTCCCTGATGAAGAGTTGACAATCTCACCGCCCGCCCTTCCCTGCCCCGGGCTCC
  81 TCCCGCTCGACCCCCACTTCCTTTCTTGTGCTTCGTGTCCTGTTGACGGTTACATTTGTGTATAATTATTATATTATTAT
 161 TATTATTATTATATTTTTTTTAATTTGGATTCTCGCTTTGGAGAGGGGGATGCTCTCATCCCCTCTTTCTGTACCCCCCA
 241 CCATTTTCACTGGCTGGGGGGCTCTCTTTTTCGCGGGAAGGGGGGACACTTTGCACGTTGTACACATATGCTGCAGGAAG
 321 GGGGTGGGGGGCCCAATAAGGCCTTTGGGAAAGGACAGGTGCCGAGCCCTGCATGTGGAGCCCTCCCACCCCACCCCCAG
 401 ATAGAGGGAAATAACCAAAAAACTACCAAACAACAGAAACCCACACTCTAGACTGAAACCCCAAAGTGGGCTTGATGGGT
 481 GGGTTTGTGTTTCAAGGGGAAAGTGAGGCAGAGGTTCTGAAAAGGGTCTCTGTTTTTGTGTTCATGTAGCCATAGGCACA
 561 TGGAGCAGAATACTTAAGCCTGGCCCCCAAATGCCCCTGCACACACACGTGCCACACCTGCGCTGATTCTTGTGTGTGCT
 641 GCACCCCCAAGGTGTGTGGGTGCTGGCTGAGCTTTGGGCCGGGAAGGCAGCCTGGGAATCTGAGGCTGGAGACAGGGGTT
 721 TGAGGTGGGGGCCTCTCTGGAAGCACATTTGGAGGGAAAGACAAGAGAGCCATGAGGAGAGGGCTGAGGAGGGCAGAAGG
 801 GCTAGGCAGGGGGCAAATTGAGCCCCTCCCTTCCCCAGTTTTTCTCTAAGATATACAGTGCAATAGCTCCCCACCCCTCA
 881 GTTGACGCCAGCCCTGTAAAGCTGGCCACAGTGTGCAGGGAGAATGGGGAGAGGGTCTTCAGTGAGGTGGCTGGGGCGAG
 961 AGTCGGCCTGGACTTCCCTGGGGTGCTCCAGGCCAGAGCTCTTTCATTGGGGCGAGTGTGGTGAGGGGACGTCCTTGGTC
1041 TTGCACGCACACTACCTGGGGGAGTCAACACTGGGATGGTCTGTGGGGTGGGAGGGCCTACGGATGGGTCCGTAGAGGTC
1121 CCACCTCCCTCATTCCTCCTTGGCCCCTCTCCCTAGCTTCTCCTGTTAGCTCCTTCTGCTCCTGACCCCACCTCCTTGCT
1201 CTTGGCGCCCCTATTGTCTCTGGCTACCTCCTTGTCCCACCACCTCCAGGCTGCATCCCACCTTCCCTCTTGGCTACTGT
1281 AATTGTAAATAGCGACCTTTGGAAAACGTTAGCGGTGTAACAGTCCAGGAAACTGTTTTTTTTTGTTGTTGTTGTATTGA
1361 TATGAAATGAGATTCTATTTTTGTCAAAGTATATTGTAATAATAATGACTCAAACGGCCCGTACTGTACAGACGAGATTC
1441 TTCTGCTGTTGTTCTTGCTCCCCTCCCCTCCTCTGAGTCCGCCCCTCCCTGCTGCCTCCTCAGTGGGGCAGTGGGCAAGG
1521 GGCCCAGGGGCAGCCGAAGCACGGGGTCCTGAGACCTCAGGCAGGATTGGAGATCAAACCAGAGGGGGCAGGCCCCCAGC
1601 CTGCTCTCTAGGATCACCCCCCGCCCTAAGGGGCCTGGCCTGGGGTGACGTGGCCAGGCAGACTGTCTGCCCCACTCCTT
1681 CACACAAGCCCAGCTCCTCTGCCCAAGGGGTGCGGCGCCCCCTTGGGGTTTCCTCCCAGTTGGAGAGTAGAGTTAAGACA
1761 AGGCCCAGTTTTGTGTTAGCCGACCGTCTTTGCCCACCTCTATGACCCAGCCTCTTGCAGTATTCCCATACTTGATGCAG
1841 GGAAGGAACCAGAAGCAGAGGGGCCTCTACGCAGGTACACACGTGTACCTGAGTGTGTTCATGAGGGCATCTGGTGTTTA
1921 TGTGTCTGAGTGTAGCTTTGTATTTATGTGTGTGTGTGTGTGTATGTCTGATTGCACGGGTGTACTTTTGTATTTATGTG
2001 TGTGTGTGGTTGCACGGGTGTGCCTCTGTGTGTCTCTGACCCTGGCTGGGTGTGTGTGCAAATCTGTGTGACTGGAGCTC
2081 TAGGGGCATCTCTGTGTCTGAGTGTGCCTGGTGTGTGTTTACAAAGGGAGAGTTGGCTGCTCCAGCTCCACAGCCCTGGG
2161 ACCCCAACTCCTGTCTTCCCTGCTCCTTTCCCTGTGTTCACCCTCAGCTCTGACACATTGAACTGCAGTTGGGGGGATTG
2241 GCAGTTAGCCCTCTGTGCTTCTCCCTGCAGCCCTACCTCTGCCAAGGTCTCTCCCTCCAGGGACCTCTGCTTCCACCCAC
2321 ATATGTCCACTTAGTCACCCACACTTGACACAGTTCCTGGAGTACCCTCTTCCCCCAACCCCAGACCTGCTTTCAGAGCA
2401 AAACTCAAGTCCCTCTTCCTCCGTGAAGCTTCTCCCTCAGCTGAGCAGTGATCACTTACTCACTCTTAACCCCAATCCGC
2481 TGACTGGGTGGGGACAGCACGTCCAGCCTTCCCACCTCTCCTGCAGGCTTCTAGACGGAGTTTCAAAAACTGATGAGCCT
2561 CGATCCAGGGCTTGAAAGAAGCCAGGGTGTAATCTTGTTCATGCATGCGTCCCCAGAGCCTCGCCCAGTGCCTGGCACAT
2641 AGTAGGCACTCAATAAATGCTGAATGGGTGAATAGTTGAATGATAGGTGCTCAATAAATGAATGAATGGCCTTCCCTTCT
2721 CAGGCTATTCCCACCATTAGTCTGCCCACCTTTCTAGGCTGGGCTTGGCCACCATTAAACACGGGGTGGGGGTGAGGGCC
2801 CCTGCAATTCACGGTGCAATATTCACCAGTTTTGCCCTCTGCCTCATAAAGGCAAACCTGGCTTTTGATTACCATGTGTG
2881 GATGTTTCAGTGTCCTTTCTTCTCTGTCCCTGGGGATGGGGTGGTCTGTGAATATGTGACATTTCTGCAGTTCAGTATCC
2961 GAAGGTTTCTCTTGGGGGTAGGGGCTCCTGGGCGGCCAGATGAATGGGTCCCTGGGAACCCAGACCTCAGATGAGGACTT
3041 AATGTCTTCTTCCTCTCAAGCCAAATTCGCCTCCACCCACTCCCTCTGAAGAACTGGGCATTTGCCAAAGTAACCACTGG
3121 AGTCATCTAATGGCCCTCCCCCTCCCCAGGTTTCCCACAGCTTTCAGGGACAGTGGGCAAGAGGACACCCCCCCCCACCA
3201 CCTCAGTGGAACACACCATTCTCCCCCCCTCAACAGCACACTCAGTGCAGCAAGACTGACCCCTGACCCCCTCCCAGCCC
3281 TCCCTACCTTGGACAGGAAGGAAGTAATGCACCTTCTCTTGCTGATTATTTATTTGTTTGGAGAGACAGAAATGTAAAAG
3361 TGTATCTAGAAATATCTATATCTCTATATATTTTTAACTGACTCTTTGGAATCCCCTGGGGTGGGGTGAGGGGTAAGTTT
3441 AGGCTTTCGCGGAGGGGAGGAGACATGGAGCCTGGGAACTCCTTGTTCTCCCCTCTGCTGCCTCTCCCCACCCCTTAAAG
3521 CAGTTGGTAGAAGGAATGGTATTTGTATGGGGGGAGGGAGGCTGGAATGGAGAATCTGGATTCTCTCCTCTTCCCCATTC
3601 TCCAGAGGGAGGGAGGTGGTGAGGAAGAGGAAGGGAGGGGCAGGATGGGCCATGGAGGTGCCCCACCCCCACACCTGACA
3681 ATCACCCACACTCCTGGGGCTCTTCCTGGGTCCTGGGGCAGGGCGAGTCCAAGTGTGAGGCTGTTGATTTGTTTTCAATA
3761 TTTCTTTTCGTGCTGTATGGTGATGCTTTCTTAGTATTCTACACAATAAGAAAAGACAAAGTCCTCGAGATTCTTATGAG
3841 TTTTGTTTGAAAACTCTTTCACTATATTTGTTGTAAAGAGGTTTACTATTAAAAGAAAAAGAATACACGTTTCTGATACT
3921 TCGGAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccCAGGGAGAGGUUUACACAGa 5'
            || |||||    :|||||| 
Target 5' gtGTGCCTCT----GTGTGTCt 3'
 2018 - 2035 142.00 -18.00
2 
miRNA  3' cccagggagagguuUACACAGa 5'
                        ||||||| 
Target 5' ggcatctggtgtttATGTGTCt 3'
 1906 - 1927 140.00 -11.80
3 
miRNA  3' ccCAGGGAGAGGU--UUACACAga 5'
            || |:|:| :|   ||||||  
Target 5' gtGTACTTTTGTATTTATGTGTgt 3'
 1980 - 2003 134.00 -10.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31612436 1 COSMIC
COSN30488829 2 COSMIC
COSN30461943 12 COSMIC
COSN26574894 17 COSMIC
COSN30526219 22 COSMIC
COSN26984170 42 COSMIC
COSN26984172 54 COSMIC
COSN30578859 58 COSMIC
COSN30644210 59 COSMIC
COSN31494829 74 COSMIC
COSN30460357 80 COSMIC
COSN30472623 84 COSMIC
COSN26984169 85 COSMIC
COSN30126364 90 COSMIC
COSN30492214 105 COSMIC
COSN30498740 114 COSMIC
COSN30126611 153 COSMIC
COSN30126331 154 COSMIC
COSN31585964 155 COSMIC
COSN26669461 200 COSMIC
COSN16131744 203 COSMIC
COSN28785052 243 COSMIC
COSN31595586 273 COSMIC
COSN28662745 275 COSMIC
COSN31521593 286 COSMIC
COSN24298463 297 COSMIC
COSN30173722 364 COSMIC
COSN17038248 462 COSMIC
COSN17038246 466 COSMIC
COSN6003834 600 COSMIC
COSN5732278 646 COSMIC
COSN31540278 809 COSMIC
COSN30538937 893 COSMIC
COSN31610722 963 COSMIC
COSN31588336 967 COSMIC
COSN31537869 993 COSMIC
COSN31533207 996 COSMIC
COSN31539414 1030 COSMIC
COSN31542782 1034 COSMIC
COSN31594718 1148 COSMIC
COSN30542798 1231 COSMIC
COSN2511456 1246 COSMIC
COSN20095445 1335 COSMIC
COSN8636340 1342 COSMIC
COSN31583759 1418 COSMIC
COSN28138136 1421 COSMIC
COSN31960325 1641 COSMIC
COSN29325793 1927 COSMIC
COSN20095444 1946 COSMIC
COSN23240378 1947 COSMIC
COSN20090371 2476 COSMIC
COSN25813872 2766 COSMIC
COSN17181649 2816 COSMIC
COSN15337744 2889 COSMIC
COSN7178846 2961 COSMIC
COSN27944379 3032 COSMIC
COSN29418598 3066 COSMIC
COSN20772239 3194 COSMIC
COSN30172376 3209 COSMIC
COSN1090145 3223 COSMIC
COSN30163644 3260 COSMIC
COSN17038255 3268 COSMIC
COSN17038247 3269 COSMIC
COSN31481866 3345 COSMIC
COSN26638927 3596 COSMIC
COSN32082886 3627 COSMIC
COSN31601304 3660 COSMIC
COSN26638303 3724 COSMIC
COSN31607261 3769 COSMIC
COSN31481908 3827 COSMIC
COSN20866967 3910 COSMIC
rs1050316 2734 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs768342831 1 dbSNP
rs1286217916 2 dbSNP
rs977869257 10 dbSNP
rs982195577 11 dbSNP
rs746871461 12 dbSNP
rs779843419 13 dbSNP
rs758173418 14 dbSNP
rs1020757973 19 dbSNP
rs745340293 20 dbSNP
rs752818500 23 dbSNP
rs778319755 25 dbSNP
rs757735074 30 dbSNP
rs1239637719 35 dbSNP
rs767762458 41 dbSNP
rs553751129 54 dbSNP
rs1019364833 55 dbSNP
rs1356932160 56 dbSNP
rs958222401 58 dbSNP
rs541777657 59 dbSNP
rs1032937565 72 dbSNP
rs574607089 73 dbSNP
rs1324705034 74 dbSNP
rs997001817 74 dbSNP
rs1457057975 75 dbSNP
rs953840402 77 dbSNP
rs1381626602 82 dbSNP
rs1296976486 84 dbSNP
rs1159843927 85 dbSNP
rs1436040067 87 dbSNP
rs1028254937 88 dbSNP
rs537925147 96 dbSNP
rs995796738 108 dbSNP
rs1360057068 109 dbSNP
rs556209577 111 dbSNP
rs1329558113 114 dbSNP
rs1379286842 115 dbSNP
rs1240940158 122 dbSNP
rs898499198 125 dbSNP
rs1004211518 127 dbSNP
rs575019158 128 dbSNP
rs907327387 136 dbSNP
rs1041265669 150 dbSNP
rs1008216387 151 dbSNP
rs1239600623 153 dbSNP
rs1165568240 154 dbSNP
rs887106987 170 dbSNP
rs1047156433 172 dbSNP
rs1054719442 173 dbSNP
rs1174762044 173 dbSNP
rs748414721 173 dbSNP
rs1188672266 174 dbSNP
rs931383339 175 dbSNP
rs919991854 181 dbSNP
rs1275361178 182 dbSNP
rs1329356591 182 dbSNP
rs1438528834 182 dbSNP
rs1317129817 195 dbSNP
rs1216542224 205 dbSNP
rs1257459210 206 dbSNP
rs1197860113 208 dbSNP
rs747225123 210 dbSNP
rs1452830484 213 dbSNP
rs937827024 215 dbSNP
rs1291784340 217 dbSNP
rs966352532 218 dbSNP
rs1338705870 221 dbSNP
rs1191988596 225 dbSNP
rs912337990 227 dbSNP
rs1229294123 234 dbSNP
rs537925930 235 dbSNP
rs1301608114 236 dbSNP
rs1436189859 240 dbSNP
rs1324178991 241 dbSNP
rs1339717750 242 dbSNP
rs1398021166 259 dbSNP
rs1279877470 262 dbSNP
rs1340829576 263 dbSNP
rs1331982392 267 dbSNP
rs1243705196 268 dbSNP
rs1325946788 268 dbSNP
rs926569900 272 dbSNP
rs571059334 273 dbSNP
rs1168646550 274 dbSNP
rs1431142534 275 dbSNP
rs1392869788 281 dbSNP
rs1187172295 284 dbSNP
rs1171583094 286 dbSNP
rs981753303 286 dbSNP
rs1478157103 288 dbSNP
rs1028535342 296 dbSNP
rs1164323043 297 dbSNP
rs1359919517 299 dbSNP
rs1179427005 306 dbSNP
rs995349949 308 dbSNP
rs970407345 321 dbSNP
rs913557729 331 dbSNP
rs1205953794 332 dbSNP
rs150376931 332 dbSNP
rs1341928732 336 dbSNP
rs1245001703 337 dbSNP
rs72994638 344 dbSNP
rs1350777329 349 dbSNP
rs1238696037 356 dbSNP
rs958045808 361 dbSNP
rs907191526 363 dbSNP
rs1486425744 366 dbSNP
rs1200206737 374 dbSNP
rs1254458128 375 dbSNP
rs185375713 380 dbSNP
rs1218799293 384 dbSNP
rs1346013976 388 dbSNP
rs1276921334 389 dbSNP
rs1237393128 393 dbSNP
rs1350371821 394 dbSNP
rs1465451609 395 dbSNP
rs1045805175 397 dbSNP
rs1404012492 399 dbSNP
rs1309234776 400 dbSNP
rs1412242241 402 dbSNP
rs1373032246 408 dbSNP
rs1332970087 409 dbSNP
rs1032052304 410 dbSNP
rs1414635369 412 dbSNP
rs1448321422 415 dbSNP
rs1309834626 417 dbSNP
rs1233092274 423 dbSNP
rs1318078937 423 dbSNP
rs1426891697 436 dbSNP
rs1012918360 438 dbSNP
rs567012748 443 dbSNP
rs1347577266 452 dbSNP
rs1204614350 456 dbSNP
rs1237783223 462 dbSNP
rs1456536805 466 dbSNP
rs894644579 482 dbSNP
rs548225589 501 dbSNP
rs936174204 503 dbSNP
rs41267367 508 dbSNP
rs1041954595 510 dbSNP
rs1484652919 525 dbSNP
rs1020324911 528 dbSNP
rs1169580932 532 dbSNP
rs1470109009 532 dbSNP
rs1235766696 545 dbSNP
rs945041703 546 dbSNP
rs912198156 556 dbSNP
rs986550318 579 dbSNP
rs953815857 580 dbSNP
rs1299805915 583 dbSNP
rs1347837235 584 dbSNP
rs1224477754 586 dbSNP
rs921015953 600 dbSNP
rs1200697674 604 dbSNP
rs1443190980 606 dbSNP
rs532947520 608 dbSNP
rs536226236 609 dbSNP
rs887136608 613 dbSNP
rs1047061249 621 dbSNP
rs1015946842 622 dbSNP
rs995441805 623 dbSNP
rs982636482 625 dbSNP
rs898583835 632 dbSNP
rs1170707000 635 dbSNP
rs1024218604 636 dbSNP
rs568850006 644 dbSNP
rs1055877839 645 dbSNP
rs1354142225 647 dbSNP
rs1292336932 648 dbSNP
rs1368044233 652 dbSNP
rs1406040040 657 dbSNP
rs937882752 659 dbSNP
rs894584354 660 dbSNP
rs905009362 670 dbSNP
rs1033084136 678 dbSNP
rs1448174371 679 dbSNP
rs370193446 680 dbSNP
rs9970660 681 dbSNP
rs949296149 686 dbSNP
rs112673830 690 dbSNP
rs766287653 692 dbSNP
rs903327676 695 dbSNP
rs913796604 708 dbSNP
rs1478673765 712 dbSNP
rs1412581830 714 dbSNP
rs1421653225 715 dbSNP
rs58899958 716 dbSNP
rs987808723 716 dbSNP
rs1425853455 719 dbSNP
rs755979067 727 dbSNP
rs376909183 729 dbSNP
rs1161141428 734 dbSNP
rs936315948 736 dbSNP
rs1433293037 739 dbSNP
rs925058489 746 dbSNP
rs758257815 754 dbSNP
rs964583127 756 dbSNP
rs546428234 757 dbSNP
rs140369520 761 dbSNP
rs1239412566 762 dbSNP
rs771206851 762 dbSNP
rs1448561320 765 dbSNP
rs951648536 769 dbSNP
rs1239414690 776 dbSNP
rs560813326 782 dbSNP
rs1236635424 783 dbSNP
rs1050784705 791 dbSNP
rs1361268031 792 dbSNP
rs995948904 795 dbSNP
rs1464641477 797 dbSNP
rs768435728 800 dbSNP
rs1438523756 812 dbSNP
rs1158622340 813 dbSNP
rs1378967641 815 dbSNP
rs921038630 818 dbSNP
rs1160317599 821 dbSNP
rs1358886632 823 dbSNP
rs1446096923 826 dbSNP
rs1338933244 833 dbSNP
rs1383687242 845 dbSNP
rs74116849 846 dbSNP
rs1289876986 847 dbSNP
rs1352780582 851 dbSNP
rs1228383471 853 dbSNP
rs182605263 854 dbSNP
rs1277662907 857 dbSNP
rs1380636560 858 dbSNP
rs1310217321 867 dbSNP
rs1205236765 868 dbSNP
rs1243348561 873 dbSNP
rs1294769549 879 dbSNP
rs562526308 886 dbSNP
rs749986855 887 dbSNP
rs982664108 894 dbSNP
rs767009827 899 dbSNP
rs1024166388 910 dbSNP
rs1178905055 911 dbSNP
rs1459712100 918 dbSNP
rs532014362 919 dbSNP
rs949159882 920 dbSNP
rs991477750 923 dbSNP
rs1349218668 924 dbSNP
rs1274164222 926 dbSNP
rs958714123 933 dbSNP
rs1407026080 935 dbSNP
rs1225081407 937 dbSNP
rs892396698 957 dbSNP
rs761511955 958 dbSNP
rs1000256139 964 dbSNP
rs1196303281 965 dbSNP
rs936372418 968 dbSNP
rs1274503461 971 dbSNP
rs924953692 976 dbSNP
rs1183229074 978 dbSNP
rs1246608380 981 dbSNP
rs975595120 988 dbSNP
rs564093724 989 dbSNP
rs912287777 990 dbSNP
rs1477623265 997 dbSNP
rs1166365825 1006 dbSNP
rs773933296 1007 dbSNP
rs544732077 1013 dbSNP
rs58318768 1014 dbSNP
rs1348079168 1020 dbSNP
rs564761116 1021 dbSNP
rs1283701280 1025 dbSNP
rs1038537098 1026 dbSNP
rs1216482847 1027 dbSNP
rs974336437 1030 dbSNP
rs534098796 1031 dbSNP
rs1287068267 1038 dbSNP
rs879842980 1046 dbSNP
rs573602888 1047 dbSNP
rs763330663 1052 dbSNP
rs1034368692 1054 dbSNP
rs1191360607 1056 dbSNP
rs1374969568 1057 dbSNP
rs1475839116 1061 dbSNP
rs1271798432 1066 dbSNP
rs949872385 1069 dbSNP
rs1342392154 1071 dbSNP
rs775695606 1074 dbSNP
rs1303682609 1084 dbSNP
rs907290753 1086 dbSNP
rs1299445010 1087 dbSNP
rs1384847009 1088 dbSNP
rs555330859 1088 dbSNP
rs1397879172 1091 dbSNP
rs1319997592 1097 dbSNP
rs917187699 1098 dbSNP
rs1024362962 1101 dbSNP
rs1013459034 1102 dbSNP
rs1281934127 1104 dbSNP
rs991341905 1106 dbSNP
rs892300315 1110 dbSNP
rs958971594 1111 dbSNP
rs1052375288 1112 dbSNP
rs1488189326 1120 dbSNP
rs750320134 1124 dbSNP
rs1429265633 1127 dbSNP
rs770374747 1129 dbSNP
rs1447809188 1136 dbSNP
rs1187024055 1138 dbSNP
rs1170657734 1142 dbSNP
rs1241436209 1150 dbSNP
rs1431664653 1151 dbSNP
rs1446506234 1152 dbSNP
rs1164185487 1164 dbSNP
rs1379649547 1165 dbSNP
rs1451480125 1165 dbSNP
rs536932141 1173 dbSNP
rs568914168 1175 dbSNP
rs1192161503 1179 dbSNP
rs1395165574 1180 dbSNP
rs547789024 1186 dbSNP
rs1384427055 1190 dbSNP
rs1452686129 1199 dbSNP
rs550594739 1206 dbSNP
rs191700727 1207 dbSNP
rs942319738 1213 dbSNP
rs1262868834 1214 dbSNP
rs1351843353 1220 dbSNP
rs867809015 1224 dbSNP
rs538732960 1228 dbSNP
rs912317585 1237 dbSNP
rs1050800855 1243 dbSNP
rs571211115 1244 dbSNP
rs776913490 1250 dbSNP
rs1483128089 1255 dbSNP
rs996411451 1272 dbSNP
rs1230527844 1277 dbSNP
rs918744555 1283 dbSNP
rs974621107 1285 dbSNP
rs1311276477 1288 dbSNP
rs1038076669 1293 dbSNP
rs527856552 1294 dbSNP
rs186799231 1305 dbSNP
rs1046779554 1307 dbSNP
rs927497944 1308 dbSNP
rs980135121 1313 dbSNP
rs971380135 1314 dbSNP
rs1024434833 1317 dbSNP
rs1370452525 1319 dbSNP
rs1390234610 1333 dbSNP
rs1010306746 1335 dbSNP
rs41267365 1336 dbSNP
rs949904999 1336 dbSNP
rs1056125839 1337 dbSNP
rs1325943661 1338 dbSNP
rs1204476615 1339 dbSNP
rs1257582217 1339 dbSNP
rs778098196 1342 dbSNP
rs925855275 1343 dbSNP
rs1001081563 1344 dbSNP
rs11558893 1345 dbSNP
rs147940265 1345 dbSNP
rs1431080098 1346 dbSNP
rs1299998635 1347 dbSNP
rs1169509669 1348 dbSNP
rs1464687953 1348 dbSNP
rs978815117 1349 dbSNP
rs1377333013 1351 dbSNP
rs182209416 1354 dbSNP
rs967355032 1355 dbSNP
rs1404817903 1356 dbSNP
rs913340216 1356 dbSNP
rs1281778899 1360 dbSNP
rs1039991063 1363 dbSNP
rs1224418934 1365 dbSNP
rs1006552327 1386 dbSNP
rs954869262 1387 dbSNP
rs1473205552 1393 dbSNP
rs1029129494 1396 dbSNP
rs890774737 1399 dbSNP
rs1253289956 1407 dbSNP
rs1050831672 1409 dbSNP
rs1198281897 1412 dbSNP
rs1482708882 1413 dbSNP
rs576116511 1415 dbSNP
rs1488122469 1416 dbSNP
rs929743239 1417 dbSNP
rs1220072206 1420 dbSNP
rs1270860565 1421 dbSNP
rs1490448257 1421 dbSNP
rs1211958207 1422 dbSNP
rs918312619 1433 dbSNP
rs530705552 1434 dbSNP
rs941492002 1443 dbSNP
rs927603044 1448 dbSNP
rs1228892130 1449 dbSNP
rs1367906993 1453 dbSNP
rs1016913900 1454 dbSNP
rs1288617434 1455 dbSNP
rs1360158052 1458 dbSNP
rs562589214 1463 dbSNP
rs1216484662 1465 dbSNP
rs1005240931 1466 dbSNP
rs1358811514 1475 dbSNP
rs980757941 1486 dbSNP
rs971409586 1497 dbSNP
rs1293825148 1498 dbSNP
rs749152271 1501 dbSNP
rs1214845148 1503 dbSNP
rs1240085102 1512 dbSNP
rs116084080 1518 dbSNP
rs577284678 1519 dbSNP
rs1254945877 1523 dbSNP
rs1013924648 1525 dbSNP
rs1162270625 1528 dbSNP
rs1387673456 1534 dbSNP
rs148275247 1535 dbSNP
rs190375273 1536 dbSNP
rs1033469777 1538 dbSNP
rs1471083970 1542 dbSNP
rs1000712854 1543 dbSNP
rs1317198840 1561 dbSNP
rs1383466833 1563 dbSNP
rs1281971288 1565 dbSNP
rs779457515 1567 dbSNP
rs1386821475 1575 dbSNP
rs1318494207 1577 dbSNP
rs949928582 1583 dbSNP
rs968276924 1586 dbSNP
rs915725826 1592 dbSNP
rs1458212054 1597 dbSNP
rs562686238 1599 dbSNP
rs946044650 1600 dbSNP
rs1184930108 1601 dbSNP
rs1018217298 1609 dbSNP
rs1445765534 1615 dbSNP
rs913203179 1617 dbSNP
rs573512677 1618 dbSNP
rs891016316 1622 dbSNP
rs369566047 1623 dbSNP
rs987558354 1623 dbSNP
rs1405665129 1629 dbSNP
rs1468384610 1633 dbSNP
rs1183173850 1636 dbSNP
rs555193885 1641 dbSNP
rs1383612961 1648 dbSNP
rs896911599 1649 dbSNP
rs1441463512 1650 dbSNP
rs769296683 1660 dbSNP
rs1277681336 1666 dbSNP
rs933433961 1667 dbSNP
rs536995438 1671 dbSNP
rs941578211 1683 dbSNP
rs1209174105 1687 dbSNP
rs906007750 1693 dbSNP
rs1205094493 1699 dbSNP
rs575964986 1701 dbSNP
rs556922229 1702 dbSNP
rs1204495407 1708 dbSNP
rs1231638641 1712 dbSNP
rs1016533940 1713 dbSNP
rs1339885185 1714 dbSNP
rs538219515 1716 dbSNP
rs988811634 1717 dbSNP
rs143112998 1735 dbSNP
rs1409422485 1740 dbSNP
rs546140960 1749 dbSNP
rs1356232297 1755 dbSNP
rs926091722 1756 dbSNP
rs1442767541 1759 dbSNP
rs1170587816 1762 dbSNP
rs979238455 1764 dbSNP
rs746407270 1767 dbSNP
rs1025225054 1776 dbSNP
rs112456371 1781 dbSNP
rs1283497289 1782 dbSNP
rs1338223067 1786 dbSNP
rs534397439 1802 dbSNP
rs1274438247 1807 dbSNP
rs1034497119 1809 dbSNP
rs1001394860 1813 dbSNP
rs567163063 1819 dbSNP
rs1161917588 1831 dbSNP
rs1268698116 1835 dbSNP
rs1489955996 1842 dbSNP
rs1201917520 1845 dbSNP
rs1378462673 1849 dbSNP
rs955294494 1858 dbSNP
rs1166248458 1871 dbSNP
rs1029500545 1877 dbSNP
rs1302454507 1882 dbSNP
rs757678354 1882 dbSNP
rs548762981 1883 dbSNP
rs985541719 1884 dbSNP
rs530717368 1891 dbSNP
rs891717638 1892 dbSNP
rs1339460067 1896 dbSNP
rs1229848990 1899 dbSNP
rs554008601 1901 dbSNP
rs376450175 1902 dbSNP
rs1247072590 1907 dbSNP
rs1188962540 1914 dbSNP
rs1357875086 1919 dbSNP
rs1016707259 1920 dbSNP
rs1225219774 1920 dbSNP
rs1268427892 1920 dbSNP
rs1265010496 1922 dbSNP
rs1191303620 1924 dbSNP
rs1005699809 1932 dbSNP
rs1450138034 1934 dbSNP
rs1162895031 1938 dbSNP
rs1357001623 1944 dbSNP
rs397945978 1947 dbSNP
rs751938217 1948 dbSNP
rs933293270 1950 dbSNP
rs144936751 1952 dbSNP
rs1297220571 1960 dbSNP
rs1326546273 1964 dbSNP
rs1451321021 1964 dbSNP
rs1491483871 1964 dbSNP
rs187653349 1964 dbSNP
rs201586484 1964 dbSNP
rs558460420 1964 dbSNP
rs57351079 1964 dbSNP
rs1436110013 1966 dbSNP
rs1465479707 1968 dbSNP
rs896076447 1968 dbSNP
rs983670178 1968 dbSNP
rs1183086163 1971 dbSNP
rs1328498035 1975 dbSNP
rs1053355072 1977 dbSNP
rs1386657978 1978 dbSNP
rs149914103 1979 dbSNP
rs1363062179 1992 dbSNP
rs1451319763 1997 dbSNP
rs1304398024 1998 dbSNP
rs1468914713 1998 dbSNP
rs992477127 1998 dbSNP
rs145947955 2000 dbSNP
rs1398360672 2006 dbSNP
rs200396793 2008 dbSNP
rs1034118308 2009 dbSNP
rs565268959 2009 dbSNP
rs747391776 2009 dbSNP
rs533826187 2015 dbSNP
rs978758100 2016 dbSNP
rs904360096 2024 dbSNP
rs540413523 2026 dbSNP
rs1201005882 2028 dbSNP
rs1249769114 2032 dbSNP
rs1417180956 2038 dbSNP
rs1183737767 2040 dbSNP
rs1476190606 2041 dbSNP
rs1021919515 2054 dbSNP
rs1010068073 2059 dbSNP
rs1430859817 2060 dbSNP
rs943469694 2061 dbSNP
rs1271051773 2064 dbSNP
rs1297070204 2066 dbSNP
rs1224803408 2080 dbSNP
rs910600599 2081 dbSNP
rs763787173 2083 dbSNP
rs1390112742 2094 dbSNP
rs955201410 2108 dbSNP
rs1351482894 2111 dbSNP
rs574820482 2114 dbSNP
rs1281579007 2122 dbSNP
rs765283541 2129 dbSNP
rs1314122096 2132 dbSNP
rs933324587 2132 dbSNP
rs141115869 2142 dbSNP
rs1197476100 2158 dbSNP
rs1252339164 2163 dbSNP
rs1490117581 2164 dbSNP
rs961099014 2167 dbSNP
rs942070134 2168 dbSNP
rs1229362632 2170 dbSNP
rs1433362844 2178 dbSNP
rs554796691 2195 dbSNP
rs1402295997 2206 dbSNP
rs1370778808 2218 dbSNP
rs1341764683 2229 dbSNP
rs1171019943 2232 dbSNP
rs909295840 2233 dbSNP
rs1017024563 2234 dbSNP
rs1005193761 2235 dbSNP
rs538085889 2236 dbSNP
rs34924929 2237 dbSNP
rs970214589 2238 dbSNP
rs759628658 2243 dbSNP
rs561471579 2246 dbSNP
rs568925733 2250 dbSNP
rs992342768 2259 dbSNP
rs1230575859 2270 dbSNP
rs895983208 2272 dbSNP
rs1358599160 2274 dbSNP
rs576019780 2275 dbSNP
rs1369322485 2285 dbSNP
rs36023544 2286 dbSNP
rs545659156 2295 dbSNP
rs147783896 2313 dbSNP
rs1171781088 2320 dbSNP
rs552922526 2321 dbSNP
rs1478268593 2323 dbSNP
rs904752501 2331 dbSNP
rs1431183033 2333 dbSNP
rs1179846417 2336 dbSNP
rs1351977630 2343 dbSNP
rs1458654063 2344 dbSNP
rs1288484320 2348 dbSNP
rs1359998984 2349 dbSNP
rs1437413629 2365 dbSNP
rs955835905 2367 dbSNP
rs1043455326 2372 dbSNP
rs1472242463 2374 dbSNP
rs1030268836 2376 dbSNP
rs1243597544 2380 dbSNP
rs943350004 2382 dbSNP
rs1291846478 2384 dbSNP
rs1322087938 2385 dbSNP
rs868151234 2387 dbSNP
rs774289143 2388 dbSNP
rs180830950 2396 dbSNP
rs1208822356 2399 dbSNP
rs1241910634 2400 dbSNP
rs1444631141 2418 dbSNP
rs1051795945 2419 dbSNP
rs777214270 2422 dbSNP
rs566976361 2423 dbSNP
rs555159406 2428 dbSNP
rs972562887 2434 dbSNP
rs961610002 2444 dbSNP
rs768527204 2455 dbSNP
rs909761859 2461 dbSNP
rs1458967842 2462 dbSNP
rs1276852765 2463 dbSNP
rs1321308598 2464 dbSNP
rs900504582 2466 dbSNP
rs1450435969 2468 dbSNP
rs771168747 2475 dbSNP
rs76784967 2477 dbSNP
rs1022758813 2478 dbSNP
rs887882550 2479 dbSNP
rs1208959173 2486 dbSNP
rs1350431980 2488 dbSNP
rs111272476 2492 dbSNP
rs959750743 2498 dbSNP
rs551422910 2501 dbSNP
rs1483838953 2502 dbSNP
rs998996061 2504 dbSNP
rs1406159014 2507 dbSNP
rs11576224 2524 dbSNP
rs1160164849 2534 dbSNP
rs571599668 2536 dbSNP
rs1407977702 2537 dbSNP
rs376188339 2548 dbSNP
rs772375410 2555 dbSNP
rs1468269691 2562 dbSNP
rs1008012231 2564 dbSNP
rs1156713180 2587 dbSNP
rs1359685654 2589 dbSNP
rs889098156 2603 dbSNP
rs1441305426 2604 dbSNP
rs546928468 2606 dbSNP
rs56374142 2608 dbSNP
rs561328525 2609 dbSNP
rs779956273 2616 dbSNP
rs1220478681 2618 dbSNP
rs1278647682 2622 dbSNP
rs543263273 2623 dbSNP
rs531154732 2626 dbSNP
rs1471232257 2628 dbSNP
rs980201724 2636 dbSNP
rs769417829 2638 dbSNP
rs939836192 2641 dbSNP
rs968396796 2648 dbSNP
rs868560541 2650 dbSNP
rs1187024157 2652 dbSNP
rs909821619 2653 dbSNP
rs1265329579 2659 dbSNP
rs1207277699 2664 dbSNP
rs914345305 2668 dbSNP
rs1425952483 2678 dbSNP
rs1409362272 2681 dbSNP
rs988532996 2682 dbSNP
rs955866973 2684 dbSNP
rs775183372 2687 dbSNP
rs563889785 2694 dbSNP
rs948389342 2698 dbSNP
rs781059559 2700 dbSNP
rs1225993753 2709 dbSNP
rs992472505 2710 dbSNP
rs1343275586 2717 dbSNP
rs965021599 2724 dbSNP
rs1275000412 2725 dbSNP
rs1338170193 2727 dbSNP
rs959782043 2731 dbSNP
rs1050316 2734 dbSNP
rs978026784 2735 dbSNP
rs1344887273 2736 dbSNP
rs1206330277 2738 dbSNP
rs751109791 2743 dbSNP
rs1450154649 2744 dbSNP
rs1201263900 2764 dbSNP
rs1027064970 2782 dbSNP
rs1475106160 2783 dbSNP
rs887749398 2785 dbSNP
rs1430268156 2791 dbSNP
rs1162705200 2792 dbSNP
rs1448243819 2803 dbSNP
rs1406797127 2807 dbSNP
rs1323783766 2810 dbSNP
rs578193636 2812 dbSNP
rs777144213 2816 dbSNP
rs1007798478 2819 dbSNP
rs896571028 2824 dbSNP
rs1434184214 2834 dbSNP
rs1389267713 2835 dbSNP
rs1161123288 2839 dbSNP
rs758131334 2867 dbSNP
rs889336608 2869 dbSNP
rs1229781935 2874 dbSNP
rs1056590163 2875 dbSNP
rs1354660080 2882 dbSNP
rs1211895643 2883 dbSNP
rs1290896038 2894 dbSNP
rs938177461 2900 dbSNP
rs1206914799 2904 dbSNP
rs1249908177 2912 dbSNP
rs905468515 2920 dbSNP
rs1182901089 2921 dbSNP
rs1366554184 2923 dbSNP
rs1473639089 2928 dbSNP
rs1043962707 2936 dbSNP
rs1383818434 2937 dbSNP
rs1455256309 2945 dbSNP
rs1245242141 2949 dbSNP
rs1187054435 2950 dbSNP
rs1464685023 2960 dbSNP
rs1274706836 2961 dbSNP
rs1243060216 2966 dbSNP
rs1388710157 2967 dbSNP
rs947056977 2970 dbSNP
rs914209340 2972 dbSNP
rs752237928 2975 dbSNP
rs934437830 2978 dbSNP
rs1350240086 2985 dbSNP
rs1320468787 2993 dbSNP
rs1288506000 2994 dbSNP
rs552696535 2996 dbSNP
rs997432774 2999 dbSNP
rs745372452 3000 dbSNP
rs1203005820 3001 dbSNP
rs765641868 3006 dbSNP
rs1295019334 3008 dbSNP
rs1227226236 3010 dbSNP
rs1254035937 3016 dbSNP
rs1444019231 3017 dbSNP
rs976350376 3019 dbSNP
rs1036438041 3029 dbSNP
rs1365566266 3034 dbSNP
rs1471439219 3040 dbSNP
rs1290440623 3045 dbSNP
rs1160894482 3060 dbSNP
rs1434148193 3068 dbSNP
rs964553546 3069 dbSNP
rs1017951306 3070 dbSNP
rs1400706224 3073 dbSNP
rs939885756 3079 dbSNP
rs1335358947 3081 dbSNP
rs952048903 3083 dbSNP
rs888265606 3091 dbSNP
rs1290415085 3097 dbSNP
rs1048818013 3098 dbSNP
rs1223007990 3099 dbSNP
rs1254268481 3101 dbSNP
rs1200949159 3106 dbSNP
rs1249616295 3107 dbSNP
rs766639617 3108 dbSNP
rs948638296 3110 dbSNP
rs1252110913 3123 dbSNP
rs915794329 3138 dbSNP
rs142909571 3139 dbSNP
rs1166876100 3143 dbSNP
rs1173347875 3143 dbSNP
rs1468083961 3143 dbSNP
rs992503764 3146 dbSNP
rs1420607104 3148 dbSNP
rs188401177 3149 dbSNP
rs555071727 3156 dbSNP
rs1310186312 3157 dbSNP
rs1200968709 3158 dbSNP
rs1197082284 3160 dbSNP
rs1386364303 3168 dbSNP
rs1487775727 3187 dbSNP
rs1332882119 3190 dbSNP
rs1250720375 3193 dbSNP
rs993449385 3193 dbSNP
rs536342587 3194 dbSNP
rs1490680012 3195 dbSNP
rs541244820 3195 dbSNP
rs1035089918 3196 dbSNP
rs1271861194 3196 dbSNP
rs1390127383 3197 dbSNP
rs1393094475 3197 dbSNP
rs540111996 3197 dbSNP
rs1387444812 3198 dbSNP
rs1296890669 3201 dbSNP
rs1227155458 3203 dbSNP
rs1002805217 3204 dbSNP
rs374771003 3212 dbSNP
rs1297427130 3222 dbSNP
rs1217303751 3223 dbSNP
rs905333407 3226 dbSNP
rs892721156 3227 dbSNP
rs576199828 3228 dbSNP
rs557930375 3229 dbSNP
rs1423628475 3230 dbSNP
rs923034458 3230 dbSNP
rs1370428639 3231 dbSNP
rs1458540344 3242 dbSNP
rs977180087 3243 dbSNP
rs969321765 3252 dbSNP
rs1021809498 3254 dbSNP
rs943204627 3255 dbSNP
rs986238401 3261 dbSNP
rs1378303158 3268 dbSNP
rs953631877 3274 dbSNP
rs1226424586 3281 dbSNP
rs985026510 3284 dbSNP
rs1227398058 3289 dbSNP
rs1321954688 3289 dbSNP
rs539357806 3291 dbSNP
rs1465834951 3303 dbSNP
rs1429330081 3305 dbSNP
rs1243221444 3308 dbSNP
rs1483174401 3309 dbSNP
rs1180479870 3313 dbSNP
rs997506519 3319 dbSNP
rs1424671388 3321 dbSNP
rs897825708 3325 dbSNP
rs1015445111 3329 dbSNP
rs1409904909 3335 dbSNP
rs1026173347 3336 dbSNP
rs780627961 3348 dbSNP
rs565928328 3356 dbSNP
rs547034827 3362 dbSNP
rs1445646170 3365 dbSNP
rs1431860595 3366 dbSNP
rs960673260 3375 dbSNP
rs1424917585 3378 dbSNP
rs759782072 3382 dbSNP
rs1286103192 3384 dbSNP
rs887828790 3384 dbSNP
rs1228485088 3386 dbSNP
rs1200693635 3388 dbSNP
rs1277207857 3402 dbSNP
rs1312184070 3404 dbSNP
rs1208619220 3408 dbSNP
rs1239628894 3410 dbSNP
rs1048228917 3414 dbSNP
rs1181865164 3415 dbSNP
rs1249922954 3418 dbSNP
rs1035529625 3421 dbSNP
rs534985765 3422 dbSNP
rs1424545357 3423 dbSNP
rs567639447 3425 dbSNP
rs969964785 3426 dbSNP
rs1359630628 3429 dbSNP
rs1428894253 3432 dbSNP
rs549531405 3448 dbSNP
rs754416240 3449 dbSNP
rs371346059 3450 dbSNP
rs938352612 3451 dbSNP
rs1203875575 3455 dbSNP
rs1052669999 3457 dbSNP
rs1218025961 3468 dbSNP
rs1281393460 3476 dbSNP
rs1349173896 3477 dbSNP
rs1252769737 3482 dbSNP
rs1272849597 3487 dbSNP
rs1484198577 3491 dbSNP
rs1207739031 3502 dbSNP
rs1246252924 3507 dbSNP
rs563775847 3508 dbSNP
rs551903898 3514 dbSNP
rs1263565673 3533 dbSNP
rs1192941697 3536 dbSNP
rs1395625044 3540 dbSNP
rs1225216487 3547 dbSNP
rs1166550561 3548 dbSNP
rs1348611758 3549 dbSNP
rs1041749448 3550 dbSNP
rs1438022004 3551 dbSNP
rs947174478 3553 dbSNP
rs1040529577 3554 dbSNP
rs1228307260 3555 dbSNP
rs1295940740 3558 dbSNP
rs943171686 3562 dbSNP
rs910284282 3573 dbSNP
rs914266345 3574 dbSNP
rs1048913341 3579 dbSNP
rs930458290 3580 dbSNP
rs1300058974 3583 dbSNP
rs919191709 3587 dbSNP
rs971929913 3594 dbSNP
rs1186568842 3604 dbSNP
rs1391822811 3605 dbSNP
rs960705809 3607 dbSNP
rs184061244 3608 dbSNP
rs1406678512 3612 dbSNP
rs1326075124 3622 dbSNP
rs1387261563 3631 dbSNP
rs1435075862 3634 dbSNP
rs1319096374 3640 dbSNP
rs1367909287 3644 dbSNP
rs1228629792 3649 dbSNP
rs1283900542 3652 dbSNP
rs1354596650 3653 dbSNP
rs1177625625 3657 dbSNP
rs1230222360 3660 dbSNP
rs953537225 3670 dbSNP
rs1273940503 3671 dbSNP
rs1464473067 3672 dbSNP
rs1206855319 3673 dbSNP
rs923563530 3675 dbSNP
rs1249847136 3676 dbSNP
rs981179556 3685 dbSNP
rs1235521850 3686 dbSNP
rs41267363 3687 dbSNP
rs1165172011 3690 dbSNP
rs1410639942 3692 dbSNP
rs1022790265 3694 dbSNP
rs1410448745 3697 dbSNP
rs1160661381 3699 dbSNP
rs1387781957 3701 dbSNP
rs1180817319 3705 dbSNP
rs1419210691 3707 dbSNP
rs1011102553 3712 dbSNP
rs35769575 3712 dbSNP
rs1333988137 3715 dbSNP
rs1339051005 3721 dbSNP
rs1252057669 3722 dbSNP
rs541304752 3724 dbSNP
rs1031265379 3725 dbSNP
rs527546597 3729 dbSNP
rs1243505635 3741 dbSNP
rs1205378750 3752 dbSNP
rs1006597551 3757 dbSNP
rs561339021 3758 dbSNP
rs1199792118 3767 dbSNP
rs1023718692 3768 dbSNP
rs368908432 3769 dbSNP
rs562082006 3770 dbSNP
rs1007622977 3775 dbSNP
rs1250629943 3778 dbSNP
rs1239702102 3792 dbSNP
rs888892819 3796 dbSNP
rs1048772756 3802 dbSNP
rs1363856348 3804 dbSNP
rs930494166 3805 dbSNP
rs1172473628 3821 dbSNP
rs1400638550 3823 dbSNP
rs1436992043 3825 dbSNP
rs1317523369 3827 dbSNP
rs1309275337 3830 dbSNP
rs919060695 3834 dbSNP
rs374569320 3837 dbSNP
rs1002805638 3839 dbSNP
rs1232497861 3850 dbSNP
rs903077226 3856 dbSNP
rs1036241873 3864 dbSNP
rs1273641450 3870 dbSNP
rs1337767258 3874 dbSNP
rs1206822012 3877 dbSNP
rs1250665332 3880 dbSNP
rs1432122966 3889 dbSNP
rs543162134 3890 dbSNP
rs548368414 3900 dbSNP
rs939324538 3900 dbSNP
rs1484191696 3901 dbSNP
rs762108845 3904 dbSNP
rs980826170 3908 dbSNP
rs969776572 3909 dbSNP
rs3748566 3913 dbSNP
rs915348426 3916 dbSNP
rs989530798 3919 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cccagggAGAGGUUUACAcaga 5'
                 | ||::|:|||    
Target 5' -------UGUCUGAGUGUagcu 3'
 		1 - 15
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000464356.2 | 3UTR | UGUCUGAGUGUAGCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
77 hsa-miR-642b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT082888 ZNF543 zinc finger protein 543 2 2
MIRT108294 BHLHB9 basic helix-loop-helix family member b9 2 2
MIRT348737 ZNF350 zinc finger protein 350 2 2
MIRT381384 EXOG exo/endonuclease G 2 2
MIRT452245 TRAM1 translocation associated membrane protein 1 2 2
MIRT459262 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT468117 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT468402 SETD3 SET domain containing 3 2 2
MIRT469079 RNF168 ring finger protein 168 2 2
MIRT471690 OXR1 oxidation resistance 1 2 2
MIRT477353 EOGT EGF domain specific O-linked N-acetylglucosamine transferase 2 4
MIRT479600 CDC25B cell division cycle 25B 2 2
MIRT482377 AFF4 AF4/FMR2 family member 4 2 4
MIRT484029 LARP4B La ribonucleoprotein domain family member 4B 2 2
MIRT490988 USP22 ubiquitin specific peptidase 22 2 2
MIRT493250 MEF2D myocyte enhancer factor 2D 2 2
MIRT493850 FOXN3 forkhead box N3 2 4
MIRT496086 C17orf85 nuclear cap binding subunit 3 2 2
MIRT500630 TXNIP thioredoxin interacting protein 2 2
MIRT501048 SMEK1 protein phosphatase 4 regulatory subunit 3A 2 2
MIRT525186 ZNF257 zinc finger protein 257 2 4
MIRT534875 QSER1 glutamine and serine rich 1 2 2
MIRT539336 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2 2
MIRT553814 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT555959 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT556289 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT561212 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT567328 HMGB1 high mobility group box 1 2 2
MIRT572385 LRRC6 leucine rich repeat containing 6 2 2
MIRT575529 Map4 microtubule-associated protein 4 2 2
MIRT575684 Map1b microtubule-associated protein 1B 2 2
MIRT576828 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT576953 Pigs phosphatidylinositol glycan anchor biosynthesis, class S 2 3
MIRT608316 SYK spleen associated tyrosine kinase 2 4
MIRT609794 PINX1 PIN2/TERF1 interacting telomerase inhibitor 1 2 2
MIRT609991 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 3
MIRT611381 PNMAL1 paraneoplastic Ma antigen family member 8A 2 4
MIRT613566 YY2 YY2 transcription factor 2 2
MIRT614612 MVK mevalonate kinase 2 2
MIRT615497 MPP2 membrane palmitoylated protein 2 2 2
MIRT616941 OTUD7A OTU deubiquitinase 7A 2 2
MIRT617576 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT618214 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 4
MIRT619885 ABHD17B abhydrolase domain containing 17B 2 2
MIRT620401 MYO1H myosin IH 2 2
MIRT620517 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT622166 SMYD1 SET and MYND domain containing 1 2 2
MIRT623195 MTX3 metaxin 3 2 2
MIRT623440 KIAA0408 KIAA0408 2 4
MIRT624837 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT625706 SHROOM1 shroom family member 1 2 2
MIRT628159 HIP1 huntingtin interacting protein 1 2 2
MIRT629496 SGIP1 SH3 domain GRB2 like endophilin interacting protein 1 2 2
MIRT630240 SOGA3 SOGA family member 3 2 4
MIRT630521 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 4
MIRT635676 COX18 COX18, cytochrome c oxidase assembly factor 2 4
MIRT637820 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT637943 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT640490 EXOC5 exocyst complex component 5 2 2
MIRT642722 ATXN3 ataxin 3 2 2
MIRT649153 LRTM1 leucine rich repeats and transmembrane domains 1 2 2
MIRT649610 ITPKC inositol-trisphosphate 3-kinase C 2 2
MIRT661016 ABCA12 ATP binding cassette subfamily A member 12 2 2
MIRT661055 RPL18A ribosomal protein L18a 2 2
MIRT684041 FOLR1 folate receptor 1 2 2
MIRT691014 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT698908 SPPL2A signal peptide peptidase like 2A 2 2
MIRT700981 PDE4D phosphodiesterase 4D 2 2
MIRT701722 MTMR12 myotubularin related protein 12 2 2
MIRT702724 INSIG1 insulin induced gene 1 2 2
MIRT705057 C5orf15 chromosome 5 open reading frame 15 2 2
MIRT705216 BRWD1 bromodomain and WD repeat domain containing 1 2 2
MIRT706088 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT709458 KRTAP19-1 keratin associated protein 19-1 2 2
MIRT711396 RANBP2 RAN binding protein 2 2 2
MIRT720573 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT725366 MTF2 metal response element binding transcription factor 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-642b-3p Platinum-based doublet chemotherapy sensitive High Lung Adenocarcinoma tissue
hsa-miR-642b-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-642b-3p Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-642b-3p Sunitinib 5329102 NSC750690 approved resistant Low Renal Cell Cancer cell line (ACHN, RCC23)
hsa-miR-642b-3p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (HEYA8)
hsa-miR-642b-3p Fluorouracil 3385 NSC19893 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-642b-3p Platinum 23939 sensitive High High-Grade Serous Ovarian Cancer tissue
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-642b-3p Platinum-based doublet chemotherapy sensitive tissue (lung adenocarcinoma)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-642b-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-642b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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