pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol CASKIN1   
Synonyms ANKS5A
Description CASK interacting protein 1
Transcript NM_020764   
Expression
Putative miRNA Targets on CASKIN1
3'UTR of CASKIN1
(miRNA target sites are highlighted)
>CASKIN1|NM_020764|3'UTR
   1 ACGCCGCCTGGCCGGGCCCTCCCGCGCCGCCCGGGCCCTCCCCGCACACTGACCTATACCTCAGGATGGGCGCGTCTGGG
  81 CGCGGCGCGAGCGGCCGGGCAGGGCCCTGCAGAAGCACAACTCCGGCCCCTGGACCCGGGCCGGGGCGCCCACCGGGGAC
 161 CGCCTGGCCGGGGGCTCCAAGGGCTCTAGGCAGACCCTGCGCCCGCGGGTCCTCCCCACCTGCTGCTCCCCGTGCAATAC
 241 CTGCTGGGCCTCCTGCCCGCGCGGGAGGGGAGGGCGCCCCGGGACCAGGGATGGGGCAGCGCACAGGCCCGGGCCCAGCA
 321 CAGAACTGCCCATCGGGACGCCCGGCCAGCCGCTCGGGCGCAGCACAAGGGACAGGGGACCAAGGTCAGGGCCCCCCTGC
 401 CCCACCGCACCCCCAGAATATAAGCTATCAAGAGTATTAATTTATTGGGAATGAGCTGAGGCGGATTTCCCCAGAGAAAC
 481 AAAAAGGTATAACTTTAACAAATATATATTTAAAGAAAGAAATATTATTGATTCTATAGAAAACCATTTACCAACTGAAA
 561 GGACACGAAGTCTAGCTCCGGACAAAAGCTGTTAGAGGCCCAGGCTGTCTGCCTGCGGTCCTTCCTCCGGCCAGAGTGGA
 641 GGCCCCAGGCTGCTAGCACAGGTGGAAGGCTGGGGCCCGGGGGCGGGTGCTCTGCCGGGGGCTCCTCCGTGCTTCTCTCC
 721 TAAGTTCTCTGCGCCCCAAGAACTCGAGGTTGTGCCTTGCTCTCGGCGGCCGTGTCCTCCTCCTGGCGTGGCTGCGTCCC
 801 AGGGCGCGGGTGGGTTTGGTGAATGTGGGTGTGTCAGCGTGGCAGCCACGTGGAAGCAGGGCATGTAGCAGGCCAGGCCA
 881 CGGGCTTGCAGCTCCTCTGAGGGTGTGCCTGGCCCCCTCTCCAGGGGCTGTGCAGGCAGCCCATCCACCCCAGTGGAGTT
 961 CCCACGGACGCTTCTGCTCATGGTCCAAGGCTGTGTTGTGTGGTCATTCTCGCCCTCCCTTTTCCTCTCTCCTCCTGCCC
1041 CCTCCAAGAAGTACTGACTGGTCTCCTCTATCGTGTTTGCTGATCCACAGTGTTGGGCACAACTTTGACGTTTCTTAAAA
1121 AAAAAATTTAAAAAATGCCGAAAACCAGCGATTGTGGTGTGGGGCGGGTGGAGGCGGCTGGCGGAGGTGGCGTCCCGGCG
1201 TGCAGGGCCCCTTCCTGCTGTCTCACCCCGTGTTTCCCTGCGAGTGGACGTGCCCAGCTGTCCCCCCAGGCCTCTCCTCA
1281 GAGGGCGGCACAGGCTGGGCTCCAGCAGGTGGGCAGGGGAGGTCTGGGCAAGGCGCTGCCGTCGGCTGTCAATAAACAGC
1361 AGGAAAC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' agUGG-UAACGA-UUUCACGUUAa 5'
            ||| : ||||    ||||||| 
Target 5' ccACCTGCTGCTCCCCGTGCAATa 3'
216 - 239 148.00 -14.90
2
miRNA  3' aguGGU-AACGAUUUCACGUUaa 5'
             |||   |||   |||||:  
Target 5' tctCCAGGGGCT---GTGCAGgc 3'
918 - 937 108.00 -11.90
3
miRNA  3' aguGGU--AACGAU----UUCACGUUaa 5'
             |||   |||||    |:||| ||  
Target 5' gccCCAGGCTGCTAGCACAGGTGGAAgg 3'
642 - 669 107.00 -10.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26969223 3 COSMIC
COSN15039465 13 COSMIC
COSN30508388 14 COSMIC
COSN30126409 26 COSMIC
COSN30187612 29 COSMIC
COSN17544394 40 COSMIC
COSN30606517 74 COSMIC
COSM5985940 290 COSMIC
COSM5368128 312 COSMIC
COSM88095 334 COSMIC
COSN31585578 519 COSMIC
COSN22865803 523 COSMIC
COSN5176027 556 COSMIC
COSN31487399 567 COSMIC
COSN32062549 629 COSMIC
COSN24421205 696 COSMIC
COSN31482829 740 COSMIC
COSN1184335 767 COSMIC
COSN25930733 956 COSMIC
COSN20078421 970 COSMIC
COSN31518936 1116 COSMIC
COSN31518709 1140 COSMIC
COSN31596414 1191 COSMIC
COSN31550979 1261 COSMIC
COSN31535748 1344 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs768392558 2 dbSNP
rs1281321271 5 dbSNP
rs1440173660 6 dbSNP
rs977436833 10 dbSNP
rs1335634185 11 dbSNP
rs748967637 12 dbSNP
rs1327199525 13 dbSNP
rs775108304 14 dbSNP
rs1392750810 15 dbSNP
rs769638043 18 dbSNP
rs1404366102 19 dbSNP
rs1408331438 22 dbSNP
rs1178385204 23 dbSNP
rs745736927 24 dbSNP
rs781179875 25 dbSNP
rs1194201633 26 dbSNP
rs770924029 28 dbSNP
rs1271033111 29 dbSNP
rs1220603653 32 dbSNP
rs918872366 33 dbSNP
rs974291616 34 dbSNP
rs747064262 36 dbSNP
rs763372663 38 dbSNP
rs1222103076 40 dbSNP
rs1011641811 42 dbSNP
rs770406077 43 dbSNP
rs773900699 43 dbSNP
rs777883260 43 dbSNP
rs758563745 44 dbSNP
rs1304729504 45 dbSNP
rs752990769 46 dbSNP
rs899928433 51 dbSNP
rs1428490343 53 dbSNP
rs1480491510 55 dbSNP
rs1381042460 56 dbSNP
rs1310086140 59 dbSNP
rs1018416866 64 dbSNP
rs565547183 68 dbSNP
rs1408947688 71 dbSNP
rs1329103695 79 dbSNP
rs1402526089 80 dbSNP
rs997379864 83 dbSNP
rs1460082430 85 dbSNP
rs1345377406 86 dbSNP
rs1224213120 87 dbSNP
rs903011805 88 dbSNP
rs1337519131 92 dbSNP
rs545290440 93 dbSNP
rs1273940068 95 dbSNP
rs1369856675 96 dbSNP
rs1169159554 97 dbSNP
rs531753262 98 dbSNP
rs562249118 99 dbSNP
rs1421171167 100 dbSNP
rs1161989736 102 dbSNP
rs1383191456 103 dbSNP
rs929637482 109 dbSNP
rs898141017 112 dbSNP
rs1038013692 113 dbSNP
rs1187048441 115 dbSNP
rs947772792 117 dbSNP
rs916333083 123 dbSNP
rs1175554624 124 dbSNP
rs1055774859 125 dbSNP
rs542303579 127 dbSNP
rs573333657 128 dbSNP
rs930181784 131 dbSNP
rs1290686799 133 dbSNP
rs1359866052 136 dbSNP
rs1224711704 137 dbSNP
rs923863192 138 dbSNP
rs918713420 143 dbSNP
rs1207958837 147 dbSNP
rs1357679258 152 dbSNP
rs1417300976 158 dbSNP
rs974740552 161 dbSNP
rs1442336418 162 dbSNP
rs1182587802 167 dbSNP
rs978390004 169 dbSNP
rs967972961 171 dbSNP
rs1165560477 172 dbSNP
rs1383378774 174 dbSNP
rs1400225352 175 dbSNP
rs908891310 181 dbSNP
rs985838955 182 dbSNP
rs553465573 184 dbSNP
rs1383308206 186 dbSNP
rs1246683957 188 dbSNP
rs1314500415 191 dbSNP
rs555233425 191 dbSNP
rs1407386729 195 dbSNP
rs540195486 196 dbSNP
rs577874501 197 dbSNP
rs967206306 201 dbSNP
rs772689177 202 dbSNP
rs964123598 204 dbSNP
rs1243352450 205 dbSNP
rs1431579939 206 dbSNP
rs1018807337 217 dbSNP
rs1190003278 220 dbSNP
rs1362574885 228 dbSNP
rs1008380948 231 dbSNP
rs1159637436 232 dbSNP
rs891310296 241 dbSNP
rs1025828305 243 dbSNP
rs1468268376 248 dbSNP
rs994798430 255 dbSNP
rs1194589320 257 dbSNP
rs898759093 258 dbSNP
rs1034665495 259 dbSNP
rs1407042561 260 dbSNP
rs1235967198 263 dbSNP
rs1037961372 268 dbSNP
rs1045792602 270 dbSNP
rs930031120 271 dbSNP
rs1290109402 273 dbSNP
rs897344147 275 dbSNP
rs111717664 276 dbSNP
rs1263407854 280 dbSNP
rs947761483 281 dbSNP
rs894886444 285 dbSNP
rs1160849690 289 dbSNP
rs557989584 292 dbSNP
rs939133350 293 dbSNP
rs923741621 300 dbSNP
rs1379140376 301 dbSNP
rs1173791922 302 dbSNP
rs986109936 304 dbSNP
rs1216978061 306 dbSNP
rs1042233667 311 dbSNP
rs537339483 312 dbSNP
rs1175746631 314 dbSNP
rs915202715 316 dbSNP
rs1243991363 317 dbSNP
rs754211749 320 dbSNP
rs766987817 321 dbSNP
rs990143977 323 dbSNP
rs1391742227 327 dbSNP
rs1236660406 328 dbSNP
rs1309800533 329 dbSNP
rs569069878 329 dbSNP
rs911290443 330 dbSNP
rs987264187 331 dbSNP
rs1313424916 332 dbSNP
rs1215457114 334 dbSNP
rs1364543957 337 dbSNP
rs955494796 339 dbSNP
rs1428212619 342 dbSNP
rs967095030 343 dbSNP
rs761305023 344 dbSNP
rs1436068550 348 dbSNP
rs112027358 349 dbSNP
rs556736415 351 dbSNP
rs762447156 352 dbSNP
rs957423501 353 dbSNP
rs1428832339 356 dbSNP
rs536728811 358 dbSNP
rs994297862 359 dbSNP
rs1034308310 360 dbSNP
rs1258520169 364 dbSNP
rs775224163 366 dbSNP
rs567681873 369 dbSNP
rs547496709 371 dbSNP
rs907219137 373 dbSNP
rs894779770 374 dbSNP
rs1056146117 376 dbSNP
rs1293843689 377 dbSNP
rs1218461293 378 dbSNP
rs1339389887 388 dbSNP
rs1293561013 391 dbSNP
rs1024233517 392 dbSNP
rs1003672488 393 dbSNP
rs994232596 398 dbSNP
rs902264759 399 dbSNP
rs1042613644 400 dbSNP
rs1399449032 403 dbSNP
rs1301811193 406 dbSNP
rs946567602 407 dbSNP
rs915147027 410 dbSNP
rs1489520938 411 dbSNP
rs1462426930 414 dbSNP
rs1356244766 415 dbSNP
rs757476696 415 dbSNP
rs1038990997 416 dbSNP
rs776452835 418 dbSNP
rs770837762 419 dbSNP
rs1190350810 420 dbSNP
rs943283637 421 dbSNP
rs1450264409 422 dbSNP
rs1474383672 423 dbSNP
rs1255556277 425 dbSNP
rs1177894611 432 dbSNP
rs1481894447 433 dbSNP
rs1250150873 434 dbSNP
rs911182101 435 dbSNP
rs1198361771 437 dbSNP
rs1165456556 439 dbSNP
rs1423728693 439 dbSNP
rs986827024 442 dbSNP
rs1273361494 443 dbSNP
rs746974326 444 dbSNP
rs1338402226 445 dbSNP
rs1311341891 449 dbSNP
rs897270569 450 dbSNP
rs772910066 451 dbSNP
rs527653004 452 dbSNP
rs955603820 453 dbSNP
rs571858506 455 dbSNP
rs918717658 458 dbSNP
rs941573327 460 dbSNP
rs972866276 462 dbSNP
rs1166917689 463 dbSNP
rs889950378 467 dbSNP
rs1368164948 469 dbSNP
rs761536655 470 dbSNP
rs1182557088 471 dbSNP
rs1050013762 474 dbSNP
rs1248950760 475 dbSNP
rs962874949 476 dbSNP
rs1017076413 479 dbSNP
rs1281563551 480 dbSNP
rs1469349476 481 dbSNP
rs1241504102 484 dbSNP
rs934197628 485 dbSNP
rs1012424523 486 dbSNP
rs1353788744 487 dbSNP
rs772193884 489 dbSNP
rs1239061892 497 dbSNP
rs1318214565 500 dbSNP
rs959657259 505 dbSNP
rs1158266797 506 dbSNP
rs1412147424 508 dbSNP
rs1035061371 509 dbSNP
rs945679818 510 dbSNP
rs1404855958 513 dbSNP
rs1452378092 516 dbSNP
rs774292421 519 dbSNP
rs1222632480 522 dbSNP
rs1412763434 523 dbSNP
rs913013600 523 dbSNP
rs902255134 525 dbSNP
rs1261532998 529 dbSNP
rs1020746752 530 dbSNP
rs1460985271 530 dbSNP
rs1210570580 531 dbSNP
rs1239044347 533 dbSNP
rs768539963 534 dbSNP
rs552006424 540 dbSNP
rs1038895788 545 dbSNP
rs943244183 546 dbSNP
rs890380760 561 dbSNP
rs138680218 562 dbSNP
rs961353199 564 dbSNP
rs1361305493 565 dbSNP
rs145672192 566 dbSNP
rs1006010923 567 dbSNP
rs1248200217 571 dbSNP
rs918653161 572 dbSNP
rs758817740 578 dbSNP
rs1220097360 582 dbSNP
rs1050326044 586 dbSNP
rs1210218190 595 dbSNP
rs1305576051 598 dbSNP
rs1203511611 600 dbSNP
rs998335582 603 dbSNP
rs972768691 607 dbSNP
rs941462705 611 dbSNP
rs1267641629 612 dbSNP
rs1478053215 613 dbSNP
rs1192615311 617 dbSNP
rs1416887418 624 dbSNP
rs1408603932 628 dbSNP
rs1168279318 629 dbSNP
rs910019515 629 dbSNP
rs749026241 631 dbSNP
rs542338717 642 dbSNP
rs1330636693 643 dbSNP
rs1437225832 644 dbSNP
rs1276866332 645 dbSNP
rs1042654597 649 dbSNP
rs1227414383 652 dbSNP
rs1275159786 657 dbSNP
rs1344037077 657 dbSNP
rs1347030261 658 dbSNP
rs1295385263 660 dbSNP
rs1451696912 665 dbSNP
rs1227318379 668 dbSNP
rs1223075239 669 dbSNP
rs945732094 670 dbSNP
rs912848897 676 dbSNP
rs115022524 679 dbSNP
rs1035314049 683 dbSNP
rs982174161 684 dbSNP
rs182199125 685 dbSNP
rs1020648704 686 dbSNP
rs1010629519 690 dbSNP
rs893566279 692 dbSNP
rs1017409648 696 dbSNP
rs1007432704 697 dbSNP
rs1434730829 701 dbSNP
rs1367160502 702 dbSNP
rs1416310732 702 dbSNP
rs1369232810 703 dbSNP
rs1043186666 705 dbSNP
rs979931341 713 dbSNP
rs890360626 714 dbSNP
rs1281591074 715 dbSNP
rs1051714732 717 dbSNP
rs551665155 719 dbSNP
rs897134980 721 dbSNP
rs1180526163 722 dbSNP
rs528630482 725 dbSNP
rs1182063500 726 dbSNP
rs1471587718 727 dbSNP
rs1473447616 731 dbSNP
rs551483651 731 dbSNP
rs539856895 732 dbSNP
rs577518738 733 dbSNP
rs1456757109 734 dbSNP
rs1321496357 737 dbSNP
rs1391053892 738 dbSNP
rs910011124 738 dbSNP
rs990942750 740 dbSNP
rs1333194293 743 dbSNP
rs938223208 750 dbSNP
rs865875492 760 dbSNP
rs1272300288 761 dbSNP
rs928189919 762 dbSNP
rs954293535 765 dbSNP
rs565958781 768 dbSNP
rs1028398353 770 dbSNP
rs998387852 771 dbSNP
rs1342551230 772 dbSNP
rs901338127 774 dbSNP
rs1443326748 775 dbSNP
rs1190284138 776 dbSNP
rs1276488631 782 dbSNP
rs1042663106 787 dbSNP
rs982361026 788 dbSNP
rs1414480070 789 dbSNP
rs967376579 790 dbSNP
rs1020596149 795 dbSNP
rs1285067566 796 dbSNP
rs891471879 799 dbSNP
rs989146956 803 dbSNP
rs1450229407 804 dbSNP
rs1054508216 805 dbSNP
rs564269694 806 dbSNP
rs957771225 807 dbSNP
rs868582376 808 dbSNP
rs1256205033 810 dbSNP
rs1372987813 813 dbSNP
rs544507949 815 dbSNP
rs1007791138 824 dbSNP
rs954591235 825 dbSNP
rs949927513 829 dbSNP
rs1254150867 830 dbSNP
rs1030593388 831 dbSNP
rs917042380 834 dbSNP
rs993395625 838 dbSNP
rs1378373532 839 dbSNP
rs1467417946 841 dbSNP
rs575544982 843 dbSNP
rs1430403815 845 dbSNP
rs1249010073 849 dbSNP
rs909781831 850 dbSNP
rs1036993616 851 dbSNP
rs1301583869 852 dbSNP
rs1005545092 856 dbSNP
rs1235902215 861 dbSNP
rs1295933807 864 dbSNP
rs1341887628 869 dbSNP
rs954062631 870 dbSNP
rs1487558571 872 dbSNP
rs1268337208 873 dbSNP
rs888519651 874 dbSNP
rs1483326050 876 dbSNP
rs1435192300 879 dbSNP
rs555579831 881 dbSNP
rs1055241257 882 dbSNP
rs1170440666 885 dbSNP
rs1219094121 885 dbSNP
rs1456975303 891 dbSNP
rs965541666 894 dbSNP
rs1392239341 899 dbSNP
rs747263513 899 dbSNP
rs928124017 902 dbSNP
rs1296371971 907 dbSNP
rs151281479 913 dbSNP
rs945569915 914 dbSNP
rs574068108 915 dbSNP
rs1320905033 916 dbSNP
rs777987406 917 dbSNP
rs1266182974 920 dbSNP
rs758707042 925 dbSNP
rs989138669 931 dbSNP
rs1247595182 947 dbSNP
rs957719621 948 dbSNP
rs558063421 956 dbSNP
rs533947241 961 dbSNP
rs1229161035 965 dbSNP
rs111428398 966 dbSNP
rs757648138 969 dbSNP
rs954622955 974 dbSNP
rs1436119054 976 dbSNP
rs1388863021 977 dbSNP
rs1030125883 981 dbSNP
rs993777798 984 dbSNP
rs1323040703 985 dbSNP
rs1377427654 988 dbSNP
rs1396002177 1000 dbSNP
rs961930711 1005 dbSNP
rs1016166343 1009 dbSNP
rs939856036 1011 dbSNP
rs549046396 1012 dbSNP
rs1323749623 1014 dbSNP
rs1235588291 1021 dbSNP
rs1005492525 1024 dbSNP
rs984052222 1024 dbSNP
rs1462674862 1031 dbSNP
rs1258122542 1032 dbSNP
rs1471341382 1032 dbSNP
rs551689675 1035 dbSNP
rs1157684998 1037 dbSNP
rs888425545 1037 dbSNP
rs779599401 1038 dbSNP
rs755587481 1039 dbSNP
rs1002257609 1041 dbSNP
rs932646276 1043 dbSNP
rs1465813264 1048 dbSNP
rs1303967595 1054 dbSNP
rs921229778 1055 dbSNP
rs754379753 1056 dbSNP
rs538125663 1058 dbSNP
rs965427476 1062 dbSNP
rs1046553938 1065 dbSNP
rs765869428 1072 dbSNP
rs914143251 1073 dbSNP
rs1181360825 1074 dbSNP
rs1054063252 1087 dbSNP
rs1251960820 1089 dbSNP
rs1215373303 1090 dbSNP
rs936925223 1091 dbSNP
rs1189121786 1095 dbSNP
rs958225019 1098 dbSNP
rs1414268536 1099 dbSNP
rs1177171042 1106 dbSNP
rs1033048267 1109 dbSNP
rs1428454791 1110 dbSNP
rs760163393 1112 dbSNP
rs905544975 1114 dbSNP
rs1463707423 1117 dbSNP
rs374752828 1122 dbSNP
rs1273328596 1126 dbSNP
rs1013978083 1127 dbSNP
rs1367088855 1127 dbSNP
rs910186896 1127 dbSNP
rs1339768600 1129 dbSNP
rs569177877 1130 dbSNP
rs1229015098 1134 dbSNP
rs1036774548 1136 dbSNP
rs1218659996 1136 dbSNP
rs1483768963 1136 dbSNP
rs1318818639 1138 dbSNP
rs954483137 1139 dbSNP
rs1299768748 1140 dbSNP
rs1192569077 1141 dbSNP
rs923050277 1149 dbSNP
rs971912349 1150 dbSNP
rs1448016289 1157 dbSNP
rs767147970 1165 dbSNP
rs549179412 1166 dbSNP
rs1411735636 1168 dbSNP
rs796496208 1171 dbSNP
rs958621662 1175 dbSNP
rs1033644378 1176 dbSNP
rs1328147438 1177 dbSNP
rs529447044 1182 dbSNP
rs35199162 1183 dbSNP
rs1298253705 1184 dbSNP
rs546671720 1186 dbSNP
rs1009887658 1188 dbSNP
rs1457252026 1188 dbSNP
rs1226524208 1189 dbSNP
rs532829768 1191 dbSNP
rs1009719478 1192 dbSNP
rs1223376705 1193 dbSNP
rs1245763208 1194 dbSNP
rs1463845394 1196 dbSNP
rs564093492 1197 dbSNP
rs1053967493 1200 dbSNP
rs1195248771 1205 dbSNP
rs752710140 1207 dbSNP
rs774171703 1229 dbSNP
rs889405425 1230 dbSNP
rs1050088118 1237 dbSNP
rs1405978695 1240 dbSNP
rs544546595 1241 dbSNP
rs1025164485 1242 dbSNP
rs1013909659 1244 dbSNP
rs1434115300 1249 dbSNP
rs959696883 1250 dbSNP
rs1445789803 1253 dbSNP
rs923028948 1254 dbSNP
rs376350214 1259 dbSNP
rs1254306814 1261 dbSNP
rs575632771 1262 dbSNP
rs796867728 1267 dbSNP
rs561930898 1268 dbSNP
rs996661613 1271 dbSNP
rs1364935890 1277 dbSNP
rs984589322 1279 dbSNP
rs1186079398 1283 dbSNP
rs762936907 1286 dbSNP
rs1034712703 1287 dbSNP
rs980782152 1295 dbSNP
rs1409836960 1296 dbSNP
rs1363702063 1298 dbSNP
rs971158947 1307 dbSNP
rs913866731 1309 dbSNP
rs1465156345 1333 dbSNP
rs1024992960 1334 dbSNP
rs142263447 1335 dbSNP
rs572949267 1338 dbSNP
rs775494645 1340 dbSNP
rs554023423 1341 dbSNP
rs1285978365 1342 dbSNP
rs1389344099 1343 dbSNP
rs190417881 1344 dbSNP
rs918207902 1345 dbSNP
rs770922152 1350 dbSNP
rs992331277 1353 dbSNP
rs1278555793 1354 dbSNP
rs1430488279 1357 dbSNP
rs1254416957 1358 dbSNP
rs1190694851 1359 dbSNP
rs889363455 1363 dbSNP
rs959706707 1368 dbSNP
rs1181341290 1369 dbSNP
rs1051143046 1371 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' agugguaacgauuucACGuuaa 5'
                         |||    
Target 5' cggguccuccccaccUGCugcu 3'
5 - 26
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000343516.6 | 3UTR | CCCGCGGGUCCUCCCCACCUGCUGCUCCCCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla -0.676 5.6e-3 -0.603 1.5e-2 13 Click to see details
GSE32688 Pancreatic cancer -0.341 2.8e-2 -0.443 5.6e-3 32 Click to see details
GSE27834 Pluripotent stem cells 0.418 5.4e-2 0.394 6.6e-2 16 Click to see details
GSE19350 CNS germ cell tumors -0.471 6.1e-2 -0.287 1.8e-1 12 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.289 8.1e-2 -0.194 1.8e-1 25 Click to see details
GSE28544 Breast cancer 0.271 1.0e-1 0.321 6.3e-2 24 Click to see details
GSE26953 Aortic valvular endothelial cells -0.205 1.7e-1 -0.359 4.2e-2 24 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.184 2.2e-1 0.141 2.8e-1 20 Click to see details
GSE21849 B cell lymphoma 0.138 2.4e-1 0.136 2.4e-1 29 Click to see details
GSE17306 Multiple myeloma -0.098 2.5e-1 0.320 1.2e-2 49 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.327 3.0e-1 0.000 5.0e-1 5 Click to see details
GSE14794 Lymphoblastoid cells 0.044 3.4e-1 0.006 4.8e-1 90 Click to see details
GSE21687 Ependynoma primary tumors -0.041 3.7e-1 0.011 4.7e-1 64 Click to see details
GSE38226 Liver fibrosis -0.007 4.9e-1 0.006 4.9e-1 21 Click to see details
GSE38226 Liver fibrosis -0.007 4.9e-1 0.006 4.9e-1 21 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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