miRTarBase - #MIRT494763


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pre-miRNA Information
pre-miRNA hsa-mir-2681   
Genomic Coordinates chr13: 101967642 - 101967746
Description Homo sapiens miR-2681 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2681-5p
Sequence 22| GUUUUACCACCUCCAGGAGACU |43
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 6 13 - 101967720 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1263364397 4 dbSNP
rs1184634146 7 dbSNP
rs1464264801 10 dbSNP
rs1173765682 11 dbSNP
rs1263470724 12 dbSNP
rs906180025 15 dbSNP
rs935390707 20 dbSNP
rs1045157564 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol AP1G1   
Synonyms ADTG, CLAPG1
Description adaptor related protein complex 1 gamma 1 subunit
Transcript NM_001030007   
Other Transcripts NM_001128   
Expression
Putative miRNA Targets on AP1G1
3'UTR of AP1G1
(miRNA target sites are highlighted)		 
>AP1G1|NM_001030007|3'UTR
   1 GGGTTTGGCACCATTCTCATTCTTTATCCCACTCAATCAAAGGAACTCTGGGAAGGAGGTTGTGATTGCTGGCAAGTCCC
  81 CCCCAACTGTACCACGGGCATGAGGAGCTGAAGAGAACTGCTGAGGAGGATTTTCCTAAAGTTACTGCTGACCTTGAAGC
 161 ATTGTTAAAGACTAATGTCCTCTCCTCCACTGTTGAGGCTGGCTGCTTCTGGAGGCTACTTTGCACTCTTCCTCTTCTCC
 241 TTTTTCCGCACTTCTCCACCCCTCCCACATTTACAGCCAGAATCAACATTCCCTGGGCCCCTGAGGAAATAAGCAGCTGG
 321 TCTGGAGGAGAGGACTGCAATCCATGGCGAAAAAACACTCACTTTGTCTCTGCAGCAAAGAGTTGCCCCTTCTTTCTACT
 401 GTTGTTTCTCTGTGGACTGGGCAAGGTGGGGTATTTATTCCTCACTAGCTGGGTTACCATCTTCAGGCACTTTTAACATC
 481 TGGCATTCGGAATGGAAATGTAATAATGGACATTAGGGAGCCCTGCCTTTTTCTACTGGTTCCCCCAATGTTTGAAAGAG
 561 GCATTAGGCTCCTGGTAGCCTTTTCTGTGCATTGCTGTATACACACAGACACACACATGTATGTTTGTTACCAAGAACTG
 641 GTCAGACCTTGCGAGTTTATTTGTAAACACTGGACAGATGGAGTTAAAAAGAGCTTTTGTTGAGATTTGGCATGAAGGAT
 721 ATGGTGCTCTATTTGTAATAGAAACTTCCAAGGCTCTTCCAGCTCCCCTTTCTCGCCATTCTTTAGCTGTAGTCATGAAT
 801 AGTCTCCATGATTTTCAAAATTGATTCCCTTTAAAGTGCAAAATGGTCACCTTCTAAAAGATATATTCATAGTTATTAAT
 881 GACCCTATTCCCACCACAAATTTTAAAGTGCTCCTAAGCCCATAACTTGCCTGTTTGAACTATGGTAATGGGTGGAAGAG
 961 GAGTTCACCAGTTTCAAAGATCAGACTCTGTATCAAAAGTACCTTTGCCCTTAGGAAGAGTGAGTATTGGAGTCATCTTA
1041 TCTATTACTCCAAACCTCCCTTTTTATTTCTTGAGCCTGGCTTGGACCTTGGCATTCCGTTTGAATTCCTTCTAACTGGA
1121 ACATTTGTGTTGTATCTGTAACACTGGCACTGAAATAAAGACCACACGGTTAAAGAAATCTTTCCATATTGTACTTTATG
1201 GTGTTGGAGTGAAGCCTTGTAGCTTCCATACCCCTATGTCAGAGGAGGTCTTACGGACACCATAGGGTAGGAATAGCCTT
1281 TCCTCAGTCTGAGAAATTGGTCTCTTTTAAAAGACGAATCTCATGAATATTCACATCAAAGACTTGAGCTTTTTAAACTA
1361 GTGAGAGTGCCAAGTGCTTTTTAGAAAGGACCCATATGTTATCAAACTTTGAAATTGAGTTGCTGGAATGAAGTAGAGGT
1441 GACTCTCTCTGTGGTACACATTGAATGTACTATGTATGTTCAAGTATTCAGGCGCCATGTCTTATATACTGAAGAAAGAA
1521 AAAGTGAGGCCCACCTTGCTCTTACAATGTTTGCAATTGTTACTGTATTGAATACAGTATAATGACTACTATGGCTTCAA
1601 TCTTAAACCTGGAAACAAATATCCCTTTTTTTCCCCTTCATTTCACCAAGCCTTTACTTAAAATCTTCAGTGTCTTGTCA
1681 AATCTAGCTCTGTATCAGATGCTGGAATATTCCTAACATTTGACAAACTGGAGTTGAACTAAAGGCTCCACGGGAAAGTT
1761 TCTGGTCTTACTAGTGTGTATGAGCAAGATCTGCTAAAACTTACTCCACTGGGTAAATGGTTGACTGAGTCAAGAACAGG
1841 ATAATATCTCCTGCATAGTTTTCAGTAATGTAAGTGTGGACTAGTGCATATTTCAGACAACTGCTCTGCCTGTGCAATGA
1921 AAAATAGCCTTTAAGGGTTTCTTTGCAGACTGATTTCATTGGATGGATACTTAATGCTGTGAAACATGATAGGATTAACA
2001 TAATGTTGGTGGATTTCTTGAATAGAATTTGTCTTAACATTCCTCTTTGTGTAGAGGCTTTATTTTCTCTCTTATATTTG
2081 TAGCTAACCAGCTCAGGTTTTTTTATTTGAACTGGGTTGAATCTCTGAAGAAATCTGTTCAAGACCATGCTATAAGACAC
2161 TGTCAGCTAATGGAGCTGGGAAGGGTCTACTCTGCTGACAGAGCATTTCCTTGGGTGATCATAGTTTCGAGGTAGAGTTT
2241 ATGATCATTCATAGCTTTGTCTAGAAGGAGTAAAATATCATGGCCTTAACACAAAGGGTGCTGCGTAGAATATGAATTGA
2321 TTTTGGAATCAGAACACAAGCACCATACTGAAGGACTAGCAGCCAAATAACTGCCTAGGATACTGATGGTTGTGAAGACT
2401 GTTTCAAATGATTGGATCTTTGAAAGCTTCAGCGTGCCTTAGTTTCTAGGATCAGAATTAGTTTTCCTCTCACTTGGCCT
2481 TGCAGCTAAATGGAGAAATGTTTCAATTTCTTTGAATACTTGCACATTTCAATAATTCCTTTCCCGAGTATAACCACTCA
2561 AGGGGGAGCAAATTTGGATGGATTTACGACTTCACAGGCATTGTGAGGAAAGAGCATTTTCCAAGGCTGTTTTGATAACC
2641 CTGGGGTGATAAGCAGTGAGCCCTCACACACTTACTTTGACAATTTCACATGCACTTGTACTTCATTATTTCCCTCTTCA
2721 AGAGTCGTTTCTATTCTAGTTTCTGCCCCATCCCGGGGAATCCTAAAGGAGAATTAATTCATCTAAGTAATCTCAAAAAA
2801 CTGTAGGAAGGGTGCTCTCCCTGAGAAGCTTCTCCCACAGTGCTTTGGTGCTGTTACCTTGAGGTGGTTTGGACAGTCAC
2881 GGAAGTTTTAGGCTGTGCATAGTGATCATCTGTTAATTTTAAGGTCTTTATCATTTAAAGAAACATTCCTCAGTGTAACA
2961 TTTGGGAGGGGATTCTTTCCTCTTGCTAGTTTAAAGGTGTGATTTGTACTCCTTGTTTGTCCCATTCATATATGAAAATA
3041 GACTTTTAAAACTGTCCAACACTAATGGTTTATATAACATGCTTCCCATTTTTTTTATGTCGTAGAAATTGGAAGTTAGG
3121 GAGTACTGCTTTCAAGGTTCAACTTCATTATCTTCTGCATTGGAAAATATTTGGGCCATGAGAACTAGGGGAAAGGAGTT
3201 TGAATGTGTCTATTTTTTTCTAGTGAATGTATTTTAACCACAGTGTCCTAAACTGAGAAAACTAGAGAGGAAAAAGTGGG
3281 TGTTCATGAACTTTGTAGTTGGGAGAGTGGTTTTACATGTCTGTGTATTCATGACTTTGGGAGTGGGTAGGATCATTGGA
3361 GAGAGAATTGCACAGAAAGTCCTGAAGTTTAAAACACTTTTGACCAGCTTTGGCTCGGGAGAGTGGGGCTGCTTGTAGAA
3441 CTGGAAGTGAATAACTTTTTCAAGCAATATCAGTGAGTGGGTCCCATCGACAGGGTTCCAGGACCTGGAACACTTTAACA
3521 GAAGGAAATGCCGAAGCAGCTTGCACAGTTGCTTTACAGACTTCCAAGAGGCTGATTCTGGCTTCAAGATGGAGCCTTGG
3601 AGTTGGTTTTTTTTTTTTTTTTTTTCTTCCCTCAAAGAACCTGCGGTTGCGCTTTGTGTGTTTTGTTTTTGTTTTCCATT
3681 TGGGGGCCCCATGGGAAAGAGCTTCTGAACTCTTTCCTTTATGAACTCCCACTGTGTTCCTATAAAGGCCCTTTTCTTTC
3761 TTAGTGTTGTAAGTTACATTTTCATTATGCCCCATCACATCTTCTTTACTGTAAAAATATTAAAAAGCTGTTTCCAAGTG
3841 GGACAGCTAATGAAGCTCTAATTATTGCAGACATATTTTTGAGATGTAAAAAAAAAAATTTAAAGTTAAATGATAAGTCT
3921 TAGAGGCGAGTGAGGAATAAAATGGATGTAAACATTTACATGGGATGCATTAGAATTCTGCTGTGTGTACTGTCTTTTGG
4001 TTGAAACAAATTATGAACAGTGACTAATAATAAAAAGTCAATACCCAATGATTTAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucaGAGGACCUCCACCAUUUUg 5'
             ||:: ||||  ||||::| 
Target 5' tgaCTTTGGGAGTGGGTAGGAt 3'
 3332 - 3353 131.00 -16.10
2 
miRNA  3' ucAGAGGACCUCCACCAUUUUg 5'
            |: :|| || |  |||||| 
Target 5' ctTTGTCTAGAAGGAGTAAAAt 3'
 2255 - 2276 128.00 -8.70
3 
miRNA  3' ucaGAGGACCUCCACCAUUUug 5'
             ||||   |   ||||||  
Target 5' ttaCTCC---ACTGGGTAAAtg 3'
 1801 - 1819 124.00 -9.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30162197 7 COSMIC
COSN18747601 77 COSMIC
COSN30493327 124 COSMIC
COSN26552369 160 COSMIC
COSN26119511 175 COSMIC
COSN30104640 197 COSMIC
COSN30173517 645 COSMIC
COSN30105138 1042 COSMIC
COSN31520315 1068 COSMIC
COSN22469555 1098 COSMIC
COSN20334854 1099 COSMIC
COSN31565998 1175 COSMIC
COSN31532929 1276 COSMIC
COSN31483851 1289 COSMIC
COSN30166926 1384 COSMIC
COSN28651194 1496 COSMIC
COSN20113075 1518 COSMIC
COSN28695793 1545 COSMIC
COSN6093298 1603 COSMIC
COSN31482044 1696 COSMIC
COSN26639708 2043 COSMIC
COSN20766804 2192 COSMIC
COSN26557863 2301 COSMIC
COSN31484596 2530 COSMIC
COSN31486901 2550 COSMIC
COSN16021540 2735 COSMIC
COSN20093159 2752 COSMIC
COSN23849987 2758 COSMIC
COSN31568612 2771 COSMIC
COSN8236861 2859 COSMIC
COSN30173261 2932 COSMIC
COSN30173182 2951 COSMIC
COSN26635087 2959 COSMIC
COSN31513073 2968 COSMIC
COSN28671430 3182 COSMIC
COSN30167025 3419 COSMIC
COSN14449747 3421 COSMIC
COSN26465306 3508 COSMIC
COSN31542866 3510 COSMIC
COSN26574214 3519 COSMIC
COSN32056995 3532 COSMIC
COSN28775375 3606 COSMIC
COSN31594533 3610 COSMIC
COSN17427632 3626 COSMIC
COSN30540647 3731 COSMIC
COSN20093158 3773 COSMIC
COSN20113071 3887 COSMIC
COSN31548069 4048 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs761467938 1 dbSNP
rs773944366 5 dbSNP
rs768203007 11 dbSNP
rs1056905240 12 dbSNP
rs1374193856 23 dbSNP
rs768442011 26 dbSNP
rs200448545 27 dbSNP
rs1467116732 28 dbSNP
rs1446487739 36 dbSNP
rs1361206875 47 dbSNP
rs1313878831 51 dbSNP
rs1175108649 76 dbSNP
rs113530943 78 dbSNP
rs902882345 82 dbSNP
rs1042741484 83 dbSNP
rs1191311045 84 dbSNP
rs1426156228 85 dbSNP
rs1008357388 86 dbSNP
rs530311104 88 dbSNP
rs563023607 92 dbSNP
rs1463520246 93 dbSNP
rs544927536 95 dbSNP
rs1390907721 96 dbSNP
rs1381233769 99 dbSNP
rs932301208 100 dbSNP
rs919620204 105 dbSNP
rs1038281123 106 dbSNP
rs1218984120 107 dbSNP
rs1292505236 121 dbSNP
rs755459557 123 dbSNP
rs939970704 129 dbSNP
rs1332576978 131 dbSNP
rs577575699 138 dbSNP
rs1224346987 143 dbSNP
rs752152814 146 dbSNP
rs1266040720 153 dbSNP
rs992369333 172 dbSNP
rs1277834623 178 dbSNP
rs960544621 180 dbSNP
rs1488762053 182 dbSNP
rs1238992400 183 dbSNP
rs912705603 187 dbSNP
rs565304077 189 dbSNP
rs184500521 199 dbSNP
rs1426067902 230 dbSNP
rs573292602 231 dbSNP
rs1333800094 232 dbSNP
rs980208886 237 dbSNP
rs970034216 238 dbSNP
rs1022079457 247 dbSNP
rs555039498 248 dbSNP
rs974048079 249 dbSNP
rs1335751930 251 dbSNP
rs535337952 257 dbSNP
rs1312048326 258 dbSNP
rs990414569 267 dbSNP
rs956450644 268 dbSNP
rs1426691286 269 dbSNP
rs1313377293 273 dbSNP
rs759024708 273 dbSNP
rs1316373489 277 dbSNP
rs574297350 279 dbSNP
rs1236931916 280 dbSNP
rs1156263453 286 dbSNP
rs1488731910 288 dbSNP
rs780246974 294 dbSNP
rs758894758 297 dbSNP
rs1484448498 299 dbSNP
rs1364250731 302 dbSNP
rs750620151 307 dbSNP
rs1459862223 309 dbSNP
rs138023626 310 dbSNP
rs1381700637 317 dbSNP
rs1419863093 318 dbSNP
rs1172640948 322 dbSNP
rs1046350 327 dbSNP
rs1357168352 328 dbSNP
rs1204606460 330 dbSNP
rs1449994971 332 dbSNP
rs1303255594 334 dbSNP
rs1372495284 337 dbSNP
rs1389657556 338 dbSNP
rs761947285 339 dbSNP
rs998654102 340 dbSNP
rs1444297004 343 dbSNP
rs996583709 344 dbSNP
rs1233769313 345 dbSNP
rs898155602 348 dbSNP
rs1314267388 349 dbSNP
rs1282290542 350 dbSNP
rs1482548248 356 dbSNP
rs1038402484 359 dbSNP
rs1479942113 376 dbSNP
rs1223229065 377 dbSNP
rs1239413794 378 dbSNP
rs939711967 382 dbSNP
rs886998090 387 dbSNP
rs1192577556 407 dbSNP
rs150332902 408 dbSNP
rs1244420784 412 dbSNP
rs1415867853 416 dbSNP
rs1353773299 429 dbSNP
rs939151596 431 dbSNP
rs1333298074 433 dbSNP
rs926472785 443 dbSNP
rs980174882 453 dbSNP
rs1440299501 457 dbSNP
rs1301390821 458 dbSNP
rs948822817 459 dbSNP
rs1369987611 466 dbSNP
rs1220101859 470 dbSNP
rs914666318 474 dbSNP
rs947047751 488 dbSNP
rs573996962 489 dbSNP
rs1259308947 503 dbSNP
rs551919681 506 dbSNP
rs1468461030 516 dbSNP
rs956082874 521 dbSNP
rs865901266 522 dbSNP
rs1315626699 535 dbSNP
rs1399669375 536 dbSNP
rs1385041002 545 dbSNP
rs1160423307 547 dbSNP
rs533770773 548 dbSNP
rs1040005195 558 dbSNP
rs987041904 560 dbSNP
rs1418451697 564 dbSNP
rs566490962 568 dbSNP
rs944275642 587 dbSNP
rs1183932006 589 dbSNP
rs1172680172 590 dbSNP
rs548269158 591 dbSNP
rs955528727 599 dbSNP
rs1215317096 602 dbSNP
rs761768149 616 dbSNP
rs1028485409 617 dbSNP
rs748372188 619 dbSNP
rs1351692395 627 dbSNP
rs370120550 633 dbSNP
rs529770756 643 dbSNP
rs930121925 649 dbSNP
rs192158106 652 dbSNP
rs1338852573 653 dbSNP
rs1220819872 655 dbSNP
rs1279291565 663 dbSNP
rs996971194 671 dbSNP
rs1334749544 673 dbSNP
rs141188209 683 dbSNP
rs974100677 685 dbSNP
rs1016699013 693 dbSNP
rs1241190151 699 dbSNP
rs11539981 707 dbSNP
rs532887181 708 dbSNP
rs1487126847 713 dbSNP
rs1004264385 720 dbSNP
rs969379914 726 dbSNP
rs1474802532 728 dbSNP
rs764283446 729 dbSNP
rs1220966751 731 dbSNP
rs565564516 738 dbSNP
rs916566791 742 dbSNP
rs1056385159 753 dbSNP
rs1046351 754 dbSNP
rs113301251 759 dbSNP
rs1035573265 760 dbSNP
rs1355225245 764 dbSNP
rs905024954 766 dbSNP
rs1243175713 768 dbSNP
rs553853144 774 dbSNP
rs540311061 775 dbSNP
rs1268114495 780 dbSNP
rs1284747631 783 dbSNP
rs1351048957 786 dbSNP
rs760500038 788 dbSNP
rs1218348210 795 dbSNP
rs1021401492 800 dbSNP
rs914616144 801 dbSNP
rs899531137 805 dbSNP
rs1039380916 811 dbSNP
rs990273921 821 dbSNP
rs1378616056 825 dbSNP
rs1421677380 827 dbSNP
rs775566059 832 dbSNP
rs771839514 833 dbSNP
rs1394686071 839 dbSNP
rs759337452 841 dbSNP
rs924648612 845 dbSNP
rs1442189237 846 dbSNP
rs987007617 850 dbSNP
rs1374035015 852 dbSNP
rs1241806700 860 dbSNP
rs1047276191 869 dbSNP
rs1343908805 872 dbSNP
rs1198495412 873 dbSNP
rs564028215 882 dbSNP
rs773926715 887 dbSNP
rs1442933511 888 dbSNP
rs920071582 893 dbSNP
rs1236368439 897 dbSNP
rs1038445414 905 dbSNP
rs1179445080 913 dbSNP
rs1265465874 921 dbSNP
rs1394670322 922 dbSNP
rs148194062 925 dbSNP
rs1174662629 926 dbSNP
rs561081950 926 dbSNP
rs916619083 930 dbSNP
rs1270309545 942 dbSNP
rs1329937858 944 dbSNP
rs1373961877 954 dbSNP
rs1448315290 957 dbSNP
rs992570911 958 dbSNP
rs1330137754 960 dbSNP
rs775483024 963 dbSNP
rs1276323136 982 dbSNP
rs1345466633 983 dbSNP
rs1306161113 986 dbSNP
rs1197875268 990 dbSNP
rs1256110695 992 dbSNP
rs543116515 1002 dbSNP
rs1199325859 1004 dbSNP
rs1266832951 1008 dbSNP
rs1431650589 1010 dbSNP
rs1201300395 1013 dbSNP
rs977340389 1018 dbSNP
rs1378526127 1020 dbSNP
rs575301003 1029 dbSNP
rs1318124716 1031 dbSNP
rs1169037804 1038 dbSNP
rs754919461 1041 dbSNP
rs1279549992 1044 dbSNP
rs1331435870 1053 dbSNP
rs1021457122 1057 dbSNP
rs963788860 1058 dbSNP
rs1331428330 1059 dbSNP
rs1217751628 1070 dbSNP
rs1402496435 1071 dbSNP
rs1344311496 1097 dbSNP
rs1294111917 1098 dbSNP
rs545414392 1099 dbSNP
rs1487560278 1105 dbSNP
rs1438484100 1112 dbSNP
rs748779121 1113 dbSNP
rs1352598139 1118 dbSNP
rs1268277877 1119 dbSNP
rs114654895 1121 dbSNP
rs1017986681 1122 dbSNP
rs373630086 1123 dbSNP
rs1169424159 1126 dbSNP
rs890769549 1136 dbSNP
rs534305902 1146 dbSNP
rs1047781713 1153 dbSNP
rs1367327148 1158 dbSNP
rs1455957672 1167 dbSNP
rs537633912 1168 dbSNP
rs753776695 1178 dbSNP
rs187863231 1180 dbSNP
rs1399073417 1183 dbSNP
rs898701714 1187 dbSNP
rs1342146268 1189 dbSNP
rs1174529399 1191 dbSNP
rs558809808 1197 dbSNP
rs1319897871 1198 dbSNP
rs1480188759 1198 dbSNP
rs766191499 1201 dbSNP
rs1247057826 1203 dbSNP
rs1266176209 1205 dbSNP
rs1038499927 1228 dbSNP
rs948183991 1230 dbSNP
rs533796861 1237 dbSNP
rs1269655164 1242 dbSNP
rs1426123487 1244 dbSNP
rs879543247 1248 dbSNP
rs369411172 1254 dbSNP
rs1056521450 1262 dbSNP
rs1479915439 1263 dbSNP
rs566470871 1269 dbSNP
rs1420052184 1272 dbSNP
rs1302097908 1276 dbSNP
rs939364949 1277 dbSNP
rs769382797 1281 dbSNP
rs1313448071 1284 dbSNP
rs1376274540 1286 dbSNP
rs76295742 1290 dbSNP
rs1238177883 1300 dbSNP
rs868123832 1307 dbSNP
rs1457948384 1310 dbSNP
rs1288462061 1314 dbSNP
rs1259657458 1326 dbSNP
rs1209823091 1330 dbSNP
rs1354733294 1330 dbSNP
rs571368068 1334 dbSNP
rs1221299207 1348 dbSNP
rs1484522903 1360 dbSNP
rs1182953094 1361 dbSNP
rs1322267441 1364 dbSNP
rs923945988 1365 dbSNP
rs866070664 1371 dbSNP
rs1220895958 1373 dbSNP
rs977768573 1392 dbSNP
rs1419365514 1394 dbSNP
rs1297405153 1399 dbSNP
rs945940855 1402 dbSNP
rs1402191309 1403 dbSNP
rs914448581 1405 dbSNP
rs1444611621 1415 dbSNP
rs755253799 1419 dbSNP
rs1377907353 1424 dbSNP
rs1469459465 1426 dbSNP
rs989988469 1433 dbSNP
rs1314322131 1445 dbSNP
rs1356646085 1447 dbSNP
rs547839061 1451 dbSNP
rs562074669 1451 dbSNP
rs963840342 1451 dbSNP
rs536372577 1454 dbSNP
rs1178272563 1456 dbSNP
rs184945757 1467 dbSNP
rs1239538262 1470 dbSNP
rs576766709 1474 dbSNP
rs145724519 1475 dbSNP
rs1179805175 1476 dbSNP
rs747461597 1477 dbSNP
rs1434716707 1481 dbSNP
rs532745940 1483 dbSNP
rs1464049583 1484 dbSNP
rs1241653155 1491 dbSNP
rs1025300041 1493 dbSNP
rs374864677 1494 dbSNP
rs28530730 1496 dbSNP
rs547275857 1504 dbSNP
rs868781197 1505 dbSNP
rs1256109432 1509 dbSNP
rs1220157547 1513 dbSNP
rs199771699 1524 dbSNP
rs191624070 1528 dbSNP
rs895290818 1529 dbSNP
rs1306284752 1540 dbSNP
rs11539980 1545 dbSNP
rs1220327814 1546 dbSNP
rs1244585753 1547 dbSNP
rs114702688 1548 dbSNP
rs1199862179 1553 dbSNP
rs530945851 1556 dbSNP
rs1476761280 1557 dbSNP
rs549281506 1558 dbSNP
rs1403095877 1562 dbSNP
rs563432621 1568 dbSNP
rs1404871038 1571 dbSNP
rs764078726 1576 dbSNP
rs529531951 1582 dbSNP
rs1304676327 1585 dbSNP
rs1405853448 1589 dbSNP
rs544047451 1591 dbSNP
rs1297903185 1592 dbSNP
rs1338921213 1600 dbSNP
rs1402349990 1619 dbSNP
rs1042391577 1620 dbSNP
rs946662542 1621 dbSNP
rs187478347 1622 dbSNP
rs1227219492 1624 dbSNP
rs1287198136 1626 dbSNP
rs558424563 1628 dbSNP
rs942528831 1632 dbSNP
rs1262127800 1633 dbSNP
rs375474143 1637 dbSNP
rs911040603 1640 dbSNP
rs1195702644 1648 dbSNP
rs986985285 1651 dbSNP
rs1180190091 1652 dbSNP
rs1416060488 1661 dbSNP
rs1442065688 1665 dbSNP
rs1383803631 1671 dbSNP
rs573024372 1684 dbSNP
rs1421877758 1687 dbSNP
rs1422892049 1703 dbSNP
rs1319446373 1706 dbSNP
rs1340378278 1712 dbSNP
rs1446546504 1716 dbSNP
rs1281852598 1718 dbSNP
rs1384380487 1722 dbSNP
rs554580945 1729 dbSNP
rs955147535 1730 dbSNP
rs1183232957 1732 dbSNP
rs1284906422 1742 dbSNP
rs1351104357 1745 dbSNP
rs1484629769 1749 dbSNP
rs1284775387 1750 dbSNP
rs1025775066 1751 dbSNP
rs1239237022 1752 dbSNP
rs752517883 1755 dbSNP
rs1445354076 1756 dbSNP
rs972379913 1764 dbSNP
rs962324427 1769 dbSNP
rs1017156228 1770 dbSNP
rs1159503740 1771 dbSNP
rs767447327 1773 dbSNP
rs1217271076 1778 dbSNP
rs1355712652 1787 dbSNP
rs1336741690 1788 dbSNP
rs372408005 1790 dbSNP
rs1244903321 1793 dbSNP
rs569016182 1802 dbSNP
rs1374196325 1804 dbSNP
rs1240752580 1824 dbSNP
rs1340834813 1829 dbSNP
rs1315190857 1837 dbSNP
rs1344066619 1837 dbSNP
rs1346332815 1838 dbSNP
rs1380718059 1841 dbSNP
rs1361421252 1844 dbSNP
rs759286274 1846 dbSNP
rs1461754895 1848 dbSNP
rs1298836217 1851 dbSNP
rs1035186226 1855 dbSNP
rs1422096050 1857 dbSNP
rs1236499600 1868 dbSNP
rs182787875 1869 dbSNP
rs538691637 1872 dbSNP
rs1004076697 1875 dbSNP
rs1458795698 1879 dbSNP
rs1370531525 1884 dbSNP
rs571821911 1885 dbSNP
rs1430580912 1886 dbSNP
rs1426312089 1889 dbSNP
rs1042464525 1902 dbSNP
rs1397522019 1906 dbSNP
rs1010927390 1910 dbSNP
rs546844990 1911 dbSNP
rs1305205113 1913 dbSNP
rs1489236605 1914 dbSNP
rs528803817 1917 dbSNP
rs1230770068 1928 dbSNP
rs942582131 1937 dbSNP
rs141950851 1938 dbSNP
rs1217936966 1939 dbSNP
rs139395497 1944 dbSNP
rs1341587238 1946 dbSNP
rs1209163551 1957 dbSNP
rs1356841673 1958 dbSNP
rs1266902722 1979 dbSNP
rs1266967277 1998 dbSNP
rs373858987 1999 dbSNP
rs1270057077 2003 dbSNP
rs1477748327 2009 dbSNP
rs1169193901 2015 dbSNP
rs1420786704 2023 dbSNP
rs1225550040 2029 dbSNP
rs1168044791 2035 dbSNP
rs1389555263 2036 dbSNP
rs1384781749 2039 dbSNP
rs1050949486 2042 dbSNP
rs1304657909 2042 dbSNP
rs1399265747 2043 dbSNP
rs530809543 2053 dbSNP
rs563295222 2067 dbSNP
rs1309226571 2069 dbSNP
rs933784247 2071 dbSNP
rs1264997434 2073 dbSNP
rs1354427925 2074 dbSNP
rs146897411 2075 dbSNP
rs1401986747 2086 dbSNP
rs1343712568 2095 dbSNP
rs1488187451 2105 dbSNP
rs918355679 2105 dbSNP
rs770758177 2107 dbSNP
rs749696225 2125 dbSNP
rs3751817 2127 dbSNP
rs1429692726 2132 dbSNP
rs149200383 2135 dbSNP
rs546235794 2136 dbSNP
rs866786192 2141 dbSNP
rs1456006296 2147 dbSNP
rs1460152680 2152 dbSNP
rs1422393639 2153 dbSNP
rs1418831966 2157 dbSNP
rs540028962 2157 dbSNP
rs959648929 2166 dbSNP
rs1035643790 2167 dbSNP
rs769131565 2176 dbSNP
rs747701192 2178 dbSNP
rs1003724273 2180 dbSNP
rs1478556641 2181 dbSNP
rs1426554620 2186 dbSNP
rs573129642 2189 dbSNP
rs1198142234 2203 dbSNP
rs1254801782 2207 dbSNP
rs190958374 2229 dbSNP
rs1184941923 2230 dbSNP
rs780671496 2240 dbSNP
rs1454293250 2241 dbSNP
rs1438757680 2250 dbSNP
rs1156662662 2267 dbSNP
rs1346759937 2271 dbSNP
rs1269239037 2272 dbSNP
rs542694062 2276 dbSNP
rs1302225386 2279 dbSNP
rs1400035180 2281 dbSNP
rs1454628535 2281 dbSNP
rs1337541927 2282 dbSNP
rs1376439396 2285 dbSNP
rs1021068947 2297 dbSNP
rs1457496965 2302 dbSNP
rs116598525 2304 dbSNP
rs74027296 2305 dbSNP
rs746427720 2308 dbSNP
rs1463086652 2336 dbSNP
rs1007933372 2349 dbSNP
rs1274282353 2352 dbSNP
rs1445192002 2366 dbSNP
rs145308652 2367 dbSNP
rs1409835756 2380 dbSNP
rs1419419229 2391 dbSNP
rs1327282028 2393 dbSNP
rs1175153214 2403 dbSNP
rs1051424078 2407 dbSNP
rs1401480365 2417 dbSNP
rs1470951907 2421 dbSNP
rs1399666599 2431 dbSNP
rs933858569 2431 dbSNP
rs1331671779 2433 dbSNP
rs376097642 2434 dbSNP
rs918399270 2450 dbSNP
rs571226927 2451 dbSNP
rs941105275 2454 dbSNP
rs1403294906 2469 dbSNP
rs1326275878 2476 dbSNP
rs909589814 2493 dbSNP
rs1263162595 2498 dbSNP
rs990450698 2503 dbSNP
rs1171442877 2515 dbSNP
rs959266812 2519 dbSNP
rs753223551 2523 dbSNP
rs1234233439 2526 dbSNP
rs150015997 2538 dbSNP
rs184036267 2545 dbSNP
rs113831755 2546 dbSNP
rs1011030494 2561 dbSNP
rs74576731 2571 dbSNP
rs1172688205 2579 dbSNP
rs564164518 2581 dbSNP
rs1457654943 2587 dbSNP
rs749459666 2588 dbSNP
rs1347804682 2597 dbSNP
rs151251378 2598 dbSNP
rs1339156181 2615 dbSNP
rs1212280538 2617 dbSNP
rs754476216 2621 dbSNP
rs1238537769 2625 dbSNP
rs1200781194 2632 dbSNP
rs1029601125 2634 dbSNP
rs778068919 2639 dbSNP
rs1490789429 2653 dbSNP
rs569728309 2654 dbSNP
rs1474420168 2661 dbSNP
rs1201048719 2678 dbSNP
rs1188356001 2685 dbSNP
rs1347196557 2693 dbSNP
rs1278367257 2695 dbSNP
rs1269067618 2699 dbSNP
rs1161937708 2701 dbSNP
rs1367732268 2706 dbSNP
rs897025580 2715 dbSNP
rs1036820914 2719 dbSNP
rs941159119 2719 dbSNP
rs1240020403 2723 dbSNP
rs1271367971 2726 dbSNP
rs1362065322 2727 dbSNP
rs1244743444 2737 dbSNP
rs1312425951 2744 dbSNP
rs1378183020 2746 dbSNP
rs551330343 2747 dbSNP
rs1448573212 2752 dbSNP
rs75970052 2754 dbSNP
rs1332947483 2755 dbSNP
rs544448632 2758 dbSNP
rs575496425 2759 dbSNP
rs56197651 2763 dbSNP
rs1414602486 2771 dbSNP
rs1403679491 2773 dbSNP
rs1156791828 2778 dbSNP
rs1418966301 2780 dbSNP
rs1472490739 2781 dbSNP
rs1181875974 2782 dbSNP
rs937712494 2783 dbSNP
rs568991320 2785 dbSNP
rs561833390 2788 dbSNP
rs1158346292 2791 dbSNP
rs1406252731 2793 dbSNP
rs1402898422 2801 dbSNP
rs559579789 2803 dbSNP
rs1319596636 2805 dbSNP
rs546816143 2811 dbSNP
rs1359140290 2812 dbSNP
rs1237176855 2814 dbSNP
rs1451255072 2815 dbSNP
rs1334190801 2828 dbSNP
rs143635575 2833 dbSNP
rs1384540770 2834 dbSNP
rs190940597 2850 dbSNP
rs1278677572 2866 dbSNP
rs1225294488 2880 dbSNP
rs982414987 2881 dbSNP
rs945604219 2888 dbSNP
rs1201845659 2890 dbSNP
rs1245046666 2902 dbSNP
rs561020317 2903 dbSNP
rs111991984 2904 dbSNP
rs1471346446 2907 dbSNP
rs958163739 2908 dbSNP
rs1425067959 2911 dbSNP
rs1017720697 2928 dbSNP
rs1468764252 2946 dbSNP
rs1173547745 2953 dbSNP
rs986603191 2957 dbSNP
rs1452851957 2964 dbSNP
rs1327728170 2966 dbSNP
rs1333671963 2976 dbSNP
rs571298667 2979 dbSNP
rs954760142 2979 dbSNP
rs542953796 2982 dbSNP
rs1324403604 2987 dbSNP
rs768103474 2991 dbSNP
rs998150244 2997 dbSNP
rs1439838341 2999 dbSNP
rs1182978934 3022 dbSNP
rs1246495135 3025 dbSNP
rs1479710696 3034 dbSNP
rs1202255325 3055 dbSNP
rs897079349 3056 dbSNP
rs1469846408 3059 dbSNP
rs1244170786 3072 dbSNP
rs186018491 3074 dbSNP
rs1283275283 3078 dbSNP
rs1005356788 3079 dbSNP
rs1329225450 3086 dbSNP
rs1344658590 3088 dbSNP
rs888258556 3097 dbSNP
rs756078913 3101 dbSNP
rs1346131399 3102 dbSNP
rs937745490 3108 dbSNP
rs906233860 3122 dbSNP
rs1046486378 3127 dbSNP
rs182774018 3128 dbSNP
rs544657851 3135 dbSNP
rs989705901 3141 dbSNP
rs1202106128 3142 dbSNP
rs1270217137 3143 dbSNP
rs577708252 3144 dbSNP
rs936845133 3150 dbSNP
rs1370854517 3156 dbSNP
rs910697905 3159 dbSNP
rs1168165155 3160 dbSNP
rs1361025848 3164 dbSNP
rs986266593 3171 dbSNP
rs1304796203 3177 dbSNP
rs954955330 3178 dbSNP
rs76621365 3182 dbSNP
rs1293454064 3185 dbSNP
rs972483147 3187 dbSNP
rs961990965 3188 dbSNP
rs1015485092 3210 dbSNP
rs752805185 3212 dbSNP
rs952578332 3220 dbSNP
rs1473871112 3228 dbSNP
rs767392344 3229 dbSNP
rs1002000656 3231 dbSNP
rs1192960646 3236 dbSNP
rs1488913432 3238 dbSNP
rs1448186419 3244 dbSNP
rs1188692329 3246 dbSNP
rs754883636 3247 dbSNP
rs140023246 3249 dbSNP
rs190126559 3250 dbSNP
rs555503988 3262 dbSNP
rs1165169265 3264 dbSNP
rs1385650926 3267 dbSNP
rs146039009 3273 dbSNP
rs569990186 3274 dbSNP
rs1387101970 3278 dbSNP
rs1009254006 3285 dbSNP
rs551393482 3296 dbSNP
rs892116793 3300 dbSNP
rs1380769810 3307 dbSNP
rs1357939174 3310 dbSNP
rs1054066641 3312 dbSNP
rs539443670 3314 dbSNP
rs1316727158 3327 dbSNP
rs186147354 3331 dbSNP
rs1262990874 3341 dbSNP
rs1486514940 3344 dbSNP
rs1300004294 3347 dbSNP
rs777076539 3355 dbSNP
rs1459658252 3359 dbSNP
rs1434185156 3366 dbSNP
rs1256549471 3369 dbSNP
rs1418256455 3370 dbSNP
rs1156729956 3371 dbSNP
rs867572028 3384 dbSNP
rs1457708195 3396 dbSNP
rs766033789 3398 dbSNP
rs933469233 3405 dbSNP
rs1349114857 3416 dbSNP
rs751534655 3417 dbSNP
rs972100099 3431 dbSNP
rs962043966 3435 dbSNP
rs909204176 3440 dbSNP
rs766154858 3451 dbSNP
rs1223456918 3453 dbSNP
rs1261918690 3453 dbSNP
rs952738822 3461 dbSNP
rs1033564302 3467 dbSNP
rs1002456158 3473 dbSNP
rs1480143952 3474 dbSNP
rs1170226146 3481 dbSNP
rs1472849406 3485 dbSNP
rs1198636882 3486 dbSNP
rs1478229396 3488 dbSNP
rs970562264 3491 dbSNP
rs1176950410 3504 dbSNP
rs1025167021 3510 dbSNP
rs1300207329 3517 dbSNP
rs1425839350 3517 dbSNP
rs1460666550 3517 dbSNP
rs1351517186 3528 dbSNP
rs1337767213 3529 dbSNP
rs1404838328 3532 dbSNP
rs1197914146 3533 dbSNP
rs1347990184 3542 dbSNP
rs1009304849 3565 dbSNP
rs1247656937 3571 dbSNP
rs1306498326 3572 dbSNP
rs1202032233 3576 dbSNP
rs892170827 3580 dbSNP
rs1483240393 3600 dbSNP
rs1053446827 3602 dbSNP
rs1224164190 3603 dbSNP
rs62053140 3605 dbSNP
rs1423533615 3606 dbSNP
rs770852179 3607 dbSNP
rs77169995 3607 dbSNP
rs1000493137 3610 dbSNP
rs1426916331 3611 dbSNP
rs889372784 3613 dbSNP
rs1050672282 3615 dbSNP
rs1424401594 3623 dbSNP
rs933504726 3624 dbSNP
rs1491483804 3625 dbSNP
rs923446293 3625 dbSNP
rs1036434009 3626 dbSNP
rs1212329848 3626 dbSNP
rs1228110543 3626 dbSNP
rs1274872917 3626 dbSNP
rs1360699123 3626 dbSNP
rs1481239989 3626 dbSNP
rs1491161634 3626 dbSNP
rs200408040 3626 dbSNP
rs61081595 3626 dbSNP
rs777826107 3626 dbSNP
rs869063876 3626 dbSNP
rs1188408950 3627 dbSNP
rs372592612 3627 dbSNP
rs1391006457 3629 dbSNP
rs1444312965 3629 dbSNP
rs1161994985 3631 dbSNP
rs1387494102 3634 dbSNP
rs1406420188 3636 dbSNP
rs1318212163 3642 dbSNP
rs1279486893 3644 dbSNP
rs940774282 3645 dbSNP
rs1322047691 3650 dbSNP
rs1366741092 3651 dbSNP
rs1451482614 3656 dbSNP
rs554147781 3658 dbSNP
rs984759774 3660 dbSNP
rs1228718750 3665 dbSNP
rs1283446973 3666 dbSNP
rs1315118443 3671 dbSNP
rs376878493 3680 dbSNP
rs1218035946 3683 dbSNP
rs771264345 3684 dbSNP
rs1397847133 3685 dbSNP
rs1324725507 3689 dbSNP
rs1330982636 3690 dbSNP
rs1466292237 3699 dbSNP
rs1402581711 3701 dbSNP
rs1245243214 3711 dbSNP
rs533933000 3716 dbSNP
rs1433125049 3717 dbSNP
rs1158406455 3720 dbSNP
rs1402955046 3721 dbSNP
rs1406415637 3721 dbSNP
rs1160668038 3728 dbSNP
rs1426556025 3738 dbSNP
rs747396770 3742 dbSNP
rs1334254818 3746 dbSNP
rs970994264 3750 dbSNP
rs1024803849 3756 dbSNP
rs1278809355 3760 dbSNP
rs1371007678 3761 dbSNP
rs1230173162 3763 dbSNP
rs1268807028 3767 dbSNP
rs762823023 3769 dbSNP
rs1201904690 3770 dbSNP
rs1468960883 3778 dbSNP
rs1265214800 3787 dbSNP
rs1237930766 3789 dbSNP
rs1197651042 3801 dbSNP
rs1457903536 3802 dbSNP
rs1259434976 3805 dbSNP
rs1231539891 3807 dbSNP
rs772676779 3807 dbSNP
rs987927817 3809 dbSNP
rs1429255621 3813 dbSNP
rs557088452 3827 dbSNP
rs559913824 3827 dbSNP
rs745837890 3827 dbSNP
rs1403901585 3829 dbSNP
rs1207346199 3838 dbSNP
rs547580721 3840 dbSNP
rs1032059770 3842 dbSNP
rs1311093345 3844 dbSNP
rs1327882416 3846 dbSNP
rs1352574418 3850 dbSNP
rs1411471948 3855 dbSNP
rs1000545463 3856 dbSNP
rs1220846496 3867 dbSNP
rs1374413250 3875 dbSNP
rs529350029 3876 dbSNP
rs1276692075 3879 dbSNP
rs1345905623 3883 dbSNP
rs1308204718 3887 dbSNP
rs1271277280 3899 dbSNP
rs1484225565 3899 dbSNP
rs201592122 3899 dbSNP
rs567566257 3900 dbSNP
rs561082669 3902 dbSNP
rs1196566811 3905 dbSNP
rs1378876085 3911 dbSNP
rs1301303343 3915 dbSNP
rs577742950 3918 dbSNP
rs12927272 3923 dbSNP
rs902044074 3927 dbSNP
rs1418358566 3928 dbSNP
rs148459847 3930 dbSNP
rs1179579382 3935 dbSNP
rs940825278 3937 dbSNP
rs1325548890 3941 dbSNP
rs1331787492 3959 dbSNP
rs1226842627 3965 dbSNP
rs7199729 3973 dbSNP
rs887872054 3984 dbSNP
rs1049108161 3986 dbSNP
rs181460750 3989 dbSNP
rs1482668088 3994 dbSNP
rs762406127 3999 dbSNP
rs927301938 3999 dbSNP
rs768321465 4009 dbSNP
rs981128859 4014 dbSNP
rs949328968 4018 dbSNP
rs917800760 4019 dbSNP
rs1285055426 4020 dbSNP
rs1240669084 4026 dbSNP
rs1355578380 4028 dbSNP
rs569130551 4034 dbSNP
rs987980023 4034 dbSNP
rs1164899089 4037 dbSNP
rs1395645644 4039 dbSNP
rs1391428539 4041 dbSNP
rs577568245 4042 dbSNP
rs111237860 4047 dbSNP
rs1316398601 4047 dbSNP
rs955580625 4048 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000299980.4 | 3UTR | ACAUUUUCAUUAUGCCCCAUCACAUCUUCUUUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
115 hsa-miR-2681-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT058831 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT076301 ULK2 unc-51 like autophagy activating kinase 2 2 2
MIRT095503 PURA purine rich element binding protein A 2 12
MIRT097763 ARSK arylsulfatase family member K 2 2
MIRT170870 TAX1BP1 Tax1 binding protein 1 2 2
MIRT179045 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT189057 CLEC2D C-type lectin domain family 2 member D 2 8
MIRT241949 BTG1 BTG anti-proliferation factor 1 2 4
MIRT261860 ZRANB1 zinc finger RANBP2-type containing 1 2 2
MIRT309357 OTUD4 OTU deubiquitinase 4 2 2
MIRT340568 SMIM12 small integral membrane protein 12 2 4
MIRT351983 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT351986 MOB4 MOB family member 4, phocein 2 8
MIRT353140 RAB10 RAB10, member RAS oncogene family 2 2
MIRT387104 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT441833 SLC30A7 solute carrier family 30 member 7 2 2
MIRT443778 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 4
MIRT448135 CMTM6 CKLF like MARVEL transmembrane domain containing 6 2 2
MIRT450638 ZMYM2 zinc finger MYM-type containing 2 2 2
MIRT494763 AP1G1 adaptor related protein complex 1 gamma 1 subunit 2 2
MIRT498299 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT505104 YTHDC1 YTH domain containing 1 2 6
MIRT507179 G3BP2 G3BP stress granule assembly factor 2 2 6
MIRT516638 ZNF318 zinc finger protein 318 2 4
MIRT520011 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT526877 GJD3 gap junction protein delta 3 2 2
MIRT529374 SKP1 S-phase kinase associated protein 1 2 2
MIRT530090 SHISA2 shisa family member 2 2 2
MIRT536514 KCTD10 potassium channel tetramerization domain containing 10 2 2
MIRT536559 JMJD1C jumonji domain containing 1C 2 2
MIRT536624 IPO7 importin 7 2 2
MIRT544378 ZNF266 zinc finger protein 266 2 2
MIRT547590 LIN28B lin-28 homolog B 2 2
MIRT548736 CREBBP CREB binding protein 2 2
MIRT551485 TMEM192 transmembrane protein 192 2 4
MIRT552322 ZNF791 zinc finger protein 791 2 4
MIRT553193 UBE2A ubiquitin conjugating enzyme E2 A 2 2
MIRT553719 TBX18 T-box 18 2 2
MIRT554573 RRAS2 RAS related 2 2 2
MIRT557038 HOXB3 homeobox B3 2 2
MIRT559566 ARF1 ADP ribosylation factor 1 2 2
MIRT560134 INO80D INO80 complex subunit D 2 2
MIRT560406 JUN Jun proto-oncogene, AP-1 transcription factor subunit 2 2
MIRT561712 PTMA prothymosin, alpha 2 2
MIRT562688 ABI2 abl interactor 2 2 2
MIRT563214 FXN frataxin 2 2
MIRT566288 PROX1 prospero homeobox 1 2 4
MIRT567369 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT571380 JKAMP JNK1/MAPK8-associated membrane protein 2 2
MIRT574743 GOLGA4 golgin A4 2 2
MIRT576816 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT609984 ZHX1 zinc fingers and homeoboxes 1 2 4
MIRT610518 HIAT1 major facilitator superfamily domain containing 14A 2 2
MIRT612203 NKTR natural killer cell triggering receptor 2 4
MIRT612224 DHX33 DEAH-box helicase 33 2 6
MIRT612889 HOOK3 hook microtubule tethering protein 3 2 2
MIRT613639 DUSP18 dual specificity phosphatase 18 2 4
MIRT614161 PHF8 PHD finger protein 8 2 2
MIRT614630 WDR13 WD repeat domain 13 2 4
MIRT615001 FXR1 FMR1 autosomal homolog 1 2 4
MIRT615665 TSC22D2 TSC22 domain family member 2 2 2
MIRT615976 KAT6A lysine acetyltransferase 6A 2 2
MIRT616328 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT616495 AIPL1 aryl hydrocarbon receptor interacting protein like 1 2 2
MIRT616585 ZNF460 zinc finger protein 460 2 2
MIRT616870 ARPC1B actin related protein 2/3 complex subunit 1B 2 4
MIRT617631 RXRA retinoid X receptor alpha 2 2
MIRT620339 TLN1 talin 1 2 2
MIRT621658 UBE4B ubiquitination factor E4B 2 2
MIRT621824 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT622134 SOX4 SRY-box 4 2 2
MIRT622154 SNTG1 syntrophin gamma 1 2 2
MIRT622298 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT622531 RAB9B RAB9B, member RAS oncogene family 2 2
MIRT622596 PRRC2B proline rich coiled-coil 2B 2 2
MIRT623328 MAK16 MAK16 homolog 2 2
MIRT624499 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT624720 AP1S2 adaptor related protein complex 1 sigma 2 subunit 2 2
MIRT625990 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT626143 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT626499 ARHGAP9 Rho GTPase activating protein 9 2 2
MIRT627023 CREBL2 cAMP responsive element binding protein like 2 2 2
MIRT635710 HFM1 HFM1, ATP dependent DNA helicase homolog 2 2
MIRT635725 CCDC58 coiled-coil domain containing 58 2 2
MIRT637121 MKX mohawk homeobox 2 2
MIRT639969 POU5F1B POU class 5 homeobox 1B 2 2
MIRT640962 GPRASP1 G protein-coupled receptor associated sorting protein 1 2 4
MIRT641067 HHIPL1 HHIP like 1 2 2
MIRT644800 NKX3-2 NK3 homeobox 2 2 2
MIRT644958 STEAP4 STEAP4 metalloreductase 2 2
MIRT649152 LRTM1 leucine rich repeats and transmembrane domains 1 2 2
MIRT651887 UFD1L ubiquitin recognition factor in ER associated degradation 1 2 2
MIRT652165 TRIM66 tripartite motif containing 66 2 2
MIRT652565 TLR6 toll like receptor 6 2 2
MIRT653127 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT655622 ONECUT1 one cut homeobox 1 2 2
MIRT656245 MEX3A mex-3 RNA binding family member A 2 2
MIRT656837 KLF7 Kruppel like factor 7 2 2
MIRT656990 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT660337 BCL10 B-cell CLL/lymphoma 10 2 2
MIRT660393 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT660940 ACER3 alkaline ceramidase 3 2 2
MIRT661509 C8orf82 chromosome 8 open reading frame 82 2 2
MIRT665000 KLF2 Kruppel like factor 2 2 2
MIRT665106 TNFSF8 TNF superfamily member 8 2 2
MIRT665547 UCHL5 ubiquitin C-terminal hydrolase L5 2 2
MIRT687376 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT711828 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT713313 VLDLR very low density lipoprotein receptor 2 2
MIRT715654 PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K 2 2
MIRT715735 CD226 CD226 molecule 2 2
MIRT717255 SLC44A1 solute carrier family 44 member 1 2 2
MIRT717950 MIA3 MIA family member 3, ER export factor 2 2
MIRT719709 CD101 CD101 molecule 2 2
MIRT723893 NUDT21 nudix hydrolase 21 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-2681-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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