miRTarBase - #MIRT494804


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pre-miRNA Information
pre-miRNA hsa-mir-4318   
Genomic Coordinates chr18: 37657135 - 37657215
Description Homo sapiens miR-4318 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4318
Sequence 55| CACUGUGGGUACAUGCU |71
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs753426994 4 dbSNP
rs1218438067 17 dbSNP
Putative Targets

Gene Information
Gene Symbol ALG9   
Synonyms CDG1L, DIBD1, GIKANIS, LOH11CR1J
Description ALG9, alpha-1,2-mannosyltransferase
Transcript NM_001077690   
Other Transcripts NM_001077691 , NM_001077692 , NM_024740   
Expression
Putative miRNA Targets on ALG9
3'UTR of ALG9
(miRNA target sites are highlighted)		 
>ALG9|NM_001077690|3'UTR
   1 CAACACACCTGTGGCCCCAAAGGACAACCATCTTGTTAACTATTGATTCCAGTGACCTGACTCCCTGCAAGTCATCGCCT
  81 GTAACATTTGTAATAAAGGTCTTCTGACATGAATACTGGAATCTGGGTGCTCTGGGCTAGTCAAAGTCTATTTCAAAGTC
 161 TAATCAAAGTCACATTTGCTCCCTGTGTGTGTCTCTGTTCTGCATGTAAACTTTTTGCAGCTAGGCAGAGAAAGGCCCTA
 241 AAGCACAGATAGATATATTGCTCCACATCTCATTGTTTTTCCTCTGTTCAATTATTTACTAGACCGGAGAAGAGCAGAAC
 321 CAACTTACAGGAAGAATTGAAAATCCTGGTACTGGATGGCTGTGATAAGCTGTTCTCCACACTCTGGCCTGGCATCTGAG
 401 AACTAGCAAGCCTCTCTTAGGCCATATGGGCTTCTCCACCAAAGCTGTTTGGCAGCTCCTAGCAGACCTTCTTATTGAAA
 481 TCCTCATGCTGAAAATGAACACAGCCTAGTTGCCAACCCACATGTCCTTTTCACCTCCAGCAAGACTAAGCTTCTTTAAA
 561 GCACTTCACAGGACTAGGACCCTGTCCTGGAGCTATCTCAGGAAAAAGGTGACCATTTGAGGAACTGTGACCTAATTTTA
 641 TTATAATGATGCCTCTAATTTTCATTTCCTTTACAACCAACTGTAACTATAAGGTTGTATTGCTTTTTTGTTCAGTTTTA
 721 GCATGCTATTTTTTGAATTCTAGACTCCTCCATGTGAAGATATCAACAGACAAAACTACAACTGTATAGGACATATTTGG
 801 AGAAAATTCTATCAATTGATACATTTGGATGACATCACATTTTTAAGTAATGTAATCTGAGGCCATTGCTGAGGAAATTA
 881 AGAATTTTCCTTTTTTTTTAACCACCCCCAGTGAAAAGGATCAGTGTATATTTATAGCACCTATTTTTTAGTTCTGTCTG
 961 TTGTGAGGCACATCCTGCATGGGGCACTTCTAGTCAAATAGGCAATGATAAGGACCTAATTAAAATGTGATAAGTGTATA
1041 CTATTACTTTAAAAGCCTTTACAGTCAGTACTTCAGTTTACAAGGCACTTTCACAGCATCTCGTTTGATCCTCACAGTCA
1121 CAACATGTGGTAGACAAGGCAGGTGATTTTTATCCCCATTTTACAGATAAGGAAACAGGCTGCGGGTGGGGAGTGAGGGG
1201 AGGTAAAGATAGTTAGTTGCCTAAGGTCACACAGCCAGTAAGTAATAGAGCTGGGACTGGAACCCAGGTTTCCTTACTCT
1281 CATCTATTGCTCCTCCATATTCCTCACTCAACCATGAAAACATTACTTGAAAGGACTGATGAGGTTAACCAGAGACCTAA
1361 CTGATATTGTAACTTTCTATTTTAAGGAAGAATTGTGTCTGTATTTGAGTTCTTTGGAGCCTCCAGTCTGCCTGTGTGTT
1441 AGACCAGCACAGCAGTGCTGTGTGATGCAGCCTGACCTGTGGCAGGAAAGTAGTGCTTCTGTTTGGAAGTCATGTTCTTT
1521 TGCAGCCACACAGGATCCAAATATCAGTACTATTCCTGTAGTCAATCTGGGGTCACATTATAGGTGCCTTATTTCCCTAA
1601 GGGTAACTGATCTGAATATCTGCAAATAGGATGAATCTATTTTTCAGAAGTTCCATCTTTCATTTTTCTTTTTTTTTTTG
1681 AGACAGAGTCTCATTCTGTCGCCCATGCTGGAGTGCAGTGGCGCGATCTCGGCTCGCTGCAACCTCTGCCTCCCAGGTTG
1761 AAGCAATTCTCATGCCTCAGCCACCCGAGTAGCTGGGATTACAGGCATGCGCCATCATGCCCAGCTAATTTATGTATTTT
1841 TAGTAGAGTTGGAGTTTCACCATGTTGGCCAGGCTGGTCTTGGACTCCTGACCTCAGGTCATCCACCCGCCTCAGCCTCC
1921 CAAAGTGCTGGTATTACAGGCGTGAGCCACCGCACCCAGCCCCATCTTTCATTTTCAAAGAGAAGGGCATTCTAATAGGA
2001 ACTGGTGCCAAGAGAGAAGAAAAGAAGTGATAACAGAAGAAATGGCTAGTTACAATATTAAAAAGCTCCTCTTTGAGATC
2081 TCCTCTGCAGGAATATCAGAGACGGAGTTGAAGCGCTGGAGAGGTAATAGGTCTAGACAGTACAGAACAATAACTGGGGA
2161 GTGTGTGAGGATAGACTGGGCTCCCCCTTGCTTGAAAGATCTCTGGCATTTAATTCTCAATTCTTGATTACTATTTTCCA
2241 GTGTAAAACTAGCACATATGATCTGACTACAGGACAGAGAATTTTAAGTGAAACATTTGCCTTACTTGCAGTAATAATGT
2321 GCTGTTCTTCACAGTAGCTAAGGCCCTCTATGTTTCCCAGAGGTAAATAAGAATCCAGGAATGGAGGTCCATCTGTGATG
2401 AATGGCTTTTTTCTAATCAAAGTAGTATAATGCTGTTTTATCTGTTTTGTCATCTTGTTTTTTTTTTTTTTTAAAAAAAC
2481 AAAACCTTAATTATAATATAGCGCAAAGAAAGGCCAGGACTGATGCAGGGATTCCTTGGAAATATCAGTTCCTATCACTT
2561 TTAAAACCTGATTTTGGATCTCTCTGTTCTATGTATGTCTTTAGTGAGAGCACAATACATGGCAGAACGCTGTGCCAAAT
2641 GTTATAGGTAAGGAATATAGAAATGAATGTTTTTTGTTGTGAAGGTGTTTTCATGTGATATTTTATAAACACATTTTAAA
2721 AAATCTCCATCACTTTTTAGTATAGGAAGGATAGCTTTGCCTGGGAAAAACAGTTTCAACACACCTGCTCAGAGTAGCAG
2801 TTCTCCCTCAAAAAAGCAGTGTTCAGCCTGCACTGACTGTTCTGCTTGCCAAAAGGAGGAAGCATGCAAGATACTTATTT
2881 CTCCATAGATTGTGGAGTATAGAGGGATGTGGGACTACAGATTATTATTTTTTTTCCCCGAGACAGAGTCTTGCTCTGTC
2961 GCCCAGGTTGGAACACAATGGCACGACCTCAGCTCACTGCAACCTCTGTCTCCCGGGTTCAAGCAATTCTCCTGCTTCAG
3041 CCTCCTGAGTAGCTGGGATTACAGGCACACACCACCACCGCACTCAGCTAATTTTTGTATTTTTAGTAGAGGTGGGGTTT
3121 TACCATGTTGGCCAGGCTGGTCTTAAACTCCTGACCTTGTAATCATCCCGCCTCGGCCTCCTAAAGTGCTAGGATTACAG
3201 GCATGAGCCACCGCACCCGGCCCAGATAATTTTTAATAGCCTTTGATCATGGGGTGAGTGAGGGAGTAGGTATACTTGGC
3281 AAATGCATGGTTCTCTGATTTCTAGCTCTAAAGCAGCCTTATCTGAATCCCCAAATCTTGTGATGCTGAGTACCATTACT
3361 GAACCAGTCTGCACGGTAGGCATCTGCTACCAAAATTTACCTCCTACCTGGTAGGTGTCATCTGATAAGAAAGAAGACAG
3441 GTTATTTTAATTTTTTGAGATAATCACAGAAAATTGCAGCCCATACTCTTTATTACCGAATTCAAGTTTGGAAATAGACC
3521 CTTTGTTTTAAATCATGATGGGTCTTTATCCCAATCATTTATCTGGGTCATTTTTCCAACTTTGGAGTTCTAGGAAAGAA
3601 CCTTGAAAACCTGATATGATTCTGCAGCATGAGGTCTACGGTGACCATTTGGGCAAAGCTCCAGTGGCAATCATTTATTG
3681 TGTTTTGCATTTCCTGGGATTTATTGAAATAAGAATTCACTGTGATTATGTAGTCTTCTGGCTAGTATCAGGCAGCTCTG
3761 CTTTTAATTTGGTTAATTTTATTTTCTCTGAAGAGGGAGAAGAGGTACAATTTAATCTTGGCCTCCACAAGCATATTAAA
3841 GCTCACGTGTTAATCAGTGCATTCTTATGCTCCTACATTAAATGCCTTGGGTAAATGGATAAATGGACATGTGCCCAGCT
3921 TTAATTTTTTTTGCAACAGAAAGATCAGACTTCCGTATGGCATCGTTGGATTTCAGAGGCTTTCTGGTGTATCTGTAAAT
4001 CTGAATGTTGCCTTCTGCCAGTCTGTATAACCAGGTGATTCATGCTGCAAATGAAATCAGGAAGCAGTAAAGTGTTAAAG
4081 CAAGAGTATTGTCCAATTCACTTGTCTTCCTGATCCTTGTACTTTATTTCACGTGTCGGTGTTTACATTACATACTTATA
4161 TTTCCTGTGAAAGAAAGAGTTAAATAAATTGTAGCAGTTTGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucguAC-AUGGGUGUCAc 5'
              || | |:|||||| 
Target 5' cgttTGATCCTCACAGTc 3'
 1102 - 1119 133.00 -9.20
2 
miRNA  3' ucguACAUG-GGUGUCAc 5'
              ||| | :|||||| 
Target 5' gtgcTGTTCTTCACAGTa 3'
 2319 - 2336 133.00 -10.50
3 
miRNA  3' ucGUAC-AUGGGUGUCAc 5'
            ||||  ::|:||:|| 
Target 5' agCATGAGGTCTACGGTg 3'
 3626 - 3643 119.00 -19.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
878961 77 ClinVar
302424 229 ClinVar
302423 243 ClinVar
878372 305 ClinVar
302422 306 ClinVar
878371 314 ClinVar
302421 365 ClinVar
302420 523 ClinVar
302419 532 ClinVar
878370 726 ClinVar
302418 763 ClinVar
302417 773 ClinVar
302416 788 ClinVar
302415 823 ClinVar
302414 906 ClinVar
302413 971 ClinVar
302412 1219 ClinVar
302411 1220 ClinVar
877347 1297 ClinVar
302410 1307 ClinVar
877346 1311 ClinVar
302409 1420 ClinVar
302408 1536 ClinVar
302407 1607 ClinVar
302406 1624 ClinVar
880136 1671 ClinVar
302403 1680 ClinVar
302404 1680 ClinVar
302405 1680 ClinVar
302402 1682 ClinVar
302401 1687 ClinVar
880135 1722 ClinVar
302400 1766 ClinVar
302399 1832 ClinVar
302398 1848 ClinVar
302397 1977 ClinVar
302396 2012 ClinVar
302395 2114 ClinVar
302394 2230 ClinVar
302393 2233 ClinVar
878913 2287 ClinVar
302392 2339 ClinVar
878331 2342 ClinVar
878330 2414 ClinVar
302391 2443 ClinVar
878329 2443 ClinVar
302390 2445 ClinVar
302389 2450 ClinVar
302388 2457 ClinVar
878328 2457 ClinVar
302387 2458 ClinVar
302386 2472 ClinVar
302385 2473 ClinVar
302384 2474 ClinVar
878327 2474 ClinVar
302383 2475 ClinVar
302382 2480 ClinVar
302381 2481 ClinVar
302380 2482 ClinVar
302379 2501 ClinVar
302378 2592 ClinVar
877293 2597 ClinVar
877292 2648 ClinVar
302377 2743 ClinVar
302376 2907 ClinVar
302375 3079 ClinVar
302374 3125 ClinVar
877291 3175 ClinVar
302373 3212 ClinVar
880095 3213 ClinVar
302372 3359 ClinVar
302371 3423 ClinVar
302370 3441 ClinVar
880094 3471 ClinVar
302369 3519 ClinVar
880093 3750 ClinVar
880092 3757 ClinVar
880091 3798 ClinVar
302368 3955 ClinVar
302367 4141 ClinVar
COSN31544124 22 COSMIC
COSN30529649 37 COSMIC
COSN30529614 41 COSMIC
COSN19768321 52 COSMIC
COSN30178751 52 COSMIC
COSN30499326 57 COSMIC
COSN30464856 64 COSMIC
COSN30160283 73 COSMIC
COSN13300447 76 COSMIC
COSN19750462 77 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781974427 4 dbSNP
rs1252269085 6 dbSNP
rs561999267 9 dbSNP
rs1483946495 14 dbSNP
rs1179759606 19 dbSNP
rs950034435 22 dbSNP
rs782139868 23 dbSNP
rs377269069 42 dbSNP
rs782427530 49 dbSNP
rs1166223682 50 dbSNP
rs782202635 64 dbSNP
rs1423604506 66 dbSNP
rs782530816 68 dbSNP
rs937962243 69 dbSNP
rs1411992981 73 dbSNP
rs1296843417 75 dbSNP
rs782612113 76 dbSNP
rs984910253 77 dbSNP
rs613409 88 dbSNP
rs952153207 93 dbSNP
rs540183457 102 dbSNP
rs782498056 104 dbSNP
rs1275544837 105 dbSNP
rs1344584461 122 dbSNP
rs186101233 144 dbSNP
rs557909277 148 dbSNP
rs966713273 150 dbSNP
rs1443422706 167 dbSNP
rs782752834 176 dbSNP
rs546240495 178 dbSNP
rs1391589481 182 dbSNP
rs1427449662 187 dbSNP
rs1168750997 191 dbSNP
rs1354357609 193 dbSNP
rs1449388866 199 dbSNP
rs782260083 202 dbSNP
rs782665461 221 dbSNP
rs782550945 222 dbSNP
rs1298457101 223 dbSNP
rs781789551 229 dbSNP
rs1213078008 236 dbSNP
rs886047684 243 dbSNP
rs868962508 249 dbSNP
rs782728364 254 dbSNP
rs1272022610 256 dbSNP
rs1312620376 256 dbSNP
rs1211998019 273 dbSNP
rs1032633304 283 dbSNP
rs1000381108 290 dbSNP
rs1460840546 291 dbSNP
rs782183793 305 dbSNP
rs886047683 306 dbSNP
rs781928817 314 dbSNP
rs1185637911 320 dbSNP
rs74786079 323 dbSNP
rs1415343495 328 dbSNP
rs895732066 334 dbSNP
rs782220574 337 dbSNP
rs1404485128 351 dbSNP
rs1469755669 360 dbSNP
rs886047682 365 dbSNP
rs1055679011 366 dbSNP
rs1391015725 374 dbSNP
rs1428876341 375 dbSNP
rs1269770819 386 dbSNP
rs1368584031 394 dbSNP
rs1220700989 399 dbSNP
rs782478525 407 dbSNP
rs1281167995 424 dbSNP
rs1322705502 424 dbSNP
rs1209324377 429 dbSNP
rs937237517 447 dbSNP
rs1269472996 452 dbSNP
rs926642538 453 dbSNP
rs1444836437 457 dbSNP
rs781852722 464 dbSNP
rs1214474581 474 dbSNP
rs1246859730 486 dbSNP
rs1478822163 490 dbSNP
rs1201976103 499 dbSNP
rs1427696280 503 dbSNP
rs557562612 503 dbSNP
rs1480376773 508 dbSNP
rs1160632254 514 dbSNP
rs984774762 521 dbSNP
rs536072357 523 dbSNP
rs1398960959 528 dbSNP
rs886047681 532 dbSNP
rs782775014 533 dbSNP
rs1350637680 535 dbSNP
rs1438937308 546 dbSNP
rs568705521 550 dbSNP
rs919325782 552 dbSNP
rs1228916197 553 dbSNP
rs565447725 559 dbSNP
rs180893781 561 dbSNP
rs1290073528 573 dbSNP
rs966202591 577 dbSNP
rs535046660 578 dbSNP
rs1348460645 580 dbSNP
rs1222664361 612 dbSNP
rs1289993356 621 dbSNP
rs1452949996 626 dbSNP
rs566422482 642 dbSNP
rs1267199696 643 dbSNP
rs912059792 663 dbSNP
rs115171254 669 dbSNP
rs1366021359 680 dbSNP
rs953617132 681 dbSNP
rs539117752 682 dbSNP
rs568624560 691 dbSNP
rs1158045504 716 dbSNP
rs1414677485 726 dbSNP
rs1407293498 735 dbSNP
rs550292956 740 dbSNP
rs1365201257 742 dbSNP
rs967548381 744 dbSNP
rs782146661 745 dbSNP
rs1014508225 747 dbSNP
rs1309655167 754 dbSNP
rs886047680 763 dbSNP
rs886047679 773 dbSNP
rs1284239639 787 dbSNP
rs559698025 788 dbSNP
rs561778889 789 dbSNP
rs1243160522 791 dbSNP
rs1342475749 793 dbSNP
rs1206257082 797 dbSNP
rs1253166772 799 dbSNP
rs1436548410 801 dbSNP
rs782031862 805 dbSNP
rs1181805489 811 dbSNP
rs1238116020 812 dbSNP
rs546866846 815 dbSNP
rs1161753855 819 dbSNP
rs1430666551 822 dbSNP
rs528387467 823 dbSNP
rs1394113645 832 dbSNP
rs1409294865 833 dbSNP
rs1334673763 856 dbSNP
rs564460643 862 dbSNP
rs1049547563 866 dbSNP
rs930632364 868 dbSNP
rs919342459 869 dbSNP
rs1449787908 873 dbSNP
rs1313771737 899 dbSNP
rs1230211311 900 dbSNP
rs35701057 900 dbSNP
rs147670080 906 dbSNP
rs1195599984 911 dbSNP
rs1279872928 918 dbSNP
rs1463076164 919 dbSNP
rs944779965 920 dbSNP
rs145612535 925 dbSNP
rs912091463 928 dbSNP
rs1450287421 936 dbSNP
rs1195681889 937 dbSNP
rs1371113399 941 dbSNP
rs1172979502 943 dbSNP
rs781958520 951 dbSNP
rs1408152379 953 dbSNP
rs986244869 954 dbSNP
rs953650030 960 dbSNP
rs1388820619 968 dbSNP
rs140187723 971 dbSNP
rs1292927901 972 dbSNP
rs1325491985 973 dbSNP
rs1227098369 981 dbSNP
rs978844384 984 dbSNP
rs1275833692 988 dbSNP
rs1326246473 1002 dbSNP
rs1202366568 1022 dbSNP
rs1262581474 1027 dbSNP
rs1465443957 1030 dbSNP
rs1206981673 1032 dbSNP
rs1259869695 1034 dbSNP
rs1428169405 1038 dbSNP
rs967033739 1040 dbSNP
rs151336511 1042 dbSNP
rs1014037482 1043 dbSNP
rs538024844 1055 dbSNP
rs782370096 1057 dbSNP
rs1175691791 1067 dbSNP
rs1412640923 1071 dbSNP
rs1454831110 1075 dbSNP
rs1286642540 1080 dbSNP
rs1383733432 1083 dbSNP
rs959762266 1084 dbSNP
rs1034205685 1088 dbSNP
rs1001344609 1102 dbSNP
rs888377620 1103 dbSNP
rs782246582 1115 dbSNP
rs995249022 1119 dbSNP
rs897861096 1125 dbSNP
rs1222204503 1138 dbSNP
rs1283137281 1143 dbSNP
rs1330468497 1152 dbSNP
rs1241217042 1157 dbSNP
rs575083155 1158 dbSNP
rs1259093410 1183 dbSNP
rs1485647660 1186 dbSNP
rs1210736840 1188 dbSNP
rs1036759496 1212 dbSNP
rs782005983 1213 dbSNP
rs782618635 1219 dbSNP
rs886047678 1219 dbSNP
rs114406340 1220 dbSNP
rs1252394750 1229 dbSNP
rs1420826943 1250 dbSNP
rs1156280631 1265 dbSNP
rs1362751960 1266 dbSNP
rs782408638 1270 dbSNP
rs576592817 1275 dbSNP
rs535275754 1277 dbSNP
rs370331303 1279 dbSNP
rs1302949992 1281 dbSNP
rs1374663390 1282 dbSNP
rs926212272 1286 dbSNP
rs577487864 1297 dbSNP
rs782298169 1307 dbSNP
rs912924184 1311 dbSNP
rs992883473 1314 dbSNP
rs142395344 1315 dbSNP
rs1246826936 1317 dbSNP
rs752090948 1328 dbSNP
rs1034071398 1329 dbSNP
rs539029702 1332 dbSNP
rs148777719 1341 dbSNP
rs1221394398 1344 dbSNP
rs1252329708 1347 dbSNP
rs952484775 1357 dbSNP
rs797029711 1359 dbSNP
rs375735185 1363 dbSNP
rs1249192975 1367 dbSNP
rs550255899 1368 dbSNP
rs994128483 1376 dbSNP
rs1382954976 1379 dbSNP
rs1423662144 1385 dbSNP
rs1163303432 1388 dbSNP
rs188040585 1389 dbSNP
rs1355547552 1391 dbSNP
rs782448248 1393 dbSNP
rs1014944326 1399 dbSNP
rs1373257441 1401 dbSNP
rs568209737 1402 dbSNP
rs1317278746 1403 dbSNP
rs890550809 1404 dbSNP
rs782226935 1412 dbSNP
rs143933458 1420 dbSNP
rs1273441309 1421 dbSNP
rs1309098609 1424 dbSNP
rs1202197881 1438 dbSNP
rs1250622275 1439 dbSNP
rs1483551059 1447 dbSNP
rs782624166 1454 dbSNP
rs1240772768 1458 dbSNP
rs1443627852 1460 dbSNP
rs1188876598 1467 dbSNP
rs1421227644 1469 dbSNP
rs782527346 1476 dbSNP
rs1168818865 1477 dbSNP
rs1354410474 1486 dbSNP
rs1470615270 1491 dbSNP
rs781881825 1497 dbSNP
rs1338740922 1501 dbSNP
rs1404080168 1508 dbSNP
rs1452174014 1512 dbSNP
rs904721663 1519 dbSNP
rs1043602882 1521 dbSNP
rs1212545408 1522 dbSNP
rs1294650391 1531 dbSNP
rs946341219 1532 dbSNP
rs782678326 1536 dbSNP
rs992506828 1538 dbSNP
rs528361665 1541 dbSNP
rs1460442170 1563 dbSNP
rs1215893670 1574 dbSNP
rs1243453190 1575 dbSNP
rs1484703356 1577 dbSNP
rs782434502 1580 dbSNP
rs938293889 1584 dbSNP
rs927031268 1587 dbSNP
rs979887381 1606 dbSNP
rs117488631 1607 dbSNP
rs117091304 1624 dbSNP
rs1319098679 1632 dbSNP
rs776627555 1639 dbSNP
rs1428936289 1643 dbSNP
rs961332088 1655 dbSNP
rs1288069359 1666 dbSNP
rs116003998 1671 dbSNP
rs1225134992 1673 dbSNP
rs1281231849 1676 dbSNP
rs1322777570 1678 dbSNP
rs150703313 1680 dbSNP
rs563719515 1680 dbSNP
rs886047677 1680 dbSNP
rs541176886 1682 dbSNP
rs367569393 1687 dbSNP
rs1267332521 1689 dbSNP
rs542301482 1700 dbSNP
rs782103178 1701 dbSNP
rs1477999910 1714 dbSNP
rs574839296 1720 dbSNP
rs186477879 1722 dbSNP
rs541280594 1724 dbSNP
rs1158582506 1725 dbSNP
rs1366437257 1729 dbSNP
rs577399597 1730 dbSNP
rs1301091728 1734 dbSNP
rs904586525 1735 dbSNP
rs1442883222 1736 dbSNP
rs1280779221 1741 dbSNP
rs1370607850 1743 dbSNP
rs1043246533 1745 dbSNP
rs1222715858 1750 dbSNP
rs558800800 1759 dbSNP
rs886047676 1766 dbSNP
rs782776196 1771 dbSNP
rs1225120986 1774 dbSNP
rs1290094053 1786 dbSNP
rs1451535551 1787 dbSNP
rs1183238270 1797 dbSNP
rs1235117982 1802 dbSNP
rs892055215 1809 dbSNP
rs1468610945 1810 dbSNP
rs113409957 1811 dbSNP
rs1386043930 1813 dbSNP
rs1426849365 1814 dbSNP
rs938910845 1823 dbSNP
rs1161404687 1824 dbSNP
rs1364803080 1827 dbSNP
rs926979351 1829 dbSNP
rs772136205 1832 dbSNP
rs45620134 1848 dbSNP
rs782038696 1849 dbSNP
rs1440782915 1851 dbSNP
rs1315164549 1855 dbSNP
rs574882570 1858 dbSNP
rs919642234 1862 dbSNP
rs1243403847 1864 dbSNP
rs972600588 1882 dbSNP
rs1313356711 1884 dbSNP
rs1356019794 1885 dbSNP
rs868978237 1891 dbSNP
rs1275676782 1895 dbSNP
rs1436606521 1907 dbSNP
rs556550557 1908 dbSNP
rs1243870532 1909 dbSNP
rs1446663813 1916 dbSNP
rs1182039160 1918 dbSNP
rs1368124657 1920 dbSNP
rs912394074 1921 dbSNP
rs986716229 1923 dbSNP
rs953953913 1931 dbSNP
rs535132621 1940 dbSNP
rs1336815350 1941 dbSNP
rs996108893 1942 dbSNP
rs568087425 1943 dbSNP
rs553100335 1944 dbSNP
rs1022094155 1946 dbSNP
rs781949750 1951 dbSNP
rs782378345 1952 dbSNP
rs1272340565 1961 dbSNP
rs1337984798 1962 dbSNP
rs891998484 1970 dbSNP
rs181231005 1977 dbSNP
rs375953398 1980 dbSNP
rs1462660926 1984 dbSNP
rs1201853335 1986 dbSNP
rs1255683394 1990 dbSNP
rs534577430 2012 dbSNP
rs886047675 2012 dbSNP
rs1195033211 2015 dbSNP
rs1371166544 2030 dbSNP
rs1003150731 2033 dbSNP
rs906090588 2045 dbSNP
rs1177001457 2052 dbSNP
rs1431359370 2055 dbSNP
rs1467738876 2060 dbSNP
rs1044098206 2062 dbSNP
rs1385203772 2068 dbSNP
rs190137837 2083 dbSNP
rs1383605003 2084 dbSNP
rs1320695049 2086 dbSNP
rs930940987 2091 dbSNP
rs1399792138 2093 dbSNP
rs1284407719 2103 dbSNP
rs919690385 2103 dbSNP
rs1326316557 2104 dbSNP
rs1221710793 2105 dbSNP
rs1255536325 2107 dbSNP
rs45452093 2114 dbSNP
rs939780733 2115 dbSNP
rs1259933536 2116 dbSNP
rs552498259 2135 dbSNP
rs530868929 2136 dbSNP
rs1199922598 2138 dbSNP
rs1270901951 2138 dbSNP
rs912426725 2141 dbSNP
rs1479446221 2143 dbSNP
rs1174711464 2148 dbSNP
rs570017017 2154 dbSNP
rs986575733 2158 dbSNP
rs1363946329 2159 dbSNP
rs1455007430 2188 dbSNP
rs953979845 2198 dbSNP
rs1359497062 2211 dbSNP
rs1419435709 2213 dbSNP
rs921150488 2224 dbSNP
rs372442946 2229 dbSNP
rs116530919 2230 dbSNP
rs886047674 2233 dbSNP
rs1300673332 2234 dbSNP
rs530175499 2241 dbSNP
rs1241281565 2242 dbSNP
rs1259145418 2259 dbSNP
rs1353289763 2267 dbSNP
rs1222928547 2270 dbSNP
rs1293726491 2273 dbSNP
rs200635723 2279 dbSNP
rs969084066 2284 dbSNP
rs185264895 2287 dbSNP
rs1251166581 2292 dbSNP
rs1420280076 2298 dbSNP
rs1179085764 2305 dbSNP
rs1379248690 2309 dbSNP
rs1010771045 2313 dbSNP
rs1424953398 2315 dbSNP
rs956135322 2319 dbSNP
rs1164571491 2327 dbSNP
rs1035879879 2328 dbSNP
rs191957403 2332 dbSNP
rs886047673 2339 dbSNP
rs532591210 2342 dbSNP
rs782179097 2343 dbSNP
rs995771903 2350 dbSNP
rs898190980 2368 dbSNP
rs1036689828 2375 dbSNP
rs1307241110 2387 dbSNP
rs1376402382 2398 dbSNP
rs1247083786 2410 dbSNP
rs782579858 2413 dbSNP
rs189536081 2414 dbSNP
rs1220559197 2425 dbSNP
rs543666420 2439 dbSNP
rs146821834 2443 dbSNP
rs886047672 2443 dbSNP
rs59753794 2444 dbSNP
rs886047671 2445 dbSNP
rs60302088 2446 dbSNP
rs368900847 2449 dbSNP
rs781847191 2449 dbSNP
rs886047670 2450 dbSNP
rs72428193 2452 dbSNP
rs782504561 2452 dbSNP
rs57848382 2456 dbSNP
rs201995459 2457 dbSNP
rs886047669 2457 dbSNP
rs58531246 2458 dbSNP
rs782521125 2458 dbSNP
rs886047668 2458 dbSNP
rs1383009569 2460 dbSNP
rs1422392435 2461 dbSNP
rs1164547513 2462 dbSNP
rs1374119336 2467 dbSNP
rs886047667 2472 dbSNP
rs1399727493 2473 dbSNP
rs1453493949 2473 dbSNP
rs2554994 2473 dbSNP
rs1377279967 2474 dbSNP
rs376483443 2474 dbSNP
rs886047666 2474 dbSNP
rs576333435 2475 dbSNP
rs782815611 2475 dbSNP
rs886047665 2475 dbSNP
rs1309151334 2480 dbSNP
rs376955296 2480 dbSNP
rs76179441 2480 dbSNP
rs781953022 2480 dbSNP
rs1461330142 2481 dbSNP
rs886047664 2481 dbSNP
rs886047663 2482 dbSNP
rs201094554 2496 dbSNP
rs1205051642 2497 dbSNP
rs3833761 2501 dbSNP
rs66517706 2501 dbSNP
rs782130424 2501 dbSNP
rs886047662 2501 dbSNP
rs1482753175 2502 dbSNP
rs1181610652 2503 dbSNP
rs1050897210 2515 dbSNP
rs1262954992 2518 dbSNP
rs1430800850 2528 dbSNP
rs932451638 2545 dbSNP
rs1423540377 2552 dbSNP
rs1470319455 2557 dbSNP
rs371690267 2568 dbSNP
rs1357616983 2572 dbSNP
rs1447624250 2576 dbSNP
rs1289224152 2590 dbSNP
rs886047661 2592 dbSNP
rs979796657 2593 dbSNP
rs782632372 2595 dbSNP
rs1277441654 2596 dbSNP
rs1324216311 2604 dbSNP
rs1224796851 2618 dbSNP
rs556511894 2619 dbSNP
rs541479085 2628 dbSNP
rs988805305 2629 dbSNP
rs956121526 2639 dbSNP
rs1489439444 2645 dbSNP
rs782820061 2647 dbSNP
rs1191986922 2653 dbSNP
rs1263033492 2656 dbSNP
rs1481077172 2658 dbSNP
rs1201643221 2659 dbSNP
rs1423233334 2660 dbSNP
rs782050063 2667 dbSNP
rs1160030717 2676 dbSNP
rs1347184223 2683 dbSNP
rs1035744384 2686 dbSNP
rs1297407484 2695 dbSNP
rs1346036167 2697 dbSNP
rs1406770905 2698 dbSNP
rs981610369 2700 dbSNP
rs1366223106 2710 dbSNP
rs1223860853 2717 dbSNP
rs1285863475 2718 dbSNP
rs558458258 2732 dbSNP
rs574409359 2740 dbSNP
rs139048490 2743 dbSNP
rs1490654635 2752 dbSNP
rs1224501934 2767 dbSNP
rs550984080 2779 dbSNP
rs1477701175 2790 dbSNP
rs781916324 2794 dbSNP
rs1410414365 2803 dbSNP
rs1438110157 2811 dbSNP
rs1366029038 2842 dbSNP
rs1426336053 2858 dbSNP
rs1321436890 2862 dbSNP
rs996191556 2864 dbSNP
rs1442231634 2872 dbSNP
rs898731110 2878 dbSNP
rs1374156814 2883 dbSNP
rs570546178 2892 dbSNP
rs1003851658 2897 dbSNP
rs1360540995 2900 dbSNP
rs1212007506 2902 dbSNP
rs782731018 2907 dbSNP
rs1451588161 2924 dbSNP
rs1050761346 2927 dbSNP
rs1205271686 2937 dbSNP
rs932399526 2939 dbSNP
rs1456603730 2940 dbSNP
rs1178201586 2949 dbSNP
rs558787580 2960 dbSNP
rs1473635746 2961 dbSNP
rs1161261910 2962 dbSNP
rs537313210 2964 dbSNP
rs1043554396 2971 dbSNP
rs946648301 2973 dbSNP
rs782116738 2981 dbSNP
rs569981334 2984 dbSNP
rs1336905752 2985 dbSNP
rs1384583956 2995 dbSNP
rs1247411790 2997 dbSNP
rs1282834890 3002 dbSNP
rs1356256665 3008 dbSNP
rs1215731716 3012 dbSNP
rs934610656 3014 dbSNP
rs548536674 3015 dbSNP
rs1243927787 3022 dbSNP
rs184805717 3026 dbSNP
rs781997646 3029 dbSNP
rs1185098404 3030 dbSNP
rs566109430 3031 dbSNP
rs1236748786 3034 dbSNP
rs1475691402 3038 dbSNP
rs1023580752 3044 dbSNP
rs974246730 3056 dbSNP
rs1421393864 3066 dbSNP
rs1464612008 3069 dbSNP
rs1176549771 3073 dbSNP
rs963299883 3076 dbSNP
rs1015811155 3078 dbSNP
rs886047660 3079 dbSNP
rs547562988 3080 dbSNP
rs1431942749 3081 dbSNP
rs532646435 3085 dbSNP
rs955079986 3087 dbSNP
rs1218064385 3088 dbSNP
rs1263872856 3091 dbSNP
rs1347390254 3097 dbSNP
rs1199004523 3100 dbSNP
rs1278201313 3104 dbSNP
rs1447295676 3107 dbSNP
rs782157531 3109 dbSNP
rs1195615943 3112 dbSNP
rs565092770 3117 dbSNP
rs1260872879 3123 dbSNP
rs547384257 3125 dbSNP
rs781914413 3140 dbSNP
rs899573127 3144 dbSNP
rs1464118484 3148 dbSNP
rs1171567038 3155 dbSNP
rs191550009 3169 dbSNP
rs1300491714 3170 dbSNP
rs1010706076 3174 dbSNP
rs146182772 3175 dbSNP
rs543334408 3178 dbSNP
rs1283984573 3188 dbSNP
rs1332846454 3189 dbSNP
rs1231163663 3208 dbSNP
rs528920657 3212 dbSNP
rs939244636 3213 dbSNP
rs1218490355 3218 dbSNP
rs928649794 3219 dbSNP
rs1487915022 3220 dbSNP
rs1223060124 3221 dbSNP
rs777495761 3239 dbSNP
rs782383121 3242 dbSNP
rs574348486 3246 dbSNP
rs552975348 3251 dbSNP
rs1364000943 3263 dbSNP
rs1441201145 3266 dbSNP
rs948803210 3271 dbSNP
rs915966978 3272 dbSNP
rs1160815445 3276 dbSNP
rs1359089436 3282 dbSNP
rs1419492411 3301 dbSNP
rs1294561059 3308 dbSNP
rs974652398 3310 dbSNP
rs1385104275 3317 dbSNP
rs962869651 3321 dbSNP
rs908699412 3329 dbSNP
rs983028650 3333 dbSNP
rs1307364331 3339 dbSNP
rs540729479 3343 dbSNP
rs1246477941 3344 dbSNP
rs1267089206 3352 dbSNP
rs577034367 3353 dbSNP
rs1487490728 3355 dbSNP
rs782323400 3359 dbSNP
rs1250704129 3370 dbSNP
rs558748989 3374 dbSNP
rs1176338471 3376 dbSNP
rs1379309916 3379 dbSNP
rs1439430363 3386 dbSNP
rs35322576 3396 dbSNP
rs1165957342 3402 dbSNP
rs1370681716 3404 dbSNP
rs1029306801 3407 dbSNP
rs1293001793 3410 dbSNP
rs1401047889 3415 dbSNP
rs78243190 3423 dbSNP
rs1329512266 3427 dbSNP
rs1376463554 3428 dbSNP
rs964142368 3436 dbSNP
rs1022005764 3439 dbSNP
rs1011070924 3441 dbSNP
rs371625196 3441 dbSNP
rs556202856 3441 dbSNP
rs886047659 3441 dbSNP
rs1258649186 3457 dbSNP
rs892334207 3458 dbSNP
rs1196244990 3460 dbSNP
rs1052256289 3463 dbSNP
rs576332364 3466 dbSNP
rs906426710 3468 dbSNP
rs186742619 3471 dbSNP
rs1182773542 3483 dbSNP
rs1258770879 3484 dbSNP
rs1422448039 3492 dbSNP
rs539074241 3497 dbSNP
rs368095812 3498 dbSNP
rs1467203820 3503 dbSNP
rs782272873 3506 dbSNP
rs782680780 3514 dbSNP
rs569799426 3519 dbSNP
rs1376629165 3520 dbSNP
rs1395247290 3522 dbSNP
rs1278721457 3544 dbSNP
rs1342317858 3547 dbSNP
rs1216231246 3552 dbSNP
rs1256916431 3570 dbSNP
rs1312406203 3583 dbSNP
rs1211725656 3590 dbSNP
rs915982015 3625 dbSNP
rs782181482 3628 dbSNP
rs1181660591 3638 dbSNP
rs183179797 3639 dbSNP
rs1479110176 3640 dbSNP
rs1191588212 3641 dbSNP
rs374231120 3653 dbSNP
rs941433119 3661 dbSNP
rs1415125206 3670 dbSNP
rs1178426376 3680 dbSNP
rs1357678166 3690 dbSNP
rs908738061 3693 dbSNP
rs1465320127 3698 dbSNP
rs982894546 3718 dbSNP
rs1298634502 3737 dbSNP
rs1362345836 3739 dbSNP
rs114397288 3750 dbSNP
rs922824136 3753 dbSNP
rs1367610853 3754 dbSNP
rs530143933 3757 dbSNP
rs192906840 3766 dbSNP
rs963786134 3776 dbSNP
rs1022372345 3788 dbSNP
rs1210571906 3793 dbSNP
rs989275964 3795 dbSNP
rs1489546799 3801 dbSNP
rs1215019096 3802 dbSNP
rs1242053259 3806 dbSNP
rs1478375681 3806 dbSNP
rs531768464 3807 dbSNP
rs782471793 3810 dbSNP
rs1432863283 3824 dbSNP
rs1159022280 3833 dbSNP
rs956642574 3842 dbSNP
rs1382003597 3846 dbSNP
rs781992363 3847 dbSNP
rs138637213 3856 dbSNP
rs1350421194 3861 dbSNP
rs1437957690 3868 dbSNP
rs1003351893 3870 dbSNP
rs1291324621 3890 dbSNP
rs1366461266 3894 dbSNP
rs906454418 3908 dbSNP
rs1311012205 3909 dbSNP
rs1356219116 3910 dbSNP
rs782031160 3917 dbSNP
rs1238472642 3919 dbSNP
rs1284126901 3924 dbSNP
rs1452745124 3929 dbSNP
rs1023516067 3936 dbSNP
rs549404480 3941 dbSNP
rs1245125513 3952 dbSNP
rs1012573216 3954 dbSNP
rs1382432212 3955 dbSNP
rs573760463 3955 dbSNP
rs1437536718 3957 dbSNP
rs527998458 3964 dbSNP
rs79900413 3965 dbSNP
rs1407076896 3989 dbSNP
rs1162070377 4002 dbSNP
rs1038762708 4005 dbSNP
rs1446895788 4006 dbSNP
rs941476872 4020 dbSNP
rs887169179 4025 dbSNP
rs1374229886 4032 dbSNP
rs1445001463 4036 dbSNP
rs781843680 4040 dbSNP
rs1279380227 4050 dbSNP
rs1357668535 4052 dbSNP
rs1230589840 4072 dbSNP
rs1047231969 4074 dbSNP
rs1334201228 4089 dbSNP
rs1199372841 4096 dbSNP
rs934121752 4102 dbSNP
rs1240235450 4109 dbSNP
rs1456640423 4124 dbSNP
rs782779955 4125 dbSNP
rs975672224 4126 dbSNP
rs942933762 4131 dbSNP
rs1473661082 4132 dbSNP
rs914936929 4133 dbSNP
rs567614820 4137 dbSNP
rs541035545 4141 dbSNP
rs1464841479 4177 dbSNP
rs1328587335 4179 dbSNP
rs956497051 4184 dbSNP
rs1450672749 4185 dbSNP
rs1282892332 4187 dbSNP
rs1355435342 4190 dbSNP
rs1219293125 4192 dbSNP
rs1260148288 4194 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucguacauGGGUGUCAc 5'
                  ::|||||| 
Target 5' --------UUCACAGUa 3'
 		1 - 9
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177623. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_4_1 PAR-CLIP data was present in ERX177627. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_4_5 PAR-CLIP data was present in ERX177599. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_2_1 PAR-CLIP data was present in ERX177603. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_2_5 PAR-CLIP data was present in ERX177611. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_3_1 PAR-CLIP data was present in ERX177615. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_3_5 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000531154.1 | 3UTR | UUCACAGUAGCUAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
60 hsa-miR-4318 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT068761 RB1 RB transcriptional corepressor 1 2 2
MIRT094193 THAP6 THAP domain containing 6 2 2
MIRT166771 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 2
MIRT185495 SRP9 signal recognition particle 9 2 2
MIRT347687 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT441948 PEX2 peroxisomal biogenesis factor 2 2 2
MIRT443293 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT447126 DUSP16 dual specificity phosphatase 16 2 2
MIRT447428 MED21 mediator complex subunit 21 2 2
MIRT447971 MSH6 mutS homolog 6 2 2
MIRT450693 RPN2 ribophorin II 2 2
MIRT465671 TNPO2 transportin 2 2 2
MIRT477011 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT479898 CCDC117 coiled-coil domain containing 117 2 2
MIRT488681 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT490349 PEX10 peroxisomal biogenesis factor 10 2 2
MIRT491108 NARS asparaginyl-tRNA synthetase 2 2
MIRT494804 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT512730 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT518098 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 4
MIRT518113 RPS7 ribosomal protein S7 2 2
MIRT528967 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 2 2
MIRT529796 AP4S1 adaptor related protein complex 4 sigma 1 subunit 2 2
MIRT530503 FADS6 fatty acid desaturase 6 2 2
MIRT530797 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT532654 TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 2 2
MIRT533417 TXLNG taxilin gamma 2 2
MIRT536327 LGSN lengsin, lens protein with glutamine synthetase domain 2 2
MIRT537611 ERMP1 endoplasmic reticulum metallopeptidase 1 2 2
MIRT540738 FN3KRP fructosamine 3 kinase related protein 2 2
MIRT545780 ZNF805 zinc finger protein 805 2 2
MIRT549884 GINS4 GINS complex subunit 4 2 2
MIRT550618 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT551451 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT554858 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT556558 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT572893 ADCY2 adenylate cyclase 2 2 2
MIRT576517 Slc35e2 solute carrier family 35, member E2 2 2
MIRT609005 PYGO1 pygopus family PHD finger 1 2 2
MIRT614782 SEC63 SEC63 homolog, protein translocation regulator 2 2
MIRT633849 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2 2
MIRT634841 APOOL apolipoprotein O like 2 2
MIRT638838 CRTAP cartilage associated protein 2 2
MIRT639980 POU5F1B POU class 5 homeobox 1B 2 2
MIRT640263 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT641538 SNW1 SNW domain containing 1 2 2
MIRT656540 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT667590 LONRF2 LON peptidase N-terminal domain and ring finger 2 2 2
MIRT667732 KIAA1456 KIAA1456 2 2
MIRT667911 ING1 inhibitor of growth family member 1 2 2
MIRT669865 BROX BRO1 domain and CAAX motif containing 2 4
MIRT675877 ATP1B4 ATPase Na+/K+ transporting family member beta 4 2 2
MIRT676868 ZNF451 zinc finger protein 451 2 2
MIRT683211 MBNL1 muscleblind like splicing regulator 1 2 2
MIRT704515 COL4A1 collagen type IV alpha 1 chain 2 2
MIRT710184 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT712036 TRIP13 thyroid hormone receptor interactor 13 2 2
MIRT716586 BRAP BRCA1 associated protein 2 2
MIRT724189 MMP16 matrix metallopeptidase 16 2 2
MIRT724205 MED7 mediator complex subunit 7 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4318 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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