miRTarBase - #MIRT495087


—
pre-miRNA Information
pre-miRNA hsa-mir-4690   
Genomic Coordinates chr11: 65636310 - 65636369
Description Homo sapiens miR-4690 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4690-5p
Sequence 1| GAGCAGGCGAGGCUGGGCUGAA |22
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM5426974 4 COSMIC
COSM7294383 4 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs762767645 3 dbSNP
rs1158020577 4 dbSNP
rs1031810148 7 dbSNP
rs763979181 8 dbSNP
rs751083148 11 dbSNP
rs1338601494 12 dbSNP
rs1403894228 14 dbSNP
rs541332946 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol IGSF3   
Synonyms EWI-3, LCDD, V8
Description immunoglobulin superfamily member 3
Transcript NM_001007237   
Other Transcripts NM_001542   
Expression
Putative miRNA Targets on IGSF3
3'UTR of IGSF3
(miRNA target sites are highlighted)		 
>IGSF3|NM_001007237|3'UTR
   1 GCGGGTGATGCCCCAGCGGATGTTGGCCACGGAGGAGCTGAGGCTCTCCCTTTCTCTGTGATTGGACAGTTGACAGCACC
  81 CAAACTCTGGGGTGCATGTGTGTGGAAAGTTGTCAGACTTGAAAAGTGTTCCAAGTTCCCAGTCAGTCACAGAGACAGAC
 161 TGCCTCTCGGTGGCAGTCTTGGTTGGTTAGCTATTTGCGCGCAAATGTTGTGATCCTGCCATTATAGATTTCTTGTTTCT
 241 GTTTTTAGTAATGTAGTGAGTAGCTCCAGGTGCCACATCTACTCACAGATTTATCTAGTATTCTCAGATAGATGTTACAG
 321 GGCTTCTTATTCTTTGTAATGTACTCTTTTTAAATCCCTTTAGTTTACCCTTTTTGGATTCCTTAATGTGGACGAATTTC
 401 TCTTACGTACAACTGACAGCAAAAGGAAGGGCGAACTTTCTAGTGACAAGGAATCTCTTCCAAGACTTTGTTTTTGCACA
 481 TTTGAAAATGCCACCCATGGATCAAAATATACCCAAACGTTTTTTACTTTCTTAACAAGACTTAAGAATTGTGTGTAGTG
 561 TGGGCAAAATTTGTATGTTGTCTTTTCCCTCAGCTGGAGTTATTGGAACCACTTTGTAGTCAAGACGAAAGCACTGAATT
 641 TTGCTTCAAAGAACTGTGTATGTACAAGAGAAATCCTGCATAACCCCATTAGGAGTAGATGGTGCCCGGCCTATCTGTCA
 721 GGGAGGCAAAAAAGGCTTCATCCCATCCTTGCCAAAAAATAAGAAAACTGTCTTGGAGAATGGGTCAGAAGCCCCAAACG
 801 GCACACACTTTCCAAATTAAAGTGGGCAGGGGCTGCTTTTAGCAGCTGCTGACCTGCAGATTTGTCAAAGCCAGTGACTA
 881 GAGAAGGAAGGGAGAAAGGCTGGCTGTTGGCTTGCTCTGAGCTGCAAGGATGGTCTCTAACTGATTAACTGTGAGCAGGT
 961 GGGCCTGTGTCTTCAGGTGCTTTGCCAAACTCTTAAAAGAAAGTGTCCAGTGAACTTGGAAGTGGGCCCCTGAGCTGAGC
1041 ACAGGGCCAAAGCAGCCATGGCAGACACCTGACGGAGGGCACGGGGCTGGCTGACACTAAGTTTGGTGGGACAGTGAGGG
1121 GTGGGAGGGGGGTTTCCAGGGCCTGGTGTTGGAGAGTGCAGAGAAATATCTACCTCCCTGGAGGTGTGAAGACTAGGTTT
1201 TTCTTCTTCCTTCCAATTAGATTTTCCTTAATTATAGTGATGTCTTCCTTATTCATTTTTCTCTCCCTGCCTCTCACTGC
1281 CATAAGAATATCAGCCTGGGGGCAGTCCAGACGCAGCCCTTTGTCATCCTTTCTGTTTGCCTAGTCTCAGCAGACTGTGA
1361 TCACAAGGCATTGTCTGTGGGATTTTTCCTTTCCCTTTCTTGATCTCTCTTGTGGTTCTAGGTTGTTTGGTTGTTCATTG
1441 TTATGGTGGCTTTTTATTTTAACGCCCCTTGAGCCCCATGATGGCTGGTGTCACCCTGTTCTTTTACACTGTTGGGCCAG
1521 GTGCTGCTTGTCCTTCTTAGGGCATCATCAATTGCAAATATTTCCTTTTGCTCCCTTTATGAAGATGTTCTTATACCCTT
1601 GCTTTCCCATATTTTTCTGGCCAAGCATGCCATCTCCTTTACTCTGGGAACTTACATCCTGAATCCCAAGAGGGGGTCAC
1681 AGTTTGGAAAAAGTCATCAGGGATTCTGGAACTAAGTCTGATAAAAGATTCCAGTGAAGCCCTGTTCTGAGAACGAGCAG
1761 ACTGCAGGGGAGGCCATGGGATTCCCCAGGCCAGTGTCTGTGCTGATCCTTCAAGGGTCTGCAGGTATGCAGGTGGCCTG
1841 GGCTGCTCGGCAGATACTTTGCTGATTCCCAGCTGAGGGGAGCATGGTGGCGATTGCTCAGCCATTTTCTGACAGACACA
1921 CAGACCTGCCTTTTCTCCCCCAAGTATACCGTACCCTCCTGTGAGACAGTGTGTGCAGGCACCACCACCTTAATCCTGCT
2001 GTTGCCTGACATGCTGATTCTCATTTATTATGCTGCATCAACACATTAGAGGTACAGGAGCGGCTCAGTCATGAAAAAAG
2081 AAGGTCTTTTGCCCCATTTCTTTATTTCAGAGATGTGGGCTTTCAGTGGGAATTTGCTGACTCCTACTTTATAGGCTGAG
2161 TCAATGAGGGAAGATGACTGGCGTTTCCTCTGTCTAAATGGGAGGTTGCCAGAGCGCTGGCTGGGACTAGGATGTGTAAC
2241 TAAGATTTCAGTTTGAAATCTTAGATTTCAGTTCACGGCGATAAAGAAGTAGGTGCTGCACACAAATATGTAAAGCAATT
2321 GTAGGAAATTTGAAAGGAAAAAAAGAAACCGAAGCCAGTATTTTAATAATTGCTTTTTCTGTGTATTTTGTATTGGGCTG
2401 GGGGATAGCATCAAAGGTTGAACTTTTTGAGCTTTCTATGAAAAACCCCAGGACCTTCTTTCTTTGGCCATTTCTATGGA
2481 AATGCGATGTCAGATGGATGGTAATGGTGCCCTCCAGTGGCTGTGAGACCTCATTGCGCATTGTCTACTGGAGCTTTAGT
2561 CTTCTGAGACGGAGGAAAACTGCTGAATACTCTGGATTCATCTATGTCTACAATGTTGCATTTATGAAAAACTACACTGT
2641 GCTAGGCGCATTCTAGGACATGAATATGACCACACCCTCTTTCACCGGGTGTTTCTGTAGCAAGTTTTCATATTCTTTTC
2721 AAACAATGGTTTCTCTGCGTTAATTATTGAGGAAAAAAAAAGATGGGGTAAGAAAACTACCCATGCATGATGTAGAGAGC
2801 TGTTGATTTGTTTCTGTTTTTTTAAAGGAAAACTATTTGTAAGATGTTGCACTAAAACATTTTATATACACTTCAGAGAC
2881 CTGTAGTAAATTATGTTGAAAATACGGCTGTTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aagUCGGGUCG--GAGCGGACGAg 5'
             || |::||  :| ||:|||| 
Target 5' gaaAGGCTGGCTGTTGGCTTGCTc 3'
 894 - 917 141.00 -19.60
2 
miRNA  3' aaGUCGGGUCGGAGCGGACGAg 5'
            |||  ::|||| | ||||| 
Target 5' tgCAG-GTGGCCTGGGCTGCTc 3'
 1828 - 1848 131.00 -22.50
3 
miRNA  3' aaGUCG-GGUCGGAG--CGGACGAg 5'
            || | ||| |||:   |||||| 
Target 5' ggCACCACCA-CCTTAATCCTGCTg 3'
 1978 - 2001 125.00 -15.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30463736 3 COSMIC
COSN30498601 12 COSMIC
COSN13458507 18 COSMIC
COSN31483648 29 COSMIC
COSN30502895 30 COSMIC
COSN15668327 169 COSMIC
COSN32036810 227 COSMIC
COSN31571777 376 COSMIC
COSN19063796 410 COSMIC
COSN26583935 549 COSMIC
COSN31557567 619 COSMIC
COSN31568259 627 COSMIC
COSN5197276 704 COSMIC
COSN31531993 847 COSMIC
COSN1402817 1074 COSMIC
COSN28779606 1176 COSMIC
COSN1087644 1718 COSMIC
COSN23756917 1808 COSMIC
COSN31480827 1892 COSMIC
COSN31516548 2020 COSMIC
COSN31595818 2322 COSMIC
COSN31571779 2362 COSMIC
COSN22527080 2436 COSMIC
COSN31584471 2474 COSMIC
COSN31533894 2551 COSMIC
COSN7173510 2604 COSMIC
COSN31584665 2715 COSMIC
COSN31522739 2731 COSMIC
COSN31582917 2733 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs757425283 2 dbSNP
rs1483936380 3 dbSNP
rs751866372 5 dbSNP
rs1209350188 9 dbSNP
rs368090207 13 dbSNP
rs1310377003 14 dbSNP
rs776499230 17 dbSNP
rs375604819 18 dbSNP
rs371089553 19 dbSNP
rs760186386 21 dbSNP
rs1377347589 22 dbSNP
rs377496042 30 dbSNP
rs767135912 31 dbSNP
rs1462200005 33 dbSNP
rs1360952577 35 dbSNP
rs1168546931 37 dbSNP
rs761612038 39 dbSNP
rs1451321232 46 dbSNP
rs1371633862 49 dbSNP
rs1336417740 62 dbSNP
rs1001334907 96 dbSNP
rs564932576 99 dbSNP
rs1468811980 100 dbSNP
rs1334057957 106 dbSNP
rs1431523058 108 dbSNP
rs543745474 114 dbSNP
rs1005645674 137 dbSNP
rs1050291220 139 dbSNP
rs531895439 151 dbSNP
rs1414757675 162 dbSNP
rs1235232079 168 dbSNP
rs1426842745 169 dbSNP
rs780752484 169 dbSNP
rs1256782786 190 dbSNP
rs116610628 193 dbSNP
rs147191278 197 dbSNP
rs989548362 198 dbSNP
rs143770903 199 dbSNP
rs183177627 200 dbSNP
rs115715850 201 dbSNP
rs112239212 207 dbSNP
rs757293195 213 dbSNP
rs971008130 225 dbSNP
rs753951073 230 dbSNP
rs1314299150 234 dbSNP
rs764758957 236 dbSNP
rs1047078668 243 dbSNP
rs756669425 258 dbSNP
rs753212562 262 dbSNP
rs952879126 267 dbSNP
rs1041288403 269 dbSNP
rs1288216908 270 dbSNP
rs577761233 276 dbSNP
rs768012732 278 dbSNP
rs1027401397 284 dbSNP
rs192918280 289 dbSNP
rs897460000 300 dbSNP
rs1221843759 305 dbSNP
rs1014593739 308 dbSNP
rs1009206117 310 dbSNP
rs1215203397 311 dbSNP
rs1259463627 319 dbSNP
rs116356405 323 dbSNP
rs1210987989 335 dbSNP
rs1267026764 341 dbSNP
rs1412968214 343 dbSNP
rs1050800595 344 dbSNP
rs931816081 345 dbSNP
rs187417115 349 dbSNP
rs1043186747 358 dbSNP
rs1053791522 371 dbSNP
rs1312136665 376 dbSNP
rs1448556227 377 dbSNP
rs1360652189 378 dbSNP
rs1156554858 381 dbSNP
rs1399777626 382 dbSNP
rs1412202100 385 dbSNP
rs1160753755 386 dbSNP
rs1473907755 388 dbSNP
rs947181102 393 dbSNP
rs563506572 394 dbSNP
rs555550577 402 dbSNP
rs988531995 406 dbSNP
rs533705320 407 dbSNP
rs764938026 412 dbSNP
rs765690188 414 dbSNP
rs1215453755 421 dbSNP
rs1217998168 428 dbSNP
rs1465538605 432 dbSNP
rs1304911923 433 dbSNP
rs34860706 434 dbSNP
rs980035551 439 dbSNP
rs566166399 442 dbSNP
rs1323582082 445 dbSNP
rs969848984 447 dbSNP
rs1291759468 449 dbSNP
rs139748484 451 dbSNP
rs1016125856 453 dbSNP
rs1334234082 456 dbSNP
rs761286425 461 dbSNP
rs1228795974 463 dbSNP
rs952863372 465 dbSNP
rs117510788 469 dbSNP
rs144457527 471 dbSNP
rs1165382323 477 dbSNP
rs1429686001 481 dbSNP
rs549742858 497 dbSNP
rs149250961 498 dbSNP
rs879172907 500 dbSNP
rs994095230 510 dbSNP
rs1388940462 514 dbSNP
rs1370972425 519 dbSNP
rs901184008 521 dbSNP
rs1027161853 523 dbSNP
rs973108858 526 dbSNP
rs1322126037 536 dbSNP
rs1459479149 539 dbSNP
rs561388798 551 dbSNP
rs1019799570 555 dbSNP
rs543215487 557 dbSNP
rs1231291196 564 dbSNP
rs889934819 566 dbSNP
rs776095233 573 dbSNP
rs1426096657 576 dbSNP
rs1014975478 577 dbSNP
rs1230881076 587 dbSNP
rs1008549644 589 dbSNP
rs890141619 603 dbSNP
rs1043269666 610 dbSNP
rs1442656980 626 dbSNP
rs947117611 627 dbSNP
rs1212051668 635 dbSNP
rs1168591525 649 dbSNP
rs1361155886 655 dbSNP
rs1466599413 660 dbSNP
rs891512801 674 dbSNP
rs527836767 678 dbSNP
rs1437820371 680 dbSNP
rs138362793 681 dbSNP
rs1053555216 684 dbSNP
rs935397169 686 dbSNP
rs902620296 691 dbSNP
rs761385833 692 dbSNP
rs1313533692 700 dbSNP
rs1203936915 704 dbSNP
rs768617809 707 dbSNP
rs77837043 708 dbSNP
rs948639981 710 dbSNP
rs1242696643 713 dbSNP
rs949409091 717 dbSNP
rs555644489 725 dbSNP
rs991051274 734 dbSNP
rs1365662184 742 dbSNP
rs984675551 743 dbSNP
rs1480865292 759 dbSNP
rs1175989638 760 dbSNP
rs1403928619 769 dbSNP
rs1458939913 781 dbSNP
rs1321804720 791 dbSNP
rs769879569 792 dbSNP
rs1429263827 795 dbSNP
rs1276933080 796 dbSNP
rs1299412016 797 dbSNP
rs950615356 799 dbSNP
rs775359228 800 dbSNP
rs150115067 808 dbSNP
rs1293635633 811 dbSNP
rs972908486 813 dbSNP
rs1284839032 814 dbSNP
rs1458932778 818 dbSNP
rs961566208 826 dbSNP
rs907599112 829 dbSNP
rs1490456115 830 dbSNP
rs1198954936 831 dbSNP
rs1427551319 831 dbSNP
rs1170343142 833 dbSNP
rs1473597643 834 dbSNP
rs1159168698 850 dbSNP
rs556226819 856 dbSNP
rs965337176 859 dbSNP
rs370114927 860 dbSNP
rs1404795304 864 dbSNP
rs1302109785 870 dbSNP
rs1343305424 871 dbSNP
rs996011829 883 dbSNP
rs1279594061 892 dbSNP
rs957967819 892 dbSNP
rs1192090312 903 dbSNP
rs1292018214 921 dbSNP
rs1490452145 932 dbSNP
rs1007093962 933 dbSNP
rs1221524112 936 dbSNP
rs1267015153 942 dbSNP
rs1484134730 946 dbSNP
rs747897194 949 dbSNP
rs890078826 958 dbSNP
rs142453002 963 dbSNP
rs1268238287 971 dbSNP
rs138983885 973 dbSNP
rs183084669 986 dbSNP
rs1424397755 988 dbSNP
rs1046466081 999 dbSNP
rs760947369 1003 dbSNP
rs1014093272 1023 dbSNP
rs769767207 1031 dbSNP
rs773240545 1044 dbSNP
rs1276533299 1061 dbSNP
rs72697339 1073 dbSNP
rs190965269 1074 dbSNP
rs538775096 1082 dbSNP
rs1037310349 1084 dbSNP
rs1044121421 1086 dbSNP
rs1344053520 1088 dbSNP
rs1342578979 1089 dbSNP
rs1196586461 1090 dbSNP
rs1370532773 1094 dbSNP
rs542446951 1096 dbSNP
rs1189764991 1105 dbSNP
rs777972334 1105 dbSNP
rs577426762 1106 dbSNP
rs912757861 1114 dbSNP
rs76203894 1118 dbSNP
rs376687529 1124 dbSNP
rs1172170677 1125 dbSNP
rs531567043 1130 dbSNP
rs929130337 1131 dbSNP
rs919096398 1132 dbSNP
rs754403026 1133 dbSNP
rs974394838 1133 dbSNP
rs972775061 1137 dbSNP
rs567952658 1138 dbSNP
rs1032204754 1141 dbSNP
rs999430028 1142 dbSNP
rs1382890463 1148 dbSNP
rs1178504574 1161 dbSNP
rs1451752389 1163 dbSNP
rs966532946 1167 dbSNP
rs1249887907 1169 dbSNP
rs1025229416 1171 dbSNP
rs965474048 1172 dbSNP
rs912556241 1176 dbSNP
rs985393201 1177 dbSNP
rs954190498 1178 dbSNP
rs28438614 1179 dbSNP
rs1263764069 1190 dbSNP
rs1483357670 1196 dbSNP
rs1055243486 1204 dbSNP
rs995488386 1206 dbSNP
rs1429455917 1216 dbSNP
rs1192984568 1226 dbSNP
rs549459376 1235 dbSNP
rs1253799293 1241 dbSNP
rs1371726228 1249 dbSNP
rs1208480877 1251 dbSNP
rs1178156125 1252 dbSNP
rs1406151459 1259 dbSNP
rs898537457 1271 dbSNP
rs1012257113 1275 dbSNP
rs753267547 1282 dbSNP
rs1234922601 1283 dbSNP
rs1334569973 1290 dbSNP
rs868468329 1293 dbSNP
rs1037279278 1299 dbSNP
rs141455031 1300 dbSNP
rs186521209 1312 dbSNP
rs182279398 1313 dbSNP
rs1002620031 1314 dbSNP
rs906983373 1316 dbSNP
rs551984842 1317 dbSNP
rs1221809669 1322 dbSNP
rs1262998330 1329 dbSNP
rs1311581605 1330 dbSNP
rs1395881910 1335 dbSNP
rs1486453643 1349 dbSNP
rs1205094280 1356 dbSNP
rs1403324194 1361 dbSNP
rs543731183 1368 dbSNP
rs768065824 1372 dbSNP
rs1201125252 1373 dbSNP
rs45496501 1376 dbSNP
rs1479811382 1381 dbSNP
rs544195500 1386 dbSNP
rs1173567030 1394 dbSNP
rs11553410 1405 dbSNP
rs1365062476 1411 dbSNP
rs974491034 1417 dbSNP
rs1296880465 1419 dbSNP
rs1288232776 1428 dbSNP
rs1382495478 1432 dbSNP
rs1406615335 1437 dbSNP
rs1303952770 1441 dbSNP
rs1345172598 1444 dbSNP
rs929239099 1448 dbSNP
rs1309190406 1463 dbSNP
rs919095703 1464 dbSNP
rs751938630 1467 dbSNP
rs1259548699 1478 dbSNP
rs944551080 1481 dbSNP
rs1361995291 1487 dbSNP
rs1411455499 1490 dbSNP
rs1223752111 1507 dbSNP
rs148172272 1510 dbSNP
rs1268653586 1512 dbSNP
rs1490072434 1515 dbSNP
rs12126480 1520 dbSNP
rs1160002151 1526 dbSNP
rs1251978477 1530 dbSNP
rs912610185 1534 dbSNP
rs561712341 1537 dbSNP
rs1473578946 1539 dbSNP
rs12126479 1540 dbSNP
rs1158284374 1547 dbSNP
rs1362032554 1551 dbSNP
rs985530421 1551 dbSNP
rs954044149 1553 dbSNP
rs1024778731 1559 dbSNP
rs992387510 1565 dbSNP
rs959258127 1571 dbSNP
rs1185703633 1575 dbSNP
rs764845640 1595 dbSNP
rs1390929747 1597 dbSNP
rs914586824 1607 dbSNP
rs1305458798 1617 dbSNP
rs990396919 1626 dbSNP
rs1385551912 1627 dbSNP
rs867941217 1634 dbSNP
rs143798556 1639 dbSNP
rs1357755574 1641 dbSNP
rs1218913059 1642 dbSNP
rs572779096 1646 dbSNP
rs1252773102 1655 dbSNP
rs1480655864 1671 dbSNP
rs995624329 1672 dbSNP
rs761494101 1675 dbSNP
rs1446333057 1694 dbSNP
rs1184140355 1705 dbSNP
rs1384318979 1706 dbSNP
rs1422584262 1714 dbSNP
rs1484691980 1724 dbSNP
rs753447483 1730 dbSNP
rs898465468 1734 dbSNP
rs1267035541 1744 dbSNP
rs1003005101 1751 dbSNP
rs971558339 1754 dbSNP
rs186109930 1755 dbSNP
rs891387156 1764 dbSNP
rs768684679 1770 dbSNP
rs1216730042 1782 dbSNP
rs900052422 1785 dbSNP
rs1307672969 1786 dbSNP
rs1244677965 1793 dbSNP
rs1255530136 1794 dbSNP
rs770890236 1795 dbSNP
rs760120407 1801 dbSNP
rs1380816717 1803 dbSNP
rs539212337 1804 dbSNP
rs1321448953 1808 dbSNP
rs577725429 1809 dbSNP
rs897712960 1836 dbSNP
rs1408369728 1838 dbSNP
rs1040270429 1843 dbSNP
rs772046750 1849 dbSNP
rs1161440553 1856 dbSNP
rs1433528927 1862 dbSNP
rs1289781133 1870 dbSNP
rs1361709150 1878 dbSNP
rs556335923 1884 dbSNP
rs1368917164 1891 dbSNP
rs538335786 1892 dbSNP
rs181117247 1893 dbSNP
rs1049789550 1910 dbSNP
rs1247103027 1914 dbSNP
rs549345860 1915 dbSNP
rs932754341 1919 dbSNP
rs974119440 1919 dbSNP
rs962799925 1923 dbSNP
rs1431772448 1925 dbSNP
rs1480792325 1937 dbSNP
rs1270755626 1940 dbSNP
rs1423196130 1946 dbSNP
rs914574663 1949 dbSNP
rs990588904 1950 dbSNP
rs148930700 1951 dbSNP
rs1357672303 1955 dbSNP
rs1429106989 1958 dbSNP
rs1295936036 1961 dbSNP
rs924815441 1967 dbSNP
rs1286408806 1970 dbSNP
rs1225767082 1972 dbSNP
rs567145841 1980 dbSNP
rs981708550 1983 dbSNP
rs774176743 1985 dbSNP
rs552021606 1989 dbSNP
rs1023166498 1995 dbSNP
rs1316086947 2005 dbSNP
rs1030317043 2025 dbSNP
rs1270811071 2026 dbSNP
rs533516115 2043 dbSNP
rs546068165 2045 dbSNP
rs997144209 2047 dbSNP
rs1322979256 2049 dbSNP
rs899978899 2055 dbSNP
rs991252423 2056 dbSNP
rs1471235018 2060 dbSNP
rs563067649 2061 dbSNP
rs550442829 2062 dbSNP
rs1407950413 2064 dbSNP
rs771102086 2076 dbSNP
rs1165815235 2078 dbSNP
rs1366586372 2079 dbSNP
rs1027414946 2080 dbSNP
rs1424837979 2080 dbSNP
rs936403002 2084 dbSNP
rs749544974 2096 dbSNP
rs903596330 2105 dbSNP
rs1372468976 2117 dbSNP
rs1237913077 2125 dbSNP
rs566701368 2158 dbSNP
rs897516947 2168 dbSNP
rs1042169228 2170 dbSNP
rs1359908822 2180 dbSNP
rs1222012319 2183 dbSNP
rs528965870 2186 dbSNP
rs547895083 2190 dbSNP
rs1018791909 2204 dbSNP
rs561555963 2208 dbSNP
rs532616265 2210 dbSNP
rs540197506 2221 dbSNP
rs1438308059 2222 dbSNP
rs888931829 2240 dbSNP
rs1386233905 2251 dbSNP
rs1444479999 2252 dbSNP
rs917630498 2254 dbSNP
rs1388194261 2255 dbSNP
rs1050724586 2263 dbSNP
rs1188917075 2264 dbSNP
rs1411323249 2275 dbSNP
rs572816178 2276 dbSNP
rs372806342 2277 dbSNP
rs932742547 2279 dbSNP
rs577947800 2280 dbSNP
rs1317149482 2282 dbSNP
rs572247961 2288 dbSNP
rs558414863 2293 dbSNP
rs1292722833 2295 dbSNP
rs926414841 2298 dbSNP
rs1341681907 2299 dbSNP
rs1196604293 2300 dbSNP
rs934624112 2305 dbSNP
rs1456545140 2309 dbSNP
rs74111632 2310 dbSNP
rs1206117987 2314 dbSNP
rs748230794 2319 dbSNP
rs1444374522 2321 dbSNP
rs1341956952 2322 dbSNP
rs1185807391 2333 dbSNP
rs575143464 2337 dbSNP
rs973919795 2340 dbSNP
rs189943280 2343 dbSNP
rs962558350 2345 dbSNP
rs1168153338 2349 dbSNP
rs1230985986 2350 dbSNP
rs1463670016 2351 dbSNP
rs1338593233 2353 dbSNP
rs537991314 2365 dbSNP
rs982918861 2370 dbSNP
rs1274474409 2378 dbSNP
rs955551409 2379 dbSNP
rs1029674616 2387 dbSNP
rs1228411299 2390 dbSNP
rs1277877089 2393 dbSNP
rs574060172 2395 dbSNP
rs997480762 2396 dbSNP
rs1225482235 2405 dbSNP
rs1319552307 2438 dbSNP
rs1332877980 2439 dbSNP
rs144772515 2441 dbSNP
rs534152116 2445 dbSNP
rs1264233858 2450 dbSNP
rs992034403 2454 dbSNP
rs768694765 2461 dbSNP
rs1262076280 2462 dbSNP
rs1476544470 2465 dbSNP
rs1177913406 2468 dbSNP
rs781778929 2474 dbSNP
rs1465431176 2476 dbSNP
rs1000308253 2481 dbSNP
rs903397084 2485 dbSNP
rs1168990169 2486 dbSNP
rs1431345390 2496 dbSNP
rs1395999208 2499 dbSNP
rs1027794793 2500 dbSNP
rs1297796685 2502 dbSNP
rs971855115 2505 dbSNP
rs1171638702 2523 dbSNP
rs200983976 2524 dbSNP
rs1478094000 2528 dbSNP
rs1283934283 2529 dbSNP
rs961677420 2529 dbSNP
rs1311695092 2535 dbSNP
rs1247926383 2537 dbSNP
rs1018590100 2538 dbSNP
rs896106242 2555 dbSNP
rs1056145937 2557 dbSNP
rs1201147798 2559 dbSNP
rs1008767663 2561 dbSNP
rs1432158084 2564 dbSNP
rs889063920 2570 dbSNP
rs1207810232 2571 dbSNP
rs868442089 2582 dbSNP
rs937886848 2584 dbSNP
rs1028916218 2595 dbSNP
rs1220008983 2596 dbSNP
rs1347331640 2599 dbSNP
rs1157785822 2601 dbSNP
rs758692087 2604 dbSNP
rs893656223 2605 dbSNP
rs755488783 2613 dbSNP
rs1304044831 2615 dbSNP
rs1385202749 2623 dbSNP
rs1434881952 2638 dbSNP
rs1309764339 2639 dbSNP
rs554069982 2648 dbSNP
rs1240058805 2655 dbSNP
rs1284245645 2655 dbSNP
rs1362107950 2664 dbSNP
rs1224243173 2674 dbSNP
rs1265701901 2675 dbSNP
rs11553409 2676 dbSNP
rs1207502083 2677 dbSNP
rs1252088368 2678 dbSNP
rs1419534214 2684 dbSNP
rs998968462 2686 dbSNP
rs1357183746 2687 dbSNP
rs1378238778 2692 dbSNP
rs1446294109 2693 dbSNP
rs941164190 2726 dbSNP
rs535400642 2727 dbSNP
rs903165683 2727 dbSNP
rs1299889554 2728 dbSNP
rs908408664 2733 dbSNP
rs1414707124 2735 dbSNP
rs1307797804 2737 dbSNP
rs983230049 2738 dbSNP
rs1045795971 2739 dbSNP
rs1320698138 2745 dbSNP
rs567171613 2747 dbSNP
rs1471970295 2748 dbSNP
rs1413429765 2749 dbSNP
rs1184928728 2751 dbSNP
rs1482508260 2752 dbSNP
rs1242167265 2753 dbSNP
rs1252495787 2762 dbSNP
rs955499287 2762 dbSNP
rs1197932562 2781 dbSNP
rs1211209846 2784 dbSNP
rs568315414 2787 dbSNP
rs950041060 2790 dbSNP
rs538298498 2797 dbSNP
rs1266412100 2823 dbSNP
rs201510658 2824 dbSNP
rs1412845087 2832 dbSNP
rs1422220252 2837 dbSNP
rs1172878345 2846 dbSNP
rs1329931419 2866 dbSNP
rs142424788 2872 dbSNP
rs1329878095 2880 dbSNP
rs1408875931 2881 dbSNP
rs373716445 2884 dbSNP
rs1056069891 2894 dbSNP
rs185738553 2905 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC-D2
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1133252. RNA binding protein: AGO2. Condition:Untreated ...

- Majoros WH; Lekprasert P; Mukherjee N; et al., 2013, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aagucgggucgGAGCGGACGAg 5'
                     :| ||||||| 
Target 5' -----------UUGGCCUGCUa 3'
 		1 - 11
Article - Majoros WH; Lekprasert P; Mukherjee N; et al.
- Nature methods, 2013
High-throughput sequencing has opened numerous possibilities for the identification of regulatory RNA-binding events. Cross-linking and immunoprecipitation of Argonaute proteins can pinpoint a microRNA (miRNA) target site within tens of bases but leaves the identity of the miRNA unresolved. A flexible computational framework, microMUMMIE, integrates sequence with cross-linking features and reliably identifies the miRNA family involved in each binding event. It considerably outperforms sequence-only approaches and quantifies the prevalence of noncanonical binding modes.
LinkOut: [PMID: 23708386]
CLIP-seq Support 1 for dataset GSM1133252
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC-D2 / Untreated
Location of target site ENST00000369486.3 | 3UTR | UUGGCCUGCUAGGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23708386 / GSE46611
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
42 hsa-miR-4690-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071223 FCF1 FCF1, rRNA-processing protein 2 2
MIRT082025 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT144286 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT202048 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT213227 REST RE1 silencing transcription factor 2 6
MIRT445866 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT455955 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT459110 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT460327 SH3RF1 SH3 domain containing ring finger 1 2 2
MIRT461645 ZSWIM4 zinc finger SWIM-type containing 4 2 2
MIRT463497 ZC3H10 zinc finger CCCH-type containing 10 2 2
MIRT464900 UBALD1 UBA like domain containing 1 2 2
MIRT472262 NFIC nuclear factor I C 2 2
MIRT478028 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT483753 ALDH9A1 aldehyde dehydrogenase 9 family member A1 2 2
MIRT485186 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 4
MIRT486550 DCTN4 dynactin subunit 4 2 2
MIRT495087 IGSF3 immunoglobulin superfamily member 3 2 2
MIRT495141 ZNRF1 zinc and ring finger 1 2 2
MIRT501269 NHS NHS actin remodeling regulator 2 4
MIRT503264 KIF18B kinesin family member 18B 2 2
MIRT507165 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT512519 BTBD19 BTB domain containing 19 2 2
MIRT528862 PKP1 plakophilin 1 2 2
MIRT546526 SERTAD3 SERTA domain containing 3 2 2
MIRT555058 PYURF PIGY upstream reading frame 2 2
MIRT574028 RIMBP3C RIMS binding protein 3C 2 2
MIRT574106 VASN vasorin 2 2
MIRT630923 UNC93A unc-93 homolog A 2 2
MIRT640178 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT655959 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT659747 CCDC30 coiled-coil domain containing 30 2 2
MIRT666062 STK40 serine/threonine kinase 40 2 2
MIRT670696 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 4
MIRT674196 GJD3 gap junction protein delta 3 2 2
MIRT686948 SFT2D3 SFT2 domain containing 3 2 2
MIRT697466 ZC3H4 zinc finger CCCH-type containing 4 2 2
MIRT698221 TMEM248 transmembrane protein 248 2 2
MIRT699448 SLC1A5 solute carrier family 1 member 5 2 2
MIRT718999 UTP15 UTP15, small subunit processome component 2 2
MIRT720024 TFAP2C transcription factor AP-2 gamma 2 2
MIRT721530 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4690 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-4690-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4690-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4690-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4690-5p Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4690-5p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4690-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4690-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4690-5p Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-4690-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4690-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-4690-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4690-5p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4690-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4690-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4690-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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