miRTarBase - #MIRT495209


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pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-5p
Sequence 16| UAAAUCCCAUGGUGCCUUCUCCU |38
Evidence Experimental
Experiments SAGE
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 10 + 51299590 29233923, 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs113212828 2 dbSNP
rs1265154909 7 dbSNP
rs76759855 9 dbSNP
rs1032735304 10 dbSNP
rs1318073696 10 dbSNP
rs1486056689 11 dbSNP
rs1225930966 12 dbSNP
rs1011066926 14 dbSNP
rs1261327694 19 dbSNP
rs1020985018 22 dbSNP
rs1426923077 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol EDN3   
Synonyms ET-3, ET3, HSCR4, PPET3, WS4B
Description endothelin 3
Transcript NM_207032   
Other Transcripts NM_207033 , NM_207034   
Expression
Putative miRNA Targets on EDN3
3'UTR of EDN3
(miRNA target sites are highlighted)		 
>EDN3|NM_207032|3'UTR
   1 ACCTCCACCATCCAAAGCTCATGCCCGGCAGTGGACTCGCCCTCGCTCCATCTACCTGCCCCCGCTGCCTCTTTCAGGAA
  81 GGAGCCCCTTAGGAGGACAGGCCTGCAGCATCCTGGTCTCGGGAGGCTTCTGTCATTGCTCACACACAGTTCAGATTTCC
 161 ACCTCTTTATAGACAAGAAGTGAATTTGCCTGGGGCAGAACACCCACCCAAAGAGTCCCCACTTAACAATACCCCCCCCC
 241 CACGGCAAGAATGCCCAAATCCGAATGACCCCAGTTTTCCTAATGAGTAAAATGATCCCAGATGTGCCCCAGAGCATGAC
 321 GCCTGCAGCTCCGGTTTCATGCAGGAAATTGGTTTTGGAGAGTTTTGGCAAGTTGGAAAGCCACTTACTGGCTTTTGACA
 401 TGACTTCTCTTGGAGAATAAGTGGACTCCAAGCTAACTCTTTGCAAATGTAAACACATGTCCATCTTGTAATAAATGCAA
 481 AATGCCCGTGCAGCAGAAGCATGCGACTTTCATATCCTTGCCTAGAATAGGCTGCATGGTGTATGTCAGTGAGGGCCACG
 561 AGGCGTCGGCTTTAGACACAGATCATAGCTCTACAGGAGTTTATGAATTTGAAGCTTATGGGATTTTGGCAGAGAAATTT
 641 TCAGCTGTGCTTGATACCCACCAAAAGAATGTATCTCGAAAGAATGAAGGAAGAAGAAAAAAGGATCCTTGATGTTTGTG
 721 ACAAGAAAATGAGAAAGTTAGTATCTGCAATACAGAGCTTGTTCCTGTTCAGTGACTGACCCTCTGTATTCTGTATAGAC
 801 ACCAGGCCGATACACAGTGGAGTTCCCAGGCCTTGTTTGCAGGAAGCCGACTGTAAAGACAGCCCCAGCTCAAGGCTATT
 881 AGGTTGAATATTTGCTTTCATGAGTAAATGTGGATCTTTGGGGAATGGCTTCAAAATAAGTCACGAACACAAATTCTTTG
 961 TAAATTATGTAAATTCCTGTTTATATAAATTGGCAACAACTTATACCGTCTGACAGTTCAAAATCTCTTTCAGCTGCGCT
1041 CTTCCCACCGAGCCGAGCTTACTGTGAGTGTGGAGATGTTATCCCACCATGTAAAGTCGCCTGCGCAGGGGAGGGCTGCC
1121 CATCTCCCCAACCCAGTCACAGAGAGATAGGAAACGGCATTTGAGTGGGTGTCCAGGGCCCCGTAGAGAGACATTTAAGA
1201 TGGTGTATGACAGAGCATTGGCCTTGACCAAATGTTAAATCCTCTGTGTGTATTTCATAAGTTATTACAGGTATAAAAGT
1281 GATGACCTATCATGAGGAAATGAAAGTGGCTGATTTGCTGGTAGGATTTTGTACAGTTTAGAGAAGCGATTATTTATTGT
1361 GAAACTGTTCTCCACTCCAACTCCTTTATGTGGATCTGTTCAAAGTAGTCACTGTATATACGTATAGAGAGGTAGATAGG
1441 TAGGTAGATTTTAAATTGCATTCTGAATACAAACTCATACTCCTTAGAGCTTGAATTACATTTTTAAAATGCATATGTGC
1521 TGTTTGGCACCGTGGCAAGATGGTATCAGAGAGAAACCCATCAATTGCTCAAATACTCAGAAAGTACTGTCAAAAGCCTA
1601 ATAAAAAACCTAAAGTTTGCTCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uccuCUUCCGUGGUACCCUAAAu 5'
              ||| || ::||||||||| 
Target 5' atttGAA-GC-TTATGGGATTTt 3'
 607 - 627 161.00 -14.60
2 
miRNA  3' ucCUCU-UCCGUGGUACCCUAAAu 5'
            |||| ||| |  | || |||| 
Target 5' gaGAGATAGGAA--ACGGCATTTg 3'
 1142 - 1163 129.00 -10.34
3 
miRNA  3' uccucuuccgugguacCCUAAAu 5'
                          |||||| 
Target 5' ggctgatttgctggtaGGATTTt 3'
 1308 - 1330 120.00 -5.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
897566 27 ClinVar
16647 46 ClinVar
897567 61 ClinVar
339126 64 ClinVar
339127 65 ClinVar
339128 137 ClinVar
339129 189 ClinVar
339130 231 ClinVar
339131 231 ClinVar
339132 231 ClinVar
1202313 232 ClinVar
339133 232 ClinVar
339134 236 ClinVar
339135 236 ClinVar
898723 236 ClinVar
339136 237 ClinVar
898724 237 ClinVar
339137 238 ClinVar
339138 239 ClinVar
339139 240 ClinVar
895749 240 ClinVar
895750 242 ClinVar
895751 258 ClinVar
339140 264 ClinVar
339141 270 ClinVar
339142 448 ClinVar
895752 569 ClinVar
339143 624 ClinVar
339144 664 ClinVar
339145 678 ClinVar
339146 679 ClinVar
339147 693 ClinVar
896031 699 ClinVar
339148 772 ClinVar
896032 801 ClinVar
896033 809 ClinVar
339149 849 ClinVar
897623 850 ClinVar
339150 924 ClinVar
339151 957 ClinVar
339152 997 ClinVar
339153 1008 ClinVar
897624 1009 ClinVar
339154 1050 ClinVar
339155 1055 ClinVar
898784 1056 ClinVar
339156 1105 ClinVar
339157 1204 ClinVar
898785 1216 ClinVar
339158 1240 ClinVar
898786 1269 ClinVar
339159 1348 ClinVar
339160 1364 ClinVar
339161 1386 ClinVar
339162 1491 ClinVar
895819 1610 ClinVar
COSM8878963 2 COSMIC
COSM1615771 3 COSMIC
COSM1153944 5 COSMIC
COSM8419253 7 COSMIC
COSM1483796 9 COSMIC
COSM6093700 13 COSMIC
COSM9487339 26 COSMIC
COSM2765290 35 COSMIC
COSM5576611 42 COSMIC
COSM8649127 45 COSMIC
COSM4680203 46 COSMIC
COSM3963726 62 COSMIC
COSM5350635 64 COSMIC
COSM7980116 64 COSMIC
COSM1204929 65 COSMIC
COSM5530345 76 COSMIC
COSM5858219 79 COSMIC
COSM9107710 85 COSMIC
COSM1681807 89 COSMIC
COSM4756029 92 COSMIC
COSN30463851 94 COSMIC
COSN30481979 96 COSMIC
COSN26974533 115 COSMIC
COSN26974532 122 COSMIC
COSN30183106 137 COSMIC
COSN31574547 139 COSMIC
COSN30504121 143 COSMIC
COSN31599081 180 COSMIC
COSN30448374 183 COSMIC
COSN30448953 194 COSMIC
COSN5766195 201 COSMIC
COSN30189172 210 COSMIC
COSN30189195 211 COSMIC
COSN30450903 214 COSMIC
COSN20121975 232 COSMIC
COSN1251304 242 COSMIC
COSN20116630 242 COSMIC
COSN6422072 242 COSMIC
COSN26434045 263 COSMIC
COSN5446700 290 COSMIC
COSN1878104 323 COSMIC
COSN27301743 489 COSMIC
COSN1878105 501 COSMIC
COSN28898127 708 COSMIC
COSN25433887 766 COSMIC
COSN1878106 909 COSMIC
COSN28201286 939 COSMIC
COSN31522968 949 COSMIC
COSN31547387 1002 COSMIC
COSN21114135 1173 COSMIC
COSN22006963 1541 COSMIC
COSN23873956 1620 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs761573030 2 dbSNP
rs781257967 6 dbSNP
rs1251006257 17 dbSNP
rs941911524 23 dbSNP
rs748005608 27 dbSNP
rs772906477 28 dbSNP
rs1482144958 30 dbSNP
rs532030990 31 dbSNP
rs137985872 39 dbSNP
rs201352056 40 dbSNP
rs1163140220 41 dbSNP
rs370508486 45 dbSNP
rs11570351 46 dbSNP
rs761106361 47 dbSNP
rs764620452 49 dbSNP
rs754204521 51 dbSNP
rs200741552 53 dbSNP
rs757559436 61 dbSNP
rs765500226 63 dbSNP
rs372958987 64 dbSNP
rs144250756 65 dbSNP
rs1381824847 67 dbSNP
rs549116987 73 dbSNP
rs756038575 75 dbSNP
rs767213063 77 dbSNP
rs777702187 79 dbSNP
rs749112686 83 dbSNP
rs1429701253 85 dbSNP
rs770841292 86 dbSNP
rs774182574 87 dbSNP
rs1180696320 89 dbSNP
rs1185806690 92 dbSNP
rs376137509 93 dbSNP
rs138451394 94 dbSNP
rs1004679269 100 dbSNP
rs774891807 103 dbSNP
rs760163643 107 dbSNP
rs370288393 111 dbSNP
rs1045052631 113 dbSNP
rs1275539899 116 dbSNP
rs777109038 119 dbSNP
rs374488792 121 dbSNP
rs368688196 122 dbSNP
rs750823872 127 dbSNP
rs750694380 129 dbSNP
rs567494206 136 dbSNP
rs200872063 137 dbSNP
rs751597991 140 dbSNP
rs1363304300 141 dbSNP
rs1305906995 145 dbSNP
rs1207508364 147 dbSNP
rs463415 151 dbSNP
rs1252768834 156 dbSNP
rs555946641 158 dbSNP
rs571072081 171 dbSNP
rs538768879 174 dbSNP
rs970107700 179 dbSNP
rs1463087616 181 dbSNP
rs1370889256 182 dbSNP
rs979253286 185 dbSNP
rs553876011 186 dbSNP
rs886056875 189 dbSNP
rs1167739044 205 dbSNP
rs1252840766 206 dbSNP
rs1197829598 218 dbSNP
rs1030078945 228 dbSNP
rs1053285924 230 dbSNP
rs886056876 231 dbSNP
rs886056877 231 dbSNP
rs886056878 231 dbSNP
rs11475273 232 dbSNP
rs1223307468 232 dbSNP
rs1392842069 232 dbSNP
rs1491361388 232 dbSNP
rs397866060 232 dbSNP
rs752653775 232 dbSNP
rs754876648 232 dbSNP
rs886056879 232 dbSNP
rs953126688 233 dbSNP
rs1431370866 234 dbSNP
rs1469810032 234 dbSNP
rs1431396628 235 dbSNP
rs372569173 235 dbSNP
rs71321536 236 dbSNP
rs1462675627 237 dbSNP
rs377130048 237 dbSNP
rs886056880 237 dbSNP
rs886056881 238 dbSNP
rs11570352 239 dbSNP
rs1334084942 240 dbSNP
rs576673862 240 dbSNP
rs544095029 241 dbSNP
rs1363468749 242 dbSNP
rs565501608 242 dbSNP
rs1446643692 243 dbSNP
rs918012816 244 dbSNP
rs3026576 245 dbSNP
rs1286882802 257 dbSNP
rs11570353 258 dbSNP
rs1350350680 261 dbSNP
rs925245673 263 dbSNP
rs3026575 264 dbSNP
rs11570354 270 dbSNP
rs1320160252 271 dbSNP
rs527379112 272 dbSNP
rs1398756757 287 dbSNP
rs1384031758 294 dbSNP
rs548702985 298 dbSNP
rs1163944123 305 dbSNP
rs1426862210 312 dbSNP
rs1056166329 321 dbSNP
rs896308632 322 dbSNP
rs1475761997 324 dbSNP
rs1012117157 325 dbSNP
rs892710743 333 dbSNP
rs746504168 334 dbSNP
rs997731228 340 dbSNP
rs1292044198 341 dbSNP
rs1452130018 345 dbSNP
rs1051847553 352 dbSNP
rs1225169716 356 dbSNP
rs1187897072 381 dbSNP
rs1361164522 391 dbSNP
rs1227273516 400 dbSNP
rs903773873 400 dbSNP
rs1246092521 401 dbSNP
rs888882445 405 dbSNP
rs567211087 411 dbSNP
rs533368307 413 dbSNP
rs1325780964 417 dbSNP
rs1303552760 434 dbSNP
rs79786751 448 dbSNP
rs1188964159 449 dbSNP
rs1163123808 450 dbSNP
rs1032996553 457 dbSNP
rs1407867760 458 dbSNP
rs1166227776 461 dbSNP
rs1475409009 469 dbSNP
rs956046535 488 dbSNP
rs963097929 489 dbSNP
rs1456012411 498 dbSNP
rs1489950048 505 dbSNP
rs1019071595 506 dbSNP
rs191496604 538 dbSNP
rs1456218438 540 dbSNP
rs546331828 543 dbSNP
rs1438013187 554 dbSNP
rs1274579865 558 dbSNP
rs143382055 560 dbSNP
rs1026264708 561 dbSNP
rs930923325 565 dbSNP
rs538479580 568 dbSNP
rs1292701180 569 dbSNP
rs549881140 570 dbSNP
rs992662058 574 dbSNP
rs1356482570 576 dbSNP
rs1326951441 593 dbSNP
rs1409380933 599 dbSNP
rs1437802987 603 dbSNP
rs1407510148 615 dbSNP
rs1179147783 623 dbSNP
rs11570355 624 dbSNP
rs1429071485 629 dbSNP
rs1340108844 635 dbSNP
rs1470340220 640 dbSNP
rs969475238 649 dbSNP
rs1056134961 654 dbSNP
rs1456897018 658 dbSNP
rs1263198976 661 dbSNP
rs1286057940 663 dbSNP
rs886056882 664 dbSNP
rs777130895 676 dbSNP
rs886056883 678 dbSNP
rs886056884 679 dbSNP
rs566044970 688 dbSNP
rs1208173920 690 dbSNP
rs1266237103 691 dbSNP
rs11570356 693 dbSNP
rs1209141635 694 dbSNP
rs1255161916 697 dbSNP
rs1421722806 699 dbSNP
rs1380992079 700 dbSNP
rs1277961999 710 dbSNP
rs1446159321 719 dbSNP
rs936727641 725 dbSNP
rs1044926207 726 dbSNP
rs1189240764 728 dbSNP
rs770384486 730 dbSNP
rs1368659564 732 dbSNP
rs1052859723 742 dbSNP
rs1000764014 744 dbSNP
rs1052388621 746 dbSNP
rs778461322 747 dbSNP
rs770340747 754 dbSNP
rs1010248036 766 dbSNP
rs886056885 772 dbSNP
rs933531165 783 dbSNP
rs1175174233 795 dbSNP
rs746433345 801 dbSNP
rs775994244 805 dbSNP
rs1184893461 807 dbSNP
rs531531144 809 dbSNP
rs1037450926 810 dbSNP
rs1318449490 811 dbSNP
rs1401891549 814 dbSNP
rs952238558 815 dbSNP
rs898902242 818 dbSNP
rs1383792463 827 dbSNP
rs1317319913 829 dbSNP
rs1450465554 840 dbSNP
rs763311172 849 dbSNP
rs57724975 850 dbSNP
rs1433477121 852 dbSNP
rs1336464434 854 dbSNP
rs6026809 856 dbSNP
rs1026360439 865 dbSNP
rs1158418773 867 dbSNP
rs1356333213 868 dbSNP
rs1385413565 872 dbSNP
rs895752974 883 dbSNP
rs1442194999 887 dbSNP
rs1014152765 891 dbSNP
rs1286474850 898 dbSNP
rs961656793 899 dbSNP
rs566560322 901 dbSNP
rs1240208146 902 dbSNP
rs969903180 905 dbSNP
rs1360453977 907 dbSNP
rs1294136554 917 dbSNP
rs1243901492 922 dbSNP
rs886056886 924 dbSNP
rs775734185 945 dbSNP
rs917636261 946 dbSNP
rs3026573 957 dbSNP
rs988164029 964 dbSNP
rs1405863881 986 dbSNP
rs1201946561 991 dbSNP
rs764393299 994 dbSNP
rs1256497485 995 dbSNP
rs886056887 997 dbSNP
rs987703726 999 dbSNP
rs1456041408 1005 dbSNP
rs751714665 1007 dbSNP
rs11570357 1008 dbSNP
rs1038241486 1009 dbSNP
rs766229089 1013 dbSNP
rs1192670100 1014 dbSNP
rs559330652 1015 dbSNP
rs1490438968 1019 dbSNP
rs1270751626 1029 dbSNP
rs1220589317 1034 dbSNP
rs1473875110 1038 dbSNP
rs929023512 1039 dbSNP
rs753749070 1040 dbSNP
rs1306276921 1041 dbSNP
rs1160519547 1045 dbSNP
rs3026572 1050 dbSNP
rs1347833448 1051 dbSNP
rs996258007 1054 dbSNP
rs138371508 1055 dbSNP
rs559849084 1056 dbSNP
rs1298263010 1061 dbSNP
rs1463012133 1064 dbSNP
rs1376307636 1066 dbSNP
rs572054658 1081 dbSNP
rs1480705910 1085 dbSNP
rs1306297912 1091 dbSNP
rs1431252074 1092 dbSNP
rs1352453958 1098 dbSNP
rs542670565 1099 dbSNP
rs13037048 1100 dbSNP
rs1015094347 1104 dbSNP
rs11570358 1105 dbSNP
rs752457788 1106 dbSNP
rs1204901894 1108 dbSNP
rs1257479211 1108 dbSNP
rs1280705893 1111 dbSNP
rs992209180 1112 dbSNP
rs1202539469 1115 dbSNP
rs1232917707 1119 dbSNP
rs958169170 1124 dbSNP
rs1253485304 1141 dbSNP
rs796328216 1145 dbSNP
rs917569991 1145 dbSNP
rs988657907 1146 dbSNP
rs1330089423 1156 dbSNP
rs1470295946 1157 dbSNP
rs980546441 1158 dbSNP
rs1170604351 1160 dbSNP
rs1021018894 1169 dbSNP
rs1364624572 1174 dbSNP
rs1190119329 1180 dbSNP
rs1184307090 1182 dbSNP
rs181368086 1183 dbSNP
rs549350852 1184 dbSNP
rs1178724685 1185 dbSNP
rs1184267785 1186 dbSNP
rs910811899 1189 dbSNP
rs1463060171 1201 dbSNP
rs886056888 1204 dbSNP
rs376536945 1216 dbSNP
rs920733019 1218 dbSNP
rs1351785390 1219 dbSNP
rs11570359 1237 dbSNP
rs3026571 1240 dbSNP
rs1047958809 1242 dbSNP
rs569486179 1245 dbSNP
rs901835869 1249 dbSNP
rs1271661439 1251 dbSNP
rs1452649627 1255 dbSNP
rs1372626708 1272 dbSNP
rs777354262 1273 dbSNP
rs547284575 1289 dbSNP
rs1462618868 1292 dbSNP
rs1292942204 1298 dbSNP
rs1365418791 1310 dbSNP
rs1385448259 1337 dbSNP
rs1160079138 1347 dbSNP
rs12322 1348 dbSNP
rs190002794 1349 dbSNP
rs1319488425 1350 dbSNP
rs1164297331 1354 dbSNP
rs886056889 1364 dbSNP
rs895566151 1368 dbSNP
rs1388394552 1373 dbSNP
rs746507182 1374 dbSNP
rs1236252068 1376 dbSNP
rs6015474 1385 dbSNP
rs536369470 1386 dbSNP
rs1044054186 1388 dbSNP
rs770418007 1389 dbSNP
rs1448080647 1390 dbSNP
rs554865283 1405 dbSNP
rs1364238700 1407 dbSNP
rs1225870950 1413 dbSNP
rs905782904 1414 dbSNP
rs1214830933 1415 dbSNP
rs1487108995 1418 dbSNP
rs1276418937 1422 dbSNP
rs1000499175 1423 dbSNP
rs1361039835 1432 dbSNP
rs1054364341 1433 dbSNP
rs780553745 1437 dbSNP
rs1015063143 1438 dbSNP
rs1326935470 1450 dbSNP
rs1320056449 1460 dbSNP
rs1432141997 1465 dbSNP
rs1397836540 1471 dbSNP
rs1263113879 1475 dbSNP
rs6026810 1484 dbSNP
rs886056890 1491 dbSNP
rs898019947 1500 dbSNP
rs1013831825 1501 dbSNP
rs1162726404 1508 dbSNP
rs1025689812 1512 dbSNP
rs1375218356 1518 dbSNP
rs1487812058 1520 dbSNP
rs1488142354 1532 dbSNP
rs548692162 1533 dbSNP
rs1222827270 1536 dbSNP
rs1452967674 1554 dbSNP
rs1287198138 1564 dbSNP
rs980855872 1571 dbSNP
rs1032067309 1574 dbSNP
rs183354781 1576 dbSNP
rs1279970464 1578 dbSNP
rs879641938 1585 dbSNP
rs957792738 1588 dbSNP
rs1339647900 1592 dbSNP
rs570404603 1596 dbSNP
rs746455039 1598 dbSNP
rs6026811 1599 dbSNP
rs913724402 1602 dbSNP
rs1348298631 1603 dbSNP
rs1010065773 1610 dbSNP
rs6026812 1611 dbSNP
rs1399292707 1620 dbSNP
rs1169227855 1624 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC-D2
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1133252. RNA binding protein: AGO2. Condition:Untreated ...

- Majoros WH; Lekprasert P; Mukherjee N; et al., 2013, Nature methods.

Article - Majoros WH; Lekprasert P; Mukherjee N; et al.
- Nature methods, 2013
High-throughput sequencing has opened numerous possibilities for the identification of regulatory RNA-binding events. Cross-linking and immunoprecipitation of Argonaute proteins can pinpoint a microRNA (miRNA) target site within tens of bases but leaves the identity of the miRNA unresolved. A flexible computational framework, microMUMMIE, integrates sequence with cross-linking features and reliably identifies the miRNA family involved in each binding event. It considerably outperforms sequence-only approaches and quantifies the prevalence of noncanonical binding modes.
LinkOut: [PMID: 23708386]
CLIP-seq Support 1 for dataset GSM1133252
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC-D2 / Untreated
Location of target site ENST00000311585.7 | 3UTR | UUGGCAGAGAAAUUUUCAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23708386 / GSE46611
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
HNSC 0.445 0.04 0.394 0.07 16 Click to see details
KICH -0.442 0.05 -0.375 0.08 15 Click to see details
LUSC 0.346 0.05 0.276 0.1 23 Click to see details
LUAD 0.548 0.06 0.633 0.03 9 Click to see details
CHOL -0.961 0.09 -1.000 0.5 3 Click to see details
BLCA 0.395 0.11 0.264 0.22 11 Click to see details
UCEC -0.416 0.13 -0.500 0.09 9 Click to see details
LIHC 0.23 0.16 0.357 0.06 20 Click to see details
THCA 0.111 0.23 0.166 0.13 48 Click to see details
KIRC -0.149 0.23 -0.166 0.2 27 Click to see details
KIRP -0.138 0.3 -0.265 0.15 17 Click to see details
STAD 0.132 0.3 0.112 0.33 18 Click to see details
PAAD -0.487 0.34 -0.500 0.33 3 Click to see details
BRCA 0.042 0.39 0.099 0.26 46 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
PRAD -0.037 0.47 -0.476 0.12 8 Click to see details
107 hsa-miR-605-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT001230 SEC24D SEC24 homolog D, COPII coat complex component 3 1
MIRT016155 TP53 tumor protein p53 2 1
MIRT016156 TCEAL1 transcription elongation factor A like 1 1 1
MIRT016157 MDM2 MDM2 proto-oncogene 2 1
MIRT040476 YBX1 Y-box binding protein 1 1 1
MIRT040477 TMEM64 transmembrane protein 64 1 1
MIRT040478 KDM5C lysine demethylase 5C 1 1
MIRT040479 TRAF4 TNF receptor associated factor 4 1 1
MIRT040480 DRG1 developmentally regulated GTP binding protein 1 1 1
MIRT040481 BCL9 B-cell CLL/lymphoma 9 1 1
MIRT055125 SCD stearoyl-CoA desaturase 2 2
MIRT057521 CEP55 centrosomal protein 55 2 2
MIRT081129 LDLR low density lipoprotein receptor 2 6
MIRT096817 ZSWIM6 zinc finger SWIM-type containing 6 2 4
MIRT100961 CENPQ centromere protein Q 2 4
MIRT263338 ANAPC16 anaphase promoting complex subunit 16 2 2
MIRT274710 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT311193 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT360127 DEK DEK proto-oncogene 2 2
MIRT438269 PSMD10 proteasome 26S subunit, non-ATPase 10 2 1
MIRT442464 SLC25A13 solute carrier family 25 member 13 2 2
MIRT446110 TSC22D2 TSC22 domain family member 2 2 2
MIRT463119 ZNF507 zinc finger protein 507 2 2
MIRT470566 POU2F1 POU class 2 homeobox 1 2 2
MIRT475059 IVNS1ABP influenza virus NS1A binding protein 2 6
MIRT482538 ACTB actin beta 2 4
MIRT494136 DCAF7 DDB1 and CUL4 associated factor 7 2 6
MIRT495209 EDN3 endothelin 3 2 2
MIRT495235 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT496762 MANBAL mannosidase beta like 2 2
MIRT498885 ZNF12 zinc finger protein 12 2 10
MIRT499280 NBPF11 NBPF member 11 2 2
MIRT507063 H3F3B H3 histone family member 3B 2 2
MIRT508352 HES7 hes family bHLH transcription factor 7 2 8
MIRT510740 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT519872 ZFP62 ZFP62 zinc finger protein 2 4
MIRT521272 RTN4 reticulon 4 2 4
MIRT522324 NFIB nuclear factor I B 2 6
MIRT525011 ACTN4 actinin alpha 4 2 6
MIRT526608 AASDH aminoadipate-semialdehyde dehydrogenase 2 4
MIRT529043 ARL9 ADP ribosylation factor like GTPase 9 2 2
MIRT529545 ZNF678 zinc finger protein 678 2 2
MIRT532500 HOXA13 homeobox A13 2 2
MIRT532599 SIX4 SIX homeobox 4 2 2
MIRT534044 STK4 serine/threonine kinase 4 2 2
MIRT534087 SPPL3 signal peptide peptidase like 3 2 2
MIRT534249 SLC16A1 solute carrier family 16 member 1 2 2
MIRT534286 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534555 RUNX1 runt related transcription factor 1 2 2
MIRT536765 HOXB2 homeobox B2 2 2
MIRT537227 GAN gigaxonin 2 2
MIRT551105 TTC8 tetratricopeptide repeat domain 8 2 2
MIRT552247 DUSP3 dual specificity phosphatase 3 2 2
MIRT554361 SFXN5 sideroflexin 5 2 2
MIRT557402 H3F3C H3 histone family member 3C 2 2
MIRT559116 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT560494 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT562296 GLO1 glyoxalase I 2 2
MIRT562597 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT563857 ALYREF Aly/REF export factor 2 4
MIRT565665 SIX1 SIX homeobox 1 2 2
MIRT568253 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT609593 GPM6B glycoprotein M6B 2 2
MIRT611552 GGT6 gamma-glutamyltransferase 6 2 2
MIRT613451 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT615516 PRRC2A proline rich coiled-coil 2A 2 2
MIRT617766 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT619134 MCOLN3 mucolipin 3 2 2
MIRT621365 CAP2 cyclase associated actin cytoskeleton regulatory protein 2 2 2
MIRT625804 MDC1 mediator of DNA damage checkpoint 1 2 2
MIRT626954 PRDM2 PR/SET domain 2 2 2
MIRT627716 RCAN1 regulator of calcineurin 1 2 2
MIRT628069 KCNJ13 potassium voltage-gated channel subfamily J member 13 2 2
MIRT630451 GTPBP8 GTP binding protein 8 (putative) 2 2
MIRT635533 ELMOD2 ELMO domain containing 2 2 2
MIRT636206 SULF2 sulfatase 2 2 2
MIRT638763 EPHA4 EPH receptor A4 2 2
MIRT640324 STAT1 signal transducer and activator of transcription 1 2 2
MIRT644548 SPOP speckle type BTB/POZ protein 2 2
MIRT645114 TMX2 thioredoxin related transmembrane protein 2 2 2
MIRT647778 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT650112 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT650136 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT650310 SLC35E2 solute carrier family 35 member E2 2 2
MIRT650930 ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2 2
MIRT651018 ZNF740 zinc finger protein 740 2 2
MIRT653541 SLC38A9 solute carrier family 38 member 9 2 2
MIRT655752 NR2C2 nuclear receptor subfamily 2 group C member 2 2 2
MIRT656908 KIAA1958 KIAA1958 2 2
MIRT657854 GJD3 gap junction protein delta 3 2 2
MIRT658215 FBXO21 F-box protein 21 2 2
MIRT659884 CAPN7 calpain 7 2 2
MIRT659922 CACNA1E calcium voltage-gated channel subunit alpha1 E 2 2
MIRT660055 C12orf5 TP53 induced glycolysis regulatory phosphatase 1 1
MIRT664616 LIMD1 LIM domains containing 1 2 2
MIRT665392 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT667887 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT669018 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT688419 DUSP2 dual specificity phosphatase 2 2 2
MIRT691888 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT709530 GEN1 GEN1, Holliday junction 5' flap endonuclease 2 2
MIRT711013 ABCD2 ATP binding cassette subfamily D member 2 2 2
MIRT714731 CENPH centromere protein H 2 2
MIRT719897 PTGIS prostaglandin I2 synthase 2 2
MIRT725028 CX3CL1 C-X3-C motif chemokine ligand 1 2 2
MIRT734348 P2RY12 purinergic receptor P2Y12 3 0
MIRT736719 TNFAIP3 TNF alpha induced protein 3 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Navitoclax 24978538 NSC759659 sensitive High Colorectal Cancer cell line (HCT-116, CHL1)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (BxPC‐3, PANC‐1)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1155)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved resistant Low Colon Cancer cell line (HT-29, LoVo)
hsa-miR-605-5p Everolimus + Panobinostat sensitive Low Clear Cell Renal Cell Carcinoma tissue
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-605-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-605-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-605-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-605-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-605-5p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVCAR3)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved resistant cell line (H460)
hsa-miR-605-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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