miRTarBase - #MIRT495380


—
pre-miRNA Information
pre-miRNA hsa-mir-4323   
Genomic Coordinates chr19: 42133445 - 42133513
Description Homo sapiens miR-4323 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4323
Sequence 42| CAGCCCCACAGCCUCAGA |59
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs549311114 1 dbSNP
rs896027609 6 dbSNP
rs1057502968 11 dbSNP
rs773276005 11 dbSNP
rs1454618841 12 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RELT   
Synonyms TNFRSF19L, TRLT
Description RELT, TNF receptor
Transcript NM_032871   
Other Transcripts NM_152222   
Expression
Putative miRNA Targets on RELT
3'UTR of RELT
(miRNA target sites are highlighted)		 
>RELT|NM_032871|3'UTR
   1 GGGGCGGTCTAGTCTAAGGACACTGCGGCCCTGCCCTGGGAGGTTCCGAAGGCTTCCTGGAGGAGGTGGAGCTGCAGCTG
  81 GGACTGTGAGGACCGAGAAGCAATGGCCCAGCAGACGAGACAGCAAAGACCAAGGCCTGGAGGTGGGAGCGTCTGCCCCA
 161 GTGAGGAGGCAGGTGGCCGGCGGGCACTGTGTACAGGAGCAGGCTGAGCCCCGCCCCTGGCCCTGCTGCCATGTTGCTCC
 241 CCTGAAGGATGCCCCGACCCCCGTGCCTGCCCTGGCTGGATCCTAGGAGCCCACGGGATTCTCTGTATCATCAGAGGCTG
 321 GGCTTGGCAGAGGGGAGGGGCCTGTGCCCGTCACCCCTGGCCCCATTCCTTGGTAATTAGCCACACCCTTGCCTCTGTAC
 401 AGGGCCCTAGAGCAGATGTGCGTCCCCCTCCTCTTCCAGCAGGTCTATAAAGGGAAGGGGTAGCAGAAAGTCCTGGGCTA
 481 GGAGAGTGAGTCCCTGGGTTCTAATCTTGGGCACATCTGTGGCCATCGCTGGGTCCATTTTTCTGACTGTGAAGTAAGGA
 561 GAGACGTCTCAGTACCCAGGGCCTCTTCAGCTCTTTGTAGGTTCTGGGCTGGGTTGTGGGGGACTGGGGAGCTGGGCTCT
 641 ACCATCCCTCCCATTAGTAGCTTTATCCAGCCCCGTTTTTGCTGCTTCCAGGGCCTCTGCCTTCAAGGCCCCCATGGGGC
 721 TGTCCATCCATGGCTCTGCCTACGGAAGGGGCTTAATGCATGTGCCTGCCCCTCCCCCAGCTGTTTTTAATGAAACTGAA
 801 AAAATAGACTTGATCCCGGCAGGACTGTGATACAGAGCCCTAGCCTGCCCAGCCAGCCCCAAGATCTCAGGAGCTTTAGG
 881 GAGAAGACTTGGTGGGGCTGGAGCACACCTTGGGCCTCAGTGGTTTCTGTGTCCCTGTGGTGCCAGTGCTTCTGGGCAGT
 961 GCAGGCGGCTGCCAGGCCCAGCCCTGACTTCCACTCTGGCTCAGCAACCTGGTTATTTATGTGGGGCCGTGCAGGCATGG
1041 GCCCACTGCCTGTCCATCCTGTTTCTCTTATTTATTGAAACTCACCATTGCCCTATCCTTGTGTCTCCACCCCCTTCCAT
1121 GTGTTGAATAATAAAAGGTGGGAAAGTGCTGTCACGAGGAGCTCCTTTTCTCTGTGCCCTTCCCAGCTTATCCGCCTGTT
1201 CCACTTGTACCTGTCCAGCCCTGCCCTGTGTTGGGCACCGTGACAGGCTGCCCTCCCCTCACAGTTCCTGCACCTCAGCA
1281 GCCAGGGAAGCAGGGCCCAGAGGAGACCCATCAACTCATCTGGTTCTCACCAAAGCCCCTAGCTAGAGGCAGGGCTGTCC
1361 CACAGAAATAGTGTGAGCCACATATGTGACTTTAAATTTTCTGACAGTCACATTTCAAAAAGTAAAAAGAAGCAGGTGAA
1441 CTTAATTTTTTTTTAACCCAGTCTATCCAAAATATTTTCATTTCAATATAAAATCAGTATAAAAAGTGTGAATGAGCTGT
1521 TTTTGCTTTTGCTTTGAAATCTGGAGTGTATCTTACACATCTTGATTGGAACTCAAATATTTCAAGGGCTCCATAGCCAC
1601 GTGGCCAGCAGCTACCACACTGGTCAGCGCAGCACCTGAGGAAATGCACTGTGTGGAGCCCGGGAGGTAATTGGGGGTGA
1681 GGAAGATGTGCGGGCCAGGGAATGTGTTCCACAGAGAGGGACAGCATGTGCAAAGGCTGAGCACCAACACATAGTGGTCA
1761 CCTGGGCCTTATGCCCAGGGAGCCTCCAAAGCATTCAGCTCCTGCTTGGCCAGTGTGGAGAGGAAAGGAGCCACAGGAGC
1841 GGGTGCTACACCCGGCAAGACAGAGCGTCTCCATCTAAAATTCCTAGGGCAAGCTTCCAACCCGGCCCAAGGGCCGCATG
1921 TGGCCCAGGATATGGCTTTGAATGGGGCCTAACACAAATTCATAAACTTTCTTAAAACATTGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agacUCCGA--CACCCCGAc 5'
              || ||  |||||||| 
Target 5' gagaAGACTTGGTGGGGCTg 3'
 881 - 900 152.00 -18.70
2 
miRNA  3' agacUCC---GACACCCCGAc 5'
              |||   |  ||||||| 
Target 5' ttcaAGGCCCCCATGGGGCTg 3'
 702 - 722 142.00 -18.90
3 
miRNA  3' agacuccgACACCCCGac 5'
                  ||||||||  
Target 5' gttatttaTGTGGGGCcg 3'
 1012 - 1029 130.00 -14.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9330711 1 COSMIC
COSN31612660 6 COSMIC
COSN30131463 7 COSMIC
COSN24381431 28 COSMIC
COSN16130192 83 COSMIC
COSN31600574 97 COSMIC
COSN28198158 108 COSMIC
COSN28644943 155 COSMIC
COSN23345745 344 COSMIC
COSN31579837 488 COSMIC
COSN26580494 602 COSMIC
COSN31595894 625 COSMIC
COSN24796059 725 COSMIC
COSN31585119 745 COSMIC
COSN1542547 882 COSMIC
COSN23133947 1136 COSMIC
COSN8690216 1570 COSMIC
COSN5308943 1594 COSMIC
COSN28547752 1632 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs199685145 2 dbSNP
rs993563325 6 dbSNP
rs759999427 7 dbSNP
rs765704635 8 dbSNP
rs1156650972 11 dbSNP
rs755016369 13 dbSNP
rs753110058 14 dbSNP
rs1200901081 15 dbSNP
rs758678729 16 dbSNP
rs777548974 17 dbSNP
rs1283256381 19 dbSNP
rs751106718 24 dbSNP
rs1354625638 25 dbSNP
rs572192450 27 dbSNP
rs376164534 28 dbSNP
rs745337997 31 dbSNP
rs372176962 34 dbSNP
rs922266949 37 dbSNP
rs746029911 39 dbSNP
rs373679123 41 dbSNP
rs368373127 48 dbSNP
rs768264998 49 dbSNP
rs1259876867 58 dbSNP
rs970352143 59 dbSNP
rs981371372 60 dbSNP
rs1362001054 65 dbSNP
rs1036042790 70 dbSNP
rs752466889 73 dbSNP
rs1171367187 78 dbSNP
rs987836002 79 dbSNP
rs913671597 86 dbSNP
rs1173864149 90 dbSNP
rs1474362955 95 dbSNP
rs549478807 96 dbSNP
rs982778522 100 dbSNP
rs908597351 105 dbSNP
rs926486351 107 dbSNP
rs1255225766 110 dbSNP
rs1160549406 113 dbSNP
rs1347487999 117 dbSNP
rs937909683 118 dbSNP
rs1221042633 122 dbSNP
rs941451288 127 dbSNP
rs974187050 133 dbSNP
rs1337961380 140 dbSNP
rs1433255315 144 dbSNP
rs921445683 151 dbSNP
rs932840830 152 dbSNP
rs7101831 155 dbSNP
rs777277127 159 dbSNP
rs1413755149 161 dbSNP
rs929305812 165 dbSNP
rs71479526 167 dbSNP
rs771222376 172 dbSNP
rs1407731139 173 dbSNP
rs535242594 179 dbSNP
rs1047818753 180 dbSNP
rs934311822 182 dbSNP
rs779956683 183 dbSNP
rs1297075061 185 dbSNP
rs892870205 189 dbSNP
rs1187002860 190 dbSNP
rs1006767455 191 dbSNP
rs1017764164 196 dbSNP
rs1477454237 204 dbSNP
rs1393050935 209 dbSNP
rs112422566 211 dbSNP
rs997702550 213 dbSNP
rs1346794675 214 dbSNP
rs539400224 214 dbSNP
rs1320672268 216 dbSNP
rs905680098 217 dbSNP
rs1233082834 218 dbSNP
rs138827253 224 dbSNP
rs1035602614 229 dbSNP
rs1348837080 234 dbSNP
rs987770721 240 dbSNP
rs1021090807 245 dbSNP
rs967818027 254 dbSNP
rs557504918 256 dbSNP
rs539420981 257 dbSNP
rs937857381 263 dbSNP
rs1231238434 264 dbSNP
rs1414716924 269 dbSNP
rs1015565579 271 dbSNP
rs1178217484 272 dbSNP
rs1468849612 274 dbSNP
rs555923104 279 dbSNP
rs1232342795 280 dbSNP
rs1252939137 289 dbSNP
rs576000798 294 dbSNP
rs929251758 295 dbSNP
rs921372302 296 dbSNP
rs1175954533 300 dbSNP
rs1047729823 307 dbSNP
rs770396244 318 dbSNP
rs1309299784 319 dbSNP
rs987382628 323 dbSNP
rs1169377513 332 dbSNP
rs1039549813 334 dbSNP
rs1458406068 335 dbSNP
rs1352252157 340 dbSNP
rs900664206 340 dbSNP
rs1156728252 341 dbSNP
rs1399136979 343 dbSNP
rs997651579 350 dbSNP
rs141976672 351 dbSNP
rs1441629662 358 dbSNP
rs892056210 370 dbSNP
rs1370182942 377 dbSNP
rs934926700 380 dbSNP
rs1010481116 387 dbSNP
rs1052745102 388 dbSNP
rs914229171 392 dbSNP
rs1489124111 393 dbSNP
rs1267569440 395 dbSNP
rs947062447 398 dbSNP
rs778442005 399 dbSNP
rs1020618264 403 dbSNP
rs541530090 406 dbSNP
rs866900850 419 dbSNP
rs905641697 422 dbSNP
rs11544309 423 dbSNP
rs1241596879 427 dbSNP
rs1368141648 427 dbSNP
rs1033860772 431 dbSNP
rs772596590 437 dbSNP
rs1057366343 442 dbSNP
rs1286851774 447 dbSNP
rs367971378 448 dbSNP
rs1360063157 453 dbSNP
rs1309274575 455 dbSNP
rs1421818339 460 dbSNP
rs1393327283 462 dbSNP
rs1175504884 479 dbSNP
rs917805719 482 dbSNP
rs1273062700 483 dbSNP
rs34583063 492 dbSNP
rs566175904 506 dbSNP
rs368264967 510 dbSNP
rs1485747247 514 dbSNP
rs775854175 528 dbSNP
rs1196108252 529 dbSNP
rs1233370332 548 dbSNP
rs1254005042 548 dbSNP
rs929199435 552 dbSNP
rs1185505858 566 dbSNP
rs371673027 567 dbSNP
rs983812785 578 dbSNP
rs1340885947 582 dbSNP
rs1299862410 596 dbSNP
rs145619290 603 dbSNP
rs1170803359 609 dbSNP
rs1302284317 625 dbSNP
rs1466626196 627 dbSNP
rs1379807637 638 dbSNP
rs1393165159 640 dbSNP
rs1477813001 645 dbSNP
rs1028374335 646 dbSNP
rs533085200 651 dbSNP
rs1196348431 653 dbSNP
rs942052790 653 dbSNP
rs1350188156 654 dbSNP
rs769021267 657 dbSNP
rs1255065618 664 dbSNP
rs1200463306 671 dbSNP
rs777316536 671 dbSNP
rs954273689 673 dbSNP
rs760956731 675 dbSNP
rs912738185 676 dbSNP
rs956222834 688 dbSNP
rs989046978 690 dbSNP
rs1051873355 692 dbSNP
rs1312280449 693 dbSNP
rs892005653 694 dbSNP
rs914868334 696 dbSNP
rs1296572810 705 dbSNP
rs868208395 709 dbSNP
rs1369055198 710 dbSNP
rs1465534437 718 dbSNP
rs1450492730 724 dbSNP
rs11544308 730 dbSNP
rs1401701953 735 dbSNP
rs947026278 744 dbSNP
rs980181848 745 dbSNP
rs1216091142 750 dbSNP
rs927022092 752 dbSNP
rs1187802063 753 dbSNP
rs938446792 760 dbSNP
rs1446722718 765 dbSNP
rs201960927 766 dbSNP
rs186378345 769 dbSNP
rs1176760767 775 dbSNP
rs1476179289 777 dbSNP
rs1033397399 785 dbSNP
rs940550962 793 dbSNP
rs776716703 797 dbSNP
rs1265867892 799 dbSNP
rs1245764111 806 dbSNP
rs1473943825 810 dbSNP
rs762137685 811 dbSNP
rs959117316 817 dbSNP
rs1013374250 818 dbSNP
rs1414477333 819 dbSNP
rs1399856461 834 dbSNP
rs1024808858 836 dbSNP
rs1460392142 838 dbSNP
rs1390440482 839 dbSNP
rs1164243320 841 dbSNP
rs899096400 842 dbSNP
rs1459089179 848 dbSNP
rs1361732882 852 dbSNP
rs1177403827 861 dbSNP
rs1439773929 863 dbSNP
rs995428655 880 dbSNP
rs1028761514 887 dbSNP
rs1191653982 890 dbSNP
rs1400822202 897 dbSNP
rs1451014713 898 dbSNP
rs1290288138 899 dbSNP
rs889848865 909 dbSNP
rs1358677721 913 dbSNP
rs1008718651 928 dbSNP
rs1019720234 929 dbSNP
rs1239781395 935 dbSNP
rs1354489976 937 dbSNP
rs956191883 940 dbSNP
rs989014578 953 dbSNP
rs1439307176 955 dbSNP
rs1021848677 963 dbSNP
rs968959577 967 dbSNP
rs1350622756 968 dbSNP
rs1222599498 977 dbSNP
rs1003662336 979 dbSNP
rs1286771365 982 dbSNP
rs979766981 985 dbSNP
rs1216804715 1010 dbSNP
rs926964131 1013 dbSNP
rs1378712924 1016 dbSNP
rs938388492 1029 dbSNP
rs765388397 1030 dbSNP
rs1247238574 1034 dbSNP
rs907669191 1035 dbSNP
rs1189055777 1039 dbSNP
rs940494998 1042 dbSNP
rs1262279475 1044 dbSNP
rs540373910 1055 dbSNP
rs1037501572 1056 dbSNP
rs11544310 1057 dbSNP
rs1488764532 1059 dbSNP
rs1156800488 1062 dbSNP
rs1050743 1066 dbSNP
rs1288210211 1070 dbSNP
rs931906467 1071 dbSNP
rs975157607 1079 dbSNP
rs190646425 1092 dbSNP
rs889768439 1099 dbSNP
rs1008269774 1108 dbSNP
rs1020111897 1112 dbSNP
rs1420086229 1113 dbSNP
rs11235735 1114 dbSNP
rs1010367878 1121 dbSNP
rs1051821551 1156 dbSNP
rs535229481 1157 dbSNP
rs946222051 1160 dbSNP
rs182811759 1164 dbSNP
rs904776546 1165 dbSNP
rs1174234449 1176 dbSNP
rs1474415070 1178 dbSNP
rs1334877895 1180 dbSNP
rs980746626 1187 dbSNP
rs1335312835 1188 dbSNP
rs1488713827 1191 dbSNP
rs1034630157 1194 dbSNP
rs544543684 1195 dbSNP
rs866184439 1199 dbSNP
rs1279498713 1203 dbSNP
rs1202683715 1207 dbSNP
rs1316641619 1208 dbSNP
rs894850972 1211 dbSNP
rs1013320868 1214 dbSNP
rs1341926166 1214 dbSNP
rs959971645 1215 dbSNP
rs1446909739 1218 dbSNP
rs992540412 1219 dbSNP
rs1335666743 1222 dbSNP
rs1408100636 1224 dbSNP
rs1234049593 1225 dbSNP
rs907590854 1226 dbSNP
rs950550343 1235 dbSNP
rs1478680949 1238 dbSNP
rs879048648 1240 dbSNP
rs961788798 1254 dbSNP
rs1180327199 1256 dbSNP
rs1279115369 1257 dbSNP
rs1005140547 1259 dbSNP
rs563218289 1268 dbSNP
rs1345258098 1272 dbSNP
rs1016142113 1273 dbSNP
rs920416831 1274 dbSNP
rs1257995048 1278 dbSNP
rs1256224776 1280 dbSNP
rs1320431751 1323 dbSNP
rs1436787010 1330 dbSNP
rs755855994 1331 dbSNP
rs1239953039 1338 dbSNP
rs533483425 1343 dbSNP
rs911849445 1358 dbSNP
rs1192802764 1370 dbSNP
rs1379480344 1372 dbSNP
rs944005484 1374 dbSNP
rs1443950570 1380 dbSNP
rs112771703 1382 dbSNP
rs921919465 1383 dbSNP
rs1173446820 1385 dbSNP
rs954738286 1386 dbSNP
rs118144735 1389 dbSNP
rs1163864256 1396 dbSNP
rs186447562 1405 dbSNP
rs946199289 1406 dbSNP
rs756922076 1408 dbSNP
rs1437911215 1410 dbSNP
rs557994815 1427 dbSNP
rs1459509660 1431 dbSNP
rs778351968 1431 dbSNP
rs979348165 1435 dbSNP
rs1221322067 1442 dbSNP
rs1291580527 1446 dbSNP
rs1378331990 1446 dbSNP
rs1237589835 1450 dbSNP
rs368652714 1465 dbSNP
rs1301678051 1466 dbSNP
rs1249274912 1467 dbSNP
rs116291144 1469 dbSNP
rs113352458 1472 dbSNP
rs1448867099 1475 dbSNP
rs190860045 1487 dbSNP
rs1001748792 1488 dbSNP
rs1350618942 1507 dbSNP
rs1436950547 1507 dbSNP
rs183899381 1511 dbSNP
rs1418153151 1513 dbSNP
rs745383347 1517 dbSNP
rs568413582 1519 dbSNP
rs960322372 1521 dbSNP
rs760286150 1523 dbSNP
rs534085748 1525 dbSNP
rs1190905293 1528 dbSNP
rs949044889 1536 dbSNP
rs1248874725 1543 dbSNP
rs1458132655 1545 dbSNP
rs1213983735 1549 dbSNP
rs1487783212 1549 dbSNP
rs1241717181 1551 dbSNP
rs758840677 1557 dbSNP
rs187599691 1558 dbSNP
rs886189777 1564 dbSNP
rs747622151 1574 dbSNP
rs961717071 1577 dbSNP
rs973109773 1578 dbSNP
rs899022170 1589 dbSNP
rs768874202 1599 dbSNP
rs953328379 1607 dbSNP
rs540805382 1608 dbSNP
rs1455412477 1620 dbSNP
rs1357563830 1621 dbSNP
rs115332509 1622 dbSNP
rs985991995 1627 dbSNP
rs911756010 1628 dbSNP
rs944656592 1629 dbSNP
rs1474445371 1630 dbSNP
rs1191994527 1636 dbSNP
rs1041036391 1639 dbSNP
rs1401187686 1640 dbSNP
rs1218084711 1645 dbSNP
rs1388834333 1662 dbSNP
rs557565285 1663 dbSNP
rs369225895 1668 dbSNP
rs987437589 1672 dbSNP
rs1313910386 1678 dbSNP
rs1276014696 1681 dbSNP
rs1416581210 1686 dbSNP
rs1217799355 1689 dbSNP
rs946052714 1692 dbSNP
rs1043159118 1693 dbSNP
rs1384190383 1700 dbSNP
rs1020293048 1705 dbSNP
rs1302378959 1717 dbSNP
rs1301474185 1718 dbSNP
rs967857572 1721 dbSNP
rs1168911243 1723 dbSNP
rs904640032 1724 dbSNP
rs577431439 1735 dbSNP
rs880317 1741 dbSNP
rs1421729220 1742 dbSNP
rs1254820387 1751 dbSNP
rs1181958755 1755 dbSNP
rs937551817 1756 dbSNP
rs1279512794 1760 dbSNP
rs1198004489 1769 dbSNP
rs1318316850 1774 dbSNP
rs991711447 1775 dbSNP
rs1229850072 1776 dbSNP
rs896028027 1795 dbSNP
rs1338960949 1799 dbSNP
rs567882546 1807 dbSNP
rs1464315578 1821 dbSNP
rs770173126 1830 dbSNP
rs1385532020 1832 dbSNP
rs1232538478 1836 dbSNP
rs1015154802 1839 dbSNP
rs1401455589 1841 dbSNP
rs571426621 1841 dbSNP
rs1456016624 1842 dbSNP
rs1164785566 1844 dbSNP
rs1445917060 1852 dbSNP
rs961686814 1854 dbSNP
rs773359426 1855 dbSNP
rs1260829064 1862 dbSNP
rs1445473317 1866 dbSNP
rs994497584 1867 dbSNP
rs192611028 1868 dbSNP
rs1354442937 1879 dbSNP
rs1265092215 1882 dbSNP
rs1474923477 1887 dbSNP
rs1163331068 1889 dbSNP
rs1370725422 1897 dbSNP
rs1307237802 1898 dbSNP
rs898964658 1901 dbSNP
rs1288619569 1902 dbSNP
rs995987268 1904 dbSNP
rs138762577 1905 dbSNP
rs1426212168 1910 dbSNP
rs1299662067 1916 dbSNP
rs750245872 1917 dbSNP
rs1440186609 1927 dbSNP
rs1018791081 1935 dbSNP
rs966299615 1937 dbSNP
rs1196404046 1942 dbSNP
rs559866298 1948 dbSNP
rs1340537782 1950 dbSNP
rs1223475406 1965 dbSNP
rs1232178261 1972 dbSNP
rs1283911901 1975 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC-D2
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1133252. RNA binding protein: AGO2. Condition:Untreated ...

- Majoros WH; Lekprasert P; Mukherjee N; et al., 2013, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agacuccgaCACCCCGAc 5'
                   |||||||| 
Target 5' ------uugGUGGGGCUg 3'
 		1 - 12
Article - Majoros WH; Lekprasert P; Mukherjee N; et al.
- Nature methods, 2013
High-throughput sequencing has opened numerous possibilities for the identification of regulatory RNA-binding events. Cross-linking and immunoprecipitation of Argonaute proteins can pinpoint a microRNA (miRNA) target site within tens of bases but leaves the identity of the miRNA unresolved. A flexible computational framework, microMUMMIE, integrates sequence with cross-linking features and reliably identifies the miRNA family involved in each binding event. It considerably outperforms sequence-only approaches and quantifies the prevalence of noncanonical binding modes.
LinkOut: [PMID: 23708386]
CLIP-seq Support 1 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_152222 | 3UTR | AGAAGACUUGGUGGGGCUGGAGCACACCUUGGGCCUCAGUGGUUUCUGUGUCCCUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1133252
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC-D2 / Untreated
Location of target site ENST00000064780.2 | 3UTR | UUGGUGGGGCUGGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23708386 / GSE46611
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
64 hsa-miR-4323 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT052834 NOL11 nucleolar protein 11 1 1
MIRT082489 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT117166 PER1 period circadian clock 1 2 2
MIRT157951 TMEM184B transmembrane protein 184B 2 2
MIRT286013 TVP23B trans-golgi network vesicle protein 23 homolog B 2 2
MIRT310457 REST RE1 silencing transcription factor 2 2
MIRT338984 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT404223 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT451439 TJP3 tight junction protein 3 2 2
MIRT463541 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT466981 STARD7 StAR related lipid transfer domain containing 7 2 4
MIRT479627 CDC25A cell division cycle 25A 2 2
MIRT487983 SEC14L3 SEC14 like lipid binding 3 2 4
MIRT488661 ELAVL3 ELAV like RNA binding protein 3 2 2
MIRT489925 RTKN rhotekin 2 2
MIRT490209 PKNOX2 PBX/knotted 1 homeobox 2 2 2
MIRT494896 ZNF662 zinc finger protein 662 2 2
MIRT495380 RELT RELT, TNF receptor 2 2
MIRT495549 ANKRD65 ankyrin repeat domain 65 2 2
MIRT499104 AGRN agrin 2 2
MIRT500036 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501135 SLC2A1 solute carrier family 2 member 1 2 2
MIRT505573 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT508164 ABCC5 ATP binding cassette subfamily C member 5 2 8
MIRT512383 PHB2 prohibitin 2 2 2
MIRT512719 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT520904 STMN1 stathmin 1 2 2
MIRT526361 TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 2 2
MIRT526847 GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 2 2
MIRT526945 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 4
MIRT527028 PABPN1L poly(A) binding protein nuclear 1 like, cytoplasmic 2 2
MIRT527988 TSLP thymic stromal lymphopoietin 2 2
MIRT532202 MPDU1 mannose-P-dolichol utilization defect 1 2 2
MIRT533691 TMEM86A transmembrane protein 86A 2 2
MIRT535020 PRMT7 protein arginine methyltransferase 7 2 4
MIRT535054 PQLC1 PQ loop repeat containing 1 2 2
MIRT538987 BCL2L2 BCL2 like 2 2 2
MIRT552232 SART3 squamous cell carcinoma antigen recognized by T-cells 3 2 2
MIRT553259 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT555157 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT565202 TSC22D4 TSC22 domain family member 4 2 2
MIRT566199 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT566526 PARP16 poly(ADP-ribose) polymerase family member 16 2 2
MIRT568464 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT572231 ATG2A autophagy related 2A 2 2
MIRT573096 NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 2 2
MIRT573326 RFC5 replication factor C subunit 5 2 2
MIRT632802 KIAA2022 neurite extension and migration factor 2 2
MIRT646433 ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2 3
MIRT647826 MTG1 mitochondrial ribosome associated GTPase 1 2 4
MIRT652191 TRIM44 tripartite motif containing 44 2 2
MIRT653800 SIRPA signal regulatory protein alpha 2 2
MIRT666949 PKHD1 PKHD1, fibrocystin/polyductin 2 2
MIRT684833 SCAI suppressor of cancer cell invasion 2 2
MIRT687294 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT700188 RIMKLB ribosomal modification protein rimK like family member B 2 2
MIRT701784 MSL2 MSL complex subunit 2 2 2
MIRT705958 ACY1 aminoacylase 1 2 2
MIRT705998 ABHD14A-ACY1 ABHD14A-ACY1 readthrough 2 2
MIRT717107 PXDC1 PX domain containing 1 2 2
MIRT717586 VTA1 vesicle trafficking 1 2 2
MIRT722148 SLC2A8 solute carrier family 2 member 8 2 2
MIRT723479 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT725221 PEA15 phosphoprotein enriched in astrocytes 15 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4323 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4323 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-4323 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-4323 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-4323 Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-mir-4323 Vincristine 5978 approved sensitive cell line (W1)
hsa-mir-4323 Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)
hsa-miR-4323 Tripterygium wilfordii Hook F resistant tissue
hsa-miR-4323 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4323 Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4323 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4323 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

Error report submission