miRTarBase - #MIRT495762


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pre-miRNA Information
pre-miRNA hsa-mir-938   
Genomic Coordinates chr10: 29602264 - 29602346
Synonyms MIRN938, hsa-mir-938, MIR938
Description Homo sapiens miR-938 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-938
Sequence 15| UGCCCUUAAAGGUGAACCCAGU |36
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN28704008 2 COSMIC
COSN31533921 5 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs12416605 2 dbSNP
rs1348880424 3 dbSNP
rs1205636191 4 dbSNP
rs757919276 12 dbSNP
rs754296125 14 dbSNP
rs573596343 17 dbSNP
rs756660742 18 dbSNP
rs753092730 21 dbSNP
Putative Targets

Gene Information
Gene Symbol ZNF607   
Synonyms -
Description zinc finger protein 607
Transcript NM_001172677   
Other Transcripts NM_032689   
Expression
Putative miRNA Targets on ZNF607
3'UTR of ZNF607
(miRNA target sites are highlighted)		 
>ZNF607|NM_001172677|3'UTR
   1 TAGAGAAATTGTGGCATATACAGGTAGTAAAGAAAGCACATTGTGTCAATGGATTTATCCCACTGAACAATTTGAATGAA
  81 GACAATGTGGAATGGCTTTGAGATACAGTTCAGTTTTTATTAGGCATCAATTTGTATTGGTGTGAACTTTTCAAAATGTA
 161 AATCATATATGCAGTTTCTTTGGTATGACCTGTGTTAACTCAGATTCAGAGAATTTATAATGTATTTTTTTAATAACATA
 241 AGAAAACTTTTCTGATATTCCTCTAGTTTTGGATTGCCAAAATATTCACAGTAGAGGAAAACTGAGAAAACGTAGGAAAC
 321 CATTCTTTATACTTGCATGTAAACATCTTCCAGCAACAATCATTTATTGTTAAACCTGGAAAAAGCCATTACACAGGAAA
 401 CCTCTGTTGATATAAGCGATGATGGGAAAGGCTATTTAGCCACTCTGCATATTTAATGCTCATGATCAACATCTGCTTCC
 481 TATAGCTGGGATGATATGGGGGAAGATATTTATCCCTTCTGGGGATCATATATAAATGATGATAGTAGTACCTACAGTAT
 561 AGTGCTGTTAGAATTACATGAGTTAGATGTGGAGGTCAGAGTGGAAGCAGGTGTGAGAGGGTCCCGCAGAAGAAAACATG
 641 GCTGCCAAAGTGTTTGAGTCCATCGGCAAGTTTGGCCTGGCCTTAGCTGTTGCAGGAGGCATGGTGAACTCTGCCTTATG
 721 TAATGTGGATGCTGGGCACAGAGCTGCCATCTTTGACCAATTCCGTGGAGTACAGAACATTGTGGTAGGGGAAGGGACTC
 801 ACTTTCTCATCCCATGTGTACAAAAACCAATTATCTTTGACTGCTGTTCTCAACCACGTAGTGCGCCAGTCATCACTGGT
 881 AGCAAAGATTTACAGAATGTCAACATCACACTGTGCATCCTCTTCCGGCCCATCACTAGCCAGCTTCCTCGCATCTTCAC
 961 CAGCATTGGAGAGGACTACGATGAGTGTGTGCTGCCGTTCATTACCACGGAGATCCTCAAGTCACTGGTGGCTCGCTTTG
1041 ATGCTGGAGAACTAATCACCCAGAGGGAGCTGGTCTCCAGCCAGGTGAGCAACAACCTTATGGAGTGAGCAGCCACCTTT
1121 GGGCTCATTCTGGACGACGTGTCTTTGACACATCTGACCTTCTTGAAGGAGTTAACAGACAGGTGGCCCCCCAGGAAGCA
1201 GAGAGCGCCAGATTTGTGGTGGAAAAGGCGGCCATCATCTCTGCTGAGGGTGACTCCAAGGCAGCTGAGCTGATCGCCAA
1281 CTCACTGGCCACTGCAGGGGACGGCCAGAGCGAGCTGTGCAAGCTGGAAGCTGCAGAAGACATTGCATACCAGCTCTCAT
1361 GCTCTCGGAACATCACCTGCCTGCCGGCAGGGCAGTCCGTGCTCCTCCAGCTGCCCTAGTGAGGCCCCAGCCTACCTGCA
1441 CCTCCGTGAGGCAACTGGGCCACAGCCCCGATGATTCGTAACACCACCTTTCGCCCTCACCCCAGAAATCACTGAAATTT
1521 CATGATTGGCTTAAAGTGAAGGAAGTAAAGGTAAAATCACTTCAGATCTCTAAAAAACAAAGAATTACATGAGTTAGTAC
1601 ATGAAAAAATTATGGGAAACTACATGAAATATACTGTTACGTTCAATAAACATTAGCTTCTGTATATAATAATATCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugacccaAGUGGA-A--AUUCCCGu 5'
                 |||:|| |  |:||||: 
Target 5' gcggccaTCATCTCTGCTGAGGGTg 3'
 1228 - 1252 121.00 -13.10
2 
miRNA  3' ugACC-CAAG---UGGAA----AUUCCCgu 5'
            ||| || |   || ||    ||:|||  
Target 5' cgTGGAGTACAGAACATTGTGGTAGGGGaa 3'
 764 - 793 114.00 -11.20
3 
miRNA  3' ugACCCAAGUGGAAAUUCCCgu 5'
            |||| | |  | |::|||  
Target 5' gcTGGGATGA--TATGGGGGaa 3'
 485 - 504 104.00 -15.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30112057 5 COSMIC
COSN22849071 29 COSMIC
COSN30523260 58 COSMIC
COSN31512332 90 COSMIC
COSN30526626 92 COSMIC
COSN512303 145 COSMIC
COSN30170075 177 COSMIC
COSN31558239 211 COSMIC
COSN31567514 538 COSMIC
COSN31524268 549 COSMIC
COSN31550445 562 COSMIC
COSN26505461 625 COSMIC
COSN6668527 640 COSMIC
COSN30470636 641 COSMIC
COSN26572410 643 COSMIC
COSN31502881 661 COSMIC
COSN26669552 664 COSMIC
COSN27006337 702 COSMIC
COSN28805008 708 COSMIC
COSN17183050 719 COSMIC
COSN26578275 747 COSMIC
COSN31574989 765 COSMIC
COSN26603595 789 COSMIC
COSN30470400 795 COSMIC
COSN30117671 877 COSMIC
COSN30101361 887 COSMIC
COSN30476274 890 COSMIC
COSN30535910 893 COSMIC
COSN8605698 899 COSMIC
COSN24306693 911 COSMIC
COSN30100457 912 COSMIC
COSN2529482 930 COSMIC
COSN18742945 931 COSMIC
COSN31512985 943 COSMIC
COSN8260168 951 COSMIC
COSN30138565 963 COSMIC
COSN31543574 968 COSMIC
COSN31533418 979 COSMIC
COSN30114181 1035 COSMIC
COSN30150324 1047 COSMIC
COSN26859349 1079 COSMIC
COSN31607154 1135 COSMIC
COSN31570073 1138 COSMIC
COSN30531840 1200 COSMIC
COSN31546296 1249 COSMIC
COSN13801933 1275 COSMIC
COSN26269239 1289 COSMIC
COSN30530306 1302 COSMIC
COSN31554678 1304 COSMIC
COSN1215139 1321 COSMIC
COSN30116152 1335 COSMIC
COSN32058101 1358 COSMIC
COSN30137960 1384 COSMIC
COSN24403025 1389 COSMIC
COSN26722210 1510 COSMIC
COSN27161274 1592 COSMIC
COSN20740439 1620 COSMIC
COSN23091907 1635 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs751800717 1 dbSNP
rs764464563 2 dbSNP
rs1293182880 3 dbSNP
rs758495663 11 dbSNP
rs533119644 13 dbSNP
rs765711545 16 dbSNP
rs192270194 22 dbSNP
rs776928995 24 dbSNP
rs886498862 39 dbSNP
rs368009766 43 dbSNP
rs1466576617 47 dbSNP
rs374093712 49 dbSNP
rs1300777026 64 dbSNP
rs1307010414 80 dbSNP
rs1378937329 81 dbSNP
rs1240785885 91 dbSNP
rs777261227 92 dbSNP
rs1353970540 94 dbSNP
rs1010536297 119 dbSNP
rs893473139 128 dbSNP
rs539350399 130 dbSNP
rs1001937731 131 dbSNP
rs1040018889 134 dbSNP
rs762671933 142 dbSNP
rs1236426425 143 dbSNP
rs906052622 150 dbSNP
rs1369253397 155 dbSNP
rs1171110488 168 dbSNP
rs925792752 170 dbSNP
rs1179787406 175 dbSNP
rs1368292708 183 dbSNP
rs1471991231 184 dbSNP
rs1164660128 190 dbSNP
rs761246910 190 dbSNP
rs1464654412 192 dbSNP
rs189582689 196 dbSNP
rs1430788963 201 dbSNP
rs565308927 202 dbSNP
rs1401830774 212 dbSNP
rs1046293310 222 dbSNP
rs1447492123 232 dbSNP
rs1333398550 236 dbSNP
rs547092199 245 dbSNP
rs1171003210 246 dbSNP
rs978542878 250 dbSNP
rs945814943 254 dbSNP
rs1218231984 258 dbSNP
rs1014520410 260 dbSNP
rs529507024 261 dbSNP
rs1256290361 263 dbSNP
rs886652783 280 dbSNP
rs1047965997 281 dbSNP
rs912961324 282 dbSNP
rs930680970 287 dbSNP
rs2287229 289 dbSNP
rs1189971020 293 dbSNP
rs1238408499 296 dbSNP
rs540787733 312 dbSNP
rs1481993344 313 dbSNP
rs1425204935 316 dbSNP
rs1253871592 321 dbSNP
rs980355957 328 dbSNP
rs943425606 336 dbSNP
rs1399890376 337 dbSNP
rs1016457634 342 dbSNP
rs747757009 352 dbSNP
rs1005025346 357 dbSNP
rs886553769 367 dbSNP
rs1346842584 375 dbSNP
rs1277962571 376 dbSNP
rs1030814138 380 dbSNP
rs911743291 383 dbSNP
rs1228172170 392 dbSNP
rs1255926789 400 dbSNP
rs1220551614 401 dbSNP
rs1202693463 402 dbSNP
rs1281557239 403 dbSNP
rs1345301640 406 dbSNP
rs1191108851 408 dbSNP
rs1278377210 409 dbSNP
rs375716022 413 dbSNP
rs966653684 417 dbSNP
rs150986505 418 dbSNP
rs1173057134 421 dbSNP
rs1359698652 422 dbSNP
rs989388618 426 dbSNP
rs1038971045 434 dbSNP
rs957719908 445 dbSNP
rs942638225 446 dbSNP
rs545850096 449 dbSNP
rs1382987705 461 dbSNP
rs1300749048 465 dbSNP
rs904418623 469 dbSNP
rs2909091 470 dbSNP
rs769211534 473 dbSNP
rs1304742253 482 dbSNP
rs945850073 497 dbSNP
rs1332635026 502 dbSNP
rs1288590100 506 dbSNP
rs1486030527 507 dbSNP
rs200511504 514 dbSNP
rs1264716775 517 dbSNP
rs1434349703 518 dbSNP
rs913018386 522 dbSNP
rs1379539634 524 dbSNP
rs1437608336 525 dbSNP
rs1387971458 536 dbSNP
rs1160296179 545 dbSNP
rs970853501 551 dbSNP
rs1024482998 556 dbSNP
rs1014877526 560 dbSNP
rs1388691971 571 dbSNP
rs1426141014 578 dbSNP
rs1158272644 583 dbSNP
rs112990056 589 dbSNP
rs73621573 594 dbSNP
rs568089249 604 dbSNP
rs185469562 608 dbSNP
rs142866942 610 dbSNP
rs1235468101 622 dbSNP
rs1243641858 625 dbSNP
rs34625192 626 dbSNP
rs779543999 626 dbSNP
rs1263276428 629 dbSNP
rs566642261 632 dbSNP
rs983643593 637 dbSNP
rs950947003 640 dbSNP
rs911926280 662 dbSNP
rs1030464686 664 dbSNP
rs1226239328 665 dbSNP
rs1422974722 676 dbSNP
rs1164382809 678 dbSNP
rs998010555 680 dbSNP
rs557812533 681 dbSNP
rs539474445 693 dbSNP
rs192590242 694 dbSNP
rs1399604443 701 dbSNP
rs913722966 704 dbSNP
rs55743020 708 dbSNP
rs1333900137 720 dbSNP
rs957914610 722 dbSNP
rs745841797 723 dbSNP
rs1310154876 724 dbSNP
rs980398448 724 dbSNP
rs1042948990 726 dbSNP
rs1010102654 727 dbSNP
rs891634167 728 dbSNP
rs1315504623 734 dbSNP
rs970418395 736 dbSNP
rs563880065 749 dbSNP
rs756232097 760 dbSNP
rs746868489 764 dbSNP
rs1179839394 765 dbSNP
rs1258012225 767 dbSNP
rs950975321 768 dbSNP
rs1390866246 772 dbSNP
rs927001867 773 dbSNP
rs1044114291 785 dbSNP
rs941659453 789 dbSNP
rs909503983 792 dbSNP
rs1464096801 794 dbSNP
rs983712004 796 dbSNP
rs1355567001 797 dbSNP
rs1026418081 801 dbSNP
rs529598985 802 dbSNP
rs187253160 806 dbSNP
rs899391339 807 dbSNP
rs1183590752 814 dbSNP
rs547236523 816 dbSNP
rs1415068434 817 dbSNP
rs2909090 818 dbSNP
rs1337811139 827 dbSNP
rs1219861041 857 dbSNP
rs923451072 858 dbSNP
rs59096662 860 dbSNP
rs1207901158 862 dbSNP
rs1206389903 864 dbSNP
rs139651004 865 dbSNP
rs1017623492 869 dbSNP
rs1188961686 874 dbSNP
rs1000859701 888 dbSNP
rs968011440 889 dbSNP
rs1052310317 910 dbSNP
rs530464967 912 dbSNP
rs1174548716 921 dbSNP
rs891688958 922 dbSNP
rs757118868 926 dbSNP
rs182911172 927 dbSNP
rs533685511 928 dbSNP
rs1401443757 931 dbSNP
rs936578550 932 dbSNP
rs1230570563 934 dbSNP
rs1366266948 938 dbSNP
rs1217430301 943 dbSNP
rs1380301391 946 dbSNP
rs957507863 948 dbSNP
rs1270004605 949 dbSNP
rs926486079 950 dbSNP
rs541415717 951 dbSNP
rs1367628752 954 dbSNP
rs887443937 964 dbSNP
rs1047367358 976 dbSNP
rs1487469627 979 dbSNP
rs949103331 980 dbSNP
rs765616972 981 dbSNP
rs976678257 984 dbSNP
rs917574789 990 dbSNP
rs1166787694 993 dbSNP
rs559226926 995 dbSNP
rs1405911246 996 dbSNP
rs982960205 997 dbSNP
rs1378825824 998 dbSNP
rs1402139406 1000 dbSNP
rs951106960 1001 dbSNP
rs1348829433 1008 dbSNP
rs1026449341 1009 dbSNP
rs146296003 1012 dbSNP
rs559189516 1017 dbSNP
rs755100379 1020 dbSNP
rs753898372 1021 dbSNP
rs968068281 1023 dbSNP
rs540858812 1035 dbSNP
rs766491724 1039 dbSNP
rs1017844829 1040 dbSNP
rs1225703933 1045 dbSNP
rs1007796754 1046 dbSNP
rs1192683840 1047 dbSNP
rs1451112211 1058 dbSNP
rs192290556 1060 dbSNP
rs1219385912 1062 dbSNP
rs1254946616 1063 dbSNP
rs988131459 1066 dbSNP
rs1487201742 1067 dbSNP
rs890475357 1070 dbSNP
rs1030308988 1073 dbSNP
rs143629370 1079 dbSNP
rs1010077391 1084 dbSNP
rs1224366689 1085 dbSNP
rs1412550464 1101 dbSNP
rs892517834 1103 dbSNP
rs187946023 1127 dbSNP
rs539910432 1135 dbSNP
rs140031287 1136 dbSNP
rs557326990 1138 dbSNP
rs1329162435 1139 dbSNP
rs112718703 1143 dbSNP
rs1442580759 1158 dbSNP
rs1280370817 1163 dbSNP
rs541095495 1165 dbSNP
rs1226814091 1174 dbSNP
rs1047877864 1178 dbSNP
rs1335499938 1180 dbSNP
rs1198607400 1183 dbSNP
rs1386459228 1183 dbSNP
rs1256648532 1184 dbSNP
rs928966441 1189 dbSNP
rs1045413336 1191 dbSNP
rs1183062379 1193 dbSNP
rs949310979 1206 dbSNP
rs568785022 1207 dbSNP
rs1295381829 1208 dbSNP
rs547293624 1219 dbSNP
rs982436618 1225 dbSNP
rs535281856 1229 dbSNP
rs571049016 1230 dbSNP
rs1353862091 1234 dbSNP
rs1166713597 1237 dbSNP
rs973784677 1245 dbSNP
rs552764640 1274 dbSNP
rs1398469698 1275 dbSNP
rs1410450964 1276 dbSNP
rs1390603114 1278 dbSNP
rs1172585048 1279 dbSNP
rs1431119821 1281 dbSNP
rs1268771367 1285 dbSNP
rs1295312812 1286 dbSNP
rs756286375 1288 dbSNP
rs530634726 1293 dbSNP
rs183407383 1299 dbSNP
rs190696083 1302 dbSNP
rs529644441 1303 dbSNP
rs373991229 1311 dbSNP
rs559247214 1312 dbSNP
rs1203700093 1316 dbSNP
rs1441000846 1316 dbSNP
rs1484221410 1317 dbSNP
rs986803923 1317 dbSNP
rs540921872 1322 dbSNP
rs576665118 1323 dbSNP
rs954954908 1324 dbSNP
rs1257696789 1326 dbSNP
rs767741481 1333 dbSNP
rs988572521 1339 dbSNP
rs1232743307 1341 dbSNP
rs762213763 1347 dbSNP
rs1310676001 1349 dbSNP
rs1171883500 1356 dbSNP
rs7245981 1358 dbSNP
rs1219880912 1360 dbSNP
rs543204662 1361 dbSNP
rs1306082105 1363 dbSNP
rs981364497 1366 dbSNP
rs575713604 1367 dbSNP
rs969939407 1377 dbSNP
rs1328253941 1383 dbSNP
rs1032457595 1385 dbSNP
rs1228820313 1386 dbSNP
rs1274737052 1386 dbSNP
rs76141649 1389 dbSNP
rs1236875335 1390 dbSNP
rs1281474289 1392 dbSNP
rs543519615 1398 dbSNP
rs144374307 1399 dbSNP
rs1379004346 1401 dbSNP
rs1026060621 1405 dbSNP
rs1447041772 1406 dbSNP
rs1198088536 1409 dbSNP
rs993601889 1413 dbSNP
rs901515387 1423 dbSNP
rs1013930456 1437 dbSNP
rs1007785976 1439 dbSNP
rs149640717 1445 dbSNP
rs1180596510 1446 dbSNP
rs1047422299 1449 dbSNP
rs1323493562 1457 dbSNP
rs1382781055 1457 dbSNP
rs1369498817 1458 dbSNP
rs186184816 1464 dbSNP
rs889339961 1466 dbSNP
rs1473868486 1469 dbSNP
rs929679622 1470 dbSNP
rs946869649 1477 dbSNP
rs1043713439 1479 dbSNP
rs1208788780 1484 dbSNP
rs571112920 1492 dbSNP
rs1469798788 1496 dbSNP
rs552761502 1500 dbSNP
rs1194162617 1518 dbSNP
rs537217131 1522 dbSNP
rs1328527180 1530 dbSNP
rs939399249 1532 dbSNP
rs1365697041 1542 dbSNP
rs748955219 1545 dbSNP
rs928005100 1547 dbSNP
rs750447050 1550 dbSNP
rs1392332252 1558 dbSNP
rs1443814609 1561 dbSNP
rs980738882 1563 dbSNP
rs1376637790 1564 dbSNP
rs1389974356 1565 dbSNP
rs969990362 1577 dbSNP
rs4006732 1582 dbSNP
rs1243574637 1585 dbSNP
rs1270779955 1585 dbSNP
rs774815848 1588 dbSNP
rs951904809 1589 dbSNP
rs183270806 1591 dbSNP
rs1479542525 1608 dbSNP
rs1178787809 1609 dbSNP
rs1250964583 1610 dbSNP
rs1351040800 1612 dbSNP
rs1312007490 1616 dbSNP
rs993261493 1622 dbSNP
rs910720957 1632 dbSNP
rs1404151133 1634 dbSNP
rs1166307063 1636 dbSNP
rs547952451 1640 dbSNP
rs769380505 1641 dbSNP
rs1007169081 1643 dbSNP
rs1397632175 1644 dbSNP
rs1385740375 1652 dbSNP
rs1160757211 1656 dbSNP
rs1473817886 1657 dbSNP
rs889391757 1662 dbSNP
rs1233300840 1663 dbSNP
rs1277003787 1672 dbSNP
rs1413336102 1675 dbSNP
rs1206496707 1676 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BACD1 , LCL-BACD3
Disease MIMAT0004981
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020024. RNA binding protein: AGO2. Condition:EBV B95-8-infected "PAR-CLIP data was present in GSM1020025. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugacccaaGUGGAAAUUCCCgu 5'
                  :| ||||:: ||  
Target 5' -----gccUAACUUUGGUGG-- 3'
 		1 - 15
Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020024
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD1 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000355202.4 | 3UTR | GCCUAACUUUGGUGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1020025
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD3 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000355202.4 | 3UTR | GCCUAACUUUGGUGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE19350 CNS germ cell tumors -0.689 6.6e-3 -0.058 4.3e-1 12 Click to see details
GSE28260 Renal cortex and medulla 0.523 3.3e-2 0.297 1.6e-1 13 Click to see details
GSE38226 Liver fibrosis 0.401 3.6e-2 0.296 9.6e-2 21 Click to see details
GSE28544 Breast cancer -0.341 5.1e-2 -0.328 5.9e-2 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.232 1.3e-1 0.150 2.4e-1 25 Click to see details
GSE42095 Differentiated embryonic stem cells -0.233 1.4e-1 -0.318 7.0e-2 23 Click to see details
GSE21687 Ependynoma primary tumors -0.075 2.8e-1 -0.030 4.1e-1 64 Click to see details
GSE26953 Aortic valvular endothelial cells 0.1 3.2e-1 -0.119 2.9e-1 24 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.099 3.4e-1 0.496 1.3e-2 20 Click to see details
GSE32688 Pancreatic cancer 0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
GSE32688 Pancreatic cancer 0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
0.034 4.3e-1 0.203 1.3e-1 32 Click to see details
54 hsa-miR-938 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT073757 NUBP1 nucleotide binding protein 1 2 2
MIRT092006 SNRK SNF related kinase 2 12
MIRT218174 MRPL18 mitochondrial ribosomal protein L18 2 2
MIRT485452 IVNS1ABP influenza virus NS1A binding protein 2 2
MIRT489857 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT495407 SPPL3 signal peptide peptidase like 3 2 4
MIRT495762 ZNF607 zinc finger protein 607 2 2
MIRT497391 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT499227 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT507059 H3F3B H3 histone family member 3B 2 2
MIRT513671 SOCS5 suppressor of cytokine signaling 5 2 8
MIRT526922 IRGQ immunity related GTPase Q 2 4
MIRT527488 OCIAD1 OCIA domain containing 1 2 2
MIRT527566 ADCY7 adenylate cyclase 7 2 2
MIRT528081 NOL9 nucleolar protein 9 2 2
MIRT528535 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 4
MIRT533896 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT536523 KCTD10 potassium channel tetramerization domain containing 10 2 2
MIRT541382 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT550254 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT555975 NPTN neuroplastin 2 2
MIRT557394 H3F3C H3 histone family member 3C 2 2
MIRT568594 ADM adrenomedullin 2 2
MIRT571876 NCL nucleolin 2 2
MIRT572443 TRIM10 tripartite motif containing 10 2 2
MIRT610589 PRDM1 PR/SET domain 1 2 2
MIRT614044 THBS2 thrombospondin 2 2 2
MIRT618412 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT623398 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT623948 FBXO47 F-box protein 47 2 2
MIRT625349 MGLL monoglyceride lipase 2 2
MIRT635447 FAM180B family with sequence similarity 180 member B 2 2
MIRT638249 SLC16A9 solute carrier family 16 member 9 2 2
MIRT642662 RGS6 regulator of G protein signaling 6 2 2
MIRT646431 ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2 2
MIRT647172 ARGFX arginine-fifty homeobox 2 2
MIRT654891 POU2F1 POU class 2 homeobox 1 2 2
MIRT659337 CSE1L chromosome segregation 1 like 2 2
MIRT667407 MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2 2
MIRT698892 SPTBN2 spectrin beta, non-erythrocytic 2 2 2
MIRT703841 ETV3 ETS variant 3 2 2
MIRT708322 NT5C 5', 3'-nucleotidase, cytosolic 2 2
MIRT708934 CRY2 cryptochrome circadian clock 2 2 2
MIRT709745 UBD ubiquitin D 2 2
MIRT710265 FAM107A family with sequence similarity 107 member A 2 2
MIRT712576 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 2 2
MIRT712645 TXNL4A thioredoxin like 4A 2 2
MIRT714833 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT720673 SLC39A13 solute carrier family 39 member 13 2 2
MIRT723041 MAPT microtubule associated protein tau 2 2
MIRT723669 CTC1 CST telomere replication complex component 1 2 2
MIRT723772 ROBO4 roundabout guidance receptor 4 2 2
MIRT723812 OR1L8 olfactory receptor family 1 subfamily L member 8 2 2
MIRT736795 RBM5 RNA binding motif protein 5 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-938 Emodin NULL 3220 Microarray K562 cells 23744534 2013 down-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-938 Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1155)
hsa-miR-938 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-938 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-938 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-938 Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-938 Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-938 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-938 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-938 Paclitaxel 36314 NSC125973 approved sensitive cell line (PC3PR70)
hsa-miR-938 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-938 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-938 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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