miRTarBase - #MIRT495953


—
pre-miRNA Information
pre-miRNA hsa-mir-6756   
Genomic Coordinates chr11: 119312950 - 119313012
Description Homo sapiens miR-6756 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6756-3p
Sequence 44| UCCCCUUCCUCCCUGCCCAG |63
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1411959960 15 dbSNP
rs150069507 19 dbSNP
rs369323848 19 dbSNP
Putative Targets

Gene Information
Gene Symbol SLC12A7   
Synonyms KCC4
Description solute carrier family 12 member 7
Transcript NM_006598   
Expression
Putative miRNA Targets on SLC12A7
3'UTR of SLC12A7
(miRNA target sites are highlighted)		 
>SLC12A7|NM_006598|3'UTR
   1 TGCCCAACAGCATCACGGCACTCTGGGACAGGCACGGAGGACGGCGTGGGCAGCCTGGGCCTGGGCTTGGCCCAGGGAAA
  81 CAGACGGCAGACACACCTGTCCCCCAGTGATGCCGCCCAAGCTGCCCATGGGGCTTCCTACGGAAGTTTCTAGGCCCGTC
 161 ACCTAGGGCTCTCCTGTTCAGCCTTAACAGGCTCAGCAAATCAGGGCGTGGCTGGACGATTTCCTTGCATCTGAGGGCAG
 241 ACGCTGCTACCGGAGTGACCTGGACGTGGCCAGATCTTCTCGCAGGTCACAAGAAGCCAGTGAGCCCTTGCCTTGGTTTC
 321 TGGAAGTTCTTTTCCTTGGCTGGATTTACCCAGTGGTTAGGTTGCATTTCTACCCCATCCAGAACATTCTTGGAAGAGCA
 401 CCCGGAGCTGAAGCTGTCCCTGATGATGAAGGTGAAACGTCAGCCCTGGCCATGGCTCCGCTCAGGGCCCCGGTCACCTC
 481 CGAGTCACTCTGTTCCTTGACTGTCTTTGTGTTTCTGTACCTCAAGGCACTGAAGCTGGAGGACTCTGTCCATGCCCGTG
 561 TCACCCTCGTGTGGGAGCCTCTGGGCTCGGCAGGTCCACATTTCATGAGCTGAGGCGTGGGCCAGGGCCATCTGGAAAGG
 641 GAACTCGGCTTTTCCAGAACGTGGTGGATCATCTGTCGGGTGTGTGGTGAACACGTTCAGTTCATCAGGGCCTACGCTCC
 721 GGGAAGGGGCCCCCAGCTGTGGCTCTGCCATGCCGGGCTGTGTTTGCAGCTGTCCGAGTCTCCATCCACCTTTAGAAAAC
 801 CAGCCACTTCTTTTCATAAGCACTGACAGGGCCCAGCCCACAGCCACAGGTGCGATCAGTGCCTCACGCAGGCAAATGCA
 881 CTGAAACCCAGGGGCACACGCGCGCAGAGTGAACAGTGAGTTCCCCCGACAGCCCACGACAGCCAGGACTGCCCTCCCCA
 961 CCCCACCCCACCCCAGGAGCACGGCACACAGTTCAGCCTCTGAGCTGGCTCACACGTGCCATCCCCACCCCGGTGCTCCA
1041 GGGAAGGAGGACACGGACCCGACGTGGGAGGTCCTCAGGCAGCAGTGGCGCCTGGTGTCAGGTCTGTCTGGCTGAGTCCC
1121 GGGCGTCCCCTGCCATGGCCTGTGCCTTGCATGGAGGCGGCGGTGGCACTGAAGAGATAGCTTTCAAGGGCCCAACACTT
1201 TGCACTTCGGCTGGCTGTGAGTTTCTGCTTTGTAGGTTGTGGTCACATTTGCAGGCTGCGGGCAGTGGCACCGACTTGGG
1281 CCTCCCTTTCTATGTGGCATATTTATTTATTTAAACACCCCAGGGAGTTACGTGGTAACAAGGTTGTCCATAAAGAGGTT
1361 GCTTCTATATACTAGAGGCCCCAGATGGCCAGGCCTTGGGCTACGTCTGGCTTGCATGGTCTCCCAAGGGAATCAGCCCC
1441 ATCAACAAAGTTCAAATCGGGGCAGAGGCTGCACTTGTGCCCCCAGATGTTTCTGAGGAGCCAGACTAGGGCTGGCATTG
1521 CTGTAGAGTGACGGCTGCTGCCCAGAGCGTGTCCCAGACATCACAGCGGGGCTCAGCAGTTCCCACAGCCTCTGCCTGCC
1601 TTGGCTAAGCATGAGTTAAGCAGCAAAACGCTCCTCCATGTCTGGATGGGGCCGGCAGGTCCTGTGTCCCCTGCACCTGG
1681 AGGAGAGCAGGCTAGAGGCACAGCGGCCACATGGTGCTGGCTCTGAACGTTGGTTGGTGGCTGGAAAACAGCCCTGCTTC
1761 TGAGGGCCGCTCAGTTCTGCACACGAAACCACCTCCTGAGGGCTCAGCTCTGCCCCCGCCCTGGGCTGCAGCCTCTGCAC
1841 GCAAGCACCAGGCATCCTTTGTGTTGTCAACTCCGTGTAACCAGTAACTACAGCCATTTACAATTGACTCCGTTTCCTTT
1921 TGTAGGTTTCCCTGTCTGTCTGTGTTAGTAGAAAAATAAAATCCTATGAAATCTGAGTACGTTGAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaCCCG--UCC---CUCCUUCCCCu 5'
            ||||  | |    :|||||||| 
Target 5' caGGGCCTACGCTCCGGGAAGGGGc 3'
 706 - 730 148.00 -21.40
2 
miRNA  3' gaCCCGUCCC--U---CCUUCCCCu 5'
            || |||||  |   |||| ||| 
Target 5' tgGGCCAGGGCCATCTGGAAAGGGa 3'
 618 - 642 128.00 -23.20
3 
miRNA  3' gacccGUCCCUCCUUCCCCu 5'
               |||   |||||| | 
Target 5' tgctcCAG---GGAAGGAGg 3'
 1034 - 1050 116.00 -18.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN1304418 5 COSMIC
COSN30180939 14 COSMIC
COSN26994846 17 COSMIC
COSN30514828 18 COSMIC
COSN31505923 21 COSMIC
COSN31495706 23 COSMIC
COSN30101768 36 COSMIC
COSN31557373 42 COSMIC
COSN14132768 64 COSMIC
COSN26994852 98 COSMIC
COSN30492077 101 COSMIC
COSN20063672 115 COSMIC
COSN30452923 118 COSMIC
COSN18730268 128 COSMIC
COSN30515836 141 COSMIC
COSN28162395 142 COSMIC
COSN31543640 199 COSMIC
COSN28866557 207 COSMIC
COSN20661350 343 COSMIC
COSN6854260 500 COSMIC
COSN16502633 680 COSMIC
COSN26627715 799 COSMIC
COSN19517375 982 COSMIC
COSN1304400 1463 COSMIC
COSN6854168 1874 COSMIC
rs55861694 718 GWAS
rs56368594 1484 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1377072505 1 dbSNP
rs1243626338 2 dbSNP
rs1292882922 3 dbSNP
rs1010323118 4 dbSNP
rs370521503 7 dbSNP
rs1408269388 8 dbSNP
rs1453330953 9 dbSNP
rs748323947 15 dbSNP
rs375919144 16 dbSNP
rs758057508 17 dbSNP
rs750226125 18 dbSNP
rs1281839169 25 dbSNP
rs893173513 25 dbSNP
rs371589856 26 dbSNP
rs1307347007 30 dbSNP
rs764997044 32 dbSNP
rs757194885 33 dbSNP
rs373181971 34 dbSNP
rs760276501 35 dbSNP
rs763684141 36 dbSNP
rs767276232 41 dbSNP
rs759170780 42 dbSNP
rs368985127 43 dbSNP
rs771243015 45 dbSNP
rs773734659 46 dbSNP
rs1418516882 49 dbSNP
rs769803598 50 dbSNP
rs1165367418 51 dbSNP
rs748227509 57 dbSNP
rs1367669493 58 dbSNP
rs1406941985 58 dbSNP
rs781314229 63 dbSNP
rs1430548825 64 dbSNP
rs571203952 65 dbSNP
rs1297350247 66 dbSNP
rs200099495 66 dbSNP
rs559194290 67 dbSNP
rs777812942 67 dbSNP
rs778735600 69 dbSNP
rs1294663813 72 dbSNP
rs757033726 73 dbSNP
rs753779196 74 dbSNP
rs1410040033 76 dbSNP
rs1463386097 78 dbSNP
rs1271151224 84 dbSNP
rs114414556 85 dbSNP
rs370297309 86 dbSNP
rs547940217 88 dbSNP
rs529821126 91 dbSNP
rs759199235 96 dbSNP
rs1304948726 98 dbSNP
rs773909438 100 dbSNP
rs1389871036 101 dbSNP
rs1168316128 103 dbSNP
rs769401201 105 dbSNP
rs756276970 106 dbSNP
rs1193202664 108 dbSNP
rs1218491026 109 dbSNP
rs1045989384 113 dbSNP
rs766720998 114 dbSNP
rs3810854 115 dbSNP
rs773638768 118 dbSNP
rs1274273681 120 dbSNP
rs1197967040 124 dbSNP
rs748173313 128 dbSNP
rs770277712 128 dbSNP
rs1337826822 129 dbSNP
rs1047509337 130 dbSNP
rs776667034 133 dbSNP
rs768657423 138 dbSNP
rs182274157 141 dbSNP
rs777285619 142 dbSNP
rs770693755 146 dbSNP
rs749090414 150 dbSNP
rs1456008691 153 dbSNP
rs1304585895 154 dbSNP
rs756099332 157 dbSNP
rs191620269 158 dbSNP
rs1008426077 162 dbSNP
rs1215694173 164 dbSNP
rs1312386948 165 dbSNP
rs6890452 166 dbSNP
rs891322659 169 dbSNP
rs1292853081 171 dbSNP
rs1487991332 173 dbSNP
rs1169616092 176 dbSNP
rs199864690 176 dbSNP
rs1470433781 179 dbSNP
rs752724225 181 dbSNP
rs1010354215 184 dbSNP
rs1346374121 193 dbSNP
rs1477721588 194 dbSNP
rs780717352 198 dbSNP
rs1412716606 200 dbSNP
rs754473033 203 dbSNP
rs1346474719 205 dbSNP
rs76394500 207 dbSNP
rs1010294496 208 dbSNP
rs1418523837 208 dbSNP
rs1295767038 215 dbSNP
rs1001513118 217 dbSNP
rs1432027619 218 dbSNP
rs893190256 222 dbSNP
rs905783828 223 dbSNP
rs543315840 228 dbSNP
rs1014584972 231 dbSNP
rs1238274055 238 dbSNP
rs148006130 242 dbSNP
rs1054870138 243 dbSNP
rs1047543585 249 dbSNP
rs937316359 250 dbSNP
rs1336372267 251 dbSNP
rs930420699 252 dbSNP
rs376291750 253 dbSNP
rs1243558797 260 dbSNP
rs367918324 265 dbSNP
rs1156467224 266 dbSNP
rs1038682277 267 dbSNP
rs1400846475 268 dbSNP
rs1045034263 274 dbSNP
rs111814913 278 dbSNP
rs541936374 280 dbSNP
rs1337748505 281 dbSNP
rs780351831 281 dbSNP
rs1159195558 282 dbSNP
rs1421372171 283 dbSNP
rs1444749710 285 dbSNP
rs917776274 290 dbSNP
rs1374130723 292 dbSNP
rs1165385496 293 dbSNP
rs112060190 296 dbSNP
rs987103027 296 dbSNP
rs559476710 312 dbSNP
rs919648264 320 dbSNP
rs1457208339 334 dbSNP
rs1179213081 335 dbSNP
rs146940870 340 dbSNP
rs1470171111 341 dbSNP
rs1190083872 345 dbSNP
rs1472990705 352 dbSNP
rs988953948 355 dbSNP
rs963779982 356 dbSNP
rs1400021923 359 dbSNP
rs1033061024 365 dbSNP
rs778020005 366 dbSNP
rs111618038 371 dbSNP
rs1355375488 373 dbSNP
rs141133957 385 dbSNP
rs1008456980 387 dbSNP
rs1489530874 387 dbSNP
rs1282748025 389 dbSNP
rs773411658 392 dbSNP
rs186272233 395 dbSNP
rs1223623774 397 dbSNP
rs1347476397 401 dbSNP
rs970123854 403 dbSNP
rs772557247 404 dbSNP
rs1024719645 408 dbSNP
rs748465557 412 dbSNP
rs1274894341 414 dbSNP
rs1437999317 430 dbSNP
rs1010325631 432 dbSNP
rs1014202852 432 dbSNP
rs772154561 436 dbSNP
rs1200764866 438 dbSNP
rs994602571 439 dbSNP
rs1474611391 448 dbSNP
rs1169963286 452 dbSNP
rs577312189 459 dbSNP
rs1298842523 460 dbSNP
rs1002014464 464 dbSNP
rs905890284 470 dbSNP
rs748453879 471 dbSNP
rs559251645 472 dbSNP
rs896370657 475 dbSNP
rs890154300 476 dbSNP
rs779280083 478 dbSNP
rs1339834689 480 dbSNP
rs537754233 481 dbSNP
rs929865402 482 dbSNP
rs1222638927 488 dbSNP
rs913456245 490 dbSNP
rs1445726741 494 dbSNP
rs1195969702 497 dbSNP
rs1373992037 500 dbSNP
rs1474636683 503 dbSNP
rs988985133 505 dbSNP
rs749770960 507 dbSNP
rs919747028 507 dbSNP
rs201191281 509 dbSNP
rs765268936 513 dbSNP
rs973878440 517 dbSNP
rs1158077204 518 dbSNP
rs1358720380 521 dbSNP
rs1380392852 528 dbSNP
rs1320282841 545 dbSNP
rs183805054 546 dbSNP
rs1447074826 547 dbSNP
rs1312416959 548 dbSNP
rs1361102073 548 dbSNP
rs3810853 557 dbSNP
rs535951706 558 dbSNP
rs970536888 568 dbSNP
rs1263110737 569 dbSNP
rs1442174828 573 dbSNP
rs1024335562 576 dbSNP
rs1245383929 577 dbSNP
rs1178265255 578 dbSNP
rs1240934844 578 dbSNP
rs1455462619 585 dbSNP
rs1160200170 588 dbSNP
rs986400409 589 dbSNP
rs1385626779 590 dbSNP
rs912328563 595 dbSNP
rs191447694 616 dbSNP
rs1026147277 617 dbSNP
rs994708908 618 dbSNP
rs1308155066 634 dbSNP
rs1292388834 640 dbSNP
rs963214009 641 dbSNP
rs1240611181 646 dbSNP
rs116533706 647 dbSNP
rs370535697 649 dbSNP
rs1265317923 654 dbSNP
rs957593228 657 dbSNP
rs866240106 660 dbSNP
rs1220582868 661 dbSNP
rs1001647327 664 dbSNP
rs1051452016 665 dbSNP
rs1182565321 666 dbSNP
rs1377162258 673 dbSNP
rs905916084 677 dbSNP
rs781129108 678 dbSNP
rs186358166 679 dbSNP
rs1297220474 680 dbSNP
rs1323591880 682 dbSNP
rs886438085 685 dbSNP
rs1400628617 687 dbSNP
rs1172369005 689 dbSNP
rs1047046986 694 dbSNP
rs549630545 695 dbSNP
rs1307020560 700 dbSNP
rs1476590402 706 dbSNP
rs1222220672 715 dbSNP
rs1418099741 716 dbSNP
rs55861694 718 dbSNP
rs1198452661 719 dbSNP
rs147758592 720 dbSNP
rs114102032 721 dbSNP
rs910936100 725 dbSNP
rs1266676648 726 dbSNP
rs538032810 729 dbSNP
rs1489898799 731 dbSNP
rs992798676 736 dbSNP
rs1431409557 742 dbSNP
rs950757243 745 dbSNP
rs1169422088 747 dbSNP
rs1192204267 749 dbSNP
rs933694787 749 dbSNP
rs912889893 750 dbSNP
rs919250359 751 dbSNP
rs115089240 752 dbSNP
rs752459070 754 dbSNP
rs541544947 755 dbSNP
rs980644959 758 dbSNP
rs970134059 760 dbSNP
rs1346647504 764 dbSNP
rs1293806554 772 dbSNP
rs190853870 775 dbSNP
rs377120906 776 dbSNP
rs886469006 787 dbSNP
rs1058508 788 dbSNP
rs1269723794 790 dbSNP
rs1369702859 792 dbSNP
rs953880679 799 dbSNP
rs543740020 804 dbSNP
rs1185868611 810 dbSNP
rs1259398441 813 dbSNP
rs1377346623 813 dbSNP
rs576709633 827 dbSNP
rs898377394 831 dbSNP
rs1038213090 834 dbSNP
rs1170685119 839 dbSNP
rs554857446 840 dbSNP
rs536899176 841 dbSNP
rs1422390752 845 dbSNP
rs1164878630 852 dbSNP
rs572557072 853 dbSNP
rs1430560143 854 dbSNP
rs1287698382 855 dbSNP
rs1364505037 856 dbSNP
rs1383169503 865 dbSNP
rs1007094694 867 dbSNP
rs889613318 868 dbSNP
rs1292511334 869 dbSNP
rs1460096199 876 dbSNP
rs1050833014 878 dbSNP
rs1258945687 880 dbSNP
rs933727329 882 dbSNP
rs553411570 891 dbSNP
rs35973966 895 dbSNP
rs1186846756 899 dbSNP
rs1053172228 900 dbSNP
rs538363332 901 dbSNP
rs1044584079 902 dbSNP
rs936276556 903 dbSNP
rs570882166 904 dbSNP
rs1347425027 909 dbSNP
rs1479756662 910 dbSNP
rs929377066 917 dbSNP
rs1381046149 918 dbSNP
rs1232498423 921 dbSNP
rs1316070707 922 dbSNP
rs549399678 923 dbSNP
rs1372677302 926 dbSNP
rs980378075 927 dbSNP
rs537738794 928 dbSNP
rs1318600353 932 dbSNP
rs1209287404 935 dbSNP
rs1018029933 936 dbSNP
rs1459865460 936 dbSNP
rs1205158416 937 dbSNP
rs963339276 938 dbSNP
rs15627 940 dbSNP
rs985983655 944 dbSNP
rs1420134368 945 dbSNP
rs1176426623 954 dbSNP
rs1233405181 954 dbSNP
rs1354160260 957 dbSNP
rs1404352892 958 dbSNP
rs1311133798 960 dbSNP
rs1471190467 960 dbSNP
rs954742635 963 dbSNP
rs1030158439 964 dbSNP
rs1372214919 965 dbSNP
rs777232732 966 dbSNP
rs1303031731 970 dbSNP
rs567898218 974 dbSNP
rs1373077047 975 dbSNP
rs1225157101 976 dbSNP
rs1436808779 976 dbSNP
rs545905264 976 dbSNP
rs987917894 976 dbSNP
rs1172331408 977 dbSNP
rs956426052 978 dbSNP
rs1481725597 979 dbSNP
rs992937029 982 dbSNP
rs147120312 983 dbSNP
rs1331206390 986 dbSNP
rs1000507614 987 dbSNP
rs1381350077 992 dbSNP
rs1343513516 995 dbSNP
rs1406713235 997 dbSNP
rs950755204 1000 dbSNP
rs112700117 1004 dbSNP
rs995211601 1010 dbSNP
rs1338582012 1011 dbSNP
rs1023601730 1012 dbSNP
rs1013159179 1015 dbSNP
rs1221041567 1016 dbSNP
rs1407620636 1016 dbSNP
rs1266175087 1019 dbSNP
rs896000007 1023 dbSNP
rs185253127 1028 dbSNP
rs1241883779 1029 dbSNP
rs527439122 1030 dbSNP
rs1006751948 1031 dbSNP
rs556079682 1032 dbSNP
rs1161690405 1037 dbSNP
rs1367537358 1044 dbSNP
rs1324193148 1049 dbSNP
rs1325620144 1054 dbSNP
rs910549744 1055 dbSNP
rs547880862 1059 dbSNP
rs532684701 1060 dbSNP
rs997906870 1061 dbSNP
rs986488268 1063 dbSNP
rs933240397 1064 dbSNP
rs1210941928 1083 dbSNP
rs761285743 1089 dbSNP
rs773427202 1090 dbSNP
rs935706117 1091 dbSNP
rs956458431 1092 dbSNP
rs1249050891 1095 dbSNP
rs1444166344 1102 dbSNP
rs1353027420 1106 dbSNP
rs1182053308 1109 dbSNP
rs1387150918 1111 dbSNP
rs1032062770 1116 dbSNP
rs925634586 1118 dbSNP
rs565266502 1120 dbSNP
rs374907162 1121 dbSNP
rs1414733707 1124 dbSNP
rs1361784171 1125 dbSNP
rs948932089 1126 dbSNP
rs917440531 1127 dbSNP
rs180778390 1128 dbSNP
rs1312533796 1145 dbSNP
rs950784811 1150 dbSNP
rs561583617 1158 dbSNP
rs1035833268 1159 dbSNP
rs748316004 1161 dbSNP
rs111898586 1162 dbSNP
rs1415802451 1168 dbSNP
rs572271853 1178 dbSNP
rs867515196 1179 dbSNP
rs1017589687 1181 dbSNP
rs1187375963 1181 dbSNP
rs1362153036 1188 dbSNP
rs1478169762 1188 dbSNP
rs1006784441 1192 dbSNP
rs1037789239 1197 dbSNP
rs539511551 1198 dbSNP
rs953937638 1201 dbSNP
rs1029459790 1202 dbSNP
rs997937967 1205 dbSNP
rs1403854213 1208 dbSNP
rs891625851 1209 dbSNP
rs1179849255 1217 dbSNP
rs189975512 1222 dbSNP
rs1333548894 1225 dbSNP
rs933252820 1234 dbSNP
rs999935493 1242 dbSNP
rs1241793228 1244 dbSNP
rs904211930 1246 dbSNP
rs1044044808 1251 dbSNP
rs1222024936 1257 dbSNP
rs1265417754 1259 dbSNP
rs115122623 1260 dbSNP
rs896037139 1263 dbSNP
rs925106602 1267 dbSNP
rs4975573 1270 dbSNP
rs184601040 1272 dbSNP
rs919423129 1273 dbSNP
rs537800779 1276 dbSNP
rs749401237 1278 dbSNP
rs916248364 1282 dbSNP
rs1379167447 1285 dbSNP
rs1384744505 1289 dbSNP
rs973923415 1292 dbSNP
rs780146993 1293 dbSNP
rs1411169989 1295 dbSNP
rs1392608099 1296 dbSNP
rs960287565 1298 dbSNP
rs942106620 1300 dbSNP
rs1345385001 1301 dbSNP
rs1403656498 1304 dbSNP
rs1303781501 1314 dbSNP
rs1313218291 1315 dbSNP
rs910558683 1318 dbSNP
rs993706615 1318 dbSNP
rs962218973 1319 dbSNP
rs118075009 1321 dbSNP
rs953968553 1324 dbSNP
rs1490149129 1331 dbSNP
rs182056707 1331 dbSNP
rs1374802341 1332 dbSNP
rs1433610258 1333 dbSNP
rs377293292 1335 dbSNP
rs1370947724 1337 dbSNP
rs373810211 1339 dbSNP
rs1168611191 1346 dbSNP
rs956095746 1350 dbSNP
rs747021761 1353 dbSNP
rs1295858224 1358 dbSNP
rs533863516 1367 dbSNP
rs1382048504 1370 dbSNP
rs997494660 1372 dbSNP
rs1272220016 1378 dbSNP
rs901766781 1382 dbSNP
rs566646933 1383 dbSNP
rs1357448354 1391 dbSNP
rs1000372619 1392 dbSNP
rs904242303 1400 dbSNP
rs986672943 1402 dbSNP
rs775386058 1403 dbSNP
rs935220440 1403 dbSNP
rs61567240 1404 dbSNP
rs532645007 1405 dbSNP
rs947807481 1414 dbSNP
rs916297620 1416 dbSNP
rs1325488281 1422 dbSNP
rs1384056716 1435 dbSNP
rs895480571 1437 dbSNP
rs1447704974 1442 dbSNP
rs992236906 1445 dbSNP
rs1350933378 1450 dbSNP
rs1398767275 1455 dbSNP
rs1287423610 1456 dbSNP
rs1057414605 1457 dbSNP
rs571818649 1458 dbSNP
rs898010899 1459 dbSNP
rs972319230 1463 dbSNP
rs962251869 1467 dbSNP
rs1230065966 1480 dbSNP
rs56368594 1484 dbSNP
rs1006360677 1486 dbSNP
rs1309456095 1491 dbSNP
rs1214993730 1493 dbSNP
rs1266008461 1498 dbSNP
rs1466130163 1501 dbSNP
rs1208937786 1502 dbSNP
rs1242187139 1506 dbSNP
rs1459724903 1507 dbSNP
rs1183047810 1509 dbSNP
rs942118926 1513 dbSNP
rs1418936340 1529 dbSNP
rs910600339 1532 dbSNP
rs1252073620 1533 dbSNP
rs74431452 1545 dbSNP
rs1336522926 1546 dbSNP
rs561142792 1549 dbSNP
rs933359963 1553 dbSNP
rs923262323 1567 dbSNP
rs543279169 1568 dbSNP
rs1194776244 1569 dbSNP
rs1223136856 1571 dbSNP
rs1052414505 1572 dbSNP
rs1330907094 1574 dbSNP
rs1228732978 1577 dbSNP
rs528006242 1583 dbSNP
rs560303940 1585 dbSNP
rs1440281542 1590 dbSNP
rs1211802614 1594 dbSNP
rs1237545300 1600 dbSNP
rs1237067125 1602 dbSNP
rs903740773 1606 dbSNP
rs1031936070 1611 dbSNP
rs1303076379 1612 dbSNP
rs1427649118 1614 dbSNP
rs1416381315 1619 dbSNP
rs1443231912 1622 dbSNP
rs752235903 1624 dbSNP
rs545242714 1629 dbSNP
rs1022759115 1630 dbSNP
rs1309967505 1634 dbSNP
rs1012661248 1637 dbSNP
rs1352201797 1638 dbSNP
rs1410370225 1646 dbSNP
rs577817801 1653 dbSNP
rs1220584311 1654 dbSNP
rs1278943700 1655 dbSNP
rs959720286 1669 dbSNP
rs1202348537 1673 dbSNP
rs556181583 1675 dbSNP
rs754500489 1676 dbSNP
rs1199418233 1679 dbSNP
rs898045692 1683 dbSNP
rs1479239556 1686 dbSNP
rs1038279985 1689 dbSNP
rs1432742682 1691 dbSNP
rs1006431940 1694 dbSNP
rs940959924 1701 dbSNP
rs889277539 1704 dbSNP
rs1170501015 1705 dbSNP
rs1159085035 1706 dbSNP
rs909433152 1711 dbSNP
rs1430325556 1712 dbSNP
rs1302533727 1714 dbSNP
rs117441955 1728 dbSNP
rs933389459 1729 dbSNP
rs1360770745 1734 dbSNP
rs1180626261 1735 dbSNP
rs753371458 1737 dbSNP
rs1342334118 1739 dbSNP
rs1058542 1760 dbSNP
rs923293582 1767 dbSNP
rs1453862974 1768 dbSNP
rs1258917472 1769 dbSNP
rs1213676277 1774 dbSNP
rs375183303 1775 dbSNP
rs3205441 1777 dbSNP
rs149819411 1784 dbSNP
rs1190824176 1785 dbSNP
rs1390850931 1790 dbSNP
rs766036411 1794 dbSNP
rs1161568101 1796 dbSNP
rs1484948318 1798 dbSNP
rs1064457 1803 dbSNP
rs1388429153 1807 dbSNP
rs1407029857 1815 dbSNP
rs1323893257 1816 dbSNP
rs934580546 1817 dbSNP
rs1299422409 1818 dbSNP
rs1232937145 1834 dbSNP
rs3205446 1835 dbSNP
rs533419023 1840 dbSNP
rs12332611 1841 dbSNP
rs1229401495 1849 dbSNP
rs903771045 1856 dbSNP
rs979084492 1857 dbSNP
rs113560520 1861 dbSNP
rs371406741 1861 dbSNP
rs1248924344 1866 dbSNP
rs1461055007 1869 dbSNP
rs773838413 1874 dbSNP
rs915732356 1875 dbSNP
rs534067477 1881 dbSNP
rs991257884 1882 dbSNP
rs959752613 1883 dbSNP
rs1035367420 1888 dbSNP
rs1238520272 1891 dbSNP
rs1388860002 1895 dbSNP
rs1056208308 1901 dbSNP
rs547504741 1903 dbSNP
rs993141258 1904 dbSNP
rs1246151156 1906 dbSNP
rs939122606 1908 dbSNP
rs962014493 1911 dbSNP
rs1016552135 1912 dbSNP
rs1323017752 1916 dbSNP
rs1382434745 1917 dbSNP
rs1258330959 1918 dbSNP
rs1443123050 1921 dbSNP
rs1373333407 1923 dbSNP
rs1006873873 1924 dbSNP
rs1188124170 1925 dbSNP
rs1250929977 1930 dbSNP
rs1471584294 1938 dbSNP
rs889307085 1942 dbSNP
rs1170508873 1944 dbSNP
rs1465231725 1944 dbSNP
rs372610037 1944 dbSNP
rs985097307 1946 dbSNP
rs572214362 1947 dbSNP
rs767714722 1951 dbSNP
rs1289369003 1953 dbSNP
rs1345337242 1957 dbSNP
rs546348990 1960 dbSNP
rs1258024825 1961 dbSNP
rs1050530216 1962 dbSNP
rs550739460 1964 dbSNP
rs576989614 1967 dbSNP
rs976216906 1970 dbSNP
rs901902395 1971 dbSNP
rs1031050394 1974 dbSNP
rs978167766 1975 dbSNP
rs1196269534 1976 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BACD3
Disease MIMAT0027413
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020025. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020025
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD3 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000264930.5 | 3UTR | GCCUACGCUCCGGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
179 hsa-miR-6756-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT069654 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT069666 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT123234 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT150220 MIDN midnolin 2 2
MIRT246309 HIST2H2AA3 histone cluster 2 H2A family member a3 2 2
MIRT246321 HIST2H2AA4 histone cluster 2 H2A family member a4 2 2
MIRT338417 ANKRD52 ankyrin repeat domain 52 2 2
MIRT338804 STMN1 stathmin 1 2 2
MIRT345117 ATXN7L3 ataxin 7 like 3 2 2
MIRT360222 SOX4 SRY-box 4 2 2
MIRT360816 GLO1 glyoxalase I 2 2
MIRT384636 SP1 Sp1 transcription factor 2 2
MIRT446400 SNX1 sorting nexin 1 2 2
MIRT447475 ATP10D ATPase phospholipid transporting 10D (putative) 2 2
MIRT477796 E2F2 E2F transcription factor 2 2 2
MIRT479381 CELF1 CUGBP Elav-like family member 1 2 6
MIRT495240 RHEBL1 RHEB like 1 2 2
MIRT495313 GDF11 growth differentiation factor 11 2 2
MIRT495953 SLC12A7 solute carrier family 12 member 7 2 2
MIRT496425 ACTRT3 actin related protein T3 2 2
MIRT504108 FLOT1 flotillin 1 2 2
MIRT506765 KMT2D lysine methyltransferase 2D 2 2
MIRT520355 UBE2K ubiquitin conjugating enzyme E2 K 2 4
MIRT520794 TBRG1 transforming growth factor beta regulator 1 2 4
MIRT529620 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT532385 UMPS uridine monophosphate synthetase 2 2
MIRT533386 UBA6 ubiquitin like modifier activating enzyme 6 2 2
MIRT533944 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 2
MIRT537069 GPR176 G protein-coupled receptor 176 2 2
MIRT556424 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT560755 ARMC10 armadillo repeat containing 10 2 2
MIRT566476 PDCD4 programmed cell death 4 2 2
MIRT567249 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT570547 PRMT7 protein arginine methyltransferase 7 2 2
MIRT572756 FAM204A family with sequence similarity 204 member A 2 2
MIRT573088 APLN apelin 2 2
MIRT573236 GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2 2
MIRT575503 Ankle1 ankyrin repeat and LEM domain containing 1 2 6
MIRT606952 ANKLE1 ankyrin repeat and LEM domain containing 1 2 9
MIRT609247 SERPINA4 serpin family A member 4 2 2
MIRT609348 ZNF664 zinc finger protein 664 2 2
MIRT609475 LSAMP limbic system-associated membrane protein 2 2
MIRT610253 LRRC47 leucine rich repeat containing 47 2 2
MIRT610404 RXRB retinoid X receptor beta 2 2
MIRT612091 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT612222 EPX eosinophil peroxidase 2 4
MIRT613599 SCN1A sodium voltage-gated channel alpha subunit 1 2 2
MIRT614425 TAZ tafazzin 2 2
MIRT615143 ACVR2B activin A receptor type 2B 2 2
MIRT616784 CD44 CD44 molecule (Indian blood group) 2 2
MIRT619132 MCOLN3 mucolipin 3 2 2
MIRT619309 KIRREL kirre like nephrin family adhesion molecule 1 2 2
MIRT619988 ZSCAN22 zinc finger and SCAN domain containing 22 2 2
MIRT620196 VN1R1 vomeronasal 1 receptor 1 2 2
MIRT620467 CERS6 ceramide synthase 6 2 2
MIRT621247 QTRT1 queuine tRNA-ribosyltransferase catalytic subunit 1 2 2
MIRT623538 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT624218 DCAF5 DDB1 and CUL4 associated factor 5 2 2
MIRT624497 CABP4 calcium binding protein 4 2 2
MIRT627849 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT628261 EFCAB14 EF-hand calcium binding domain 14 2 2
MIRT637347 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT640074 KCNMB4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 2 2
MIRT640578 MYO5A myosin VA 2 2
MIRT641444 PELO pelota mRNA surveillance and ribosome rescue factor 2 2
MIRT641881 SND1 staphylococcal nuclease and tudor domain containing 1 2 2
MIRT642422 CILP2 cartilage intermediate layer protein 2 2 2
MIRT642834 KIAA0319 KIAA0319 2 2
MIRT643516 CCDC115 coiled-coil domain containing 115 2 2
MIRT643624 YY2 YY2 transcription factor 2 2
MIRT644202 LAT2 linker for activation of T-cells family member 2 2 2
MIRT644212 CBS cystathionine-beta-synthase 2 2
MIRT644364 NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 2 2
MIRT645177 NOL9 nucleolar protein 9 2 4
MIRT645371 C9orf47 chromosome 9 open reading frame 47 2 2
MIRT646254 PRSS38 protease, serine 38 2 2
MIRT646543 KLK2 kallikrein related peptidase 2 2 2
MIRT646577 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT646640 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT647119 ZNF446 zinc finger protein 446 2 2
MIRT647168 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT647416 SSTR3 somatostatin receptor 3 2 2
MIRT647432 ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2 2
MIRT647515 HSPA5 heat shock protein family A (Hsp70) member 5 2 2
MIRT647583 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT648148 SUCLG2 succinate-CoA ligase GDP-forming beta subunit 2 2
MIRT648646 ZNF562 zinc finger protein 562 2 2
MIRT649579 PALD1 phosphatase domain containing, paladin 1 2 2
MIRT649721 TWSG1 twisted gastrulation BMP signaling modulator 1 2 2
MIRT649792 LPCAT3 lysophosphatidylcholine acyltransferase 3 2 2
MIRT649807 GALC galactosylceramidase 2 2
MIRT649957 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT650130 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT650481 UFM1 ubiquitin fold modifier 1 2 2
MIRT650730 TNFSF8 TNF superfamily member 8 2 2
MIRT650966 STARD3NL STARD3 N-terminal like 2 4
MIRT651010 ZNF740 zinc finger protein 740 2 2
MIRT651122 ZNF48 zinc finger protein 48 2 2
MIRT651301 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT651827 USP49 ubiquitin specific peptidase 49 2 2
MIRT651969 UBE2J1 ubiquitin conjugating enzyme E2 J1 2 2
MIRT652028 TTPAL alpha tocopherol transfer protein like 2 2
MIRT652286 TNS4 tensin 4 2 2
MIRT652712 THBS2 thrombospondin 2 2 2
MIRT652790 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT653333 SMIM18 small integral membrane protein 18 2 2
MIRT653866 SHANK2 SH3 and multiple ankyrin repeat domains 2 2 2
MIRT654046 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT654802 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT654818 PPP3R1 protein phosphatase 3 regulatory subunit B, alpha 2 2
MIRT654955 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT655165 PHF20L1 PHD finger protein 20 like 1 2 2
MIRT655397 PANK3 pantothenate kinase 3 2 2
MIRT655422 PAN2 PAN2 poly(A) specific ribonuclease subunit 2 2
MIRT655656 NUPL2 nucleoporin like 2 2 2
MIRT655682 NUMBL NUMB like, endocytic adaptor protein 2 2
MIRT655713 MLF2 myeloid leukemia factor 2 2 2
MIRT655915 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2 2
MIRT655955 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT656198 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT656374 MDFI MyoD family inhibitor 2 2
MIRT656742 LMBR1L limb development membrane protein 1 like 2 2
MIRT656763 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT656832 KLF8 Kruppel like factor 8 2 2
MIRT657165 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT657744 GNG12 G protein subunit gamma 12 2 2
MIRT657921 GCC1 GRIP and coiled-coil domain containing 1 2 2
MIRT658201 FBXO44 F-box protein 44 2 2
MIRT658418 FAM199X family with sequence similarity 199, X-linked 2 2
MIRT658843 DUSP22 dual specificity phosphatase 22 2 2
MIRT659208 CYBB cytochrome b-245 beta chain 2 2
MIRT659223 CXXC5 CXXC finger protein 5 2 2
MIRT660045 C15orf61 chromosome 15 open reading frame 61 2 2
MIRT660267 BLOC1S5 biogenesis of lysosomal organelles complex 1 subunit 5 2 4
MIRT660575 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT660719 AMER1 APC membrane recruitment protein 1 2 2
MIRT660929 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT661580 EPHX2 epoxide hydrolase 2 2 2
MIRT662151 IPO11 importin 11 2 2
MIRT662366 TADA2A transcriptional adaptor 2A 2 2
MIRT663317 TECPR2 tectonin beta-propeller repeat containing 2 2 2
MIRT663816 RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2 2
MIRT666621 REEP2 receptor accessory protein 2 2 2
MIRT667798 JHDM1D lysine demethylase 7A 1 1
MIRT668598 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT668653 DYM dymeclin 2 2
MIRT668761 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT669375 BAHD1 bromo adjacent homology domain containing 1 2 2
MIRT687529 NASP nuclear autoantigenic sperm protein 2 2
MIRT693229 KIAA0907 KIAA0907 2 4
MIRT697711 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT700569 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT710933 ING5 inhibitor of growth family member 5 2 2
MIRT710974 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711826 MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2 2
MIRT712709 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT712732 NCAPG2 non-SMC condensin II complex subunit G2 2 2
MIRT713034 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT714200 TRAF7 TNF receptor associated factor 7 2 2
MIRT714869 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT715247 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT715922 ACVRL1 activin A receptor like type 1 2 2
MIRT716239 METTL21A methyltransferase like 21A 2 2
MIRT716974 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT718949 CLMN calmin 2 2
MIRT719575 TYRO3 TYRO3 protein tyrosine kinase 2 2
MIRT721631 DNAJC30 DnaJ heat shock protein family (Hsp40) member C30 2 2
MIRT721830 POU6F1 POU class 6 homeobox 1 2 2
MIRT722293 DMRTB1 DMRT like family B with proline rich C-terminal 1 2 2
MIRT722639 C8A complement C8 alpha chain 2 2
MIRT722898 LRRC20 leucine rich repeat containing 20 2 2
MIRT723073 GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 2 2
MIRT723392 CALN1 calneuron 1 2 2
MIRT724183 GDF6 growth differentiation factor 6 2 2
MIRT724249 TENM4 teneurin transmembrane protein 4 2 2
MIRT724369 ASGR1 asialoglycoprotein receptor 1 2 2
MIRT724514 KLHL5 kelch like family member 5 2 2
MIRT724579 NOTCH2 notch 2 2 2
MIRT724714 CRAMP1L cramped chromatin regulator homolog 1 2 2

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