miRTarBase - #MIRT496408


—
pre-miRNA Information
pre-miRNA hsa-mir-5189   
Genomic Coordinates chr16: 88468918 - 88469031
Description Homo sapiens miR-5189 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5189-5p
Sequence 26| UCUGGGCACAGGCGGAUGGACAGG |49
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1253186568 1 dbSNP
rs1157467955 6 dbSNP
rs1375543253 7 dbSNP
rs188172752 9 dbSNP
rs1214792828 10 dbSNP
rs990027849 13 dbSNP
rs913161946 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PARVB   
Synonyms CGI-56
Description parvin beta
Transcript NM_001003828   
Other Transcripts NM_013327   
Expression
Putative miRNA Targets on PARVB
3'UTR of PARVB
(miRNA target sites are highlighted)		 
>PARVB|NM_001003828|3'UTR
   1 CGGGGGAGCTGTGGATGGTGGCAGGAGTGTCCCAGCAAGAAAGGCGGCATCCGTCTGTGCCCTGTGCCTTTCCAGGGAGC
  81 CAGGCGCCATGGGCTTCTGGTCCAAGCTGTGTTGACTGTCATCCCCACCCCACCCCTACCTCACGCCTGCCCCACCCCCT
 161 GCCTCTTTTGGTTGTTGTTCTTAATCTCCTCTCCATGTAGTTCCCAGTGGGCAAGAGCCTTTGAAAATGCAGGATTCTAA
 241 ACACTCGTGCTTGCGTTTGAAGCCTCGCGTCACTCAGTCGCGTGGGATGATGAGTCCGTTGTTGTCTGCCTTGGCCGAAA
 321 GATGAAAAAAAGCCTGAACCCCAACCCCCAGCTGGTTGAGAGCACCCTGCATTCTGCCTCATGGTGCAGTTAGCGATCAC
 401 AGGCCTTCAGAAGTACAACATCAGCTCAGCAGGAACGCCGGCTCCCCGAGGACCCAGGCTTGACGATTCACCGGGGATCT
 481 CCTGGGCTGGGCTCTCCTTGGAAGTGAGGCCTTTTATTAAAAATAAAAGGGTTTTGCAGTTTGAAAAACTTTAAAAAAAA
 561 AAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggacagGUAGGCGGACACGGGUCu 5'
                ||||||:|||||||| | 
Target 5' aggcggCATCCGTCTGTGCCCTGt 3'
 42 - 65 154.00 -31.70
2 
miRNA  3' ggACAGG-UAGGCGGA-CACGGGUCu 5'
            | |||  ||| : | || ||||| 
Target 5' aaTCTCCTCTCCATGTAGTTCCCAGt 3'
 183 - 208 126.00 -18.90
3 
miRNA  3' ggacAGGUAG-GCGGACACGGGucu 5'
              | | || ||||  |||||   
Target 5' ccccTACCTCACGCC--TGCCCcac 3'
 133 - 155 116.00 -21.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30112517 2 COSMIC
COSN31505137 9 COSMIC
COSN30509797 33 COSMIC
COSN31493862 44 COSMIC
COSN31518055 46 COSMIC
COSN28201249 64 COSMIC
COSN30626989 110 COSMIC
COSN6423283 128 COSMIC
COSN31959852 440 COSMIC
COSN1899960 632 COSMIC
COSN14665438 1092 COSMIC
COSN14664802 1119 COSMIC
COSN5993427 1197 COSMIC
COSN5456236 1198 COSMIC
COSN5456238 1215 COSMIC
COSN28957269 1345 COSMIC
COSN25473453 1436 COSMIC
COSN15986884 1630 COSMIC
COSN20710861 1798 COSMIC
COSN8019788 1798 COSMIC
COSN5771576 1984 COSMIC
COSN16880410 2344 COSMIC
COSN25643323 2547 COSMIC
COSN20210641 2597 COSMIC
COSN16662714 2616 COSMIC
COSN8019789 2965 COSMIC
COSN27542688 3039 COSMIC
COSN24328492 3180 COSMIC
COSN15680242 3201 COSMIC
COSN8011131 3314 COSMIC
COSN20127969 3639 COSMIC
COSN28101310 3642 COSMIC
COSN8997486 3831 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs778390496 1 dbSNP
rs202107553 2 dbSNP
rs771080850 3 dbSNP
rs1331173417 5 dbSNP
rs1438245869 6 dbSNP
rs774498501 7 dbSNP
rs1365982838 10 dbSNP
rs771864329 17 dbSNP
rs746006153 28 dbSNP
rs1320554494 33 dbSNP
rs368402280 37 dbSNP
rs1196836694 39 dbSNP
rs1272466835 41 dbSNP
rs918566518 42 dbSNP
rs775626083 43 dbSNP
rs1220980888 46 dbSNP
rs761639539 46 dbSNP
rs765049585 47 dbSNP
rs544472319 53 dbSNP
rs183589736 54 dbSNP
rs1465095639 57 dbSNP
rs1289441258 60 dbSNP
rs952816579 62 dbSNP
rs984152459 64 dbSNP
rs112947583 77 dbSNP
rs943197244 80 dbSNP
rs1293420326 86 dbSNP
rs940199149 87 dbSNP
rs1274437028 88 dbSNP
rs546363766 90 dbSNP
rs1166388778 101 dbSNP
rs1455378922 122 dbSNP
rs1410754757 123 dbSNP
rs566335744 125 dbSNP
rs1256300665 127 dbSNP
rs960893289 128 dbSNP
rs1264954135 129 dbSNP
rs992110541 133 dbSNP
rs1002398322 135 dbSNP
rs1206897545 137 dbSNP
rs1275129908 137 dbSNP
rs1465289936 137 dbSNP
rs916227170 138 dbSNP
rs1054823248 140 dbSNP
rs1241671290 141 dbSNP
rs1450179862 142 dbSNP
rs1198654294 144 dbSNP
rs1267691462 145 dbSNP
rs532431244 146 dbSNP
rs1387869461 148 dbSNP
rs1200946268 149 dbSNP
rs1420765455 150 dbSNP
rs1461051760 155 dbSNP
rs923184766 157 dbSNP
rs1168386139 160 dbSNP
rs893483769 160 dbSNP
rs1398575903 161 dbSNP
rs1403369807 164 dbSNP
rs1322698593 165 dbSNP
rs147372761 166 dbSNP
rs569233308 171 dbSNP
rs1175007048 172 dbSNP
rs537881706 174 dbSNP
rs947735910 178 dbSNP
rs1228267800 184 dbSNP
rs1186806250 185 dbSNP
rs1464473135 186 dbSNP
rs1042814848 190 dbSNP
rs1207138370 192 dbSNP
rs906064474 196 dbSNP
rs1234408936 197 dbSNP
rs1296009670 198 dbSNP
rs1228260831 210 dbSNP
rs1008773131 211 dbSNP
rs1318341564 213 dbSNP
rs1018780235 216 dbSNP
rs964650177 218 dbSNP
rs377564723 219 dbSNP
rs1293033784 227 dbSNP
rs1490947738 232 dbSNP
rs763225340 244 dbSNP
rs920499254 245 dbSNP
rs1166670998 246 dbSNP
rs1260636058 246 dbSNP
rs760502897 247 dbSNP
rs896068752 248 dbSNP
rs1374696730 250 dbSNP
rs376115801 250 dbSNP
rs1255711264 255 dbSNP
rs994406279 256 dbSNP
rs1486877026 267 dbSNP
rs80138948 268 dbSNP
rs1046576428 269 dbSNP
rs938172249 270 dbSNP
rs952698914 270 dbSNP
rs1385559397 276 dbSNP
rs984201824 280 dbSNP
rs113398890 281 dbSNP
rs1296522215 282 dbSNP
rs964120576 283 dbSNP
rs1414973683 298 dbSNP
rs974991361 298 dbSNP
rs923100887 299 dbSNP
rs534498799 309 dbSNP
rs1397113027 317 dbSNP
rs988726854 318 dbSNP
rs1018811270 325 dbSNP
rs189504571 328 dbSNP
rs1188950069 333 dbSNP
rs1316361894 334 dbSNP
rs995994580 337 dbSNP
rs369857788 346 dbSNP
rs1483700440 348 dbSNP
rs1275692285 350 dbSNP
rs1197076489 356 dbSNP
rs1353680957 371 dbSNP
rs79210357 371 dbSNP
rs951956888 372 dbSNP
rs753631815 378 dbSNP
rs1205203845 379 dbSNP
rs905614582 380 dbSNP
rs1263147000 391 dbSNP
rs1408971654 395 dbSNP
rs558395609 396 dbSNP
rs937076270 397 dbSNP
rs1015536170 414 dbSNP
rs1390126534 415 dbSNP
rs1057487796 416 dbSNP
rs139097 418 dbSNP
rs567537774 419 dbSNP
rs1470698408 420 dbSNP
rs766245124 421 dbSNP
rs1197396859 429 dbSNP
rs1451475979 436 dbSNP
rs888485954 437 dbSNP
rs1213761524 438 dbSNP
rs1220865696 440 dbSNP
rs764895676 441 dbSNP
rs990966133 442 dbSNP
rs1351163489 445 dbSNP
rs114970265 448 dbSNP
rs964489676 449 dbSNP
rs1326730640 454 dbSNP
rs181809005 455 dbSNP
rs1160529860 456 dbSNP
rs1158741176 459 dbSNP
rs1401451769 464 dbSNP
rs1400075316 465 dbSNP
rs540149740 466 dbSNP
rs1478023059 471 dbSNP
rs559908682 472 dbSNP
rs954558845 473 dbSNP
rs1042102787 474 dbSNP
rs1444991657 477 dbSNP
rs988764029 481 dbSNP
rs757889812 484 dbSNP
rs968586024 497 dbSNP
rs1317909899 498 dbSNP
rs978435906 501 dbSNP
rs1217250458 506 dbSNP
rs150916975 509 dbSNP
rs1236353067 510 dbSNP
rs900213733 511 dbSNP
rs139412394 527 dbSNP
rs1342193473 530 dbSNP
rs1056867871 537 dbSNP
rs1347174816 542 dbSNP
rs41278877 554 dbSNP
rs930156602 568 dbSNP
rs531848353 569 dbSNP
rs1376407956 579 dbSNP
rs1243644623 582 dbSNP
rs1176104716 591 dbSNP
rs1448141234 593 dbSNP
rs1462649333 601 dbSNP
rs1387790465 602 dbSNP
rs1185428484 604 dbSNP
rs1475570074 611 dbSNP
rs1047177421 612 dbSNP
rs888705782 621 dbSNP
rs1005731367 622 dbSNP
rs1280713295 628 dbSNP
rs548242027 629 dbSNP
rs899813558 630 dbSNP
rs998705624 631 dbSNP
rs1295025758 632 dbSNP
rs2235575 652 dbSNP
rs1364403365 688 dbSNP
rs144464970 689 dbSNP
rs1376154714 692 dbSNP
rs1010077865 694 dbSNP
rs1014771810 696 dbSNP
rs879798981 706 dbSNP
rs1469339323 707 dbSNP
rs1177301012 728 dbSNP
rs548155254 736 dbSNP
rs571032883 738 dbSNP
rs961374213 739 dbSNP
rs1420978296 740 dbSNP
rs1408940429 752 dbSNP
rs1179778280 758 dbSNP
rs982046762 759 dbSNP
rs1464575240 761 dbSNP
rs1020097406 765 dbSNP
rs1298106191 769 dbSNP
rs1374456238 772 dbSNP
rs1393520175 773 dbSNP
rs9614356 777 dbSNP
rs1035071446 781 dbSNP
rs1205088297 785 dbSNP
rs771254360 789 dbSNP
rs774753421 800 dbSNP
rs1287745853 807 dbSNP
rs1232905804 822 dbSNP
rs1356334743 831 dbSNP
rs1295563594 832 dbSNP
rs16991609 836 dbSNP
rs1299273379 839 dbSNP
rs1488536411 847 dbSNP
rs1325087428 851 dbSNP
rs1460654955 854 dbSNP
rs915397697 856 dbSNP
rs1166883239 872 dbSNP
rs1471507098 873 dbSNP
rs1249502224 874 dbSNP
rs993025838 876 dbSNP
rs917007686 877 dbSNP
rs35254339 885 dbSNP
rs1480809109 902 dbSNP
rs1047233568 907 dbSNP
rs1213131397 909 dbSNP
rs910030744 913 dbSNP
rs1275247526 921 dbSNP
rs537952065 929 dbSNP
rs941640964 934 dbSNP
rs1039919516 935 dbSNP
rs899868170 937 dbSNP
rs1200220581 938 dbSNP
rs1393647954 941 dbSNP
rs998196188 943 dbSNP
rs1323375286 945 dbSNP
rs1439489497 948 dbSNP
rs554230431 953 dbSNP
rs9614357 954 dbSNP
rs1009630341 964 dbSNP
rs1020151512 965 dbSNP
rs1159559114 971 dbSNP
rs931737717 972 dbSNP
rs968524056 980 dbSNP
rs1193128702 981 dbSNP
rs1000145977 983 dbSNP
rs1468987862 987 dbSNP
rs887637536 991 dbSNP
rs570123793 1007 dbSNP
rs1403888996 1008 dbSNP
rs1004644849 1009 dbSNP
rs1034267463 1010 dbSNP
rs141160794 1012 dbSNP
rs1346805229 1014 dbSNP
rs1212316763 1015 dbSNP
rs1311003572 1016 dbSNP
rs1303359307 1018 dbSNP
rs1294744093 1020 dbSNP
rs371845825 1022 dbSNP
rs1371114645 1023 dbSNP
rs9614358 1035 dbSNP
rs1206358884 1040 dbSNP
rs1036246955 1047 dbSNP
rs1263520092 1053 dbSNP
rs992514113 1055 dbSNP
rs1003541288 1057 dbSNP
rs1172959953 1060 dbSNP
rs1024360740 1061 dbSNP
rs959748200 1064 dbSNP
rs1271344512 1069 dbSNP
rs1186747572 1082 dbSNP
rs1428196923 1086 dbSNP
rs1487334813 1092 dbSNP
rs181533246 1097 dbSNP
rs1022775910 1100 dbSNP
rs982479285 1104 dbSNP
rs1420843176 1110 dbSNP
rs1430866812 1119 dbSNP
rs910083032 1121 dbSNP
rs1305067992 1124 dbSNP
rs770266019 1131 dbSNP
rs1163307609 1132 dbSNP
rs1384926856 1139 dbSNP
rs1425724772 1142 dbSNP
rs867135901 1142 dbSNP
rs941524931 1154 dbSNP
rs1303332098 1168 dbSNP
rs1367105797 1171 dbSNP
rs1428004476 1172 dbSNP
rs1435335804 1176 dbSNP
rs900104600 1177 dbSNP
rs1377179257 1191 dbSNP
rs1287854554 1201 dbSNP
rs976112179 1203 dbSNP
rs1166275960 1211 dbSNP
rs921532556 1212 dbSNP
rs934204834 1213 dbSNP
rs1051117337 1217 dbSNP
rs892452848 1218 dbSNP
rs1216200731 1220 dbSNP
rs186556964 1221 dbSNP
rs1011495220 1222 dbSNP
rs1312843215 1227 dbSNP
rs978220197 1229 dbSNP
rs924192682 1232 dbSNP
rs1043822646 1239 dbSNP
rs966280842 1241 dbSNP
rs545645369 1243 dbSNP
rs200103980 1248 dbSNP
rs1294177210 1251 dbSNP
rs975774853 1252 dbSNP
rs1195692775 1256 dbSNP
rs562725089 1263 dbSNP
rs1215140015 1283 dbSNP
rs921596513 1286 dbSNP
rs368282804 1291 dbSNP
rs1292506502 1302 dbSNP
rs1180583791 1305 dbSNP
rs1357330395 1306 dbSNP
rs1326805665 1309 dbSNP
rs867699269 1313 dbSNP
rs1390694627 1325 dbSNP
rs1048817581 1326 dbSNP
rs1243096260 1326 dbSNP
rs1445597006 1327 dbSNP
rs1438830868 1328 dbSNP
rs1460129218 1328 dbSNP
rs35824884 1328 dbSNP
rs398037303 1328 dbSNP
rs751728651 1328 dbSNP
rs758350806 1328 dbSNP
rs80353476 1328 dbSNP
rs62227758 1329 dbSNP
rs1250697497 1331 dbSNP
rs1165908442 1339 dbSNP
rs1197015313 1344 dbSNP
rs1332284335 1345 dbSNP
rs1386708275 1345 dbSNP
rs1253296087 1346 dbSNP
rs1336693897 1349 dbSNP
rs1238329842 1352 dbSNP
rs1157936358 1356 dbSNP
rs1336269593 1358 dbSNP
rs908923869 1361 dbSNP
rs1438766305 1364 dbSNP
rs1393779949 1370 dbSNP
rs531671753 1371 dbSNP
rs1326855964 1373 dbSNP
rs1345200725 1378 dbSNP
rs1432311606 1380 dbSNP
rs1406244741 1382 dbSNP
rs1334576833 1388 dbSNP
rs1381991454 1395 dbSNP
rs1453088929 1405 dbSNP
rs1316968611 1410 dbSNP
rs548704876 1412 dbSNP
rs1034562402 1416 dbSNP
rs1223363093 1424 dbSNP
rs894404266 1428 dbSNP
rs1036154007 1437 dbSNP
rs1469533713 1438 dbSNP
rs1285255686 1443 dbSNP
rs1281966025 1447 dbSNP
rs1014565325 1449 dbSNP
rs1351361817 1451 dbSNP
rs1023998197 1455 dbSNP
rs907165288 1456 dbSNP
rs1370354279 1466 dbSNP
rs1002730441 1469 dbSNP
rs1201906210 1471 dbSNP
rs951038828 1475 dbSNP
rs1263029629 1478 dbSNP
rs1343640170 1487 dbSNP
rs760460869 1495 dbSNP
rs895164980 1497 dbSNP
rs1387543622 1498 dbSNP
rs1157470743 1499 dbSNP
rs1394023966 1500 dbSNP
rs562059116 1510 dbSNP
rs1236673185 1511 dbSNP
rs2744986 1512 dbSNP
rs1176231318 1513 dbSNP
rs1239976829 1516 dbSNP
rs568311073 1524 dbSNP
rs1022385273 1528 dbSNP
rs975617159 1534 dbSNP
rs74429453 1535 dbSNP
rs776364396 1538 dbSNP
rs934282529 1543 dbSNP
rs1401903102 1548 dbSNP
rs548091128 1554 dbSNP
rs749655781 1555 dbSNP
rs1281197555 1559 dbSNP
rs987444580 1562 dbSNP
rs571120888 1569 dbSNP
rs913936560 1570 dbSNP
rs999733893 1575 dbSNP
rs1470203185 1579 dbSNP
rs1311438920 1584 dbSNP
rs1031166130 1591 dbSNP
rs1338626911 1592 dbSNP
rs1173762464 1594 dbSNP
rs1415718140 1602 dbSNP
rs1416713676 1603 dbSNP
rs1333725115 1606 dbSNP
rs374373348 1609 dbSNP
rs535373740 1610 dbSNP
rs1043707906 1614 dbSNP
rs1185508415 1618 dbSNP
rs386821688 1625 dbSNP
rs190076866 1626 dbSNP
rs139098 1627 dbSNP
rs1221761242 1637 dbSNP
rs1055649750 1638 dbSNP
rs984825890 1649 dbSNP
rs4823198 1650 dbSNP
rs1341721099 1656 dbSNP
rs1387680264 1663 dbSNP
rs143729374 1665 dbSNP
rs1414518429 1666 dbSNP
rs139099 1669 dbSNP
rs1437585703 1670 dbSNP
rs1440576976 1679 dbSNP
rs886815112 1691 dbSNP
rs1003838996 1700 dbSNP
rs1410236569 1701 dbSNP
rs1205706969 1703 dbSNP
rs1162572485 1706 dbSNP
rs1474776196 1707 dbSNP
rs1016523365 1712 dbSNP
rs962449819 1715 dbSNP
rs1232434156 1716 dbSNP
rs139100 1716 dbSNP
rs1196852698 1718 dbSNP
rs1427907800 1720 dbSNP
rs1480494815 1721 dbSNP
rs1459292003 1724 dbSNP
rs1178438257 1725 dbSNP
rs756539672 1727 dbSNP
rs1055726996 1732 dbSNP
rs1222632603 1743 dbSNP
rs894347334 1746 dbSNP
rs1297148460 1755 dbSNP
rs1442255897 1763 dbSNP
rs1401792035 1766 dbSNP
rs1323507771 1775 dbSNP
rs1460539859 1779 dbSNP
rs1394309917 1784 dbSNP
rs1166634867 1789 dbSNP
rs1417298559 1791 dbSNP
rs372149638 1794 dbSNP
rs373290697 1799 dbSNP
rs987107971 1802 dbSNP
rs903972913 1805 dbSNP
rs1251161148 1809 dbSNP
rs1213307585 1812 dbSNP
rs1469074333 1814 dbSNP
rs1356481577 1815 dbSNP
rs145754661 1818 dbSNP
rs966917042 1820 dbSNP
rs979440844 1823 dbSNP
rs546081888 1827 dbSNP
rs1346188880 1830 dbSNP
rs1242888254 1837 dbSNP
rs1378488239 1846 dbSNP
rs1300541535 1859 dbSNP
rs1031068335 1863 dbSNP
rs749639118 1872 dbSNP
rs1295111621 1875 dbSNP
rs757762465 1876 dbSNP
rs9614359 1877 dbSNP
rs1159768869 1891 dbSNP
rs561915734 1893 dbSNP
rs866721948 1896 dbSNP
rs1421373495 1906 dbSNP
rs998059565 1910 dbSNP
rs576232934 1911 dbSNP
rs915780557 1914 dbSNP
rs1029251388 1916 dbSNP
rs1489963114 1917 dbSNP
rs1219745496 1921 dbSNP
rs779261183 1928 dbSNP
rs1269696677 1932 dbSNP
rs1485758735 1935 dbSNP
rs953757353 1935 dbSNP
rs949921527 1947 dbSNP
rs1045503178 1948 dbSNP
rs984510347 1972 dbSNP
rs887036095 1976 dbSNP
rs1200426004 1977 dbSNP
rs541936354 1983 dbSNP
rs1361022273 1985 dbSNP
rs928358025 1990 dbSNP
rs1421504467 1991 dbSNP
rs1168442550 1992 dbSNP
rs562195602 1997 dbSNP
rs1422550104 1998 dbSNP
rs1379391354 1999 dbSNP
rs752492248 1999 dbSNP
rs991691296 1999 dbSNP
rs1428073214 2000 dbSNP
rs915868692 2001 dbSNP
rs898140296 2002 dbSNP
rs1485001256 2004 dbSNP
rs1257473042 2005 dbSNP
rs386821689 2005 dbSNP
rs1491025466 2006 dbSNP
rs59935732 2006 dbSNP
rs67996385 2007 dbSNP
rs758563624 2007 dbSNP
rs996641559 2007 dbSNP
rs1406838316 2008 dbSNP
rs370009985 2027 dbSNP
rs947284429 2037 dbSNP
rs955109927 2038 dbSNP
rs1008820099 2043 dbSNP
rs1357676771 2045 dbSNP
rs1021104976 2047 dbSNP
rs966969180 2050 dbSNP
rs1424567894 2051 dbSNP
rs1173047446 2055 dbSNP
rs541407864 2057 dbSNP
rs1290545886 2067 dbSNP
rs1359795964 2071 dbSNP
rs925304333 2073 dbSNP
rs772341202 2093 dbSNP
rs990959532 2095 dbSNP
rs917997677 2096 dbSNP
rs1480127811 2102 dbSNP
rs544574342 2103 dbSNP
rs1220033948 2112 dbSNP
rs1029568979 2116 dbSNP
rs1211094833 2119 dbSNP
rs1258987794 2130 dbSNP
rs1445924688 2131 dbSNP
rs1193765109 2135 dbSNP
rs1292375840 2136 dbSNP
rs1045557223 2142 dbSNP
rs1437364309 2145 dbSNP
rs889406293 2150 dbSNP
rs1342179463 2151 dbSNP
rs1326986581 2155 dbSNP
rs775389023 2159 dbSNP
rs908360603 2161 dbSNP
rs939966261 2162 dbSNP
rs564472755 2168 dbSNP
rs1016444828 2169 dbSNP
rs563136877 2172 dbSNP
rs550493059 2179 dbSNP
rs570149743 2181 dbSNP
rs1162764025 2188 dbSNP
rs960055535 2200 dbSNP
rs1438562797 2201 dbSNP
rs991370413 2202 dbSNP
rs1049368409 2203 dbSNP
rs915717034 2210 dbSNP
rs1272379491 2217 dbSNP
rs1157049979 2219 dbSNP
rs1210188120 2230 dbSNP
rs185236986 2240 dbSNP
rs1007956917 2241 dbSNP
rs1320822303 2249 dbSNP
rs1377751644 2250 dbSNP
rs1311556347 2252 dbSNP
rs191182044 2257 dbSNP
rs979099600 2258 dbSNP
rs1021155838 2268 dbSNP
rs902669875 2271 dbSNP
rs768562210 2280 dbSNP
rs1033003890 2284 dbSNP
rs1385455047 2285 dbSNP
rs923386099 2289 dbSNP
rs959611762 2296 dbSNP
rs991238445 2298 dbSNP
rs1179958203 2303 dbSNP
rs1452237690 2309 dbSNP
rs933390395 2310 dbSNP
rs1050641656 2313 dbSNP
rs1024948901 2314 dbSNP
rs889299415 2331 dbSNP
rs1288316110 2332 dbSNP
rs547273300 2332 dbSNP
rs1232144373 2337 dbSNP
rs1347196146 2339 dbSNP
rs776595213 2342 dbSNP
rs761595963 2343 dbSNP
rs184120116 2344 dbSNP
rs908415996 2346 dbSNP
rs139101 2349 dbSNP
rs973835578 2354 dbSNP
rs919843387 2359 dbSNP
rs1432353357 2362 dbSNP
rs868686671 2383 dbSNP
rs865959676 2395 dbSNP
rs9614206 2399 dbSNP
rs932555736 2400 dbSNP
rs1022684566 2407 dbSNP
rs767125243 2410 dbSNP
rs1265290628 2412 dbSNP
rs978553636 2416 dbSNP
rs1279337443 2419 dbSNP
rs749951246 2420 dbSNP
rs1269934939 2421 dbSNP
rs1459968418 2422 dbSNP
rs4823199 2428 dbSNP
rs1243453698 2429 dbSNP
rs890777643 2430 dbSNP
rs1311607406 2431 dbSNP
rs1179858972 2436 dbSNP
rs943797255 2437 dbSNP
rs570466716 2447 dbSNP
rs1415872192 2448 dbSNP
rs1454346868 2454 dbSNP
rs1416912759 2457 dbSNP
rs1161548310 2460 dbSNP
rs1478040691 2466 dbSNP
rs1425425170 2469 dbSNP
rs902723888 2472 dbSNP
rs1482882369 2486 dbSNP
rs923248514 2508 dbSNP
rs780459353 2512 dbSNP
rs1050953984 2521 dbSNP
rs1257701334 2526 dbSNP
rs1199444340 2528 dbSNP
rs1320452215 2533 dbSNP
rs539347728 2534 dbSNP
rs895402245 2536 dbSNP
rs375687276 2539 dbSNP
rs1012478929 2541 dbSNP
rs1390053309 2547 dbSNP
rs1025421471 2556 dbSNP
rs749617137 2557 dbSNP
rs762449179 2573 dbSNP
rs1037830523 2575 dbSNP
rs983537540 2587 dbSNP
rs1352215212 2594 dbSNP
rs1014963416 2604 dbSNP
rs1465753962 2606 dbSNP
rs1334849345 2614 dbSNP
rs556449713 2616 dbSNP
rs973888092 2617 dbSNP
rs1183485986 2626 dbSNP
rs1468686160 2635 dbSNP
rs1237574918 2643 dbSNP
rs1199581630 2646 dbSNP
rs148888049 2647 dbSNP
rs1056747846 2650 dbSNP
rs1202911486 2652 dbSNP
rs1221260565 2654 dbSNP
rs1263701782 2657 dbSNP
rs1299754193 2666 dbSNP
rs1484099262 2672 dbSNP
rs932584039 2677 dbSNP
rs1307887025 2678 dbSNP
rs73163818 2679 dbSNP
rs751010090 2680 dbSNP
rs1378623496 2687 dbSNP
rs912247984 2692 dbSNP
rs1457243634 2699 dbSNP
rs1350202914 2702 dbSNP
rs1166838355 2704 dbSNP
rs1012551176 2705 dbSNP
rs1023140464 2708 dbSNP
rs1250077468 2710 dbSNP
rs943683045 2724 dbSNP
rs1441821182 2726 dbSNP
rs968496317 2738 dbSNP
rs759155019 2740 dbSNP
rs1042038197 2741 dbSNP
rs1419959563 2746 dbSNP
rs1489021043 2757 dbSNP
rs902272078 2759 dbSNP
rs779315352 2765 dbSNP
rs1214357692 2768 dbSNP
rs1353597587 2773 dbSNP
rs1000066302 2774 dbSNP
rs1355173459 2779 dbSNP
rs1298769626 2782 dbSNP
rs374105398 2799 dbSNP
rs569283225 2799 dbSNP
rs955966384 2800 dbSNP
rs748356429 2801 dbSNP
rs1295056984 2804 dbSNP
rs555618664 2805 dbSNP
rs976687370 2807 dbSNP
rs1460762739 2814 dbSNP
rs1444602164 2816 dbSNP
rs112562506 2817 dbSNP
rs1219364372 2817 dbSNP
rs1264567227 2817 dbSNP
rs1308578655 2817 dbSNP
rs1298020533 2818 dbSNP
rs922513156 2819 dbSNP
rs1488991968 2821 dbSNP
rs1253674791 2825 dbSNP
rs1312389578 2826 dbSNP
rs1397668976 2826 dbSNP
rs1303189818 2827 dbSNP
rs1339546889 2828 dbSNP
rs1491047899 2828 dbSNP
rs755618510 2828 dbSNP
rs1409983091 2829 dbSNP
rs61575710 2829 dbSNP
rs1309503492 2830 dbSNP
rs760834206 2830 dbSNP
rs767442594 2831 dbSNP
rs1302318370 2832 dbSNP
rs1466785849 2834 dbSNP
rs572524618 2835 dbSNP
rs1222421400 2836 dbSNP
rs986108080 2836 dbSNP
rs910665274 2841 dbSNP
rs1313946489 2852 dbSNP
rs1196475030 2859 dbSNP
rs942111065 2862 dbSNP
rs1224951173 2865 dbSNP
rs973570437 2870 dbSNP
rs1054383981 2873 dbSNP
rs9614207 2878 dbSNP
rs929452294 2879 dbSNP
rs1207514032 2892 dbSNP
rs754453212 2896 dbSNP
rs138119071 2903 dbSNP
rs906753244 2910 dbSNP
rs1004845777 2912 dbSNP
rs1278608121 2914 dbSNP
rs1220453097 2919 dbSNP
rs1014847191 2921 dbSNP
rs533412579 2922 dbSNP
rs963448612 2923 dbSNP
rs1329576574 2929 dbSNP
rs567943487 2932 dbSNP
rs1427193674 2938 dbSNP
rs1027260838 2951 dbSNP
rs953894555 2954 dbSNP
rs1173243552 2961 dbSNP
rs543740051 2965 dbSNP
rs912486292 2966 dbSNP
rs965256088 2971 dbSNP
rs977767113 2994 dbSNP
rs564046788 3007 dbSNP
rs112531523 3010 dbSNP
rs187079448 3012 dbSNP
rs1053530471 3013 dbSNP
rs535789826 3014 dbSNP
rs916770687 3018 dbSNP
rs527345525 3023 dbSNP
rs747085699 3035 dbSNP
rs1293667923 3036 dbSNP
rs1369119946 3038 dbSNP
rs547136674 3039 dbSNP
rs1294810617 3054 dbSNP
rs1353941467 3056 dbSNP
rs1264813986 3060 dbSNP
rs750827819 3069 dbSNP
rs570330645 3078 dbSNP
rs891649669 3079 dbSNP
rs139102 3087 dbSNP
rs1307172117 3088 dbSNP
rs1446384711 3090 dbSNP
rs549524664 3099 dbSNP
rs775300763 3106 dbSNP
rs1403978542 3112 dbSNP
rs1390399295 3115 dbSNP
rs1005065759 3116 dbSNP
rs375131698 3137 dbSNP
rs1239557119 3138 dbSNP
rs1311759874 3138 dbSNP
rs1330958147 3138 dbSNP
rs1354445817 3138 dbSNP
rs1434500733 3138 dbSNP
rs1491222793 3138 dbSNP
rs766430471 3138 dbSNP
rs79839058 3138 dbSNP
rs986570069 3138 dbSNP
rs1324607170 3139 dbSNP
rs1491481554 3139 dbSNP
rs74616239 3140 dbSNP
rs79316133 3159 dbSNP
rs1484950430 3160 dbSNP
rs1186392041 3163 dbSNP
rs569901100 3167 dbSNP
rs1451681282 3169 dbSNP
rs1380312809 3171 dbSNP
rs148022849 3176 dbSNP
rs995365172 3177 dbSNP
rs555558923 3180 dbSNP
rs6006689 3183 dbSNP
rs1490768092 3195 dbSNP
rs1006732667 3196 dbSNP
rs919314560 3199 dbSNP
rs1488662312 3202 dbSNP
rs1288244301 3204 dbSNP
rs1451024348 3208 dbSNP
rs1019430700 3219 dbSNP
rs993010147 3220 dbSNP
rs1338841747 3222 dbSNP
rs965309441 3228 dbSNP
rs1401073346 3231 dbSNP
rs1360685007 3232 dbSNP
rs1319702891 3240 dbSNP
rs977986212 3247 dbSNP
rs374337390 3264 dbSNP
rs535120791 3269 dbSNP
rs747032248 3281 dbSNP
rs1437007229 3296 dbSNP
rs1127721 3297 dbSNP
rs369914728 3303 dbSNP
rs200349574 3313 dbSNP
rs867102275 3314 dbSNP
rs1315176408 3318 dbSNP
rs774350484 3320 dbSNP
rs947765766 3340 dbSNP
rs1269314622 3345 dbSNP
rs111231301 3356 dbSNP
rs928117250 3365 dbSNP
rs1242846712 3369 dbSNP
rs998056548 3374 dbSNP
rs940974493 3376 dbSNP
rs1036564493 3392 dbSNP
rs899211441 3395 dbSNP
rs1342914472 3402 dbSNP
rs1282901490 3403 dbSNP
rs889729168 3404 dbSNP
rs930663777 3405 dbSNP
rs1017240281 3410 dbSNP
rs1050823986 3413 dbSNP
rs889220216 3414 dbSNP
rs1415575634 3415 dbSNP
rs1169663719 3422 dbSNP
rs1416763029 3423 dbSNP
rs1009374861 3424 dbSNP
rs748021401 3437 dbSNP
rs1157824102 3439 dbSNP
rs1389276667 3444 dbSNP
rs1180000373 3453 dbSNP
rs769728046 3458 dbSNP
rs1238060272 3459 dbSNP
rs1334643982 3462 dbSNP
rs900994879 3463 dbSNP
rs1405017795 3465 dbSNP
rs772844701 3476 dbSNP
rs762830946 3479 dbSNP
rs1257876492 3482 dbSNP
rs770458160 3483 dbSNP
rs1026396988 3486 dbSNP
rs1288363909 3487 dbSNP
rs563553990 3490 dbSNP
rs574229122 3493 dbSNP
rs1223279950 3494 dbSNP
rs950795153 3510 dbSNP
rs9614208 3521 dbSNP
rs1030922827 3525 dbSNP
rs1330226484 3528 dbSNP
rs1447280368 3536 dbSNP
rs1356005381 3549 dbSNP
rs958158589 3555 dbSNP
rs989171584 3558 dbSNP
rs1023696930 3560 dbSNP
rs767117593 3564 dbSNP
rs969186672 3568 dbSNP
rs1404692627 3570 dbSNP
rs1414699658 3574 dbSNP
rs1165524426 3577 dbSNP
rs559516816 3578 dbSNP
rs528686900 3579 dbSNP
rs928169484 3581 dbSNP
rs375135832 3582 dbSNP
rs191887731 3584 dbSNP
rs980395852 3591 dbSNP
rs532904610 3598 dbSNP
rs926161104 3609 dbSNP
rs935653409 3612 dbSNP
rs1350805595 3625 dbSNP
rs1479489499 3626 dbSNP
rs555777942 3629 dbSNP
rs1375346775 3631 dbSNP
rs930861234 3636 dbSNP
rs573615688 3638 dbSNP
rs889097827 3639 dbSNP
rs933740975 3644 dbSNP
rs944840310 3646 dbSNP
rs1040477119 3647 dbSNP
rs1414819553 3656 dbSNP
rs1007106290 3660 dbSNP
rs1352557089 3664 dbSNP
rs1423567550 3677 dbSNP
rs1190940176 3678 dbSNP
rs901047207 3679 dbSNP
rs755603203 3681 dbSNP
rs1271715505 3682 dbSNP
rs898415986 3684 dbSNP
rs1030808821 3685 dbSNP
rs1487026511 3688 dbSNP
rs368388201 3692 dbSNP
rs370313510 3704 dbSNP
rs1011219903 3707 dbSNP
rs994832821 3713 dbSNP
rs573942136 3722 dbSNP
rs1026260857 3729 dbSNP
rs969451411 3736 dbSNP
rs140890778 3737 dbSNP
rs1034734407 3740 dbSNP
rs1289499066 3768 dbSNP
rs549346598 3771 dbSNP
rs1221286584 3774 dbSNP
rs146091663 3780 dbSNP
rs868857189 3781 dbSNP
rs534988833 3784 dbSNP
rs752255839 3785 dbSNP
rs930934646 3788 dbSNP
rs1192211265 3792 dbSNP
rs1477775118 3793 dbSNP
rs1437641823 3796 dbSNP
rs1261902261 3800 dbSNP
rs1205174611 3802 dbSNP
rs986777399 3807 dbSNP
rs1252149132 3810 dbSNP
rs553107426 3812 dbSNP
rs1253904276 3814 dbSNP
rs980635333 3816 dbSNP
rs1483730797 3817 dbSNP
rs1196737303 3828 dbSNP
rs1339716254 3830 dbSNP
rs534851915 3831 dbSNP
rs1478281711 3832 dbSNP
rs1376996486 3833 dbSNP
rs944689108 3834 dbSNP
rs557686459 3841 dbSNP
rs1253056937 3842 dbSNP
rs578025010 3843 dbSNP
rs1470424704 3863 dbSNP
rs537152111 3864 dbSNP
rs1174251917 3866 dbSNP
rs183260893 3867 dbSNP
rs1465599955 3888 dbSNP
rs1417077794 3889 dbSNP
rs1195895004 3892 dbSNP
rs924700859 3892 dbSNP
rs1429778192 3894 dbSNP
rs374067468 3904 dbSNP
rs1253458404 3910 dbSNP
rs544897131 3912 dbSNP
rs893616192 3913 dbSNP
rs933627219 3914 dbSNP
rs1403179597 3921 dbSNP
rs1010856754 3928 dbSNP
rs367791874 3930 dbSNP
rs573739063 3932 dbSNP
rs1050878554 3935 dbSNP
rs562995587 3936 dbSNP
rs762807699 3937 dbSNP
rs559652908 3944 dbSNP
rs942588074 3952 dbSNP
rs1038159175 3960 dbSNP
rs905070167 3978 dbSNP
rs1339111156 3984 dbSNP
rs898445585 3985 dbSNP
rs1229652549 3993 dbSNP
rs1397587947 3997 dbSNP
rs1274902052 4000 dbSNP
rs1003170551 4003 dbSNP
rs1162340644 4007 dbSNP
rs1034619983 4012 dbSNP
rs1244616785 4023 dbSNP
rs367599960 4024 dbSNP
rs1457160936 4025 dbSNP
rs1250971373 4031 dbSNP
rs758839712 4034 dbSNP
rs780139549 4048 dbSNP
rs1027852918 4050 dbSNP
rs1024393071 4060 dbSNP
rs1361618551 4074 dbSNP
rs751840175 4076 dbSNP
rs187169615 4077 dbSNP
rs1448615729 4086 dbSNP
rs1336784762 4087 dbSNP
rs1331263847 4097 dbSNP
rs970546888 4099 dbSNP
rs1189053097 4119 dbSNP
rs1390679297 4122 dbSNP
rs1304228762 4134 dbSNP
rs1001746853 4137 dbSNP
rs1392244665 4141 dbSNP
rs1033167230 4142 dbSNP
rs1156533853 4143 dbSNP
rs957633567 4155 dbSNP
rs986440320 4162 dbSNP
rs1162899137 4167 dbSNP
rs910799295 4168 dbSNP
rs1449616604 4169 dbSNP
rs1266617417 4174 dbSNP
rs571365427 4178 dbSNP
rs2294539 4181 dbSNP
rs1223058114 4183 dbSNP
rs966253428 4185 dbSNP
rs138684097 4186 dbSNP
rs142689231 4187 dbSNP
rs924586743 4196 dbSNP
rs575640587 4197 dbSNP
rs533003364 4205 dbSNP
rs934759327 4207 dbSNP
rs942430764 4212 dbSNP
rs147388945 4213 dbSNP
rs915117831 4215 dbSNP
rs563294222 4216 dbSNP
rs919777194 4219 dbSNP
rs533371515 4227 dbSNP
rs1385262739 4230 dbSNP
rs191663351 4232 dbSNP
rs1046972370 4237 dbSNP
rs77048779 4242 dbSNP
rs1044870808 4245 dbSNP
rs905132416 4255 dbSNP
rs754584939 4256 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BACD1
Disease MIMAT0021120
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020024. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020024
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BACD1 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000338758.7 | 3UTR | GCCUAUUUUUUUUUUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
177 hsa-miR-5189-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT142280 DCTN5 dynactin subunit 5 2 4
MIRT455613 SRSF3 serine and arginine rich splicing factor 3 2 2
MIRT458687 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT470847 PLXND1 plexin D1 2 2
MIRT471838 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT475228 IKZF3 IKAROS family zinc finger 3 2 4
MIRT480294 C7orf73 short transmembrane mitochondrial protein 1 2 4
MIRT483509 C10orf76 chromosome 10 open reading frame 76 2 2
MIRT484952 ZBTB34 zinc finger and BTB domain containing 34 2 6
MIRT489295 B4GALNT4 beta-1,4-N-acetyl-galactosaminyltransferase 4 2 4
MIRT490801 PSMD3 proteasome 26S subunit, non-ATPase 3 2 2
MIRT493375 KIAA1614 KIAA1614 2 2
MIRT496408 PARVB parvin beta 2 2
MIRT497267 GRK6 G protein-coupled receptor kinase 6 2 2
MIRT497679 SYNGR1 synaptogyrin 1 2 2
MIRT498222 TLN2 talin 2 2 2
MIRT498313 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT504049 TOMM5 translocase of outer mitochondrial membrane 5 2 2
MIRT516313 F8A2 coagulation factor VIII associated 2 2 2
MIRT516339 F8A3 coagulation factor VIII associated 3 2 2
MIRT517813 UGDH UDP-glucose 6-dehydrogenase 2 6
MIRT518743 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519295 MLH1 mutL homolog 1 2 2
MIRT520387 UBB ubiquitin B 2 4
MIRT525228 DPY19L3 dpy-19 like C-mannosyltransferase 3 2 2
MIRT533147 WNT10A Wnt family member 10A 2 2
MIRT533544 TPR translocated promoter region, nuclear basket protein 2 2
MIRT533684 TMEM86A transmembrane protein 86A 2 2
MIRT534544 RUNX1 runt related transcription factor 1 2 2
MIRT539592 SSH2 slingshot protein phosphatase 2 2 2
MIRT539676 ZBTB44 zinc finger and BTB domain containing 44 2 2
MIRT539710 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT539730 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT539755 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT539787 EMC1 ER membrane protein complex subunit 1 2 4
MIRT539812 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT539995 SLC24A4 solute carrier family 24 member 4 2 2
MIRT540073 SSH3 slingshot protein phosphatase 3 2 2
MIRT540092 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540428 FAM83F family with sequence similarity 83 member F 2 2
MIRT540512 CXCL10 C-X-C motif chemokine ligand 10 2 2
MIRT540531 ZNF417 zinc finger protein 417 2 2
MIRT540622 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT540909 PON1 paraoxonase 1 2 2
MIRT540990 ZNF460 zinc finger protein 460 2 4
MIRT541513 TOR1AIP1 torsin 1A interacting protein 1 2 2
MIRT541633 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT541665 ATP8B3 ATPase phospholipid transporting 8B3 2 2
MIRT541738 ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 2 2
MIRT541813 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT541904 VWA7 von Willebrand factor A domain containing 7 2 2
MIRT542004 XRCC2 X-ray repair cross complementing 2 2 2
MIRT542020 PEX2 peroxisomal biogenesis factor 2 2 2
MIRT542187 FUT1 fucosyltransferase 1 (H blood group) 2 6
MIRT542204 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT542337 LIMD1 LIM domains containing 1 2 2
MIRT542426 ZNF331 zinc finger protein 331 2 2
MIRT542459 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT542494 WDR13 WD repeat domain 13 2 2
MIRT542552 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542699 RPS15A ribosomal protein S15a 2 2
MIRT542819 PDE12 phosphodiesterase 12 2 2
MIRT552108 PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A 2 2
MIRT555606 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 2
MIRT564916 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 2
MIRT568609 ACVR2A activin A receptor type 2A 2 2
MIRT608702 GMPR guanosine monophosphate reductase 2 2
MIRT610061 MYBPC1 myosin binding protein C, slow type 2 2
MIRT610794 KLK2 kallikrein related peptidase 2 2 2
MIRT617179 GOSR2 golgi SNAP receptor complex member 2 2 2
MIRT620581 WBSCR27 methyltransferase like 27 2 4
MIRT623348 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623873 FUS FUS RNA binding protein 2 2
MIRT625418 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT630227 SORD sorbitol dehydrogenase 2 2
MIRT631870 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT631905 VEGFC vascular endothelial growth factor C 2 2
MIRT632005 POPDC2 popeye domain containing 2 2 2
MIRT632876 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT633313 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT633989 SLC35E2 solute carrier family 35 member E2 2 2
MIRT635248 ELOVL6 ELOVL fatty acid elongase 6 2 2
MIRT635258 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT635280 GK5 glycerol kinase 5 (putative) 2 2
MIRT635862 SLC11A2 solute carrier family 11 member 2 2 2
MIRT636624 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT637085 SELPLG selectin P ligand 2 2
MIRT639025 AAK1 AP2 associated kinase 1 2 2
MIRT640876 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT641928 SLC25A16 solute carrier family 25 member 16 2 2
MIRT642173 HEBP2 heme binding protein 2 2 2
MIRT642251 PAK4 p21 (RAC1) activated kinase 4 2 2
MIRT642854 RNF135 ring finger protein 135 2 2
MIRT643240 PRSS21 protease, serine 21 2 2
MIRT643375 TRIM16L tripartite motif containing 16 like 2 2
MIRT646931 MCCC2 methylcrotonoyl-CoA carboxylase 2 2 2
MIRT647803 FRMD8 FERM domain containing 8 2 2
MIRT650517 UFM1 ubiquitin fold modifier 1 2 2
MIRT651618 WASF3 WAS protein family member 3 2 2
MIRT655588 OTUD7B OTU deubiquitinase 7B 2 2
MIRT657652 GPR75 G protein-coupled receptor 75 2 2
MIRT657835 GJD3 gap junction protein delta 3 2 2
MIRT658357 FAM65B RHO family interacting cell polarization regulator 2 2 2
MIRT661173 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT661332 TBC1D15 TBC1 domain family member 15 2 2
MIRT662003 ZNF445 zinc finger protein 445 2 2
MIRT662194 MEI1 meiotic double-stranded break formation protein 1 2 2
MIRT663473 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT663958 ZNF554 zinc finger protein 554 2 2
MIRT665907 TBCCD1 TBCC domain containing 1 2 2
MIRT666029 STRN3 striatin 3 2 2
MIRT666496 SBNO1 strawberry notch homolog 1 2 2
MIRT667290 MYPN myopalladin 2 4
MIRT668020 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT670087 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT670598 LLGL1 LLGL1, scribble cell polarity complex component 2 4
MIRT670689 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT670848 SFT2D2 SFT2 domain containing 2 2 2
MIRT670981 MED17 mediator complex subunit 17 2 2
MIRT672621 IGF2R insulin like growth factor 2 receptor 2 2
MIRT673223 KLHDC8A kelch domain containing 8A 2 2
MIRT674265 ZNF284 zinc finger protein 284 2 2
MIRT675631 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT675806 MED28 mediator complex subunit 28 2 2
MIRT676337 PCCB propionyl-CoA carboxylase beta subunit 2 2
MIRT681724 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 2 2
MIRT682844 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT682913 FAM73A mitoguardin 1 2 2
MIRT682932 ZNF292 zinc finger protein 292 2 2
MIRT682950 RPL12 ribosomal protein L12 2 2
MIRT683030 SUSD5 sushi domain containing 5 2 2
MIRT684387 MCTS1 MCTS1, re-initiation and release factor 2 2
MIRT684687 OR7D2 olfactory receptor family 7 subfamily D member 2 2 2
MIRT687202 PLXNA3 plexin A3 2 2
MIRT689145 IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 2 2
MIRT689632 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT690598 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT690802 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT690943 GLG1 golgi glycoprotein 1 2 2
MIRT691850 OSCAR osteoclast associated, immunoglobulin-like receptor 2 2
MIRT693615 CENPL centromere protein L 2 2
MIRT693757 ZNF383 zinc finger protein 383 2 2
MIRT694014 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694594 AAR2 AAR2 splicing factor homolog 2 2
MIRT694983 PLAC8 placenta specific 8 2 2
MIRT695016 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT696414 DOCK7 dedicator of cytokinesis 7 2 2
MIRT697803 UBXN2A UBX domain protein 2A 2 2
MIRT697941 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT698775 STK4 serine/threonine kinase 4 2 2
MIRT699532 SIX4 SIX homeobox 4 2 2
MIRT701073 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT702610 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT702688 IRGQ immunity related GTPase Q 2 2
MIRT702931 HMX3 H6 family homeobox 3 2 2
MIRT703721 FAM127A retrotransposon Gag like 8C 2 2
MIRT704296 DDX19B DEAD-box helicase 19B 2 2
MIRT704332 DCTN6 dynactin subunit 6 2 2
MIRT706758 KIAA0907 KIAA0907 2 2
MIRT708483 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT710773 PHF7 PHD finger protein 7 2 2
MIRT712484 FSTL3 follistatin like 3 2 2
MIRT712784 ZNF154 zinc finger protein 154 2 2
MIRT714507 SHE Src homology 2 domain containing E 2 2
MIRT714771 TERF1 telomeric repeat binding factor 1 2 2
MIRT715263 RNF125 ring finger protein 125 2 2
MIRT716447 TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene 2 2
MIRT718198 PSMF1 proteasome inhibitor subunit 1 2 2
MIRT720001 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT720394 ZNF549 zinc finger protein 549 2 2
MIRT720597 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT721231 CRCP CGRP receptor component 2 2
MIRT721261 SH3D19 SH3 domain containing 19 2 2
MIRT721802 GRM1 glutamate metabotropic receptor 1 2 2
MIRT722573 C1orf95 stum, mechanosensory transduction mediator homolog 2 2
MIRT722842 C17orf102 chromosome 17 open reading frame 102 2 2
MIRT722909 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-5189-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-5189-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-5189-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-5189-5p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-5189-5p Osimertinib 71496458 NSC779217 approved resistant Low Non-Small Cell Lung Cancer tissue
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-5189-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-5189-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-5189-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-5189-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-5189-5p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-5189-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-5189-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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