miRTarBase - #MIRT496755


—
pre-miRNA Information
pre-miRNA hsa-mir-4763   
Genomic Coordinates chr22: 46113566 - 46113657
Description Homo sapiens miR-4763 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4763-5p
Sequence 19| CGCCUGCCCAGCCCUCCUGCU |39
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs374776264 1 dbSNP
rs1174502793 2 dbSNP
rs966122637 3 dbSNP
rs891363409 6 dbSNP
rs1303008773 8 dbSNP
rs1446379219 11 dbSNP
rs1410535134 13 dbSNP
rs1424733379 14 dbSNP
rs1372551711 16 dbSNP
rs756995936 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TGIF2   
Synonyms -
Description TGFB induced factor homeobox 2
Transcript NM_021809   
Expression
Putative miRNA Targets on TGIF2
3'UTR of TGIF2
(miRNA target sites are highlighted)		 
>TGIF2|NM_021809|3'UTR
   1 GCATCTGCCAAGAAGGGTGCTGAAGGCTCCAGCCAGCTGTCCTGGGTTTCCGTTTTGGTTCCCTTTCATACAGAGGGTTT
  81 TCTATGGATCACTGCCAAACATTGGGATCATCTCCTCTGTCCAGAGGTCTTCAACAGGAAGATGCCAGCTGGCACCACTG
 161 CACTGTGATGGGGGCCCTCTCCTCTGCTGACTCTGCCGTTTCTCCAGGCCTCCGCTCAGTGATGAGACCAAGAGATCGGA
 241 GACAAGCATGGTGCTGCTGCTTCTGCTGCTTCTCCAGAAAATCCCTGGGACACCTTTGTTCCAGCCTGGTTTCCTGGGCT
 321 GGGCTCAGGAAAGCTGCCAAATTCAGTCCTATGTTGGGTCCAAGCTGCCCCTGTGCTGTTTCTGTCAAGCCAGGTGTGGA
 401 CATTCCAAGTTCATATGCGTGAACAAAAGAAAAGAGGAACCCAGTGGATGTAACAGAACCGACTCCAGTTGAATGTTTAG
 481 ATTTTTGCTAAACTGTTTTCTTTTTCCCTTTTTTGCTGTGGTTTGCATTCACGGCAGTAGTTAGCCCAGGTGTGGGGAAC
 561 GAGAGTGCACTGCATGATAGCGTTCTGGTGAGCTGGGAAGGACCCACCACTGCCACTGAGGATTGTTTTGGAAGAAAGGA
 641 ATATTTTTATCTTGGGGACCAGCTAAGTCTCTGCAGTAGTGTGAAATTCCAAATGGTTGTTTTATCATTGGTTTGGTTTA
 721 CCAAAAAAAAGGCAGGGAAAAAAAAAAAAAACAACCGTATGAGCGCATTGGCTTGTCTGCCGCAGGCACAGAAGGGTAGA
 801 AAGCCACAGCAGGGGGCAGTCCAGCAGACTCTGACTCAACTTTCTAGGCACCTAGCAGAGAAAGATAAGATCAAAAGGTG
 881 TTTGGTTTTTCTTTTAATTTTTATTGTAGTTTTTTTGGGTGGGTGGGGGAAGTAAACTAGACTGAAGCGATGGATTTTTT
 961 TTTTCTTTTTTTTCTTTAGTGTTTTTCCCTTTGTTCTTGAACACTTTTGCCCTGCAGCCTCAGTTTTGAATTCTTTTAGC
1041 AACTTGGATTAGAGGGGCCCATATGTCAGAAGCTCCCAGCACCTCCTACTTGGGAGAAAAGTGAGCCATCTGCTGGTCAG
1121 GAAGTCCTCCAGAGAGGCAGCTTTTCCCACAATGGTGGCAGGAAACTTTGGGGAAAGCAGGAATGGTGTCCACTGCTGCG
1201 GAGGAACTGCCTTCAGAGAAGGTGGGGCTGGAAAAGGGTTAGAAGCCTCCTAGCTGGGATTGTCTTTGTTTCACCTTTCT
1281 TTAAATTAGAATTACAGAAGCCCCTGCCCAGTGAACAGATAACGATTGGTCTTATGCTCCTCCCTTTCCCCCATTTTTTC
1361 TTTTGCTGTTTTGTTTTTTGTTTTTTGTTTGTTTGTTTGTTTTTTTGAGACAGAGTCATGCTCTGTCACCCGGGCTGGAG
1441 TGCAGTGGTGCGATCTCAGCTCACTGTAACCTCCGCCTCCCGGGTTCAAGCAATTATTTGCCTCAGCCTCCCGAGTAGCT
1521 GGGATTATAGGCACCCGCCACCATGTCTGGCTTTTAGTAGAGACGGGGTTTCACCATCTTGGCCAGGCTGGTCTTGGAAC
1601 TCCTGACCTCGTGAGCCACCACGCCCAGCCTCTTTTGCTGTTTCATTGCTGACAGTGTTCAACAATATGCCCCATCTTTA
1681 TATATCCTAAGAAACACTAATCCTAGGTTATTGCTAGCCAAAATATTTTTGTCCTGAGTAGTGTCACTGGGCCAAAAGAT
1761 AGATCAGGACGACAGCCTTTAGTTTTCCTGAAATCACCAGGTCAGGCACAAGGAGAAAAGGTTCCTGGATACTGACTAAC
1841 TTGGGTGGGTCTAGCCAGGAGAAAGACAGTAACATGTGTTCTGTACTTTCTGGGAAGATCCCTGAAGCCATCACAGAGGC
1921 TCCCCAACTTCTGAGTCGCCCATCTGTTGCTGTGGGAGTGTGAACGGATCGCTGAAGGAGAGGGAGCTTTGCTCTCTCTA
2001 GGTGGGCAAGTTTCCTGGGCTCTCTGTGTTGCCTCCCTCTGGCTTCTTCCTCCCGTGCCCTCTCCCCGTGTGCCCCAGGG
2081 GGATCAGGGATCCTCACCCTCCTGAGGCCCAGTGGGGAAGAATGAACATGGCTTCATCCAGGTTAACTGATGCTGCCATT
2161 TGCCCAGCCTCTTCCATCCCAGCCCTGTCAGTGAGCCCAGGTCTGGTGCAACTGCTGCAGGATGCCTGTAGTAGGGAACT
2241 CTGGAAGTGTATTGGGCTGAGGTGGGATTTTCCCTCCCCACAGTGCACTGAGCAATGGAGGGTGGTGAGGGAGCCATGCT
2321 GCTGAATTCTGGTTGGCATTTCCCCATTATGTAAAATGGGGTGTTGGGTAGGGCAGACTCTGCTTGGGTTTGGTTGTAAG
2401 ATAAACCTGGAGGAGAAGCACAGTTGTCCCATTGAATTATTTGAGCAAAAACTACTGTAAATAACTTTTTTGTCTTTTGT
2481 CAAATAAAATTTTTTTTTGTTTTTTTAAGCAGAAACAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucguCCUCCCGACCCGUCCgc 5'
              ||:| |:||||:|||  
Target 5' aaatGGGGTGTTGGGTAGGgc 3'
 2354 - 2374 133.00 -23.20
2 
miRNA  3' ucGUCCUCCCGACCCGUCCGc 5'
            ||| |||   |||||| | 
Target 5' caCAGCAGG---GGGCAGTCc 3'
 805 - 822 128.00 -16.50
3 
miRNA  3' ucGUCCUCCCGACCCGUCCgc 5'
            ||  | ||:  ||||||  
Target 5' ccCACAATGGT--GGCAGGaa 3'
 1146 - 1164 127.00 -11.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30116712 3 COSMIC
COSN30160117 6 COSMIC
COSN30452927 51 COSMIC
COSN2382353 76 COSMIC
COSN30450305 78 COSMIC
COSN30191556 89 COSMIC
COSN30469746 115 COSMIC
COSN30156063 118 COSMIC
COSN28862549 158 COSMIC
COSN31549871 318 COSMIC
COSN29417155 491 COSMIC
COSN31570565 504 COSMIC
COSN19656205 736 COSMIC
COSN29280828 752 COSMIC
COSN30540409 1055 COSMIC
COSN31490366 1130 COSMIC
COSN28714718 1140 COSMIC
COSN31553596 1538 COSMIC
COSN31490357 1573 COSMIC
COSN31531188 1616 COSMIC
COSN26508081 1629 COSMIC
COSN31557684 1722 COSMIC
COSN31562709 1771 COSMIC
COSN20116427 1852 COSMIC
COSN9127055 2040 COSMIC
COSN5969605 2167 COSMIC
COSN31541078 2290 COSMIC
COSN26573132 2435 COSMIC
COSN31515838 2440 COSMIC
COSN31602550 2476 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs759423877 2 dbSNP
rs1466948992 3 dbSNP
rs767519437 4 dbSNP
rs1263310000 9 dbSNP
rs372115125 13 dbSNP
rs1197386499 16 dbSNP
rs764291677 17 dbSNP
rs1478638830 18 dbSNP
rs181179141 20 dbSNP
rs1479456248 22 dbSNP
rs375919073 23 dbSNP
rs757538538 24 dbSNP
rs1201158476 27 dbSNP
rs1421087646 32 dbSNP
rs1421780383 35 dbSNP
rs765494940 38 dbSNP
rs1365042920 45 dbSNP
rs750747678 46 dbSNP
rs1325594986 52 dbSNP
rs186881499 53 dbSNP
rs1194306478 72 dbSNP
rs1459315500 72 dbSNP
rs780482879 76 dbSNP
rs1308288598 85 dbSNP
rs926706674 87 dbSNP
rs747573508 88 dbSNP
rs1276073112 91 dbSNP
rs1241874042 101 dbSNP
rs1233287638 103 dbSNP
rs755621682 104 dbSNP
rs1334684932 110 dbSNP
rs777386071 111 dbSNP
rs752757544 121 dbSNP
rs1291367218 125 dbSNP
rs748873935 136 dbSNP
rs770571151 137 dbSNP
rs1448538543 141 dbSNP
rs1043893608 149 dbSNP
rs778459047 153 dbSNP
rs1335911938 163 dbSNP
rs1400753057 163 dbSNP
rs745588984 164 dbSNP
rs534464169 171 dbSNP
rs772002368 172 dbSNP
rs1384909632 173 dbSNP
rs1456580855 175 dbSNP
rs1165122347 178 dbSNP
rs768207375 181 dbSNP
rs758393108 182 dbSNP
rs1363303661 186 dbSNP
rs778016863 191 dbSNP
rs892509456 195 dbSNP
rs775551002 196 dbSNP
rs556122650 198 dbSNP
rs760760889 199 dbSNP
rs1044011954 213 dbSNP
rs903497570 214 dbSNP
rs1350190383 215 dbSNP
rs996958436 219 dbSNP
rs773890163 220 dbSNP
rs1309704331 221 dbSNP
rs1339543797 224 dbSNP
rs574266382 226 dbSNP
rs1242136801 233 dbSNP
rs1007747274 236 dbSNP
rs1285476306 238 dbSNP
rs1431100558 239 dbSNP
rs1314073291 241 dbSNP
rs1050004198 244 dbSNP
rs1017953418 254 dbSNP
rs1342053718 254 dbSNP
rs1400111001 266 dbSNP
rs1384324751 268 dbSNP
rs1156981617 272 dbSNP
rs891339985 274 dbSNP
rs1421721312 285 dbSNP
rs1008438923 291 dbSNP
rs531275777 295 dbSNP
rs1349442668 315 dbSNP
rs1387168787 329 dbSNP
rs1303052777 330 dbSNP
rs1329287983 339 dbSNP
rs1486206188 340 dbSNP
rs6065106 350 dbSNP
rs1163200934 352 dbSNP
rs1232519027 358 dbSNP
rs1471982159 359 dbSNP
rs1015692885 364 dbSNP
rs963774132 366 dbSNP
rs1188849700 367 dbSNP
rs1344463886 369 dbSNP
rs1259034863 392 dbSNP
rs747478009 397 dbSNP
rs1353839815 398 dbSNP
rs1290525796 406 dbSNP
rs997769512 415 dbSNP
rs1358193357 417 dbSNP
rs747680095 419 dbSNP
rs1429905750 420 dbSNP
rs377212348 425 dbSNP
rs572532170 425 dbSNP
rs961537873 434 dbSNP
rs951106370 435 dbSNP
rs983084545 437 dbSNP
rs909816243 446 dbSNP
rs140265869 461 dbSNP
rs549477282 462 dbSNP
rs1164252480 472 dbSNP
rs1475358478 475 dbSNP
rs1422062734 476 dbSNP
rs1196499436 482 dbSNP
rs1432951769 482 dbSNP
rs926654040 491 dbSNP
rs1267635890 494 dbSNP
rs1218905754 496 dbSNP
rs756569945 505 dbSNP
rs188876883 508 dbSNP
rs760406263 511 dbSNP
rs1337227714 512 dbSNP
rs766147696 514 dbSNP
rs1166129204 516 dbSNP
rs1369565105 517 dbSNP
rs1458046529 518 dbSNP
rs1294911243 519 dbSNP
rs1388395902 521 dbSNP
rs1056597047 522 dbSNP
rs1341207965 528 dbSNP
rs1298306811 531 dbSNP
rs564854267 533 dbSNP
rs776629101 534 dbSNP
rs1367205104 538 dbSNP
rs1409704116 543 dbSNP
rs1035696472 545 dbSNP
rs960588468 551 dbSNP
rs1296880196 552 dbSNP
rs6101370 553 dbSNP
rs1247327711 558 dbSNP
rs544788415 561 dbSNP
rs560061704 562 dbSNP
rs1188988590 567 dbSNP
rs571731365 570 dbSNP
rs182005523 574 dbSNP
rs1203389195 575 dbSNP
rs945213475 577 dbSNP
rs1250476948 578 dbSNP
rs1456227240 581 dbSNP
rs560882496 582 dbSNP
rs1199181096 583 dbSNP
rs902061047 585 dbSNP
rs867735112 588 dbSNP
rs1463882785 597 dbSNP
rs1217511210 603 dbSNP
rs1186139732 607 dbSNP
rs1275605622 610 dbSNP
rs1389082419 612 dbSNP
rs925060357 617 dbSNP
rs1423887216 630 dbSNP
rs997875782 631 dbSNP
rs1029387768 646 dbSNP
rs6101371 652 dbSNP
rs1405941090 668 dbSNP
rs1174598907 693 dbSNP
rs75484069 696 dbSNP
rs1425266123 699 dbSNP
rs1017228845 700 dbSNP
rs1437500161 706 dbSNP
rs1239751861 709 dbSNP
rs186240598 711 dbSNP
rs1390748317 717 dbSNP
rs1432733492 722 dbSNP
rs1212174114 723 dbSNP
rs1254125037 723 dbSNP
rs1460732394 723 dbSNP
rs1313960598 731 dbSNP
rs1319790060 731 dbSNP
rs200293257 735 dbSNP
rs1239662007 738 dbSNP
rs1248235652 738 dbSNP
rs1447916183 738 dbSNP
rs556291931 738 dbSNP
rs60964912 738 dbSNP
rs755821096 738 dbSNP
rs764215917 739 dbSNP
rs980723841 742 dbSNP
rs1033504856 749 dbSNP
rs960559402 750 dbSNP
rs1157795453 751 dbSNP
rs1417449979 752 dbSNP
rs1229401005 753 dbSNP
rs890812086 757 dbSNP
rs944266180 758 dbSNP
rs1253829670 759 dbSNP
rs1208725432 764 dbSNP
rs1238528806 766 dbSNP
rs1037274799 768 dbSNP
rs1483321490 768 dbSNP
rs897311359 769 dbSNP
rs995665610 775 dbSNP
rs533429497 777 dbSNP
rs74748470 782 dbSNP
rs905903180 783 dbSNP
rs925490222 784 dbSNP
rs1001643983 788 dbSNP
rs1321492721 797 dbSNP
rs1159654614 804 dbSNP
rs1039288558 811 dbSNP
rs901998916 814 dbSNP
rs1036070144 816 dbSNP
rs960056196 822 dbSNP
rs1455443004 829 dbSNP
rs933507539 832 dbSNP
rs1051256028 838 dbSNP
rs1397537960 846 dbSNP
rs992056772 852 dbSNP
rs1298363260 855 dbSNP
rs1020920179 868 dbSNP
rs1301097015 871 dbSNP
rs966528845 884 dbSNP
rs979643553 886 dbSNP
rs925145052 888 dbSNP
rs540350914 910 dbSNP
rs932370808 919 dbSNP
rs4812359 921 dbSNP
rs1004246270 931 dbSNP
rs1191434394 937 dbSNP
rs1487310196 939 dbSNP
rs985241745 944 dbSNP
rs548061480 949 dbSNP
rs566834781 950 dbSNP
rs113760296 955 dbSNP
rs1264016249 955 dbSNP
rs898189322 955 dbSNP
rs75858122 956 dbSNP
rs1002108294 964 dbSNP
rs1033619667 966 dbSNP
rs1278064329 966 dbSNP
rs1322723513 966 dbSNP
rs960505976 966 dbSNP
rs1278328517 969 dbSNP
rs943730712 974 dbSNP
rs992007666 974 dbSNP
rs1349060083 975 dbSNP
rs1294945268 978 dbSNP
rs1228139438 979 dbSNP
rs6101373 980 dbSNP
rs1314410556 982 dbSNP
rs1168439809 986 dbSNP
rs1478794887 987 dbSNP
rs932092798 989 dbSNP
rs1253689571 1004 dbSNP
rs1037243524 1005 dbSNP
rs1265474863 1010 dbSNP
rs897378029 1018 dbSNP
rs1211876151 1019 dbSNP
rs1488974421 1021 dbSNP
rs1257900050 1022 dbSNP
rs1182539103 1024 dbSNP
rs931585376 1029 dbSNP
rs1049015531 1034 dbSNP
rs549686628 1037 dbSNP
rs1320667816 1044 dbSNP
rs1259300238 1053 dbSNP
rs906044119 1055 dbSNP
rs1002011148 1056 dbSNP
rs1302867874 1061 dbSNP
rs1471516361 1062 dbSNP
rs376493075 1064 dbSNP
rs964703069 1073 dbSNP
rs1467093225 1077 dbSNP
rs150382819 1081 dbSNP
rs1425825397 1083 dbSNP
rs895815211 1089 dbSNP
rs923535715 1090 dbSNP
rs138103023 1095 dbSNP
rs1201280227 1097 dbSNP
rs1434045410 1105 dbSNP
rs1173852415 1106 dbSNP
rs1020308019 1108 dbSNP
rs933455012 1108 dbSNP
rs1239257169 1109 dbSNP
rs1200387617 1118 dbSNP
rs966580114 1119 dbSNP
rs71351028 1128 dbSNP
rs1000809647 1134 dbSNP
rs1032563291 1151 dbSNP
rs1352580195 1153 dbSNP
rs556678847 1160 dbSNP
rs898146309 1167 dbSNP
rs1377384320 1169 dbSNP
rs767778892 1173 dbSNP
rs1394290760 1187 dbSNP
rs1400147070 1199 dbSNP
rs537986567 1201 dbSNP
rs912351734 1210 dbSNP
rs1001888824 1213 dbSNP
rs965106902 1223 dbSNP
rs1233885105 1225 dbSNP
rs1187442914 1227 dbSNP
rs1218044319 1235 dbSNP
rs1441239769 1237 dbSNP
rs538700167 1238 dbSNP
rs1200490300 1239 dbSNP
rs553614883 1249 dbSNP
rs571692015 1261 dbSNP
rs1283371004 1263 dbSNP
rs542256684 1265 dbSNP
rs918270106 1270 dbSNP
rs1346578923 1275 dbSNP
rs1354146356 1292 dbSNP
rs1283444276 1300 dbSNP
rs1242495491 1301 dbSNP
rs931527008 1302 dbSNP
rs1251259534 1304 dbSNP
rs1048667919 1307 dbSNP
rs1415410628 1312 dbSNP
rs1276363854 1314 dbSNP
rs927433955 1322 dbSNP
rs937561792 1323 dbSNP
rs6016004 1325 dbSNP
rs575891459 1332 dbSNP
rs1163081812 1338 dbSNP
rs543366234 1343 dbSNP
rs1247126777 1348 dbSNP
rs895872029 1352 dbSNP
rs536820842 1353 dbSNP
rs1189440983 1354 dbSNP
rs1260499898 1354 dbSNP
rs1477172571 1354 dbSNP
rs1488442876 1362 dbSNP
rs1032856010 1364 dbSNP
rs1450190230 1367 dbSNP
rs548772022 1369 dbSNP
rs964652584 1372 dbSNP
rs1218006666 1378 dbSNP
rs974721432 1380 dbSNP
rs1276438688 1381 dbSNP
rs1402045808 1381 dbSNP
rs923484961 1381 dbSNP
rs1323166506 1382 dbSNP
rs190701127 1384 dbSNP
rs544238390 1384 dbSNP
rs908022912 1384 dbSNP
rs954955544 1384 dbSNP
rs1195266991 1395 dbSNP
rs1010329913 1396 dbSNP
rs1041718799 1399 dbSNP
rs1196307428 1400 dbSNP
rs1368949094 1400 dbSNP
rs570280329 1404 dbSNP
rs1316031647 1405 dbSNP
rs537501558 1405 dbSNP
rs1259951727 1408 dbSNP
rs1352052125 1421 dbSNP
rs1362766355 1424 dbSNP
rs1274419208 1429 dbSNP
rs1032284705 1432 dbSNP
rs1293511886 1433 dbSNP
rs1366498188 1436 dbSNP
rs772312060 1448 dbSNP
rs558784653 1452 dbSNP
rs1006712743 1453 dbSNP
rs937626967 1459 dbSNP
rs1166549742 1461 dbSNP
rs1173467243 1464 dbSNP
rs1019408772 1466 dbSNP
rs896194395 1471 dbSNP
rs965075167 1475 dbSNP
rs773695341 1476 dbSNP
rs1253360847 1477 dbSNP
rs972468787 1482 dbSNP
rs570820407 1483 dbSNP
rs952434308 1488 dbSNP
rs1308136615 1491 dbSNP
rs1278085514 1493 dbSNP
rs984775121 1504 dbSNP
rs1217654993 1507 dbSNP
rs1347457717 1508 dbSNP
rs1437637489 1513 dbSNP
rs1304467290 1514 dbSNP
rs1446449718 1516 dbSNP
rs1375169834 1519 dbSNP
rs1252327354 1522 dbSNP
rs1333942007 1531 dbSNP
rs909238030 1534 dbSNP
rs1443649237 1537 dbSNP
rs1465237651 1538 dbSNP
rs749770871 1539 dbSNP
rs1173405733 1543 dbSNP
rs1415706124 1545 dbSNP
rs927599928 1552 dbSNP
rs1395270146 1558 dbSNP
rs1388465354 1561 dbSNP
rs937595043 1565 dbSNP
rs143715787 1566 dbSNP
rs917442464 1567 dbSNP
rs1416202812 1574 dbSNP
rs145811351 1583 dbSNP
rs1236951327 1586 dbSNP
rs1032353882 1589 dbSNP
rs779427424 1595 dbSNP
rs1041855111 1598 dbSNP
rs996254645 1599 dbSNP
rs1390024978 1601 dbSNP
rs549354407 1603 dbSNP
rs1140732 1604 dbSNP
rs904504829 1610 dbSNP
rs936056145 1611 dbSNP
rs954738262 1612 dbSNP
rs1054104704 1623 dbSNP
rs1309658809 1626 dbSNP
rs889671140 1629 dbSNP
rs1006779726 1630 dbSNP
rs1301639763 1636 dbSNP
rs1324212241 1647 dbSNP
rs1429383447 1655 dbSNP
rs567676128 1663 dbSNP
rs182600714 1664 dbSNP
rs367638483 1672 dbSNP
rs1015610561 1699 dbSNP
rs1297185130 1708 dbSNP
rs1417549772 1716 dbSNP
rs1362182824 1718 dbSNP
rs1357972499 1720 dbSNP
rs550231100 1731 dbSNP
rs1159622394 1734 dbSNP
rs138657186 1734 dbSNP
rs1183525787 1736 dbSNP
rs538896959 1740 dbSNP
rs1216127851 1743 dbSNP
rs993858143 1755 dbSNP
rs746348386 1771 dbSNP
rs1329592310 1772 dbSNP
rs1210591303 1782 dbSNP
rs1216905212 1787 dbSNP
rs1246086341 1789 dbSNP
rs1321502447 1791 dbSNP
rs1311132531 1798 dbSNP
rs1235737381 1799 dbSNP
rs1298383707 1801 dbSNP
rs1355533934 1812 dbSNP
rs1277061252 1814 dbSNP
rs1386613541 1816 dbSNP
rs41276988 1816 dbSNP
rs919637669 1818 dbSNP
rs565485783 1819 dbSNP
rs535950467 1821 dbSNP
rs371836516 1822 dbSNP
rs990605065 1823 dbSNP
rs1166831219 1833 dbSNP
rs917578387 1841 dbSNP
rs112208120 1850 dbSNP
rs60435168 1850 dbSNP
rs778161295 1850 dbSNP
rs151113715 1852 dbSNP
rs200316735 1853 dbSNP
rs80020539 1854 dbSNP
rs201285664 1855 dbSNP
rs1476901318 1859 dbSNP
rs1042276641 1864 dbSNP
rs993094316 1866 dbSNP
rs1413245709 1868 dbSNP
rs917411112 1869 dbSNP
rs775963186 1873 dbSNP
rs201834011 1878 dbSNP
rs902435178 1883 dbSNP
rs946221280 1891 dbSNP
rs1264123638 1895 dbSNP
rs1216062286 1901 dbSNP
rs1157648670 1911 dbSNP
rs977502520 1920 dbSNP
rs1384809824 1922 dbSNP
rs1399644710 1926 dbSNP
rs1327682675 1933 dbSNP
rs936476418 1936 dbSNP
rs770730836 1942 dbSNP
rs1365190884 1943 dbSNP
rs1441398723 1947 dbSNP
rs926093465 1950 dbSNP
rs185940389 1951 dbSNP
rs1053547208 1961 dbSNP
rs554110313 1963 dbSNP
rs1050425029 1964 dbSNP
rs889129192 1969 dbSNP
rs142756264 1970 dbSNP
rs572275178 1971 dbSNP
rs1030396278 1975 dbSNP
rs1432860448 1976 dbSNP
rs901009051 1979 dbSNP
rs993994020 1987 dbSNP
rs1195833083 1991 dbSNP
rs1025904236 1992 dbSNP
rs1238029379 1996 dbSNP
rs1197313519 2003 dbSNP
rs759122025 2012 dbSNP
rs1005305722 2018 dbSNP
rs1015143781 2021 dbSNP
rs1232053895 2026 dbSNP
rs963968980 2029 dbSNP
rs1266189452 2039 dbSNP
rs1305221859 2042 dbSNP
rs1349822266 2055 dbSNP
rs1201113175 2059 dbSNP
rs868422287 2060 dbSNP
rs41276990 2064 dbSNP
rs1440767022 2066 dbSNP
rs1393135588 2067 dbSNP
rs1398687589 2068 dbSNP
rs1298866795 2071 dbSNP
rs866118826 2072 dbSNP
rs765223024 2073 dbSNP
rs1454932125 2078 dbSNP
rs1380133226 2079 dbSNP
rs1177284405 2081 dbSNP
rs1473788293 2083 dbSNP
rs958891289 2085 dbSNP
rs1251901130 2087 dbSNP
rs1199354145 2093 dbSNP
rs990552805 2097 dbSNP
rs775264706 2102 dbSNP
rs1234645867 2109 dbSNP
rs558609562 2112 dbSNP
rs1352709999 2114 dbSNP
rs993063105 2115 dbSNP
rs1363731187 2117 dbSNP
rs1306859284 2120 dbSNP
rs576957273 2128 dbSNP
rs1241069108 2136 dbSNP
rs1024603435 2142 dbSNP
rs1311960473 2149 dbSNP
rs775569502 2154 dbSNP
rs1373719009 2155 dbSNP
rs1314986536 2156 dbSNP
rs923668723 2162 dbSNP
rs1360270712 2173 dbSNP
rs113228049 2174 dbSNP
rs1471380964 2176 dbSNP
rs559594378 2181 dbSNP
rs1364814259 2185 dbSNP
rs1403812453 2190 dbSNP
rs1432297704 2192 dbSNP
rs926132320 2206 dbSNP
rs527747479 2207 dbSNP
rs1052112 2208 dbSNP
rs1259088183 2211 dbSNP
rs1211117158 2213 dbSNP
rs936071030 2220 dbSNP
rs986647296 2226 dbSNP
rs554304872 2230 dbSNP
rs944747320 2231 dbSNP
rs1411464608 2233 dbSNP
rs1351134544 2235 dbSNP
rs767762558 2238 dbSNP
rs1304517217 2239 dbSNP
rs922487502 2241 dbSNP
rs1242585050 2243 dbSNP
rs1353633741 2246 dbSNP
rs890544075 2249 dbSNP
rs1415504278 2256 dbSNP
rs1340076841 2263 dbSNP
rs1322027028 2267 dbSNP
rs543161450 2271 dbSNP
rs1316507359 2272 dbSNP
rs1335112003 2272 dbSNP
rs1402745612 2277 dbSNP
rs1233954336 2279 dbSNP
rs1386207601 2284 dbSNP
rs1004847823 2286 dbSNP
rs1276510953 2288 dbSNP
rs1419360939 2291 dbSNP
rs1015338661 2292 dbSNP
rs899200718 2302 dbSNP
rs1239933380 2307 dbSNP
rs750669100 2312 dbSNP
rs1447348181 2319 dbSNP
rs1046872383 2320 dbSNP
rs1034627259 2335 dbSNP
rs1210187716 2343 dbSNP
rs752172327 2351 dbSNP
rs888292540 2352 dbSNP
rs1005290233 2356 dbSNP
rs1233907723 2357 dbSNP
rs1014437392 2364 dbSNP
rs573471801 2366 dbSNP
rs970879755 2368 dbSNP
rs1250321052 2372 dbSNP
rs977901747 2374 dbSNP
rs894144907 2375 dbSNP
rs1439188245 2377 dbSNP
rs1013964327 2387 dbSNP
rs1434112557 2393 dbSNP
rs1166289493 2401 dbSNP
rs1464595356 2401 dbSNP
rs923588388 2418 dbSNP
rs1201702320 2420 dbSNP
rs957723778 2420 dbSNP
rs1245797867 2424 dbSNP
rs989333813 2436 dbSNP
rs561240625 2460 dbSNP
rs201975059 2469 dbSNP
rs1253489825 2470 dbSNP
rs199875415 2472 dbSNP
rs796552455 2472 dbSNP
rs1437312897 2474 dbSNP
rs1023985488 2475 dbSNP
rs1172433090 2475 dbSNP
rs1216524808 2482 dbSNP
rs1390411232 2483 dbSNP
rs746266570 2486 dbSNP
rs183220779 2494 dbSNP
rs931782692 2494 dbSNP
rs1327146287 2495 dbSNP
rs756330904 2496 dbSNP
rs911769611 2498 dbSNP
rs940765743 2499 dbSNP
rs1395557491 2502 dbSNP
rs187660553 2503 dbSNP
rs1171381252 2504 dbSNP
rs1423952335 2504 dbSNP
rs1455411750 2508 dbSNP
rs1325469437 2517 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC
Disease MIMAT0019912
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020023. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_021809 | 3UTR | UGAGCGCAUUGGCUUGUCUGCCGCAGGCACAGAAGGGUAGAAAGCCACAGCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1020023
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000373874.2 | 3UTR | UUGGCUUGUCUGCCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
69 hsa-miR-4763-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT116035 DEPDC1 DEP domain containing 1 2 2
MIRT347197 SIN3B SIN3 transcription regulator family member B 2 2
MIRT443248 C9orf170 chromosome 9 open reading frame 170 2 2
MIRT475164 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT495486 VTI1B vesicle transport through interaction with t-SNAREs 1B 2 2
MIRT496755 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT496863 C21orf2 chromosome 21 open reading frame 2 2 2
MIRT499264 NBPF11 NBPF member 11 2 2
MIRT499517 MAFK MAF bZIP transcription factor K 2 2
MIRT512952 MKI67 marker of proliferation Ki-67 2 2
MIRT514656 NUP93 nucleoporin 93 2 2
MIRT517986 SLC16A13 solute carrier family 16 member 13 2 2
MIRT522816 KLHL9 kelch like family member 9 2 4
MIRT525495 CD63 CD63 molecule 2 2
MIRT528111 FOXH1 forkhead box H1 2 2
MIRT531683 MYO3A myosin IIIA 2 2
MIRT534806 RAB37 RAB37, member RAS oncogene family 2 2
MIRT573041 SHMT1 serine hydroxymethyltransferase 1 2 2
MIRT576720 Wars tryptophanyl-tRNA synthetase 2 2
MIRT609727 MLXIPL MLX interacting protein like 2 2
MIRT610843 FAM180B family with sequence similarity 180 member B 2 4
MIRT614735 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT616981 EPOR erythropoietin receptor 2 2
MIRT617265 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT619405 INTS7 integrator complex subunit 7 2 2
MIRT621832 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT621893 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT630263 SMIM14 small integral membrane protein 14 2 2
MIRT634879 SENP8 SUMO/sentrin peptidase family member, NEDD8 specific 2 2
MIRT636863 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT637653 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT637699 ZNF439 zinc finger protein 439 2 2
MIRT637759 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT638193 TAOK1 TAO kinase 1 2 2
MIRT638996 ADO 2-aminoethanethiol dioxygenase 2 2
MIRT642221 RABAC1 Rab acceptor 1 2 2
MIRT643327 ATCAY ATCAY, caytaxin 2 4
MIRT643419 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT644499 RNF14 ring finger protein 14 2 2
MIRT644603 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT644795 C21orf59 chromosome 21 open reading frame 59 2 2
MIRT648732 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT653856 SHE Src homology 2 domain containing E 2 2
MIRT654129 RPL14 ribosomal protein L14 2 4
MIRT658876 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT671624 C20orf144 chromosome 20 open reading frame 144 2 4
MIRT677367 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT677579 TRIM65 tripartite motif containing 65 2 2
MIRT678220 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT679613 RRP36 ribosomal RNA processing 36 2 2
MIRT686081 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT691817 ICA1L islet cell autoantigen 1 like 2 2
MIRT693869 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT694544 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694926 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2 2
MIRT697758 USP37 ubiquitin specific peptidase 37 2 2
MIRT697891 UBE2B ubiquitin conjugating enzyme E2 B 2 2
MIRT701569 MYPN myopalladin 2 2
MIRT703081 GPRIN3 GPRIN family member 3 2 2
MIRT708104 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT708320 NT5C 5', 3'-nucleotidase, cytosolic 2 2
MIRT709878 TRAF1 TNF receptor associated factor 1 2 2
MIRT713545 GJB1 gap junction protein beta 1 2 2
MIRT716275 NUP85 nucleoporin 85 2 2
MIRT716621 CRCP CGRP receptor component 2 2
MIRT717987 C9orf171 cilia and flagella associated protein 77 2 2
MIRT718438 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722544 AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2 2
MIRT724013 F2RL1 F2R like trypsin receptor 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4763 Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Doxorubicin 31703 NSC123127 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Vincristine 5978 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-mir-4763 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4763 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4763-5p Anthracycline 30323 NSC82151 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Fluorouracil 3385 NSC19893 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Cyclophosphamide 2907 NSC26271 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Methotrexate 126941 NSC740 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Taxol 36314 NSC125973 approved resistant High Breast Cancer tissue
hsa-miR-4763-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-4763-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4763-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-4763-5p Platinum 23939 sensitive tissue (non-small cell lung cancer)
hsa-miR-4763-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4763-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-4763-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

Error report submission