miRTarBase - #MIRT496762


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pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-5p
Sequence 16| UAAAUCCCAUGGUGCCUUCUCCU |38
Evidence Experimental
Experiments SAGE
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 10 + 51299590 29233923, 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs113212828 2 dbSNP
rs1265154909 7 dbSNP
rs76759855 9 dbSNP
rs1032735304 10 dbSNP
rs1318073696 10 dbSNP
rs1486056689 11 dbSNP
rs1225930966 12 dbSNP
rs1011066926 14 dbSNP
rs1261327694 19 dbSNP
rs1020985018 22 dbSNP
rs1426923077 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MANBAL   
Synonyms -
Description mannosidase beta like
Transcript NM_001003897   
Other Transcripts NM_022077   
Expression
Putative miRNA Targets on MANBAL
3'UTR of MANBAL
(miRNA target sites are highlighted)		 
>MANBAL|NM_001003897|3'UTR
   1 AAGAGGAGGCCTGAGGAGCTGGGCGGGCAGGGAGAGGGTCTTGGGGACAGCCCTCCTGGGAATCTACATTGTGTTCCCCC
  81 GCATTCCAGGCTCAGGGTCTGAGGAGGCTGTGACGCCCTATGACCGCAGAGATCTAGACAGTCGTAACAGTCCCCAGGCT
 161 CCAGCTGGGCAATCCACCACTTCCTCTTCCTTCTGCTTCTGTGACGGTTTAGAGTCAAGGGGGCTGAAACACACTGTGAG
 241 CATAGACTGTATTAGGTTTGTTCAGAAGCCGGGTCAGCTCACAGAGTCACATTTTCTTGCTTAGTCATGTGTCCCTCCTT
 321 GAGTTGCCCCCTCCTTGTGGGTTTACACTACATTTGGGAGTCATTGTCTAATGCTGACAAGCACACCCTCTCCCATTATT
 401 TGTGCACTACAGATCTCCTCCTGATCAGTCACCTTTGTTGCTGCTGTGTAGACAGAGCCAGGCCTCACCTGTTTGTTTAG
 481 GCCAAGATGCCATGGACATGCAGCGTTAGTGATCCCACTAGCTGTGACAGCCAGGCCCAGAAAATGCCTGGCGTGAGAGC
 561 CAGCAGACAGCCAGGCCAGGGTAGGCAGTGCCTGCTTCTGCTCCATCAGGTGCAGGGGATTTGGCTGAAGGCGTGCATAT
 641 TTCCTGGGCACAAACTTCCTGAGCCTCTGAAATGGGAGGCTCGTCAATTTCAGACCAACCTCTTTTCAACCCATCATAGC
 721 ACGTTCAAGGTGTGCCTTTTACTTCTACCTGTACATCCCCCATCCCTTCAATTCTTTCATTCCCTGACCAGTGAGAGGGT
 801 TCCTGGGGGAAGTATGGTGAATAAACTGACATGCATGCTTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
 881 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uccucuUCCGUGGUACCCUAAAu 5'
                |||:: || ||||||| 
Target 5' tccatcAGGTG-CAGGGGATTTg 3'
 602 - 623 156.00 -14.90
2 
miRNA  3' ucCUCU-UCCGUGGUACCCUAAau 5'
            |:|| || | :| ||||| |  
Target 5' tgGGGACAGCCCTCCTGGGAATct 3'
 42 - 65 113.00 -14.86
3 
miRNA  3' ucCUCUUCCGUGG-UACCCUaaau 5'
            ||||:||: || : ||||    
Target 5' gtGAGAGGGTTCCTGGGGGAagta 3'
 791 - 814 109.00 -20.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN191888 4 COSMIC
COSN4893120 6 COSMIC
COSN20072863 8 COSMIC
COSN31502782 27 COSMIC
COSN30178145 35 COSMIC
COSN30481342 56 COSMIC
COSN509309 56 COSMIC
COSN30154653 65 COSMIC
COSN13859830 81 COSMIC
COSN30113451 82 COSMIC
COSN31577812 125 COSMIC
COSN30167391 230 COSMIC
COSN5133931 246 COSMIC
COSN21788180 280 COSMIC
COSN31576250 683 COSMIC
COSN16486756 811 COSMIC
COSN30174049 820 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1172585041 6 dbSNP
rs769002006 9 dbSNP
rs550915323 10 dbSNP
rs371345376 11 dbSNP
rs756725791 12 dbSNP
rs371292558 13 dbSNP
rs1025985586 14 dbSNP
rs1359946921 16 dbSNP
rs1380966713 19 dbSNP
rs745395141 20 dbSNP
rs11905967 21 dbSNP
rs1391406911 24 dbSNP
rs746745446 25 dbSNP
rs1301503015 26 dbSNP
rs201414663 30 dbSNP
rs1416781551 37 dbSNP
rs1211683768 40 dbSNP
rs781093781 42 dbSNP
rs1485511213 44 dbSNP
rs959185867 45 dbSNP
rs747893972 47 dbSNP
rs1263622202 49 dbSNP
rs1425109609 57 dbSNP
rs551454296 69 dbSNP
rs1486168613 72 dbSNP
rs1316375704 77 dbSNP
rs1249774826 79 dbSNP
rs533899540 81 dbSNP
rs762319695 82 dbSNP
rs1274111053 92 dbSNP
rs1247262488 98 dbSNP
rs1484187553 107 dbSNP
rs1180114850 111 dbSNP
rs1004102166 114 dbSNP
rs879069470 115 dbSNP
rs553784756 116 dbSNP
rs1395667934 117 dbSNP
rs898121284 119 dbSNP
rs11537904 120 dbSNP
rs1370939273 121 dbSNP
rs535205450 123 dbSNP
rs374426628 126 dbSNP
rs749172031 127 dbSNP
rs1013781628 135 dbSNP
rs1467923740 137 dbSNP
rs1176166801 142 dbSNP
rs914856980 144 dbSNP
rs574717341 145 dbSNP
rs535717833 154 dbSNP
rs901553585 162 dbSNP
rs1446452174 171 dbSNP
rs557242552 173 dbSNP
rs1344392080 176 dbSNP
rs575550313 178 dbSNP
rs1047972268 180 dbSNP
rs886088582 185 dbSNP
rs1234210213 186 dbSNP
rs1372292881 190 dbSNP
rs1351437252 198 dbSNP
rs1412104414 200 dbSNP
rs545921440 206 dbSNP
rs1372890011 207 dbSNP
rs1220092653 211 dbSNP
rs564593305 220 dbSNP
rs766186897 221 dbSNP
rs895084271 229 dbSNP
rs753530843 230 dbSNP
rs778958045 230 dbSNP
rs1171133442 240 dbSNP
rs1391483890 240 dbSNP
rs925316927 254 dbSNP
rs1208609826 255 dbSNP
rs182290077 258 dbSNP
rs1200784962 261 dbSNP
rs1024817822 271 dbSNP
rs971002404 272 dbSNP
rs981548689 273 dbSNP
rs974829258 274 dbSNP
rs1278303318 280 dbSNP
rs1210193946 285 dbSNP
rs1043404 287 dbSNP
rs561837207 292 dbSNP
rs1237405461 296 dbSNP
rs1335537563 297 dbSNP
rs1308066914 299 dbSNP
rs11907459 300 dbSNP
rs1371969029 308 dbSNP
rs990163435 311 dbSNP
rs1051381332 314 dbSNP
rs1249086247 317 dbSNP
rs1469293749 318 dbSNP
rs1468224424 319 dbSNP
rs1362855863 326 dbSNP
rs1182522578 327 dbSNP
rs1473762746 329 dbSNP
rs550851936 331 dbSNP
rs562642258 332 dbSNP
rs117968342 336 dbSNP
rs943640970 341 dbSNP
rs1443517202 344 dbSNP
rs1412284391 347 dbSNP
rs551124666 352 dbSNP
rs939934864 356 dbSNP
rs1806940 357 dbSNP
rs1268984318 359 dbSNP
rs533614936 364 dbSNP
rs1352057195 369 dbSNP
rs933508173 371 dbSNP
rs1291235116 375 dbSNP
rs1414028986 376 dbSNP
rs1001856122 386 dbSNP
rs1336165902 395 dbSNP
rs1047460348 396 dbSNP
rs886201572 403 dbSNP
rs542071162 405 dbSNP
rs1365514895 410 dbSNP
rs1037333576 414 dbSNP
rs755134963 415 dbSNP
rs1043415 421 dbSNP
rs1164669233 425 dbSNP
rs777540294 426 dbSNP
rs1473371044 428 dbSNP
rs1239714052 434 dbSNP
rs535658860 441 dbSNP
rs966903514 444 dbSNP
rs1446471894 446 dbSNP
rs1248760167 447 dbSNP
rs557633638 450 dbSNP
rs1001561107 455 dbSNP
rs1207278777 463 dbSNP
rs1227526632 470 dbSNP
rs1270616215 473 dbSNP
rs1032583984 479 dbSNP
rs1428596972 488 dbSNP
rs1363773696 494 dbSNP
rs1320663833 498 dbSNP
rs1012158146 499 dbSNP
rs1025351223 500 dbSNP
rs1391838794 502 dbSNP
rs906350505 505 dbSNP
rs1221815901 506 dbSNP
rs964706448 516 dbSNP
rs1043432 526 dbSNP
rs1451962468 527 dbSNP
rs923244300 533 dbSNP
rs1031733409 550 dbSNP
rs539803557 551 dbSNP
rs1467249664 553 dbSNP
rs990114641 554 dbSNP
rs1222648101 565 dbSNP
rs1451934421 568 dbSNP
rs1021625746 572 dbSNP
rs1390317116 575 dbSNP
rs983514172 576 dbSNP
rs965110503 578 dbSNP
rs1043453 579 dbSNP
rs144953597 580 dbSNP
rs1298329152 587 dbSNP
rs149057243 589 dbSNP
rs1368214797 591 dbSNP
rs919821923 592 dbSNP
rs540696053 593 dbSNP
rs1325727990 594 dbSNP
rs780319564 595 dbSNP
rs1348359874 596 dbSNP
rs1440185558 598 dbSNP
rs1371709452 599 dbSNP
rs3171266 599 dbSNP
rs1171101893 604 dbSNP
rs749444177 606 dbSNP
rs1394594742 607 dbSNP
rs1367524108 610 dbSNP
rs1230480260 615 dbSNP
rs1268393752 619 dbSNP
rs1338462274 621 dbSNP
rs1479140092 623 dbSNP
rs1248176766 624 dbSNP
rs907590577 634 dbSNP
rs142430218 635 dbSNP
rs368233036 638 dbSNP
rs896115662 643 dbSNP
rs1466848453 648 dbSNP
rs1345071245 649 dbSNP
rs1219389876 658 dbSNP
rs949156917 658 dbSNP
rs1369292324 664 dbSNP
rs544460630 666 dbSNP
rs1042133329 674 dbSNP
rs1351539390 675 dbSNP
rs151295793 677 dbSNP
rs766827764 683 dbSNP
rs1046300997 684 dbSNP
rs1191606227 697 dbSNP
rs1032898611 701 dbSNP
rs533104913 703 dbSNP
rs1406049957 706 dbSNP
rs1176893117 716 dbSNP
rs999344157 717 dbSNP
rs1252315246 723 dbSNP
rs1052274687 724 dbSNP
rs545310967 733 dbSNP
rs1165373167 734 dbSNP
rs372480505 743 dbSNP
rs1011663154 748 dbSNP
rs1021739018 752 dbSNP
rs1313500394 754 dbSNP
rs1461114961 756 dbSNP
rs954707036 759 dbSNP
rs964728372 765 dbSNP
rs996593830 766 dbSNP
rs1290619657 767 dbSNP
rs1413409131 772 dbSNP
rs1043494 775 dbSNP
rs1303997491 783 dbSNP
rs1450275373 788 dbSNP
rs1343556642 793 dbSNP
rs1043507 796 dbSNP
rs140644906 803 dbSNP
rs1457988947 804 dbSNP
rs1412362946 814 dbSNP
rs1161110550 818 dbSNP
rs1014995047 826 dbSNP
rs1255369894 829 dbSNP
rs373425540 836 dbSNP
rs961526599 840 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC
Disease MIMAT0003273
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020023. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uccucuuCCGUGGUACCCUAaau 5'
                 ||| : | || :|   
Target 5' -----uuGGC-UGAAGGCGUgca 3'
 		1 - 17
Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020023
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000373606.3 | 3UTR | UUGGCUGAAGGCGUGCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LUAD 0.968 0 0.933 0 9 Click to see details
LIHC -0.689 0 -0.659 0 20 Click to see details
BRCA -0.41 0 -0.310 0.02 46 Click to see details
HNSC -0.385 0.07 -0.035 0.45 16 Click to see details
CHOL -0.966 0.08 -1.000 0.5 3 Click to see details
UCEC 0.443 0.12 0.400 0.14 9 Click to see details
KICH 0.296 0.14 0.164 0.28 15 Click to see details
BLCA -0.302 0.18 -0.327 0.16 11 Click to see details
PAAD 0.831 0.19 0.500 0.33 3 Click to see details
LUSC -0.185 0.2 -0.158 0.24 23 Click to see details
PRAD 0.29 0.24 0.214 0.31 8 Click to see details
STAD 0.15 0.28 0.236 0.17 18 Click to see details
KIRC 0.084 0.34 0.061 0.38 27 Click to see details
KIRP 0.095 0.36 0.049 0.43 17 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
THCA -0.019 0.45 0.008 0.48 48 Click to see details
107 hsa-miR-605-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT001230 SEC24D SEC24 homolog D, COPII coat complex component 3 1
MIRT016155 TP53 tumor protein p53 2 1
MIRT016156 TCEAL1 transcription elongation factor A like 1 1 1
MIRT016157 MDM2 MDM2 proto-oncogene 2 1
MIRT040476 YBX1 Y-box binding protein 1 1 1
MIRT040477 TMEM64 transmembrane protein 64 1 1
MIRT040478 KDM5C lysine demethylase 5C 1 1
MIRT040479 TRAF4 TNF receptor associated factor 4 1 1
MIRT040480 DRG1 developmentally regulated GTP binding protein 1 1 1
MIRT040481 BCL9 B-cell CLL/lymphoma 9 1 1
MIRT055125 SCD stearoyl-CoA desaturase 2 2
MIRT057521 CEP55 centrosomal protein 55 2 2
MIRT081129 LDLR low density lipoprotein receptor 2 6
MIRT096817 ZSWIM6 zinc finger SWIM-type containing 6 2 4
MIRT100961 CENPQ centromere protein Q 2 4
MIRT263338 ANAPC16 anaphase promoting complex subunit 16 2 2
MIRT274710 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT311193 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT360127 DEK DEK proto-oncogene 2 2
MIRT438269 PSMD10 proteasome 26S subunit, non-ATPase 10 2 1
MIRT442464 SLC25A13 solute carrier family 25 member 13 2 2
MIRT446110 TSC22D2 TSC22 domain family member 2 2 2
MIRT463119 ZNF507 zinc finger protein 507 2 2
MIRT470566 POU2F1 POU class 2 homeobox 1 2 2
MIRT475059 IVNS1ABP influenza virus NS1A binding protein 2 6
MIRT482538 ACTB actin beta 2 4
MIRT494136 DCAF7 DDB1 and CUL4 associated factor 7 2 6
MIRT495209 EDN3 endothelin 3 2 2
MIRT495235 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT496762 MANBAL mannosidase beta like 2 2
MIRT498885 ZNF12 zinc finger protein 12 2 10
MIRT499280 NBPF11 NBPF member 11 2 2
MIRT507063 H3F3B H3 histone family member 3B 2 2
MIRT508352 HES7 hes family bHLH transcription factor 7 2 8
MIRT510740 SMC1A structural maintenance of chromosomes 1A 2 6
MIRT519872 ZFP62 ZFP62 zinc finger protein 2 4
MIRT521272 RTN4 reticulon 4 2 4
MIRT522324 NFIB nuclear factor I B 2 6
MIRT525011 ACTN4 actinin alpha 4 2 6
MIRT526608 AASDH aminoadipate-semialdehyde dehydrogenase 2 4
MIRT529043 ARL9 ADP ribosylation factor like GTPase 9 2 2
MIRT529545 ZNF678 zinc finger protein 678 2 2
MIRT532500 HOXA13 homeobox A13 2 2
MIRT532599 SIX4 SIX homeobox 4 2 2
MIRT534044 STK4 serine/threonine kinase 4 2 2
MIRT534087 SPPL3 signal peptide peptidase like 3 2 2
MIRT534249 SLC16A1 solute carrier family 16 member 1 2 2
MIRT534286 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534555 RUNX1 runt related transcription factor 1 2 2
MIRT536765 HOXB2 homeobox B2 2 2
MIRT537227 GAN gigaxonin 2 2
MIRT551105 TTC8 tetratricopeptide repeat domain 8 2 2
MIRT552247 DUSP3 dual specificity phosphatase 3 2 2
MIRT554361 SFXN5 sideroflexin 5 2 2
MIRT557402 H3F3C H3 histone family member 3C 2 2
MIRT559116 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT560494 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT562296 GLO1 glyoxalase I 2 2
MIRT562597 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT563857 ALYREF Aly/REF export factor 2 4
MIRT565665 SIX1 SIX homeobox 1 2 2
MIRT568253 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT609593 GPM6B glycoprotein M6B 2 2
MIRT611552 GGT6 gamma-glutamyltransferase 6 2 2
MIRT613451 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT615516 PRRC2A proline rich coiled-coil 2A 2 2
MIRT617766 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT619134 MCOLN3 mucolipin 3 2 2
MIRT621365 CAP2 cyclase associated actin cytoskeleton regulatory protein 2 2 2
MIRT625804 MDC1 mediator of DNA damage checkpoint 1 2 2
MIRT626954 PRDM2 PR/SET domain 2 2 2
MIRT627716 RCAN1 regulator of calcineurin 1 2 2
MIRT628069 KCNJ13 potassium voltage-gated channel subfamily J member 13 2 2
MIRT630451 GTPBP8 GTP binding protein 8 (putative) 2 2
MIRT635533 ELMOD2 ELMO domain containing 2 2 2
MIRT636206 SULF2 sulfatase 2 2 2
MIRT638763 EPHA4 EPH receptor A4 2 2
MIRT640324 STAT1 signal transducer and activator of transcription 1 2 2
MIRT644548 SPOP speckle type BTB/POZ protein 2 2
MIRT645114 TMX2 thioredoxin related transmembrane protein 2 2 2
MIRT647778 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT650112 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT650136 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT650310 SLC35E2 solute carrier family 35 member E2 2 2
MIRT650930 ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2 2
MIRT651018 ZNF740 zinc finger protein 740 2 2
MIRT653541 SLC38A9 solute carrier family 38 member 9 2 2
MIRT655752 NR2C2 nuclear receptor subfamily 2 group C member 2 2 2
MIRT656908 KIAA1958 KIAA1958 2 2
MIRT657854 GJD3 gap junction protein delta 3 2 2
MIRT658215 FBXO21 F-box protein 21 2 2
MIRT659884 CAPN7 calpain 7 2 2
MIRT659922 CACNA1E calcium voltage-gated channel subunit alpha1 E 2 2
MIRT660055 C12orf5 TP53 induced glycolysis regulatory phosphatase 1 1
MIRT664616 LIMD1 LIM domains containing 1 2 2
MIRT665392 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT667887 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT669018 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT688419 DUSP2 dual specificity phosphatase 2 2 2
MIRT691888 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT709530 GEN1 GEN1, Holliday junction 5' flap endonuclease 2 2
MIRT711013 ABCD2 ATP binding cassette subfamily D member 2 2 2
MIRT714731 CENPH centromere protein H 2 2
MIRT719897 PTGIS prostaglandin I2 synthase 2 2
MIRT725028 CX3CL1 C-X3-C motif chemokine ligand 1 2 2
MIRT734348 P2RY12 purinergic receptor P2Y12 3 0
MIRT736719 TNFAIP3 TNF alpha induced protein 3 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-605-5p Navitoclax 24978538 NSC759659 sensitive High Colorectal Cancer cell line (HCT-116, CHL1)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive Low Pancreatic Cancer cell line (BxPC‐3, PANC‐1)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (H358, H1155)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer tissue
hsa-miR-605-5p Fluorouracil 3385 NSC19893 approved resistant Low Colon Cancer cell line (HT-29, LoVo)
hsa-miR-605-5p Everolimus + Panobinostat sensitive Low Clear Cell Renal Cell Carcinoma tissue
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-605-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-605-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-605-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-605-5p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-605-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-605-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-605-5p Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-605-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVCAR3)
hsa-miR-605-5p Cisplatin 5460033 NSC119875 approved resistant cell line (H460)
hsa-miR-605-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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