miRTarBase - #MIRT496840


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pre-miRNA Information
pre-miRNA hsa-mir-3194   
Genomic Coordinates chr20: 51452905 - 51452977
Description Homo sapiens miR-3194 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3194-5p
Sequence 10| GGCCAGCCACCAGGAGGGCUG |30
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1344875175 4 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KCNIP2   
Synonyms KCHIP2
Description potassium voltage-gated channel interacting protein 2
Transcript NM_014591   
Other Transcripts NM_173191 , NM_173192 , NM_173193 , NM_173194 , NM_173195 , NM_173197   
Expression
Putative miRNA Targets on KCNIP2
3'UTR of KCNIP2
(miRNA target sites are highlighted)		 
>KCNIP2|NM_014591|3'UTR
   1 CCCCCAGGAGAGGGGGTCAGTGTTTCCTGGGGGGACCATGCTCTAACCCTAGTCCAGGCGGACCTCACCCTTCTCTTCCC
  81 AGGTCTATCCTCATCCTACGCCTCCCTGGGGGCTGGAGGGATCCAAGAGCTTGGGGATTCAGTAGTCCAGATCTCTGGAG
 161 CTGAAGGGGCCAGAGAGTGGGCAGAGTGCATCTCGGGGGGTGTTCCCAACTCCCACCAGCTCTCACCCCCTTCCTGCCTG
 241 ACACCCAGTGTTGAGAGTGCCCCTCCTGTAGGAATTGAGCGGTTCCCCACCTCCTACCCCTACTCTAGAAACACACTAGA
 321 CAGATGTCTCCTGCTATGGTGCTTCCCCCATCCCTGACCTCATAAACATTTCCCCTAAGACTCCCCTCTCAGAGAGAATG
 401 CTCCATTCTTGGCACTGGCTGGCTTCTCAGACCAGCCATTGAGAGCCCTGTGGGAGGGGGACAAGAATGTATAGGGAGAA
 481 ATCTTGGGCCTGAGTCAATGGATAGGTCCTAGGAGGTGGCTGGGGTTGAGAATAGAAGGGCCTGGACAGATTATGATTGC
 561 TCAGGCATACCAGGTTATAGCTCCAAGTTCCACAGGTCTGCTACCACAGGCCATCAAAATATAAGTTTCCAGGCTTTGCA
 641 GAAGACCTTGTCTCCTTAGAAATGCCCCAGAAATTTTCCACACCCTCCTCGGTATCCATGGAGAGCCTGGGGCCAGATAT
 721 CTGGCTCATCTCTGGCATTGCTTCCTCTCCTTCCTTCCTGCATGTGTTGGTGGTGGTTGTGGTGGGGGAATGTGGATGGG
 801 GGATGTCCTGGCTGATGCCTGCCAAAATTTCATCCCACCCTCCTTGCTTATCGTCCCTGTTTTGAGGGCTATGACTTGAG
 881 TTTTTGTTTCCCATGTTCTCTATAGACTTGGGACCTTCCTGAACTTGGGGCCTATCACTCCCCACAGTGGATGCCTTAGA
 961 AGGGAGAGGGAAGGAGGGAGGCAGGCATAGCATCTGAACCCAGTGTGGGGGCATTCACTAGAATCTTCAATCAACCTGGG
1041 CTCTCCCCACCCCACCCCAGATAACCTCCTCAGTTCCCTAGGGTCTCTTCTTGCTTGACTCAATCTACCCAGAGATGCCC
1121 CTTAGCACACCTAGAGGGCAGGGACCATAGGACCCAGGTTCCAACCCCATTGTCAGCACCCCAGCCATGCGGCCACCCCT
1201 TAGCACACCTGCTCGTCCCATTTAGCTTACCCTCCCAGTTGGCCAGAATCTGAGGGGAGAGCCCCCAGAGAGCCCCCTTC
1281 CCCATCAGAAGACTGTTGACTGCTTTGCATTTTGGGCTCTTCTATATATTTTGTAAAGTAAGAAATATACCAGATCTAAT
1361 AAAACACAATGGCTATGCAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guCGGG---AGGACC---ACCGACCGg 5'
            ||:|   ||:|||   |||||||| 
Target 5' atGCTCCATTCTTGGCACTGGCTGGCt 3'
 398 - 424 163.00 -24.60
2 
miRNA  3' guCGGGAGGACCACCGACCgg 5'
            |||: ||||| ||||||  
Target 5' acGCCTCCCTGGGGGCTGGag 3'
 98 - 118 155.00 -28.50
3 
miRNA  3' gucgggAGGA----CCACCGACCgg 5'
                ||||    |||||||||  
Target 5' gataggTCCTAGGAGGTGGCTGGgg 3'
 501 - 525 141.00 -25.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30183123 2 COSMIC
COSN30490531 37 COSMIC
COSN30137921 40 COSMIC
COSN31509222 53 COSMIC
COSN30100413 60 COSMIC
COSN30462288 78 COSMIC
COSN31608993 90 COSMIC
COSN6053363 98 COSMIC
COSN30151007 99 COSMIC
COSN13249295 108 COSMIC
COSN30150788 184 COSMIC
COSN13249294 195 COSMIC
COSN8525406 226 COSMIC
COSN16128450 255 COSMIC
COSN26577030 280 COSMIC
COSN30173423 1076 COSMIC
COSN28804824 1149 COSMIC
COSN31550623 1154 COSMIC
COSN31603262 1190 COSMIC
COSN30173707 1215 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs545002634 2 dbSNP
rs1292972581 5 dbSNP
rs1308695122 12 dbSNP
rs912832129 13 dbSNP
rs994791089 15 dbSNP
rs897798045 16 dbSNP
rs1232265516 17 dbSNP
rs1254620894 17 dbSNP
rs1332311103 18 dbSNP
rs1294888598 19 dbSNP
rs374733894 20 dbSNP
rs772273918 23 dbSNP
rs748352842 26 dbSNP
rs778918204 28 dbSNP
rs755025719 29 dbSNP
rs188562801 31 dbSNP
rs779959227 33 dbSNP
rs756060646 34 dbSNP
rs1165945939 35 dbSNP
rs1475618293 36 dbSNP
rs750175005 51 dbSNP
rs1014437960 53 dbSNP
rs974209709 56 dbSNP
rs1427136093 57 dbSNP
rs1403597257 59 dbSNP
rs567867726 60 dbSNP
rs962467652 61 dbSNP
rs572944734 68 dbSNP
rs1034498924 73 dbSNP
rs183048405 76 dbSNP
rs1233457939 78 dbSNP
rs72546684 90 dbSNP
rs536377847 99 dbSNP
rs1024235752 100 dbSNP
rs1010120368 108 dbSNP
rs1219703613 110 dbSNP
rs1483712527 111 dbSNP
rs1043460449 133 dbSNP
rs1054326162 134 dbSNP
rs550583002 141 dbSNP
rs1226189585 144 dbSNP
rs946366261 153 dbSNP
rs1305368256 156 dbSNP
rs1000017419 161 dbSNP
rs1156630990 163 dbSNP
rs903960886 170 dbSNP
rs531993035 173 dbSNP
rs1303198349 177 dbSNP
rs564513431 181 dbSNP
rs1314307581 188 dbSNP
rs540141826 194 dbSNP
rs1446690006 195 dbSNP
rs1279563103 196 dbSNP
rs1301197344 197 dbSNP
rs1040170120 198 dbSNP
rs71472588 201 dbSNP
rs942731791 201 dbSNP
rs913544517 204 dbSNP
rs1213356510 205 dbSNP
rs1255701511 212 dbSNP
rs988068210 214 dbSNP
rs965976863 216 dbSNP
rs1301139431 217 dbSNP
rs911737806 218 dbSNP
rs1182628642 222 dbSNP
rs985978681 227 dbSNP
rs2305190 229 dbSNP
rs930266827 235 dbSNP
rs1445685025 244 dbSNP
rs918831523 247 dbSNP
rs1371192970 250 dbSNP
rs1175236542 253 dbSNP
rs753776251 255 dbSNP
rs779904326 261 dbSNP
rs1337006951 265 dbSNP
rs561180535 269 dbSNP
rs756028933 275 dbSNP
rs1014852079 280 dbSNP
rs927080702 281 dbSNP
rs1379568280 312 dbSNP
rs1254566219 314 dbSNP
rs980229469 316 dbSNP
rs1196592267 326 dbSNP
rs1014951219 327 dbSNP
rs775285665 328 dbSNP
rs1436123499 330 dbSNP
rs896052858 341 dbSNP
rs1198034343 346 dbSNP
rs1237524643 352 dbSNP
rs1056407383 353 dbSNP
rs769517105 354 dbSNP
rs1001717448 355 dbSNP
rs1477529122 358 dbSNP
rs1168100243 368 dbSNP
rs1398068550 376 dbSNP
rs1463629056 377 dbSNP
rs542455841 385 dbSNP
rs139950760 393 dbSNP
rs904648669 400 dbSNP
rs1395866938 403 dbSNP
rs1443681342 416 dbSNP
rs1299715323 428 dbSNP
rs190851770 439 dbSNP
rs1032910786 446 dbSNP
rs1000049837 460 dbSNP
rs900305895 469 dbSNP
rs1250663622 480 dbSNP
rs1039800152 483 dbSNP
rs946418546 486 dbSNP
rs1479485888 488 dbSNP
rs913598536 505 dbSNP
rs1265049355 508 dbSNP
rs1450795971 509 dbSNP
rs767601930 515 dbSNP
rs574064384 518 dbSNP
rs911803851 519 dbSNP
rs1169361706 520 dbSNP
rs1322491069 524 dbSNP
rs1292262339 526 dbSNP
rs1463538241 526 dbSNP
rs757468174 540 dbSNP
rs1383154995 551 dbSNP
rs1281326111 553 dbSNP
rs1338729980 557 dbSNP
rs986419872 560 dbSNP
rs777367605 563 dbSNP
rs1230114766 568 dbSNP
rs953243064 569 dbSNP
rs920405526 574 dbSNP
rs929962713 578 dbSNP
rs1336996602 584 dbSNP
rs918861099 602 dbSNP
rs1246961540 626 dbSNP
rs1038563277 629 dbSNP
rs1205510546 650 dbSNP
rs941550216 653 dbSNP
rs1487138277 654 dbSNP
rs1192476302 656 dbSNP
rs1257654119 665 dbSNP
rs1475890807 669 dbSNP
rs1162043432 674 dbSNP
rs973472415 680 dbSNP
rs3209554 681 dbSNP
rs1014904406 682 dbSNP
rs1014255051 683 dbSNP
rs916994596 685 dbSNP
rs1399668881 686 dbSNP
rs960604305 690 dbSNP
rs578071200 691 dbSNP
rs1394397627 701 dbSNP
rs553362652 709 dbSNP
rs1312015538 712 dbSNP
rs904703115 713 dbSNP
rs1021786341 722 dbSNP
rs1239668871 726 dbSNP
rs72546685 734 dbSNP
rs10883689 754 dbSNP
rs1473232388 763 dbSNP
rs1215511000 770 dbSNP
rs1280630622 777 dbSNP
rs1483990350 779 dbSNP
rs763354155 788 dbSNP
rs201384290 789 dbSNP
rs944394858 790 dbSNP
rs890079403 795 dbSNP
rs1420273680 799 dbSNP
rs1181013061 804 dbSNP
rs1050384666 810 dbSNP
rs1378903013 833 dbSNP
rs1008723022 834 dbSNP
rs1174609807 837 dbSNP
rs549579073 840 dbSNP
rs891234039 842 dbSNP
rs1180551229 846 dbSNP
rs1416723008 848 dbSNP
rs1374146645 849 dbSNP
rs1029681952 852 dbSNP
rs931862570 853 dbSNP
rs770971243 857 dbSNP
rs1239163458 859 dbSNP
rs897131743 862 dbSNP
rs537231382 866 dbSNP
rs1207580168 867 dbSNP
rs1254940240 872 dbSNP
rs920457876 877 dbSNP
rs1261069416 878 dbSNP
rs1210338973 890 dbSNP
rs1194670464 893 dbSNP
rs941648940 897 dbSNP
rs973194727 898 dbSNP
rs1260072311 903 dbSNP
rs940820202 913 dbSNP
rs1463612686 914 dbSNP
rs1329353187 920 dbSNP
rs1044989339 933 dbSNP
rs1421230204 940 dbSNP
rs1445936588 945 dbSNP
rs187787385 949 dbSNP
rs950229875 953 dbSNP
rs1217164210 954 dbSNP
rs1313741731 958 dbSNP
rs993281338 968 dbSNP
rs917021658 978 dbSNP
rs1380826019 980 dbSNP
rs765912708 985 dbSNP
rs550426842 988 dbSNP
rs760092818 989 dbSNP
rs1255540507 1007 dbSNP
rs1034732607 1010 dbSNP
rs980405940 1018 dbSNP
rs1458088633 1023 dbSNP
rs968939998 1027 dbSNP
rs747093165 1030 dbSNP
rs1190928032 1037 dbSNP
rs988531513 1038 dbSNP
rs772910930 1046 dbSNP
rs532034658 1050 dbSNP
rs771564503 1056 dbSNP
rs1157277801 1062 dbSNP
rs925571278 1080 dbSNP
rs1423003040 1081 dbSNP
rs747790266 1085 dbSNP
rs1324097393 1090 dbSNP
rs564551236 1092 dbSNP
rs1351494051 1095 dbSNP
rs774345702 1097 dbSNP
rs1292660886 1102 dbSNP
rs182113759 1103 dbSNP
rs987731130 1105 dbSNP
rs1443687325 1121 dbSNP
rs1009040934 1128 dbSNP
rs1234493555 1129 dbSNP
rs1292671393 1143 dbSNP
rs76453795 1149 dbSNP
rs1221304227 1154 dbSNP
rs1190349958 1157 dbSNP
rs1489431292 1158 dbSNP
rs1191738689 1161 dbSNP
rs1447297001 1170 dbSNP
rs1475587107 1182 dbSNP
rs1029714694 1185 dbSNP
rs1050501452 1187 dbSNP
rs772374241 1190 dbSNP
rs931926446 1191 dbSNP
rs899086864 1197 dbSNP
rs1037533017 1214 dbSNP
rs552062133 1215 dbSNP
rs150700247 1221 dbSNP
rs907688781 1222 dbSNP
rs867078933 1226 dbSNP
rs1005539159 1235 dbSNP
rs1203261437 1240 dbSNP
rs1448163717 1248 dbSNP
rs1377700601 1250 dbSNP
rs906131883 1257 dbSNP
rs992938314 1259 dbSNP
rs1356268875 1261 dbSNP
rs1044630811 1267 dbSNP
rs938750594 1270 dbSNP
rs927337950 1280 dbSNP
rs542842465 1287 dbSNP
rs779816271 1294 dbSNP
rs535325560 1311 dbSNP
rs1245321240 1315 dbSNP
rs1052859408 1317 dbSNP
rs1181181759 1319 dbSNP
rs934436077 1322 dbSNP
rs925682887 1324 dbSNP
rs1156570194 1334 dbSNP
rs1021892258 1342 dbSNP
rs989022462 1350 dbSNP
rs1300005593 1365 dbSNP
rs956212810 1370 dbSNP
rs748335163 1375 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC
Disease MIMAT0015078
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020023. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gucgggagGACC---ACCGACCGg 5'
                  :|||   |||||||| 
Target 5' --------UUGGCACUGGCUGGCu 3'
 		1 - 16
Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020023
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000348850.5 | 3UTR | UUGGCACUGGCUGGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.417 0.02 -0.294 0.09 23 Click to see details
UCEC -0.813 0.05 -0.700 0.09 5 Click to see details
PRAD -0.753 0.12 -0.800 0.1 4 Click to see details
LUSC 0.547 0.17 0.500 0.2 5 Click to see details
BRCA -0.38 0.18 -0.548 0.08 8 Click to see details
HNSC 0.592 0.2 0.800 0.1 4 Click to see details
CHOL 0.74 0.23 0.500 0.33 3 Click to see details
STAD -0.222 0.27 -0.236 0.26 10 Click to see details
KIRP 0.33 0.34 0.400 0.3 4 Click to see details
THCA 0.077 0.37 0.015 0.47 22 Click to see details
KIRC 0.118 0.44 0.400 0.3 4 Click to see details
KICH 0.022 0.49 -0.100 0.44 5 Click to see details
KICH 0.022 0.49 -0.100 0.44 5 Click to see details
KICH 0.022 0.49 -0.100 0.44 5 Click to see details
72 hsa-miR-3194-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT443250 C9orf170 chromosome 9 open reading frame 170 2 2
MIRT443284 ZC3H12A zinc finger CCCH-type containing 12A 2 2
MIRT461518 EMC7 ER membrane protein complex subunit 7 2 2
MIRT466738 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT467651 SLC7A1 solute carrier family 7 member 1 2 2
MIRT472998 MRPS23 mitochondrial ribosomal protein S23 2 4
MIRT477911 DUSP2 dual specificity phosphatase 2 2 2
MIRT480853 BLCAP bladder cancer associated protein 2 2
MIRT482890 IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog 2 4
MIRT487295 SLC38A9 solute carrier family 38 member 9 2 2
MIRT488494 SFMBT2 Scm like with four mbt domains 2 2 4
MIRT489060 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT491209 MLLT1 MLLT1, super elongation complex subunit 2 4
MIRT491479 APC2 APC2, WNT signaling pathway regulator 2 8
MIRT492558 PRX periaxin 2 6
MIRT495499 SLC39A2 solute carrier family 39 member 2 2 2
MIRT496578 ZNF280D zinc finger protein 280D 2 2
MIRT496840 KCNIP2 potassium voltage-gated channel interacting protein 2 2 2
MIRT497840 CHD1 chromodomain helicase DNA binding protein 1 2 2
MIRT499396 PLCG2 phospholipase C gamma 2 2 7
MIRT503237 C16orf74 chromosome 16 open reading frame 74 2 4
MIRT512345 ZNF665 zinc finger protein 665 2 4
MIRT512527 ATCAY ATCAY, caytaxin 2 4
MIRT513160 PPIB peptidylprolyl isomerase B 2 2
MIRT514493 STOML1 stomatin like 1 2 2
MIRT517164 SLC28A1 solute carrier family 28 member 1 2 2
MIRT520463 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT524151 DIP2A disco interacting protein 2 homolog A 2 2
MIRT530324 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT533747 TMEM184B transmembrane protein 184B 2 2
MIRT534259 SLC12A7 solute carrier family 12 member 7 2 2
MIRT561273 ZDHHC18 zinc finger DHHC-type containing 18 2 2
MIRT569126 TMC5 transmembrane channel like 5 2 4
MIRT569937 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT570073 VPS8 VPS8, CORVET complex subunit 2 2
MIRT570636 KLF13 Kruppel like factor 13 2 2
MIRT571026 CENPP centromere protein P 2 2
MIRT573838 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT574899 Plcg2 phospholipase C, gamma 2 2 5
MIRT576070 Poteg POTE ankyrin domain family, member G 2 2
MIRT576753 Tmem127 transmembrane protein 127 2 2
MIRT611795 WNT9A Wnt family member 9A 2 2
MIRT616756 SVOP SV2 related protein 2 2
MIRT630965 NGDN neuroguidin 2 2
MIRT634555 LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2 2
MIRT638646 GK5 glycerol kinase 5 (putative) 2 2
MIRT639903 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2 2
MIRT640529 TET3 tet methylcytosine dioxygenase 3 2 4
MIRT644529 TMEM134 transmembrane protein 134 2 2
MIRT644887 C2orf50 chromosome 2 open reading frame 50 2 2
MIRT647729 CXCR2 C-X-C motif chemokine receptor 2 2 2
MIRT648086 FAM192A family with sequence similarity 192 member A 2 2
MIRT650808 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT660505 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT667193 NODAL nodal growth differentiation factor 2 2
MIRT685675 PSMB7 proteasome subunit beta 7 2 2
MIRT692710 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT693598 SLC39A1 solute carrier family 39 member 1 2 2
MIRT698059 TRIOBP TRIO and F-actin binding protein 2 2
MIRT698292 TMEM2 transmembrane protein 2 2 2
MIRT702353 KLHL26 kelch like family member 26 2 2
MIRT708623 NUDT18 nudix hydrolase 18 2 2
MIRT714289 KBTBD11 kelch repeat and BTB domain containing 11 2 2
MIRT714577 WDR41 WD repeat domain 41 2 2
MIRT716734 APOL6 apolipoprotein L6 2 2
MIRT718781 RAC3 Rac family small GTPase 3 2 2
MIRT720973 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT720986 TOM1 target of myb1 membrane trafficking protein 2 2
MIRT721391 LDLRAD4 low density lipoprotein receptor class A domain containing 4 2 2
MIRT722905 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT723205 ZNRF1 zinc and ring finger 1 2 2
MIRT725431 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3194 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-3194 Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-3194 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-3194 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-3194-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3194-5p Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-3194-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-3194-5p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-3194-5p Cisplatin 5460033 NSC119875 approved resistant Low Hepatocellular Carcinoma cell line (HepG2)
hsa-miR-3194-5p Temozolomide 5394 NSC362856 approved resistant High Glioblastoma cell line (A172)
hsa-miR-3194-5p Estradiol 5757 NSC9895 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3194-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3194-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-3194-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-3194-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-3194-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-3194-5p Platinum 23939 resistant tissue
hsa-miR-3194-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3194-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3194-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-3194-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-3194-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MDAH-2774)
hsa-miR-3194-5p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)
hsa-miR-3194-5p Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

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