miRTarBase - #MIRT496992


—
pre-miRNA Information
pre-miRNA hsa-mir-371b   
Genomic Coordinates chr19: 53787677 - 53787742
Description Homo sapiens miR-371b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-371b-3p
Sequence 43| AAGUGCCCCCACAGUUUGAGUGC |65
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 19 - 53787699 16594986 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1345825760 2 dbSNP
rs922443786 5 dbSNP
rs773769548 6 dbSNP
rs1034874198 8 dbSNP
rs772543475 9 dbSNP
rs1318684148 10 dbSNP
rs1004685112 12 dbSNP
rs1402402708 12 dbSNP
rs1427092890 13 dbSNP
rs1202234248 14 dbSNP
rs770734168 14 dbSNP
rs1428290628 15 dbSNP
rs1480794990 15 dbSNP
rs1049004182 17 dbSNP
rs1185000692 19 dbSNP
rs748499899 22 dbSNP
rs1487511363 23 dbSNP
Putative Targets

Gene Information
Gene Symbol TMEM231   
Synonyms ALYE870, JBTS20, MKS11, PRO1886
Description transmembrane protein 231
Transcript NM_001077418   
Other Transcripts NM_001077416   
Expression
Putative miRNA Targets on TMEM231
3'UTR of TMEM231
(miRNA target sites are highlighted)		 
>TMEM231|NM_001077418|3'UTR
   1 AAAGGCCATTTCTGAAGACTCAGCAGGACCGTGGCTGCCTCATTGTCATCTTCTGGGAACATCTTAGGACCTTTTGAAAG
  81 AGCCCAGCGGACACCTGCGGGCTTGTGTGCTTTTCCCTCAGAGACAACGGTTCTTTCCGGTTTTGCTCTACACAGTTCCG
 161 TATCTTCAGAGCTCCTGCAGAATTGTCAGGGACTAGTTTGTGGAAAGGTCTGAGAGTTCCTGGAGGCTATAATTAGCTTT
 241 TTGGGTTTTCCTTCTTTGCCTTAGCGTTGAATTTCAGGAGAAAATTGCAGTCAGTTCAGACATCTTGGAAAGAGTCCCAT
 321 CTCTGGTCAAGCAGAGACTTTTCCTCTGTTGAACTGAGGAACACACTGTGCATTTCTACCTTCTGTTGTGAGCCACTCTT
 401 ACTCTTTTCAGGGCTCTCTTGTGACAAACATGCCAATCACTAGCACTTTGCACCCCTGGGCTTCTCCATTTCCCATTCAC
 481 AGCTTTGATTTCCAGAGCTGAGGCCTTTAACTGGAGACCTGGAGGGGCAGGGCCCAAGGGCAAGGGCCGCATTAGCACAG
 561 GCAATCAGGGAGGGCCGCTGAAGGACACTTGGACCGTCCACCTGCCCCAGCCCAACAGTCAGTCATCTGTCATCAGCTCA
 641 GCTGAGCAGCCCTGGATCTTTGCCGTACTGTGACTGGGCTCTTTGCCCTATTTTTCCCTCTGTCTGTGCCCCTGGATGGC
 721 AGGCTGAAGTCAGAGGGGCTGTTTCATTCTCAGCCCCCTCAGCAGCACTGGGGGAAGAAAGCATTGTCACAACAGGTTCT
 801 TTCTGGCCCTCACCCAACAGCCTGGGCACTTGGCCCTCCTCCTCCTTGACAGCCCTCCCCCTTCCTGCAAAGGACAGGGG
 881 CGACAGGGGTTGGTGTTGGGATTGGCTCCCGCTGCCTGACAACCACAAGTTTATTTGGAAGGCTAGCGGGAAGCCCAGCG
 961 GCTGGCGTTTCCCTTGACTAAGGAACAGGGTGCCCATCAGAGTGGGGCGGGCAGCTTTGGGAAGGACACAAGAAGCAGTA
1041 AGAGTGTAAAGAGGATGCTGGCCTGGGCAGGCCAGTCCAGCCTGGCCACTAGCAGAATACCAAGCAGTCCAGTGGATTAC
1121 CCTCGTGGCTAAGCAAGTGTCTGCAGGAGCAGAGATGGCTGGAAGGGGCCTCTGCACACGGAAGATGGCTTGTTCAGCCC
1201 ATTCACCTCCTGAGGATGTGGGCAGTCTCCTCCAAGAACACATGGAGCTGCTTCCTGATCCCAAGCAGGTCATTGCCACT
1281 GGAAGGACATGGCCCCGGTGATCCATGCTTCATGCCCACCCAGAAACACACCCCTCAGTGTGTGCCTCAGTTTACTTTGG
1361 AGATCAGTTGTCGTTTTTAGTGCTCCTTTAGGCTTACTAAAACAGTTTTGGAAACAAAGCTATTTTGAAGTATTCAAGCA
1441 GAGGAATTCCCTAACACTGACCCCCTTGTCTTTTTTTAATATTCAGGCTGTTTTATATGCCTAAATTTTTTTCTTAAGAT
1521 CTAAACGAAAAATAGTTTCTTGTTTAAATTCACATAAGGCAATGAGATATGGAAAGATGACAAGATACGTATAAACATTG
1601 GTTTGCATTTTATTAAATTATTCTAATGCAAATCTTGTATAAAGAACCCATGATGTTTTGTAACTTTCTAATTAAAATGT
1681 TCAAAATGAGGCCGAGCATGGTGGTTCATTCCTGTAATCTCAACACTTTGGGAGGCCAAGGTGGGAGGATCACTTGAGCC
1761 CAGGAGCTTGAGGCTGCAGTGTGCTATGATTGCACCACTGTACTGTAGCCTGGGTGACAGAGTGAGACCCTATCTGTTAA
1841 AATAAATAAATAAATAAATAAAAAAGTCAAAATGGAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cguGAGU---UUGACACCCCCGUGAa 5'
             ||||   ||| |   ||||||| 
Target 5' gccCTCACCCAACAGCCTGGGCACTt 3'
 806 - 831 156.00 -15.80
2 
miRNA  3' cgugAGUUUGACACC-CCCGU-GAa 5'
              |||:| || || ||||| || 
Target 5' cccaTCAGAGTGGGGCGGGCAGCTt 3'
 993 - 1017 135.00 -19.10
3 
miRNA  3' cgugaGUUUGACAC--CCCCGUGAa 5'
               |: ||||||   |||| || 
Target 5' tttgcCGTACTGTGACTGGGCTCTt 3'
 659 - 683 128.00 -17.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
257328 8 ClinVar
157371 2644 ClinVar
COSN30463173 7 COSMIC
COSN8865878 8 COSMIC
COSN14897719 31 COSMIC
COSN30122521 34 COSMIC
COSN30476411 47 COSMIC
COSN31585369 50 COSMIC
COSN31569539 72 COSMIC
COSN27154021 117 COSMIC
COSN6094314 159 COSMIC
COSN29144171 212 COSMIC
COSN19332568 378 COSMIC
COSN25207398 478 COSMIC
COSN6647278 986 COSMIC
COSN15685367 1135 COSMIC
COSN20113108 1398 COSMIC
COSN27462974 1839 COSMIC
COSN23751612 2058 COSMIC
COSN9221669 2341 COSMIC
COSN24564488 2503 COSMIC
COSN16856164 2860 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1392030855 5 dbSNP
rs1190508532 7 dbSNP
rs2242407 8 dbSNP
rs764569993 10 dbSNP
rs1189219335 12 dbSNP
rs537143676 19 dbSNP
rs1292076682 20 dbSNP
rs1487612580 22 dbSNP
rs773011638 22 dbSNP
rs995468947 27 dbSNP
rs764154853 29 dbSNP
rs200390475 30 dbSNP
rs1690507 31 dbSNP
rs1195773509 35 dbSNP
rs766191939 37 dbSNP
rs760584160 42 dbSNP
rs1346482960 43 dbSNP
rs773194449 45 dbSNP
rs1428062165 50 dbSNP
rs118186772 55 dbSNP
rs940085065 57 dbSNP
rs557848296 61 dbSNP
rs139090728 69 dbSNP
rs146695973 71 dbSNP
rs1471824069 74 dbSNP
rs1384705417 81 dbSNP
rs549226245 84 dbSNP
rs1189385385 85 dbSNP
rs927178924 88 dbSNP
rs979794662 89 dbSNP
rs1451558742 92 dbSNP
rs1315076329 94 dbSNP
rs947017198 96 dbSNP
rs1226603551 98 dbSNP
rs371104425 99 dbSNP
rs531630294 100 dbSNP
rs1215772149 101 dbSNP
rs1245268946 102 dbSNP
rs914229594 107 dbSNP
rs1488321187 110 dbSNP
rs1246488237 116 dbSNP
rs1206551606 119 dbSNP
rs1446243000 121 dbSNP
rs1253225098 129 dbSNP
rs997364358 133 dbSNP
rs1182142811 134 dbSNP
rs749624162 137 dbSNP
rs2242408 138 dbSNP
rs459211 139 dbSNP
rs1008482081 140 dbSNP
rs887318013 145 dbSNP
rs1047351711 146 dbSNP
rs1019795313 149 dbSNP
rs1299694192 153 dbSNP
rs549889487 155 dbSNP
rs954324357 158 dbSNP
rs1293890764 159 dbSNP
rs1356168270 160 dbSNP
rs756284419 160 dbSNP
rs1287919969 167 dbSNP
rs1037435843 169 dbSNP
rs995751045 170 dbSNP
rs1366892016 174 dbSNP
rs1205615656 186 dbSNP
rs1253415838 189 dbSNP
rs898538992 191 dbSNP
rs1015586208 193 dbSNP
rs1205061655 199 dbSNP
rs1258915255 212 dbSNP
rs1475865497 216 dbSNP
rs532869843 217 dbSNP
rs1179624325 219 dbSNP
rs1295001083 225 dbSNP
rs1412565614 228 dbSNP
rs915736339 229 dbSNP
rs1056932019 231 dbSNP
rs1430409942 234 dbSNP
rs1004328851 244 dbSNP
rs1326048495 245 dbSNP
rs1428944722 249 dbSNP
rs896533593 250 dbSNP
rs924505898 256 dbSNP
rs1056984292 263 dbSNP
rs938474588 265 dbSNP
rs905786494 266 dbSNP
rs1044321843 276 dbSNP
rs1378588322 281 dbSNP
rs977329145 282 dbSNP
rs1298075333 285 dbSNP
rs201848505 285 dbSNP
rs564136387 287 dbSNP
rs1474925052 299 dbSNP
rs1486966596 303 dbSNP
rs1207370872 317 dbSNP
rs947301752 328 dbSNP
rs1247069914 342 dbSNP
rs1485918471 361 dbSNP
rs1187843299 362 dbSNP
rs914260699 364 dbSNP
rs1448630580 367 dbSNP
rs752805455 368 dbSNP
rs1052693063 372 dbSNP
rs201560860 378 dbSNP
rs968732077 388 dbSNP
rs1333453514 396 dbSNP
rs912262524 402 dbSNP
rs1431576195 407 dbSNP
rs1322798461 413 dbSNP
rs914586709 436 dbSNP
rs1205216516 446 dbSNP
rs1343720118 451 dbSNP
rs986997167 452 dbSNP
rs954391293 467 dbSNP
rs975516570 468 dbSNP
rs921439857 469 dbSNP
rs964515732 472 dbSNP
rs974346161 476 dbSNP
rs1213643810 478 dbSNP
rs962944133 478 dbSNP
rs1464192247 480 dbSNP
rs1193911700 481 dbSNP
rs1346075521 482 dbSNP
rs1015615607 485 dbSNP
rs1171862984 491 dbSNP
rs1434839304 492 dbSNP
rs1401342404 504 dbSNP
rs1004191507 508 dbSNP
rs1386682911 511 dbSNP
rs960824922 513 dbSNP
rs1326848285 525 dbSNP
rs1333125319 537 dbSNP
rs1345414495 548 dbSNP
rs1352099987 549 dbSNP
rs1229666476 552 dbSNP
rs1265651402 555 dbSNP
rs1035480801 557 dbSNP
rs1309201160 560 dbSNP
rs1411679668 564 dbSNP
rs1002283439 566 dbSNP
rs1368803438 572 dbSNP
rs527245423 575 dbSNP
rs867055010 576 dbSNP
rs1044189241 577 dbSNP
rs1233361022 583 dbSNP
rs1011462552 585 dbSNP
rs1479357348 593 dbSNP
rs1179958063 595 dbSNP
rs1016374921 596 dbSNP
rs561970164 598 dbSNP
rs1483717718 601 dbSNP
rs1230686547 603 dbSNP
rs1165923016 610 dbSNP
rs1393224453 616 dbSNP
rs1203292813 617 dbSNP
rs1403934525 624 dbSNP
rs1052724068 626 dbSNP
rs934288310 629 dbSNP
rs1217790529 632 dbSNP
rs1287017650 633 dbSNP
rs1349263194 634 dbSNP
rs1285575266 637 dbSNP
rs1323296225 638 dbSNP
rs912222966 644 dbSNP
rs1208983436 650 dbSNP
rs542097304 654 dbSNP
rs379929 659 dbSNP
rs932402068 660 dbSNP
rs1251079830 663 dbSNP
rs921461558 664 dbSNP
rs576348684 665 dbSNP
rs364062 666 dbSNP
rs572916705 669 dbSNP
rs1206268917 672 dbSNP
rs1332477495 673 dbSNP
rs1487015287 673 dbSNP
rs1284342612 679 dbSNP
rs1432021233 683 dbSNP
rs975781530 685 dbSNP
rs414304 689 dbSNP
rs397832270 690 dbSNP
rs369871878 697 dbSNP
rs951507386 698 dbSNP
rs1025844443 702 dbSNP
rs961023023 703 dbSNP
rs1344039411 706 dbSNP
rs1473531236 708 dbSNP
rs1273803286 724 dbSNP
rs1485982607 734 dbSNP
rs562532016 735 dbSNP
rs1258293015 738 dbSNP
rs1010325985 749 dbSNP
rs1440785044 753 dbSNP
rs1187024176 754 dbSNP
rs1391089211 761 dbSNP
rs543926691 768 dbSNP
rs578051832 772 dbSNP
rs1023890265 774 dbSNP
rs969484808 777 dbSNP
rs1012970180 803 dbSNP
rs1318557629 817 dbSNP
rs1366978667 821 dbSNP
rs1472866144 823 dbSNP
rs1432601570 825 dbSNP
rs1022773284 827 dbSNP
rs1011327100 834 dbSNP
rs1235250269 835 dbSNP
rs893064815 846 dbSNP
rs1342956786 859 dbSNP
rs1053002387 860 dbSNP
rs1461096905 861 dbSNP
rs1247739438 862 dbSNP
rs1434127480 864 dbSNP
rs1178868309 877 dbSNP
rs998781585 878 dbSNP
rs903017559 881 dbSNP
rs890810893 882 dbSNP
rs1211032609 885 dbSNP
rs772670580 887 dbSNP
rs529952725 888 dbSNP
rs1352519170 889 dbSNP
rs947244777 892 dbSNP
rs932406782 894 dbSNP
rs1039636730 897 dbSNP
rs1330497454 905 dbSNP
rs1381460453 908 dbSNP
rs558198722 911 dbSNP
rs1331342817 915 dbSNP
rs1206992708 918 dbSNP
rs912590997 922 dbSNP
rs1489005692 933 dbSNP
rs1193339296 947 dbSNP
rs1038550256 948 dbSNP
rs1452199270 953 dbSNP
rs1389751966 957 dbSNP
rs974606474 959 dbSNP
rs1157951051 960 dbSNP
rs1350169092 962 dbSNP
rs1291609857 966 dbSNP
rs191389392 967 dbSNP
rs908702329 970 dbSNP
rs983476488 978 dbSNP
rs364229 986 dbSNP
rs1287944260 990 dbSNP
rs186746735 995 dbSNP
rs1224095518 996 dbSNP
rs1263997982 997 dbSNP
rs991113327 1001 dbSNP
rs1206414726 1008 dbSNP
rs927981829 1009 dbSNP
rs1035353927 1012 dbSNP
rs1425144045 1022 dbSNP
rs1162281512 1025 dbSNP
rs74027411 1027 dbSNP
rs969448776 1029 dbSNP
rs967062637 1031 dbSNP
rs1022304657 1033 dbSNP
rs1190873204 1035 dbSNP
rs989517772 1040 dbSNP
rs957240982 1043 dbSNP
rs1222966106 1045 dbSNP
rs1297645591 1054 dbSNP
rs1043661 1061 dbSNP
rs1031447756 1067 dbSNP
rs1020000645 1070 dbSNP
rs2650396 1072 dbSNP
rs1310854557 1074 dbSNP
rs1321494316 1074 dbSNP
rs1289680369 1086 dbSNP
rs1229679007 1087 dbSNP
rs1277368590 1091 dbSNP
rs2738789 1099 dbSNP
rs142396278 1100 dbSNP
rs2738790 1101 dbSNP
rs386792189 1102 dbSNP
rs1483953365 1103 dbSNP
rs996485253 1106 dbSNP
rs1006837270 1110 dbSNP
rs1449825300 1111 dbSNP
rs1383668617 1116 dbSNP
rs448629 1120 dbSNP
rs1428976741 1124 dbSNP
rs1038160075 1125 dbSNP
rs1288144175 1127 dbSNP
rs111432981 1129 dbSNP
rs773177729 1132 dbSNP
rs1382369553 1135 dbSNP
rs887295151 1135 dbSNP
rs1047213479 1137 dbSNP
rs939610085 1138 dbSNP
rs1351601512 1143 dbSNP
rs1340508407 1147 dbSNP
rs928201077 1151 dbSNP
rs1228233318 1159 dbSNP
rs1279953757 1162 dbSNP
rs865978768 1169 dbSNP
rs1161106483 1174 dbSNP
rs1423494502 1175 dbSNP
rs2641800 1179 dbSNP
rs1170117072 1180 dbSNP
rs1236507036 1186 dbSNP
rs948092948 1186 dbSNP
rs915241544 1187 dbSNP
rs1190140663 1189 dbSNP
rs1245906250 1192 dbSNP
rs113745185 1197 dbSNP
rs388223 1200 dbSNP
rs1191699628 1202 dbSNP
rs1192206930 1206 dbSNP
rs1427258145 1207 dbSNP
rs956775106 1209 dbSNP
rs548542490 1219 dbSNP
rs977260018 1220 dbSNP
rs955472366 1221 dbSNP
rs1457921355 1222 dbSNP
rs1322818123 1223 dbSNP
rs1363382106 1237 dbSNP
rs1430543813 1239 dbSNP
rs531489004 1242 dbSNP
rs575960202 1244 dbSNP
rs1221809023 1246 dbSNP
rs1261919827 1249 dbSNP
rs1174555955 1259 dbSNP
rs1343008475 1262 dbSNP
rs941508314 1264 dbSNP
rs916786219 1265 dbSNP
rs991474049 1272 dbSNP
rs369553172 1278 dbSNP
rs1248353687 1286 dbSNP
rs960984513 1291 dbSNP
rs2550889 1294 dbSNP
rs963745956 1296 dbSNP
rs6564264 1297 dbSNP
rs1005332961 1305 dbSNP
rs967031348 1311 dbSNP
rs1347288430 1316 dbSNP
rs1386796998 1318 dbSNP
rs1020429746 1332 dbSNP
rs1301249005 1335 dbSNP
rs1352010119 1338 dbSNP
rs1434873288 1340 dbSNP
rs886827330 1346 dbSNP
rs1403741942 1356 dbSNP
rs532295565 1361 dbSNP
rs1229760456 1367 dbSNP
rs181236075 1370 dbSNP
rs1003683021 1371 dbSNP
rs957418844 1372 dbSNP
rs772288415 1373 dbSNP
rs891007695 1382 dbSNP
rs1051014674 1383 dbSNP
rs1252529502 1385 dbSNP
rs1483414112 1387 dbSNP
rs746018219 1391 dbSNP
rs1177218808 1392 dbSNP
rs149564184 1395 dbSNP
rs2550888 1397 dbSNP
rs915272391 1399 dbSNP
rs1038851748 1400 dbSNP
rs554028947 1403 dbSNP
rs1483382365 1408 dbSNP
rs1053686043 1415 dbSNP
rs895301883 1422 dbSNP
rs1305597239 1427 dbSNP
rs1334681190 1428 dbSNP
rs1244992343 1431 dbSNP
rs1285597918 1435 dbSNP
rs1055260825 1440 dbSNP
rs15957 1445 dbSNP
rs1480415811 1446 dbSNP
rs1256850047 1449 dbSNP
rs542144691 1450 dbSNP
rs1202967439 1454 dbSNP
rs368601790 1455 dbSNP
rs138251678 1456 dbSNP
rs1239491990 1458 dbSNP
rs978331549 1458 dbSNP
rs183693704 1460 dbSNP
rs751798303 1461 dbSNP
rs1391204698 1463 dbSNP
rs1432114465 1465 dbSNP
rs912925713 1481 dbSNP
rs1395058077 1485 dbSNP
rs570975227 1486 dbSNP
rs1396169982 1491 dbSNP
rs1330298391 1497 dbSNP
rs922425784 1505 dbSNP
rs553952796 1507 dbSNP
rs756576974 1513 dbSNP
rs1016622526 1514 dbSNP
rs564257664 1526 dbSNP
rs1018441760 1527 dbSNP
rs951215673 1528 dbSNP
rs1338812303 1533 dbSNP
rs1201157932 1537 dbSNP
rs985255959 1539 dbSNP
rs1025427747 1542 dbSNP
rs1473195653 1546 dbSNP
rs955203903 1554 dbSNP
rs1029569443 1560 dbSNP
rs1451723691 1562 dbSNP
rs994115787 1570 dbSNP
rs1003703653 1572 dbSNP
rs147486783 1580 dbSNP
rs548231964 1581 dbSNP
rs1173857793 1584 dbSNP
rs1399470863 1586 dbSNP
rs1045627541 1588 dbSNP
rs143077806 1589 dbSNP
rs1462435124 1592 dbSNP
rs1367091960 1605 dbSNP
rs112178223 1609 dbSNP
rs895197684 1612 dbSNP
rs1055633042 1614 dbSNP
rs1257787645 1617 dbSNP
rs939499273 1625 dbSNP
rs1261019937 1630 dbSNP
rs569069130 1637 dbSNP
rs753226212 1638 dbSNP
rs1042605255 1639 dbSNP
rs571479922 1640 dbSNP
rs935299096 1641 dbSNP
rs552403824 1648 dbSNP
rs945665763 1654 dbSNP
rs532254815 1655 dbSNP
rs1426509431 1657 dbSNP
rs1281255825 1658 dbSNP
rs923928695 1668 dbSNP
rs989789987 1682 dbSNP
rs1051894839 1683 dbSNP
rs1288030913 1692 dbSNP
rs1334686314 1693 dbSNP
rs559906710 1694 dbSNP
rs541163217 1695 dbSNP
rs922486988 1701 dbSNP
rs1343713554 1702 dbSNP
rs975213356 1703 dbSNP
rs1312922062 1705 dbSNP
rs1454238874 1707 dbSNP
rs527758783 1708 dbSNP
rs549239179 1719 dbSNP
rs561817442 1719 dbSNP
rs1260452548 1720 dbSNP
rs139115967 1721 dbSNP
rs1212152012 1723 dbSNP
rs576345067 1724 dbSNP
rs751220821 1725 dbSNP
rs1490038473 1734 dbSNP
rs374432142 1735 dbSNP
rs1413572612 1736 dbSNP
rs765995551 1739 dbSNP
rs1025716034 1746 dbSNP
rs1127396 1752 dbSNP
rs955181043 1755 dbSNP
rs557845616 1761 dbSNP
rs150149418 1766 dbSNP
rs1185571430 1770 dbSNP
rs1442997638 1772 dbSNP
rs772842541 1783 dbSNP
rs1242818846 1786 dbSNP
rs765145397 1795 dbSNP
rs1182721133 1796 dbSNP
rs1404373407 1799 dbSNP
rs55722812 1803 dbSNP
rs1286204609 1810 dbSNP
rs1222214550 1814 dbSNP
rs1023778059 1816 dbSNP
rs1012331180 1820 dbSNP
rs1322686397 1821 dbSNP
rs113282810 1825 dbSNP
rs180751996 1827 dbSNP
rs1359300711 1828 dbSNP
rs1005523059 1829 dbSNP
rs895157517 1833 dbSNP
rs148072778 1851 dbSNP
rs1380078527 1853 dbSNP
rs766595952 1855 dbSNP
rs1313962690 1859 dbSNP
rs1003611452 1860 dbSNP
rs114880995 1863 dbSNP
rs1161482792 1863 dbSNP
rs201679912 1863 dbSNP
rs377633220 1863 dbSNP
rs906701966 1863 dbSNP
rs902535845 1865 dbSNP
rs1297804139 1866 dbSNP
rs1380223635 1866 dbSNP
rs537448937 1867 dbSNP
rs1382515748 1870 dbSNP
rs1229707111 1873 dbSNP
rs933431633 1874 dbSNP
rs878873915 1876 dbSNP
rs2550887 1880 dbSNP
rs1305242521 1884 dbSNP
rs1039558297 1885 dbSNP
rs1256192818 1889 dbSNP
rs1484004188 1890 dbSNP
rs552230338 1896 dbSNP
rs909716651 1897 dbSNP
rs984063601 1898 dbSNP
rs189512182 1903 dbSNP
rs1049499454 1904 dbSNP
rs918272180 1906 dbSNP
rs1190421767 1908 dbSNP
rs1417359509 1916 dbSNP
rs1408251310 1919 dbSNP
rs566359435 1922 dbSNP
rs982162648 1927 dbSNP
rs80329655 1928 dbSNP
rs922351489 1942 dbSNP
rs1475588135 1945 dbSNP
rs749679427 1948 dbSNP
rs1436349848 1951 dbSNP
rs972527858 1953 dbSNP
rs529804131 1954 dbSNP
rs2550886 1969 dbSNP
rs1214532521 1972 dbSNP
rs1301297608 1985 dbSNP
rs184738641 1986 dbSNP
rs531652252 1989 dbSNP
rs79096003 1996 dbSNP
rs1262184559 1998 dbSNP
rs377684156 1999 dbSNP
rs748313535 2002 dbSNP
rs1356671128 2005 dbSNP
rs1240174316 2013 dbSNP
rs1475017350 2014 dbSNP
rs999809729 2018 dbSNP
rs1191718766 2019 dbSNP
rs902732764 2030 dbSNP
rs984468892 2031 dbSNP
rs1174527466 2039 dbSNP
rs1290509690 2046 dbSNP
rs1405687386 2051 dbSNP
rs1458063125 2056 dbSNP
rs1320640663 2059 dbSNP
rs756484906 2067 dbSNP
rs959386636 2071 dbSNP
rs1430569775 2073 dbSNP
rs997885874 2075 dbSNP
rs1346836013 2077 dbSNP
rs781259130 2077 dbSNP
rs1221206948 2081 dbSNP
rs1282211112 2082 dbSNP
rs1329373158 2083 dbSNP
rs1225142898 2090 dbSNP
rs1281815880 2093 dbSNP
rs1446222507 2094 dbSNP
rs1222216304 2095 dbSNP
rs1341118931 2096 dbSNP
rs1033674713 2097 dbSNP
rs1197409922 2100 dbSNP
rs1428716169 2104 dbSNP
rs374235875 2110 dbSNP
rs1227221358 2112 dbSNP
rs970746612 2115 dbSNP
rs1305523533 2128 dbSNP
rs1020999996 2142 dbSNP
rs1166080954 2144 dbSNP
rs1368050611 2145 dbSNP
rs1403672451 2149 dbSNP
rs1403131991 2152 dbSNP
rs1350590317 2158 dbSNP
rs1365054309 2159 dbSNP
rs546212047 2162 dbSNP
rs1349670318 2170 dbSNP
rs577589228 2183 dbSNP
rs1411867851 2184 dbSNP
rs893982945 2188 dbSNP
rs1039178146 2193 dbSNP
rs748589584 2198 dbSNP
rs1165921338 2199 dbSNP
rs888312097 2210 dbSNP
rs1008261817 2211 dbSNP
rs1048229710 2213 dbSNP
rs781715408 2214 dbSNP
rs929928860 2217 dbSNP
rs1163514337 2218 dbSNP
rs547691274 2219 dbSNP
rs981810111 2220 dbSNP
rs922318678 2223 dbSNP
rs754461703 2224 dbSNP
rs916244663 2227 dbSNP
rs990552014 2229 dbSNP
rs957770114 2230 dbSNP
rs925465208 2243 dbSNP
rs113131344 2244 dbSNP
rs966988415 2257 dbSNP
rs1197671848 2258 dbSNP
rs939852732 2261 dbSNP
rs765945095 2262 dbSNP
rs193203276 2263 dbSNP
rs1184455391 2264 dbSNP
rs997777263 2270 dbSNP
rs113257643 2271 dbSNP
rs964732426 2272 dbSNP
rs1017604741 2287 dbSNP
rs1183508709 2294 dbSNP
rs1006322656 2295 dbSNP
rs887840535 2302 dbSNP
rs188344732 2305 dbSNP
rs554753907 2306 dbSNP
rs1220876006 2307 dbSNP
rs537937750 2310 dbSNP
rs1414621454 2311 dbSNP
rs1046783492 2315 dbSNP
rs575166497 2317 dbSNP
rs1403628255 2319 dbSNP
rs916274246 2321 dbSNP
rs755151624 2322 dbSNP
rs1054687412 2337 dbSNP
rs936442483 2342 dbSNP
rs1268433631 2344 dbSNP
rs1338833765 2346 dbSNP
rs924993951 2355 dbSNP
rs958225062 2356 dbSNP
rs140243459 2359 dbSNP
rs1203473929 2360 dbSNP
rs114698798 2361 dbSNP
rs1007731189 2372 dbSNP
rs146656882 2376 dbSNP
rs546447547 2379 dbSNP
rs976769866 2383 dbSNP
rs1480516595 2386 dbSNP
rs964930433 2395 dbSNP
rs1426827775 2402 dbSNP
rs1017639008 2404 dbSNP
rs377013428 2405 dbSNP
rs1006188485 2420 dbSNP
rs952118783 2421 dbSNP
rs1026851674 2422 dbSNP
rs997829028 2423 dbSNP
rs993592486 2426 dbSNP
rs185026929 2430 dbSNP
rs1317639321 2432 dbSNP
rs900864110 2433 dbSNP
rs1470890607 2438 dbSNP
rs1230775665 2439 dbSNP
rs1203376046 2443 dbSNP
rs1461998078 2446 dbSNP
rs897002073 2447 dbSNP
rs1202219551 2449 dbSNP
rs1046213991 2452 dbSNP
rs1013466596 2453 dbSNP
rs1487054625 2461 dbSNP
rs1203891566 2465 dbSNP
rs1261710708 2470 dbSNP
rs895043263 2473 dbSNP
rs1225504783 2474 dbSNP
rs1371284812 2476 dbSNP
rs1279128553 2480 dbSNP
rs367639515 2483 dbSNP
rs1449015646 2484 dbSNP
rs1385344316 2486 dbSNP
rs1309216852 2487 dbSNP
rs943838456 2488 dbSNP
rs1405199710 2489 dbSNP
rs1054722125 2491 dbSNP
rs1159782538 2491 dbSNP
rs936306577 2494 dbSNP
rs1406727244 2496 dbSNP
rs888283328 2497 dbSNP
rs924963469 2500 dbSNP
rs1048664046 2501 dbSNP
rs1042555474 2502 dbSNP
rs74250910 2503 dbSNP
rs57723579 2504 dbSNP
rs111402414 2505 dbSNP
rs1490063082 2506 dbSNP
rs1491221400 2506 dbSNP
rs368874448 2506 dbSNP
rs140483957 2509 dbSNP
rs8059577 2512 dbSNP
rs1161595759 2513 dbSNP
rs562436567 2523 dbSNP
rs1218576819 2526 dbSNP
rs1315723121 2529 dbSNP
rs943606186 2532 dbSNP
rs1283644885 2536 dbSNP
rs548431408 2537 dbSNP
rs949368216 2545 dbSNP
rs1383993629 2546 dbSNP
rs913940620 2548 dbSNP
rs2650397 2550 dbSNP
rs988242649 2552 dbSNP
rs958325626 2553 dbSNP
rs1303823785 2555 dbSNP
rs1252589553 2578 dbSNP
rs1313216234 2582 dbSNP
rs1194884808 2586 dbSNP
rs1450135410 2589 dbSNP
rs1381773065 2591 dbSNP
rs985034609 2595 dbSNP
rs1032438277 2596 dbSNP
rs986676391 2597 dbSNP
rs952065881 2608 dbSNP
rs1026294432 2612 dbSNP
rs972584646 2616 dbSNP
rs971475491 2617 dbSNP
rs997797937 2624 dbSNP
rs143143807 2625 dbSNP
rs1013332810 2626 dbSNP
rs1161292206 2629 dbSNP
rs1331011308 2631 dbSNP
rs895074374 2635 dbSNP
rs562769718 2636 dbSNP
rs1454964779 2637 dbSNP
rs1313523152 2638 dbSNP
rs1188728587 2639 dbSNP
rs2641801 2643 dbSNP
rs888158863 2644 dbSNP
rs903546943 2645 dbSNP
rs1462469171 2649 dbSNP
rs753713767 2650 dbSNP
rs1242332525 2655 dbSNP
rs1223252120 2660 dbSNP
rs937820895 2665 dbSNP
rs1421735138 2671 dbSNP
rs1426876409 2685 dbSNP
rs1170215457 2688 dbSNP
rs532511344 2689 dbSNP
rs1490869514 2692 dbSNP
rs1471098852 2694 dbSNP
rs1358957700 2697 dbSNP
rs1432020804 2698 dbSNP
rs1291211567 2699 dbSNP
rs111792657 2701 dbSNP
rs1491173175 2701 dbSNP
rs1289776374 2702 dbSNP
rs1491281334 2702 dbSNP
rs1325195265 2704 dbSNP
rs1042027385 2714 dbSNP
rs1308358160 2715 dbSNP
rs945138538 2717 dbSNP
rs901556305 2727 dbSNP
rs1216146371 2728 dbSNP
rs1484918220 2729 dbSNP
rs1040573894 2732 dbSNP
rs1481510788 2734 dbSNP
rs199847774 2737 dbSNP
rs59271210 2738 dbSNP
rs943553535 2742 dbSNP
rs910722790 2746 dbSNP
rs186903747 2747 dbSNP
rs1366915054 2753 dbSNP
rs1343988972 2755 dbSNP
rs1300810933 2762 dbSNP
rs1346863587 2763 dbSNP
rs913823908 2771 dbSNP
rs930895399 2773 dbSNP
rs1273940969 2776 dbSNP
rs1373762688 2780 dbSNP
rs919262965 2790 dbSNP
rs1352838122 2795 dbSNP
rs540928571 2796 dbSNP
rs575129429 2801 dbSNP
rs140942069 2804 dbSNP
rs1419375978 2805 dbSNP
rs1246391964 2811 dbSNP
rs544003852 2814 dbSNP
rs575320907 2816 dbSNP
rs986238251 2818 dbSNP
rs991525185 2820 dbSNP
rs953513382 2821 dbSNP
rs1481425022 2822 dbSNP
rs1366878493 2825 dbSNP
rs142290287 2826 dbSNP
rs1322437045 2827 dbSNP
rs1335943941 2831 dbSNP
rs2641802 2832 dbSNP
rs1030540470 2835 dbSNP
rs959236334 2836 dbSNP
rs1221926131 2837 dbSNP
rs914477451 2842 dbSNP
rs1253325220 2847 dbSNP
rs988492921 2848 dbSNP
rs1305559560 2853 dbSNP
rs955742608 2854 dbSNP
rs34494540 2855 dbSNP
rs376729494 2855 dbSNP
rs1033462033 2857 dbSNP
rs1280772866 2859 dbSNP
rs546046600 2860 dbSNP
rs1015184507 2861 dbSNP
rs1004257717 2862 dbSNP
rs1184729339 2868 dbSNP
rs1385782143 2870 dbSNP
rs1162077034 2873 dbSNP
rs1239595455 2873 dbSNP
rs1244001229 2873 dbSNP
rs1396614730 2873 dbSNP
rs1411231794 2873 dbSNP
rs1443362533 2873 dbSNP
rs35767878 2873 dbSNP
rs574569710 2873 dbSNP
rs71380749 2873 dbSNP
rs1340159445 2874 dbSNP
rs1491300111 2874 dbSNP
rs1216535615 2875 dbSNP
rs1256454969 2877 dbSNP
rs1457575585 2885 dbSNP
rs558333086 2886 dbSNP
rs1204668336 2896 dbSNP
rs952429610 2902 dbSNP
rs1396708027 2904 dbSNP
rs1187471043 2905 dbSNP
rs1299556642 2909 dbSNP
rs1476139366 2910 dbSNP
rs1027131542 2916 dbSNP
rs1460725108 2918 dbSNP
rs538255196 2919 dbSNP
rs117593559 2921 dbSNP
rs540491308 2930 dbSNP
rs1403650601 2933 dbSNP
rs1177672091 2937 dbSNP
rs1395317447 2941 dbSNP
rs903746015 2954 dbSNP
rs1327078058 2956 dbSNP
rs1021043028 2959 dbSNP
rs1427860165 2964 dbSNP
rs1198757459 2965 dbSNP
rs1317470932 2969 dbSNP
rs552896140 2973 dbSNP
rs1265319307 2974 dbSNP
rs1252850968 2975 dbSNP
rs1343400191 2976 dbSNP
rs1175717276 2977 dbSNP
rs1263101174 2978 dbSNP
rs1448187570 2979 dbSNP
rs11861541 2980 dbSNP
rs1480526396 2995 dbSNP
rs901500892 2996 dbSNP
rs1465402969 2998 dbSNP
rs1204109219 3001 dbSNP
rs1040189182 3003 dbSNP
rs1440338084 3005 dbSNP
rs1046176406 3008 dbSNP
rs1013381728 3009 dbSNP
rs1296358591 3011 dbSNP
rs759632604 3015 dbSNP
rs892349564 3020 dbSNP
rs1052384746 3031 dbSNP
rs936652811 3036 dbSNP
rs147508123 3039 dbSNP
rs1261709658 3043 dbSNP
rs567154851 3044 dbSNP
rs943083925 3047 dbSNP
rs1215100966 3052 dbSNP
rs1261203310 3053 dbSNP
rs182253670 3057 dbSNP
rs536815933 3063 dbSNP
rs149838102 3074 dbSNP
rs1365340255 3075 dbSNP
rs1049228883 3079 dbSNP
rs1417715381 3080 dbSNP
rs552344814 3081 dbSNP
rs1389306741 3086 dbSNP
rs908096850 3092 dbSNP
rs774259119 3093 dbSNP
rs771068054 3096 dbSNP
rs1337764546 3098 dbSNP
rs1425431257 3100 dbSNP
rs1305149998 3101 dbSNP
rs1471186822 3102 dbSNP
rs370677083 3103 dbSNP
rs1404495216 3107 dbSNP
rs952467994 3113 dbSNP
rs749414641 3120 dbSNP
rs1309249037 3122 dbSNP
rs1359499426 3126 dbSNP
rs1036779139 3134 dbSNP
rs566865072 3144 dbSNP
rs189556890 3147 dbSNP
rs1001829148 3152 dbSNP
rs377397624 3162 dbSNP
rs1252404341 3164 dbSNP
rs773428141 3169 dbSNP
rs577824176 3176 dbSNP
rs1385827319 3178 dbSNP
rs1446400311 3184 dbSNP
rs1166938642 3188 dbSNP
rs1366809933 3194 dbSNP
rs1457534109 3197 dbSNP
rs991556308 3199 dbSNP
rs958755313 3200 dbSNP
rs770141117 3206 dbSNP
rs1241123410 3209 dbSNP
rs368976427 3211 dbSNP
rs1331135494 3215 dbSNP
rs1199815989 3217 dbSNP
rs892325806 3223 dbSNP
rs1309880947 3224 dbSNP
rs1261965555 3225 dbSNP
rs561396648 3225 dbSNP
rs1236301623 3238 dbSNP
rs544807180 3238 dbSNP
rs375584782 3244 dbSNP
rs372983585 3253 dbSNP
rs1255097699 3254 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL-BAC
Disease MIMAT0019893
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020023. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020023
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL-BAC / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000258173.6 | 3UTR | UUGGCCCUCCUCCUCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
42 hsa-miR-371b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055410 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT065883 GDF11 growth differentiation factor 11 2 2
MIRT183507 BTG2 BTG anti-proliferation factor 2 2 2
MIRT277106 CDCA8 cell division cycle associated 8 2 2
MIRT300592 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT441361 ZNF75A zinc finger protein 75a 2 2
MIRT442692 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT443388 CHML CHM like, Rab escort protein 2 2 2
MIRT443571 EVX2 even-skipped homeobox 2 2 2
MIRT443671 FLT1 fms related tyrosine kinase 1 2 2
MIRT465524 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT492169 STAT3 signal transducer and activator of transcription 3 2 2
MIRT496992 TMEM231 transmembrane protein 231 2 2
MIRT509012 FBXO6 F-box protein 6 2 2
MIRT509766 NCAPD2 non-SMC condensin I complex subunit D2 2 2
MIRT514033 BNIP2 BCL2 interacting protein 2 2 2
MIRT524995 AFF1 AF4/FMR2 family member 1 2 10
MIRT529899 C1orf64 steroid receptor associated and regulated protein 2 2
MIRT530045 SMC1A structural maintenance of chromosomes 1A 2 2
MIRT534479 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT535065 PPP2R5D protein phosphatase 2 regulatory subunit B'delta 2 4
MIRT539151 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT540937 OIP5 Opa interacting protein 5 2 2
MIRT546360 SYNM synemin 2 2
MIRT553436 TPM3 tropomyosin 3 2 2
MIRT556278 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT564092 NSA2 NSA2, ribosome biogenesis homolog 2 2
MIRT568376 ATXN1 ataxin 1 2 2
MIRT572255 ANKRD52 ankyrin repeat domain 52 2 2
MIRT572453 TRIM10 tripartite motif containing 10 2 2
MIRT610741 NUDT16 nudix hydrolase 16 2 4
MIRT622754 PHACTR2 phosphatase and actin regulator 2 2 2
MIRT627220 ZC3H12B zinc finger CCCH-type containing 12B 2 2
MIRT629555 SPN sialophorin 2 2
MIRT640288 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT651922 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT684290 CDK9 cyclin dependent kinase 9 2 2
MIRT700230 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT702748 IGFBP3 insulin like growth factor binding protein 3 2 2
MIRT711110 TBC1D21 TBC1 domain family member 21 2 2
MIRT716402 SEPT5 septin 5 2 2
MIRT723677 CTC1 CST telomere replication complex component 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-371b Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (SW1990)
hsa-miR-371b-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (SW1990)
hsa-miR-371b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-371b-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)

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