miRTarBase - #MIRT497400


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pre-miRNA Information
pre-miRNA hsa-mir-873   
Genomic Coordinates chr9: 28888879 - 28888955
Synonyms MIRN873, hsa-mir-873, MIR873
Description Homo sapiens miR-873 stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-873-3p
Sequence 46| GGAGACUGAUGAGUUCCCGGGA |67
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs760528397 3 dbSNP
rs773403294 9 dbSNP
rs1273846238 13 dbSNP
rs1339396073 15 dbSNP
rs1247999695 18 dbSNP
rs377380148 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMEM245   
Synonyms C9orf5, CG-2, CG2
Description transmembrane protein 245
Transcript NM_032012   
Expression
Putative miRNA Targets on TMEM245
3'UTR of TMEM245
(miRNA target sites are highlighted)		 
>TMEM245|NM_032012|3'UTR
   1 TGTGGTTTCCTCTGCAGTGATTTTTCTAGGAAGTTCAAATTTGACAGCGAGTTCAGCTCAGCTGTGGCCCTCTGCCCTTC
  81 CAGCTGTGCCTAGCAAGCAAAACCCAGGAAAGAAGCAGAAGCCTCCTGGCCTTACATACAGAATGCCTGGACAAGAGAGA
 161 ACTTGCTGCGGGCTGCTTTGTATTTTAAAACACAGCTTGAGAGTTCAGAGTTGGTGGTTTGCTCACTTAACTGTTGTTAA
 241 GATGGCTTGAAAAGTTTCATTTTATACACTGGTACCCTGGCTTGAAATTTTTCCACTTTGGTTATCTATGTTACTATATT
 321 ATATATTTATAAAGTTATTTTAAGAACTCTAAACTACCTGCTGTTAAAAGAATAGATGGTGTAATTTTTTCCTGGTTTAA
 401 GAAATGTATTGTTAAACTTTTCTAAGACAGTCACTTTTCAAGGAAGAGGGCTTTCACTTTTGAGTGTGTAGTTGAGTGAG
 481 CAGGAAAAATGAATCTTCTACCCTTCTCCCACAATGTATTATACGCTCTTTAAGAAATAATAAATCATAAGTATAAGGGT
 561 GGGGTGGCTTATTTGATGTTCAGTTTTATATTATAACCCTGGGAGATACAAAGACTGAAGCTCTTCCTCCTCTTCCTTTT
 641 CTCTTCACGCTTCTTTACACTATTGCCAAATTATAAAACTTGGCTGACCACGTTGAAGTGAAATACTTATTAAGCTGCTA
 721 TGAATGGTAACAGTATGATAAAATTCATGCTGTTATTAGGTTTTCTCCTTCCAGGTGGTTGAAGTGAAAAATCTCAGGTG
 801 TAGCAATACTCTGATTTGTTAAATGTATCCGTTTCATTATTTGGAACTCTGCCAATAAGTTAGTTTTCAGCAGAATTTTG
 881 TATTTATGTAGTATTTTCCCATCTCTTAGCACAGTGCCTTGCACATGACTCTAAATGAATGCTTGTTGAATTGAATTGCA
 961 ACTTTAAAAATATCTCAGATATCACAATAACCAGCATAGTGCTTTACATTTTACAAAGTCCTTTTGCACATACTATTTCA
1041 CAAGTACATCACATCAGCTTTCATATAGCTTTATATTATTTTACATCAGTTTTACACTGATGGAGAAGCTAAGGTTCAGA
1121 AAAGTGACCAACTCAAAGTCGTAAAGTGTAGTAGGATTTGGCCTCAGATCTTTGACTCCGTTGTGTGCAGATTCTGCTGT
1201 ATTAGTGTTCCTTCTAAATATTGTATGCAGTTTTCCCAGTGTTACGAGATTGGTGTTGCTATCCATTTGTTGTGAATGAA
1281 GACTTGTCCTATAGTACATGACAGGGCTGAGAGTGGACTGTAGTTCTTAGCTGAACCCTTTCTACTGTTTAAAACAATCA
1361 TCAGGCCTATCCTCTGCTCCCAGGGGAATGTGGGAGAGAAAAGGGTTCTTGGCCAGGCTGTAGGTGGTGGCTCACATCTG
1441 TAATCCCAGCACTTTGGAAGGCTGAGGTGGGTGGATTGCTTGAGCCCAGGGATTTGAGATCAGCCTAGGCAACATGGCAA
1521 AACCCCATCTCTACAAAAAAAAAAAAAAAAAAAAAAAAATTAGCTGGGCACGGTGGTGTGGCTATAGTCTGAGCTACTCA
1601 GGAGGCTGATGTATGAGGATCACCTGAGTCCAGGAGGTCGAGGCTGCAGTGAGCCAAGATGGCGCCACTGCACTCCAGCC
1681 TGGGTGAGAGAGTGAGACACTGTCCCAAGGAAAAAAAAAAGTGTTGGGGGGTAGTTCTTAAGCGTTGAAGATTTCCTTTT
1761 TGGAAAGTATTTAAAGGTAGAAATATTAATAATTTTTCCTAAAACATCTCCCTAAGAAGTCACTGATAATTATAATTAGT
1841 TTAAATTTATTCTTACACTACTTAAGAAAAATTTCATTTAGAAAAGGCTACCATGAGATCTTTTGACTATATGGAGTAGA
1921 CTGCATACAGATCTCTTTATTTCTATTATGAATATTTTAGCGATTATAATCAGCTATTCCACTGAGTATTAGATTTGGTC
2001 ACTAAGTAACTCATGTTTTTCTTTAGTCAATCATTCATTCATTCACTAAAACATTTGTTGAGAGTTGGCTAAACTCTAGA
2081 TTCTGTGCCAGGCACTGTACAGGGTGATGGAGATCACTCATAAGAAGGCCTCTTGCTCTTAGCCAGATCATATGTAATAC
2161 TAAATTTAAATTTTTTGCATTAAAAGGCTAAAAAATCATTTGTTTTTGTTAATTATATACTGGTTGATTTATAGATGTAA
2241 TTAGCACATATTCATAAGAGACAAATATATACAATGAGTTACTATACATATACAAAGTGATTTTAGCTGTATAAAGTGAT
2321 ATTGCAAAAAACTACAGCTAATGTTTCTTGCTGGGTAATTATTAGCATAAATATCAGGTTCTTAGAGGTCTTTAAGAGAA
2401 TACTTTAGAGCTACCAAAATTAGCAGCAGTGATGTAATATCACCCTGAAATACCAGGAGCAGAGGTGCCCCAGAGTGCTT
2481 CACAGCTATGATCAGGAAACTTGACCTGCCCCATTGCTACAGCAACGGCATAAGGACTAGGAAGGTCCACTAGCTGGGGA
2561 GGTCTTGGAACCCTCCGAGCCAGAAAGAAGCATTCCAGCATGATTCCTCAGATGCAATGAGGAAGGTTTACAGAATTTTC
2641 ACAGGGCAACAGAGATCAAGTGGTATGAAAAGGTAGGAGTTTTAAGCTCAAGTCTCAAAGATAACCTACCTTTACATTCT
2721 CAGTCAGAATTTGACCCAGAAAGAGGAAGTTTCTTCAGGAACAGACCGTACGTTGATGAAGTAGAAGTCATTTCAGTAAA
2801 AACGGAGTACAGAACTTGGTCATAATATCTTGCATTTTATAGATTTATTAAAGATTAGTTTCAAGTTCACATTCGCTATT
2881 CAGTTGTAAACCGAATGGATGGGAGGGGAGAAAATACAAGCTCTCCACACAGGTATGCTCCTCTCTTTTCTGAGAGAGAA
2961 GGCATGGGATTTTCAGCATAAATTCCATGTTATGTGAGTGCTGTTTGAGTTCTGAAGTTCCTATCAATATCTGTTCCTGC
3041 AAGTGATCTCTGTAAGACCACCTTACATGCTGGTCTTAGTTATTGTTAAAATTGCAAGGTTTCTTCACACCCTCTTTGAT
3121 AAGAAGTGTTTAGCTGGCAGAGCTTTCCCTTGACTTCTGAGTCTAGTGTGGGTTGGCCCATGACAGTGGGAAGAAATCCA
3201 ACATGTTACATGGAGACCTTGTATGTAAACAAACTCTGTAGCCTTTGAAAGTGGAACTGCTTTTTACAGTTAAAGGGCTG
3281 CTAAATGGCTTGCAGATGAGATCTTCTGGCTCACCTTGATCTTCACATGAACCCATTGTGACCTATCTGGATTTCCTAGG
3361 ACCTGTAGTTTCCATTTGGGTTATATTAGTGCCTCAGGAATGTGTCACTACTGGTCAAGCAATACTCAGAAATTCAGGCT
3441 GTGAGGGGTTAGATTAGAGGAAAGTAATTTAGGTGAGCTATCCAGAGCTTTCAACCTCAGGGTTTATAGGAAAAAAAAAC
3521 AAAATACAAAAACCCTTAGGACTTCTCATACTCTAGCCCTGACCTTGCAGTCTCCTCTGAGGGGCCTCCTAAGACCCTTA
3601 AAATAATATTACAATAGGACTTTGAGTGTGCATTTCACAGTGGAAATAGCCTCTGGCTAGCATTACTTCCAAATGCTAGT
3681 TCCAGCTAAAAACAAGTACTTTTTATTAGTTTCTTGTCTTTCAACATTCTGCCATCAAAATATATTCATTTTATTAACTT
3761 ACCGATTATTGGGAACCTGCAAAAAAAAAAAAAAAAAAAAACACACATGCTGTCTGCAGCCACTGTTTGGTTATTTTTGA
3841 TAGTTTAAGAGAATTATAAATCAAGTTGTTCTGTCTACTAGAGTCAGAAATTCTGTGCTAGAATGGGACTTCTAAAATTA
3921 GGTGGTCCTGTCACTTTCTAGAGAAAGACCCAAATTCATAGGTTTAAGTGGCTTGTCTGACATACACATACAGCCAGTTA
4001 GTAACAGAATTCAGAATAGAATAGAGTTCTTTTTTTTCTGTCAGTCCGTTGTTCTACTTCTCTTTCCTTTTCTTCATGGT
4081 TGAGCAGCTTTTGGCAAAATGTGTTCCATATAGCAGTAGTTCCAAGAGATGTTAATAGATGTAAGAAAAAAAGTGTGTGT
4161 GTGTTGGGGGTGGGGGATTGCATGGTCAATTAAAATGAAGGAATGCTGAGTTTGTTTCCTTACTGTAGGACTTCTAAGAG
4241 TTTTGAACATGCTATTACACATTGTGAATTTATAAAAGGGGACAAACACTGTTTGACCTTAGACTGCACTCCCCTTCTTT
4321 ATTCCTCAGAGCATCTCAAAGGACTACAGGGTCCTTTGAGAAACATGGCCCTTGATCAAGTTTACAACTCTTTGAGAAGA
4401 CATCCCTAATGGAAATACTGAATGGCAGATCTATTACTGTGGTACCATGTAGTGTGTAATAAATCTTGAAGTCCAGAAAG
4481 CAAGTATATTTGCTGTTTAGAGCTATACTTAAGGTATAGAGATTCTTTTCCACCTGTGGTGTGTAAAATCAGTATTGTGT
4561 TTAATTTTGCAGGTTTTTCAAGGATCAACTAATGTGCAAATACAGTGGTGATATATTGATATTACATTTTAATAATGCTT
4641 TTGTATGGCACTTTATAGTTTTCAGACACCTTTTGTAACAGCCCTGTGAGACAGACAATATTATCCTTATTGTACAGATG
4721 GGGGGGCTCTGGAGGCTCTGAAAAGTTTTTGGTGATATTCCCCTAAGTTTATACCACAAAATGATGGAGCCAGAATTTAG
4801 TTGCAGAACTTCTGACTCCAAGTCCAGAGTTCTTTACTAGACATCTGGTTTCTTACTAGCTTTTTGCTAGCTTTTTATTT
4881 TACAGTGAAAAGTATGGAAGCAAATCCTGATAATTTTGGCTTATTATCAAATATCATTTATTTTTTATTGCAGAGACCCA
4961 GCAGATGTAACTCTCATTGTAGCCATCCCAAAGAAAACCCTTCTTTGCCCTTTGCAGTGCCACTTATTTAGGTAACTGAA
5041 GTGTATTTCCAGTACAATTTGATTTTGAACTAAGATTTGATATAGAGTTGTAATTGCTTACATAACTCTTTGAAAATGTA
5121 TCATCCCTGGGTTCTCAGGTGAAGGAGGCAATTCAAAAGTAAAAAAGAATATTCGAATACAATAAATACCCTCTGTTCTC
5201 ACACAAATGCTGTTTCTTAGCTAACTTGCTTTGACAACCTACTGATGTAACTTCTTTATTAATGTGAAATATTTATATTT
5281 TGAAATAAAATTACTAGTGTTGAATGAATCATGTGGTAAACTTAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGGCCCUUGAGUAGUCAGAGg 5'
            ||  || ||:: ||||||| 
Target 5' agCCCTGACCTTG-CAGTCTCc 3'
 3555 - 3575 155.00 -19.90
2 
miRNA  3' agggcccUUGAGUAGUCAGAGg 5'
                 |:||||  |||||| 
Target 5' agttttaAGCTCA--AGTCTCa 3'
 2678 - 2697 130.00 -13.10
3 
miRNA  3' agggcccuuGAGUAGUCAGAGg 5'
                   :|:||:|||:|| 
Target 5' caagtacttTTTATTAGTTTCt 3'
 3693 - 3714 125.00 -10.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30168412 49 COSMIC
COSN30491978 49 COSMIC
COSN30681190 62 COSMIC
COSN15316028 70 COSMIC
COSN30118287 123 COSMIC
COSN23688503 126 COSMIC
COSN26999002 126 COSMIC
COSN31573387 159 COSMIC
COSN30139235 177 COSMIC
COSN1371654 287 COSMIC
COSN19082410 315 COSMIC
COSN23475168 435 COSMIC
COSN20847843 442 COSMIC
COSN2459074 462 COSMIC
COSN6375298 527 COSMIC
COSN31487181 832 COSMIC
COSN5695122 838 COSMIC
COSN17652785 1023 COSMIC
COSN23713166 1491 COSMIC
COSN9694838 1658 COSMIC
COSN5241251 1808 COSMIC
COSN8293268 2030 COSMIC
COSN9694837 2291 COSMIC
COSN8293267 2533 COSMIC
COSN23511107 3231 COSMIC
COSN20106455 3510 COSMIC
COSN9275284 3572 COSMIC
COSN27132762 3607 COSMIC
COSN2305077 3818 COSMIC
COSN9694836 4180 COSMIC
COSN2305075 4234 COSMIC
COSN31592874 4290 COSMIC
COSN27479315 4349 COSMIC
COSN32063472 4387 COSMIC
COSN28718628 4399 COSMIC
COSN21435013 4476 COSMIC
COSN31528726 4618 COSMIC
COSN8519780 4688 COSMIC
COSN31487679 4719 COSMIC
COSN28202082 4775 COSMIC
COSN26640066 4791 COSMIC
COSN31583265 4931 COSMIC
COSN31567647 5074 COSMIC
COSN20106451 5218 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1365074172 1 dbSNP
rs1288587104 5 dbSNP
rs748329530 9 dbSNP
rs774889802 17 dbSNP
rs771719970 22 dbSNP
rs1460984351 27 dbSNP
rs1424497653 31 dbSNP
rs1172928354 32 dbSNP
rs1476928265 33 dbSNP
rs374974089 38 dbSNP
rs1191500039 40 dbSNP
rs1419306357 43 dbSNP
rs1489366859 46 dbSNP
rs779404324 48 dbSNP
rs116143242 49 dbSNP
rs372879625 56 dbSNP
rs1259363525 57 dbSNP
rs1216259562 59 dbSNP
rs778283867 61 dbSNP
rs1261010464 63 dbSNP
rs756602912 64 dbSNP
rs752782390 68 dbSNP
rs1370264819 69 dbSNP
rs10816767 70 dbSNP
rs755172628 72 dbSNP
rs751840161 74 dbSNP
rs1467650696 75 dbSNP
rs1333407260 76 dbSNP
rs771788193 77 dbSNP
rs761534512 80 dbSNP
rs1177099839 86 dbSNP
rs1357611857 87 dbSNP
rs1455722600 91 dbSNP
rs1289842463 116 dbSNP
rs774283809 121 dbSNP
rs1001702956 122 dbSNP
rs1388311779 123 dbSNP
rs1422868996 126 dbSNP
rs776428087 130 dbSNP
rs906136867 132 dbSNP
rs545982860 136 dbSNP
rs760565418 139 dbSNP
rs775040453 140 dbSNP
rs1433531447 148 dbSNP
rs1045965278 149 dbSNP
rs942122598 161 dbSNP
rs1239406968 169 dbSNP
rs887763575 170 dbSNP
rs532943631 171 dbSNP
rs949093530 172 dbSNP
rs932240349 183 dbSNP
rs7776 209 dbSNP
rs1245186790 214 dbSNP
rs1339630337 216 dbSNP
rs1052145555 222 dbSNP
rs1215551179 224 dbSNP
rs1253547715 236 dbSNP
rs1468996060 241 dbSNP
rs1423093692 242 dbSNP
rs1421142640 244 dbSNP
rs1333805499 245 dbSNP
rs560464422 254 dbSNP
rs935040049 268 dbSNP
rs778628556 274 dbSNP
rs976244413 276 dbSNP
rs556802290 280 dbSNP
rs935517571 287 dbSNP
rs1328596563 289 dbSNP
rs924112671 308 dbSNP
rs1435186238 314 dbSNP
rs925030054 315 dbSNP
rs1298828487 316 dbSNP
rs754919220 318 dbSNP
rs1224008516 322 dbSNP
rs979266913 326 dbSNP
rs1383391690 333 dbSNP
rs977128109 334 dbSNP
rs542131859 345 dbSNP
rs968890094 351 dbSNP
rs764376583 358 dbSNP
rs1265266828 363 dbSNP
rs1273789853 370 dbSNP
rs1450988480 373 dbSNP
rs1021261218 379 dbSNP
rs991591518 383 dbSNP
rs1368222639 394 dbSNP
rs868562983 398 dbSNP
rs541117494 402 dbSNP
rs1251353331 422 dbSNP
rs1002753574 424 dbSNP
rs1167517200 428 dbSNP
rs1418963718 435 dbSNP
rs961815142 441 dbSNP
rs1478590149 465 dbSNP
rs911152646 468 dbSNP
rs1014729488 470 dbSNP
rs1355836031 475 dbSNP
rs986712444 477 dbSNP
rs1307073237 478 dbSNP
rs1215179600 479 dbSNP
rs1348218028 479 dbSNP
rs781289186 486 dbSNP
rs1416192856 487 dbSNP
rs1025615465 489 dbSNP
rs1487285547 492 dbSNP
rs1293715216 498 dbSNP
rs972727271 500 dbSNP
rs1226549534 503 dbSNP
rs1292001928 512 dbSNP
rs1210327422 521 dbSNP
rs1309407536 522 dbSNP
rs556089513 524 dbSNP
rs1482207813 525 dbSNP
rs1017017165 527 dbSNP
rs1472668390 528 dbSNP
rs751769767 539 dbSNP
rs996621509 545 dbSNP
rs1342538853 553 dbSNP
rs906009926 561 dbSNP
rs1410092448 563 dbSNP
rs1167441719 565 dbSNP
rs1278956142 568 dbSNP
rs1024993584 573 dbSNP
rs1339713690 574 dbSNP
rs1271897621 577 dbSNP
rs1445536060 577 dbSNP
rs1399431855 588 dbSNP
rs111785105 593 dbSNP
rs924081380 597 dbSNP
rs1340053735 604 dbSNP
rs576483402 607 dbSNP
rs1213366655 609 dbSNP
rs1326154219 610 dbSNP
rs1406453805 611 dbSNP
rs558238558 621 dbSNP
rs1163152648 627 dbSNP
rs1466865398 632 dbSNP
rs1052086873 643 dbSNP
rs147740431 648 dbSNP
rs566751621 653 dbSNP
rs1401012623 654 dbSNP
rs1412593810 659 dbSNP
rs145695797 662 dbSNP
rs1474164135 663 dbSNP
rs1345520940 666 dbSNP
rs1295236437 667 dbSNP
rs1043462933 669 dbSNP
rs1363201954 685 dbSNP
rs1247945517 689 dbSNP
rs118139780 691 dbSNP
rs958581900 692 dbSNP
rs928306882 694 dbSNP
rs1450907089 696 dbSNP
rs770222370 698 dbSNP
rs868519241 710 dbSNP
rs1271046950 712 dbSNP
rs911029111 713 dbSNP
rs536917016 715 dbSNP
rs987128958 719 dbSNP
rs1208712705 730 dbSNP
rs933935743 731 dbSNP
rs1198925777 732 dbSNP
rs1376522704 735 dbSNP
rs1476853196 736 dbSNP
rs569474599 738 dbSNP
rs550907387 754 dbSNP
rs1159868596 757 dbSNP
rs58033846 765 dbSNP
rs1014698533 767 dbSNP
rs1006493335 769 dbSNP
rs1258998088 771 dbSNP
rs1456506681 772 dbSNP
rs918500469 773 dbSNP
rs952163034 779 dbSNP
rs1218211612 792 dbSNP
rs1396572497 793 dbSNP
rs1441491656 802 dbSNP
rs113020697 806 dbSNP
rs147468959 809 dbSNP
rs112441017 813 dbSNP
rs1330960759 815 dbSNP
rs1324335685 824 dbSNP
rs980184279 825 dbSNP
rs527458524 830 dbSNP
rs1337612223 832 dbSNP
rs1024440211 836 dbSNP
rs1266055861 843 dbSNP
rs573608207 845 dbSNP
rs1043882773 847 dbSNP
rs1426683523 852 dbSNP
rs1252051984 854 dbSNP
rs1472172216 855 dbSNP
rs1156717476 864 dbSNP
rs768103274 865 dbSNP
rs1419710001 867 dbSNP
rs1172589231 868 dbSNP
rs189172458 875 dbSNP
rs892079083 878 dbSNP
rs1180412737 880 dbSNP
rs139784686 888 dbSNP
rs999169694 889 dbSNP
rs1055912818 913 dbSNP
rs562643977 925 dbSNP
rs1237332109 933 dbSNP
rs753084907 935 dbSNP
rs937126952 938 dbSNP
rs1286875514 943 dbSNP
rs13293236 951 dbSNP
rs1246179093 953 dbSNP
rs889619589 958 dbSNP
rs3087979 961 dbSNP
rs933800309 962 dbSNP
rs1219843667 965 dbSNP
rs1197013921 970 dbSNP
rs1274671962 973 dbSNP
rs1482544786 978 dbSNP
rs1344951828 979 dbSNP
rs770629067 982 dbSNP
rs1259372683 998 dbSNP
rs1424164476 1004 dbSNP
rs765856723 1007 dbSNP
rs941357294 1023 dbSNP
rs558209525 1026 dbSNP
rs1366611309 1030 dbSNP
rs909852194 1031 dbSNP
rs1170588846 1035 dbSNP
rs980597777 1040 dbSNP
rs1437204223 1043 dbSNP
rs78345702 1047 dbSNP
rs74928846 1049 dbSNP
rs1396966343 1063 dbSNP
rs141269884 1065 dbSNP
rs536451076 1083 dbSNP
rs1028826105 1101 dbSNP
rs748668244 1104 dbSNP
rs1413464334 1114 dbSNP
rs1297701769 1117 dbSNP
rs975208120 1119 dbSNP
rs1392684316 1120 dbSNP
rs966129836 1123 dbSNP
rs1160449386 1125 dbSNP
rs1018942334 1126 dbSNP
rs1483476588 1127 dbSNP
rs1199641709 1131 dbSNP
rs1440220028 1131 dbSNP
rs1253758594 1132 dbSNP
rs1430269567 1134 dbSNP
rs1189054953 1136 dbSNP
rs1031900822 1140 dbSNP
rs569497061 1141 dbSNP
rs967694997 1146 dbSNP
rs1361092466 1151 dbSNP
rs557412877 1152 dbSNP
rs1479797822 1158 dbSNP
rs1239381580 1169 dbSNP
rs138700809 1179 dbSNP
rs1011160611 1180 dbSNP
rs1321794644 1187 dbSNP
rs878959076 1189 dbSNP
rs1278268703 1191 dbSNP
rs73527223 1207 dbSNP
rs1363916812 1213 dbSNP
rs889573135 1222 dbSNP
rs1051269787 1228 dbSNP
rs998037127 1233 dbSNP
rs1219452403 1236 dbSNP
rs1354970256 1237 dbSNP
rs1306778968 1240 dbSNP
rs1044905 1245 dbSNP
rs1381772442 1250 dbSNP
rs1284469898 1257 dbSNP
rs1486690871 1261 dbSNP
rs1055312157 1277 dbSNP
rs1247335686 1281 dbSNP
rs547099308 1282 dbSNP
rs1464531126 1307 dbSNP
rs1036960717 1309 dbSNP
rs1427309184 1314 dbSNP
rs1446824006 1323 dbSNP
rs539776698 1339 dbSNP
rs909789098 1346 dbSNP
rs1160609059 1348 dbSNP
rs528558590 1350 dbSNP
rs1245375604 1355 dbSNP
rs948714847 1361 dbSNP
rs1420233156 1381 dbSNP
rs567782106 1392 dbSNP
rs1367607595 1401 dbSNP
rs917361386 1404 dbSNP
rs768363107 1420 dbSNP
rs1045373607 1431 dbSNP
rs1228744568 1433 dbSNP
rs1267207439 1438 dbSNP
rs776331465 1442 dbSNP
rs1327038771 1444 dbSNP
rs1215416415 1447 dbSNP
rs940397052 1448 dbSNP
rs956220383 1448 dbSNP
rs749196588 1452 dbSNP
rs978984245 1454 dbSNP
rs7023890 1456 dbSNP
rs1425384795 1460 dbSNP
rs769922948 1462 dbSNP
rs985072261 1467 dbSNP
rs930593433 1469 dbSNP
rs921730554 1475 dbSNP
rs1474970444 1478 dbSNP
rs1167449813 1496 dbSNP
rs530184406 1498 dbSNP
rs974631840 1498 dbSNP
rs142711105 1504 dbSNP
rs1019079426 1506 dbSNP
rs1291470019 1507 dbSNP
rs770115607 1508 dbSNP
rs1218837379 1523 dbSNP
rs1410014837 1532 dbSNP
rs34617541 1533 dbSNP
rs868037873 1534 dbSNP
rs1230017271 1535 dbSNP
rs953819722 1535 dbSNP
rs1290505065 1536 dbSNP
rs1322450995 1539 dbSNP
rs1260708565 1556 dbSNP
rs1220905294 1559 dbSNP
rs1162129318 1560 dbSNP
rs1171180085 1560 dbSNP
rs1183079721 1560 dbSNP
rs1184180355 1560 dbSNP
rs1251557002 1560 dbSNP
rs1284106579 1560 dbSNP
rs1289618268 1560 dbSNP
rs1307012923 1560 dbSNP
rs1371797972 1560 dbSNP
rs1415116733 1560 dbSNP
rs1422777984 1560 dbSNP
rs1471807275 1560 dbSNP
rs1484175566 1560 dbSNP
rs34086900 1560 dbSNP
rs35246999 1560 dbSNP
rs398011819 1560 dbSNP
rs978079213 1567 dbSNP
rs1029427739 1569 dbSNP
rs766180447 1571 dbSNP
rs1022313323 1572 dbSNP
rs905054921 1574 dbSNP
rs1182224162 1578 dbSNP
rs1291016798 1587 dbSNP
rs10123791 1588 dbSNP
rs1232312709 1589 dbSNP
rs544209193 1592 dbSNP
rs1036908104 1594 dbSNP
rs1279574738 1597 dbSNP
rs1005383697 1610 dbSNP
rs531965378 1619 dbSNP
rs1415775505 1623 dbSNP
rs58928086 1625 dbSNP
rs1445746950 1636 dbSNP
rs1287086296 1637 dbSNP
rs1044683865 1639 dbSNP
rs1459368421 1640 dbSNP
rs948765319 1645 dbSNP
rs895774502 1657 dbSNP
rs1163728107 1661 dbSNP
rs758663571 1662 dbSNP
rs1034246899 1663 dbSNP
rs934704671 1664 dbSNP
rs752896165 1666 dbSNP
rs568430635 1682 dbSNP
rs539864443 1684 dbSNP
rs978933318 1688 dbSNP
rs112151886 1690 dbSNP
rs910824672 1692 dbSNP
rs1250417205 1693 dbSNP
rs1003707989 1694 dbSNP
rs528287602 1695 dbSNP
rs1239824842 1700 dbSNP
rs1261129391 1702 dbSNP
rs1185342676 1710 dbSNP
rs1172738051 1711 dbSNP
rs1489718719 1711 dbSNP
rs986759739 1717 dbSNP
rs1247658603 1718 dbSNP
rs1045425953 1721 dbSNP
rs1323484121 1721 dbSNP
rs138720360 1721 dbSNP
rs756922466 1722 dbSNP
rs940444557 1723 dbSNP
rs183741338 1724 dbSNP
rs1048733149 1726 dbSNP
rs953746859 1729 dbSNP
rs1275657810 1731 dbSNP
rs1029294797 1737 dbSNP
rs1222047919 1739 dbSNP
rs930541958 1743 dbSNP
rs779288362 1744 dbSNP
rs961152617 1756 dbSNP
rs34766602 1762 dbSNP
rs554379533 1763 dbSNP
rs1452816634 1783 dbSNP
rs190561744 1786 dbSNP
rs1292749088 1792 dbSNP
rs1184104234 1793 dbSNP
rs1412383273 1807 dbSNP
rs755312267 1815 dbSNP
rs754303228 1821 dbSNP
rs1388453354 1839 dbSNP
rs1368166726 1841 dbSNP
rs575797695 1843 dbSNP
rs1407124528 1844 dbSNP
rs1325001911 1845 dbSNP
rs114531063 1847 dbSNP
rs1330769718 1850 dbSNP
rs1005405259 1856 dbSNP
rs1351420699 1859 dbSNP
rs888251659 1860 dbSNP
rs1022892449 1861 dbSNP
rs911735800 1875 dbSNP
rs1357891379 1876 dbSNP
rs879804391 1882 dbSNP
rs1013214310 1887 dbSNP
rs1372587928 1892 dbSNP
rs1168326162 1893 dbSNP
rs978148146 1894 dbSNP
rs1435452870 1897 dbSNP
rs1268606915 1899 dbSNP
rs895818087 1903 dbSNP
rs1057100031 1909 dbSNP
rs1473059477 1911 dbSNP
rs966797680 1912 dbSNP
rs539373025 1913 dbSNP
rs989520516 1933 dbSNP
rs903300757 1938 dbSNP
rs1371628285 1939 dbSNP
rs1480069039 1939 dbSNP
rs959889019 1945 dbSNP
rs1033971775 1947 dbSNP
rs1003760659 1948 dbSNP
rs1246113824 1950 dbSNP
rs185718293 1961 dbSNP
rs1043099103 1962 dbSNP
rs1004558161 1968 dbSNP
rs886216919 1981 dbSNP
rs1331717411 1984 dbSNP
rs1049185944 1988 dbSNP
rs1257967087 1996 dbSNP
rs947594371 1999 dbSNP
rs910678233 2000 dbSNP
rs78397412 2002 dbSNP
rs1395988737 2007 dbSNP
rs1296544034 2010 dbSNP
rs1467689948 2022 dbSNP
rs1186683223 2024 dbSNP
rs1384745807 2033 dbSNP
rs534869394 2033 dbSNP
rs1442849479 2044 dbSNP
rs1170755560 2045 dbSNP
rs1395732371 2046 dbSNP
rs994551380 2053 dbSNP
rs1296840731 2055 dbSNP
rs1404713360 2070 dbSNP
rs986404082 2071 dbSNP
rs1336648259 2078 dbSNP
rs757336149 2078 dbSNP
rs1133868 2079 dbSNP
rs1297633031 2083 dbSNP
rs137858607 2103 dbSNP
rs1224713263 2106 dbSNP
rs1382557830 2117 dbSNP
rs1257558457 2125 dbSNP
rs777996131 2130 dbSNP
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rs1460072082 2136 dbSNP
rs1190619187 2137 dbSNP
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rs143577884 5069 dbSNP
rs921513278 5079 dbSNP
rs576426508 5083 dbSNP
rs1347469616 5087 dbSNP
rs748381515 5093 dbSNP
rs1201240269 5096 dbSNP
rs1396693566 5097 dbSNP
rs1049619817 5102 dbSNP
rs1441029678 5108 dbSNP
rs964349997 5117 dbSNP
rs1193975057 5120 dbSNP
rs1196241712 5124 dbSNP
rs1264574744 5125 dbSNP
rs911655648 5126 dbSNP
rs1453550244 5131 dbSNP
rs1167934949 5137 dbSNP
rs987183598 5139 dbSNP
rs1466295198 5155 dbSNP
rs557740405 5161 dbSNP
rs1246382707 5166 dbSNP
rs1171614627 5167 dbSNP
rs1399549593 5167 dbSNP
rs751016091 5168 dbSNP
rs1401648611 5174 dbSNP
rs1197016093 5175 dbSNP
rs950580310 5177 dbSNP
rs1298512375 5179 dbSNP
rs781550835 5182 dbSNP
rs1026607720 5186 dbSNP
rs994674283 5191 dbSNP
rs1273727803 5192 dbSNP
rs963656035 5203 dbSNP
rs1033540563 5215 dbSNP
rs201657663 5220 dbSNP
rs16401 5224 dbSNP
rs3834892 5224 dbSNP
rs748315491 5224 dbSNP
rs1255656277 5228 dbSNP
rs922750936 5230 dbSNP
rs539451290 5234 dbSNP
rs1340612213 5237 dbSNP
rs1287124641 5239 dbSNP
rs867918735 5244 dbSNP
rs1488285536 5254 dbSNP
rs1268897709 5258 dbSNP
rs1282945302 5258 dbSNP
rs1433287047 5261 dbSNP
rs1197497753 5263 dbSNP
rs1375573580 5264 dbSNP
rs1421075577 5266 dbSNP
rs28361094 5277 dbSNP
rs370239255 5277 dbSNP
rs371846931 5277 dbSNP
rs199856655 5279 dbSNP
rs1365036125 5284 dbSNP
rs1359657394 5297 dbSNP
rs1370677292 5302 dbSNP
rs138442320 5308 dbSNP
rs1443908200 5311 dbSNP
rs545584907 5313 dbSNP
rs906515549 5318 dbSNP
rs187755520 5324 dbSNP
rs1300597430 5326 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL35
Disease MIMAT0022717
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020022. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agggcccUUGAGUAGUCAGAGg 5'
                 |:||||  |||||| 
Target 5' ----uuaAGCUCA--AGUCUCa 3'
 		1 - 16
Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020022
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL35 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000374586.3 | 3UTR | UUAAGCUCAAGUCUCAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
108 hsa-miR-873-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081178 MIDN midnolin 2 4
MIRT109809 ZFX zinc finger protein, X-linked 2 4
MIRT242383 TMC5 transmembrane channel like 5 2 4
MIRT444003 METRN meteorin, glial cell differentiation regulator 2 4
MIRT444097 SEPHS1 selenophosphate synthetase 1 2 2
MIRT446158 RPL12 ribosomal protein L12 2 2
MIRT446859 SAMD9L sterile alpha motif domain containing 9 like 2 2
MIRT447275 FZD5 frizzled class receptor 5 2 2
MIRT447391 TMPRSS15 transmembrane protease, serine 15 2 2
MIRT448817 FKBP1A FK506 binding protein 1A 2 4
MIRT450582 HIST1H2BG histone cluster 1 H2B family member g 2 2
MIRT451776 USP36 ubiquitin specific peptidase 36 2 2
MIRT457961 ABCC5 ATP binding cassette subfamily C member 5 2 4
MIRT458424 KLHL38 kelch like family member 38 2 4
MIRT461383 SLFN12L schlafen family member 12 like 2 2
MIRT467793 SLC2A14 solute carrier family 2 member 14 2 2
MIRT476517 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT480290 C7orf73 short transmembrane mitochondrial protein 1 2 4
MIRT482745 HES7 hes family bHLH transcription factor 7 2 10
MIRT483189 HIST1H2AH histone cluster 1 H2A family member h 2 6
MIRT486545 DCTN4 dynactin subunit 4 2 2
MIRT486581 ZNF619 zinc finger protein 619 2 2
MIRT492604 POLR3E RNA polymerase III subunit E 2 2
MIRT494130 DCAF7 DDB1 and CUL4 associated factor 7 2 6
MIRT496023 ZBED3 zinc finger BED-type containing 3 2 2
MIRT497121 NBEAL1 neurobeachin like 1 2 2
MIRT497400 TMEM245 transmembrane protein 245 2 2
MIRT501410 RANBP10 RAN binding protein 10 2 2
MIRT510947 PPTC7 PTC7 protein phosphatase homolog 2 6
MIRT512494 ARID2 AT-rich interaction domain 2 2 2
MIRT512595 ZNF783 zinc finger family member 783 2 2
MIRT512612 CNTN4 contactin 4 2 2
MIRT517808 UGDH UDP-glucose 6-dehydrogenase 2 6
MIRT520686 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT526179 HEPH hephaestin 2 2
MIRT532568 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT533979 TADA2A transcriptional adaptor 2A 2 2
MIRT538622 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539703 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT539806 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT540422 FAM83F family with sequence similarity 83 member F 2 2
MIRT540506 CXCL10 C-X-C motif chemokine ligand 10 2 2
MIRT540619 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT542423 ZNF331 zinc finger protein 331 2 2
MIRT542454 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT543383 CC2D2A coiled-coil and C2 domain containing 2A 2 2
MIRT544777 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT544923 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit 2 2
MIRT549768 ZNF611 zinc finger protein 611 2 4
MIRT551242 COLEC10 collectin subfamily member 10 2 2
MIRT560474 ENSA endosulfine alpha 2 2
MIRT569738 GPR173 G protein-coupled receptor 173 2 2
MIRT571297 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 2 2
MIRT572345 CKAP2L cytoskeleton associated protein 2 like 2 2
MIRT573112 ERBB2IP erbb2 interacting protein 2 2
MIRT607744 ANGPT4 angiopoietin 4 2 2
MIRT607903 SPRYD4 SPRY domain containing 4 2 2
MIRT611744 SERPING1 serpin family G member 1 2 4
MIRT615101 BNC2 basonuclin 2 2 2
MIRT619124 CD40LG CD40 ligand 2 2
MIRT625572 ANKRD42 ankyrin repeat domain 42 2 2
MIRT629038 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT633986 SLC35E2 solute carrier family 35 member E2 2 2
MIRT635675 COX18 COX18, cytochrome c oxidase assembly factor 2 4
MIRT637471 DEFB105B defensin beta 105B 2 4
MIRT637503 DEFB105A defensin beta 105A 2 4
MIRT639735 MAP2K2 mitogen-activated protein kinase kinase 2 2 2
MIRT640730 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT645364 C9orf47 chromosome 9 open reading frame 47 2 2
MIRT647938 RNF152 ring finger protein 152 2 2
MIRT649400 SH2D4A SH2 domain containing 4A 2 2
MIRT656860 KIN Kin17 DNA and RNA binding protein 2 2
MIRT663470 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT663507 NKAPL NFKB activating protein like 2 4
MIRT667690 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT677403 PCNP PEST proteolytic signal containing nuclear protein 2 2
MIRT678682 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT678789 NUPL2 nucleoporin like 2 2 2
MIRT680649 KIAA1456 KIAA1456 2 2
MIRT682450 MTX3 metaxin 3 2 2
MIRT682740 CA6 carbonic anhydrase 6 2 2
MIRT684421 TUFT1 tuftelin 1 2 2
MIRT690535 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT690595 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT690771 PLA2G2C phospholipase A2 group IIC 2 2
MIRT692233 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT693667 MXRA7 matrix remodeling associated 7 2 2
MIRT695551 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT695870 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT696214 LYZ lysozyme 2 2
MIRT698368 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT700795 PHTF2 putative homeodomain transcription factor 2 2 2
MIRT701640 MYLK3 myosin light chain kinase 3 2 2
MIRT702989 HERPUD2 HERPUD family member 2 2 2
MIRT703627 FBXL3 F-box and leucine rich repeat protein 3 2 2
MIRT703783 FAM102B family with sequence similarity 102 member B 2 2
MIRT704293 DDX19B DEAD-box helicase 19B 2 2
MIRT704828 CDC73 cell division cycle 73 2 2
MIRT705014 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT708480 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT710770 PHF7 PHD finger protein 7 2 2
MIRT718918 TRIM66 tripartite motif containing 66 2 2
MIRT720390 ZNF549 zinc finger protein 549 2 2
MIRT720593 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT723515 SIGLEC8 sialic acid binding Ig like lectin 8 2 2
MIRT724458 PRKX protein kinase, X-linked 2 2
MIRT737267 UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 3 0
MIRT737356 ZIC2 Zic family member 2 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-873 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-873 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-873 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-873 Cisplatin 5460033 NSC119875 approved resistant cell line (OE19)
hsa-mir-873 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-873 Decitabine 451668 approved sensitive tissue (esopheageal cancer)
hsa-miR-873-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-873-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-873-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-873-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-873-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-873-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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