miRTarBase - #MIRT497626


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pre-miRNA Information
pre-miRNA hsa-mir-3136   
Genomic Coordinates chr3: 69048958 - 69049035
Description Homo sapiens miR-3136 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3136-5p
Sequence 10| CUGACUGAAUAGGUAGGGUCAUU |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1478587998 4 dbSNP
rs912074637 12 dbSNP
rs1465866748 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF576   
Synonyms -
Description zinc finger protein 576
Transcript NM_001145347   
Other Transcripts NM_024327   
Expression
Putative miRNA Targets on ZNF576
3'UTR of ZNF576
(miRNA target sites are highlighted)		 
>ZNF576|NM_001145347|3'UTR
   1 GTGCAGCTTAAGCCTCTCCACGGTGACGGGTGGCTCTGTGGCTGGTAGGACTCACCCATGATATGGGGTGCAGGAACTCT
  81 GGGGGCCCTGAAGGATTTGCTTCCCTCCCCTGGGAAGGCAGAGGGCTCTTAATAAAGAGGACCCAGAAGATTCTTATTTA
 161 GAGCTTCAGTCTTTGGAGCACACAGGGCCTTCGTGAGACAGTGAAATCAGATAATAATGAGATCTTTTGTTAAAAAAAAA
 241 AAATGGGAAGGGAGTGCGGGAGAGAAATGGTTTGTGTCTCCCTTATTCCCAGTTAAATACCTAGCTGCAGATTGTGCCAT
 321 CACCCTTCATTCTTCCCAGATGGATGCCATGGGCTATGGGAGCAAATTGCCCTGGACCTTTGCCTGAATGGGGGCAGGAA
 401 AGGTGAGGTGTTGCTGGCCTGTAATGCCACCAGGTGAGTTCCAGATGTGGAGCAACTTGGGCTTTTGGGGATGGGGCAGC
 481 AAAGTTGGGAGCTGGACCCCAATTGAGTGGGGGTAGCAATTGGAGTCCTTGTGTCTCTTTTCCACCCCCTGCCATCCTCA
 561 CTTAGAGGGGCCATGGCACTAGATGGCACTAGTCCCCCGATAATTTATGTCTCGTTGAAATAATTTTGTATATCATTCTA
 641 GTCCTGAAATATTTTTTTCATATGTGTAGGTGAAATGGTATGAATAAGCTAACAGGAATAGTATCTAAAAACAGAAAACA
 721 TCCATATTAAAATGTCTAAACAGGGAGCTCTGGCTTTTGAGTGGGAATTTCCAGAGAACATAAGGGTGTGGGCAGGTGGG
 801 GGAACTCAGGCCAGAGTTGGCCTCGCTTTGTGGGGAAACTGGTTTGGAATCAAACAGAGATACCTTCTGTTTCGGGTTTT
 881 ATTTGGCCAACACTGGGAGATTTCCCATTAAGATCCTATTTTCAGCTCTCTTGAAAGGCCCAACCTAGGCTGACATTGTC
 961 AGCAGGGGCAGGACAGAAGTTACAACAGGCTGGAGGGAGCAGTGGGTGTCACCCTCAACTGGAGATGAGTCCCACCAGGC
1041 CAGTTTTACCCCCTTAGTTACCTGCCCTGCACCTGCAGACAATGGTCGATGCCTTGCATATAATACTTATAGACTCTGTT
1121 TATGTTGAGGGATGTTTTTAAAGCCCACAGGTGAGGTGGATGTGGTAGACTGATCAC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuaCU-GGGAUGGAU----AAGUCAGuc 5'
             || :|:||::||    |||||||  
Target 5' gaaGATTCTTATTTAGAGCTTCAGTCtt 3'
 146 - 173 142.00 -13.00
2 
miRNA  3' uuacUGGGAUGGAUAAGUCAGUc 5'
              ::::||||   |:|||:| 
Target 5' gccaGTTTTACCCCCTTAGTTAc 3'
 1039 - 1061 123.00 -9.30
3 
miRNA  3' uuaCUGGGAUGGAUAAGUC-AGuc 5'
             ||:||||  | ||||| ||  
Target 5' taaGATCCTA--TTTTCAGCTCtc 3'
 909 - 930 116.00 -14.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30539984 7 COSMIC
COSN30521288 23 COSMIC
COSN30542190 31 COSMIC
COSN20093610 48 COSMIC
COSN30498769 51 COSMIC
COSN30541734 91 COSMIC
COSN9850789 130 COSMIC
COSN27244191 146 COSMIC
COSN28882357 184 COSMIC
COSN32096094 196 COSMIC
COSN20115838 244 COSMIC
COSN20093611 431 COSMIC
COSN1216255 927 COSMIC
COSN22280336 1529 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs202092766 5 dbSNP
rs755278793 7 dbSNP
rs999704858 10 dbSNP
rs1395703533 14 dbSNP
rs1476442575 15 dbSNP
rs959142426 17 dbSNP
rs1292770391 18 dbSNP
rs779866461 20 dbSNP
rs200110905 22 dbSNP
rs756617351 23 dbSNP
rs201933599 28 dbSNP
rs749276993 29 dbSNP
rs757440896 30 dbSNP
rs779206057 31 dbSNP
rs746099708 38 dbSNP
rs768555611 42 dbSNP
rs1022298874 46 dbSNP
rs1049955824 47 dbSNP
rs369132386 48 dbSNP
rs1198341964 51 dbSNP
rs755611477 54 dbSNP
rs960384739 65 dbSNP
rs1434983479 68 dbSNP
rs977383565 72 dbSNP
rs1236410810 75 dbSNP
rs1166102836 83 dbSNP
rs1278761774 85 dbSNP
rs1442607968 86 dbSNP
rs1395627682 89 dbSNP
rs1023418899 90 dbSNP
rs924653279 91 dbSNP
rs1410354656 94 dbSNP
rs965413268 100 dbSNP
rs556695729 108 dbSNP
rs1404013176 123 dbSNP
rs1437143574 138 dbSNP
rs1406366740 147 dbSNP
rs112732012 167 dbSNP
rs749102131 170 dbSNP
rs1234940756 176 dbSNP
rs932495507 180 dbSNP
rs940629722 183 dbSNP
rs1257616160 193 dbSNP
rs1048267766 194 dbSNP
rs909797315 195 dbSNP
rs975971174 200 dbSNP
rs923172088 204 dbSNP
rs1224537341 206 dbSNP
rs1268951991 211 dbSNP
rs1339253704 212 dbSNP
rs1215634174 213 dbSNP
rs1277271476 214 dbSNP
rs1282211833 222 dbSNP
rs1413175930 223 dbSNP
rs939960404 225 dbSNP
rs1343478379 230 dbSNP
rs1416657523 230 dbSNP
rs112881374 232 dbSNP
rs58114847 232 dbSNP
rs796438870 232 dbSNP
rs1049757528 233 dbSNP
rs59397990 245 dbSNP
rs1036682406 246 dbSNP
rs1484633521 253 dbSNP
rs1269803624 255 dbSNP
rs73556563 258 dbSNP
rs528279529 259 dbSNP
rs1055303664 260 dbSNP
rs894605465 261 dbSNP
rs1271055505 262 dbSNP
rs1013511200 265 dbSNP
rs1475729631 267 dbSNP
rs1170398248 277 dbSNP
rs774284230 279 dbSNP
rs1383221800 282 dbSNP
rs1334486153 283 dbSNP
rs1294179658 286 dbSNP
rs999631189 289 dbSNP
rs1035262987 293 dbSNP
rs896733107 304 dbSNP
rs1392366073 311 dbSNP
rs1432125041 319 dbSNP
rs1347412090 323 dbSNP
rs1011907320 335 dbSNP
rs1380055785 337 dbSNP
rs1021826182 338 dbSNP
rs761273174 342 dbSNP
rs1461282186 351 dbSNP
rs1317066698 352 dbSNP
rs374514333 353 dbSNP
rs1166713259 354 dbSNP
rs1426361267 356 dbSNP
rs771592362 362 dbSNP
rs1186537755 367 dbSNP
rs1476366486 374 dbSNP
rs2240933 375 dbSNP
rs1300365279 380 dbSNP
rs1468788462 383 dbSNP
rs1014776222 384 dbSNP
rs1224145454 387 dbSNP
rs961902375 389 dbSNP
rs1294968676 393 dbSNP
rs1357763249 395 dbSNP
rs975907199 422 dbSNP
rs562231200 431 dbSNP
rs1372263675 436 dbSNP
rs1292820096 439 dbSNP
rs1358789513 447 dbSNP
rs1460164931 453 dbSNP
rs1203594052 454 dbSNP
rs530886347 457 dbSNP
rs1447649474 469 dbSNP
rs965362990 483 dbSNP
rs1190436631 485 dbSNP
rs550995454 488 dbSNP
rs931849931 493 dbSNP
rs1028828337 499 dbSNP
rs1192999113 503 dbSNP
rs985487004 504 dbSNP
rs1443801791 510 dbSNP
rs953868371 511 dbSNP
rs946840850 512 dbSNP
rs984359251 514 dbSNP
rs1205459546 516 dbSNP
rs1344480938 521 dbSNP
rs1451235666 522 dbSNP
rs1044223275 525 dbSNP
rs1157616619 526 dbSNP
rs1303893339 528 dbSNP
rs1389992328 529 dbSNP
rs924036064 544 dbSNP
rs1298444901 546 dbSNP
rs1385061414 547 dbSNP
rs909742286 548 dbSNP
rs1436577837 550 dbSNP
rs1172403828 552 dbSNP
rs1435285897 561 dbSNP
rs939905771 566 dbSNP
rs1156795588 569 dbSNP
rs768623662 573 dbSNP
rs1418330574 575 dbSNP
rs563291522 577 dbSNP
rs772760236 580 dbSNP
rs1178062256 590 dbSNP
rs972658582 599 dbSNP
rs570756451 600 dbSNP
rs1313949072 609 dbSNP
rs191807924 610 dbSNP
rs1054850979 611 dbSNP
rs1237237202 614 dbSNP
rs894881171 615 dbSNP
rs1316760387 616 dbSNP
rs1044746767 620 dbSNP
rs946524700 621 dbSNP
rs547329550 625 dbSNP
rs1210615110 629 dbSNP
rs904726794 630 dbSNP
rs79719618 631 dbSNP
rs1031902445 634 dbSNP
rs1414907110 652 dbSNP
rs1460843869 654 dbSNP
rs536078374 656 dbSNP
rs1287102849 661 dbSNP
rs901141751 664 dbSNP
rs1015123052 671 dbSNP
rs143289457 678 dbSNP
rs1473709550 685 dbSNP
rs997356225 686 dbSNP
rs775911890 690 dbSNP
rs763244485 694 dbSNP
rs764632403 702 dbSNP
rs954252432 708 dbSNP
rs200242113 713 dbSNP
rs1486067744 722 dbSNP
rs1417018293 725 dbSNP
rs535941540 731 dbSNP
rs1203964360 739 dbSNP
rs1017150505 741 dbSNP
rs536736594 743 dbSNP
rs961220415 746 dbSNP
rs1363972532 748 dbSNP
rs953289358 769 dbSNP
rs1261693475 781 dbSNP
rs1210925081 787 dbSNP
rs374448203 798 dbSNP
rs1173684880 799 dbSNP
rs1233504656 800 dbSNP
rs927875769 801 dbSNP
rs1404694044 802 dbSNP
rs371323354 805 dbSNP
rs757359228 818 dbSNP
rs1303931251 825 dbSNP
rs986429608 826 dbSNP
rs990888252 858 dbSNP
rs1459716850 861 dbSNP
rs1393431752 862 dbSNP
rs916271523 862 dbSNP
rs867416543 875 dbSNP
rs1370279407 883 dbSNP
rs979448018 895 dbSNP
rs1428467697 901 dbSNP
rs1263092040 907 dbSNP
rs767680826 908 dbSNP
rs151285356 914 dbSNP
rs904675646 928 dbSNP
rs73556565 931 dbSNP
rs1230425107 940 dbSNP
rs1053265014 945 dbSNP
rs1357953197 952 dbSNP
rs901424613 954 dbSNP
rs545353260 966 dbSNP
rs1050179670 967 dbSNP
rs1045749893 969 dbSNP
rs888029428 970 dbSNP
rs116230528 972 dbSNP
rs1479550689 980 dbSNP
rs756353141 1001 dbSNP
rs1326263176 1004 dbSNP
rs1406189758 1006 dbSNP
rs1035991829 1007 dbSNP
rs377487192 1009 dbSNP
rs897588994 1014 dbSNP
rs1473397612 1034 dbSNP
rs1196823678 1040 dbSNP
rs1453045548 1041 dbSNP
rs572771126 1053 dbSNP
rs1428073590 1054 dbSNP
rs1194601366 1056 dbSNP
rs1453002920 1059 dbSNP
rs532284521 1062 dbSNP
rs1248030667 1079 dbSNP
rs1017035048 1090 dbSNP
rs961168806 1099 dbSNP
rs953216821 1101 dbSNP
rs888586077 1102 dbSNP
rs140538463 1111 dbSNP
rs1232000697 1113 dbSNP
rs1361355557 1117 dbSNP
rs1460815992 1119 dbSNP
rs1438303822 1126 dbSNP
rs117820749 1134 dbSNP
rs968661571 1139 dbSNP
rs960593316 1163 dbSNP
rs111291192 1165 dbSNP
rs1411968762 1180 dbSNP
rs1433424398 1183 dbSNP
rs916201074 1184 dbSNP
rs1173641324 1190 dbSNP
rs1344984763 1194 dbSNP
rs967755858 1200 dbSNP
rs1231518573 1201 dbSNP
rs979551824 1203 dbSNP
rs1483142951 1204 dbSNP
rs564566520 1216 dbSNP
rs540542746 1228 dbSNP
rs1253367588 1232 dbSNP
rs1208041841 1255 dbSNP
rs1219839949 1273 dbSNP
rs956798916 1276 dbSNP
rs1281011077 1279 dbSNP
rs1220858347 1284 dbSNP
rs1348356318 1290 dbSNP
rs1278665079 1303 dbSNP
rs923701065 1311 dbSNP
rs917980202 1312 dbSNP
rs1413055041 1322 dbSNP
rs935115522 1331 dbSNP
rs1275162106 1332 dbSNP
rs1416651787 1334 dbSNP
rs1053213164 1342 dbSNP
rs1483912217 1348 dbSNP
rs749053127 1359 dbSNP
rs1472729383 1362 dbSNP
rs922803097 1365 dbSNP
rs934209623 1366 dbSNP
rs1474626010 1381 dbSNP
rs754799684 1382 dbSNP
rs1267660080 1383 dbSNP
rs1212151298 1388 dbSNP
rs980962099 1391 dbSNP
rs145816734 1397 dbSNP
rs889747054 1399 dbSNP
rs1330910217 1404 dbSNP
rs941642072 1419 dbSNP
rs1427306795 1435 dbSNP
rs546989041 1440 dbSNP
rs1354975324 1441 dbSNP
rs778773403 1444 dbSNP
rs1170339469 1446 dbSNP
rs1391236186 1451 dbSNP
rs748058009 1458 dbSNP
rs10410931 1459 dbSNP
rs370505508 1463 dbSNP
rs1161930227 1467 dbSNP
rs1034835882 1477 dbSNP
rs1318112187 1479 dbSNP
rs772778051 1485 dbSNP
rs1391267451 1493 dbSNP
rs746562121 1495 dbSNP
rs546014023 1497 dbSNP
rs1474635633 1498 dbSNP
rs1023554708 1502 dbSNP
rs932954898 1504 dbSNP
rs1413899919 1507 dbSNP
rs1183048085 1513 dbSNP
rs968083318 1516 dbSNP
rs888862374 1524 dbSNP
rs1007843469 1525 dbSNP
rs1466134640 1546 dbSNP
rs979112868 1547 dbSNP
rs1295418022 1552 dbSNP
rs1359940321 1553 dbSNP
rs1381645295 1560 dbSNP
rs1298166228 1564 dbSNP
rs1212061885 1569 dbSNP
rs549595368 1569 dbSNP
rs1021418291 1573 dbSNP
rs1290712476 1576 dbSNP
rs542223662 1581 dbSNP
rs776155645 1584 dbSNP
rs1344055547 1585 dbSNP
rs904445896 1586 dbSNP
rs1243432298 1587 dbSNP
rs1367796698 1588 dbSNP
rs1436455719 1588 dbSNP
rs956444737 1588 dbSNP
rs975817868 1589 dbSNP
rs1030977208 1590 dbSNP
rs771719939 1593 dbSNP
rs1166430280 1599 dbSNP
rs1407760009 1601 dbSNP
rs1418151174 1608 dbSNP
rs1321986890 1617 dbSNP
rs1223283416 1622 dbSNP
rs569347743 1624 dbSNP
rs922750779 1625 dbSNP
rs763333040 1627 dbSNP
rs1239919150 1629 dbSNP
rs1485255961 1631 dbSNP
rs1188489606 1635 dbSNP
rs538388807 1641 dbSNP
rs911471751 1643 dbSNP
rs556788353 1644 dbSNP
rs981357249 1668 dbSNP
rs1038363395 1672 dbSNP
rs1224025765 1673 dbSNP
rs1305902279 1681 dbSNP
rs897187217 1683 dbSNP
rs1229801927 1689 dbSNP
rs185284306 1690 dbSNP
rs371374838 1699 dbSNP
rs933008704 1700 dbSNP
rs1439566899 1701 dbSNP
rs1453078282 1712 dbSNP
rs1353419750 1715 dbSNP
rs539064824 1718 dbSNP
rs1393153376 1723 dbSNP
rs1431577322 1723 dbSNP
rs1172904766 1725 dbSNP
rs1433611717 1729 dbSNP
rs896267293 1730 dbSNP
rs1426997115 1731 dbSNP
rs762376213 1733 dbSNP
rs1367216562 1742 dbSNP
rs552527836 1753 dbSNP
rs1205905681 1758 dbSNP
rs1484058628 1770 dbSNP
rs1278872060 1771 dbSNP
rs113604124 1774 dbSNP
rs1313222010 1777 dbSNP
rs143066548 1780 dbSNP
rs1043295179 1782 dbSNP
rs1349444177 1788 dbSNP
rs1229742164 1789 dbSNP
rs1000761553 1793 dbSNP
rs1030595865 1796 dbSNP
rs1373076943 1798 dbSNP
rs956392385 1799 dbSNP
rs998625805 1800 dbSNP
rs1315825381 1804 dbSNP
rs1156605017 1811 dbSNP
rs1417588028 1813 dbSNP
rs1411555736 1814 dbSNP
rs975765803 1819 dbSNP
rs1030089996 1825 dbSNP
rs55915894 1829 dbSNP
rs985646005 1842 dbSNP
rs1255485140 1844 dbSNP
rs895727752 1861 dbSNP
rs555591443 1862 dbSNP
rs1258160741 1865 dbSNP
rs1214042523 1869 dbSNP
rs1328876759 1875 dbSNP
rs941606158 1878 dbSNP
rs974332885 1880 dbSNP
rs1288646685 1882 dbSNP
rs1229843615 1883 dbSNP
rs1013544862 1896 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL35
Disease MIMAT0015003
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020022. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020022
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL35 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000336564.4 | 3UTR | UCAAGCUUAAGAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP 0.601 0.01 0.562 0.01 16 Click to see details
STAD -0.52 0.04 -0.755 0 12 Click to see details
HNSC 0.308 0.08 0.371 0.04 22 Click to see details
CHOL 0.895 0.15 1.000 0.5 3 Click to see details
ESCA 0.806 0.2 1.000 0.5 3 Click to see details
BRCA 0.131 0.25 0.110 0.28 30 Click to see details
THCA 0.094 0.27 0.164 0.15 43 Click to see details
PAAD 0.563 0.31 0.500 0.33 3 Click to see details
PRAD -0.134 0.32 -0.020 0.47 14 Click to see details
UCEC 0.104 0.36 -0.121 0.34 14 Click to see details
LIHC -0.059 0.39 0.114 0.3 23 Click to see details
KICH 0.064 0.41 -0.077 0.4 14 Click to see details
LUSC -0.038 0.43 -0.077 0.37 22 Click to see details
KIRC -0.027 0.47 0.045 0.45 11 Click to see details
BLCA 0.085 0.47 0.500 0.33 3 Click to see details
BLCA 0.085 0.47 0.500 0.33 3 Click to see details
BLCA 0.085 0.47 0.500 0.33 3 Click to see details
BLCA 0.085 0.47 0.500 0.33 3 Click to see details
84 hsa-miR-3136-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081899 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT185493 SRP9 signal recognition particle 9 2 2
MIRT207226 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT246179 TXNIP thioredoxin interacting protein 2 4
MIRT347685 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT444157 ZNF701 zinc finger protein 701 2 2
MIRT444505 ZNF525 zinc finger protein 525 2 2
MIRT444683 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT445131 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT446184 FGF1 fibroblast growth factor 1 2 2
MIRT447946 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT449366 ANTXR2 anthrax toxin receptor 2 2 2
MIRT449774 SULF2 sulfatase 2 2 2
MIRT450096 ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2 2
MIRT450903 CADM2 cell adhesion molecule 2 2 4
MIRT455645 YARS tyrosyl-tRNA synthetase 2 2
MIRT465135 TSC22D2 TSC22 domain family member 2 2 2
MIRT476177 GOLGA8A golgin A8 family member A 2 8
MIRT483978 PANK1 pantothenate kinase 1 2 10
MIRT497016 INO80B INO80 complex subunit B 2 2
MIRT497450 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT497626 ZNF576 zinc finger protein 576 2 2
MIRT498187 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT504036 TOMM5 translocase of outer mitochondrial membrane 5 2 2
MIRT507106 GOLGA8B golgin A8 family member B 2 4
MIRT507900 CALM2 calmodulin 2 2 6
MIRT508802 MTPN myotrophin 2 6
MIRT510407 ZNF268 zinc finger protein 268 2 4
MIRT516297 F8A2 coagulation factor VIII associated 2 2 2
MIRT516323 F8A3 coagulation factor VIII associated 3 2 2
MIRT528028 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT529396 ICK intestinal cell kinase 2 2
MIRT534463 SCD stearoyl-CoA desaturase 2 4
MIRT535438 PDE4D phosphodiesterase 4D 2 2
MIRT538187 DBN1 drebrin 1 2 2
MIRT547386 MOB1A MOB kinase activator 1A 2 2
MIRT548180 FOXC1 forkhead box C1 2 2
MIRT561585 SKI SKI proto-oncogene 2 2
MIRT569449 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT573314 RFC5 replication factor C subunit 5 2 2
MIRT574762 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT575975 Fem1a feminization 1 homolog a (C. elegans) 2 5
MIRT575999 Zfp106 zinc finger protein 106 1 1
MIRT576277 Cd59a CD59a antigen 1 1
MIRT606772 KIAA0040 KIAA0040 2 5
MIRT606833 FEM1A fem-1 homolog A 2 7
MIRT608302 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT609269 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT609405 SLC25A45 solute carrier family 25 member 45 2 2
MIRT609603 TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein 2 2
MIRT610105 IL17REL interleukin 17 receptor E like 2 3
MIRT610327 SSX5 SSX family member 5 2 2
MIRT610610 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT611066 ZNF621 zinc finger protein 621 2 2
MIRT611492 ZNF440 zinc finger protein 440 2 2
MIRT611931 ZNF106 zinc finger protein 106 2 3
MIRT612239 MICALL1 MICAL like 1 2 2
MIRT612451 SMOC1 SPARC related modular calcium binding 1 2 4
MIRT612567 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 2 2
MIRT613111 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT614946 KAT6B lysine acetyltransferase 6B 2 2
MIRT615100 BNC2 basonuclin 2 2 2
MIRT616424 FAM126B family with sequence similarity 126 member B 2 2
MIRT617839 FMO4 flavin containing monooxygenase 4 2 2
MIRT618499 HSPD1 heat shock protein family D (Hsp60) member 1 2 2
MIRT619230 FBXL4 F-box and leucine rich repeat protein 4 2 2
MIRT624202 DCP2 decapping mRNA 2 2 4
MIRT630405 MTX3 metaxin 3 2 2
MIRT640327 DAAM2 dishevelled associated activator of morphogenesis 2 2 2
MIRT642779 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT654363 RBM23 RNA binding motif protein 23 2 2
MIRT654482 RANBP2 RAN binding protein 2 2 2
MIRT656336 MED28 mediator complex subunit 28 2 2
MIRT662856 UPF3A UPF3A, regulator of nonsense mediated mRNA decay 2 2
MIRT666894 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT669526 AP5M1 adaptor related protein complex 5 mu 1 subunit 2 2
MIRT671561 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT707042 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT717063 MTMR6 myotubularin related protein 6 2 2
MIRT717223 SH2D5 SH2 domain containing 5 2 2
MIRT719867 CYP4F11 cytochrome P450 family 4 subfamily F member 11 2 2
MIRT719967 RBX1 ring-box 1 2 2
MIRT723594 FKRP fukutin related protein 2 2
MIRT725081 VCPIP1 valosin containing protein interacting protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3136-5p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3136-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3136-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-3136-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-3136-5p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-3136-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-3136-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3136-5p Neoadjuvant chemotherapy resistant tissue (breast cancer)

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