miRTarBase - #MIRT497675


—
pre-miRNA Information
pre-miRNA hsa-mir-4486   
Genomic Coordinates chr11: 19575310 - 19575372
Description Homo sapiens miR-4486 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4486
Sequence 5| GCUGGGCGAGGCUGGCA |21
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs774299284 8 dbSNP
rs902172817 14 dbSNP
rs1222795726 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SYNGR1   
Synonyms -
Description synaptogyrin 1
Transcript NM_004711   
Other Transcripts NM_145731 , NM_145738   
Expression
Putative miRNA Targets on SYNGR1
3'UTR of SYNGR1
(miRNA target sites are highlighted)		 
>SYNGR1|NM_004711|3'UTR
   1 GCCACAGTGACCGCCTGCCCCCGCCCCTCCCCATCTGTCCCCTCTCTCCACACCCAGCCCCTGCTCCTGCCCAGGCTGCC
  81 CTGCCCAGCGCCTCATCAGCCTCTGCCTTGTCCCACTGAGGTCCAGGGTAGCTCGGGGCAGGGGTGGGGCAGTCCAGTGT
 161 TGGGGACTGTCTACGTATGTGCAAGTATATCCCAGGGCATGTGCCCCGCAGGGGCCTAGAGGGTGGGGGCCAGGGGTATT
 241 TGCATTCATACATTGTGTCATCAAGCATTCCTTGAGCGCCTACTGGGCATCCGGCCTGTGCTGGGCATGGGTGGTGACAT
 321 TGGCAGAAATGGCCACTGGAAAGGGGAGCGATGAGCTGTGGAGGAAGCCCTGGTGGTACCAGAGGCCAGAATGGTGGGAA
 401 AGACAGATCCAGATAATGCTGGGAAGTGTGGCTACACCGTGGCTTGGTCATAGGGTGAGTGTAAACACCCACAGGACACT
 481 GGGGGCTGTCACCCTGCTCTGGCAGTCCTGCTAAGAGTGTCAGGGCCGTCTCCATTTTATGGTTGAGGAAACTGAGGTCT
 561 AGAGAGGTCAAGATTACTTGCCCAGAATCACTCAGGCAGCTAGTGATAGAGGTGGGGCCAAGCCCAGGCTGCCCGACTGC
 641 AGACCACGTGCTCTTCCCTGGCCACCCACCTCCTACCATCCCCACGCTTGGGGCTTCCCTGCTCAGTGTTACTGTCATTC
 721 TGGGAGGCCTTGGGGCCCTCAGCCCCTTGAGACACCCTGATTCTGCTGCATGCCAAGGGCCTGTTCTGCCCCAGCTGTTC
 801 CTCCTCCCCTGGGGACAGCCCCACCTCCGGGTCCCTCCACCCACATCCCCCTGGTCCTACCCCTGGCCCTTGGCCTCCTC
 881 CAAGAGGGCTCACCCCGGGTGCTGCTCTGTGCTCTGCGTGTCCCACAGACGCTTGTTCCAGGGGGCTCCAGCAAACCCCT
 961 TCGTGGTCTCTCAAAGGACTGATCACTGTCCTTGCCTCTAGGAGGGGTCACTAAGCCCTTACCTAGGGCTGGGTGGACAA
1041 CAAGGCACAGATGAGGGTGTGACTGGCCCGAGGTCACGGTGAGTGAGTGGCAAAGCTGGCCCTGACGCCTGGGTTTCTTG
1121 GCCCCAGCTGCCCAGCAGGTGCCTCGATTCCCTGCCCTTGTGACCTCCCAGGAAACAGAACTGATCTGGGACACTATGTC
1201 ACCTCTCCTCTCATCTGGGGTCAGTCAGGGTTCGGGGGCTGCAGCAGCCAAGCGCATGAGAGGTGTTTCCTTGGCCTTCC
1281 AGAAGGCCCACTGTGGAGCCAGCCTCCCTATGGGAGGCAGAGCGGCAAGGACAGGGCTTTGGAATCAGCCAGGTCGGCTC
1361 CTGGGCTGTGGCCGTGGAGAGACACTGCCCCCAGGATGACACAGGCAAGAGCCCCTGAGGCATGGGAGGCCCAGGGAAGA
1441 CCATGGGCTGTAGGGGAGAGTGTGGCAGGTGACCCAAAGGCCCAAAGAGGGCCGTGGGGCCTGAGGAGGTCATAATCTCT
1521 TCTGAGTGGGGGCAGGTCGATTCTTGCACAAGGTGGGCTCTTCACTGAGCCATAAGGGACAGGGAGGTATGGGAGAGCGC
1601 TGGGGGCCCATCCCCCTGTCCACCCAGTGTCCACTGGCCTGTCCTTCAGGGAGCAGAGCAGAGCAGGTGGTGGACGGGCC
1681 CAGTGCTGGGTGTTTTCACCACCATCCCCCCATCCCCCATCTAAGAATCCTAAGAGGCAGGCGATCCCTCACCTGCTTAC
1761 TCACTCAGCAGTTACCCGGCCCCTGTGCTGGAGATACCAAGGGCATGGGTGGTCCCTGCTTCGATGGCCCCAAAGCTGGG
1841 CCAGAGTTAAGGGAAAGAGGAGGAAGTCCTAAGCAGAGAAGTAGCACCATTATCCCCATTTAACAGAAGGGAAACTGAGG
1921 CTCGGCAAGCATAGGCGAGTTGGCAGTGGAACACGGATCTAAACTCAGGTGTGTCCAAGTCCTCCCAAAGGACAGCAGTG
2001 ATGGAGAGGACCCCAGCCAGCTGTGTGACAGCTGGTTGTTGCTGACTTCATTTTCCAATCCGGAGAAGGGGCTCTGTCCA
2081 CAGTCCCCCGCCGCCAGGTGGCCCACATGGGACCAGCATGGGGGCAGGTTATCTGTTGGCCTGAAGAGTGAAACCTGTAC
2161 CAGGCCAAAGGTGAGGGCGTGAGTGAGGGCAGGAGTGTTTATGGCAGAGTGAAGTTCTGTGCCCACCACAAGAGGCTGTG
2241 AGATGTTCTGACCCTCACCCACTGTCCACCAAAAGCCTCTCCTGCTGATGGGCACTAGGAGACCTCAGGGTACTGCCCAT
2321 CTGTTTCTCCTCGGGTGCCAGCCAGCTGCTGGTGATCCTCAGCCGGAGGGCAGGGTACCAGGTAAGCTTAACTCCATCTT
2401 GGGTGTTTGTGACAGGCCCTGCCTGCCACCCTAGGCAGGGAAAGCTGTCAAGACTCCTGCCAGGAATGGGGGGTGCTGAG
2481 TCATCTCACGAAGAATCCCTCACTCTTCCCGGGTTCAGCCCAGAAGCCCTTCCAGGCATGATCTTCCCCATCAGGCTGGG
2561 CTCTGGCAGGGACCTGCCCAGGATGGAGATGAGAGAGGGTGAGAGATGGAGGGCGAGATTTGGATGGGACCCAGGGCTCC
2641 TGACTCTGCCCTGGAAGGTTCATGGGGAAACTCGCTCCTTCTGTTGGCAGAGGACAGCCCCTGGGGAACCCCAGGCCCAA
2721 CTCTGTCCGGTATCCCTTTTCCTCCCAGCTGCCCTCCCCTACTTCTCCCTTGCTCCCAAAGCTTTCCTTGGAGAAGGGCC
2801 CTCCTGCAGCTGGACCCTGCAGGGTGGCTCCCTCCTCCCCATCAAGCACAAGAGAGGGCCCAGGAAAAAAGGTTTCACAT
2881 AAGTGTAGAGTCGCAAGGACGCTTAGAGTCGGCAGAGTCTGGGGTAGGGAGACAGCGACTTGTCCAAGGTCAAGCACAGA
2961 GGGAGAGGTTCAGGAGTCAGGTCTTCTGCCTTCTGAGTTGGCTCATCCTGGGCAGTCACAGACTGTCCTGCCTGCACGGC
3041 TCCTATCCACCTGGGGGTGTCGCAGTTGAGGGGCTAATTCCCAGGGGACTGACGTTAGTTCCCTACTCCATCCTTCCCTG
3121 GTGATTCTTGATCTTCAAAGCCTCGGGGATCCCAGGTTTCCCCATGTAACTGAGACACCCTGCCTGTTAGCCCTGGGAGA
3201 CCCCTAACCTTGGCCCAAGACCCCTTTGATTCTCTAAGGAGCACGAAAGGGGGAATGCCCCTCCCAGGAGTTTATGGGAG
3281 AAGGGACTGGGCCGGCTGCCTCCCAGCGATGCACTTGACCTGACACTCCCCATGTCCTGGTGCGCACAGCCCTTGTCGGT
3361 GCCCCGGCCCCTCCCGCAGCGTTACTGCCTGTGTATAGTATAAATATATATATTTTCTATATATAAGATGTATAATATAA
3441 GGCTCCACAAATATATCTGTGTGTGTGTGTGCGTGTGTGTGCGGTGAAGGGCGGTCCCCATCCTGGGCCCCCACTCTAGA
3521 CCCCCCCACCACCTGGTTAAGTCTCGAGTGAATCCAGTGGCCCCGTGGCACCCTCCTTTATGACATCCATCCATCTGTGG
3601 TGAACCAAGTGAAGGTGGTGACTTCTGGTGACATAGTAATAAAGTGAAGACTCAGAACCCACCAGCGATTGCAAAAAAAA
3681 AAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acGGUCGGAGCGGGUCg 5'
            |||||  :|||||| 
Target 5' ccCCAGC--TGCCCAGc 3'
 1122 - 1136 139.00 -22.10
2 
miRNA  3' acgGUCGGAGCGGGUCg 5'
             | ||| :|||||| 
Target 5' aggCTGCCCTGCCCAGc 3'
 73 - 89 138.00 -23.60
3 
miRNA  3' acggucgGAGCGGGUCg 5'
                 ||:|||||| 
Target 5' aagattaCTTGCCCAGa 3'
 570 - 586 134.00 -16.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26997638 13 COSMIC
COSN31557679 13 COSMIC
COSN511021 16 COSMIC
COSN26997636 23 COSMIC
COSN30143036 24 COSMIC
COSN4893203 24 COSMIC
COSN26643930 26 COSMIC
COSN31556469 34 COSMIC
COSN26642326 49 COSMIC
COSN32053411 68 COSMIC
COSN26641258 76 COSMIC
COSN28802359 90 COSMIC
COSN31545963 93 COSMIC
COSN8018782 113 COSMIC
COSN1262034 306 COSMIC
COSN28943036 321 COSMIC
COSN14997383 422 COSMIC
COSN31944385 511 COSMIC
COSN20284071 531 COSMIC
COSN1899070 728 COSMIC
COSN20317980 943 COSMIC
COSN32015123 1027 COSMIC
COSN1899071 1573 COSMIC
COSN25027963 2090 COSMIC
COSN16351292 2196 COSMIC
COSN9166021 2236 COSMIC
COSN22056708 2470 COSMIC
COSN32171091 2787 COSMIC
COSN31490119 2818 COSMIC
COSN5803193 2819 COSMIC
COSN31553383 2823 COSMIC
COSN22043232 2837 COSMIC
COSN31546980 2901 COSMIC
COSN26572431 2929 COSMIC
COSN30177220 2960 COSMIC
COSN31570114 2984 COSMIC
COSN31588577 3022 COSMIC
COSN31547422 3081 COSMIC
COSN31578704 3198 COSMIC
COSN8010659 3263 COSMIC
COSN26574697 3296 COSMIC
COSN31556685 3307 COSMIC
COSN31577657 3382 COSMIC
COSN31565447 3435 COSMIC
COSN31512807 3493 COSMIC
COSN8612724 3510 COSMIC
COSN16125507 3526 COSMIC
COSN8612725 3638 COSMIC
COSN31571084 3645 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs770764115 1 dbSNP
rs778810244 7 dbSNP
rs1218148108 10 dbSNP
rs745736657 12 dbSNP
rs111520547 13 dbSNP
rs775498326 14 dbSNP
rs1327178667 17 dbSNP
rs964447730 18 dbSNP
rs1257175170 19 dbSNP
rs1409891257 22 dbSNP
rs747144169 23 dbSNP
rs768725059 24 dbSNP
rs1244923321 25 dbSNP
rs776957184 27 dbSNP
rs529511973 28 dbSNP
rs1424476056 30 dbSNP
rs1478913467 32 dbSNP
rs1168878407 34 dbSNP
rs1400025362 41 dbSNP
rs1406328273 42 dbSNP
rs925754376 43 dbSNP
rs989676491 45 dbSNP
rs1236307605 50 dbSNP
rs1210036774 59 dbSNP
rs1317988727 61 dbSNP
rs1286809839 77 dbSNP
rs774075658 84 dbSNP
rs541508242 89 dbSNP
rs112457365 90 dbSNP
rs1203977207 91 dbSNP
rs1248335777 111 dbSNP
rs73414374 116 dbSNP
rs1302268294 118 dbSNP
rs927951074 121 dbSNP
rs1346840483 122 dbSNP
rs1315994626 124 dbSNP
rs929967800 133 dbSNP
rs945641073 135 dbSNP
rs551776968 136 dbSNP
rs1327027436 140 dbSNP
rs7289425 142 dbSNP
rs928204817 143 dbSNP
rs1486498679 144 dbSNP
rs938060914 145 dbSNP
rs1232387083 157 dbSNP
rs1039537618 158 dbSNP
rs1214968432 160 dbSNP
rs1298071009 172 dbSNP
rs1308295928 174 dbSNP
rs531670457 175 dbSNP
rs549671585 176 dbSNP
rs1320078842 199 dbSNP
rs1249666999 208 dbSNP
rs899274016 209 dbSNP
rs1364054846 212 dbSNP
rs767168836 220 dbSNP
rs1399244670 222 dbSNP
rs567870025 223 dbSNP
rs1365972194 225 dbSNP
rs1304670935 229 dbSNP
rs930683656 230 dbSNP
rs1051296917 232 dbSNP
rs1429749756 233 dbSNP
rs1422342768 242 dbSNP
rs1047601979 248 dbSNP
rs1010169 249 dbSNP
rs1270062858 253 dbSNP
rs1487644840 253 dbSNP
rs1265048925 254 dbSNP
rs998939668 255 dbSNP
rs185016982 256 dbSNP
rs1009143995 261 dbSNP
rs958298812 265 dbSNP
rs1188036709 275 dbSNP
rs545286572 278 dbSNP
rs1018896069 281 dbSNP
rs1284992115 284 dbSNP
rs1427529229 286 dbSNP
rs560771314 290 dbSNP
rs1298379078 292 dbSNP
rs995879821 293 dbSNP
rs772348235 294 dbSNP
rs957132650 295 dbSNP
rs988488226 296 dbSNP
rs764182738 302 dbSNP
rs1431778478 311 dbSNP
rs1439244228 312 dbSNP
rs1187817247 314 dbSNP
rs928055268 321 dbSNP
rs951386167 334 dbSNP
rs1481709707 337 dbSNP
rs773296568 338 dbSNP
rs1362977270 341 dbSNP
rs982776903 347 dbSNP
rs1381815429 350 dbSNP
rs1293563959 351 dbSNP
rs760861644 356 dbSNP
rs909786237 361 dbSNP
rs1264904295 362 dbSNP
rs966944525 368 dbSNP
rs941322677 370 dbSNP
rs1307357088 376 dbSNP
rs565804843 378 dbSNP
rs1233839822 381 dbSNP
rs982682481 395 dbSNP
rs539041257 398 dbSNP
rs928269518 407 dbSNP
rs1010170 409 dbSNP
rs758589843 423 dbSNP
rs920557817 436 dbSNP
rs777228906 439 dbSNP
rs144484031 440 dbSNP
rs933822156 449 dbSNP
rs930716268 469 dbSNP
rs902960000 473 dbSNP
rs1047880420 481 dbSNP
rs1464927923 484 dbSNP
rs998513466 486 dbSNP
rs1160231915 489 dbSNP
rs5757650 501 dbSNP
rs375452155 502 dbSNP
rs1178163243 504 dbSNP
rs1461817664 513 dbSNP
rs1244963851 527 dbSNP
rs894054655 528 dbSNP
rs556116568 529 dbSNP
rs751679382 542 dbSNP
rs796891277 549 dbSNP
rs1246145796 553 dbSNP
rs1384373855 561 dbSNP
rs755239509 565 dbSNP
rs1394828322 567 dbSNP
rs1032648027 568 dbSNP
rs1421885488 575 dbSNP
rs781341646 578 dbSNP
rs1004130765 608 dbSNP
rs1445392091 613 dbSNP
rs574250402 619 dbSNP
rs951572881 624 dbSNP
rs541680181 629 dbSNP
rs1262300281 633 dbSNP
rs1020028261 635 dbSNP
rs971543110 636 dbSNP
rs909921947 640 dbSNP
rs1222790233 645 dbSNP
rs982328834 647 dbSNP
rs1035577011 648 dbSNP
rs959655481 649 dbSNP
rs921198894 652 dbSNP
rs1296905679 653 dbSNP
rs1292720408 654 dbSNP
rs1359029929 661 dbSNP
rs1353543278 662 dbSNP
rs933826048 669 dbSNP
rs987061770 669 dbSNP
rs1472494175 671 dbSNP
rs991028692 675 dbSNP
rs1373628916 682 dbSNP
rs1284693913 686 dbSNP
rs1316052762 687 dbSNP
rs147854258 691 dbSNP
rs1282098329 699 dbSNP
rs765698673 704 dbSNP
rs952059131 705 dbSNP
rs1287277563 729 dbSNP
rs1208787404 737 dbSNP
rs1360764520 754 dbSNP
rs202033107 762 dbSNP
rs1221017347 765 dbSNP
rs1252483852 765 dbSNP
rs1339027081 768 dbSNP
rs1054212073 769 dbSNP
rs1405896187 770 dbSNP
rs1333092460 771 dbSNP
rs892765156 777 dbSNP
rs948384471 781 dbSNP
rs1045310836 788 dbSNP
rs1472113909 790 dbSNP
rs1464031451 798 dbSNP
rs1179397461 804 dbSNP
rs905473283 806 dbSNP
rs1478879594 807 dbSNP
rs1244690739 810 dbSNP
rs1197732819 811 dbSNP
rs1437987959 811 dbSNP
rs983436524 823 dbSNP
rs1035638914 825 dbSNP
rs533511796 826 dbSNP
rs552093263 829 dbSNP
rs141080074 830 dbSNP
rs1435551685 831 dbSNP
rs1040221066 833 dbSNP
rs921727317 836 dbSNP
rs931921026 842 dbSNP
rs1357430261 848 dbSNP
rs1333495156 852 dbSNP
rs962663741 855 dbSNP
rs530815967 863 dbSNP
rs1177065724 864 dbSNP
rs1280121282 868 dbSNP
rs1372519883 875 dbSNP
rs1416036565 878 dbSNP
rs1054340058 879 dbSNP
rs1171729159 882 dbSNP
rs1305328016 885 dbSNP
rs189397079 892 dbSNP
rs748769451 897 dbSNP
rs1041348525 898 dbSNP
rs550217161 900 dbSNP
rs986643050 904 dbSNP
rs924405497 906 dbSNP
rs1276991807 908 dbSNP
rs1438985941 910 dbSNP
rs1204592382 919 dbSNP
rs906971579 925 dbSNP
rs1003001224 929 dbSNP
rs41274555 931 dbSNP
rs1480576312 932 dbSNP
rs773934783 934 dbSNP
rs1376262207 940 dbSNP
rs767248227 942 dbSNP
rs1177216946 943 dbSNP
rs914335694 945 dbSNP
rs750012475 963 dbSNP
rs759054296 964 dbSNP
rs1333306376 967 dbSNP
rs1401052381 974 dbSNP
rs1362125556 977 dbSNP
rs1044479449 980 dbSNP
rs529042096 985 dbSNP
rs1454871119 995 dbSNP
rs73885211 997 dbSNP
rs565635610 1013 dbSNP
rs1027936768 1016 dbSNP
rs1434498628 1018 dbSNP
rs1321753186 1022 dbSNP
rs1328720825 1023 dbSNP
rs1474084103 1024 dbSNP
rs1236212058 1033 dbSNP
rs939634716 1039 dbSNP
rs952254794 1042 dbSNP
rs755679720 1051 dbSNP
rs150297796 1063 dbSNP
rs887235564 1069 dbSNP
rs551198281 1070 dbSNP
rs966163098 1071 dbSNP
rs771762773 1079 dbSNP
rs369900701 1088 dbSNP
rs931851324 1092 dbSNP
rs1327704367 1094 dbSNP
rs1296051485 1101 dbSNP
rs1418746624 1103 dbSNP
rs1371376999 1106 dbSNP
rs183726836 1107 dbSNP
rs914515436 1108 dbSNP
rs556079761 1123 dbSNP
rs1028776212 1124 dbSNP
rs955409282 1126 dbSNP
rs149055502 1134 dbSNP
rs1031604238 1139 dbSNP
rs1191902425 1142 dbSNP
rs570401095 1145 dbSNP
rs535227488 1146 dbSNP
rs553643708 1147 dbSNP
rs1197222740 1151 dbSNP
rs1255295830 1167 dbSNP
rs533117900 1168 dbSNP
rs1469233344 1187 dbSNP
rs1289154230 1191 dbSNP
rs1219185628 1195 dbSNP
rs146265257 1195 dbSNP
rs370067421 1195 dbSNP
rs894211184 1196 dbSNP
rs201218391 1197 dbSNP
rs578116096 1211 dbSNP
rs1399143049 1219 dbSNP
rs979786643 1221 dbSNP
rs1294919367 1230 dbSNP
rs545436539 1234 dbSNP
rs1168590597 1235 dbSNP
rs866373972 1238 dbSNP
rs1464003791 1239 dbSNP
rs1166939900 1250 dbSNP
rs1395111041 1253 dbSNP
rs888041790 1254 dbSNP
rs5995722 1255 dbSNP
rs1014929380 1257 dbSNP
rs1327884868 1259 dbSNP
rs1477689784 1277 dbSNP
rs1430954084 1292 dbSNP
rs1193141784 1293 dbSNP
rs575560805 1294 dbSNP
rs1315456509 1297 dbSNP
rs1246222009 1300 dbSNP
rs1234575440 1311 dbSNP
rs1319980093 1324 dbSNP
rs551273856 1325 dbSNP
rs1217855646 1328 dbSNP
rs976103038 1330 dbSNP
rs898576416 1338 dbSNP
rs561627627 1343 dbSNP
rs1029522821 1349 dbSNP
rs529199832 1354 dbSNP
rs1217143206 1356 dbSNP
rs1366422981 1359 dbSNP
rs1331485697 1366 dbSNP
rs1448319004 1368 dbSNP
rs117169690 1374 dbSNP
rs989962145 1375 dbSNP
rs891095059 1378 dbSNP
rs764090819 1380 dbSNP
rs756640 1382 dbSNP
rs1424702510 1388 dbSNP
rs1179404129 1389 dbSNP
rs945966511 1396 dbSNP
rs1236363048 1403 dbSNP
rs1197954232 1407 dbSNP
rs977778504 1416 dbSNP
rs1031992790 1422 dbSNP
rs1257577425 1423 dbSNP
rs1230749239 1425 dbSNP
rs1311298716 1426 dbSNP
rs761827673 1437 dbSNP
rs1241765244 1445 dbSNP
rs1374021247 1446 dbSNP
rs533834506 1447 dbSNP
rs8136596 1448 dbSNP
rs894246426 1449 dbSNP
rs931021062 1451 dbSNP
rs928423086 1455 dbSNP
rs1190150567 1465 dbSNP
rs959945603 1467 dbSNP
rs1049266208 1476 dbSNP
rs1375142344 1477 dbSNP
rs1159478937 1481 dbSNP
rs1418539596 1482 dbSNP
rs983167531 1494 dbSNP
rs1460840873 1495 dbSNP
rs751660657 1496 dbSNP
rs908781367 1502 dbSNP
rs1161269754 1516 dbSNP
rs1198573228 1525 dbSNP
rs138393719 1528 dbSNP
rs1482800718 1537 dbSNP
rs569683458 1539 dbSNP
rs1386823770 1540 dbSNP
rs1350987451 1554 dbSNP
rs555705935 1560 dbSNP
rs920053917 1567 dbSNP
rs537018793 1570 dbSNP
rs932852439 1574 dbSNP
rs1050241177 1575 dbSNP
rs891238057 1577 dbSNP
rs1299139101 1581 dbSNP
rs762185276 1581 dbSNP
rs1008625468 1587 dbSNP
rs549043741 1592 dbSNP
rs1416129188 1599 dbSNP
rs1015626847 1600 dbSNP
rs902081477 1606 dbSNP
rs1458460139 1611 dbSNP
rs997949935 1619 dbSNP
rs567950807 1628 dbSNP
rs1244615953 1632 dbSNP
rs62228450 1633 dbSNP
rs1264086664 1638 dbSNP
rs1011468154 1640 dbSNP
rs1283104619 1646 dbSNP
rs753040426 1651 dbSNP
rs1206065250 1667 dbSNP
rs74592045 1668 dbSNP
rs969855750 1671 dbSNP
rs553392217 1676 dbSNP
rs967216607 1677 dbSNP
rs578104051 1679 dbSNP
rs778145774 1682 dbSNP
rs959840986 1690 dbSNP
rs567616807 1700 dbSNP
rs1392980845 1705 dbSNP
rs1014508477 1706 dbSNP
rs1424210254 1706 dbSNP
rs1460884737 1706 dbSNP
rs991575241 1711 dbSNP
rs188093562 1712 dbSNP
rs1476716392 1716 dbSNP
rs963017934 1718 dbSNP
rs1199148676 1722 dbSNP
rs915545771 1737 dbSNP
rs575362012 1741 dbSNP
rs1212492570 1743 dbSNP
rs1365446708 1744 dbSNP
rs1259255195 1746 dbSNP
rs1220918416 1748 dbSNP
rs757796334 1757 dbSNP
rs1316447131 1759 dbSNP
rs181329970 1761 dbSNP
rs920189434 1763 dbSNP
rs1333010920 1776 dbSNP
rs1157782204 1778 dbSNP
rs886849990 1779 dbSNP
rs1440233446 1790 dbSNP
rs1401028344 1794 dbSNP
rs186542126 1803 dbSNP
rs1436135906 1804 dbSNP
rs191015440 1810 dbSNP
rs1418555190 1811 dbSNP
rs1172909691 1813 dbSNP
rs1326414447 1814 dbSNP
rs540881435 1824 dbSNP
rs1036514990 1828 dbSNP
rs866600408 1830 dbSNP
rs559402688 1833 dbSNP
rs1192529360 1837 dbSNP
rs1457816475 1839 dbSNP
rs1239397180 1854 dbSNP
rs912633940 1862 dbSNP
rs997752587 1870 dbSNP
rs1053203884 1874 dbSNP
rs1050396933 1882 dbSNP
rs142975397 1897 dbSNP
rs1233761276 1899 dbSNP
rs1338017752 1901 dbSNP
rs796590930 1905 dbSNP
rs1444513903 1910 dbSNP
rs775321878 1912 dbSNP
rs1353828444 1914 dbSNP
rs1042966505 1915 dbSNP
rs1240292646 1916 dbSNP
rs1448668670 1917 dbSNP
rs1011522889 1920 dbSNP
rs1351797101 1924 dbSNP
rs182036462 1925 dbSNP
rs1381644695 1926 dbSNP
rs1176189988 1937 dbSNP
rs1469089338 1938 dbSNP
rs967416272 1943 dbSNP
rs537824921 1953 dbSNP
rs746689832 1954 dbSNP
rs768518828 1955 dbSNP
rs1354633958 1956 dbSNP
rs530664180 1970 dbSNP
rs991381806 1982 dbSNP
rs1222125543 1988 dbSNP
rs1372597354 1992 dbSNP
rs915828684 1999 dbSNP
rs776576695 2000 dbSNP
rs962984108 2010 dbSNP
rs1450045090 2013 dbSNP
rs973068909 2025 dbSNP
rs1311989317 2026 dbSNP
rs1419960078 2028 dbSNP
rs1362030647 2053 dbSNP
rs1027174306 2061 dbSNP
rs6001571 2062 dbSNP
rs549109086 2063 dbSNP
rs1182967297 2066 dbSNP
rs1474033086 2075 dbSNP
rs186637552 2079 dbSNP
rs1187642214 2080 dbSNP
rs986026460 2082 dbSNP
rs1488770363 2084 dbSNP
rs1265599595 2088 dbSNP
rs908317343 2090 dbSNP
rs765283721 2091 dbSNP
rs528113909 2093 dbSNP
rs1332534274 2094 dbSNP
rs1292490758 2098 dbSNP
rs62228451 2099 dbSNP
rs941639470 2105 dbSNP
rs1429523382 2107 dbSNP
rs1349984809 2108 dbSNP
rs752328934 2113 dbSNP
rs1407614785 2114 dbSNP
rs1464138866 2115 dbSNP
rs571882825 2125 dbSNP
rs1416306682 2128 dbSNP
rs1043103896 2140 dbSNP
rs1050667748 2144 dbSNP
rs539202324 2147 dbSNP
rs889350907 2149 dbSNP
rs1011554157 2153 dbSNP
rs1043013542 2155 dbSNP
rs1426148261 2156 dbSNP
rs1399329519 2158 dbSNP
rs1485635211 2162 dbSNP
rs55706518 2179 dbSNP
rs1223820998 2180 dbSNP
rs1467119565 2185 dbSNP
rs1272456271 2188 dbSNP
rs937239420 2190 dbSNP
rs998915838 2196 dbSNP
rs1035935225 2198 dbSNP
rs771067942 2203 dbSNP
rs1293117957 2217 dbSNP
rs201979732 2220 dbSNP
rs1367832808 2222 dbSNP
rs959939747 2224 dbSNP
rs1393004435 2227 dbSNP
rs1325835560 2229 dbSNP
rs1466551112 2230 dbSNP
rs867934297 2232 dbSNP
rs760782109 2235 dbSNP
rs1356659129 2239 dbSNP
rs1168721671 2242 dbSNP
rs1013157051 2250 dbSNP
rs1426106272 2259 dbSNP
rs1443403757 2264 dbSNP
rs1022917754 2265 dbSNP
rs1193046925 2270 dbSNP
rs1452654318 2273 dbSNP
rs1252379560 2284 dbSNP
rs1199219539 2287 dbSNP
rs1459004450 2288 dbSNP
rs1249446985 2298 dbSNP
rs1203532698 2301 dbSNP
rs952590476 2310 dbSNP
rs569004356 2311 dbSNP
rs908181690 2327 dbSNP
rs961429258 2333 dbSNP
rs879283688 2334 dbSNP
rs1340000705 2345 dbSNP
rs1369634466 2352 dbSNP
rs922334410 2354 dbSNP
rs1236159309 2355 dbSNP
rs1448202052 2359 dbSNP
rs1469689573 2365 dbSNP
rs191145232 2366 dbSNP
rs1266316038 2382 dbSNP
rs1360031382 2387 dbSNP
rs1050533431 2395 dbSNP
rs910821603 2404 dbSNP
rs1394589815 2414 dbSNP
rs756351994 2420 dbSNP
rs1441524442 2430 dbSNP
rs371556641 2432 dbSNP
rs1043046050 2436 dbSNP
rs1028690370 2439 dbSNP
rs953171788 2440 dbSNP
rs903144156 2460 dbSNP
rs73414378 2469 dbSNP
rs1373083329 2472 dbSNP
rs545513775 2476 dbSNP
rs1346651311 2480 dbSNP
rs989007807 2483 dbSNP
rs183310929 2489 dbSNP
rs553208529 2490 dbSNP
rs1012780268 2491 dbSNP
rs1443661367 2493 dbSNP
rs968829570 2510 dbSNP
rs1022781924 2511 dbSNP
rs186938340 2512 dbSNP
rs1362069819 2513 dbSNP
rs373473073 2530 dbSNP
rs1385241478 2533 dbSNP
rs1424278241 2538 dbSNP
rs927275913 2539 dbSNP
rs1327049555 2546 dbSNP
rs937356220 2553 dbSNP
rs1057019447 2557 dbSNP
rs1263434285 2570 dbSNP
rs917180225 2575 dbSNP
rs1005440550 2579 dbSNP
rs545176527 2587 dbSNP
rs1322817638 2594 dbSNP
rs563297917 2598 dbSNP
rs779522178 2600 dbSNP
rs1355137819 2602 dbSNP
rs1214156410 2607 dbSNP
rs376731439 2613 dbSNP
rs745337198 2615 dbSNP
rs976809101 2616 dbSNP
rs1382916510 2632 dbSNP
rs1288326632 2634 dbSNP
rs757940416 2641 dbSNP
rs1261843023 2659 dbSNP
rs1050603255 2674 dbSNP
rs888766775 2675 dbSNP
rs1162594614 2676 dbSNP
rs1474754123 2684 dbSNP
rs1422184053 2693 dbSNP
rs953904087 2696 dbSNP
rs1194896759 2699 dbSNP
rs1008995362 2703 dbSNP
rs1463424836 2710 dbSNP
rs1209890520 2716 dbSNP
rs986274415 2721 dbSNP
rs1231928517 2730 dbSNP
rs1334628396 2731 dbSNP
rs1279187973 2747 dbSNP
rs910684546 2757 dbSNP
rs947641357 2759 dbSNP
rs979021724 2767 dbSNP
rs1019852438 2769 dbSNP
rs1456605031 2774 dbSNP
rs1295004245 2777 dbSNP
rs965643144 2782 dbSNP
rs1010407286 2784 dbSNP
rs1290906819 2788 dbSNP
rs1385906325 2789 dbSNP
rs1456718964 2794 dbSNP
rs549547227 2797 dbSNP
rs1020499725 2798 dbSNP
rs745487765 2800 dbSNP
rs1460804075 2803 dbSNP
rs1400790891 2807 dbSNP
rs924855637 2813 dbSNP
rs1169390928 2824 dbSNP
rs934701842 2825 dbSNP
rs1474250790 2826 dbSNP
rs1399548662 2827 dbSNP
rs1276370136 2831 dbSNP
rs1199038743 2838 dbSNP
rs1057438220 2839 dbSNP
rs968876124 2843 dbSNP
rs895913560 2850 dbSNP
rs1160006980 2852 dbSNP
rs530728094 2855 dbSNP
rs1233750569 2867 dbSNP
rs542714908 2872 dbSNP
rs1044251226 2873 dbSNP
rs888244757 2874 dbSNP
rs554071019 2880 dbSNP
rs1197897570 2883 dbSNP
rs1217647487 2885 dbSNP
rs76437831 2889 dbSNP
rs5995725 2893 dbSNP
rs993258782 2894 dbSNP
rs41274557 2901 dbSNP
rs1476492121 2902 dbSNP
rs1377526039 2905 dbSNP
rs571905267 2907 dbSNP
rs1330713779 2908 dbSNP
rs542912322 2912 dbSNP
rs1413676518 2913 dbSNP
rs1172816342 2920 dbSNP
rs532737714 2922 dbSNP
rs5995726 2925 dbSNP
rs953801036 2934 dbSNP
rs1161728581 2935 dbSNP
rs762318054 2937 dbSNP
rs920390788 2938 dbSNP
rs1184502992 2944 dbSNP
rs1419265699 2964 dbSNP
rs1272668035 2969 dbSNP
rs1211891564 2975 dbSNP
rs1296423547 2981 dbSNP
rs1377311274 2984 dbSNP
rs1021993519 2992 dbSNP
rs189828435 2998 dbSNP
rs748031019 3003 dbSNP
rs11548412 3010 dbSNP
rs930499099 3012 dbSNP
rs776114923 3014 dbSNP
rs1334974619 3017 dbSNP
rs1334522788 3020 dbSNP
rs1448694300 3031 dbSNP
rs978881410 3036 dbSNP
rs536471415 3038 dbSNP
rs1172534618 3040 dbSNP
rs1043395 3043 dbSNP
rs1160810489 3048 dbSNP
rs1469008768 3049 dbSNP
rs528833746 3051 dbSNP
rs917196588 3052 dbSNP
rs762833550 3055 dbSNP
rs1486809783 3056 dbSNP
rs1255663018 3061 dbSNP
rs1008544721 3062 dbSNP
rs1044531899 3063 dbSNP
rs1286374144 3064 dbSNP
rs566650265 3069 dbSNP
rs1485742113 3071 dbSNP
rs909963646 3074 dbSNP
rs1020565264 3076 dbSNP
rs904662260 3082 dbSNP
rs1346476152 3083 dbSNP
rs1482554455 3094 dbSNP
rs139018750 3095 dbSNP
rs1407865460 3098 dbSNP
rs1037245993 3107 dbSNP
rs1381232908 3107 dbSNP
rs897090134 3110 dbSNP
rs1187531120 3113 dbSNP
rs1439350619 3115 dbSNP
rs1243953500 3120 dbSNP
rs1486295443 3120 dbSNP
rs959080395 3125 dbSNP
rs558719122 3145 dbSNP
rs992833621 3146 dbSNP
rs1332435047 3172 dbSNP
rs577176754 3177 dbSNP
rs1214830156 3179 dbSNP
rs1024225013 3183 dbSNP
rs1267950120 3185 dbSNP
rs998473237 3187 dbSNP
rs5995727 3202 dbSNP
rs1463427566 3205 dbSNP
rs557314237 3206 dbSNP
rs1392776281 3209 dbSNP
rs575474085 3210 dbSNP
rs1284752739 3213 dbSNP
rs889484610 3216 dbSNP
rs1415144164 3218 dbSNP
rs1164618382 3221 dbSNP
rs1175440931 3223 dbSNP
rs1357377070 3229 dbSNP
rs1006510097 3235 dbSNP
rs1429386393 3241 dbSNP
rs150821666 3245 dbSNP
rs1022024644 3246 dbSNP
rs967757214 3252 dbSNP
rs1000381981 3259 dbSNP
rs986392091 3269 dbSNP
rs1375814715 3276 dbSNP
rs1032231581 3289 dbSNP
rs1467055108 3290 dbSNP
rs910299913 3294 dbSNP
rs944488632 3295 dbSNP
rs1308950804 3300 dbSNP
rs1040133215 3303 dbSNP
rs1348149949 3306 dbSNP
rs892112102 3309 dbSNP
rs1371121063 3312 dbSNP
rs560944594 3315 dbSNP
rs1443803036 3323 dbSNP
rs1041978046 3327 dbSNP
rs1462806996 3329 dbSNP
rs904799750 3332 dbSNP
rs1168623912 3333 dbSNP
rs1429298446 3334 dbSNP
rs1195550373 3341 dbSNP
rs1452560095 3344 dbSNP
rs993453169 3345 dbSNP
rs1252282937 3350 dbSNP
rs528222516 3353 dbSNP
rs1000364175 3354 dbSNP
rs1481500659 3355 dbSNP
rs917496097 3358 dbSNP
rs1457636205 3359 dbSNP
rs568114966 3366 dbSNP
rs540214506 3367 dbSNP
rs1014714267 3369 dbSNP
rs1478448312 3372 dbSNP
rs564687874 3376 dbSNP
rs1423105521 3377 dbSNP
rs1411615838 3379 dbSNP
rs139270817 3382 dbSNP
rs1399421254 3394 dbSNP
rs1409489751 3396 dbSNP
rs1376268870 3408 dbSNP
rs1463930498 3409 dbSNP
rs980088154 3411 dbSNP
rs909983004 3413 dbSNP
rs182350372 3414 dbSNP
rs1377082859 3415 dbSNP
rs200272557 3419 dbSNP
rs941404608 3424 dbSNP
rs149582119 3426 dbSNP
rs1327656744 3429 dbSNP
rs755665919 3431 dbSNP
rs1036871048 3433 dbSNP
rs562860257 3436 dbSNP
rs918382681 3439 dbSNP
rs1027512470 3458 dbSNP
rs1485069299 3458 dbSNP
rs372834958 3458 dbSNP
rs933832644 3458 dbSNP
rs1219238245 3460 dbSNP
rs985975327 3463 dbSNP
rs1272602456 3469 dbSNP
rs1240432974 3470 dbSNP
rs113085293 3473 dbSNP
rs910344891 3474 dbSNP
rs1228153526 3476 dbSNP
rs1363387903 3480 dbSNP
rs530208846 3483 dbSNP
rs1051493176 3487 dbSNP
rs1315013208 3493 dbSNP
rs188309362 3494 dbSNP
rs1259311832 3495 dbSNP
rs764368203 3498 dbSNP
rs1317833671 3506 dbSNP
rs7423 3511 dbSNP
rs913680348 3512 dbSNP
rs1475412932 3517 dbSNP
rs1279631877 3521 dbSNP
rs945003890 3521 dbSNP
rs1275372702 3522 dbSNP
rs1452442179 3523 dbSNP
rs1043344487 3524 dbSNP
rs1043449378 3526 dbSNP
rs533993510 3540 dbSNP
rs1245180790 3546 dbSNP
rs866230393 3547 dbSNP
rs1194472262 3549 dbSNP
rs1031846311 3565 dbSNP
rs956437473 3566 dbSNP
rs1296454571 3567 dbSNP
rs1422903778 3568 dbSNP
rs1383988979 3574 dbSNP
rs1382790457 3579 dbSNP
rs41274559 3582 dbSNP
rs1014420498 3587 dbSNP
rs1024583990 3598 dbSNP
rs1476766813 3599 dbSNP
rs1319820070 3607 dbSNP
rs1166831611 3629 dbSNP
rs1014438671 3639 dbSNP
rs1396457140 3645 dbSNP
rs552644208 3646 dbSNP
rs117379545 3656 dbSNP
rs1373277574 3657 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions LCL35
Disease MIMAT0019020
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020022. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acggucgGAGCGGgucg 5'
                 ||:|||    
Target 5' aagauuaCUUGCC---- 3'
 		3 - 15
Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020022
Method / RBP PAR-CLIP / AGO2
Cell line / Condition LCL35 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000328933.5 | 3UTR | UCAAGAUUACUUGCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
108 hsa-miR-4486 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT254654 NF2 neurofibromin 2 2 2
MIRT458684 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT470845 PLXND1 plexin D1 2 2
MIRT493011 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT497264 GRK6 G protein-coupled receptor kinase 6 2 2
MIRT497675 SYNGR1 synaptogyrin 1 2 2
MIRT498219 TLN2 talin 2 2 2
MIRT498310 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT504048 TOMM5 translocase of outer mitochondrial membrane 5 2 2
MIRT519959 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT531521 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT533144 WNT10A Wnt family member 10A 2 2
MIRT533541 TPR translocated promoter region, nuclear basket protein 2 2
MIRT533681 TMEM86A transmembrane protein 86A 2 2
MIRT540321 PIGR polymeric immunoglobulin receptor 2 2
MIRT540719 GUF1 GUF1 homolog, GTPase 2 2
MIRT541566 ZNF43 zinc finger protein 43 2 4
MIRT541787 TBCCD1 TBCC domain containing 1 2 2
MIRT541925 ORC1 origin recognition complex subunit 1 2 4
MIRT542232 FUT9 fucosyltransferase 9 2 2
MIRT542285 POLR3K RNA polymerase III subunit K 2 2
MIRT542299 QTRTD1 queuine tRNA-ribosyltransferase accessory subunit 2 2 4
MIRT542368 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT542441 C3 complement C3 2 4
MIRT542475 APOC3 apolipoprotein C3 2 2
MIRT542535 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542640 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT542788 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT552104 PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A 2 2
MIRT564913 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 2
MIRT568606 ACVR2A activin A receptor type 2A 2 2
MIRT607389 LANCL3 LanC like 3 2 2
MIRT607451 ZNF543 zinc finger protein 543 2 2
MIRT610058 MYBPC1 myosin binding protein C, slow type 2 2
MIRT610793 KLK2 kallikrein related peptidase 2 2 2
MIRT617176 GOSR2 golgi SNAP receptor complex member 2 2 2
MIRT620579 WBSCR27 methyltransferase like 27 2 4
MIRT622085 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT622542 PXMP4 peroxisomal membrane protein 4 2 2
MIRT630009 PDE6B phosphodiesterase 6B 2 2
MIRT631813 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT632721 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT632757 MED28 mediator complex subunit 28 2 2
MIRT634821 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT635255 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT637082 SELPLG selectin P ligand 2 2
MIRT637357 ZNF460 zinc finger protein 460 2 2
MIRT637472 DEFB105B defensin beta 105B 2 4
MIRT637504 DEFB105A defensin beta 105A 2 4
MIRT639022 AAK1 AP2 associated kinase 1 2 2
MIRT641012 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT642170 HEBP2 heme binding protein 2 2 2
MIRT648977 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT650515 UFM1 ubiquitin fold modifier 1 2 2
MIRT650949 INMT indolethylamine N-methyltransferase 2 2
MIRT658354 FAM65B RHO family interacting cell polarization regulator 2 2 2
MIRT660736 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT662191 MEI1 meiotic double-stranded break formation protein 1 2 2
MIRT663045 SLC16A4 solute carrier family 16 member 4 2 2
MIRT664811 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT665161 SF3A1 splicing factor 3a subunit 1 2 4
MIRT665346 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT666493 SBNO1 strawberry notch homolog 1 2 2
MIRT666545 RNF115 ring finger protein 115 2 2
MIRT669351 BMP3 bone morphogenetic protein 3 2 2
MIRT669904 KIAA0754 KIAA0754 2 4
MIRT670323 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT670430 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT670672 KIAA1551 KIAA1551 2 2
MIRT670746 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670998 PTGIS prostaglandin I2 synthase 2 2
MIRT671290 RPL37A ribosomal protein L37a 2 2
MIRT671469 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 2
MIRT671833 STIL STIL, centriolar assembly protein 2 2
MIRT673006 TAF1 TATA-box binding protein associated factor 1 2 2
MIRT675881 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT678625 OLFML2A olfactomedin like 2A 2 2
MIRT678790 NUPL2 nucleoporin like 2 2 2
MIRT679560 LIN9 lin-9 DREAM MuvB core complex component 2 2
MIRT681032 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682480 LIX1L limb and CNS expressed 1 like 2 2
MIRT682758 MDM2 MDM2 proto-oncogene 2 2
MIRT682810 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT682867 C9orf156 tRNA methyltransferase O 2 2
MIRT689233 RPS19 ribosomal protein S19 2 2
MIRT689305 C5AR2 complement component 5a receptor 2 2 2
MIRT689363 ZNF101 zinc finger protein 101 2 2
MIRT689629 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT689654 RBM23 RNA binding motif protein 23 2 2
MIRT690148 PPIL6 peptidylprolyl isomerase like 6 2 2
MIRT691407 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT691847 OSCAR osteoclast associated, immunoglobulin-like receptor 2 2
MIRT692234 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT694320 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT694365 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT696215 LYZ lysozyme 2 2
MIRT697230 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT700487 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT700612 PRKCA protein kinase C alpha 2 2
MIRT702456 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT702990 HERPUD2 HERPUD family member 2 2 2
MIRT703998 EIF5A2 eukaryotic translation initiation factor 5A2 2 2
MIRT704701 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT712481 FSTL3 follistatin like 3 2 2
MIRT712781 ZNF154 zinc finger protein 154 2 2
MIRT714369 HP1BP3 heterochromatin protein 1 binding protein 3 2 2
MIRT722570 C1orf95 stum, mechanosensory transduction mediator homolog 2 2
MIRT722839 C17orf102 chromosome 17 open reading frame 102 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4486 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4486 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Curcumin 969516 NSC32982 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4486 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved sensitive Low Gastric Cancer cell line (SGC-7901)
hsa-mir-4486 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4486 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4486 Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

Error report submission