miRTarBase - #MIRT498362


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pre-miRNA Information
pre-miRNA hsa-mir-6515   
Genomic Coordinates chr19: 12940484 - 12940540
Description Homo sapiens miR-6515 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6515-3p
Sequence 38| UCUCUUCAUCUACCCCCCAG |57
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs75453089 2 dbSNP
rs373354313 3 dbSNP
rs747907310 7 dbSNP
rs769602728 8 dbSNP
rs940767179 9 dbSNP
rs772968331 10 dbSNP
rs762602753 11 dbSNP
rs764010401 12 dbSNP
rs773666399 12 dbSNP
rs761256965 13 dbSNP
rs1320543469 15 dbSNP
rs764459512 16 dbSNP
rs754231139 17 dbSNP
rs878975696 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PRMT3   
Synonyms HRMT1L3
Description protein arginine methyltransferase 3
Transcript NM_001145166   
Other Transcripts NM_001145167 , NM_005788   
Expression
Putative miRNA Targets on PRMT3
3'UTR of PRMT3
(miRNA target sites are highlighted)		 
>PRMT3|NM_001145166|3'UTR
   1 AACAGCCATAAAAGCACACTACCTTGTAGTTTTTAATGTGGGGGTAGAGTGGGTCAGCAGGAGGGAGCTGGTTTTATGTG
  81 AGCAGATGGATGGATGATGGACCCTTTCCTAATGAGCCTCCTCAATAAGAGAGAAGTTCTCATTGTGGGAATCTGACATA
 161 GTTCAGCTGAGGAAGAGAATCAGCTGATCCTCATGGTCTGCCACGTAATCATTTTCTTAGACGTTTGCTCCACCAGATTT
 241 AACCAAATGTAACTCCCACATTGAGTTTATCTATATTGAAAATCATTTACATTGGCCTATATTTGGAAGAGAGATAGTCT
 321 TTTGTTTTTAATAAGTTTCTTACTATAAATTTTAAACAAATTGGTTAGTTATTTGGATATTTTATTAAACTAGTAACACA
 401 GGTACTACACATTTTATTATGGACTCCTCTGAGGAGGAGTTTTTAATTGTATTTGCTAGAAAATCAGGATGTAATAAAGA
 481 TTTGTATAAAAAAACTAAAATATGGAAAAGAGCTTCAGCCTTCATATACAAATCATATATGCAGACAGCCTAGTTGATTA
 561 TCTAGCATACTTAGGGTTCTCATTTTGTAGTTTCTTCCCTCTTTGTGACTATTCCTTAGCCTTATAGATTTCTAGTACTG
 641 CCCAGGAAATCTAATTTCAATACATTTATCCTAGGTTTCATGAAAGTTTTTAAAGATTGGGATAAATATGTACTTATTTA
 721 CTAACGTATTATCTTTTTCAAACCAGATTTATGTGCAAAGGTTAAACATGTAACTGTTACTAAGCAGTCTATAAAGTTGT
 801 CATTTACAATTACTGATTCAATTTGAAATGTAGAATAAAATTTTAATAAAATGTATCCTTATAAAATATTTTAAAAATAT
 881 TGATATTATAAAAGTTTTCAATAAAATATATCAAACAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaccccccaucuACUUCUCu 5'
                      |||:||| 
Target 5' tatggactcctcTGAGGAGg 3'
 418 - 437 124.00 -10.06
2 
miRNA  3' gaccccccaucuaCUUCUCu 5'
                       |||||| 
Target 5' tagttcagctgagGAAGAGa 3'
 159 - 178 120.00 -9.20
3 
miRNA  3' gaccccccaucuaCUUCUCu 5'
                       |||||| 
Target 5' tggcctatatttgGAAGAGa 3'
 293 - 312 120.00 -9.61
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN28859158 2 COSMIC
COSN31561139 14 COSMIC
COSN26435666 22 COSMIC
COSN30180161 45 COSMIC
COSN30447162 45 COSMIC
COSN30453217 90 COSMIC
COSN5259063 97 COSMIC
COSN30470201 109 COSMIC
COSN30470154 110 COSMIC
COSN30172541 130 COSMIC
COSN24381382 133 COSMIC
COSN20092323 143 COSMIC
COSN17183264 220 COSMIC
COSN20108046 512 COSMIC
COSN5825163 756 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs373516049 3 dbSNP
rs763009791 3 dbSNP
rs1199078816 4 dbSNP
rs1421824670 6 dbSNP
rs767529840 9 dbSNP
rs775495797 10 dbSNP
rs752729995 11 dbSNP
rs747944035 15 dbSNP
rs1448909174 20 dbSNP
rs1189216324 21 dbSNP
rs370972379 24 dbSNP
rs763916954 25 dbSNP
rs753589736 27 dbSNP
rs1402513765 30 dbSNP
rs1470726351 31 dbSNP
rs58477713 35 dbSNP
rs899895951 35 dbSNP
rs756922176 39 dbSNP
rs1211003130 40 dbSNP
rs528083235 40 dbSNP
rs375527046 41 dbSNP
rs757956120 42 dbSNP
rs551691220 43 dbSNP
rs367604428 44 dbSNP
rs200448599 45 dbSNP
rs1231533608 47 dbSNP
rs1314083964 50 dbSNP
rs773314203 51 dbSNP
rs537219681 54 dbSNP
rs1362583373 57 dbSNP
rs995354450 62 dbSNP
rs1048672240 66 dbSNP
rs1450215643 69 dbSNP
rs1321727725 70 dbSNP
rs1404875696 72 dbSNP
rs1346004899 77 dbSNP
rs774058203 84 dbSNP
rs781559194 85 dbSNP
rs1464548775 87 dbSNP
rs1209377929 90 dbSNP
rs1467129180 94 dbSNP
rs748516283 96 dbSNP
rs770048187 98 dbSNP
rs1197927321 99 dbSNP
rs1378045100 101 dbSNP
rs1420876166 102 dbSNP
rs1481279658 105 dbSNP
rs1156594127 111 dbSNP
rs557224594 114 dbSNP
rs1457324959 117 dbSNP
rs1290049609 118 dbSNP
rs1387816154 120 dbSNP
rs763066003 122 dbSNP
rs1323439799 124 dbSNP
rs771084706 126 dbSNP
rs1225718248 128 dbSNP
rs1286696000 131 dbSNP
rs11540509 132 dbSNP
rs746881535 132 dbSNP
rs774602023 135 dbSNP
rs567362164 136 dbSNP
rs573046484 143 dbSNP
rs753663385 144 dbSNP
rs761553984 146 dbSNP
rs1490796878 149 dbSNP
rs748435776 152 dbSNP
rs771815670 153 dbSNP
rs553197327 154 dbSNP
rs1243459522 156 dbSNP
rs1384103981 158 dbSNP
rs764925529 159 dbSNP
rs767078456 161 dbSNP
rs914736715 161 dbSNP
rs573152586 162 dbSNP
rs545042855 165 dbSNP
rs980369767 166 dbSNP
rs928864827 167 dbSNP
rs957750041 168 dbSNP
rs1163247367 169 dbSNP
rs1366668882 170 dbSNP
rs1407148619 173 dbSNP
rs1306513967 174 dbSNP
rs779474588 175 dbSNP
rs938371050 176 dbSNP
rs990279952 184 dbSNP
rs1188688863 187 dbSNP
rs751080998 191 dbSNP
rs1248718116 192 dbSNP
rs1176671530 193 dbSNP
rs1481024113 194 dbSNP
rs1309387255 195 dbSNP
rs1320070086 197 dbSNP
rs914764869 199 dbSNP
rs918345205 200 dbSNP
rs1265976767 202 dbSNP
rs538038582 205 dbSNP
rs558822924 206 dbSNP
rs1321161288 216 dbSNP
rs978106778 217 dbSNP
rs1048744831 219 dbSNP
rs7119577 221 dbSNP
rs557033034 223 dbSNP
rs1040995857 224 dbSNP
rs901066586 234 dbSNP
rs768112245 237 dbSNP
rs146842980 240 dbSNP
rs879158786 245 dbSNP
rs1362247397 255 dbSNP
rs1181444285 259 dbSNP
rs944039607 260 dbSNP
rs1399264434 262 dbSNP
rs149067015 266 dbSNP
rs1197400293 268 dbSNP
rs1031641668 274 dbSNP
rs1269580898 279 dbSNP
rs1229537044 283 dbSNP
rs1211380555 300 dbSNP
rs530234061 302 dbSNP
rs143078934 304 dbSNP
rs1259766397 307 dbSNP
rs1239241541 311 dbSNP
rs556136244 312 dbSNP
rs762987726 316 dbSNP
rs1329055835 319 dbSNP
rs1022241623 320 dbSNP
rs149965363 320 dbSNP
rs970266410 327 dbSNP
rs542666488 332 dbSNP
rs1324831636 348 dbSNP
rs1388885306 352 dbSNP
rs1461962661 353 dbSNP
rs776144062 359 dbSNP
rs886968508 360 dbSNP
rs200153164 364 dbSNP
rs1414493639 365 dbSNP
rs1209925209 367 dbSNP
rs928894048 373 dbSNP
rs1004030036 377 dbSNP
rs559222106 385 dbSNP
rs528084403 391 dbSNP
rs1046761208 393 dbSNP
rs1473918066 396 dbSNP
rs551422609 396 dbSNP
rs1180077702 399 dbSNP
rs1445221409 414 dbSNP
rs562457513 431 dbSNP
rs1472976410 435 dbSNP
rs761365035 437 dbSNP
rs1159725213 438 dbSNP
rs1390766304 439 dbSNP
rs1465938821 447 dbSNP
rs906430278 449 dbSNP
rs1001832488 452 dbSNP
rs1323708045 454 dbSNP
rs1048129754 470 dbSNP
rs1333343498 473 dbSNP
rs1325205744 477 dbSNP
rs1359348374 484 dbSNP
rs1327763152 488 dbSNP
rs1391066775 488 dbSNP
rs910933338 488 dbSNP
rs1335049137 489 dbSNP
rs1469340454 496 dbSNP
rs1305825368 497 dbSNP
rs1425886410 498 dbSNP
rs575221791 499 dbSNP
rs1174392736 503 dbSNP
rs942566696 521 dbSNP
rs1033268152 527 dbSNP
rs1474361181 535 dbSNP
rs536246984 539 dbSNP
rs1188946164 547 dbSNP
rs183368804 548 dbSNP
rs373171875 550 dbSNP
rs1202704543 568 dbSNP
rs1442655472 591 dbSNP
rs935226634 594 dbSNP
rs1053147017 598 dbSNP
rs1337989416 599 dbSNP
rs773356153 602 dbSNP
rs1297563124 605 dbSNP
rs891775288 609 dbSNP
rs1367864189 610 dbSNP
rs1329436956 615 dbSNP
rs1452103111 617 dbSNP
rs879018821 625 dbSNP
rs115707050 626 dbSNP
rs1279841205 629 dbSNP
rs967975036 650 dbSNP
rs977595813 654 dbSNP
rs567410000 656 dbSNP
rs912821289 659 dbSNP
rs965588315 663 dbSNP
rs1383091989 672 dbSNP
rs1182759702 684 dbSNP
rs186549366 693 dbSNP
rs1035813774 694 dbSNP
rs960319901 697 dbSNP
rs1436788089 701 dbSNP
rs1251364655 705 dbSNP
rs1483391244 718 dbSNP
rs921296815 727 dbSNP
rs1025760383 737 dbSNP
rs931287288 742 dbSNP
rs1289991825 745 dbSNP
rs553425216 746 dbSNP
rs1380136884 754 dbSNP
rs1286219731 755 dbSNP
rs1440112441 759 dbSNP
rs566901118 771 dbSNP
rs939861227 777 dbSNP
rs191424913 786 dbSNP
rs906462868 789 dbSNP
rs937969793 803 dbSNP
rs1415502910 810 dbSNP
rs1435796538 820 dbSNP
rs1469317731 823 dbSNP
rs910975227 832 dbSNP
rs1183752882 834 dbSNP
rs1484293093 841 dbSNP
rs1267443052 842 dbSNP
rs942392694 847 dbSNP
rs1054958722 849 dbSNP
rs1322772586 856 dbSNP
rs1292281934 857 dbSNP
rs35736700 858 dbSNP
rs754319265 858 dbSNP
rs1328761731 860 dbSNP
rs1289024488 861 dbSNP
rs1409897122 866 dbSNP
rs893502926 871 dbSNP
rs868580770 876 dbSNP
rs1292936009 882 dbSNP
rs1021142941 883 dbSNP
rs1052367140 893 dbSNP
rs572492773 912 dbSNP
rs538627650 916 dbSNP
rs1412280201 925 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions EF3D-AGO2
Disease MIMAT0025487
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1020021. RNA binding protein: AGO2. Condition:EBV B95-8-infected ...

- Skalsky RL; Corcoran DL; Gottwein E; Frank et al., 2012, PLoS pathogens.

Article - Skalsky RL; Corcoran DL; Gottwein E; Frank et al.
- PLoS pathogens, 2012
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.
LinkOut: [PMID: 22291592]
CLIP-seq Support 1 for dataset GSM1020021
Method / RBP PAR-CLIP / AGO2
Cell line / Condition EF3D-AGO2 / EBV B95-8-infected, 4-thiouridine, RNase T1
Location of target site ENST00000331079.6 | 3UTR | UUGGCCUAUAUUUGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22291592 / GSE41437
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
181 hsa-miR-6515-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059268 CELF1 CUGBP Elav-like family member 1 2 2
MIRT063207 ADIPOR2 adiponectin receptor 2 2 2
MIRT118973 SOWAHC sosondowah ankyrin repeat domain family member C 2 2
MIRT234292 PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta 2 2
MIRT305089 SRPRB SRP receptor beta subunit 2 4
MIRT316916 ATXN1 ataxin 1 2 2
MIRT320191 ITGB8 integrin subunit beta 8 2 2
MIRT366351 SCML2 Scm polycomb group protein like 2 2 2
MIRT443924 ZNF99 zinc finger protein 99 2 6
MIRT445622 CLIC4 chloride intracellular channel 4 2 2
MIRT447378 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2 2
MIRT463191 ZNF275 zinc finger protein 275 2 4
MIRT472656 NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 2 4
MIRT478997 COLGALT1 collagen beta(1-O)galactosyltransferase 1 2 2
MIRT497221 MORC2 MORC family CW-type zinc finger 2 2 2
MIRT498343 PRELID2 PRELI domain containing 2 2 2
MIRT498362 PRMT3 protein arginine methyltransferase 3 2 2
MIRT501097 SLC5A6 solute carrier family 5 member 6 2 4
MIRT505086 ZBTB18 zinc finger and BTB domain containing 18 2 6
MIRT507527 DSTN destrin, actin depolymerizing factor 2 4
MIRT525793 SOD2 superoxide dismutase 2 2 2
MIRT544401 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT558808 CDK6 cyclin dependent kinase 6 2 4
MIRT559126 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT566474 PEG10 paternally expressed 10 2 2
MIRT607261 GRAMD1B GRAM domain containing 1B 2 4
MIRT609251 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT610065 MYBPC1 myosin binding protein C, slow type 2 2
MIRT610135 FOXI2 forkhead box I2 2 4
MIRT610280 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT611285 PAGR1 PAXIP1 associated glutamate rich protein 1 2 4
MIRT611353 KIAA2018 upstream transcription factor family member 3 2 2
MIRT611812 FCRL4 Fc receptor like 4 2 2
MIRT611898 TRPC3 transient receptor potential cation channel subfamily C member 3 2 2
MIRT612749 MYOCD myocardin 2 2
MIRT614180 FAM53B family with sequence similarity 53 member B 2 2
MIRT614825 PVRL4 nectin cell adhesion molecule 4 2 2
MIRT616702 UBXN2A UBX domain protein 2A 2 2
MIRT616970 HMGB1 high mobility group box 1 2 2
MIRT616992 COL19A1 collagen type XIX alpha 1 chain 2 2
MIRT617132 ZNF556 zinc finger protein 556 2 4
MIRT617595 NUDT5 nudix hydrolase 5 2 4
MIRT617997 KSR2 kinase suppressor of ras 2 2 2
MIRT619451 NUP214 nucleoporin 214 2 2
MIRT619507 TXLNB taxilin beta 2 2
MIRT619547 GABRG2 gamma-aminobutyric acid type A receptor gamma2 subunit 2 2
MIRT619719 FCF1 FCF1, rRNA-processing protein 2 2
MIRT619806 CDC42EP4 CDC42 effector protein 4 2 2
MIRT619939 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT620456 CENPN centromere protein N 2 2
MIRT621054 DGKD diacylglycerol kinase delta 2 2
MIRT622730 PITPNM3 PITPNM family member 3 2 2
MIRT623010 ONECUT3 one cut homeobox 3 2 2
MIRT623432 KIAA1161 myogenesis regulating glycosidase (putative) 2 2
MIRT624379 CDH4 cadherin 4 2 2
MIRT624493 CABP4 calcium binding protein 4 2 2
MIRT625740 MTSS1 MTSS1, I-BAR domain containing 2 2
MIRT627048 HOXA13 homeobox A13 2 2
MIRT630857 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT632232 VTA1 vesicle trafficking 1 2 2
MIRT632978 E2F2 E2F transcription factor 2 2 2
MIRT635721 CCL16 C-C motif chemokine ligand 16 2 2
MIRT636489 GRIN2B glutamate ionotropic receptor NMDA type subunit 2B 2 2
MIRT637743 POLR3K RNA polymerase III subunit K 2 2
MIRT639610 SLC25A32 solute carrier family 25 member 32 2 4
MIRT639878 STC1 stanniocalcin 1 2 2
MIRT640507 ANTXR1 anthrax toxin receptor 1 2 2
MIRT640910 RAB13 RAB13, member RAS oncogene family 2 2
MIRT641864 STOML1 stomatin like 1 2 2
MIRT641989 OXSR1 oxidative stress responsive 1 2 2
MIRT642897 CASP1 caspase 1 2 2
MIRT643210 TYW3 tRNA-yW synthesizing protein 3 homolog 2 4
MIRT643970 FHL2 four and a half LIM domains 2 2 4
MIRT644517 TADA2A transcriptional adaptor 2A 2 2
MIRT644564 SPOP speckle type BTB/POZ protein 2 2
MIRT644738 CCDC174 coiled-coil domain containing 174 2 2
MIRT645518 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT645597 MRPS15 mitochondrial ribosomal protein S15 2 2
MIRT646262 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT646467 PRDM10 PR/SET domain 10 2 2
MIRT646623 CENPL centromere protein L 2 2
MIRT646797 EVC2 EvC ciliary complex subunit 2 2 2
MIRT647188 ANKRD45 ankyrin repeat domain 45 2 2
MIRT647254 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647895 EPN2 epsin 2 2 2
MIRT648129 SEMA3E semaphorin 3E 2 4
MIRT648133 JAGN1 jagunal homolog 1 2 2
MIRT648361 AKIP1 A-kinase interacting protein 1 2 2
MIRT648574 CAPN13 calpain 13 2 2
MIRT648622 CYB561A3 cytochrome b561 family member A3 2 2
MIRT649441 HIBADH 3-hydroxyisobutyrate dehydrogenase 2 2
MIRT649456 WDR70 WD repeat domain 70 2 2
MIRT649479 CLDN16 claudin 16 2 2
MIRT649552 FAM20B FAM20B, glycosaminoglycan xylosylkinase 2 2
MIRT650060 CCDC134 coiled-coil domain containing 134 2 2
MIRT650272 KLF2 Kruppel like factor 2 2 4
MIRT650290 PYCARD PYD and CARD domain containing 2 2
MIRT651327 ZCCHC2 zinc finger CCHC-type containing 2 2 2
MIRT652194 TRIM39 tripartite motif containing 39 2 2
MIRT652284 TNS4 tensin 4 2 2
MIRT652386 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT652702 THBS2 thrombospondin 2 2 2
MIRT652782 TEAD1 TEA domain transcription factor 1 2 2
MIRT653087 SSR3 signal sequence receptor subunit 3 2 2
MIRT653836 SHISA9 shisa family member 9 2 2
MIRT654147 RPAP2 RNA polymerase II associated protein 2 2 2
MIRT655016 PLA2G16 phospholipase A2 group XVI 2 2
MIRT655065 PKIA cAMP-dependent protein kinase inhibitor alpha 2 2
MIRT655217 PFKM phosphofructokinase, muscle 2 2
MIRT655267 PER2 period circadian clock 2 2 2
MIRT655772 NPTX1 neuronal pentraxin 1 2 2
MIRT655791 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT656556 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT656831 KLF8 Kruppel like factor 8 2 2
MIRT656887 KIF1C kinesin family member 1C 2 2
MIRT657295 HOXB5 homeobox B5 2 2
MIRT657346 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT657967 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT658082 FOXR2 forkhead box R2 2 2
MIRT658133 FMN1 formin 1 2 2
MIRT658163 FCHSD1 FCH and double SH3 domains 1 2 2
MIRT658787 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT658928 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT659989 C2CD2L C2CD2 like 2 2
MIRT660012 C1orf115 chromosome 1 open reading frame 115 2 4
MIRT660295 BICC1 BicC family RNA binding protein 1 2 2
MIRT662571 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT664406 AQP3 aquaporin 3 (Gill blood group) 2 2
MIRT667402 MIB1 mindbomb E3 ubiquitin protein ligase 1 2 2
MIRT667621 LIMCH1 LIM and calponin homology domains 1 2 2
MIRT668421 FAM217B family with sequence similarity 217 member B 2 2
MIRT668524 ESRRG estrogen related receptor gamma 2 2
MIRT668680 DR1 down-regulator of transcription 1 2 2
MIRT695383 NSA2 NSA2, ribosome biogenesis homolog 2 2
MIRT702511 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT709032 KBTBD13 kelch repeat and BTB domain containing 13 2 2
MIRT710831 PLEKHO2 pleckstrin homology domain containing O2 2 2
MIRT710967 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711145 TMEM174 transmembrane protein 174 2 2
MIRT711176 EMCN endomucin 2 2
MIRT711205 SMIM14 small integral membrane protein 14 2 2
MIRT711589 SETD1A SET domain containing 1A 2 2
MIRT711751 DTX1 deltex E3 ubiquitin ligase 1 2 2
MIRT712258 PTPRN2 protein tyrosine phosphatase, receptor type N2 2 2
MIRT712376 MTPN myotrophin 2 2
MIRT713780 ZNF460 zinc finger protein 460 2 2
MIRT714560 LMTK2 lemur tyrosine kinase 2 2 2
MIRT714983 RAB21 RAB21, member RAS oncogene family 2 2
MIRT716253 PALM2 paralemmin 2 2 2
MIRT716362 RPS9 ribosomal protein S9 2 2
MIRT716485 SAMD7 sterile alpha motif domain containing 7 2 2
MIRT716640 DPY19L4 dpy-19 like 4 2 2
MIRT717034 KRTAP4-9 keratin associated protein 4-9 2 2
MIRT717422 SURF6 surfeit 6 2 2
MIRT717891 GBP4 guanylate binding protein 4 2 2
MIRT718646 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT719230 ARL11 ADP ribosylation factor like GTPase 11 2 2
MIRT719279 SETD7 SET domain containing lysine methyltransferase 7 2 2
MIRT719353 GDF7 growth differentiation factor 7 2 2
MIRT719513 TMEM175 transmembrane protein 175 2 2
MIRT719618 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT719882 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT720184 CMC4 C-X9-C motif containing 4 2 2
MIRT720249 FAM83F family with sequence similarity 83 member F 2 2
MIRT720343 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT720487 TMEM178B transmembrane protein 178B 2 2
MIRT720937 PPP1R3E protein phosphatase 1 regulatory subunit 3E 2 2
MIRT721168 NSG1 neuronal vesicle trafficking associated 1 2 2
MIRT721499 THRB thyroid hormone receptor beta 2 2
MIRT721518 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT721570 SLC5A12 solute carrier family 5 member 12 2 2
MIRT721865 CENPJ centromere protein J 2 2
MIRT721871 RHOH ras homolog family member H 2 2
MIRT722330 PKHD1 PKHD1, fibrocystin/polyductin 2 2
MIRT722494 PNKD paroxysmal nonkinesigenic dyskinesia 2 2
MIRT722775 KCNK5 potassium two pore domain channel subfamily K member 5 2 2
MIRT723967 GPR146 G protein-coupled receptor 146 2 2
MIRT724488 CSNK1A1 casein kinase 1 alpha 1 2 2
MIRT724748 ZNF391 zinc finger protein 391 2 2
MIRT725274 OSTM1 osteopetrosis associated transmembrane protein 1 2 2
MIRT725373 MTF2 metal response element binding transcription factor 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6515-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-6515-3p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-6515-3p Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-6515-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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