>EHD4|NM_139265|3'UTR
   1 GGGGTGGGCTGCAGAACGGGGTGGGAACTGGGGGACCTGGGCCTCAGGCCTGCTCCACCACTGACTCACCGAATGACCTT
  81 GGGCAAGGCACTGCCCTCTCTGTGCCTTGGTTTCCCCATCTGTAGAATGGGGAGGGTGGACACTGGAAACTAGATGACTT
 161 CTTTCACCTCCAAAATTCCCTTAGTTTCTATGAAAATATTGGGGGTAGGGGGGTGGATTAGGAGATTGAAGGGTTGAGAA
 241 GAAAGAGAAATTGTCCAAAGAGTCCTCAGAACCTGCCTGGAGAAATGCGCATGGGGGTGGGCCTGGTAAGTCCCAGGAAC
 321 CACAGGAAGTGAGCTAAGGCTCACCCAGAGCAGCTGGGTCTCCAGGCTGCCTGGGCTTTTTGTCCTCATGAACAACTCTG
 401 GAGCAGCTGTCTGTCCCTCAGAGGGCACCTGGAGGCAGCAAAGATTATCTTATTTATTTTATTTTGTTTTCTGCTATATT
 481 TAGAGTGGCAAAAAAATAGAGCAGAGGGTTTCTGCTGTCTCCAGACTGTCTACCAAAGAGAAGGCGACAGATGCCTCCTG
 561 GGTTTGGAAGGGGGATGCACTGTGGATCTGCCATCCATTCTGCAGTCTCCAGCAGAGCAGGCAGTCAGGCCCCAGCGTGC
 641 CTCCATCCCAGTGCCCCGATGACCATCTGGTCAGCCCTCCCAACCTCCCTTCCAGGGGGCTTACCAGCAAAGCCATATTC
 721 GGCTAGGAATTTGGAATTCACAACCTTTATTAACCCCTGGCAAAACTTCCCGTTTGCATGTCAAATCACATTGAAGCCTG
 801 AAAATTAGCTTTTCTTACTGGTTTTTCCAATAAGTAATAGCAAAGCCCACTTATCATACTTAAACTACAGTAAAGAAAAG
 881 AGGTGGTTCTCTGCAGTGATCGTTTAGTGTGGCCCTCAAACATTAAATATCCCGAGGTCTCCTTGGTGGGTGGCAGGATT
 961 TAAATTCAATCAAATCCTGTCCTAGTGTGTGCAGTGTCTTCGGCCCTGTGGACACAGGTGAATGAGGGACCAGCCCTGCC
1041 CTGGGCTGTTGAGAAGAGATCAGTCCACCCAGAGTTAGACATTGTTTTTGTAGAAAACAGGCATTTATTATGTCTAGGGT
1121 TTTGTGTTTTTTTTTTTTCCTTACAGGATAAAAGCCTTTATACAGAAACAAAATGGAACCTTTCATATAAAACCTTTTCT
1201 TTAAAAAAAAAAAAA

ID	Duplex structure	Position	Score	MFE
1	miRNA 3' uuCACCC--GA--CCCUAGGCCCGac 5' ||||| || |||| |:|||| Target 5' ggGTGGGAACTGGGGGACCTGGGCct 3'	19 - 44	136.00	-29.00
2	miRNA 3' uucACCC-GA--CCCUA--GGCCCGAc 5' |||| || || | |:||||| Target 5' agcTGGGTCTCCAGGCTGCCTGGGCTt 3'	352 - 378	135.00	-23.19
3	miRNA 3' uucacccgacccuaGGCCCGAc 5' |:||||| Target 5' ggaccagccctgccCTGGGCTg 3'	1027 - 1048	124.00	-16.00

Mutant ID	Mutant Position	Mutant Source
COSN31499328	7	COSMIC
COSN20047570	46	COSMIC
COSN27626198	113	COSMIC
COSN31543844	178	COSMIC
COSN29630490	207	COSMIC
COSN31488413	241	COSMIC
COSN31592824	288	COSMIC
COSN31583919	289	COSMIC
COSN26642194	297	COSMIC
COSN31607312	480	COSMIC
COSN31597515	489	COSMIC
COSN26640153	512	COSMIC
COSN31521129	540	COSMIC
COSN5754452	629	COSMIC
COSN16508133	713	COSMIC
COSN18723459	1568	COSMIC
COSN16090526	1765	COSMIC
COSN17226108	2136	COSMIC
COSN23070950	3066	COSMIC
COSN28954794	3384	COSMIC
COSN22792123	4099	COSMIC
COSN6272878	4307	COSMIC
COSN6272877	4421	COSMIC
COSN31646589	4606	COSMIC
rs117990941	2939	GWAS

Mutant ID	Mutant Position	Mutant Source
rs1247608254	1	dbSNP
rs747406321	3	dbSNP
rs1315584007	8	dbSNP
rs775988621	11	dbSNP
rs1279049148	13	dbSNP
rs200600029	17	dbSNP
rs778505586	18	dbSNP
rs1281498736	19	dbSNP
rs756909109	21	dbSNP
rs1346407566	28	dbSNP
rs953873763	29	dbSNP
rs1295008398	31	dbSNP
rs531962895	34	dbSNP
rs777215958	35	dbSNP
rs1318869854	41	dbSNP
rs1458794764	42	dbSNP
rs1298974166	45	dbSNP
rs1426542726	48	dbSNP
rs1175117188	49	dbSNP
rs544194547	52	dbSNP
rs897037053	53	dbSNP
rs1043105085	54	dbSNP
rs946611219	56	dbSNP
rs112415087	59	dbSNP
rs915024473	70	dbSNP
rs367676526	71	dbSNP
rs1002683793	79	dbSNP
rs1401462154	84	dbSNP
rs937902352	86	dbSNP
rs552787030	90	dbSNP
rs1364162168	91	dbSNP
rs574286230	94	dbSNP
rs1233440197	98	dbSNP
rs981800083	99	dbSNP
rs948152371	103	dbSNP
rs1232463309	109	dbSNP
rs1253698434	112	dbSNP
rs950342854	117	dbSNP
rs919046482	120	dbSNP
rs560617600	123	dbSNP
rs963588731	134	dbSNP
rs1320094510	149	dbSNP
rs1463815769	151	dbSNP
rs1195968976	152	dbSNP
rs773716100	161	dbSNP
rs1268511648	165	dbSNP
rs1007831074	182	dbSNP
rs555780580	188	dbSNP
rs954931063	190	dbSNP
rs1326831044	199	dbSNP
rs1030527134	200	dbSNP
rs1365573464	208	dbSNP
rs748154378	209	dbSNP
rs936931143	210	dbSNP
rs903189587	213	dbSNP
rs924168006	214	dbSNP
rs978250071	214	dbSNP
rs112926893	216	dbSNP
rs912719701	218	dbSNP
rs776754596	226	dbSNP
rs868683908	232	dbSNP
rs1197266328	233	dbSNP
rs529615944	256	dbSNP
rs1454106210	260	dbSNP
rs780499310	266	dbSNP
rs953820008	272	dbSNP
rs893659189	288	dbSNP
rs186046802	289	dbSNP
rs961301990	290	dbSNP
rs1208551027	321	dbSNP
rs1015540703	329	dbSNP
rs543947448	331	dbSNP
rs367728044	332	dbSNP
rs575115017	339	dbSNP
rs1022794260	340	dbSNP
rs1012747201	342	dbSNP
rs1340048189	346	dbSNP
rs1055337502	348	dbSNP
rs1271846110	360	dbSNP
rs937811831	361	dbSNP
rs936653262	373	dbSNP
rs1398631937	376	dbSNP
rs1410366345	387	dbSNP
rs902504402	398	dbSNP
rs558366929	409	dbSNP
rs1348120119	413	dbSNP
rs1230887683	417	dbSNP
rs1234712739	425	dbSNP
rs1313049297	432	dbSNP
rs927887294	438	dbSNP
rs1321478285	446	dbSNP
rs1243152742	449	dbSNP
rs1042647880	453	dbSNP
rs1369991955	466	dbSNP
rs182453840	476	dbSNP
rs151068126	479	dbSNP
rs1046342074	481	dbSNP
rs1249667372	483	dbSNP
rs912764450	484	dbSNP
rs1398333357	486	dbSNP
rs1413417781	487	dbSNP
rs928988366	491	dbSNP
rs549032077	497	dbSNP
rs918893183	503	dbSNP
rs572848902	506	dbSNP
rs963437440	507	dbSNP
rs552982821	508	dbSNP
rs1303058803	515	dbSNP
rs761033991	519	dbSNP
rs1015258909	532	dbSNP
rs773392452	537	dbSNP
rs986733421	542	dbSNP
rs1298124856	545	dbSNP
rs954857557	546	dbSNP
rs1228276153	548	dbSNP
rs768865009	551	dbSNP
rs1030581089	555	dbSNP
rs1273173959	579	dbSNP
rs999056198	580	dbSNP
rs1210994881	586	dbSNP
rs190229038	592	dbSNP
rs80139520	593	dbSNP
rs555060407	594	dbSNP
rs1188535953	597	dbSNP
rs1249629541	602	dbSNP
rs1011674015	614	dbSNP
rs895241192	618	dbSNP
rs1187838200	622	dbSNP
rs1388316438	624	dbSNP
rs1274425879	627	dbSNP
rs1416103880	629	dbSNP
rs894579691	633	dbSNP
rs1198683656	635	dbSNP
rs1358096647	637	dbSNP
rs1347008893	644	dbSNP
rs758164334	646	dbSNP
rs1280827107	647	dbSNP
rs1236188907	650	dbSNP
rs1032413122	657	dbSNP
rs1034418041	658	dbSNP
rs1366356163	659	dbSNP
rs1434902448	663	dbSNP
rs1296041508	667	dbSNP
rs1373747711	670	dbSNP
rs1220330902	677	dbSNP
rs1277952180	687	dbSNP
rs1002073943	693	dbSNP
rs906355163	698	dbSNP
rs1218183832	700	dbSNP
rs1443122716	700	dbSNP
rs1337628212	701	dbSNP
rs535035027	704	dbSNP
rs1332225103	715	dbSNP
rs745682046	720	dbSNP
rs1046353140	721	dbSNP
rs929169876	723	dbSNP
rs1245973951	737	dbSNP
rs897511204	738	dbSNP
rs16972233	743	dbSNP
rs1423822883	745	dbSNP
rs1431005102	754	dbSNP
rs1160913924	755	dbSNP
rs1389009373	756	dbSNP
rs1042370123	769	dbSNP
rs778843885	771	dbSNP
rs1008439110	772	dbSNP
rs74573199	775	dbSNP
rs1418241150	778	dbSNP
rs184932319	784	dbSNP
rs532741291	785	dbSNP
rs1225599696	790	dbSNP
rs910317111	795	dbSNP
rs1048166	803	dbSNP
rs1234145945	809	dbSNP
rs373468493	818	dbSNP
rs920074006	825	dbSNP
rs1222190686	828	dbSNP
rs1485329910	837	dbSNP
rs1246113951	841	dbSNP
rs1487219133	850	dbSNP
rs1258117729	854	dbSNP
rs933525449	867	dbSNP
rs923401404	868	dbSNP
rs1412088224	869	dbSNP
rs570599203	875	dbSNP
rs1472033998	880	dbSNP
rs146645752	882	dbSNP
rs530933574	894	dbSNP
rs967573886	901	dbSNP
rs748764067	902	dbSNP
rs560689198	905	dbSNP
rs1406372132	916	dbSNP
rs1323466956	930	dbSNP
rs990577566	931	dbSNP
rs1224567420	933	dbSNP
rs1048175	934	dbSNP
rs1308662262	939	dbSNP
rs1034879776	956	dbSNP
rs908209816	969	dbSNP
rs1226766261	971	dbSNP
rs530549576	978	dbSNP
rs1358185979	979	dbSNP
rs1414222936	981	dbSNP
rs1356724082	982	dbSNP
rs1288889630	991	dbSNP
rs1319798086	993	dbSNP
rs1207241811	994	dbSNP
rs376230912	1001	dbSNP
rs1482469294	1002	dbSNP
rs1179549118	1008	dbSNP
rs1024791005	1027	dbSNP
rs755795184	1030	dbSNP
rs897767978	1038	dbSNP
rs915808175	1042	dbSNP
rs1344993877	1045	dbSNP
rs1160237699	1048	dbSNP
rs1412104783	1051	dbSNP
rs1432125601	1052	dbSNP
rs373462761	1053	dbSNP
rs1408142847	1054	dbSNP
rs1336397143	1055	dbSNP
rs957257417	1060	dbSNP
rs1409671879	1069	dbSNP
rs1283337035	1102	dbSNP
rs752440965	1108	dbSNP
rs767095445	1111	dbSNP
rs763333067	1112	dbSNP
rs1162237151	1118	dbSNP
rs1280143318	1127	dbSNP
rs180945937	1127	dbSNP
rs966727701	1128	dbSNP
rs1417863070	1130	dbSNP
rs112861844	1139	dbSNP
rs1390174916	1139	dbSNP
rs1428386959	1139	dbSNP
rs796198698	1139	dbSNP
rs1174336944	1143	dbSNP
rs1190002765	1146	dbSNP
rs1414085761	1166	dbSNP
rs763664862	1172	dbSNP
rs1332492121	1174	dbSNP
rs888781458	1179	dbSNP
rs1298063123	1180	dbSNP
rs145878392	1189	dbSNP
rs1216207412	1197	dbSNP
rs542521757	1199	dbSNP
rs1199502841	1208	dbSNP
rs997497078	1218	dbSNP
rs1466526986	1219	dbSNP
rs773449687	1221	dbSNP
rs1247815626	1223	dbSNP
rs923453729	1229	dbSNP
rs1038508094	1234	dbSNP
rs796274598	1238	dbSNP
rs190439698	1239	dbSNP
rs908261608	1240	dbSNP
rs1045442781	1244	dbSNP
rs554692117	1250	dbSNP
rs990406359	1251	dbSNP
rs991456849	1254	dbSNP
rs765764913	1274	dbSNP
rs1289868779	1277	dbSNP
rs538238263	1284	dbSNP
rs1303379932	1285	dbSNP
rs1346661327	1286	dbSNP
rs568973990	1289	dbSNP
rs745719507	1292	dbSNP
rs575846448	1293	dbSNP
rs981544691	1295	dbSNP
rs971445357	1300	dbSNP
rs1460538655	1302	dbSNP
rs1025723331	1308	dbSNP
rs993355344	1309	dbSNP
rs1394613449	1311	dbSNP
rs11070353	1324	dbSNP
rs1008714046	1329	dbSNP
rs1212133816	1333	dbSNP
rs955433470	1336	dbSNP
rs148940920	1337	dbSNP
rs1197287897	1344	dbSNP
rs1006105117	1345	dbSNP
rs1473018012	1352	dbSNP
rs1418683634	1354	dbSNP
rs997108294	1355	dbSNP
rs1186949414	1356	dbSNP
rs888796825	1357	dbSNP
rs1050020839	1358	dbSNP
rs1017126918	1374	dbSNP
rs757264024	1386	dbSNP
rs145703815	1390	dbSNP
rs1250836543	1395	dbSNP
rs1386154921	1395	dbSNP
rs1300695395	1402	dbSNP
rs571387207	1408	dbSNP
rs1469042972	1410	dbSNP
rs1045514770	1413	dbSNP
rs535437137	1429	dbSNP
rs1247352846	1431	dbSNP
rs1266414608	1432	dbSNP
rs1275168231	1437	dbSNP
rs946238512	1441	dbSNP
rs1220942543	1447	dbSNP
rs1254030820	1453	dbSNP
rs1181711812	1459	dbSNP
rs1483450181	1459	dbSNP
rs1248767762	1460	dbSNP
rs547290223	1461	dbSNP
rs1055832064	1462	dbSNP
rs1368855847	1475	dbSNP
rs1457311524	1476	dbSNP
rs1161643135	1486	dbSNP
rs11636178	1495	dbSNP
rs1409968776	1496	dbSNP
rs747115494	1498	dbSNP
rs1369256449	1508	dbSNP
rs977244691	1521	dbSNP
rs945911091	1538	dbSNP
rs911716009	1539	dbSNP
rs1439751940	1541	dbSNP
rs1244394913	1544	dbSNP
rs1394731069	1561	dbSNP
rs927294145	1565	dbSNP
rs371293937	1568	dbSNP
rs981471379	1572	dbSNP
rs1249705792	1579	dbSNP
rs1256563753	1579	dbSNP
rs34607649	1579	dbSNP
rs398118793	1579	dbSNP
rs1443833655	1581	dbSNP
rs1181667884	1583	dbSNP
rs1460014029	1585	dbSNP
rs1391863540	1602	dbSNP
rs971371821	1613	dbSNP
rs1169069726	1615	dbSNP
rs1352289647	1617	dbSNP
rs1467232708	1618	dbSNP
rs567928089	1623	dbSNP
rs918714569	1624	dbSNP
rs972805680	1628	dbSNP
rs1450999232	1643	dbSNP
rs187158818	1646	dbSNP
rs1366486378	1649	dbSNP
rs369137278	1659	dbSNP
rs962973240	1673	dbSNP
rs1017219978	1680	dbSNP
rs1211064845	1688	dbSNP
rs765240326	1688	dbSNP
rs1460704649	1689	dbSNP
rs1201475311	1701	dbSNP
rs1393070367	1709	dbSNP
rs1004456573	1722	dbSNP
rs1192739991	1727	dbSNP
rs887308432	1731	dbSNP
rs1024891763	1737	dbSNP
rs1454908059	1739	dbSNP
rs1006562721	1744	dbSNP
rs1467918278	1745	dbSNP
rs879317841	1747	dbSNP
rs1389881060	1748	dbSNP
rs534030475	1753	dbSNP
rs953348976	1755	dbSNP
rs1175618933	1763	dbSNP
rs564647844	1764	dbSNP
rs182600142	1765	dbSNP
rs1369806630	1766	dbSNP
rs901506464	1768	dbSNP
rs745618976	1769	dbSNP
rs1321609970	1774	dbSNP
rs7166358	1776	dbSNP
rs1009947674	1779	dbSNP
rs911728713	1780	dbSNP
rs1214967292	1781	dbSNP
rs1240351309	1782	dbSNP
rs559317135	1784	dbSNP
rs1191213974	1792	dbSNP
rs1489425213	1792	dbSNP
rs1371359950	1793	dbSNP
rs893311916	1799	dbSNP
rs1054602359	1800	dbSNP
rs1001826720	1801	dbSNP
rs987673896	1801	dbSNP
rs1302949289	1809	dbSNP
rs1160978524	1813	dbSNP
rs934104000	1821	dbSNP
rs542783365	1823	dbSNP
rs573898185	1837	dbSNP
rs921324938	1838	dbSNP
rs149801241	1842	dbSNP
rs962733790	1843	dbSNP
rs1372000376	1847	dbSNP
rs749276012	1848	dbSNP
rs777398418	1850	dbSNP
rs544624255	1851	dbSNP
rs1373530666	1852	dbSNP
rs1289282208	1853	dbSNP
rs1648810	1854	dbSNP
rs188997143	1860	dbSNP
rs1435096106	1867	dbSNP
rs951570766	1872	dbSNP
rs950065356	1873	dbSNP
rs752176811	1875	dbSNP
rs1396585943	1876	dbSNP
rs973232682	1877	dbSNP
rs1489666964	1882	dbSNP
rs562530548	1884	dbSNP
rs559118420	1886	dbSNP
rs909943304	1898	dbSNP
rs984664264	1899	dbSNP
rs1178995947	1900	dbSNP
rs1469316651	1907	dbSNP
rs1175795565	1908	dbSNP
rs999892562	1914	dbSNP
rs1485007236	1916	dbSNP
rs953211748	1922	dbSNP
rs904235213	1927	dbSNP
rs1350510433	1928	dbSNP
rs1041323772	1934	dbSNP
rs1024924463	1936	dbSNP
rs1259272626	1937	dbSNP
rs1431776104	1938	dbSNP
rs539103431	1940	dbSNP
rs1010115224	1941	dbSNP
rs201803000	1945	dbSNP
rs753130379	1947	dbSNP
rs1277516002	1948	dbSNP
rs965684585	1949	dbSNP
rs1019882547	1951	dbSNP
rs147829961	1952	dbSNP
rs1291026448	1953	dbSNP
rs892917116	1955	dbSNP
rs553321821	1971	dbSNP
rs750799246	1972	dbSNP
rs1206599851	1974	dbSNP
rs921772852	1976	dbSNP
rs1274755394	1977	dbSNP
rs1039845803	1978	dbSNP
rs1353560710	1986	dbSNP
rs1001751932	1991	dbSNP
rs1473361992	1997	dbSNP
rs536851392	2000	dbSNP
rs906023261	2009	dbSNP
rs1312200041	2010	dbSNP
rs1383856013	2011	dbSNP
rs1451893839	2012	dbSNP
rs1169246412	2013	dbSNP
rs867720109	2020	dbSNP
rs765634682	2023	dbSNP
rs550597172	2024	dbSNP
rs1360673086	2027	dbSNP
rs557191418	2030	dbSNP
rs1314119509	2036	dbSNP
rs1380420800	2039	dbSNP
rs536653438	2040	dbSNP
rs570875768	2047	dbSNP
rs1270236268	2053	dbSNP
rs1338234459	2054	dbSNP
rs1193700668	2055	dbSNP
rs1286858086	2056	dbSNP
rs1453372564	2061	dbSNP
rs1203371520	2070	dbSNP
rs941339743	2075	dbSNP
rs910006660	2076	dbSNP
rs184667300	2077	dbSNP
rs931821912	2078	dbSNP
rs764619386	2084	dbSNP
rs959159409	2085	dbSNP
rs975988483	2087	dbSNP
rs1426055747	2091	dbSNP
rs965904533	2092	dbSNP
rs1469498697	2096	dbSNP
rs79467542	2112	dbSNP
rs181141984	2113	dbSNP
rs968402495	2117	dbSNP
rs1318961980	2121	dbSNP
rs1019918962	2123	dbSNP
rs1224525212	2124	dbSNP
rs1276118974	2129	dbSNP
rs3088159	2151	dbSNP
rs1204894052	2153	dbSNP
rs890109897	2158	dbSNP
rs529042710	2166	dbSNP
rs1206228520	2169	dbSNP
rs1261722779	2174	dbSNP
rs1445783001	2190	dbSNP
rs188766177	2198	dbSNP
rs79760798	2201	dbSNP
rs865892503	2203	dbSNP
rs759743033	2206	dbSNP
rs1037500873	2208	dbSNP
rs1260942601	2218	dbSNP
rs530946348	2219	dbSNP
rs1174605807	2225	dbSNP
rs1426922009	2230	dbSNP
rs754175272	2231	dbSNP
rs1332045714	2242	dbSNP
rs1380480465	2244	dbSNP
rs1292077691	2245	dbSNP
rs1324906494	2246	dbSNP
rs906033343	2250	dbSNP
rs1342164859	2260	dbSNP
rs1293241567	2261	dbSNP
rs564352611	2264	dbSNP
rs909942325	2268	dbSNP
rs1024456391	2274	dbSNP
rs1240127101	2277	dbSNP
rs1381429487	2285	dbSNP
rs1386039124	2286	dbSNP
rs1322812513	2287	dbSNP
rs1212188360	2290	dbSNP
rs1446060859	2298	dbSNP
rs774162716	2299	dbSNP
rs897434037	2305	dbSNP
rs1254163723	2306	dbSNP
rs372019101	2308	dbSNP
rs550510413	2311	dbSNP
rs917246022	2317	dbSNP
rs545365452	2318	dbSNP
rs993524697	2318	dbSNP
rs958944509	2321	dbSNP
rs941404016	2322	dbSNP
rs1300754195	2324	dbSNP
rs1351891534	2325	dbSNP
rs1391639342	2326	dbSNP
rs1306691506	2327	dbSNP
rs1429481658	2328	dbSNP
rs1247607153	2331	dbSNP
rs1293224507	2337	dbSNP
rs1359353612	2350	dbSNP
rs1220273076	2352	dbSNP
rs573304900	2359	dbSNP
rs1481058720	2366	dbSNP
rs968456953	2372	dbSNP
rs1249532108	2373	dbSNP
rs888408229	2374	dbSNP
rs1466827929	2382	dbSNP
rs545948838	2386	dbSNP
rs1272031305	2387	dbSNP
rs1020015351	2406	dbSNP
rs1049837684	2407	dbSNP
rs932712768	2411	dbSNP
rs1161081221	2415	dbSNP
rs553423323	2416	dbSNP
rs988506300	2420	dbSNP
rs1358458326	2425	dbSNP
rs1297307019	2427	dbSNP
rs975918241	2429	dbSNP
rs542863302	2434	dbSNP
rs573850765	2435	dbSNP
rs368116636	2436	dbSNP
rs1029996932	2443	dbSNP
rs989128664	2444	dbSNP
rs996500690	2445	dbSNP
rs957069018	2446	dbSNP
rs900383631	2453	dbSNP
rs34161137	2459	dbSNP
rs1326822443	2465	dbSNP
rs1263435904	2478	dbSNP
rs1308205200	2482	dbSNP
rs76586605	2485	dbSNP
rs1439027037	2487	dbSNP
rs1370490391	2491	dbSNP
rs1326729127	2492	dbSNP
rs1006037670	2493	dbSNP
rs1484363113	2495	dbSNP
rs3743020	2498	dbSNP
rs1243555226	2500	dbSNP
rs969767467	2501	dbSNP
rs1047208953	2502	dbSNP
rs886257997	2502	dbSNP
rs930071238	2502	dbSNP
rs1167857215	2506	dbSNP
rs111573285	2514	dbSNP
rs1014470036	2515	dbSNP
rs1470763940	2517	dbSNP
rs1337755358	2523	dbSNP
rs1405860216	2538	dbSNP
rs937600015	2553	dbSNP
rs927524788	2555	dbSNP
rs961835279	2562	dbSNP
rs1213993133	2574	dbSNP
rs1293542906	2588	dbSNP
rs1452241658	2590	dbSNP
rs1015855255	2593	dbSNP
rs557034018	2601	dbSNP
rs888470436	2602	dbSNP
rs1322614472	2615	dbSNP
rs1050161483	2618	dbSNP
rs1243705868	2621	dbSNP
rs947585513	2623	dbSNP
rs184267757	2625	dbSNP
rs1452839783	2633	dbSNP
rs192352953	2634	dbSNP
rs1481195087	2641	dbSNP
rs1176770898	2642	dbSNP
rs565645822	2645	dbSNP
rs954448393	2646	dbSNP
rs1672461	2647	dbSNP
rs974406959	2654	dbSNP
rs529096926	2656	dbSNP
rs1276562444	2657	dbSNP
rs1287152115	2674	dbSNP
rs964643805	2680	dbSNP
rs1016215120	2683	dbSNP
rs1006130976	2684	dbSNP
rs1347510574	2686	dbSNP
rs367750272	2687	dbSNP
rs1221395310	2688	dbSNP
rs369930928	2695	dbSNP
rs769855250	2696	dbSNP
rs549987941	2704	dbSNP
rs1258409130	2705	dbSNP
rs935895426	2707	dbSNP
rs1490713875	2708	dbSNP
rs1438799952	2712	dbSNP
rs780637455	2713	dbSNP
rs1334080829	2715	dbSNP
rs1479243892	2716	dbSNP
rs1179367010	2724	dbSNP
rs1409133611	2725	dbSNP
rs994666693	2730	dbSNP
rs55757218	2731	dbSNP
rs1057445730	2745	dbSNP
rs34794954	2753	dbSNP
rs1372923943	2767	dbSNP
rs1302618249	2773	dbSNP
rs1209334	2774	dbSNP
rs1281103323	2782	dbSNP
rs1373727910	2792	dbSNP
rs1223160830	2810	dbSNP
rs1304699692	2817	dbSNP
rs905860038	2818	dbSNP
rs1222658056	2820	dbSNP
rs545114688	2820	dbSNP
rs1434484228	2831	dbSNP
rs1489742157	2833	dbSNP
rs1206131728	2834	dbSNP
rs769639786	2840	dbSNP
rs116136311	2842	dbSNP
rs947636301	2851	dbSNP
rs1175988540	2857	dbSNP
rs911037407	2860	dbSNP
rs913405510	2870	dbSNP
rs992541197	2874	dbSNP
rs1163054478	2875	dbSNP
rs961570719	2885	dbSNP
rs1411890002	2892	dbSNP
rs757579963	2893	dbSNP
rs535809060	2899	dbSNP
rs1246580488	2915	dbSNP
rs1313775231	2918	dbSNP
rs754208242	2930	dbSNP
rs1215971566	2932	dbSNP
rs1273182478	2936	dbSNP
rs117990941	2939	dbSNP
rs866197531	2941	dbSNP
rs1202930690	2949	dbSNP
rs901174360	2950	dbSNP
rs1462181183	2951	dbSNP
rs1208552855	2952	dbSNP
rs1183468199	2966	dbSNP
rs1383477906	2973	dbSNP
rs776543001	2974	dbSNP
rs1168563586	2975	dbSNP
rs950578100	2980	dbSNP
rs1010029961	2985	dbSNP
rs543079710	2987	dbSNP
rs1221186298	2988	dbSNP
rs1407974646	2988	dbSNP
rs761145032	2988	dbSNP
rs1335933704	2999	dbSNP
rs1053335568	3002	dbSNP
rs1338193231	3008	dbSNP
rs1348768029	3017	dbSNP
rs935837120	3027	dbSNP
rs925899714	3029	dbSNP
rs960802478	3031	dbSNP
rs1338396383	3033	dbSNP
rs566738494	3044	dbSNP
rs1265414179	3046	dbSNP
rs948373072	3050	dbSNP
rs1324645803	3056	dbSNP
rs1352938195	3060	dbSNP
rs916876709	3064	dbSNP
rs1203591213	3068	dbSNP
rs573779576	3074	dbSNP
rs939736776	3075	dbSNP
rs908272184	3079	dbSNP
rs905912501	3080	dbSNP
rs1376471935	3086	dbSNP
rs1241561918	3087	dbSNP
rs557160546	3091	dbSNP
rs767532967	3092	dbSNP
rs952908346	3097	dbSNP
rs759781243	3098	dbSNP
rs1175432600	3101	dbSNP
rs1400047238	3103	dbSNP
rs1011792666	3110	dbSNP
rs1318445879	3118	dbSNP
rs1405321641	3119	dbSNP
rs892020350	3120	dbSNP
rs1472633798	3122	dbSNP
rs1028567151	3123	dbSNP
rs933529703	3124	dbSNP
rs1353518377	3125	dbSNP
rs923421625	3125	dbSNP
rs1185735256	3127	dbSNP
rs543605633	3127	dbSNP
rs1485281437	3138	dbSNP
rs1269949687	3140	dbSNP
rs1237881800	3148	dbSNP
rs975602263	3152	dbSNP
rs965351486	3153	dbSNP
rs1283823272	3159	dbSNP
rs984425316	3160	dbSNP
rs1331336783	3161	dbSNP
rs1383625563	3164	dbSNP
rs1019552342	3166	dbSNP
rs1304417435	3172	dbSNP
rs577957697	3174	dbSNP
rs1233250234	3180	dbSNP
rs188024003	3180	dbSNP
rs1299680479	3185	dbSNP
rs1337852133	3190	dbSNP
rs1240401119	3195	dbSNP
rs919203627	3196	dbSNP
rs878993319	3197	dbSNP
rs1352139383	3204	dbSNP
rs1009669654	3205	dbSNP
rs1292555072	3214	dbSNP
rs1490257989	3216	dbSNP
rs1429049257	3232	dbSNP
rs774665128	3238	dbSNP
rs371158745	3258	dbSNP
rs1420586542	3260	dbSNP
rs571976539	3261	dbSNP
rs1033927883	3264	dbSNP
rs771307509	3266	dbSNP
rs1457394795	3276	dbSNP
rs1390244409	3282	dbSNP
rs1385269381	3288	dbSNP
rs1001575725	3290	dbSNP
rs1000469617	3291	dbSNP
rs1021593371	3293	dbSNP
rs1011509892	3297	dbSNP
rs904321057	3303	dbSNP
rs552195330	3305	dbSNP
rs948594701	3306	dbSNP
rs762766325	3307	dbSNP
rs148414195	3308	dbSNP
rs1358749650	3310	dbSNP
rs1414426319	3322	dbSNP
rs1183451540	3327	dbSNP
rs773150325	3328	dbSNP
rs902051966	3330	dbSNP
rs1474307252	3332	dbSNP
rs1196210250	3333	dbSNP
rs569749957	3335	dbSNP
rs376204949	3336	dbSNP
rs908935255	3350	dbSNP
rs539636363	3351	dbSNP
rs1048822859	3356	dbSNP
rs1162082771	3359	dbSNP
rs1374490220	3360	dbSNP
rs1189480640	3365	dbSNP
rs1398500980	3367	dbSNP
rs1466394192	3368	dbSNP
rs1271397466	3370	dbSNP
rs1213123270	3372	dbSNP
rs939683891	3373	dbSNP
rs1337893025	3377	dbSNP
rs1322917046	3378	dbSNP
rs1382692453	3378	dbSNP
rs1394427556	3383	dbSNP
rs1297786253	3385	dbSNP
rs570769705	3391	dbSNP
rs1292644887	3393	dbSNP
rs918908974	3395	dbSNP
rs1213262903	3396	dbSNP
rs1361720380	3397	dbSNP
rs1298738639	3399	dbSNP
rs1205488021	3402	dbSNP
rs746779927	3406	dbSNP
rs1366889564	3407	dbSNP
rs1323375362	3420	dbSNP
rs35432750	3420	dbSNP
rs1179652075	3423	dbSNP
rs983880189	3427	dbSNP
rs1337639730	3432	dbSNP
rs1460461110	3440	dbSNP
rs573985866	3441	dbSNP
rs939226034	3449	dbSNP
rs926484187	3453	dbSNP
rs185540666	3456	dbSNP
rs1408094818	3457	dbSNP
rs1470808924	3468	dbSNP
rs1418569558	3469	dbSNP
rs1188934796	3473	dbSNP
rs921393287	3481	dbSNP
rs530468835	3482	dbSNP
rs975657621	3497	dbSNP
rs970134855	3500	dbSNP
rs1362691774	3504	dbSNP
rs192617080	3510	dbSNP
rs1193163093	3512	dbSNP
rs1347613375	3513	dbSNP
rs559730970	3520	dbSNP
rs1248477592	3523	dbSNP
rs1263498272	3528	dbSNP
rs1175497355	3535	dbSNP
rs144416759	3536	dbSNP
rs956723012	3537	dbSNP
rs1261991977	3544	dbSNP
rs1032847548	3546	dbSNP
rs1032089121	3557	dbSNP
rs375395291	3557	dbSNP
rs997783660	3557	dbSNP
rs1307394282	3563	dbSNP
rs1260666247	3577	dbSNP
rs1275859752	3578	dbSNP
rs1200652476	3582	dbSNP
rs529392412	3590	dbSNP
rs904373057	3596	dbSNP
rs763962155	3599	dbSNP
rs1343942750	3602	dbSNP
rs563432452	3609	dbSNP
rs1022775420	3610	dbSNP
rs1012741433	3611	dbSNP
rs1296404546	3626	dbSNP
rs1367740844	3648	dbSNP
rs1007754269	3650	dbSNP
rs187304996	3651	dbSNP
rs1366576609	3658	dbSNP
rs78192672	3659	dbSNP
rs1309145356	3662	dbSNP
rs939717243	3669	dbSNP
rs564644307	3671	dbSNP
rs1367721847	3672	dbSNP
rs1215325261	3675	dbSNP
rs1283228279	3679	dbSNP
rs746563298	3681	dbSNP
rs779617397	3684	dbSNP
rs1246500624	3690	dbSNP
rs1353840609	3691	dbSNP
rs541672972	3707	dbSNP
rs1431398527	3708	dbSNP
rs1392971560	3711	dbSNP
rs1156970785	3712	dbSNP
rs1387121135	3713	dbSNP
rs1425552798	3718	dbSNP
rs1173270407	3722	dbSNP
rs532427488	3722	dbSNP
rs758062206	3723	dbSNP
rs921448746	3731	dbSNP
rs1434109272	3732	dbSNP
rs780075804	3733	dbSNP
rs1480624726	3734	dbSNP
rs1377607147	3743	dbSNP
rs1239289677	3744	dbSNP
rs1039880220	3746	dbSNP
rs944192668	3748	dbSNP
rs926509288	3749	dbSNP
rs1288787074	3764	dbSNP
rs1319538208	3770	dbSNP
rs1484903961	3771	dbSNP
rs912848022	3772	dbSNP
rs1280001488	3781	dbSNP
rs182928567	3782	dbSNP
rs1312380768	3783	dbSNP
rs1162729524	3792	dbSNP
rs1411963074	3793	dbSNP
rs1411837213	3798	dbSNP
rs754188184	3799	dbSNP
rs1400699289	3807	dbSNP
rs1445973838	3825	dbSNP
rs1221565009	3833	dbSNP
rs1349869620	3834	dbSNP
rs1308569521	3844	dbSNP
rs1411528570	3845	dbSNP
rs149276643	3853	dbSNP
rs1215919277	3859	dbSNP
rs1302008308	3863	dbSNP
rs979937204	3868	dbSNP
rs535442114	3870	dbSNP
rs569012422	3885	dbSNP
rs956281497	3895	dbSNP
rs1031681421	3897	dbSNP
rs753192413	3908	dbSNP
rs1023705880	3911	dbSNP
rs1187274173	3913	dbSNP
rs1012794737	3921	dbSNP
rs34546908	3922	dbSNP
rs1464967298	3925	dbSNP
rs1157093938	3927	dbSNP
rs1168256348	3937	dbSNP
rs370392405	3938	dbSNP
rs1414936640	3940	dbSNP
rs10162754	3941	dbSNP
rs1338139353	3953	dbSNP
rs1432472073	3955	dbSNP
rs1004094011	3964	dbSNP
rs4924583	3973	dbSNP
rs1217242148	3974	dbSNP
rs966051740	3987	dbSNP
rs1412727039	3988	dbSNP
rs1346366224	3990	dbSNP
rs1017897529	3994	dbSNP
rs1007804871	3998	dbSNP
rs1048033329	4005	dbSNP
rs570597902	4007	dbSNP
rs189989229	4012	dbSNP
rs1056152869	4013	dbSNP
rs939038062	4013	dbSNP
rs1257308203	4017	dbSNP
rs1298256124	4020	dbSNP
rs138562837	4021	dbSNP
rs1397705560	4023	dbSNP
rs112784446	4025	dbSNP
rs944216912	4028	dbSNP
rs1331984139	4032	dbSNP
rs904856243	4048	dbSNP
rs563147180	4051	dbSNP
rs1241025269	4052	dbSNP
rs946633975	4055	dbSNP
rs1487446760	4056	dbSNP
rs1483408713	4057	dbSNP
rs1269215609	4058	dbSNP
rs1053132621	4059	dbSNP
rs1197893657	4063	dbSNP
rs1375910186	4068	dbSNP
rs915081460	4069	dbSNP
rs1158761059	4082	dbSNP
rs1213135060	4088	dbSNP
rs549397130	4090	dbSNP
rs763319838	4091	dbSNP
rs1288381570	4109	dbSNP
rs1304511195	4112	dbSNP
rs925513151	4113	dbSNP
rs1230190887	4124	dbSNP
rs1386619542	4133	dbSNP
rs1321961584	4135	dbSNP
rs1353456762	4139	dbSNP
rs1448111419	4141	dbSNP
rs934778431	4143	dbSNP
rs924710377	4145	dbSNP
rs1248448280	4148	dbSNP
rs976178317	4153	dbSNP
rs966472555	4156	dbSNP
rs910552595	4163	dbSNP
rs1264957737	4164	dbSNP
rs979450845	4170	dbSNP
rs952240032	4181	dbSNP
rs1237037683	4183	dbSNP
rs1437353664	4184	dbSNP
rs1166274409	4185	dbSNP
rs1368733363	4188	dbSNP
rs969374012	4194	dbSNP
rs916699558	4197	dbSNP
rs1161861141	4208	dbSNP
rs1399019766	4209	dbSNP
rs529209210	4215	dbSNP
rs1311812170	4223	dbSNP
rs1331180121	4224	dbSNP
rs1027838533	4225	dbSNP
rs563442877	4238	dbSNP
rs959864411	4244	dbSNP
rs1404002006	4248	dbSNP
rs187985326	4250	dbSNP
rs1704382	4252	dbSNP
rs386783425	4253	dbSNP
rs1263470568	4254	dbSNP
rs1389511559	4256	dbSNP
rs1199034533	4260	dbSNP
rs951360396	4261	dbSNP
rs368002083	4266	dbSNP
rs1243303724	4268	dbSNP
rs1003287721	4277	dbSNP
rs564734471	4282	dbSNP
rs1704381	4294	dbSNP
rs1426235945	4296	dbSNP
rs1417762405	4303	dbSNP
rs572749453	4307	dbSNP
rs1398796525	4315	dbSNP
rs899473170	4323	dbSNP
rs1039428700	4325	dbSNP
rs183434681	4326	dbSNP
rs541858198	4336	dbSNP
rs576062343	4342	dbSNP
rs1219060578	4344	dbSNP
rs1464135865	4347	dbSNP
rs1277296419	4349	dbSNP
rs556316708	4350	dbSNP
rs145963959	4354	dbSNP
rs1212089411	4358	dbSNP
rs1210037970	4359	dbSNP
rs1256085248	4360	dbSNP
rs1482604387	4362	dbSNP
rs1198225432	4366	dbSNP
rs1332671495	4367	dbSNP
rs904143918	4370	dbSNP
rs1043992355	4375	dbSNP
rs1193439504	4379	dbSNP
rs1421877046	4383	dbSNP
rs1052341184	4391	dbSNP
rs1177343718	4403	dbSNP
rs1245351513	4406	dbSNP
rs948044344	4415	dbSNP
rs1464661220	4421	dbSNP
rs1342067755	4422	dbSNP
rs916546261	4431	dbSNP
rs1399588316	4437	dbSNP
rs1293128601	4444	dbSNP
rs775444381	4444	dbSNP
rs1297377428	4446	dbSNP
rs992262002	4447	dbSNP
rs1220873156	4451	dbSNP
rs1301972859	4456	dbSNP
rs935187890	4458	dbSNP
rs1230493445	4464	dbSNP
rs1287493063	4468	dbSNP
rs1488427897	4469	dbSNP
rs768644731	4471	dbSNP
rs1322716123	4478	dbSNP
rs1261486633	4488	dbSNP
rs1489710797	4489	dbSNP
rs1040897892	4498	dbSNP
rs1425146524	4499	dbSNP
rs1431911860	4500	dbSNP
rs944733039	4516	dbSNP
rs1380944043	4518	dbSNP
rs907940396	4520	dbSNP
rs910562540	4521	dbSNP
rs1390027581	4523	dbSNP
rs1351827302	4524	dbSNP
rs1164360353	4532	dbSNP
rs982662282	4533	dbSNP
rs1293872908	4543	dbSNP
rs190778364	4545	dbSNP
rs757562843	4547	dbSNP
rs951288717	4555	dbSNP
rs1384961444	4558	dbSNP
rs576850342	4573	dbSNP
rs1026939824	4583	dbSNP
rs1353716902	4592	dbSNP
rs973920564	4595	dbSNP
rs142985603	4603	dbSNP
rs1017864095	4604	dbSNP
rs138409363	4605	dbSNP
rs890901519	4606	dbSNP
rs1180986107	4609	dbSNP
rs1238866457	4615	dbSNP
rs1031165203	4617	dbSNP
rs1035193071	4621	dbSNP
rs546538758	4627	dbSNP
rs186207431	4628	dbSNP
rs1416290216	4629	dbSNP
rs999731759	4631	dbSNP
rs1466760484	4644	dbSNP
rs1406132343	4650	dbSNP
rs117525154	4654	dbSNP
rs969078232	4658	dbSNP
rs1044005533	4664	dbSNP
rs948262511	4673	dbSNP
rs1023274080	4675	dbSNP
rs1010549792	4698	dbSNP
rs150493525	4701	dbSNP
rs1052813814	4706	dbSNP
rs1056507698	4711	dbSNP

- PLoS pathogens, 2012

Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role in viral oncogenesis. To date, only a limited number of EBV miRNA targets have been identified; thus, the role of EBV miRNAs in viral pathogenesis and/or lymphomagenesis is not well defined. Here, we used photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) combined with deep sequencing and computational analysis to comprehensively examine the viral and cellular miRNA targetome in EBV strain B95-8-infected lymphoblastoid cell lines (LCLs). We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs. 24 PAR-CLIP-identified miRNA:3'UTR interactions were confirmed by reporter assays. Our results reveal that EBV miRNAs predominantly target cellular transcripts during latent infection, thereby manipulating the host environment. Furthermore, targets of EBV miRNAs are involved in multiple cellular processes that are directly relevant to viral infection, including innate immunity, cell survival, and cell proliferation. Finally, we present evidence that myc-regulated host miRNAs from the miR-17/92 cluster can regulate latent viral gene expression. This comprehensive survey of the miRNA targetome in EBV-infected B cells represents a key step towards defining the functions of EBV-encoded miRNAs, and potentially, identifying novel therapeutic targets for EBV-associated malignancies.