miRTarBase - #MIRT498711


—
pre-miRNA Information
pre-miRNA hsa-mir-4781   
Genomic Coordinates chr1: 54054079 - 54054154
Description Homo sapiens miR-4781 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4781-3p
Sequence 46| AAUGUUGGAAUCCUCGCUAGAG |67
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs968609764 2 dbSNP
rs899910686 3 dbSNP
rs74085143 4 dbSNP
rs550946107 8 dbSNP
rs747064911 10 dbSNP
rs1352517651 13 dbSNP
rs1436072914 22 dbSNP
Putative Targets

Gene Information
Gene Symbol PGAM5   
Synonyms BXLBV68
Description PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Transcript NM_001170543   
Other Transcripts NM_001170544 , NM_138575   
Expression
Putative miRNA Targets on PGAM5
3'UTR of PGAM5
(miRNA target sites are highlighted)		 
>PGAM5|NM_001170543|3'UTR
   1 GGGCTCCGGCCTCTCCTTCCCTCTGTCCTCCCTGCACAGGCCGCACACACTTAACGTTTTGTTCCCAAGGAGACCGGCGG
  81 AAAGTAGAAACCTGCAATGCTGCATCTGGGAACTGACTTGTGACCAGGCTGAGAAGGGGAGAGTTGGGATCAGACAGCCT
 161 GACTTCTCTGCAGGGTTTTATACCTGACCATGAACCCCCAGGATGGCGTGGGGTTTAAGGTGAAAGCGTCTCACGCACAA
 241 GTCAGGCCTGTTGTGGGGACTTGAAAGAGGCCTGACCCAGACCACCATGTTCGCACCCACAGCTGACCCGTGCTGAGGGT
 321 CCAGGCTCCATTGGCAAAGCCGGTCAGGCACGAGGGCGACTGAGGCACGTGGATGAGGAGGGCACCCAGGTTCTGTTCAC
 401 AACTCACTTCACTTCATACATCCTTTTAATTTCTTAAAACCCTCTTGTCCCTTAAATATTTGTCAATTAAAGATTTTCTG
 481 GCTGGGCACAGTGGCTCACACCTGTATTCCCAGCTACTCAGGAGGCCAGGGTGGGAGGATCACTTGAGCTCAGGAGTTCA
 561 AGACCAGCCTGGACAAGGCAACATAGCGAGACCCTGTCTCTACTAAAAATACAGAACTTAGCTGGGTGTGTCGTGGGCAT
 641 CTAGAGTCCCAGCTACTTGGGAGGCTGAGGTGGGTGGATCACTTGGGCCCGGGAGCTGGAGGCTGCAGTGAGCTGTGATT
 721 GTGTCACTGCACTCCAGCCTGGGCAAGCGAGGGAGACTTAAAGCAATTTTTTCTTTTGAAACGGAGTTTCACTCTTGTTG
 801 CCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACCGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGC
 881 TCCCGAGTAGCTGGGATTACAGTCGCCCACCACCATACCTGGCTAATTTTTTGTATTTTTAGTAAAGACAGGGTTTCATG
 961 GAGAAACCAATATAGAATTGTTCAGGCTGGTCTCGAACTCCCAACCTCAGGTGATTCACCCACCTTGGCCTCCCAAAGTG
1041 CTGGGATTAAAGGTGTGAGCCATCGTGCCTGGCCTAAAAAATTTTTTTTTCTTCATCTGGGTTTTTGCTTTGAAAACAAG
1121 TTTCTCCAAATTTACAGATTTCCTGATGATGTTGGGTCTGAACTCACCAACTTGATTAGGTCTTTAGGGGCCGAGGGACT
1201 AGCCAGCTGCACAGGTGACTGGATGGGGGAGGGGCAGGTGAGGTGGGTCTACAGAGGTGGCTTCGCCTTTGACCTTCATG
1281 CTGGTCTCGGCTGAGGTGACACGCTAGTGACAGCCCAATAGGGGGTTACCCTTATTGAGTAAAATACTTCAGATTGACAG
1361 CTCAATCTTAGTTTGCCTCCAGTTAATCTTTTATGCTTAGGGATTAAATGTGTGGTTTTTTTTTTGTTTTTTTTTTTTTG
1441 GAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTT
1521 CAAACGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTATAGGCGCCCACCACCATGCCTGGCTAATTTTTTATTTT
1601 TAGTAGAGATGGGGTTTCACCGTGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCGTGATCTACCCACCTCGGCCTCCCC
1681 AAGTGCTGGGATTACAGGCGTGAGCTAGCATGCCTGGCCAGGGATTAAAATATTCAAACATGTTGTGTGTACCCAGATAT
1761 GCTGTTAATTTAGGAAAAACAGTACAATTTCTATGAAGTGGTTGTGACTATTTTCTGTAGTCAATACAGTTGGGATATCT
1841 GATCTATTTCTCTGTCTACTTTGGAAATGATTGCATAATAAATAAAATTTTACTGTTTTTTTAAAAGGAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gagaucGCUCCUAAGGUUGUAa 5'
                :|: ||  ||||:|| 
Target 5' gtttcaTGGAGAAACCAATATa 3'
 953 - 974 132.00 -8.70
2 
miRNA  3' gaGAUCGCUCC---------UAAGGUUGUAa 5'
            ||:|| |||         |||| ||||| 
Target 5' gcCTGGCCAGGGATTAAAATATTCAAACATg 3'
 1712 - 1742 132.00 -14.46
3 
miRNA  3' gaGAUC-GCUCCUAAGGUUGUAa 5'
            ||:| | |||    |||||| 
Target 5' gcCTGGACAAGG----CAACATa 3'
 567 - 585 125.00 -9.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN16129748 7 COSMIC
COSN26435351 9 COSMIC
COSN30550926 17 COSMIC
COSN31560935 41 COSMIC
COSN31568571 44 COSMIC
COSN31574192 80 COSMIC
COSN8702099 882 COSMIC
COSN1145253 1108 COSMIC
COSN17903354 1146 COSMIC
COSN1145257 1314 COSMIC
COSN1145261 1360 COSMIC
COSN27342873 1426 COSMIC
COSN27866375 1790 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs770681784 2 dbSNP
rs1179382057 4 dbSNP
rs749972466 4 dbSNP
rs1412761092 5 dbSNP
rs554949568 8 dbSNP
rs901924358 9 dbSNP
rs776792345 10 dbSNP
rs1199544004 11 dbSNP
rs574758603 18 dbSNP
rs1326124624 20 dbSNP
rs554912414 21 dbSNP
rs937523041 22 dbSNP
rs746248069 23 dbSNP
rs1029465218 26 dbSNP
rs1288470071 27 dbSNP
rs1330549056 28 dbSNP
rs1038093253 30 dbSNP
rs540448593 33 dbSNP
rs1004061384 34 dbSNP
rs1016819424 35 dbSNP
rs1211477870 37 dbSNP
rs1395702904 41 dbSNP
rs1270617828 43 dbSNP
rs1470186033 44 dbSNP
rs776168315 44 dbSNP
rs1457165746 45 dbSNP
rs181920919 46 dbSNP
rs532481861 47 dbSNP
rs1473257644 51 dbSNP
rs545974462 53 dbSNP
rs1186316088 56 dbSNP
rs185969066 57 dbSNP
rs890803453 60 dbSNP
rs971161519 67 dbSNP
rs1280025750 68 dbSNP
rs1268032636 69 dbSNP
rs1444489509 73 dbSNP
rs1018225177 74 dbSNP
rs963886162 76 dbSNP
rs979664568 77 dbSNP
rs1338922447 80 dbSNP
rs11548882 82 dbSNP
rs1453069401 91 dbSNP
rs957680836 98 dbSNP
rs1318410284 109 dbSNP
rs988889077 111 dbSNP
rs548527155 119 dbSNP
rs1162118071 124 dbSNP
rs779593146 125 dbSNP
rs913199249 132 dbSNP
rs1369810483 134 dbSNP
rs924781901 138 dbSNP
rs934831165 141 dbSNP
rs568383725 142 dbSNP
rs1207312203 144 dbSNP
rs914811115 145 dbSNP
rs927562434 147 dbSNP
rs937632285 156 dbSNP
rs1209284376 158 dbSNP
rs1354391193 167 dbSNP
rs1267402573 181 dbSNP
rs1247026715 182 dbSNP
rs1364104725 191 dbSNP
rs1428554989 195 dbSNP
rs1173075146 197 dbSNP
rs758707056 203 dbSNP
rs920142344 205 dbSNP
rs929682023 210 dbSNP
rs1404350522 217 dbSNP
rs1392288839 223 dbSNP
rs1163783334 226 dbSNP
rs1039026646 227 dbSNP
rs78655726 228 dbSNP
rs1389146895 229 dbSNP
rs777987420 231 dbSNP
rs547621499 235 dbSNP
rs1048294457 238 dbSNP
rs570650197 256 dbSNP
rs11548877 262 dbSNP
rs1003989352 265 dbSNP
rs1000826085 268 dbSNP
rs771245897 271 dbSNP
rs1227854959 273 dbSNP
rs1032581376 275 dbSNP
rs956572580 276 dbSNP
rs1216079322 277 dbSNP
rs1339892232 282 dbSNP
rs866121452 283 dbSNP
rs1274130064 284 dbSNP
rs1347812864 290 dbSNP
rs898412834 293 dbSNP
rs1012818294 294 dbSNP
rs1303244906 295 dbSNP
rs1408751426 297 dbSNP
rs372672127 303 dbSNP
rs555963954 304 dbSNP
rs569667989 310 dbSNP
rs1022594385 311 dbSNP
rs529452319 313 dbSNP
rs1020343705 316 dbSNP
rs971490810 322 dbSNP
rs1477332643 327 dbSNP
rs1271749498 331 dbSNP
rs1200222409 332 dbSNP
rs1482795288 342 dbSNP
rs78665328 343 dbSNP
rs927356143 347 dbSNP
rs190784426 348 dbSNP
rs1217350968 353 dbSNP
rs745987196 353 dbSNP
rs574797266 359 dbSNP
rs914778250 369 dbSNP
rs1283924444 370 dbSNP
rs143248794 375 dbSNP
rs559361982 380 dbSNP
rs1309425560 386 dbSNP
rs534184902 389 dbSNP
rs975404017 390 dbSNP
rs1355417790 391 dbSNP
rs771664157 396 dbSNP
rs1386782808 412 dbSNP
rs183088260 413 dbSNP
rs1177856132 419 dbSNP
rs1472279268 421 dbSNP
rs1324226583 424 dbSNP
rs943794290 428 dbSNP
rs1179102357 434 dbSNP
rs1039382562 436 dbSNP
rs1047751490 441 dbSNP
rs530610941 443 dbSNP
rs1462525773 445 dbSNP
rs762740806 447 dbSNP
rs1038157502 449 dbSNP
rs1326372375 450 dbSNP
rs1308531456 452 dbSNP
rs1330224042 465 dbSNP
rs1377977691 465 dbSNP
rs1282106565 467 dbSNP
rs1450887706 471 dbSNP
rs546310084 475 dbSNP
rs1230694133 478 dbSNP
rs1408793570 485 dbSNP
rs1337920884 487 dbSNP
rs562855168 488 dbSNP
rs1464196922 490 dbSNP
rs1009367502 491 dbSNP
rs898340799 497 dbSNP
rs768330350 500 dbSNP
rs7486982 508 dbSNP
rs1180359398 510 dbSNP
rs1268756164 511 dbSNP
rs1449393562 521 dbSNP
rs971452339 526 dbSNP
rs1044721014 527 dbSNP
rs1252539029 533 dbSNP
rs907148129 534 dbSNP
rs1034730839 535 dbSNP
rs541858989 536 dbSNP
rs1320646688 549 dbSNP
rs1031383152 551 dbSNP
rs78601523 553 dbSNP
rs1410991141 563 dbSNP
rs1316188796 570 dbSNP
rs1434907073 571 dbSNP
rs1011338625 573 dbSNP
rs972546564 578 dbSNP
rs1164051053 586 dbSNP
rs1291187163 588 dbSNP
rs1027252342 591 dbSNP
rs1349402448 594 dbSNP
rs1162859348 599 dbSNP
rs1021763590 602 dbSNP
rs1426800982 604 dbSNP
rs1262385323 606 dbSNP
rs1392896390 610 dbSNP
rs964894787 613 dbSNP
rs1385216421 618 dbSNP
rs974993454 627 dbSNP
rs527625182 633 dbSNP
rs111264981 634 dbSNP
rs1487853155 640 dbSNP
rs912773017 645 dbSNP
rs955007488 647 dbSNP
rs1224185343 649 dbSNP
rs767314880 651 dbSNP
rs943758291 660 dbSNP
rs1273556991 667 dbSNP
rs1228086531 668 dbSNP
rs983852195 673 dbSNP
rs1316702162 674 dbSNP
rs1366926374 675 dbSNP
rs1244993710 677 dbSNP
rs1266902032 679 dbSNP
rs907913203 691 dbSNP
rs868242520 692 dbSNP
rs865920110 694 dbSNP
rs942083446 720 dbSNP
rs564301022 723 dbSNP
rs919733190 725 dbSNP
rs948549446 728 dbSNP
rs1374619619 735 dbSNP
rs1044263631 744 dbSNP
rs907113508 748 dbSNP
rs938647618 749 dbSNP
rs532967009 750 dbSNP
rs1490382109 754 dbSNP
rs1190733690 755 dbSNP
rs891471277 756 dbSNP
rs1202625970 766 dbSNP
rs1034458674 767 dbSNP
rs113627918 767 dbSNP
rs549914233 768 dbSNP
rs182965076 773 dbSNP
rs1228685761 776 dbSNP
rs1021396633 783 dbSNP
rs765784572 784 dbSNP
rs1225402166 785 dbSNP
rs1027426808 792 dbSNP
rs1307611850 793 dbSNP
rs951608591 795 dbSNP
rs1398296023 798 dbSNP
rs386768324 801 dbSNP
rs11147017 802 dbSNP
rs11147018 804 dbSNP
rs1384618965 806 dbSNP
rs965536691 808 dbSNP
rs955118721 815 dbSNP
rs1410587331 817 dbSNP
rs983673417 824 dbSNP
rs565319156 825 dbSNP
rs1196712170 828 dbSNP
rs963364461 830 dbSNP
rs973405454 831 dbSNP
rs916648198 835 dbSNP
rs1324290977 836 dbSNP
rs752004251 838 dbSNP
rs570512091 839 dbSNP
rs1237051572 842 dbSNP
rs913605258 851 dbSNP
rs945261575 861 dbSNP
rs1395218537 866 dbSNP
rs1314400683 868 dbSNP
rs1046301854 869 dbSNP
rs781426659 870 dbSNP
rs928495263 872 dbSNP
rs906353086 875 dbSNP
rs937874176 883 dbSNP
rs1386340975 885 dbSNP
rs1186427290 888 dbSNP
rs1363992548 888 dbSNP
rs554037103 896 dbSNP
rs187638603 905 dbSNP
rs756188804 906 dbSNP
rs947021463 909 dbSNP
rs1042767117 910 dbSNP
rs1273902997 912 dbSNP
rs887112345 914 dbSNP
rs900246856 917 dbSNP
rs1244378151 919 dbSNP
rs1483450495 921 dbSNP
rs1004427205 934 dbSNP
rs1316872499 943 dbSNP
rs1202004964 951 dbSNP
rs1228271912 953 dbSNP
rs1019894689 954 dbSNP
rs1383360982 955 dbSNP
rs1258502388 964 dbSNP
rs995971541 971 dbSNP
rs771538555 974 dbSNP
rs997011382 984 dbSNP
rs1028933213 987 dbSNP
rs866909044 991 dbSNP
rs775035224 995 dbSNP
rs76891258 996 dbSNP
rs989643162 1001 dbSNP
rs1191695270 1004 dbSNP
rs1451471774 1005 dbSNP
rs11548879 1010 dbSNP
rs1221915655 1015 dbSNP
rs556691096 1015 dbSNP
rs1357547655 1016 dbSNP
rs1015118737 1020 dbSNP
rs1167260071 1026 dbSNP
rs966368150 1028 dbSNP
rs1341220419 1032 dbSNP
rs146445595 1033 dbSNP
rs994797454 1037 dbSNP
rs1326445701 1043 dbSNP
rs775511515 1045 dbSNP
rs1322293359 1046 dbSNP
rs1402636897 1050 dbSNP
rs937951465 1053 dbSNP
rs1303433158 1058 dbSNP
rs1425638246 1060 dbSNP
rs1400561073 1061 dbSNP
rs1023672774 1065 dbSNP
rs768687532 1066 dbSNP
rs1476666313 1067 dbSNP
rs1374215199 1070 dbSNP
rs920460219 1075 dbSNP
rs982220982 1081 dbSNP
rs1223534211 1082 dbSNP
rs1436943062 1082 dbSNP
rs928435683 1082 dbSNP
rs959913804 1083 dbSNP
rs1225629034 1084 dbSNP
rs1339991358 1091 dbSNP
rs1294730374 1100 dbSNP
rs1274228834 1113 dbSNP
rs1221130651 1115 dbSNP
rs988671872 1118 dbSNP
rs1041094706 1120 dbSNP
rs370375759 1120 dbSNP
rs1327260641 1128 dbSNP
rs542328034 1130 dbSNP
rs1397808415 1134 dbSNP
rs1176358061 1136 dbSNP
rs34448345 1139 dbSNP
rs746225806 1139 dbSNP
rs1431545491 1141 dbSNP
rs947325713 1152 dbSNP
rs1042736572 1153 dbSNP
rs921620408 1159 dbSNP
rs1206325968 1165 dbSNP
rs866476308 1171 dbSNP
rs1438237353 1173 dbSNP
rs931682555 1175 dbSNP
rs1201728155 1183 dbSNP
rs1010632585 1188 dbSNP
rs1263236329 1188 dbSNP
rs1051538242 1189 dbSNP
rs890589612 1192 dbSNP
rs562093382 1193 dbSNP
rs748002358 1194 dbSNP
rs1466287131 1196 dbSNP
rs899419123 1206 dbSNP
rs771798335 1213 dbSNP
rs572468252 1220 dbSNP
rs1409015057 1225 dbSNP
rs142960169 1225 dbSNP
rs969434678 1226 dbSNP
rs1406039489 1235 dbSNP
rs541377462 1245 dbSNP
rs1376220900 1249 dbSNP
rs1242307747 1250 dbSNP
rs1469659264 1253 dbSNP
rs1320801505 1254 dbSNP
rs920399383 1265 dbSNP
rs373243321 1266 dbSNP
rs1214432451 1279 dbSNP
rs1048478882 1285 dbSNP
rs1367731011 1287 dbSNP
rs114593046 1289 dbSNP
rs760199033 1290 dbSNP
rs765986272 1294 dbSNP
rs1451004506 1298 dbSNP
rs1240593770 1299 dbSNP
rs1385582565 1301 dbSNP
rs192415797 1303 dbSNP
rs545806481 1304 dbSNP
rs1430053314 1307 dbSNP
rs1343542460 1308 dbSNP
rs968587552 1315 dbSNP
rs1041063698 1320 dbSNP
rs549729814 1320 dbSNP
rs978702188 1322 dbSNP
rs1331430209 1324 dbSNP
rs921569585 1325 dbSNP
rs1446272425 1328 dbSNP
rs931678684 1332 dbSNP
rs763349982 1336 dbSNP
rs866242420 1350 dbSNP
rs563461670 1351 dbSNP
rs1185892325 1352 dbSNP
rs1484567152 1353 dbSNP
rs1243356270 1358 dbSNP
rs911644961 1359 dbSNP
rs4883606 1360 dbSNP
rs372650481 1366 dbSNP
rs548642998 1369 dbSNP
rs1414681665 1370 dbSNP
rs899342485 1372 dbSNP
rs995027727 1378 dbSNP
rs1455279961 1383 dbSNP
rs1157920567 1385 dbSNP
rs1045334016 1389 dbSNP
rs1362075330 1394 dbSNP
rs530112420 1395 dbSNP
rs550148898 1396 dbSNP
rs905473090 1397 dbSNP
rs1290696465 1398 dbSNP
rs1003526117 1400 dbSNP
rs565380622 1402 dbSNP
rs1438071227 1403 dbSNP
rs1426273936 1413 dbSNP
rs200157487 1413 dbSNP
rs1426646629 1414 dbSNP
rs201016993 1414 dbSNP
rs1035469547 1415 dbSNP
rs1491102121 1415 dbSNP
rs1204339482 1416 dbSNP
rs1266418882 1416 dbSNP
rs1298435463 1416 dbSNP
rs149771944 1416 dbSNP
rs755856895 1416 dbSNP
rs892545591 1416 dbSNP
rs1345001254 1417 dbSNP
rs796457007 1417 dbSNP
rs1020087816 1418 dbSNP
rs1281539496 1421 dbSNP
rs1407005152 1422 dbSNP
rs1291682575 1423 dbSNP
rs1344860723 1424 dbSNP
rs1391794878 1424 dbSNP
rs1491215869 1425 dbSNP
rs112835068 1426 dbSNP
rs200188284 1426 dbSNP
rs796586281 1426 dbSNP
rs1171330214 1427 dbSNP
rs1201068773 1427 dbSNP
rs12322297 1427 dbSNP
rs1249466841 1427 dbSNP
rs1491316083 1427 dbSNP
rs386378313 1427 dbSNP
rs12304942 1428 dbSNP
rs1491560873 1428 dbSNP
rs201902442 1429 dbSNP
rs1198491153 1430 dbSNP
rs1326825489 1431 dbSNP
rs1222225029 1436 dbSNP
rs1283892626 1439 dbSNP
rs1322397427 1440 dbSNP
rs1223915885 1441 dbSNP
rs1306622834 1445 dbSNP
rs12423124 1446 dbSNP
rs1490315134 1447 dbSNP
rs1183573680 1451 dbSNP
rs1254337861 1454 dbSNP
rs1468935996 1455 dbSNP
rs1176263253 1458 dbSNP
rs1021104372 1464 dbSNP
rs1362807336 1473 dbSNP
rs758231876 1476 dbSNP
rs968556566 1484 dbSNP
rs1179719059 1485 dbSNP
rs1162036963 1486 dbSNP
rs979055409 1487 dbSNP
rs571081492 1492 dbSNP
rs1309793909 1493 dbSNP
rs1348376044 1496 dbSNP
rs1318443470 1499 dbSNP
rs953460141 1502 dbSNP
rs540092832 1506 dbSNP
rs1380226646 1508 dbSNP
rs1034659693 1523 dbSNP
rs766265706 1526 dbSNP
rs959298105 1527 dbSNP
rs1380599030 1534 dbSNP
rs990727158 1538 dbSNP
rs1444456567 1540 dbSNP
rs1383878768 1541 dbSNP
rs1190262991 1552 dbSNP
rs1358824512 1558 dbSNP
rs778699957 1560 dbSNP
rs987148925 1566 dbSNP
rs1206424020 1567 dbSNP
rs1027996908 1568 dbSNP
rs1486971855 1569 dbSNP
rs556514883 1572 dbSNP
rs570209725 1573 dbSNP
rs1357046769 1574 dbSNP
rs1316987402 1575 dbSNP
rs1204327448 1580 dbSNP
rs1142465 1589 dbSNP
rs1325840044 1590 dbSNP
rs75774730 1596 dbSNP
rs1315606564 1604 dbSNP
rs1383455800 1607 dbSNP
rs983263786 1609 dbSNP
rs1238437803 1611 dbSNP
rs183479242 1615 dbSNP
rs1165448074 1616 dbSNP
rs907748786 1618 dbSNP
rs1373081944 1620 dbSNP
rs940078477 1622 dbSNP
rs372222230 1623 dbSNP
rs1384021327 1628 dbSNP
rs1222026692 1633 dbSNP
rs1449608127 1638 dbSNP
rs1170404221 1639 dbSNP
rs1291738209 1642 dbSNP
rs187692595 1642 dbSNP
rs1409129840 1643 dbSNP
rs922604753 1645 dbSNP
rs932657909 1646 dbSNP
rs1268393787 1649 dbSNP
rs1228907592 1656 dbSNP
rs1334506678 1657 dbSNP
rs1282173159 1662 dbSNP
rs1402733584 1669 dbSNP
rs1367114719 1672 dbSNP
rs1325943077 1673 dbSNP
rs1049781956 1675 dbSNP
rs920734492 1676 dbSNP
rs1396383461 1679 dbSNP
rs1360713051 1681 dbSNP
rs930800367 1683 dbSNP
rs1045663943 1684 dbSNP
rs1198857608 1690 dbSNP
rs111613153 1701 dbSNP
rs1248713374 1703 dbSNP
rs76087830 1711 dbSNP
rs1437038328 1716 dbSNP
rs1042528251 1719 dbSNP
rs147917329 1730 dbSNP
rs1317928584 1735 dbSNP
rs112279152 1736 dbSNP
rs1261953416 1736 dbSNP
rs796634241 1736 dbSNP
rs1035199005 1740 dbSNP
rs1275127800 1741 dbSNP
rs1437575208 1741 dbSNP
rs1335582779 1742 dbSNP
rs572531106 1746 dbSNP
rs894780224 1748 dbSNP
rs1175760874 1756 dbSNP
rs1468344039 1758 dbSNP
rs1012311175 1760 dbSNP
rs767670327 1761 dbSNP
rs1469378727 1770 dbSNP
rs1230977296 1777 dbSNP
rs1229279430 1778 dbSNP
rs951939980 1781 dbSNP
rs1458155570 1784 dbSNP
rs892474335 1785 dbSNP
rs1242504901 1788 dbSNP
rs750637594 1789 dbSNP
rs983400442 1792 dbSNP
rs1014731510 1799 dbSNP
rs1278845529 1800 dbSNP
rs1259402537 1802 dbSNP
rs1422079882 1804 dbSNP
rs1348169614 1806 dbSNP
rs1307522109 1807 dbSNP
rs1214531102 1809 dbSNP
rs1449515337 1809 dbSNP
rs1336675375 1815 dbSNP
rs1279696354 1818 dbSNP
rs965886440 1818 dbSNP
rs1335033746 1820 dbSNP
rs1400328783 1820 dbSNP
rs1009628949 1824 dbSNP
rs1201365860 1829 dbSNP
rs541438833 1830 dbSNP
rs922666462 1847 dbSNP
rs754387208 1849 dbSNP
rs1242227148 1851 dbSNP
rs932776949 1851 dbSNP
rs1444888503 1855 dbSNP
rs903966426 1857 dbSNP
rs1287777309 1866 dbSNP
rs1242706886 1868 dbSNP
rs1000031393 1872 dbSNP
rs1314881147 1877 dbSNP
rs1227121143 1879 dbSNP
rs1382040710 1886 dbSNP
rs1029278033 1891 dbSNP
rs1358838739 1894 dbSNP
rs1430154664 1894 dbSNP
rs915281451 1896 dbSNP
rs1420045321 1904 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545215. RNA binding protein: AGO4. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 192111.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 192111.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gagaucgcuccuaagGUUGUAa 5'
                         |||||| 
Target 5' --------------gCAACAUa 3'
 		1 - 8
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 192111.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 5 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated ...

- Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology.

Article - Farazi TA; Ten Hoeve JJ; Brown M; et al.
- Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
CLIP-seq Support 1 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545215
Method / RBP PAR-CLIP / AGO4
Cell line / Condition HEK293 / Control
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000498926.2 | 3UTR | GGCAACAUAGCGAGACCCUGUCUCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000498926.2 | 3UTR | GCAACAUAGCGAGACCCUGUCUCUAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUACUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset SRR1045082
Method / RBP PAR-CLIP / AGO2
Cell line / Condition MCF7 / Untreated
Location of target site ENST00000498926.2 | 3UTR | CAACAUAGCGAGACCCUGUCUCUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24398324 / SRX388831
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
204 hsa-miR-4781-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071728 CCNK cyclin K 2 2
MIRT184858 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT205881 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT218699 ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2 2
MIRT223783 OXR1 oxidation resistance 1 2 2
MIRT242435 GAN gigaxonin 2 2
MIRT306825 NCBP2 nuclear cap binding protein subunit 2 2 2
MIRT334170 CCND1 cyclin D1 2 6
MIRT339617 TMPO thymopoietin 2 2
MIRT400371 C2ORF68 chromosome 2 open reading frame 68 2 2
MIRT445533 KIF1B kinesin family member 1B 2 4
MIRT450273 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT450701 RORA RAR related orphan receptor A 2 2
MIRT451160 C19orf53 chromosome 19 open reading frame 53 2 2
MIRT453775 NUCB1 nucleobindin 1 2 10
MIRT453884 IFRD1 interferon related developmental regulator 1 2 12
MIRT454238 OSBPL10 oxysterol binding protein like 10 2 9
MIRT458661 PAGR1 PAXIP1 associated glutamate rich protein 1 2 12
MIRT466948 STAU1 staufen double-stranded RNA binding protein 1 2 2
MIRT470278 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 2
MIRT471144 PHF19 PHD finger protein 19 2 2
MIRT471873 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT476739 FOXN2 forkhead box N2 2 2
MIRT480453 C16orf72 chromosome 16 open reading frame 72 2 6
MIRT482107 AKT3 AKT serine/threonine kinase 3 2 4
MIRT483374 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT484063 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT496329 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT498659 AP3B2 adaptor related protein complex 3 beta 2 subunit 2 4
MIRT498711 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 10
MIRT499322 ZNF485 zinc finger protein 485 2 6
MIRT499711 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 2 10
MIRT499767 CIRH1A UTP4, small subunit processome component 2 6
MIRT499912 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 8
MIRT504946 ZSWIM6 zinc finger SWIM-type containing 6 2 4
MIRT505377 TMEM154 transmembrane protein 154 2 4
MIRT508778 GSG1 germ cell associated 1 2 2
MIRT509793 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT512421 LAYN layilin 2 4
MIRT513321 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT513592 DCTN6 dynactin subunit 6 2 2
MIRT514785 RBM4B RNA binding motif protein 4B 2 2
MIRT514859 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 2
MIRT515122 LMOD3 leiomodin 3 2 2
MIRT515271 CSNK1E casein kinase 1 epsilon 2 2
MIRT515594 FBXL13 F-box and leucine rich repeat protein 13 2 2
MIRT515880 PLXDC2 plexin domain containing 2 2 2
MIRT515908 AGTPBP1 ATP/GTP binding protein 1 2 2
MIRT515960 C9orf156 tRNA methyltransferase O 2 2
MIRT517210 OTUD6A OTU deubiquitinase 6A 2 2
MIRT517330 ZNF347 zinc finger protein 347 2 2
MIRT517480 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT517594 ZNF579 zinc finger protein 579 2 4
MIRT517676 TRIM72 tripartite motif containing 72 2 2
MIRT518215 TRMT10B tRNA methyltransferase 10B 2 2
MIRT518583 ATP8B1 ATPase phospholipid transporting 8B1 2 2
MIRT518777 ZFP14 ZFP14 zinc finger protein 2 2
MIRT519094 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 4
MIRT519112 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT519400 DNASE2 deoxyribonuclease 2, lysosomal 2 4
MIRT519446 GLA galactosidase alpha 2 2
MIRT519476 SPTLC2 serine palmitoyltransferase long chain base subunit 2 2 2
MIRT519711 ZNF584 zinc finger protein 584 2 4
MIRT521409 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT521522 QSOX1 quiescin sulfhydryl oxidase 1 2 2
MIRT522652 MANEAL mannosidase endo-alpha like 2 2
MIRT523505 GMPS guanine monophosphate synthase 2 4
MIRT523795 FAM63B MINDY lysine 48 deubiquitinase 2 2 2
MIRT524062 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT524136 DMXL1 Dmx like 1 2 2
MIRT524192 DENND4C DENN domain containing 4C 2 4
MIRT525925 KIAA0391 KIAA0391 2 2
MIRT528021 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT528685 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT528769 CD1D CD1d molecule 2 2
MIRT529373 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 2 4
MIRT529469 ZNF546 zinc finger protein 546 2 2
MIRT529641 ZNF621 zinc finger protein 621 2 2
MIRT530681 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT530752 GPR82 G protein-coupled receptor 82 2 2
MIRT531628 TM4SF5 transmembrane 4 L six family member 5 2 4
MIRT531649 C19orf52 translocase of inner mitochondrial membrane 29 2 4
MIRT532179 SEC14L5 SEC14 like lipid binding 5 2 4
MIRT532219 CCDC117 coiled-coil domain containing 117 2 2
MIRT534238 SLC25A16 solute carrier family 25 member 16 2 4
MIRT539952 SLC30A5 solute carrier family 30 member 5 2 2
MIRT540179 MB21D1 Mab-21 domain containing 1 2 2
MIRT540466 ZNF71 zinc finger protein 71 2 2
MIRT540560 PPIC peptidylprolyl isomerase C 2 2
MIRT543265 ZNF662 zinc finger protein 662 2 2
MIRT543596 KIAA1549 KIAA1549 2 2
MIRT543971 RNF20 ring finger protein 20 2 2
MIRT544053 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT544605 DCAF5 DDB1 and CUL4 associated factor 5 2 2
MIRT544679 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT547627 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT550668 TRAF1 TNF receptor associated factor 1 2 2
MIRT551533 EMB embigin 2 2
MIRT552443 ZNF449 zinc finger protein 449 2 2
MIRT559265 BAG4 BCL2 associated athanogene 4 2 4
MIRT562479 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT564211 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT565973 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT570524 SHH sonic hedgehog 2 2
MIRT575307 Osbpl10 oxysterol binding protein-like 10 2 6
MIRT618212 C22orf39 chromosome 22 open reading frame 39 2 2
MIRT620115 HARBI1 harbinger transposase derived 1 2 2
MIRT624062 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT626083 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT629868 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT630750 COG6 component of oligomeric golgi complex 6 2 2
MIRT631002 ZNF573 zinc finger protein 573 2 2
MIRT631100 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT631290 SGSM1 small G protein signaling modulator 1 2 2
MIRT631337 CD300E CD300e molecule 2 2
MIRT631532 MYO6 myosin VI 2 2
MIRT631644 WDR91 WD repeat domain 91 2 4
MIRT632788 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT633282 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT633593 ABRACL ABRA C-terminal like 2 2
MIRT634074 PLIN3 perilipin 3 2 2
MIRT634163 YME1L1 YME1 like 1 ATPase 2 2
MIRT634257 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT634679 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT638384 RABL3 RAB, member of RAS oncogene family like 3 2 2
MIRT638687 GCLM glutamate-cysteine ligase modifier subunit 2 2
MIRT640311 PRR13 proline rich 13 2 2
MIRT641132 NPHP3 nephrocystin 3 2 2
MIRT642315 FPR1 formyl peptide receptor 1 2 2
MIRT643703 KIAA0586 KIAA0586 2 2
MIRT644322 NFKBID NFKB inhibitor delta 2 2
MIRT645741 POLR3A RNA polymerase III subunit A 2 2
MIRT646975 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 2
MIRT648064 TRMT10C tRNA methyltransferase 10C, mitochondrial RNase P subunit 2 2
MIRT648536 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 2 2
MIRT649294 NEK8 NIMA related kinase 8 2 2
MIRT650014 KLB klotho beta 2 2
MIRT650551 YIPF4 Yip1 domain family member 4 2 2
MIRT651796 UTP6 UTP6, small subunit processome component 2 2
MIRT652647 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT653548 SLC38A7 solute carrier family 38 member 7 2 2
MIRT653895 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT655470 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT657764 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT659118 DENND6A DENN domain containing 6A 2 2
MIRT659377 CREG2 cellular repressor of E1A stimulated genes 2 2 2
MIRT659836 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT659954 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT660258 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT663268 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 2 2
MIRT663766 ZNF285 zinc finger protein 285 2 2
MIRT666198 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT669763 ZNF101 zinc finger protein 101 2 4
MIRT669933 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT670007 GPR156 G protein-coupled receptor 156 2 4
MIRT670465 RSBN1L round spermatid basic protein 1 like 2 2
MIRT670868 IFNAR1 interferon alpha and beta receptor subunit 1 2 4
MIRT671313 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT671959 SPPL3 signal peptide peptidase like 3 2 2
MIRT672281 SHE Src homology 2 domain containing E 2 2
MIRT673654 CYCS cytochrome c, somatic 2 2
MIRT674063 ATXN3 ataxin 3 2 2
MIRT674423 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT674438 MIOX myo-inositol oxygenase 2 4
MIRT674483 BCL2L15 BCL2 like 15 2 2
MIRT675478 NUBPL nucleotide binding protein like 2 2
MIRT675648 TTPAL alpha tocopherol transfer protein like 2 2
MIRT675981 FAM126B family with sequence similarity 126 member B 2 2
MIRT676251 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT677652 HAUS2 HAUS augmin like complex subunit 2 2 2
MIRT682718 KIAA1456 KIAA1456 2 2
MIRT687545 MOB1B MOB kinase activator 1B 2 2
MIRT689620 AKAP6 A-kinase anchoring protein 6 2 2
MIRT690035 CCDC90B coiled-coil domain containing 90B 2 2
MIRT691449 CXorf36 chromosome X open reading frame 36 2 2
MIRT691549 FLYWCH2 FLYWCH family member 2 2 2
MIRT691737 LARS leucyl-tRNA synthetase 2 2
MIRT692638 SUSD1 sushi domain containing 1 2 2
MIRT693866 IYD iodotyrosine deiodinase 2 2
MIRT693979 ZNF70 zinc finger protein 70 2 2
MIRT694150 CYP27C1 cytochrome P450 family 27 subfamily C member 1 2 2
MIRT695492 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT695547 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT696023 TYRO3 TYRO3 protein tyrosine kinase 2 2
MIRT696402 CORO7 coronin 7 2 2
MIRT703028 HEATR5A HEAT repeat containing 5A 2 2
MIRT703559 FKBP14 FK506 binding protein 14 2 2
MIRT705036 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT705120 C4orf29 abhydrolase domain containing 18 2 2
MIRT706611 CYB5B cytochrome b5 type B 2 2
MIRT706635 PNPT1 polyribonucleotide nucleotidyltransferase 1 2 2
MIRT706730 RFK riboflavin kinase 2 2
MIRT706868 MAFF MAF bZIP transcription factor F 2 2
MIRT707020 RRP36 ribosomal RNA processing 36 2 2
MIRT707036 ACTR5 ARP5 actin related protein 5 homolog 2 2
MIRT707125 ZNF154 zinc finger protein 154 2 2
MIRT707390 SLC35F6 solute carrier family 35 member F6 2 2
MIRT708664 LYRM7 LYR motif containing 7 2 2
MIRT713010 BBX BBX, HMG-box containing 2 2
MIRT717314 TRAF3IP1 TRAF3 interacting protein 1 2 2
MIRT721912 C6orf201 chromosome 6 open reading frame 201 2 2
MIRT723050 YTHDC1 YTH domain containing 1 2 2
MIRT725038 NDUFAF7 NADH:ubiquinone oxidoreductase complex assembly factor 7 2 2
MIRT755316 SMAD5 SMAD family member 5 4 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4781-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4781-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4781-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4781-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)

Error report submission